1-hexadecyl-2-acetyl-glycero-3-phosphocholine and substance p

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with substance p in 65 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (substance p)	Trials (substance p)	Recent Studies (post-2010) (substance p)
9,156	187	552	17,289	277	2,010

Protein Interaction Comparison

Protein	Taxonomy	substance p (IC50)
Substance-P receptor	Rattus norvegicus (Norway rat)	0.0005
Substance-K receptor	Rattus norvegicus (Norway rat)	0.2
Substance-K receptor	Homo sapiens (human)	0.2455
Substance-P receptor	Homo sapiens (human)	0.0011
Neuromedin-K receptor	Homo sapiens (human)	0.125
Substance-K receptor	Mesocricetus auratus (golden hamster)	0.148

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (13.85)	18.7374
1990's	44 (67.69)	18.2507
2000's	9 (13.85)	29.6817
2010's	3 (4.62)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bousquet, J; Chanez, P; Godard, P; Lacoste, JY; Michel, FB	1
Agrawal, DK; Numao, T	1
Gilfillan, AM; Hope, WC; Patel, BJ; Welton, AF; Wiggan, GA	1
Foreman, JC; Hayes, NA; McLeod, J	1
Church, MK; Thomas, G	1
Ishihara, H; Masuda, T; Sasaki, H; Sasaki, T; Satoh, M; Shimura, S; Takishima, T	1
Brunelleschi, S; Fantozzi, R; Giotti, A; Tarli, S	1
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D	1
McDonald, DM; Nadel, JA; Piedimonte, G	1
Cramer, R; Dri, P; Patriarca, P; Romano, M; Spessotto, P	1
Bousquet, J; Braquet, P; Chanez, P; Damon, M; Godard, P; Mencia Huerta, JM; Michel, FB; Rabier, M	1
Drazen, JM; Martins, MA; Shore, SA	1
Ashmarin, IP; Brodskiĭ, LI; Dugina, TN; Kireeva, EG; Kogan, AE; Strukova, SM	1
Brain, SD; Williams, TJ	1
Di Marzo, V; Morris, HR; Tippins, JR	1
Gerard, NP	1
Hedqvist, P; Lindbom, L; Ohlén, A; Raud, J; Thureson-Klein, A	1
Drazen, JM; Galli, SJ; Gerard, NP; Martin, TR	1
Holzer, P; Lippe, IT	1
Fujii, T; Morimoto, H; Senoh, H	1
Braquet, P; Hosford, D; Mencia-Huerta, JM	1
Bekemeier, H; Sänze, JU	1
Bertrand, C; Daffonchio, L; Geppetti, P; Huber, O; Nadel, JA; Omini, C; Yamawaki, I	1
Capen, CC; Horton, JE; McCauley, LK; Nohutcu, RM; Rosol, TJ	1
McDonald, DM; Sulakvelidze, I	1
Kamei, C; Nakamura, S; Tasaka, K	1
Chandel, B; Deshpande, Y; Kaminski, DL; Longo, WE; Niehoff, M; Polities, G; Robinson, S; Vernava, AM	1
Greenlees, C; Medhurst, AD; Parsons, AA; Smith, SJ	1
Bowden, JJ; McDonald, DM; Sulakvelidze, I	1
Woodhead, CJ	1
Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K	1
Inoue, H; Koshihara, Y; Nagata, N	1
Levi-Schaffer, F; Slavin, S; Vourka-Karussis, U	1
Bendele, AM; Cockerham, SL; Silbaugh, SA; Stengel, PW	1
Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF	1
Betts, WH; McLennan, G; Scicchitano, R; Wozniak, A	1
Bertrand, C; Desai, MC; Geppetti, P; Nadel, JA; Piedimonte, G; Snider, RM	1
Iwamoto, I; Tomioka, H; Tomoe, S; Yoshida, S	1
Iwamoto, I; Tomoe, S; Yoshida, S	1
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M	1
Fan, TP; Gresham, GA; Guard, S; Hu, DE; Watling, KJ	1
Baskin, SI; Lempka, JC; Nealley, EW	1
Calixto, JB; Cechinel Filho, V; Paulino, N; Pizzolatti, MG; Yunes, RA	1
Jouët, P; Sarna, SK	1
Bell, JG; Sargent, JR; Tocher, DR	1
Chen, IS; Ishii, H; Ishikawa, T; Ko, FN; Kuo, HP; Lin, CH; Teng, CM	1
El-Shazly, AE; Eura, M; Ishikawa, T; Masuyama, K	1
Howarth, PH	1
Alger, LE; Carson, SS; Garland, A; Leff, AR; McAllister, K; Necheles, J; Neeley, SP; Solway, J; White, SR	1
Akuta, K; Manabe, H; Ohmori, K; Okamura, K	1
Nagai, A; Takeda, Y; Tamaoki, J; Yamawaki, I	1
Koyama, S; Kubo, K; Okubo, Y; Sato, E; Sekiguchi, M	1
Held, HD; Martin, C; Uhlig, S	1
Baluk, P; Gómez, AD; Hashizume, H; Kwan, ML; McDonald, DM	1
Steer, ML	1
Bhatia, M; Neoptolemos, JP; Slavin, J	1
Apostoliti, F; Breschi, MC; Martinotti, E; Nieri, P	1
Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC	1
Buckley, A; Chilvers, ER; Haslett, C; MacKinnon, AC; Rossi, AG; Sethi, T	1
Amemiya, T; Fujimura, M; Ishiura, Y; Kurashima, K; Myou, S; Nobata, K; Nonomura, A	1
Behar, J; Biancani, P; Cao, W; Cheng, L; de la Monte, S; Harnett, KM; Hong, J; Ma, J; Tong, M	1
Chang, W; Chen, J; Hoyle, GW; Schlueter, CF	1
Altomare, A; Behar, J; Biancani, P; Harnett, KM; Ma, J; Rieder, F	1
Akbarshahi, H; Andersson, R; Rosendahl, AH; Westergren-Thorsson, G	1
Alevizos, M; Kalogeromitros, D; Karagkouni, A; Makris, M; Sismanopoulos, N; Theoharides, TC; Vasiadi, M	1

