1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with sphingosine in 35 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (sphingosine) | Trials (sphingosine) | Recent Studies (post-2010) (sphingosine) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 8,325 | 117 | 3,459 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | sphingosine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 6.3125 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | 0.098 | |
| Sphingosine kinase 2 | Homo sapiens (human) | 1.56 | |
| Sphingosine kinase 1 | Homo sapiens (human) | 3.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 15 (42.86) | 18.2507 |
| 2000's | 10 (28.57) | 29.6817 |
| 2010's | 4 (11.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Fujii, T; Hashizume, T; Sato, T | 1 |
| Chiang, TM; Ong, RC; Yoo, TJ | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Jacobson, D; O'Flaherty, JT | 1 |
| Arese, P; Bussolino, F; Fischer, E; Kazatchkine, MD; Turrini, F | 1 |
| McIntyre, TM; Nelson, P; Parker, CJ; Prescott, SM; Stevens, DL; Whatley, RE; Zimmerman, GA | 1 |
| Benveniste, J; Bessou, G; Bossant, MJ; Joly, F; Leyravaud, S; Ninio, E | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| Bell, RM; Greenberg, CS; Hannun, YA | 1 |
| Kondo, Y; Okajima, F | 1 |
| Kulaev, IS; Kulakovskaia, TV; Lichko, LP | 1 |
| Larivée, P; Levine, SJ; Logun, C; Martinez, A; Shelhamer, JH; Wu, T | 1 |
| Akkerman, JW; Burgers, JA | 1 |
| Henry, PD; Kerns, SA; Kugiyama, K; Mangin, EL; Nguy, JH | 1 |
| Lee, TC; Malone, B; Ou, MC; Shinozaki, K; Snyder, F | 1 |
| Jarvis, WD; Spangelo, BL | 1 |
| Lee, T | 1 |
| Igarashi, Y | 1 |
| Karasawa, K; Lee, T; Qiu, X | 1 |
| Barros, FS; Dutra, PM; Lopes, AH; Meyer-Fernandes, JR; Rodrigues, CO; Souto-Padrón, T | 1 |
| Dutra, PM; Lopes, AH; Pereira, AF; Rosa , MS; Vieira, RB | 1 |
| Buckley, A; Chilvers, ER; Haslett, C; MacKinnon, AC; Rossi, AG; Sethi, T | 1 |
| Bernatchez, PN; Neagoe, PE; Rollin, S; Sirois, MG; Tremblay, F | 1 |
| Barnes, PJ | 1 |
| He, P; Minnear, FL; Zhu, L | 1 |
| Damaj, BB; Jin, Y; Maghazachi, AA | 1 |
| Deussen, A; Pexa, A | 1 |
| Barthomeuf, C; Béliveau, R; Blanchette, M; Boivin, D; Gingras, D; Lamy, S | 1 |
| Baes, M; Denizot, Y; Van Overloop, H; Van Veldhoven, PP | 1 |
| Camerer, E; Cornelissen, I; Coughlin, SR; Duong, DN; Palmer, D; Pappu, R; Pham, TH; Regard, JB; Srinivasan, Y; Wong, JS | 1 |
| Incorvaia, C; Incorvaia, S; Mauro, M; Pravettoni, V; Riario-Sforza, GG | 1 |
| Adamson, RH; Altangerel, A; Clark, JF; Curry, FR; Sarai, RK; Thirkill, TL | 1 |
| Babendreyer, A; Kuebler, WM; Uhlig, S; Waade, J; Wittenberg, C; Yang, Y | 1 |
| Kulinski, JM; Muñoz-Cano, R; Olivera, A | 1 |
4 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and sphingosine
| Article | Year |
|---|---|
[Physiology of sphingosine 1-phosphate: regulation of cell motility and platelet function].
Topics: Animals; Blood Platelets; Cell Division; Cell Movement; Humans; Lysophospholipids; Microfilament Proteins; Platelet Activating Factor; Second Messenger Systems; Sphingosine | 1997 |
Anaphylaxis: an update on its understanding and management.
Topics: Anaphylaxis; Animals; Food Hypersensitivity; Humans; Immunotherapy; Lysophospholipids; Patents as Topic; Platelet Activating Factor; Signal Transduction; Sphingosine | 2010 |
Differential regulation of lung endothelial permeability in vitro and in situ.
Topics: Animals; Capillary Permeability; Endothelial Cells; Humans; Lung; Lysophospholipids; Platelet Activating Factor; Pulmonary Edema; rho-Associated Kinases; Signal Transduction; Sphingosine; Thrombin | 2014 |
Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function.
