1-hexadecyl-2-acetyl-glycero-3-phosphocholine and tcv 309

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with tcv 309 in 56 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (tcv 309)	Trials (tcv 309)	Recent Studies (post-2010) (tcv 309)
9,156	187	552	68	2	0

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	46 (82.14)	18.2507
2000's	10 (17.86)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Banaś, M; Dembiński, A; Konturek, SJ; Stachura, J; Tomaszewska, R; Warzecha, Z	1
Dembinski, A; Gustaw, P; Jaworek, J; Konturek, PJ; Konturek, SJ; Stachura, J; Tomaszewska, R; Warzecha, Z	1
Imura, Y; Kawamura, M; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S	1
Imura, Y; Maezaki, N; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S	1
Buurman, WA; Daemen, JH; Kootstra, G; Kurvers, HA; Tangelder, GJ; Tiebosch, AT; Yin, M	1
Okano, S; Tagawa, M; Urakawa, N	2
Jaworek, J; Konturek, SJ	1
King, KA; Lim, SL; Pang, CC	1
Ishida, H; Oh-ishi, S; Ueno, A	1
Aguilera, JG; Croxatto, HB; Velasquez, LA	1
Fukuoka, T; Nakajima, Y; Nakano, H	2
Ide, S; Kawahara, K; Nagayasu, T; Sasaki, N; Shingu, H; Tagawa, T; Takahashi, T; Tomita, M; Yamamoto, S	1
Booster, MH; Buurman, WA; Daemen, JH; Kondracki, S; Kootstra, G; Kurvers, HA; Tangelder, GJ; Yin, M	1
Altavilla, D; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Sardella, A; Squadrito, F; Squadrito, G; Urna, G; Zingarelli, B	1
Fujiwara, S; Kawamura, M; Kitayoshi, T; Nishikawa, K; Takatani, M; Terashita, Z	1
Hirohata, M; Kikuchi, T; Sigemori, M; Tokutomi, T	1
Inada, M; Iwasaka, T; Izuoka, T; Kimura, Y; Kitashiro, S; Tamura, K; Tamura, T	1
Hack, CE; Imai, Y; Kuipers, B; Levi, M; ten Cate, H; ten Cate, JW; van der Poll, T; van Deventer, SJ	1
Inada, M; Iwasaka, T; Izuoka, T; Kimura, Y; Kitashiro, S; Tamura, K; Tamura, T; Tsuji, H	1
Abe, T; Katoh, S; Kodama, I; Koike, A; Toyama, J	1
Iwao, H; Kim, S; Miura, K; Yamanaka, S; Yukimura, T	1
Endo, C; Hoshi, K; Nakanishi, H; Okawa, T; Sato, A; Suzuki, H; Suzuki, Y	1
Aosaki, N; Minezaki, K; Nakamura, H; Nakazawa, H; Ohsuzu, F; Senoh, M; Tuji, C	1
Imura, Y; Kawamura, M; Nishikawa, K; Shino, A; Terashita, Z	1
Kamochi, M; Koga, K; Matsumoto, T; Ogata, M; Sata, T; Shigematsu, A; Takenaka, I; Yoshida, S	1
Gunji, H; Harada, H; Hasegawa, T; Kaneko, F; Matsuzaki, M; Ono, I	1
Baba, S; Nakamura, S; Nishiyama, R; Suzuki, S	1