Reviews

6 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and substance p

Article	Year
[Mediators and neuromediators in asthma]. Presse medicale (Paris, France : 1983), 1992, Feb-15, Volume: 21, Issue:6 Topics: Asthma; Atrial Natriuretic Factor; Cytokines; Histamine; Humans; Leukotrienes; Parasympathetic Nervous System; Platelet Activating Factor; Prostaglandins; Substance P; Sympathetic Nervous System; Sympathomimetics; Vasoactive Intestinal Peptide	1992
Acute and long-term pulmonary effects of platelet-activating factor. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1989, Volume: 19, Issue:2 Topics: Anaphylaxis; Animals; Bronchial Spasm; Humans; Leukotrienes; Lung; Platelet Activating Factor; Prostaglandins; Substance P	1989
Neuropeptides in nasal mucosa. Clinical otolaryngology and allied sciences, 1994, Volume: 19, Issue:4 Topics: Bradykinin; Calcitonin Gene-Related Peptide; Cytokines; Eicosanoids; Histamine H1 Antagonists; Humans; Nasal Mucosa; Nasal Polyps; Neurokinin A; Neuropeptide Y; Platelet Activating Factor; Receptors, Calcitonin Gene-Related Peptide; Rhinitis; Substance P; Vasoactive Intestinal Peptide	1994
Mediators of nasal blockage in allergic rhinitis. Allergy, 1997, Volume: 52, Issue:40 Suppl Topics: Histamine; Humans; Kinins; Leukotrienes; Nasal Obstruction; Platelet Activating Factor; Prostaglandin D2; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Substance P	1997
Inflammatory mediators as therapeutic targets in acute pancreatitis. Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:4 Topics: Acute Disease; Chemokines; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-10; Pancreatitis; Platelet Activating Factor; Substance P; Tumor Necrosis Factor-alpha	2001
Acute lung injury in acute pancreatitis--awaiting the big leap. Respiratory medicine, 2012, Volume: 106, Issue:9 Topics: Acute Disease; Acute Lung Injury; Chemokines; Cytokines; Humans; Kupffer Cells; Macrophages; Mast Cells; Matrix Metalloproteinases; Neutrophils; NF-kappa B; Pancreatitis; Platelet Activating Factor; Poly(ADP-ribose) Polymerases; Substance P	2012

