1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with ovalbumin in 106 studies
Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (ovalbumin) | Trials (ovalbumin) | Recent Studies (post-2010) (ovalbumin) |
---|---|---|---|---|---|
9,156 | 187 | 552 | 19,565 | 63 | 5,664 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (17.92) | 18.7374 |
1990's | 69 (65.09) | 18.2507 |
2000's | 15 (14.15) | 29.6817 |
2010's | 2 (1.89) | 24.3611 |
2020's | 1 (0.94) | 2.80 |
Authors | Studies |
---|---|
Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB | 2 |
Zhang, JN | 1 |
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB | 1 |
Cordeiro, RS; Diaz, BL; e Silva, PM; Lima, MC; Martins, MA; Pasquale, CP; Rihoux, JP; Vargaftig, BB | 1 |
Iwamoto, I; Matsumura, R; Nakajima, H; Takatsu, K; Tomioka, H; Tomoe, S; Yoshida, S | 1 |
Fisher, RA; Hines, KL | 1 |
Iwahisa, Y; Okamoto, H; Terasawa, M | 1 |
Lefort, J; Perrisoud, D; Pretolani, M; Vargaftig, BB; Venco, C | 1 |
Bernat, A; Herbert, JM; Laplace, MC; Maffrand, JP; Salel, V | 1 |
Alves, AC; Cordeiro, RS; Diaz, BL; e Silva, PM; Lima, MC; Martins, MA | 1 |
Bittinger, M; Dorsch, W; Kaas, A; Kreher, B; Müller, A; Wagner, H | 1 |
Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 2 |
Lewis, SA; Raeburn, D; Underwood, SL | 1 |
Imanishi, N; Morooka, S; Uchida, M | 1 |
Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB | 1 |
Cordeiro, RS; Lima, MC; Martins, MA; Perez, SA; Silva, PM; Vargaftig, BB | 1 |
Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M | 1 |
Berti, F; Braquet, P; Rossoni, G | 1 |
Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
Herbert, JM; Lespy, L; Maffrand, JP | 1 |
Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
Imanishi, N; Morooka, S; Sugasawa, T | 1 |
Heuer, HO | 2 |
Ferreira, AP; Jancar, S; Macedo, MS; Riffo-Vasquez, Y | 1 |
Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Yamaguchi, T | 1 |
Chan, CC; Chee, P; Ford-Hutchinson, A; McKee, K; Tagari, P | 1 |
Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
Braquet, P; Friedrich, G; Giessler, J; Hirschelmann, R; Madi, S | 1 |
Arima, M; Makino, S; Sagara, H; Terashi, Y; Yukawa, T | 1 |
Bachelet, M; Bereziat, G; Dumarey, C; Fouque, F; Havet, N; Lagente, V; Masliah, J; Vargaftig, BB | 1 |
Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
Bachelet, M; Dumarey, C; Lefort, J; Malanchere, E; Pretolani, M; Silva, P; Vargaftig, BB | 1 |
Howell, RE | 1 |
Akutsu, I; Amagai, M; Fukuda, T; Makino, S; Motojima, S; Numao, T | 1 |
Conklyn, M; Showell, HJ; Watson, JW | 1 |
Beattie, LL; Ishida, K; Schellenberg, RR; Thomson, RJ; Wiggs, B | 1 |
Braquet, P; Cirino, M; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B | 1 |
Braquet, P; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B | 1 |
Briand, H; Burka, JF; Pasutto, FM; Scott-Savage, P | 1 |
Casals-Stenzel, J; Heuer, H | 1 |
Calixto, JB; Medeiros, YS; Torres, RC | 1 |
Aharony, D; Redkar-Brown, DG | 1 |
Fitzgerald, MF; Moncada, S; Parente, L | 1 |
Darius, H; Lefer, AM; Lefer, DJ; Smith, JB | 1 |
Borgeat, P; Braquet, P; Harczy, M; Maclouf, J; Pradelles, P; Sirois, P | 1 |
Lefort, J; Pretolani, M; Vargaftig, BB | 1 |
Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
Braquet, P; Coyle, AJ; Page, CP; Touvay, C; Urwin, SC; Villain, B | 1 |
Aursudkij, B; Barnes, PJ; Chung, KF; Dent, G; Evans, TW; Rogers, DF | 1 |
Cirino, M; Desquand, S; Hadvary, P; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Vargaftig, BB | 1 |
Casals-Stenzel, J | 1 |
Henderson, B; Higgs, GA; Pettipher, ER | 1 |
Cirino, M; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
Morley, J; Page, CP; Paul, W | 1 |