Topics: Animals; Eicosanoids; Humans; Hypersensitivity; Lysophospholipids; Mast Cells; Platelet Activating Factor; Sphingosine | 2016 |
31 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and sphingosine
| Article | Year |
|---|---|
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcium; Cell Membrane; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Piperazines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Rabbits; Sphingosine; Staurosporine; Thrombin; Type C Phospholipases | 1992 |
Activation mechanisms of platelet-activating factor in U937 cells: possible involvement of protein kinase C.
Topics: Diglycerides; Down-Regulation; Humans; In Vitro Techniques; Macrophages; Molecular Weight; Phorbol Esters; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sphingosine; Tumor Cells, Cultured | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Protein kinase C blockers and neutrophil receptors for leukotriene B4.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Receptors, Leukotriene B4; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thermodynamics | 1989 |
Platelet-activating factor enhances complement-dependent phagocytosis of diamide-treated erythrocytes by human monocytes through activation of protein kinase C and phosphorylation of complement receptor type one (CR1).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Azo Compounds; Cell Adhesion; Complement System Proteins; Diamide; Enzyme Activation; Erythrocytes; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Monocytes; Palmitoylcarnitine; Phagocytosis; Phosphorylation; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Complement; Sphingosine; Staurosporine; Structure-Activity Relationship | 1989 |
The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C.
Topics: Adenine Nucleotides; Animals; Bacterial Toxins; Bradykinin; Calcium; Cations, Divalent; Cattle; Cytoplasm; Endothelium; Hemolysin Proteins; In Vitro Techniques; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Biosynthesis of paf-acether. X. Phorbol myristate acetate-induced paf-acether biosynthesis and acetyltransferase activation in human neutrophils.
Topics: Acetyltransferases; Chromatography, Gas; Diglycerides; Enzyme Activation; Humans; Neutrophils; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.
Topics: Amines; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Palmitoylcarnitine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1987 |
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Diglycerides; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Sphingosine; Thrombin | 1987 |
Pertussis toxin inhibits phospholipase C activation and Ca2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL60 leukemia cells. Implications of GTP-binding protein-coupled receptors for lysosphingolipids.
Topics: Calcium; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; HL-60 Cells; Humans; Kinetics; Lysophospholipids; Neutrophils; Pertussis Toxin; Phosphorylcholine; Platelet Activating Factor; Psychosine; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingomyelin Phosphodiesterase; Sphingosine; Type C Phospholipases; Uridine Triphosphate; Virulence Factors, Bordetella | 1995 |
[The effect of PAF, sphingosine and heparin on certain phosphohydrolase and transport activity of yeast vacuoles].
Topics: Adenosine Triphosphatases; Biological Transport; Heparin; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Saccharomyces cerevisiae; Sphingosine; Vacuoles | 1994 |
Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cats; Cell Fractionation; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Enzyme Activation; Epithelium; Isoenzymes; Isoquinolines; Kinetics; Molecular Weight; Mucins; Piperazines; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Regulation of the receptor for platelet-activating factor on human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkaloids; Antimycin A; Blood Platelets; Calmodulin; Cyclic AMP; Deoxyglucose; Energy Metabolism; Humans; Phosphoproteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Effects of lysolipids and oxidatively modified low density lipoprotein on endothelium-dependent relaxation of rabbit aorta.
Topics: Animals; Aorta; Arteriosclerosis; Endothelium, Vascular; Lipoproteins, LDL; Lysophosphatidylcholines; Lysophospholipase; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rabbits; Sphingosine; Vasodilation | 1993 |
Biosynthesis of N-acetylsphingosine by platelet-activating factor: sphingosine CoA-independent transacetylase in HL-60 cels.
Topics: Acetyltransferases; Binding, Competitive; Chromatography, Thin Layer; Diethyl Pyrocarbonate; Enzyme Inhibitors; Ethylmaleimide; HL-60 Cells; Humans; Lung; Platelet Activating Factor; Sphingosine; Stereoisomerism; Substrate Specificity | 1996 |
Lysophosphatidylcholine stimulates interleukin-6 release from rat anterior pituitary cells in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Enzyme Inhibitors; Interleukin-1; Interleukin-6; Lysophosphatidylcholines; Male; Phenanthridines; Phosphorylcholine; Pituitary Gland, Anterior; Platelet Activating Factor; Prolactin; Protein Kinase C; Rats; Rats, Inbred Strains; Sphingosine | 1996 |
Acetylation of sphingosine by PAF-dependent transacetylase.
