Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and tacrolimus

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with tacrolimus in 7 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(tacrolimus)
Trials
(tacrolimus)
Recent Studies (post-2010) (tacrolimus)
9,15618755217,7572,3196,661

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)tacrolimus (IC50)
Bile salt export pumpHomo sapiens (human)7.18
Cytochrome P450 3A4Homo sapiens (human)0.58
Cytochrome P450 3A5Homo sapiens (human)0.385
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.0148
Splicing factor 3B subunit 3Homo sapiens (human)0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.7

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asako, H; Baethge, BA; Granger, DN; Kubes, P; Wolf, RE1
Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C1
Fukao, K; Fukunaga, K; Iijima, T; Otsuka, M; Takada, Y; Taniguchi, H; Todoroki, T; Yuzawa, K1
Fukao, K; Fukunaga, K; Otsuka, M; Takada, Y; Taniguchi, H; Yuzawa, K1
Al-Harbi, SA; Bak, I; Blasig, IE; Ferdinandy, P; Haines, DD; Mahmoud, FF; Tosaki, A1
Fukao, K; Fukunaga, K; Gu, M; Ishiguro, S; Otsuka, M; Seino, K; Takada, Y; Taniguchi, H; Yuzawa, K1
Dierkhising, RA; Henke, SA; Kita, H; Madaan, A; Matsuwaki, Y; Plager, DA; Squillace, DL1

Other Studies

7 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and tacrolimus

ArticleYear
Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules.
    Transplantation, 1992, Volume: 54, Issue:4

    Topics: Animals; Capillaries; Cell Adhesion; Cell Movement; Cyclosporine; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tacrolimus; Venules

1992
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan

1993
Prolonged hepatic warm ischemia in non-heart-beating donors: protective effects of FK506 and a platelet activating factor antagonist in porcine liver transplantation.
    Surgery, 1998, Volume: 123, Issue:6

    Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Immunosuppressive Agents; Ischemia; Liver; Liver Transplantation; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Swine; Tacrolimus

1998
Energy metabolism of hepatic allografts subjected to prolonged warm ischemia and pharmacologic modulation with FK506 and platelet activating factor antagonist.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: Adenine Nucleotides; Animals; Aspartate Aminotransferases; Energy Metabolism; Graft Survival; Ischemia; Liver; Liver Transplantation; Organ Preservation; Piperidines; Platelet Activating Factor; Postoperative Period; Pyridinium Compounds; Swine; Tacrolimus; Temperature; Transplantation, Homologous

1998
Cardioprotective effects of the calcineurin inhibitor FK506 and the PAF receptor antagonist and free radical scavenger, EGb 761, in isolated ischemic/reperfused rat hearts.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:1

    Topics: Animals; Calcineurin Inhibitors; Dose-Response Relationship, Drug; Electrocardiography; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Hemodynamics; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Plant Extracts; Plants, Medicinal; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Tacrolimus

2000
Improvement of allograft viability with organs procured from non-heart-beating donors in porcine liver transplantation.
    Transplantation proceedings, 2000, Volume: 32, Issue:2

    Topics: Animals; Endothelin-1; Graft Survival; Heart Arrest; Liver Transplantation; Peptides, Cyclic; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Swine; Tacrolimus; Time Factors; Tissue and Organ Harvesting; Transplantation, Homologous

2000
Pimecrolimus reduces eosinophil activation associated with calcium mobilization.
    International archives of allergy and immunology, 2009, Volume: 149, Issue:2

    Topics: Calcineurin Inhibitors; Calcium; Cell Degranulation; Cell Survival; Cells, Cultured; Eosinophil-Derived Neurotoxin; Eosinophils; Humans; Immunoglobulin A, Secretory; Interleukin-5; Platelet Activating Factor; Superoxides; Tacrolimus

2009