Alonso, F; Barat, A; Egido, J; Sánchez-Crespo, M | 1 |
Abelli, L; Evangelista, S; Manzini, S; Page, CP; Perretti, F; Seeds, EA | 1 |
Giessler, C; Heinroth-Hoffmann, I; Meissner, N; Mest, HJ; Pönicke, K | 1 |
Bindi, D; Franchi-Micheli, S; Gentilini, G; Mugnai, S; Zilletti, L | 1 |
Arima, M; Makino, S; Yukawa, T | 1 |
Asakura, K; Narita, S | 2 |
Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
Parnell, DW; Spellman, JM; Stephens, DJ; Yanni, JM | 1 |
Choi, IH; Ha, TY; Lee, DG; Lee, HK; Lee, JH; Park, JS; Park, YM | 1 |
Coëffier, E; Joseph, D; Vargaftig, BB | 2 |
Howell, RE; Kovalsky, MP; Laemont, KD | 1 |
Dahlén, SE; Jonsson, EW | 1 |
Campos, MG; Church, MK; Joseph, D; Lefort, J; Pretolani, M; Ruffié, C; Vargaftig, BB | 1 |
Hanss, J; Page, CP; Seeds, EA | 1 |
Broadley, KJ; Thorne, JR | 1 |
Amorim, CZ; Cordeiro, RS; Vargaftig, BB | 2 |
Bozza, PT; Castro Faria Neto, HC; Cordeiro, RS; e Silva, PM; Lima, MC; Martins, MA; Vargaftig, BB | 1 |
Baker, J; Bertrand, C; Geppetti, P; Nadel, JA; Yamawaki, I | 1 |
Fu, J; Li, PS; Yu, HP | 1 |
Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
Cheng, JB; Cohan, VL; Pillar, JS; Shirley, JT; Showell, HJ; Watson, JW | 1 |
Han, SH; Tsai, CF; Tsai, JJ; Wang, SR | 1 |
Donigi-Gale, D; Kilfeather, S; Okiji, S; Page, CP; Schoupe, TS; Seeds, EA | 1 |
Ishizaki, M; Kawata, E; Mori, J | 1 |
Bernat, A; Herbert, JM; Tibiriça, E | 1 |
Bae, SJ; Hakugawa, J; Katayama, I; Tanaka, Y; Vinuesa, MA | 1 |
Boichot, E; Braquet, P; Carre, C; Guinot, P; Lagente, V; Mencia-Huerta, JM | 1 |
Akiyama, H; Goda, Y; Okunuki, H; Sakushima, J; Sawada, JI; Teshima, R; Toyoda, M | 1 |
Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
Apostoliti, F; Breschi, MC; Martinotti, E; Nieri, P | 1 |
Alessandrini, AL; Ishii, S; Klein, A; Pinho, V; Shimizu, T; Teixeira, MM | 1 |
Brandt, EB; Finkelman, FD; Hershko, D; Muntel, EE; Rothenberg, ME; Scribner, TA; Strait, RT; Wang, Q; Zimmermann, N | 1 |
Imoto, K; Kato, M; Miyaji, S; Miyake, H; Nakamura, M; Oda, T | 1 |
Amendoeira, FC; Bandeira-Melo, C; Bozza, PT; Castro-Faria-Neto, HC; Chedier, LM; Figueiredo, MR; Frutuoso, VS; Gomes, GS; Kaplan, MA; Vieira-de-Abreu, A; Weller, PF; Zanon, C | 1 |
Cui, S; Kurata, Y; Liu, W; Ruan, Z; Shibamoto, T | 1 |
Basilico, F; Bombardelli, E; De Palma, A; Mauri, P; Morazzoni, P; Pozzi, F; Riva, A; Rossoni, G | 1 |
Fukushima, A; Igarashi, A; Okumura, N; Sumi, T; Ueno, H; Yamagishi, T | 1 |
Ebihara, S; Kurachi, H; Watanabe, Y | 1 |
Cloutier, S; Richter, M; Sirois, P | 1 |
Karasuyama, H; Kawano, Y; Minegishi, Y; Mukai, K; Nishikado, H; Obata, K; Shimizu, T; Shindou, H; Tsujimura, Y; Yoshida, M | 1 |
Kato, Y; Kremenik, MJ; Matsumoto, T; Shiva, D; Yano, H | 1 |
Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H; Zhang, W | 1 |
Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T | 1 |
Kuda, Y; Kurata, Y; Shibamoto, T; Tanida, M; Wang, M | 1 |
Abas, F; Israf, DA; Khoo, LW; Kow, ASF; Lee, MT; Shaari, K; Tan, JW; Tham, CL | 1 |
1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ovalbumin
Article | Year |
---|---|
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
Topics: Adult; Animals; Biological Availability; Bronchoconstriction; Chromatography, Liquid; Diterpenes; Ginkgo biloba; Ginkgolides; Guinea Pigs; Histamine; Humans; Lactones; Male; Mass Spectrometry; Models, Molecular; Molecular Conformation; Ovalbumin; Plant Extracts; Platelet Activating Factor; Terpenes; Thromboxane B2 | 2006 |
105 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ovalbumin
Article | Year |
---|---|
Interference of BN 52021, an antagonist of PAF, with different forms of active anaphylaxis in the guinea-pig: importance of the booster injection.