Akamine, S; Kawahara, K; Muraoka, S; Nakamura, A; Tagawa, T; Takahashi, T; Tomita, M; Yamamoto, S	1
Aarden, LA; Hack, CE; Jansen, J; Levi, M; ten Cate, H; ten Cate, JW; van der Poll, T; van Deventer, SJ	1
Buurman, WA; Daemen, JW; Kootstra, G; Yin, M	1
Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A	1
Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N	1
Ebara, T; Imanishi, M; Iwao, H; Kim, S; Matsuura, T; Miura, K; Yamano, Y	1
Johnston, JM; Kanzaki, H; Matsubara, T; Matsuoka, S; Okada, H; Sanezumi, M; Yasuda, K	1
Bourgeois, M; Buurman, WA; Froon, AM; Greve, JW; Langemeijer, HJ; Ulrich, C; van der Linden, CJ	1
Egashira, K; Fukumoto, Y; Kadokami, T; Katsumata, N; Kozai, T; Kuwata, K; Shimokawa, H; Takeshita, A; Yamawaki, T	1
Iwasaka, T; Izuoka, T; Jikuhara, T; Kitashiro, S; Sugiura, T; Takayama, Y; Tamura, T; Taniguchi, H	1
Ansley, DM; English, JC; Godin, DV; Kim, CW; Lee, JU; Loucks, EB; Qayumi, AK	1
Izumi, T; Koyama, S; Kubo, K; Miura, M; Nagai, S; Nomura, H; Sato, E; Yamashita, T	1
Ashida, Y; Kitao, S; Kobayashi, K; Kyotani, K; Mochizuki, T; Nishizono, K; Scott, MA; Tsuchiya, R; Yamada, T	1
Akimoto, T; Azumi, Y; Ichihara, T; Idei, H; Kuroda, Y; Nagahata, Y; Nomura, H	1
Akizuki, E; Ishihara, K; Liang, J; Matsuda, T; Matsumura, F; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y	1
Duronio, V; Horley, K; Keown, P; Nikbakht-Sangari, M; Qayumi, AK	1
Carboni, GL; Hillinger, S; Schmid, RA; Schneiter, D; Stammberger, U; Weder, W	1
Keown, PA; Nikbakht-Sangari, M; Qayumi, AK	1
Baba, S; Fujise, Y; Kojima, Y; Konno, H; Kurachi, K; Nakamura, S; Okamoto, K; Sakaguchi, T; Serizawa, A; Suzuki, S; Tsuchiya, Y	1
Kubota, S; Mafune, N; Miyatake, T; Miyazaki, K; Murashita, T; Watanabe, S; Yasuda, K	1
Buurman, WA; Froon, AH; Greve, JW; Poeze, M; Ramsay, G	1
Hasegawa, T; Iwase, M; Izawa, H; Kitaichi, K; Nagasaka, T; Takagi, K; Wang, L; Yokota, M	1
Kawasaki, T; Kobayashi, Y; Murohisa, G; Nakamura, H; Nakamura, S	1
Aktary, FM; Godin, DV; Granville, DJ; Hong, JM; Loucks, EB; McManus, BM; Qayumi, AK; Rahimian, R; Walley, KR	1
Kawasaki, N; Kawasaki, T; Ma, BY; Nakagawa, T; Nakamura, K; Oka, S; Uemura, K; Yamamoto, H	1
Feldman, MJ; Kieffer, CA; Miller, DV; Morris, GP; Paterson, WG	1
Beuk, RJ; Heineman, E; Maassen, RL; Oude Egbrink, MG; Quaedackers, JS; Tangelder, GJ	1