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and substance p

Article	Year
Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1995, Volume: 75, Issue:2 Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; Female; Histamine; Humans; Male; Platelet Activating Factor; Procaterol; Skin; Skin Tests; Substance P	1995

Article

Year

Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1995, Volume: 75, Issue:2

Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; Female; Histamine; Humans; Male; Platelet Activating Factor; Procaterol; Skin; Skin Tests; Substance P

1995

Other Studies

58 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and substance p

Article	Year
Neuropeptides modulate human eosinophil chemotaxis. Journal of immunology (Baltimore, Md. : 1950), 1992, Nov-15, Volume: 149, Issue:10 Topics: Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Neuropeptides; Peptide Fragments; Platelet Activating Factor; Protease Inhibitors; Receptors, Calcitonin; Receptors, Cell Surface; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P	1992
Ro 19-3704 directly inhibits immunoglobulin E-dependent mediator release by a mechanism independent of its platelet-activating factor antagonist properties. European journal of pharmacology, 1990, Feb-13, Volume: 176, Issue:3 Topics: Animals; Azepines; Diterpenes; Ginkgolides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Inositol Phosphates; L-Lactate Dehydrogenase; Lactones; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Substance P; Synovial Fluid; Thiazoles; Triazines; Triazoles; Tumor Cells, Cultured	1990
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells. Agents and actions, 1990, Volume: 30, Issue:1-2 Topics: Animals; Ascitic Fluid; Calcium; Cyclohexanones; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Inbred Strains; Substance P; Tetradecanoylphorbol Acetate; Thiazoles	1990
Platelet activating factor does not release histamine from human dispersed cutaneous mast cells. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:4 Topics: Antibodies, Anti-Idiotypic; Biomarkers, Tumor; Blood Platelets; Calcimycin; Calcium; Cells, Cultured; Child; Child, Preschool; Energy Metabolism; Histamine; Histamine Release; Humans; Infant; Leukocytes; Lymphokines; Male; Mast Cells; Platelet Activating Factor; Skin; Substance P; Tumor Protein, Translationally-Controlled 1	1990
[Airway hyperresponsiveness and mucus secretion]. Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:10 Topics: Asthma; Autonomic Nervous System; Bronchi; Exocrine Glands; Humans; Mucus; Platelet Activating Factor; Substance P	1990
Priming effects of mammalian tachykinins on human neutrophils. Life sciences, 1991, Volume: 48, Issue:2 Topics: Dose-Response Relationship, Drug; Humans; Neurokinin A; Neurokinin B; Neutrophils; Platelet Activating Factor; Stimulation, Chemical; Substance P; Superoxides; Tachykinins	1991
Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer. Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1 Topics: Animals; Azepines; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Hydroxyzine; In Vitro Techniques; Ketotifen; Leukotriene B4; Male; Mast Cells; Pepsin A; Peptide Fragments; Platelet Activating Factor; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; SRS-A; Substance P; Triazoles	1991
Neutral endopeptidase and kininase II mediate glucocorticoid inhibition of neurogenic inflammation in the rat trachea. The Journal of clinical investigation, 1991, Volume: 88, Issue:1 Topics: Animals; Capillary Permeability; Captopril; Dexamethasone; Endopeptidases; Glycopeptides; Male; Peptidyl-Dipeptidase A; Platelet Activating Factor; Rats; Rats, Inbred Strains; Substance P; Trachea	1991
Eosinophil activation on biologic surfaces. Production of O2- in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells. Journal of immunology (Baltimore, Md. : 1950), 1991, Jul-15, Volume: 147, Issue:2 Topics: Endothelium, Vascular; Eosinophils; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	1991
Neutrophil chemotactic activity of PAF, histamine and neuromediators in bronchial asthma. Journal of lipid mediators, 1991, Volume: 4, Issue:3 Topics: Adolescent; Adult; Asthma; Chemotaxis, Leukocyte; Histamine; Humans; Middle Aged; Neuropeptides; Neutrophils; Platelet Activating Factor; Somatostatin; Substance P; Vasoactive Intestinal Peptide	1991