Topics: Anaphylaxis; Animals; Bronchoconstriction; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; Immunization, Secondary; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1991 |
[Interference of platelet-activating factor antagonist, BN50739 with the releasing of inflammatory mediators from anaphylactic lung of guinea pig].
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Female; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; Prostaglandins F; SRS-A; Thromboxane B2; Triazoles | 1992 |
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles | 1992 |
Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized rats.
Topics: Animals; Antigens; Bradykinin; Cetirizine; Cytoplasmic Granules; Female; Histamine; Histamine H1 Antagonists; Leukocyte Count; Male; Mast Cells; Meclizine; Ovalbumin; Platelet Activating Factor; Pleurisy; Rats; Rats, Wistar; Serotonin | 1992 |
CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea.
Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; CD4-Positive T-Lymphocytes; Cromolyn Sodium; Eosinophils; Evaluation Studies as Topic; Hypersensitivity, Delayed; Injections, Intraperitoneal; Interleukin-5; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Pyridinium Compounds; T-Lymphocytes, Regulatory; Trachea | 1992 |
Regulation of hepatic glycogenolysis and vasoconstriction during antigen-induced anaphylaxis.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Eicosanoids; Epitopes; Female; Glycogen; Liver; Nitric Oxide; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles; Vasoconstriction | 1992 |
Suppression of the Arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor.
Topics: Animals; Arthus Reaction; Azepines; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Male; Molecular Structure; Ovalbumin; Pancreatitis; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Skin Diseases; Triazoles | 1992 |
Inhibition by azelastine of the effects of platelet-activating factor in lungs from actively sensitised guinea-pigs.
Topics: Animals; Arachidonic Acid; Bronchoconstriction; Guinea Pigs; Histamine; Immunization; Injections, Intra-Arterial; Leukotrienes; Lung; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Artery; Thromboxane B2 | 1992 |
Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigen.
Topics: Allergens; Animals; Antigens; Edema; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Skin Diseases; Thiazoles | 1992 |
Pharmacological modulation of the late eosinophilia induced by antigen in actively sensitized rats.
Topics: Animals; Antigens; Arachidonic Acid; Cyclooxygenase Inhibitors; Eosinophilia; Female; Leukocyte Count; Lipoxygenase Inhibitors; Male; Ovalbumin; Platelet Activating Factor; Pleurisy; Rats; Rats, Wistar | 1992 |
Antiasthmatic effects of Galphimia glauca, gallic acid, and related compounds prevent allergen- and platelet-activating factor-induced bronchial obstruction as well as bronchial hyperreactivity in guinea pigs.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Gallic Acid; Guinea Pigs; Male; Ovalbumin; Phytotherapy; Plant Extracts; Platelet Activating Factor; Quercetin | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
RP 59227, a novel PAF receptor antagonist: effects in guinea pig models of airway hyperreactivity.
Topics: Animals; Antigens; Azepines; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridines; Thiazoles; Triazoles | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines | 1992 |
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles | 1991 |
Effect of azelastine on platelet-activating factor and antigen-induced pleurisy in rats.
Topics: Animals; Antigens; Female; Histamine; Histamine H1 Antagonists; Leukocytes; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pleural Effusion; Pleurisy; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles | 1990 |
Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021.
Topics: Animals; Biological Assay; Diterpenes; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Kidney; Lactones; Male; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; SRS-A; Thromboxane B2 | 1990 |
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Vascular permeability increase in the mouse paw during the passive anaphylaxis reaction.