Trials

2 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and tcv 309

Article	Year
Treatment with the platelet-activating factor antagonist TCV-309 in patients with severe systemic inflammatory response syndrome: a prospective, multi-center, double-blind, randomized phase II trial. Shock (Augusta, Ga.), 1996, Volume: 5, Issue:5 Topics: Adult; Aged; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines; Treatment Outcome	1996
Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group. Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4 Topics: Adult; Aged; APACHE; Double-Blind Method; Female; Humans; Inflammation Mediators; Isoquinolines; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Shock, Septic; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines	2000

Article

Year

Treatment with the platelet-activating factor antagonist TCV-309 in patients with severe systemic inflammatory response syndrome: a prospective, multi-center, double-blind, randomized phase II trial.

Shock (Augusta, Ga.), 1996, Volume: 5, Issue:5

Topics: Adult; Aged; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines; Treatment Outcome

1996

Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group.

Shock (Augusta, Ga.), 2000, Volume: 14, Issue:4

Topics: Adult; Aged; APACHE; Double-Blind Method; Female; Humans; Inflammation Mediators; Isoquinolines; Male; Middle Aged; Multiple Organ Failure; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Shock, Septic; Systemic Inflammatory Response Syndrome; Tetrahydroisoquinolines

2000

Other Studies

54 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and tcv 309

Article	Year
Platelet activating factor (PAF) inhibitor (TCV-309) reduces caerulein- and PAF-induced pancreatitis. A morphologic and functional study in the rat. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1992, Volume: 43, Issue:4 Topics: Acute Disease; Animals; Ceruletide; Isoquinolines; Male; Pancreas; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Regional Blood Flow; Tetrahydroisoquinolines	1992
Role of platelet activating factor in pathogenesis of acute pancreatitis in rats. Gut, 1992, Volume: 33, Issue:9 Topics: Acute Disease; Amylases; Animals; Ceruletide; Isoquinolines; Male; Pancreatic Juice; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines	1992
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: Anaphylaxis; Animals; Azepines; Furans; Hemolysis; Humans; Hypotension; Isoquinolines; Male; Microsomes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Tetrahydroisoquinolines; Triazoles	1992
Platelet activating factor (PAF) antagonists: development of a highly potent PAF antagonist, TCV-309. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B Topics: Animals; Azepines; Humans; Isoquinolines; Molecular Structure; Niacinamide; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Rats; Structure-Activity Relationship; Tetrahydroisoquinolines; Triazoles	1991
Platelet-activating factor antagonist TCV-309 protects rat kidneys against ischemia-reperfusion injury. Transplantation proceedings, 1995, Volume: 27, Issue:5 Topics: Animals; Ischemia; Isoquinolines; Kidney; Kidney Tubules, Proximal; Male; Microvilli; Mitochondrial Swelling; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Tetrahydroisoquinolines; Time Factors	1995
Effect of TCV-309, a novel platelet activating factor antagonist, on hemodynamics in dogs with endotoxin-induced shock. The Journal of veterinary medical science, 1995, Volume: 57, Issue:2 Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Escherichia coli; Heart Rate; Hemodynamics; Isoquinolines; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Stroke Volume; Tetrahydroisoquinolines; Vascular Resistance	1995
Effects of prostaglandin of E, F and I series, leukotriene C and platelet activating factor on amylase release from isolated rat pancreatic acini. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:4 Topics: Acetamides; Amylases; Animals; Bethanechol Compounds; Ceruletide; Chromones; Dinoprostone; Epoprostenol; Indomethacin; Isoquinolines; Leukotriene C4; Male; Pancreas; Phenyl Ethers; Platelet Activating Factor; Prostaglandin Antagonists; Prostaglandins; Prostaglandins F; Prostaglandins F, Synthetic; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines	1993
Regional haemodynamic effects of platelet activating factor in the rat. European journal of pharmacology, 1995, Aug-04, Volume: 281, Issue:2 Topics: Animals; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Injections, Intravenous; Isoquinolines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tetrahydroisoquinolines	1995