Topics: Acetylation; Acetyltransferases; HL-60 Cells; Hot Temperature; Humans; Hydrogen-Ion Concentration; Platelet Activating Factor; Sphingosine; Subcellular Fractions | 1996 |
Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide.
Topics: Acetyltransferases; Animals; Cell Membrane; Ceramides; Chromatography, Affinity; Enzyme Inhibitors; Ethanolamines; Kidney; Kinetics; Microsomes; Mitochondria; Plasmalogens; Platelet Activating Factor; Polysorbates; Rats; Sphingosine; Substrate Specificity | 1999 |
Platelet-activating factor induction of secreted phosphatase activity in Trypanosoma cruzi.
Topics: Animals; Azepines; Culture Media, Conditioned; Phosphoprotein Phosphatases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Triazoles; Trypanosoma cruzi | 1999 |
Platelet-activating factor (PAF) modulates peritoneal mouse macrophage infection by Leishmania amazonensis.
Topics: Animals; Azepines; Female; Leishmania; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Triazoles | 2001 |
Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents.
Topics: Adult; Apoptosis; Calcium Signaling; Cell Polarity; Cell Size; Chromones; Enzyme Activation; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Recombinant Proteins; Respiratory Burst; Signal Transduction; Sphingosine; Substance P; Superoxides; Tumor Necrosis Factor-alpha | 2002 |
Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: role in cellular migration.
Topics: Animals; Aorta; Cattle; Cell Movement; Cells, Cultured; Endothelial Cells; Enzyme Activation; Humans; Lysophospholipids; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; Sphingosine; Vascular Endothelial Growth Factor A | 2003 |
Ceramide lances the lungs.
Topics: Animals; Ceramides; Humans; Inflammation; Lung; Lysophospholipids; Mice; Platelet Activating Factor; Respiratory Distress Syndrome; Sphingomyelin Phosphodiesterase; Sphingosine; Tumor Necrosis Factor-alpha | 2004 |
Sphingosine 1-phosphate prevents platelet-activating factor-induced increase in hydraulic conductivity in rat mesenteric venules: pertussis toxin sensitive.
Topics: Animals; Body Water; Capillary Permeability; Female; Lysophospholipids; Mesentery; Pertussis Toxin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sphingosine; Venules | 2005 |
Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor.
Topics: Cell Cycle Proteins; Chemotaxis; Diterpenes; Fibrinolytic Agents; Flow Cytometry; Ginkgolides; Humans; Interferon-alpha; Interleukins; Killer Cells, Natural; Lactones; Lymphocyte Activation; Lysophosphatidylcholines; Pertussis Toxin; Phosphorylcholine; Platelet Activating Factor; Receptors, G-Protein-Coupled; Receptors, IgG; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine | 2005 |
Modulation of ecto-5'-nucleotidase by phospholipids in human umbilical vein endothelial cells (HUVEC).
Topics: 5'-Nucleotidase; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lysophosphatidylcholines; Molecular Structure; Phospholipids; Platelet Activating Factor; Sphingosine; Umbilical Veins | 2005 |
Inhibition of sphingosine-1-phosphate- and vascular endothelial growth factor-induced endothelial cell chemotaxis by red grape skin polyphenols correlates with a decrease in early platelet-activating factor synthesis.
Topics: Animals; Aorta; Cattle; Cell Movement; Cells, Cultured; Chemotaxis; Endothelium, Vascular; Fibrosarcoma; Flavonoids; Glioblastoma; Humans; Lysophospholipids; Medulloblastoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; Neovascularization, Physiologic; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polyphenols; Receptors, G-Protein-Coupled; Sphingosine; Vascular Endothelial Growth Factor A; Vitis | 2006 |
On the presence of C2-ceramide in mammalian tissues: possible relationship to etherphospholipids and phosphorylation by ceramide kinase.
Topics: Animals; Ceramides; CHO Cells; Cricetinae; Cricetulus; Mice; Phospholipid Ethers; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Sphingosine | 2007 |
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.
Topics: Animals; Capillary Permeability; Erythrocyte Transfusion; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Inflammation; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Platelet Activating Factor; Receptors, Lysosphingolipid; Sphingosine | 2009 |
Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels.
Topics: Acute Disease; Animals; Antigens, CD; Bradykinin; Cadherins; Capillary Permeability; Cell Adhesion; Cells, Cultured; Cortactin; Endothelial Cells; Fluorescent Antibody Technique; Humans; Inflammation; Lysophospholipids; Male; Membrane Proteins; Mesentery; Microscopy, Confocal; Occludin; Platelet Activating Factor; rac GTP-Binding Proteins; Rats; Sphingosine; Time Factors; Venules | 2010 |