Topics: Animals; Capillary Permeability; Edema; Exudates and Transudates; Female; Histamine; Immunoglobulin E; Immunoglobulins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Serotonin | 1991 |
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Lung; Male; Mice; Mice, Inbred Strains; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Propranolol; Pyrilamine; Respiration; Triazoles | 1991 |
PAF antagonists do not modify IgE antibody production in mice.
Topics: Animals; Antibodies, Anti-Idiotypic; Female; Immunoglobulin E; Mice; Mice, Inbred BALB C; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Vascular Patency | 1991 |
Inhibition of neutral endopeptidase potentiates bronchial contraction induced by immune response in guinea pigs in vitro.
Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Serotonin; SRS-A; Thiorphan | 1991 |
Effect of NZ-107 on late-phase airway responses and airway hyperreactivity in guinea pigs.
Topics: Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Bronchoconstriction; Drug Hypersensitivity; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyridazines; Respiratory Hypersensitivity | 1991 |
Inhibition of active anaphylaxis in mice and guinea pigs by the new hetrazepinoic PAF antagonist bepafant (WEB 2170).
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Bronchoconstriction; Guinea Pigs; Immunization; Male; Mice; Ovalbumin; Platelet Activating Factor; Propranolol; Pulmonary Ventilation; Pyrilamine; Triazoles | 1991 |
Eosinophil-eicosanoid interactions: inhibition of eosinophil chemotaxis in vivo by a LTD4-receptor antagonist.
Topics: Animals; Chemotaxis, Leukocyte; Conjunctiva; Eicosanoids; Eosinophils; Guinea Pigs; Histamine; Histocytochemistry; Indium Radioisotopes; Male; Ovalbumin; Platelet Activating Factor; Propionates; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A | 1990 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Allergen-induced bronchospasm in passively sensitized guinea pigs: influence of new substances in comparison to reference compounds.
Topics: Acrylates; Allergens; Animals; Azepines; Benzoates; Bronchial Spasm; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Male; Ovalbumin; Phospholipases A; Platelet Activating Factor; Tetrazoles; Thienopyridines; Triazoles | 1991 |
[Involvement of platelet activating factor (PAF) in ovalbumin antigen-induced late asthmatic response and increase of airway hyperresponsiveness in a guinea pig experimental model of asthma].
Topics: Airway Resistance; Animals; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Male; Ovalbumin; Platelet Activating Factor; Triazoles | 1991 |
Antigen-dependent activation of alveolar macrophages from ovalbumin-sensitized guinea-pigs: relevance of the route of administration and the amount of antigen provided.
Topics: Aerosols; Animals; Antigens; Female; Guinea Pigs; Immunoglobulin G; In Vitro Techniques; Injections, Subcutaneous; Macrophage Activation; Male; Ovalbumin; Platelet Activating Factor; Pulmonary Alveoli | 1990 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
Protection by nedocromil sodium of active immunization-induced bronchopulmonary alterations in the guinea pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchoalveolar Lavage Fluid; Constriction, Pathologic; Eosinophils; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotrienes; Male; Nedocromil; Ovalbumin; Platelet Activating Factor; Quinolones; Respiratory Hypersensitivity; Thromboxane B2 | 1990 |
Multiple mechanisms of xanthine actions on airway reactivity.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Administration, Inhalation; Aerosols; Animals; Blood Pressure; Bronchi; Bronchoconstriction; Bronchodilator Agents; Carbachol; Guinea Pigs; Heart Rate; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Theophylline; Xanthines | 1990 |
[Antigen-induced biphasic eosinophil infiltration in the airways of actively sensitized guinea pigs and its inhibition by PAF antagonist and cyclosporin A].
Topics: Animals; Asthma; Bronchi; Cyclosporins; Eosinophilia; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridinium Compounds; Time | 1990 |
IgG1-mediated acute pulmonary hypersensitivity response in the guinea pig. Involvement of specific lipid mediators.
Topics: Acute Disease; Animals; Azepines; Bronchoconstriction; Dicarboxylic Acids; Dose-Response Relationship, Drug; Furans; Guinea Pigs; Immunization; Immunoglobulin G; Indoles; Lipids; Lung; Male; Ovalbumin; Phenylcarbamates; Piroxicam; Platelet Activating Factor; Propranolol; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Sulfonamides; Tosyl Compounds; Triazoles | 1990 |
Inhibition of antigen-induced airway hyperresponsiveness, but not acute hypoxia nor airway eosinophilia, by an antagonist of platelet-activating factor.