Release of tachykinins by histamine, methacholine, PAF, LTD4, and substance P from guinea pig lungs. The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1 Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Kinetics; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Platelet Activating Factor; SRS-A; Substance P; Tachykinins	1991
[Regulation of thrombocyte stimulating and other activities of thrombin by modulators of the recognition site]. Vestnik Akademii meditsinskikh nauk SSSR, 1991, Issue:10 Topics: Endothelium, Vascular; Humans; In Vitro Techniques; Models, Biological; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein C; Receptors, Cell Surface; Receptors, Thrombin; Substance P; Thrombin; Thymosin	1991
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. British journal of pharmacology, 1985, Volume: 86, Issue:4 Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5; Complement C5a, des-Arginine; Dinoprostone; Drug Synergism; Edema; Histamine; Inflammation; Injections, Intradermal; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins E; Rabbits; Rats; Rats, Inbred Lew; Skin; Species Specificity; Substance P	1985
The effect of vasoactive intestinal peptide and calcitonin gene-related peptide on peptidoleukotriene release from platelet activating factor stimulated rat lungs and ionophore stimulated guinea pig lungs. Biochemistry international, 1986, Volume: 13, Issue:6 Topics: Acetylcholine; Animals; beta-Endorphin; Calcimycin; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Endorphins; Guinea Pigs; In Vitro Techniques; Lung; Male; Neuropeptides; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Substance P; Vasoactive Intestinal Peptide	1986
Characterization of substance P contractile activity on isolated guinea pig lung tissues. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Neurokinin A; Neuropeptides; Platelet Activating Factor; Prostaglandins; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Trachea	1987
Leukotriene B4, platelet-activating factor and substance P as mediators of acute inflammation. Pathology and immunopathology research, 1987, Volume: 6, Issue:3 Topics: Acute Disease; Animals; Cheek; Cricetinae; Inflammation; Leukotriene B4; Mesocricetus; Mouth Mucosa; Muscles; Platelet Activating Factor; Rabbits; Substance P	1987
Pulmonary responses to bronchoconstrictor agonists in the mouse. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6 Topics: Animals; Histamine; Indomethacin; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Mice; Mice, Inbred C57BL; Norepinephrine; Platelet Activating Factor; Plethysmography; Propranolol; Prostaglandins; Reference Values; Serotonin; SRS-A; Substance P	1988
The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle. European journal of pharmacology, 1989, Jan-02, Volume: 159, Issue:1 Topics: Acetylcholine; Animals; Calcium; Diacylglycerol Kinase; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Substance P; Thiazoles	1989
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation. Japanese journal of pharmacology, 1989, Volume: 49, Issue:3 Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea	1989
Vasodepression ex vivo after administration of inflammatory mediators in vivo in the rat. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Alprostadil; Animals; Biological Factors; Bradykinin; Endotoxins; Epoprostenol; Escherichia coli; Female; Histamine; Inflammation; Norepinephrine; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Serotonin; SRS-A; Substance P; Vasoconstriction	1989
Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea. European journal of pharmacology, 1993, Oct-12, Volume: 243, Issue:1 Topics: Animals; Antitussive Agents; Blood Pressure; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Heart Rate; In Vitro Techniques; Muscle Contraction; Peripheral Nervous System; Platelet Activating Factor; Propylene Glycols; Rats; Rats, Inbred F344; Substance P; Trachea; Urinary Bladder	1993
Effects of hormones and cytokines on stimulation of adenylate cyclase and intracellular calcium concentration in human and canine periodontal-ligament fibroblasts. Archives of oral biology, 1993, Volume: 38, Issue:10 Topics: Adenylyl Cyclases; Adult; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Calcium; Carrier Proteins; Cells, Cultured; Cyclic AMP; Cyclic AMP Receptor Protein; Cytokines; Dinoprostone; Dogs; Fibroblasts; Hormones; Humans; Interleukin-1; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Periodontal Ligament; Platelet Activating Factor; Proteins; Stimulation, Chemical; Substance P; Transforming Growth Factor beta	1993