Comparative study of endotoxin-induced hypotension in kininogen-deficient rats with that in normal rats. British journal of pharmacology, 1995, Volume: 114, Issue:6 Topics: Amino Acid Sequence; Animals; Bradykinin; Dose-Response Relationship, Drug; Endotoxins; Hypotension; Isoquinolines; Kininogens; Lipopolysaccharides; Male; Molecular Sequence Data; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred BN; Rats, Mutant Strains; Rats, Sprague-Dawley; Reference Values; Tetrahydroisoquinolines	1995
Possible role of platelet-activating factor in embryonic signaling during oviductal transport in the hamster. Biology of reproduction, 1995, Volume: 52, Issue:6 Topics: Animals; Cricetinae; Culture Techniques; Diterpenes; Embryo, Mammalian; Female; Ginkgolides; Indomethacin; Isoquinolines; Lactones; Masoprocol; Ovum Transport; Platelet Activating Factor; Platelet Count; Pregnancy; Pyridinium Compounds; Signal Transduction; Tetrahydroisoquinolines	1995
The platelet activating factor as a pivotal mediator of shock after liver ischemia. Surgery today, 1995, Volume: 25, Issue:4 Topics: Animals; Hypotension; Ischemia; Isoquinolines; Liver; Liver Failure; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Shock; Tetrahydroisoquinolines	1995
Donor administration of PAF antagonist (TCV-309) enhances lung preservation. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Animals; Carbon Dioxide; Dogs; Isoquinolines; Lung; Lung Transplantation; Organ Preservation; Oxygen; Partial Pressure; Peroxidase; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Reperfusion; Reperfusion Injury; Tetrahydroisoquinolines	1995
Beneficial effect of platelet-activating factor antagonist TCV-309 on renal ischemia-reperfusion injury. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Animals; Creatinine; Ischemia; Isoquinolines; Kidney; Male; Microscopy, Video; Organ Preservation; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Temperature; Tetrahydroisoquinolines	1995
TCV-309, a novel platelet activating factor antagonist, inhibits leukocyte accumulation and protects against splanchnic artery occlusion shock. Agents and actions, 1994, Volume: 42, Issue:3-4 Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Ileum; Isoquinolines; Leukocyte Count; Leukocytes; Lung; Male; Neutrophils; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splenic Artery; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha	1994
Effects of TCV-309, a novel PAF antagonist, on circulatory shock and hematological abnormality induced by endotoxin in dogs. Journal of lipid mediators and cell signalling, 1994, Volume: 9, Issue:3 Topics: Animals; Blood Circulation; Blood Pressure; Disease Models, Animal; Dogs; Heart; Hematologic Diseases; Hemodynamics; Isoquinolines; Male; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines; Time Factors	1994
Effect of platelet-activating factor antagonist on brain injury in rats. Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Animals; Brain Edema; Brain Injuries; Brain Ischemia; Cerebral Cortex; Isoquinolines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Wistar; Specific Gravity; Tetrahydroisoquinolines; Water-Electrolyte Balance	1994
The effects of platelet activating factor antagonist, TCV309, on the relationship between electrophysiological and mechanical status during myocardial ischemia and reperfusion. Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723 Topics: Action Potentials; Animals; Dogs; Electrophysiology; Hemodynamics; Isoquinolines; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Activating Factor; Pyridinium Compounds; Tetrahydroisoquinolines	1994
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees. Journal of immunology (Baltimore, Md. : 1950), 1994, Mar-01, Volume: 152, Issue:5 Topics: alpha 1-Antitrypsin; Animals; Cytokines; Disease Models, Animal; Endotoxins; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Interleukin-8; Isoquinolines; Leukocyte Count; Leukocyte Elastase; Neutrophils; Pan troglodytes; Pancreatic Elastase; Platelet Activating Factor; Pyridinium Compounds; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tetrahydroisoquinolines; Toxemia; Tumor Necrosis Factor-alpha	1994
The effect of platelet-activating-factor antagonist TCV-309 on arrhythmias and functional recovery during myocardial reperfusion. Coronary artery disease, 1994, Volume: 5, Issue:3 Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Isoquinolines; Myocardial Contraction; Myocardial Reperfusion Injury; Platelet Activating Factor; Pyridinium Compounds; Tachycardia, Ventricular; Tetrahydroisoquinolines; Ventricular Fibrillation; Ventricular Function, Left	1994
Role of platelet activating factor in ischaemia-reperfusion injury of isolated rabbit hearts: protective effect of a specific platelet activating factor antagonist, TCV-309. Cardiovascular research, 1993, Volume: 27, Issue:8 Topics: Animals; Coronary Circulation; Isoquinolines; Myocardial Reperfusion Injury; Perfusion; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Tetrahydroisoquinolines; Ventricular Function, Left	1993