Topics: Acetylcholine; Airway Resistance; Animals; Bronchial Provocation Tests; Bronchial Spasm; Connective Tissue Cells; Eosinophils; Epithelial Cells; Guinea Pigs; Hypersensitivity; Isoquinolines; Ovalbumin; Platelet Activating Factor; Platelet Aggregation; Respiratory System | 1990 |
The booster injection of antigen during active sensitization of guinea-pig modifies the anti-anaphylactic activity of the PAF antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Azepines; Blood Cell Count; Bronchi; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Histamine; Immunization, Secondary; Immunoglobulin G; Lung; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; Spectrometry, Fluorescence; Thromboxane B2; Triazoles | 1990 |
Interference of the PAF-acether antagonist BN 52021 with passive anaphylaxis in the guinea-pig.
Topics: Airway Resistance; Anaphylaxis; Animals; Diterpenes; Female; Ginkgolides; Guinea Pigs; Histamine Release; In Vitro Techniques; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Thromboxane B2 | 1987 |
Interference of the PAF-acether antagonist BN 52021 with anaphylaxis in the guinea pig.
Topics: Anaphylaxis; Animals; Guinea Pigs; Histamine Release; In Vitro Techniques; Lung; Ovalbumin; Platelet Activating Factor | 1987 |
Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Platelet Activating Factor; Respiratory System; SRS-A; Trachea | 1989 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles | 1989 |
Tracheal responsiveness to histamine, PAF-acether and acetylcholine in normal and actively ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; Histamine; Immunization; Indomethacin; Isometric Contraction; Male; Ovalbumin; Platelet Activating Factor; Quinacrine; Trachea | 1989 |
Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198,615.
Topics: Animals; Antigens; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; Pyrilamine; SRS-A; Trachea | 1989 |
Anaphylactic release of platelet activating factor acether and eicosanoids from lungs of guinea pigs sensitized to ovalbumin aerosol.
Topics: Anaphylaxis; Animals; Fatty Acids, Unsaturated; Guinea Pigs; Leukotriene B4; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Thromboxane B2 | 1987 |
Role of platelet-activating factor-acether in mediating guinea pig anaphylaxis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprazolam; Anaphylaxis; Animals; Anti-Inflammatory Agents; Benzodiazepines; Blood Pressure; Diphenhydramine; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyrazoles | 1986 |
Inhibitory effects of a novel platelet activating factor (PAF) antagonist (BN 52021) on antigen-induced prostaglandin and thromboxane formation by the guinea pig lung.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Diterpenes; Female; Ginkgolides; Guinea Pigs; In Vitro Techniques; Kinetics; Lactones; Lung; Male; Ovalbumin; Plant Extracts; Platelet Activating Factor; Prostaglandins; Prostaglandins E; Thromboxane B2; Thromboxanes | 1986 |
Active immunization induces lung hyperresponsiveness in the guinea pig. Pharmacologic modulation and triggering role of the booster injection.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchial Spasm; Capillary Permeability; Female; Guinea Pigs; Histamine; Immunization; Immunization, Secondary; Kinetics; Lung; Male; Ovalbumin; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Respiratory Hypersensitivity; SRS-A; Thromboxane B2 | 1988 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
The effect of the selective PAF antagonist BN 52021 on PAF- and antigen-induced bronchial hyper-reactivity and eosinophil accumulation.
Topics: Animals; Antigens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Lactones; Male; Ovalbumin; Platelet Activating Factor | 1988 |
Effect of a Paf antagonist, WEB 2086, on airway microvascular leakage in the guinea-pig and platelet aggregation in man.
Topics: Adenosine Diphosphate; Animals; Azepines; Capillary Permeability; Guinea Pigs; Humans; In Vitro Techniques; Male; Ovalbumin; Platelet Activating Factor; Platelet Aggregation; Triazines; Triazoles | 1988 |
Interference of the Paf antagonist Ro 19-3704 with Paf and antigen-induced bronchoconstriction in the guinea-pig.
Topics: Aerosols; Animals; Blood Cell Count; Bronchodilator Agents; Female; Glyceryl Ethers; Guinea Pigs; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Alveoli; Thiazoles | 1988 |
Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis.
Topics: Administration, Oral; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Immunization; Immunization, Passive; Injections, Intravenous; Male; Mice; Ovalbumin; Platelet Activating Factor; Pyrilamine; Respiration; Triazines; Triazoles | 1987 |
PAF-acether in chronic arthritis.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Disease Models, Animal; Humans; Inflammation; Injections, Intra-Articular; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Synovial Fluid | 1987 |
A study with BN 52021 demonstrates the involvement of PAF-acether in IgE-dependent anaphylactic bronchoconstriction.
