Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and phentolamine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with phentolamine in 6 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(phentolamine)
Trials
(phentolamine)
Recent Studies (post-2010) (phentolamine)
9,1561875529,141270265

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)phentolamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.396
Alpha-2A adrenergic receptorHomo sapiens (human)0.006
Cytochrome P450 2D6Homo sapiens (human)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0316
Alpha-2B adrenergic receptorHomo sapiens (human)0.018
Alpha-2C adrenergic receptorHomo sapiens (human)0.11
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0492
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0492
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0492
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0316
Alpha-1D adrenergic receptorHomo sapiens (human)0.0173
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.359
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.396
Alpha-1A adrenergic receptorHomo sapiens (human)0.0011
Alpha-1B adrenergic receptorHomo sapiens (human)0.0108
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.807
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0316
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.5495

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldenkov, GN; Grigorian, GIu; Mazaev, AV; Negresku, EV; Tkachuk, VA1
Avdonin, PV; Kulikov, VI; Svitina-Ulitina, IV1
Cervoni, P; Goldstein, BM; Herzlinger, H; Lai, FM; Quirk, GJ1
Goldenberg, MM; Meurer, RD1
Ashley, CJ; Sheppard, H; Tsien, WH1
Egresits, J; Kordás, K; László, F; László, FA; Morschl, E; Nemcsik, J; Pávó, I1

Other Studies

6 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and phentolamine

ArticleYear
[Biochemical features of platelet alpha2-adrenergic receptors and their connection with an increase in concentration of intracellular Ca2+].
    Biokhimiia (Moscow, Russia), 1989, Volume: 54, Issue:6

    Topics: Blood Platelets; Calcium; Cyclic AMP; Depression, Chemical; Epinephrine; Humans; Norepinephrine; Phentolamine; Platelet Activating Factor; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Serotonin; Stimulation, Chemical; Vasopressins; Yohimbine

1989
Stimulation of high-affinity hormone-sensitive GTPase of human platelets by 1-O-alkyl-2-O-acetyl-sn-glyceryl-3-phosphocholine (platelet activating factor).
    Biochemical and biophysical research communications, 1985, Aug-30, Volume: 131, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Blood Platelets; Cell Membrane; Epinephrine; GTP Phosphohydrolases; Guanosine Triphosphate; Humans; Phentolamine; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Receptors, Adrenergic, alpha

1985
Evidence for the lack of interaction between (+/-)-1-O-octadecyl-2-acetylglyceryl-3-phosphorylcholine and alpha-adrenoceptors in vivo and in vitro.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Angiotensin II; Animals; Blood Pressure; Cats; Epinephrine; In Vitro Techniques; Male; Nictitating Membrane; Norepinephrine; Phentolamine; Platelet Activating Factor; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Splanchnic Circulation

1984
A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat.
    Prostaglandins, 1984, Volume: 28, Issue:2

    Topics: Animals; Carrageenan; Dexamethasone; Dose-Response Relationship, Drug; Edema; Hindlimb; Indomethacin; Male; Muscles; Phentolamine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline; Verapamil; Yohimbine

1984
Variable responses of human platelets to synthetic platelet activating factor and their modification by epinephrine.
    Thrombosis research, 1982, Nov-15, Volume: 28, Issue:4

    Topics: Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Indomethacin; Male; Phentolamine; Platelet Activating Factor; Platelet Aggregation

1982
Synergistic interaction of endogenous platelet-activating factor and vasopressin in generating angina in rats.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Angina Pectoris; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Epinephrine; Ginkgolides; Heart Rate; Hormone Antagonists; Injections, Intravenous; Lactones; Male; Myocardial Ischemia; Ornipressin; Phentolamine; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Vasopressin; Time Factors; Vasoconstrictor Agents; Vasopressins

2004