Compounds > 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and sb 203580

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with sb 203580 in 12 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010) (sb 203580)
9,1561875523,48941,137

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)sb 203580 (IC50)
Citron Rho-interacting kinaseHomo sapiens (human)1
Cyclin-G-associated kinaseHomo sapiens (human)0.4133
Mitogen-activated protein kinase 13Homo sapiens (human)0.2329
Mitogen-activated protein kinase 2Pneumocystis carinii0.105
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)1.0359
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.7575
Cytochrome P450 1A2Homo sapiens (human)2
Tyrosine-protein kinase LckHomo sapiens (human)3.45
Neutrophil elastaseHomo sapiens (human)0.025
Cytochrome P450 3A4Homo sapiens (human)0.062
Cytochrome P450 2D6Homo sapiens (human)2
TyrosinaseMus musculus (house mouse)0.034
Cholesteryl ester transfer proteinHomo sapiens (human)0.04
Cytochrome P450 2C9 Homo sapiens (human)1
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)5
Serine/threonine-protein kinase B-rafHomo sapiens (human)1
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.36
Prostaglandin G/H synthase 1Homo sapiens (human)2
Thromboxane-A synthase Homo sapiens (human)0.494
Adenosine receptor A2aHomo sapiens (human)6.068
Ephrin type-B receptor 2Homo sapiens (human)7.8
Adenosine receptor A1Homo sapiens (human)2.95
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.01
Delta-type opioid receptorMus musculus (house mouse)0.02
Cytochrome P450 2C19Homo sapiens (human)0.8
TGF-beta receptor type-1Homo sapiens (human)6
Mitogen-activated protein kinase 9Homo sapiens (human)0.9517
Mitogen-activated protein kinase 14 Mus musculus (house mouse)0.056
Casein kinase I isoform deltaHomo sapiens (human)0.4147
Casein kinase I isoform epsilonHomo sapiens (human)1
Mitogen-activated protein kinase 12Homo sapiens (human)0.2329
Mitogen-activated protein kinase 10Homo sapiens (human)0.6933
Mitogen-activated protein kinase 1Rattus norvegicus (Norway rat)0.048
Myotonin-protein kinaseHomo sapiens (human)1
Mitogen-activated protein kinase 11Homo sapiens (human)0.2646
Mitogen-activated protein kinase 14Homo sapiens (human)0.39
P2X purinoceptor 7Homo sapiens (human)5
Serine/threonine-protein kinase 36Homo sapiens (human)1
Serine/threonine-protein kinase NLKHomo sapiens (human)1
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)1

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's7 (58.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajjar, JJ; Molski, TF; Nagarkatti, D; Sha'afi, RI; Syrbu, SI; Waterman, WH1
Gon, Y; Hashimoto, S; Hayashi, S; Horie, T; Kujime, K; Maruoka, S; Matsumoto, K; Takeshita, I1
Dun, Y; Sun, HY; Zhao, RR; Zhao, ZQ; Zhi, JM1
Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH1
Biffl, WL; Carnaggio, R; Ciesla, DJ; Johnson, JL; Moore, EE; Silliman, CC1
Bissonnette, SA; Brown, GE; Elia, AE; Stewart, MQ; Wilker, E; Yaffe, MB1
Baker, PR; O'Flaherty, JT; Owen, JS; Samuel, MP; Thomas, MJ; Wooten, RE; Wykle, RL1
Aomatsu, K; Arakawa, T; Fujita, H; Hato, F; Kamata, N; Kato, T; Kitagawa, S; Oshitani, N; Tamura, T1
Behar, J; Biancani, P; Cao, W; Harnett, KM; Ma, J1
Abdel-Al, M; Ditmyer, M; Howard, KM; Patel, N1
Cong, Q; Jiang, W; Li, MJ; Wang, YS; Xu, CJ; Ye, B1
Andrews, MA; Austin, M; Ibe, BO; Lazaro, M; Lustina, J; Raj, JU; Renteria, LS1

Other Studies

12 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and sb 203580

ArticleYear
Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Acyltransferases; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine

1999
p38 MAP kinase regulates TNF alpha-, IL-1 alpha- and PAF-induced RANTES and GM-CSF production by human bronchial epithelial cells.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:1

    Topics: Animals; Bronchi; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Chemokine CCL5; Enzyme Inhibitors; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Pyridines; Rabbits; Tumor Necrosis Factor-alpha

2000
Activated polymorphonuclear leukocytes induce cardiomyocyte apoptosis and the protective effects of carvedilol.
    Methods and findings in experimental and clinical pharmacology, 2002, Volume: 24, Issue:7

    Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Carbazoles; Carvedilol; Cells, Cultured; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Imidazoles; In Situ Nick-End Labeling; Microscopy, Electron; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Neutrophils; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Propanolamines; Pyridines; Rats; Signal Transduction

2002
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:6

    Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2002
Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
    Surgery, 2003, Volume: 134, Issue:1

    Topics: Apoptosis; Blood Preservation; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lysophosphatidylcholines; Mitogen-Activated Protein Kinases; Multiple Organ Failure; Neutrophils; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Pyridines; Saline Solution, Hypertonic

2003
Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Ligands; Luminescent Measurements; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Pyridines; Reactive Oxygen Species; Swine; Tumor Necrosis Factor-alpha; Zymosan

2004
Stress-induced platelet-activating factor synthesis in human neutrophils.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Acetyltransferases; Chromatography, Liquid; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Imidazoles; Mass Spectrometry; Neutrophils; Osmotic Pressure; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines

2005
Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases.
    Immunology, 2008, Volume: 123, Issue:2

    Topics: Butadienes; Chemotaxis, Leukocyte; Dose-Response Relationship, Immunologic; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Lipopolysaccharides; Lipoproteins; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines; Toll-Like Receptors

2008
Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:2

    Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Esophagus; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Signal Transduction; TRPV Cation Channels

2010
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:8

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Azepines; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles

2011
[Effects and mechanisms of platelet-activating factor on the invasiveness of ovarian cancer cells in vitro].
    Zhonghua fu chan ke za zhi, 2011, Volume: 46, Issue:12

    Topics: Blood Platelets; Blotting, Western; Carcinoma, Ovarian Epithelial; Cell Migration Assays; Cyclic AMP Response Element-Binding Protein; Female; Humans; Imidazoles; In Vitro Techniques; Matrix Metalloproteinase 2; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; Time Factors

2011
RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation.
    Cell proliferation, 2013, Volume: 46, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Flavonoids; Imidazoles; Lung; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Mutation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Sheep

2013