Topics: Aerosols; Anaphylaxis; Animals; Blood Platelets; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunoglobulin E; Lactones; Male; Neutrophils; Ovalbumin; Plant Extracts; Platelet Activating Factor; Propranolol | 1986 |
Platelets and bronchospasm.
Topics: Airway Resistance; Animals; Bronchial Spasm; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1984 |
Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Basement Membrane; Disease Models, Animal; Histamine; Kidney Glomerulus; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Sickness | 1982 |
Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airway inflammation in guinea pigs.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Capsaicin; Dextrans; Dyspnea; Fluorescein-5-isothiocyanate; Guinea Pigs; Histamine; Leukocytes; Male; Ovalbumin; Platelet Activating Factor | 1993 |
Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Catecholamines; Eicosanoids; Epinephrine; Guinea Pigs; Heart; Histamine Release; Kinetics; Leukotrienes; Male; Norepinephrine; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1995 |
GABA-mediated inhibition of the anaphylactic response in the guinea-pig trachea.
Topics: Anaphylaxis; Animals; beta-Alanine; Bronchial Hyperreactivity; Capsaicin; Drug Interactions; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine Release; Macrophage Activation; Macrophages, Alveolar; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Nipecotic Acids; Ovalbumin; Platelet Activating Factor; Proline; Receptors, GABA; Tetrodotoxin; Trachea | 1995 |
Effect of YM264 on the airway hyperresponsiveness and the late asthmatic response in a guinea pig model of asthma.
Topics: Aerosols; Airway Resistance; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; Immunization; Male; Ovalbumin; Piperazines; Platelet Activating Factor; Random Allocation; Statistics, Nonparametric; Thiazoles; Thiazolidines; Time Factors; Trachea | 1995 |
The role of platelet-activating factor on histamine hypersensitivity in nasal allergy in guinea pig models.
Topics: Allergens; Animals; Guinea Pigs; Histamine Release; Hypersensitivity; Male; Ovalbumin; Platelet Activating Factor; Thiazoles; Thiazolidines | 1993 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use.
Topics: Administration, Topical; Anaphylaxis; Animals; Benzimidazoles; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Ophthalmic Solutions; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Occurrence of disseminated intravascular coagulation (DIC) in active systemic anaphylaxis: role of platelet-activating factor.
Topics: Anaphylaxis; Animals; Azepines; Disseminated Intravascular Coagulation; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Triazoles | 1995 |
Role of interleukin-5 in enhanced migration of eosinophils from airways of immunized guinea-pigs.
Topics: Animals; Antibodies, Monoclonal; Antigens; Bronchoalveolar Lavage Fluid; Cell Movement; Eosinophils; Guinea Pigs; Immunization; Interleukin-5; Leukotriene B4; Male; Nedocromil; Ovalbumin; Platelet Activating Factor | 1994 |
Methoctramine induces nonspecific airway hyperresponsiveness in vivo.
Topics: Aerosols; Albuterol; Animals; Arachidonic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Diamines; Drug Synergism; Gallamine Triethiodide; Guinea Pigs; Histamine; Male; Muscarinic Antagonists; Ovalbumin; Parasympatholytics; Piperazines; Piperidines; Platelet Activating Factor; Propranolol; Receptors, Muscarinic | 1994 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
Modulation of the enhanced migration of eosinophils from the airways of sensitized guinea pigs: role of IL-5.
Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Immunization; Interleukin-5; Leukotriene B4; Male; Ovalbumin; Platelet Activating Factor | 1994 |
Role of eosinophil activation in the bronchial reactivity of allergic guinea pigs.
Topics: Animals; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Leukotriene B4; Male; Methacholine Chloride; Ovalbumin; Peroxidases; Platelet Activating Factor; Proteins; Respiratory Hypersensitivity; Ribonucleases | 1994 |
The effect of heparin and related proteoglycans on allergen and PAF-induced eosinophil infiltration.
Topics: Aerosols; Allergens; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chondroitin Sulfates; Dermatan Sulfate; Eosinophils; Glycosaminoglycans; Guinea Pigs; Heparin; Heparitin Sulfate; Male; Ovalbumin; Platelet Activating Factor; Proteoglycans | 1993 |
Adenosine-induced bronchoconstriction in conscious hyperresponsive and sensitized guinea pigs.
