Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pd 98059

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with pd 98059 in 15 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(pd 98059)
Trials
(pd 98059)
Recent Studies (post-2010) (pd 98059)
9,1561875524,93931,001

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)pd 98059 (IC50)
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)2.8
Luciferin 4-monooxygenasePhotinus pyralis (common eastern firefly)6.3
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)2.8
Prostaglandin G/H synthase 1Homo sapiens (human)1
Mitogen-activated protein kinase 1Homo sapiens (human)2.8
Dual specificity mitogen-activated protein kinase kinase 2 Rattus norvegicus (Norway rat)4.2
Dual specificity mitogen-activated protein kinase kinase 1 Rattus norvegicus (Norway rat)4.2
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)2.4

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (26.67)18.2507
2000's9 (60.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coffer, PJ; Geijsen, N; Koenderman, L; Lammers, JW; M'rabet, L; Maikoe, T; Raaijmakers, JA; Schweizer, RC1
Minami, K; Mue, S; Ohuchi, K; Xiao, YQ1
Hajjar, JJ; Molski, TF; Nagarkatti, D; Sha'afi, RI; Syrbu, SI; Waterman, WH1
Fukunaga, K; Miyamoto, E; Miyazaki, K; Munir, I; Okamura, H1
Chang, PY; Chen, CH; Henry, PD; Jiang, T; Lee, YT; Lu, SC; Luo, S1
Hanif, S; Khan, FL; Rahman, HB; Rahman, IH; Rasheed, H; Saeed, SA; Shah, BH; Shariff, AH1
Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH1
Chan, JS; Filep, JG; József, L; Khreiss, T1
Slomiany, A; Slomiany, BL2
Bazan, HE; Taheri, F1
Beer, DG; Behar, J; Cao, W; Chin, YE; Lambeth, D; Si, J; Wands, J1
Abdallah, MF; Ibe, BO; Portugal, AM; Raj, JU1
Ajiro, Y; Giles, WR; Saegusa, N; Spitzer, KW; Stafforini, DM1
Andrews, MA; Austin, M; Ibe, BO; Lazaro, M; Lustina, J; Raj, JU; Renteria, LS1

Other Studies

15 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and pd 98059

ArticleYear
Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function.
    The Biochemical journal, 1998, Jan-01, Volume: 329 ( Pt 1)

    Topics: Androstadienes; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Cytokines; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Kinases; Respiratory Burst; Signal Transduction; Wortmannin; Zymosan

1998
Pharmacological analysis of protein kinases responsible for chemotaxis of rat peritoneal neutrophils.
    European journal of pharmacology, 1998, Nov-06, Volume: 360, Issue:2-3

    Topics: Animals; Ascitic Fluid; Benzoquinones; Chemokine CXCL2; Chemokines, CXC; Chemotactic Factors; Chemotaxis; Enzyme Inhibitors; Flavonoids; Growth Substances; Intercellular Signaling Peptides and Proteins; Lactams, Macrocyclic; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Monokines; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin

1998
Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Acyltransferases; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine

1999
Mitogen-activated protein kinase activation and regulation of cyclooxygenase 2 expression by platelet-activating factor and hCG in human endometrial adenocarcinoma cell line HEC-1B.
    Journal of reproduction and fertility, 1999, Volume: 117, Issue:1

    Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents, Hormonal; Chorionic Gonadotropin; Cyclic AMP; Cyclooxygenase 2; Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Flavonoids; Humans; Isoenzymes; Isoquinolines; Medroxyprogesterone Acetate; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Cells, Cultured; Wortmannin

1999
Oxidized low-density lipoprotein downregulates endothelial basic fibroblast growth factor through a pertussis toxin-sensitive G-protein pathway: mediator role of platelet-activating factor-like phospholipids.
    Circulation, 2001, Jul-31, Volume: 104, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; GTP-Binding Proteins; Indoles; Isoquinolines; Lipoproteins, LDL; Pertussis Toxin; Phospholipases A; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Triazoles; Virulence Factors, Bordetella

2001
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
    Experimental & molecular medicine, 2001, Dec-31, Volume: 33, Issue:4

    Topics: Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Flavonoids; Humans; In Vitro Techniques; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Pyrrolidinones; Serotonin; Thromboxane A2; Verapamil

2001
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:6

    Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2002
Activation of extracellular signal-regulated kinase couples platelet-activating factor-induced adhesion and delayed apoptosis of human neutrophils.
    Cellular signalling, 2004, Volume: 16, Issue:7

    Topics: Androstadienes; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Caspase 3; Caspases; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Granulocytes; Humans; Inflammation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activating Factor; Signal Transduction; Time Factors; Up-Regulation; Wortmannin

2004
Cytosolic phospholipase A2 activation in Helicobacter pylori lipopolysaccharide-induced interference with gastric mucin synthesis.
    IUBMB life, 2006, Volume: 58, Issue:4

    Topics: Androstadienes; Animals; Arachidonic Acids; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucosa; Ginkgolides; Lactones; Lipopolysaccharides; Models, Biological; Mucins; Organophosphonates; Phosphatidylcholines; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Wortmannin

2006
Interference by leptin with Helicobacter pylori lipopolysaccharide-induced cytosolic phospholipase A2 activation in gastric mucosal cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:1

    Topics: Androstadienes; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gastric Mucins; Gastric Mucosa; Ginkgolides; Lactones; Leptin; Lipopolysaccharides; Organophosphonates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin

2007
Platelet-activating factor overturns the transcriptional repressor disposition of Sp1 in the expression of MMP-9 in human corneal epithelial cells.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:5

    Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappaB-Inducing Kinase; Phosphorylation; Plasmids; Platelet Activating Factor; Protein Serine-Threonine Kinases; Repressor Proteins; Sp1 Transcription Factor; Transcription Factor AP-1; Transfection

2007
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:1

    Topics: Adenocarcinoma; Arachidonic Acids; Barrett Esophagus; Cell Line, Tumor; Enzyme Inhibitors; Esophageal Neoplasms; Flavonoids; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; MAP Kinase Kinase 1; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 5; NADPH Oxidases; Phospholipases A2, Cytosolic; Phospholipid Ethers; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Transfection; Up-Regulation

2008
Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases.
    Cell proliferation, 2008, Volume: 41, Issue:2

    Topics: Animals; Azepines; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Female; Flavonoids; Hypoxia; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; Oxygen; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Sheep; Structure-Activity Relationship; Triazoles

2008
Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:6

    Topics: Acidosis; Alkalosis; Animals; Azepines; Benzophenanthridines; Dose-Response Relationship, Drug; Flavonoids; Guanidines; Guinea Pigs; Heart Ventricles; Hydrogen-Ion Concentration; Indoles; Ion Transport; Maleimides; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Kinase Inhibitors; Receptors, G-Protein-Coupled; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Sulfones; Time Factors; Triazoles

2011
RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation.
    Cell proliferation, 2013, Volume: 46, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Flavonoids; Imidazoles; Lung; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Mutation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Sheep

2013