Platelet-activating factor as a vasodepressive mediator of liver ischemia. Transplantation proceedings, 1993, Volume: 25, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Ischemia; Isoquinolines; Liver; Male; Molecular Structure; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Thromboxane B2	1993
Effect of the platelet-activating factor antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the haemodynamic changes in canine experimental endotoxic shock. British journal of pharmacology, 1993, Volume: 110, Issue:4 Topics: Animals; Dogs; Endotoxins; Female; Hemodynamics; Ibuprofen; Isoquinolines; Male; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines	1993
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor]. Nihon Sanka Fujinka Gakkai zasshi, 1994, Volume: 46, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; Isoquinolines; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pregnancy; Pyridinium Compounds; Rats; Tetrahydroisoquinolines; Uterine Contraction	1994
Early release of neutrophil chemotactic factor from isolated rat heart subjected to regional ischaemia followed by reperfusion. Cardiovascular research, 1993, Volume: 27, Issue:12 Topics: Animals; Chemotaxis; Disease Models, Animal; Hot Temperature; Interleukin-8; Isoquinolines; Male; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors	1993
Inhibitory effect of TCV-309, a novel platelet activating factor (PAF) antagonist, on endotoxin-induced disseminated intravascular coagulation in rats: possible role of PAF in tissue factor generation. Thrombosis research, 1993, May-15, Volume: 70, Issue:4 Topics: Animals; Disease Models, Animal; Disseminated Intravascular Coagulation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Isoquinolines; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Thromboplastin	1993
An antagonist of platelet-activating factor suppresses endotoxin-induced tumor necrosis factor and mortality in mice pretreated with carrageenan. Infection and immunity, 1993, Volume: 61, Issue:2 Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Isoquinolines; Leukotrienes; Lipopolysaccharides; Male; Mice; Platelet Activating Factor; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha	1993
Effects of a platelet activating factor antagonist on oedema formation following burns. Burns : journal of the International Society for Burn Injuries, 1993, Volume: 19, Issue:3 Topics: Animals; Body Water; Burns; Edema; Isoquinolines; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Skin; Superoxide Dismutase; Tetrahydroisoquinolines	1993
Platelet-activating factor in hepatic ischemia/reperfusion injury. The effects of a PAF antagonist combined with a prostaglandin I2 analogue. Transplantation, 1993, Volume: 55, Issue:6 Topics: Animals; Bile; Endotoxins; Epoprostenol; Glutathione; Ischemia; Isoquinolines; Liver; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Reperfusion Injury; Tetrahydroisoquinolines	1993
The effect of the platelet-activating factor inhibitor TCV-309 on reperfusion injury in a canine model of ischemic lung. Transplantation, 1993, Volume: 55, Issue:6 Topics: Animals; Dogs; Ischemia; Isoquinolines; Leukocyte Count; Lung; Lung Compliance; Platelet Activating Factor; Pulmonary Circulation; Pyridinium Compounds; Reperfusion Injury; Tetrahydroisoquinolines; Vascular Resistance	1993
Effect of platelet activating factor antagonist (TCV-309) on lung injury in dogs with experimentally endotoxin-induced shock. The Journal of veterinary medical science, 1995, Volume: 57, Issue:4 Topics: Animals; Dogs; Escherichia coli; Isoquinolines; Lipopolysaccharides; Lung; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Edema; Pulmonary Surfactants; Pyridinium Compounds; Shock, Septic; Tetrahydroisoquinolines	1995
Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6. Scandinavian journal of immunology, 1996, Volume: 43, Issue:1 Topics: Animals; Antibodies, Monoclonal; Endotoxins; Escherichia coli; Injections, Intravenous; Interleukin-10; Interleukin-6; Interleukin-8; Isoquinolines; Pan troglodytes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Tetrahydroisoquinolines; Toxemia	1996
The PAF antagonist TCV-309 reduces graft PMN infiltration and enhances early function of 24-hour-preserved rat kidneys with long warm ischemia. Transplantation, 1996, May-27, Volume: 61, Issue:10 Topics: Animals; Hot Temperature; Immunity, Cellular; Ischemia; Isoquinolines; Kidney; Kidney Cortex; Kidney Transplantation; Lung; Macrophages; Monocytes; Neutrophils; Organ Preservation; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Inbred Lew; Reperfusion Injury; Tetrahydroisoquinolines; Time Factors	1996
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions. Japanese journal of pharmacology, 1996, Volume: 70, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines	1996
