1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with r 59022 in 22 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (r 59022) | Trials (r 59022) | Recent Studies (post-2010) (r 59022) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 149 | 0 | 20 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | r 59022 (IC50) |
|---|---|---|---|
| Diacylglycerol kinase alpha | Homo sapiens (human) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 17 (77.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foreman, JC; Hayes, NA; McLeod, J | 1 |
| Boarder, MR; Jones, JA; Owen, PJ | 1 |
| de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD | 1 |
| Hirst, JJ; Jenkin, G; Rice, GE; Thorburn, GD | 1 |
| Dickinson, KE; Hirschowitz, BI; Hokin, LE; Pruitt, RE; Sekar, MC | 1 |
| Goldstein, L; Musch, MW | 1 |
| Holzer, P; Lippe, IT | 1 |
| Dufy, B; Mollard, P; Schlegel, W; Vacher, P; Winiger, BP | 1 |
| Chiang, CF; Hauser, G | 1 |
| Dale, MM; Penfield, A | 1 |
| Becker, EL; Gomez-Cambronero, J; Molski, TF; Sha'afi, RI | 1 |
| Alkon, DL; Inoue, H; Kouchi, T; Sakakibara, M; Yoshioka, T | 1 |
| Inagami, T; Inui, H; Kitami, Y; Kondo, T; Konishi, F | 1 |
| Au, BT; Hellewell, PG; Rossi, AG; Teixeira, MM; Williams, TJ | 1 |
| Bertagnolo, V; Borgatti, P; Capitani, S; Mazzoni, M; Osti, F; Previati, M | 1 |
| Momose, K; Nobe, K; Ohata, H | 1 |
| Boonen, GJ; de Koster, BM; Elferink, JG | 1 |
| Gay, JC | 1 |
| Kester, M | 1 |
| Jacobs, M; Pires, JG; Ramage, AG | 1 |
| Burt, RP; Chapple, CR; Marshall, I | 1 |
| Packham, MA; Rand, ML; Ruben, DH | 1 |
22 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and r 59022
| Article | Year |
|---|---|
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells.
Topics: Animals; Ascitic Fluid; Calcium; Cyclohexanones; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Inbred Strains; Substance P; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Phosphatidic acid accumulation and catecholamine release in adrenal chromaffin cells: stimulation by high potassium and by nicotine, and effect of a diacylglycerol kinase inhibitor R 59 022.
Topics: Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dose-Response Relationship, Drug; Nicotine; Phosphatidic Acids; Platelet Activating Factor; Potassium; Pyrimidinones; Thiazoles | 1991 |
Alkaline buffers release EDRF from bovine cultured aortic endothelial cells.
Topics: Animals; Arginine; Buffers; Cattle; Cells, Cultured; Cyclohexanones; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; Lipoprotein Lipase; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Pyrimidinones; Thiazoles | 1991 |
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1990 |
Muscarinic receptor antagonist activity of diacylglycerol lipase and kinase inhibitors.
Topics: Animals; Brain; Cells, Cultured; Cyclic GMP; Cyclohexanes; Cyclohexanones; Guinea Pigs; Heart; Lipoprotein Lipase; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Platelet Activating Factor; Pyrimidinones; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiazoles; Tritium | 1990 |
Hypotonicity stimulates phosphatidylcholine hydrolysis and generates diacylglycerol in erythrocytes.
Topics: Animals; Diglycerides; Erythrocytes; Glycerides; Hydrolysis; Hypotonic Solutions; In Vitro Techniques; Kinetics; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Pyrimidinones; Skates, Fish; Thiazoles | 1990 |
The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Diacylglycerol Kinase; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Substance P; Thiazoles | 1989 |
Inhibitors of 1,2-diacylglycerol kinase potentiate the TRH-induced stimulation of Ca2+-activated K+ current.
Topics: Calcium; Calcium Channels; Clone Cells; Diacylglycerol Kinase; Phosphotransferases; Platelet Activating Factor; Potassium Channels; Pyrimidinones; Thiazoles; Thyrotropin-Releasing Hormone; Vanadates | 1989 |
Effects of bradykinin, GTP gamma S, R59022 and N-ethylmaleimide on inositol phosphate production in NG108-15 cells.
