Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and terfenadine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with terfenadine in 10 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(terfenadine)
Trials
(terfenadine)
Recent Studies (post-2010) (terfenadine)
9,1561875521,751568346

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)terfenadine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.93
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.231
Epidermal growth factor receptorHomo sapiens (human)3.566
Tyrosine-protein kinase FynHomo sapiens (human)6.123
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.928
ATP-dependent translocase ABCB1Homo sapiens (human)1.8167
Cytochrome P450 3A4Homo sapiens (human)0.32
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.9
D(2) dopamine receptorHomo sapiens (human)6.167
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)0.35
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.34
Alpha-2C adrenergic receptorHomo sapiens (human)3.748
DRattus norvegicus (Norway rat)0.1288
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.1288
Substance-K receptorHomo sapiens (human)2.677
D(1A) dopamine receptorHomo sapiens (human)2.673
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2.34
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.928
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.1288
Alpha-1D adrenergic receptorHomo sapiens (human)2.34
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.255
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.231
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.094
Alpha-1A adrenergic receptorHomo sapiens (human)2.34
Histamine H1 receptorHomo sapiens (human)0.0115
Alpha-1B adrenergic receptorHomo sapiens (human)2.34
D(3) dopamine receptorHomo sapiens (human)1.503
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.048
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.34
5-hydroxytryptamine receptor 6Homo sapiens (human)1.306
Cytochrome P450 2J2Homo sapiens (human)8.1
C-C chemokine receptor type 5Homo sapiens (human)1.103
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.93
Sodium-dependent dopamine transporter Homo sapiens (human)0.255
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2233
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.93
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.125
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.971

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB1
Bewtra, AK; Hopp, RJ; Miyagawa, H; Nair, NM; Okada, C; Sugiyama, H; Townley, RG1
Coyle, AJ; Lefort, J; Vargaftig, BB1
Baber, NS; Gill, D; James, I; Jordan, S; Sciberras, DG1
Chapman, ID; Hoshiko, K; Morley, J1
Agrawal, DK; Bewtra, AK; Hopp, RJ; Townley, RG1
Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C1
Eda, R; Hopp, RJ; Townley, RG1
Archer, CB; Brooks, J; Burton, JL; Sansom, JE1
He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H1

Trials

4 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and terfenadine

ArticleYear
Effect of terfenadine on neutrophil and eosinophil chemotactic activities after inhalation of platelet-activating factor in vivo and on neutrophil chemotaxis in vitro.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:3

    Topics: Administration, Inhalation; Adult; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Eosinophils; Female; Humans; In Vitro Techniques; Leukocyte Count; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Terfenadine

1992
The role of histamine in the acute inflammatory responses to intradermal platelet activating factor.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:1

    Topics: Benzhydryl Compounds; Double-Blind Method; Drug Hypersensitivity; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Terfenadine

1991
Terfenadine effect on the bronchoconstriction, dermal response, and leukopenia induced by platelet-activating factor.
    Chest, 1991, Volume: 100, Issue:4

    Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Histamine; Humans; Leukopenia; Male; Platelet Activating Factor; Skin Tests; Terfenadine; Time Factors

1991
Effects of H1- and H2-antihistamines on platelet-activating factor and bradykinin-induced inflammatory responses in human skin.
    Clinical and experimental dermatology, 1996, Volume: 21, Issue:1

    Topics: Administration, Oral; Bradykinin; Cimetidine; Codeine; Double-Blind Method; Doxepin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Platelet Activating Factor; Skin; Terfenadine; Urticaria

1996

Other Studies

6 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and terfenadine

ArticleYear
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles

1992
The effect of cetirizine on antigen-dependent leucopenia in the guinea-pig.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Animals; Benzeneacetamides; Benzhydryl Compounds; Blood Platelets; Cetirizine; Female; Guinea Pigs; Histamine H1 Antagonists; Hydroxamic Acids; Hydroxyzine; In Vitro Techniques; Leukocyte Count; Leukopenia; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrilamine; Terfenadine

1991
Histamine(H1) antagonists and airway hyperreactivity in the guinea-pig.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Airway Resistance; Animals; Bronchoconstriction; Guinea Pigs; Histamine; Histamine H1 Antagonists; Injections, Intravenous; Male; Platelet Activating Factor; Respiratory Hypersensitivity; Terfenadine

1991
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan

1993
Effect of terfenadine on human eosinophil and neutrophil chemotactic response and generation of superoxide.
    Annals of allergy, 1994, Volume: 73, Issue:2

    Topics: Adult; Asthma; Calcimycin; Cell Degranulation; Cell Separation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rhinitis; Superoxides; Terfenadine

1994
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Release; Inflammation; Lactones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Peritoneum; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Reptilian Proteins; Snake Venoms; Terfenadine

2013