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs. British journal of pharmacology, 1996, Volume: 118, Issue:4 Topics: Animals; Benzoquinones; Biphenyl Compounds; Cell Count; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Eicosanoids; Female; Heptanoic Acids; Hypotension; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Pyridinium Compounds; Tetrahydroisoquinolines; Vascular Resistance	1996
Role of platelet-activating factor and prostanoids in hemodynamic changes in rat experimental endotoxic shock. Japanese journal of pharmacology, 1996, Volume: 71, Issue:3 Topics: Animals; Bridged Bicyclo Compounds; Fatty Acids, Monounsaturated; Hemodynamics; Ibuprofen; Isoquinolines; Male; Platelet Activating Factor; Prostaglandins; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Shock, Septic; Tetrahydroisoquinolines	1996
Platelet-activating factor (PAF) and PAF acetylhydrolase activity in rat uterus and placenta during the late stages of pregnancy. Biology of reproduction, 1997, Volume: 56, Issue:4 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Biological Assay; Female; Isoquinolines; Phospholipases A; Phospholipid Ethers; Placenta; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy, Animal; Pyridinium Compounds; Rabbits; Rats; Rats, Wistar; Reference Values; Tetrahydroisoquinolines; Time Factors; Uterus	1997
Platelet activating factor causes hyperconstriction at the inflammatory coronary lesions in pigs in vivo. Coronary artery disease, 1997, Volume: 8, Issue:7 Topics: Animals; Coronary Vasospasm; Coronary Vessels; Dinoprost; Drug Synergism; Histamine; Interleukin-1; Isoquinolines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Pyridinium Compounds; Serotonin; Swine; Tetrahydroisoquinolines; Vasoconstriction	1997
Role of platelet-activating factor on extravascular lung water after coronary reperfusion in dogs. The Japanese journal of physiology, 1998, Volume: 48, Issue:2 Topics: Animals; Coronary Vessels; Dogs; Extravascular Lung Water; Hemodynamics; Isoquinolines; Ligation; Myocardial Reperfusion; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Tetrahydroisoquinolines	1998
The role of platelet-activating factor in regional myocardial ischemia-reperfusion injury. The Annals of thoracic surgery, 1998, Volume: 65, Issue:6 Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Pressure; Cardiac Output; Cardiac Volume; Disease Models, Animal; Female; Heart Arrest; Hemodynamics; Isoquinolines; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Random Allocation; Stroke Volume; Swine; Tetrahydroisoquinolines; Ventricular Fibrillation; Ventricular Function	1998
Bradykinin stimulates type II alveolar cells to release neutrophil and monocyte chemotactic activity and inflammatory cytokines. The American journal of pathology, 1998, Volume: 153, Issue:6 Topics: Antibodies; Bradykinin; Bradykinin Receptor Antagonists; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemotactic Factors; Culture Media, Conditioned; Cycloheximide; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Isoquinolines; Leukotriene B4; Lipoxygenase Inhibitors; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Alveoli; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Tetrahydroisoquinolines; Transforming Growth Factor beta	1998
Role of platelet activating factor in development of thrombocytopenia and neutropenia in dogs with endotoxemia. American journal of veterinary research, 1999, Volume: 60, Issue:2 Topics: Animals; Blood Coagulation Tests; Dog Diseases; Dogs; Endotoxemia; Female; Isoquinolines; Leukocyte Count; Lipopolysaccharides; Male; Neutropenia; Pilot Projects; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Count; Pyridinium Compounds; Radioimmunoassay; Tetrahydroisoquinolines; Thrombocytopenia	1999
Role of platelet activating factor on severity of ischemic colitis. Diseases of the colon and rectum, 1999, Volume: 42, Issue:2 Topics: Animals; Colitis, Ischemic; Colon; Intestinal Mucosa; Isoquinolines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Random Allocation; Rats; Rats, Wistar; Tetrahydroisoquinolines; Thiobarbiturates	1999
Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats. Pancreas, 1999, Volume: 18, Issue:4 Topics: Animals; Ceruletide; Chemokines, CXC; Chemotactic Factors; Growth Inhibitors; Growth Substances; Hemorrhage; Intercellular Signaling Peptides and Proteins; Isoquinolines; Kinetics; Lipopolysaccharides; Lung; Lung Diseases; Macrophages, Alveolar; Male; Pancreatitis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Tetrahydroisoquinolines	1999
Platelet-activating factor plays a role in the mechanism of major histocompatibility complex in T lymphocytes. Immunological investigations, 1999, Volume: 28, Issue:4 Topics: Animals; CD3 Complex; Flow Cytometry; Histocompatibility Antigens Class II; Isoquinolines; Lung Transplantation; Lymphocyte Activation; Phytohemagglutinins; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Swine; T-Lymphocytes; Tetrahydroisoquinolines	1999