Topics: Animals; Bradykinin; Cell Line; Drug Interactions; Ethylmaleimide; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hybrid Cells; Inositol; Inositol Phosphates; Kinetics; Mice; Neuroblastoma; Platelet Activating Factor; Pyrimidinones; Rats; Thiazoles; Thionucleotides | 1989 |
Comparison of the effects of indomethacin, RHC80267 and R59022 on superoxide production by 1,oleoyl-2,acetyl glycerol and A23187 in human neutrophils.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Cyclohexanes; Cyclohexanones; Diglycerides; Glycerides; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Platelet Activating Factor; Pyrimidinones; Superoxides; Thiazoles | 1987 |
The diacylglycerol kinase inhibitor R59022 potentiates superoxide production but not secretion induced by fMet-Leu-Phe: effects of leupeptin and the protein kinase C inhibitor H-7.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cytochalasin B; Diacylglycerol Kinase; Isoquinolines; Kinetics; Leupeptins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphotransferases; Piperazines; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rabbits; Superoxides; Thiazoles | 1987 |
Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium Chloride; Models, Biological; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Photoreceptor Cells, Invertebrate; Platelet Activating Factor; Pyrimidinones; Snails; Spermine; Thiazoles; Thionucleotides; Type C Phospholipases | 1994 |
Participation of diacylglycerol kinase in mitogenic signal transduction induced by platelet-derived growth factor in vascular smooth muscle cells.
Topics: Alkaloids; Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acid; Becaplermin; Cell Division; Cells, Cultured; Diacylglycerol Kinase; DNA; Enzyme Activation; Genistein; Humans; Isoflavones; Mitogens; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyrimidinones; Rats; Recombinant Proteins; Signal Transduction; Staurosporine; Thiazoles | 1994 |
Characterization of eosinophil homotypic aggregation.
Topics: Animals; Calcium; CD18 Antigens; Cell Aggregation; Drug Synergism; Eosinophils; Guinea Pigs; Leukotriene B4; Magnesium; Microscopy; Platelet Activating Factor; Pyrimidinones; Stimulation, Chemical; Superoxides; Thiazoles | 1995 |
Diacylglycerol kinase activity in rat liver nuclei.
Topics: Animals; Cell Nucleus; Detergents; Diacylglycerol Kinase; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Liver; Male; Microsomes, Liver; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Pyrimidinones; Rats; Rats, Sprague-Dawley; Substrate Specificity; Thiazoles | 1994 |
Effect of diacylglycerol kinase inhibitor, R59022 on cytosolic free calcium level and force development in guinea pig taenia coli.
Topics: Animals; Calcium; Colon; Guinea Pigs; Muscle Contraction; Platelet Activating Factor; Pyrimidinones; Thiazoles | 1993 |
Activation of neutrophil migration by dioctanoyl-sn-glycerol and fMet-Leu-Phe is controlled by different pathways.
Topics: Animals; Chemotaxis, Leukocyte; Diglycerides; Glyceryl Ethers; Guanosine 5'-O-(3-Thiotriphosphate); Macrophage Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rabbits; Thiazoles | 1993 |
Mechanism and regulation of neutrophil priming by platelet-activating factor.
Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Platelet-activating factor stimulates phosphatidic acid formation in cultured rat mesangial cells: roles of phospholipase D, diglyceride kinase, and de novo phospholipid synthesis.
Topics: Animals; Cells, Cultured; Choline; Diacylglycerol Kinase; Ethanolamines; Glomerular Mesangium; Glycerol; Hydrolysis; Male; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Phosphorus Radioisotopes; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors; Tritium | 1993 |
ICI 169,369, A 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Kinetics; Muscle Relaxation; Nitric Oxide; Platelet Activating Factor; Pyrimidinones; Quinolines; Rabbits; Serotonin Antagonists; Thiazoles; Vasodilator Agents | 1993 |
The role of diacylglycerol and activation of protein kinase C in alpha 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens.
Topics: Animals; Calcium; Carcinogens; Cyclohexanones; Diglycerides; Lipoprotein Lipase; Male; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine; Thiazoles; Vas Deferens | 1996 |
Exogenous diacylglycerols synergize with PAF with human platelets, but inhibit PAF-induced responses of rabbit platelets.
Topics: Animals; Blood Platelets; Cell Membrane Permeability; Diacylglycerol Kinase; Diglycerides; Drug Synergism; Enzyme Inhibitors; Humans; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrimidinones; Rabbits; Thiazoles | 1996 |