Topics: Adenosine; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Carbachol; Guinea Pigs; Immunization; Male; Ovalbumin; Ozone; Platelet Activating Factor | 1994 |
Interference of PCA 4248, a novel PAF receptor antagonist, with antigen-induced paw edema in mice.
Topics: Animals; Dihydropyridines; Edema; Injections, Intraperitoneal; Male; Mice; Ovalbumin; Platelet Activating Factor | 1993 |
Role of PAF in the allergic pleurisy caused by ovalbumin in actively sensitized rats.
Topics: Analysis of Variance; Animals; Azepines; Chemotactic Factors, Eosinophil; Diterpenes; Drug Hypersensitivity; Eosinophils; Female; Freund's Adjuvant; Ginkgolides; Inflammation; Lactones; Leukocyte Count; Male; Oligopeptides; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Role of neurogenic inflammation in antigen-induced vascular extravasation in guinea pig trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Capillary Permeability; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Trachea | 1993 |
[Bioassay of Lyso-PAF platelet activating factor and it's role in bronchial asthma].
Topics: Adolescent; Adult; Animals; Asthma; Biological Assay; Female; Guinea Pigs; Humans; Lung; Male; Middle Aged; Ovalbumin; Platelet Activating Factor; Thromboxane B2 | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Antigen-mediated pulmonary eosinophilia in immunoglobulin G1-sensitized guinea pigs: eosinophil peroxidase as a simple specific marker for detecting eosinophils in bronchoalveolar lavage fluid.
Topics: Animals; Antigens; Biomarkers; Bronchoalveolar Lavage Fluid; Eosinophil Peroxidase; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Leukocytes; Ovalbumin; Peroxidases; Platelet Activating Factor; Pulmonary Eosinophilia | 1993 |
Involvement of platelet-activating factor in death following anaphylactic shock in boosted and in unboosted mice.
Topics: Anaphylaxis; Animals; Azepines; Immunization, Secondary; Immunoglobulin E; Immunoglobulin G; Male; Mice; Ovalbumin; Platelet Activating Factor; Triazoles; Vaccination | 1993 |
The modulatory effect of antigen- and PAF-induced asthmatic reaction by aerosol administration of OKY-046 in guinea pigs.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Male; Methacrylates; Ovalbumin; Platelet Activating Factor; Thromboxane-A Synthase; Time Factors | 1995 |
Role of lipoxygenase metabolites in platelet-activating factor- and antigen-induced bronchial hyperresponsiveness and eosinophil infiltration.
Topics: Animals; Benzofurans; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; Humans; Leukotriene Antagonists; Lipoxygenase; Lipoxygenase Inhibitors; Male; Ovalbumin; Platelet Activating Factor; Pulmonary Eosinophilia; Quinolines | 1995 |
Effect of benzodiazepine on antigen-induced eosinophil infiltration into guinea pig conjunctiva.
Topics: Animals; Antigens; Benzodiazepines; Conjunctiva; Conjunctivitis, Allergic; Eosinophils; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor | 1996 |
Effect of SR 27417, a novel PAF antagonist on antigen-induced hypotension in the rat.
Topics: Animals; Antigens; Hypotension; Male; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
[The inhibitory effect of LTB4 antagonist on eosinophil infiltration in cutaneous and gut late phase response in BALB/C mice sensitized with ovalubumin (OVA)].
Topics: Animals; Cell Movement; Dermatitis, Atopic; Eosinophils; Female; Immunization; Immunosuppressive Agents; Intestines; Leukotriene B4; Mice; Mice, Inbred BALB C; Ovalbumin; Phenylpropionates; Platelet Activating Factor; Skin; Thiazoles | 1997 |
Effects of the platelet activating factor antagonists BN 52021 and BN 50730 on antigen-induced bronchial hyperresponsiveness and eosinophil infiltration in lung from sensitized guinea-pigs.
Topics: Acetylcholine; Aerosols; Animals; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Diterpenes; Eosinophilia; Ginkgo biloba; Ginkgolides; Guinea Pigs; Lactones; Leukotriene B4; Lung Diseases; Male; Molecular Structure; Ovalbumin; Plants, Medicinal; Platelet Activating Factor; Specific Pathogen-Free Organisms; Thienopyridines; Triazoles | 1993 |
Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice.