Combined treatment with endothelin- and PAF-antagonists reduces posttransplant lung ischemia/reperfusion injury. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:9 Topics: Animals; Drug Therapy, Combination; Endothelin Receptor Antagonists; Isoquinolines; Lipid Peroxidation; Lung; Lung Transplantation; Male; Oxygen; Peptides, Cyclic; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred F344; Reperfusion Injury; Tetrahydroisoquinolines; Thiobarbituric Acid Reactive Substances	1999
The role of inflammatory mediators in the mechanism of the host immune response induced by ischemia-reperfusion injury. Immunological investigations, 2000, Volume: 29, Issue:1 Topics: Alprostadil; Animals; Female; Histocompatibility Antigens Class II; Inflammation Mediators; Infusions, Intravenous; Isoquinolines; Platelet Activating Factor; Pyridinium Compounds; Regression Analysis; Reperfusion Injury; Swine; T-Lymphocyte Subsets; Tetrahydroisoquinolines; Up-Regulation	2000
The roles of platelet-activating factor and endothelin-1 in renal damage after total hepatic ischemia and reperfusion. Transplantation, 2000, Jun-15, Volume: 69, Issue:11 Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Blood Urea Nitrogen; Creatinine; Endothelin-1; Ischemia; Isoquinolines; Kidney; Liver; Liver Circulation; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Tetrahydroisoquinolines	2000
Analysis of cardiac function during hyperacute rejection: effects of PAF antagonist, TXA(2) inhibitor/antagonists, and nitroglycerin. Transplantation proceedings, 2000, Volume: 32, Issue:5 Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Graft Rejection; Guinea Pigs; Heart Transplantation; In Vitro Techniques; Isoquinolines; Nitroglycerin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines; Thromboxane A2; Transplantation, Heterologous; Ventricular Function, Left	2000
Cardiac functional and structural alterations induced by endotoxin in rats: importance of platelet-activating factor. Critical care medicine, 2001, Volume: 29, Issue:3 Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Echocardiography; Electrocardiography; Endotoxemia; Epinephrine; Hematocrit; Isoquinolines; Klebsiella Infections; Klebsiella pneumoniae; Lipopolysaccharides; Male; Nitrates; Nitrites; Norepinephrine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prospective Studies; Pyridinium Compounds; Rats; Rats, Wistar; Systole; Tetrahydroisoquinolines; Time Factors; Ventricular Dysfunction, Left	2001
Involvement of platelet-activating factor in hepatic apoptosis and necrosis in chronic ethanol-fed rats given endotoxin. Liver, 2002, Volume: 22, Issue:5 Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Therapy, Combination; Escherichia coli; Ethanol; Fas Ligand Protein; fas Receptor; Hepatitis, Alcoholic; Immunoenzyme Techniques; In Situ Nick-End Labeling; Isoquinolines; Lipopolysaccharides; Liver; Male; Membrane Glycoproteins; Necrosis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines	2002
Role of platelet activating factor in cardiac dysfunction, apoptosis and nitric oxide synthase mRNA expression in the ischemic-reperfused rabbit heart. The Canadian journal of cardiology, 2003, Mar-15, Volume: 19, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Coronary Circulation; DNA Fragmentation; Gene Expression; In Vitro Techniques; Isoquinolines; Myocardial Contraction; Myocardial Reperfusion Injury; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; RNA, Messenger; Tetrahydroisoquinolines; Time Factors	2003
Superoxide production from human polymorphonuclear leukocytes by human mannan-binding protein (MBP). Glycoconjugate journal, 2004, Volume: 21, Issue:1-2 Topics: Calcium; Cell Aggregation; Dose-Response Relationship, Drug; Humans; Ligands; Mannose; Mannose-Binding Lectin; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Polyvinyls; Pyridinium Compounds; Recombinant Proteins; Superoxides; Tetrahydroisoquinolines; Time Factors	2004
Role of platelet-activating factor in acid-induced esophageal mucosal injury. Digestive diseases and sciences, 2007, Volume: 52, Issue:8 Topics: Animals; Cromolyn Sodium; Esophagitis, Peptic; Gastroesophageal Reflux; Mast Cells; Opossums; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Tetrahydroisoquinolines; Thioxanthenes; Xanthones	2007
Leucocyte and platelet adhesion in different layers of the small bowel during experimental total warm ischaemia and reperfusion. The British journal of surgery, 2008, Volume: 95, Issue:10 Topics: Animals; Antibodies, Monoclonal; Blood Flow Velocity; Capillaries; Cell Adhesion; Intercellular Adhesion Molecule-1; Intestine, Small; Leukocytes; Microcirculation; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Pyridinium Compounds; Random Allocation; Rats; Rats, Inbred Lew; Reperfusion; Reperfusion Injury; Tetrahydroisoquinolines; Warm Ischemia	2008