Anti-edema action of formoterol in rat trachea does not depend on capsaicin-sensitive sensory nerves. American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Afferent Pathways; Animals; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Endothelium, Vascular; Ethanolamines; Formoterol Fumarate; Injections, Intravenous; Male; Platelet Activating Factor; Premedication; Rats; Rats, Inbred F344; Substance P; Trachea; Tracheal Diseases	1994
Effects of antiallergic agents including levocabastine on experimental rhinitis in rats. Arzneimittel-Forschung, 1994, Volume: 44, Issue:3 Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Histamine; Histamine H1 Antagonists; Ketotifen; Male; Nasal Mucosa; Piperidines; Platelet Activating Factor; Rats; Rats, Wistar; Rhinitis; Substance P	1994
Effect of platelet-activating factor and its antagonists on colonic dysmotility and tissue levels of colonic neuropeptides. European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1 Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide	1994
Nitric oxide synthase inhibitors 7- and 6-nitroindazole relax smooth muscle in vitro. European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1 Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide	1994
Inhibition of neutrophil and eosinophil adhesion to venules of rat trachea by beta 2-adrenergic agonist formoterol. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:1 Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Cell Adhesion; Eosinophils; Ethanolamines; Formoterol Fumarate; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Propanolamines; Rats; Rats, Inbred F344; Regional Blood Flow; Substance P; Trachea; Venules	1994
Inhibition by actinomycin D of neurogenic mouse ear oedema. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:3 Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide	1995
Investigations on the role of inflammatory and anti-inflammatory agents on the treatment of murine B cell leukemia by recombinant human interleukin-2. Experimental hematology, 1993, Volume: 21, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Dinoprostone; Freund's Adjuvant; Histamine; Inflammation; Interleukin-2; Leukemia, B-Cell; Lipopolysaccharides; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Recombinant Proteins; Substance P	1993
Inhaled A23187 produces a preferential sensitization to substance P. The American review of respiratory disease, 1993, Volume: 147, Issue:1 Topics: Animals; Bronchial Provocation Tests; Bronchoconstriction; Calcimycin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Lung Volume Measurements; Male; Neprilysin; Platelet Activating Factor; SRS-A; Substance P; Thiorphan	1993
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo. British journal of pharmacology, 1993, Volume: 108, Issue:3 Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve	1993
Activation of human neutrophils by tachykinins: effect on formyl-methionyl-leucyl-phenylalanine- and platelet-activating factor-stimulated superoxide anion production and antibody-dependent cell-mediated cytotoxicity. Immunology, 1993, Volume: 78, Issue:4 Topics: Antibody-Dependent Cell Cytotoxicity; Cells, Cultured; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Substance P; Superoxides; Tachykinins	1993
A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1 Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertonic Solutions; Neurokinin A; Neurons, Afferent; Piperidines; Platelet Activating Factor; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium Chloride; Stimulation, Chemical; Substance P; Trachea; Tracheal Diseases	1993
Leukotriene B4 mediates substance P-induced granulocyte infiltration into mouse skin. Comparison with antigen-induced granulocyte infiltration. Journal of immunology (Baltimore, Md. : 1950), 1993, Aug-15, Volume: 151, Issue:4 Topics: Animals; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophils; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin Physiological Phenomena; Substance P	1993
Role of leukotriene B4 in substance P-induced granulocyte infiltration in mouse skin. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Granulocytes; Leukotriene B4; Mast Cells; Mice; Mice, Inbred BALB C; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin; Skin Physiological Phenomena; Substance P	1993
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter	1993
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists. British journal of pharmacology, 1993, Volume: 110, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Interleukin-1; Male; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Receptors, Interleukin-1; Receptors, Neurokinin-1; Regional Blood Flow; Substance P; Xenon Radioisotopes	1993
