1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with pf 5901 in 9 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (pf 5901) | Trials (pf 5901) | Recent Studies (post-2010) (pf 5901) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 84 | 0 | 14 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | pf 5901 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.65 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.776 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 5.3 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 5.3 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hellewell, PG; Jose, PJ; Williams, TJ | 1 |
| Donigi-Gale, D; Hogaboam, CM; Shoupe, TS; Wallace, JL | 1 |
| Donigi-Gale, D; Herd, CM; Page, CP; Shoupe, TS | 1 |
| Befus, AD; Bissonnette, EY; Donigi-Gale, D; Hogaboam, CM; Shoupe, TS; Wallace, JL | 1 |
| Anderson, G; Fennessy, M | 1 |
| Jones, CJ; MacIntyre, DE; McMillan, RM; Rossi, AG | 1 |
| Donigi-Gale, D; Kilfeather, S; Okiji, S; Page, CP; Schoupe, TS; Seeds, EA | 1 |
| Beadle, RE; Holmes, EP; Seahorn, TL; Venugopalan, CS | 1 |
| Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N | 1 |
9 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pf 5901
| Article | Year |
|---|---|
Inflammatory mechanisms in the passive cutaneous anaphylactic reaction in the rabbit: evidence that novel mediators are involved.
Topics: Animals; Aprotinin; Blood Coagulation Factors; Bradykinin; Complement C5a; Dinoprostone; Edema; Fluoroacetates; Histamine Antagonists; Immunoglobulin E; Indomethacin; Lipoxygenase Inhibitors; Male; Neutrophils; Oligopeptides; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Quinolines; Rabbits; Specific Pathogen-Free Organisms | 1992 |
PF-5901 inhibits gastrointestinal platelet-activating factor synthesis in vivo.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Intestinal Mucosa; Jejunum; Male; Nematode Infections; Nippostrongylus; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic | 1992 |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on PAF-induced airway responses in neonatally immunized rabbits.
Topics: Administration, Inhalation; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Female; Histamine; Immunization; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinolines; Rabbits; SRS-A | 1992 |
Platelet-activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline-based compounds.
Topics: Animals; Biological Assay; Calcimycin; Histamine; Lipoxygenase Inhibitors; Male; Mast Cells; Molecular Structure; Naphthaleneacetic Acids; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Quinolines; Rats; Rats, Inbred Strains | 1992 |
Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig.
Topics: Animals; Female; Guinea Pigs; Histamine; Hydroxyquinolines; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Lung Compliance; Male; Platelet Activating Factor; Quinolines; SRS-A | 1988 |
Stimulation of human polymorphonuclear leukocytes by leukotriene B4 and platelet-activating factor: an ultrastructural and pharmacological study.
Topics: Acetylglucosaminidase; Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Ionomycin; Leukotriene B4; Lipoxygenase Inhibitors; Microscopy, Electron; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Quinolines | 1993 |
Role of lipoxygenase metabolites in platelet-activating factor- and antigen-induced bronchial hyperresponsiveness and eosinophil infiltration.
Topics: Animals; Benzofurans; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; Humans; Leukotriene Antagonists; Lipoxygenase; Lipoxygenase Inhibitors; Male; Ovalbumin; Platelet Activating Factor; Pulmonary Eosinophilia; Quinolines | 1995 |
Responses of guinea-pig lung parenchymal strips to tracheobronchial lavage fluid from horses affected with summer pasture-associated obstructive pulmonary disease.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Dinoprostone; Guinea Pigs; Histamine; Horse Diseases; Horses; In Vitro Techniques; Leukotriene D4; Lung; Lung Diseases, Obstructive; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Poaceae; Prostaglandin Antagonists; Quinolines; Reference Values; Seasons; Trachea; Xanthenes; Xanthones | 1998 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan | 2002 |