Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pulmicort

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with pulmicort in 5 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(pulmicort)
Trials
(pulmicort)
Recent Studies (post-2010) (pulmicort)
9,1561875524,9951,6381,785

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)pulmicort (IC50)
Glucocorticoid receptorHomo sapiens (human)0.0026
Progesterone receptorHomo sapiens (human)0.028
Glucocorticoid receptorRattus norvegicus (Norway rat)0.0029
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0045
Mineralocorticoid receptor Homo sapiens (human)0.014
Matrix metalloproteinase-9Homo sapiens (human)1.989
Androgen receptorRattus norvegicus (Norway rat)1.1725
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.0045
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0045
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0045

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Tuomisto, L; Vapaatalo, H1
Andersson, P; Brange, C; Chignard, M; Le Còuedic, JP1
Bickel, CA; Bochner, BS; Kaiser, J; Schleimer, RP1
Bazan, NG; Lukiw, WJ; Martinez, J; Pelaez, RP1
Boedker, M; Boetkjaer, A; Cui, JG; Lukiw, WJ; Zhao, Y1

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pulmicort

ArticleYear
Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:6

    Topics: Administration, Inhalation; Adult; Blood Platelets; Bronchodilator Agents; Budesonide; Catecholamines; Drug Synergism; Female; Histamine; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Platelet Count; Pregnenediones; Reference Values; Thromboxane B2

1992

Other Studies

4 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pulmicort

ArticleYear
Use of steroidal antiinflammatory drug provides further evidence for a potential role of PAF-acether in bronchial anaphylaxis.
    International archives of allergy and applied immunology, 1986, Volume: 81, Issue:2

    Topics: Anaphylaxis; Animals; Bronchi; Budesonide; Guinea Pigs; Immunoglobulin E; In Vitro Techniques; Platelet Activating Factor; Pregnenediones

1986
The effects of the potent glucocorticoid budesonide on adhesion of eosinophils to human vascular endothelial cells and on endothelial expression of adhesion molecules.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Budesonide; Cell Adhesion; Cell Adhesion Molecules; E-Selectin; Endothelium, Vascular; Eosinophils; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pregnenediones; Vascular Cell Adhesion Molecule-1

1993
Budesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1beta-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-31, Volume: 95, Issue:7

    Topics: Anti-Inflammatory Agents; Budesonide; Cells, Cultured; Cyclooxygenase 2; Dexamethasone; DNA-Binding Proteins; Drug Antagonism; Humans; Interleukin-1; Isoenzymes; Keratinocytes; Membrane Proteins; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Protein Binding; Transcription Factors; Transcriptional Activation

1998
Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells.
    Neuroscience letters, 2007, Oct-09, Volume: 426, Issue:1

    Topics: Anti-Inflammatory Agents; Budesonide; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Cyclooxygenase 2; Dihydropyridines; Dinoprostone; Drug Synergism; Encephalitis; Gene Expression; Humans; Neurons; Oxidative Stress; Platelet Activating Factor; Signal Transduction; Stress, Physiological; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation

2007