The effects of EDRF/NO releasers or calcium ionophore A23187 on cyanide toxicity in mice. Toxicology and applied pharmacology, 1996, Volume: 139, Issue:2 Topics: Animals; Bradykinin; Calcimycin; Carbachol; Cyanides; Hydralazine; Ionophores; Lethal Dose 50; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Seizures; Substance P; Survival Rate	1996
Mechanisms involved in the contractile responses induced by the hydroalcoholic extract of Phyllanthus urinaria on the guinea pig isolated trachea: evidence for participation of tachykinins and influx of extracellular Ca2+ sensitive to ruthenium red. General pharmacology, 1996, Volume: 27, Issue:5 Topics: Animals; Calcium; Calcium Channel Blockers; Extracellular Space; Female; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Plant Extracts; Plants, Medicinal; Platelet Activating Factor; Prostaglandin Antagonists; Receptors, Neurokinin-2; Ruthenium Red; Substance P; Tachykinins; Trachea	1996
Platelet-activating factor (PAF) stimulates giant migrating contractions during ileal inflammation. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1 Topics: Animals; Calcium; Dogs; Female; Ileitis; Ileum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Neostigmine; Platelet Activating Factor; Substance P	1996
Production of eicosanoids derived from 20:4n-6 and 20:5n-3 in primary cultures of turbot (Scophthalmus maximus) brain astrocytes in response to platelet activating factor, substance P and interleukin-1 beta. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1996, Volume: 115, Issue:2 Topics: Animals; Astrocytes; Brain; Cattle; Cells, Cultured; Culture Media; Eicosanoids; Fatty Acids, Unsaturated; Flatfishes; Interleukin-1; Leukotrienes; Platelet Activating Factor; Prostaglandins; Substance P	1996
The effect of the selective PAF antagonist CIS-19 on PAF- and antigen-induced bronchoconstriction, microvascular leakage and bronchial hyperreactivity in guinea-pigs. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2 Topics: Airway Resistance; Animals; Antigens; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Guinea Pigs; Histamine; Male; Methacholine Chloride; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Hypersensitivity; Substance P; Tetrahydronaphthalenes	1997
Immunoregulatory effect of substance P in human eosinophil migratory function. Immunological investigations, 1996, Volume: 25, Issue:3 Topics: Adjuvants, Immunologic; Chemotaxis, Leukocyte; Dipeptides; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Indoles; Inflammation; Interleukin-5; Male; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Recombinant Proteins; Substance P	1996
Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Animals; Animals, Newborn; Asthma; Capsaicin; Cells, Cultured; Coculture Techniques; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Eosinophils; Ganglia, Spinal; Humans; Myelin Basic Protein; N-Formylmethionine Leucyl-Phenylalanine; Neurons; Platelet Activating Factor; Polylysine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic, Seasonal; Substance P; Tissue Extracts	1997
KF19514, a phosphodieterase 4 and 1 inhibitor, inhibits PAF-induced lung inflammatory responses by inhaled administration in guinea pigs. International archives of allergy and immunology, 1997, Volume: 114, Issue:4 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Electric Stimulation; Eosinophils; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Naphthyridines; Neurokinin A; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Activating Factor; Pyrrolidinones; Respiratory Therapy; Rolipram; Substance P	1997
Inhaled cromoglycate reduces airway neurogenic inflammation via tachykinin antagonism. Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:3 Topics: Administration, Inhalation; Animals; Anti-Asthmatic Agents; Capillary Permeability; Cromolyn Sodium; Dose-Response Relationship, Drug; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Specific Pathogen-Free Organisms; Substance P; Tachykinins; Trachea	1997
Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. The American journal of physiology, 1998, Volume: 274, Issue:6 Topics: Acetylcholine; Animals; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cholinergic Antagonists; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukins; Leukotriene B4; Leukotriene C4; Leukotriene D4; Macrophages, Alveolar; Monocytes; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Substance P	1998