Topics: Administration, Oral; Anaphylaxis; Animals; Body Weight; Disease Models, Animal; Female; Fever; Food Hypersensitivity; Histamine; Injections, Intraperitoneal; Interferon-gamma; Interleukin-4; Mast Cells; Mice; Mice, Mutant Strains; Organ Size; Ovalbumin; Platelet Activating Factor; Th2 Cells | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
Protective effect of silymarin in antigen challenge- and histamine-induced bronchoconstriction in in vivo guinea-pigs.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Protective Agents; Silymarin; Substance P; Time Factors | 2002 |
Platelet-activating factor drives eotaxin production in an allergic pleurisy in mice.
Topics: Animals; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleura; Pleurisy; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 2002 |
Mast cells are required for experimental oral allergen-induced diarrhea.
Topics: Allergens; Anaphylaxis; Animals; Chymases; Diarrhea; Eosinophils; Immunoglobulin E; Intestinal Mucosa; Mast Cells; Mastocytosis; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Permeability; Platelet Activating Factor; Serine Endopeptidases; Serotonin; Th2 Cells | 2003 |
Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs.
Topics: Administration, Topical; Animals; Azepines; Chronic Disease; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Male; Ophthalmic Solutions; Ovalbumin; Platelet Activating Factor; Tears; Triazoles | 2004 |
Anti-allergic properties of the bromeliaceae Nidularium procerum: inhibition of eosinophil activation and influx.
Topics: Animals; Anti-Allergic Agents; Asthma; Bromeliaceae; Bronchoalveolar Lavage Fluid; Cell Movement; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Female; Inclusion Bodies; Inflammation Mediators; Interleukin-13; Lipid Metabolism; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Ovalbumin; Plant Extracts; Plant Leaves; Platelet Activating Factor; Pleurisy; Pulmonary Eosinophilia; Spleen; Time Factors | 2005 |
Involvement of platelet-activating factor and leukotrienes in anaphylactic segmental venoconstriction in ovalbumin sensitized guinea pig livers.
Topics: Animals; Chromones; Guinea Pigs; Leukotrienes; Liver; Male; Organ Size; Ovalbumin; Platelet Activating Factor; Vasoconstriction; Veins | 2005 |
Pharmacokinetic analysis of platelet-activating factor in the tears of guinea pigs with allergic conjunctivitis.
Topics: Animals; Conjunctivitis, Allergic; Eye; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Tears; Time Factors | 2006 |
A simple preparation method for mouse eosinophils and their responses to anti-allergic drugs.
Topics: Animals; Anti-Allergic Agents; Cell Movement; Cell Separation; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Eosinophils; Female; Interleukin-5; Leukotriene C4; Mice; Mice, Inbred BALB C; Ovalbumin; Phenotype; Platelet Activating Factor | 2007 |
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Topics: Animals; Antihypertensive Agents; Bronchial Hyperreactivity; Carbachol; Endothelin B Receptor Antagonists; Endothelin-1; Endothelins; Male; Mice; Mice, Inbred BALB C; Oligopeptides; Ovalbumin; Peptide Fragments; Phospholipid Ethers; Piperidines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptor, Endothelin B; Thromboxane A2 | 2007 |
Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis.
Topics: Allergens; Anaphylaxis; Animals; Basophils; Immunoglobulin E; Immunoglobulin G; Macrophages; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Ovalbumin; Platelet Activating Factor; Receptors, IgG; Signal Transduction | 2008 |
High dose of lipopolysaccharide pre-treatment prevents OVA-induced anaphylactic decreases in rectal temperature in the immunized mice.
Topics: Allergens; Anaphylaxis; Animals; Antibody Formation; Body Temperature; Histamine; Immunization; Immunoglobulin E; Immunoglobulin G; Lipopolysaccharides; Male; Mice; Ovalbumin; Platelet Activating Factor; Rectum | 2008 |
PAF, rather than histamine, participates in mouse anaphylactic hypotension.
Topics: Anaphylaxis; Animals; Blood Pressure; Diphenhydramine; Histamine; Histamine H1 Antagonists; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Receptors, Histamine H1 | 2008 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Leukotriene B4; Male; Mast Cells; Ovalbumin; Peritoneal Cavity; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 2010 |
Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine.
Topics: Anaphylaxis; Animals; Arterial Pressure; Cardiac Output; Diphenhydramine; Hemodynamics; Histamine; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Vascular Resistance; Vasoconstriction; Vasodilation | 2014 |
Clinacanthus nutans aqueous leaves extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Histamine; Immunoglobulin E; Immunoglobulin G; Interleukin-4; Interleukin-6; Mast Cells; Mice; Mice, Inbred C57BL; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2023 |