Characterization of airway and vascular responses in murine lungs. British journal of pharmacology, 1999, Volume: 126, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Bombesin; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Endothelin-1; Female; Histidine; In Vitro Techniques; Leukotriene C4; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Perfusion; Platelet Activating Factor; Serotonin; Substance P; Vasoconstriction; Vasoconstrictor Agents	1999
Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:2 Topics: Albuterol; Animals; Bronchodilator Agents; Capillary Permeability; Chronic Disease; Dose-Response Relationship, Drug; Drug Hypersensitivity; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indoles; Male; Mycoplasma Infections; Organ Size; Organometallic Compounds; Platelet Activating Factor; Rats; Rats, Inbred F344; Rats, Wistar; Salmeterol Xinafoate; Serotonin; Species Specificity; Specific Pathogen-Free Organisms; Substance P; Trachea	2001
Relationship between pancreatitis and lung diseases. Respiration physiology, 2001, Volume: 128, Issue:1 Topics: Acute Disease; Animals; Complement C5a; Disease Models, Animal; Female; Humans; Intercellular Adhesion Molecule-1; Lung Diseases; Mice; Mice, Knockout; Neutrophils; Pancreatitis; Platelet Activating Factor; Rats; Receptors, CCR1; Receptors, Chemokine; Substance P	2001
Protective effect of silymarin in antigen challenge- and histamine-induced bronchoconstriction in in vivo guinea-pigs. European journal of pharmacology, 2002, Feb-15, Volume: 437, Issue:1-2 Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Protective Agents; Silymarin; Substance P; Time Factors	2002
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2 Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors	2002
Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents. Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-01, Volume: 169, Issue:11 Topics: Adult; Apoptosis; Calcium Signaling; Cell Polarity; Cell Size; Chromones; Enzyme Activation; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Recombinant Proteins; Respiratory Burst; Signal Transduction; Sphingosine; Substance P; Superoxides; Tumor Necrosis Factor-alpha	2002
Airway eosinophil accumulation on sensory neuropeptide release in a guinea pig model of distilled-water-induced bronchoconstriction. Journal of investigational allergology & clinical immunology, 2003, Volume: 13, Issue:2 Topics: Aerosols; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Disease Models, Animal; Eosinophils; Guinea Pigs; Immunization, Passive; Male; Methacholine Chloride; Piperidines; Platelet Activating Factor; Quinuclidines; Substance P; Water	2003
HCl-activated neural and epithelial vanilloid receptors (TRPV1) in cat esophageal mucosa. American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:1 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Diterpenes; Electric Stimulation; Epithelial Cells; Esophagus; Hydrochloric Acid; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Stimulation, Chemical; Submucous Plexus; Substance P; Tetrodotoxin; TRPV Cation Channels	2009
Common pathways for activation of proinflammatory gene expression by G protein-coupled receptors in primary lung epithelial and endothelial cells. Experimental lung research, 2009, Volume: 35, Issue:4 Topics: Animals; Chemokine CXCL1; Endothelial Cells; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Lung; Male; Microvessels; Platelet Activating Factor; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Substance P	2009
ATP: a mediator for HCl-induced TRPV1 activation in esophageal mucosa. American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:6 Topics: Acetyltransferases; Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcitonin Gene-Related Peptide; Cell Line; Esophagus; Humans; Hydrochloric Acid; Mucous Membrane; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Rabbits; Real-Time Polymerase Chain Reaction; Receptors, Purinergic; Substance P; Suramin; TRPV Cation Channels	2011
Rupatadine inhibits inflammatory mediator release from human laboratory of allergic diseases 2 cultured mast cells stimulated by platelet-activating factor. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 111, Issue:6 Topics: Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cyproheptadine; Histamine; Humans; Interleukin-8; Mast Cells; Platelet Activating Factor; Substance P; Tumor Necrosis Factor-alpha	2013