Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ono 1078

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with ono 1078 in 12 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(ono 1078)
Trials
(ono 1078)
Recent Studies (post-2010) (ono 1078)
9,1561875523705973

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)ono 1078 (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)2.7
Bile salt export pumpHomo sapiens (human)2.97
CruzipainTrypanosoma cruzi7
Cysteinyl leukotriene receptor 1Cavia porcellus (domestic guinea pig)0.001
Cysteinyl leukotriene receptor 2Homo sapiens (human)1.8105
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.003

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kimura, K; Mochizuki, K; Ohta, M; Shiota, M; Sugano, T1
Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T1
Goto, F; Yoshikawa, D1
Haranaka, K; Haranaka, R; Iimura, F; Sakurai, A; Satomi, N1
Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S1
Itoh, M; Joh, T; Katoh, N; Yokoyama, Y1
Misawa, M; Sugiyama, Y1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Fukuchi, Y; Ishii, S; Katayama, H; Nagase, T; Ouchi, Y; Shimizu, T1
Fujiu, T; Kato, M; Kimura, H; Morikawa, A; Suzuki, M1
Hagiwara, K; Kanazawa, M; Kikuchi, I; Nagata, M; Saito, K1
Cui, S; Kurata, Y; Liu, W; Ruan, Z; Shibamoto, T1

Other Studies

12 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ono 1078

ArticleYear
Different preparations of zymosan induce glycogenolysis independently in the perfused rat liver. Involvement of mannose receptors, peptide-leukotrienes and prostaglandins.
    The Biochemical journal, 1992, May-01, Volume: 283 ( Pt 3)

    Topics: Animals; Chromones; Glycogen; Hot Temperature; Ibuprofen; Isoproterenol; Liver; Male; Mannans; Masoprocol; Opsonin Proteins; Platelet Activating Factor; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Solubility; Zymosan

1992
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
    Agents and actions, 1992, Volume: 36, Issue:3-4

    Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles

1992
Effect of platelet-activating factor antagonist and leukotriene antagonist on endotoxin shock in the rat: role of the leukocyte.
    Circulatory shock, 1992, Volume: 38, Issue:1

    Topics: Animals; Chromones; Leukocyte Count; Leukocytes; Leukotriene Antagonists; Male; Neutropenia; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Vinblastine

1992
Preventive effect of several drugs against Pseudomonas aeruginosa infection and the toxicity of combined tumor necrosis factor with lipopolysaccharide: relationship between lethality and the arachidonic cascade.
    Biotherapy (Dordrecht, Netherlands), 1990, Volume: 2, Issue:3

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arachidonic Acid; Arachidonic Acids; Cephamycins; Chromones; Drug Synergism; Drugs, Chinese Herbal; Female; Leukotriene Antagonists; Leukotriene E4; Lipopolysaccharides; Mice; Mice, Inbred Strains; Platelet Activating Factor; Polymyxin B; Pseudomonas Infections; Recombinant Proteins; SRS-A; Tumor Necrosis Factor-alpha

1990
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:2

    Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2

1994
[Evaluation of the mechanism of endothelin-induced rat gastric mucosal lesion formation].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1994, Volume: 91, Issue:1

    Topics: Animals; Calcium; Chromones; Diltiazem; Endothelins; Gastric Mucosa; Leukotrienes; Male; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; SRS-A

1994
An airway hyperresponsiveness model in rat allergic asthma.
    Arerugi = [Allergy], 1993, Volume: 42, Issue:2

    Topics: Acetylcholine; Animals; Ascaris; Asthma; Bronchial Hyperreactivity; Capillary Permeability; Chromones; Depression, Chemical; Dinitrophenols; Disease Models, Animal; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; SRS-A; Thromboxane-A Synthase; Tissue Extracts

1993
Effects of Y-24180, a long-acting and potent antagonist to platelet-activating factor, on immediate asthmatic response in guinea pigs.
    Pharmacology, 1997, Volume: 54, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchodilator Agents; Chromones; Drug Interactions; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Male; Methacrylates; Platelet Activating Factor; Theophylline; Triazoles

1997
Airway responsiveness in transgenic mice overexpressing platelet-activating factor receptor. Roles of thromboxanes and leukotrienes.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:5

    Topics: Animals; Azepines; Bronchi; Bronchial Hyperreactivity; Chromones; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Methacrylates; Mice; Mice, Transgenic; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Thromboxanes; Triazoles

1997
Inhibition of human eosinophil activation by a cysteinyl leukotriene receptor antagonist (pranlukast; ONO-1078).
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2003, Volume: 40, Issue:4

    Topics: Cell Degranulation; Chromones; Eosinophils; Humans; Immunity, Cellular; Leukotriene Antagonists; Leukotriene D4; Macrophage-1 Antigen; Membrane Proteins; Phorbol Esters; Platelet Activating Factor; Receptors, Leukotriene; Superoxides

2003
Effect of the cysteinyl leukotriene antagonist pranlukast on transendothelial migration of eosinophils.
    International archives of allergy and immunology, 2005, Volume: 137 Suppl 1

    Topics: Adult; Cell Movement; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Chromones; Drug Interactions; Endothelial Cells; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Platelet Activating Factor; Receptors, Leukotriene

2005
Involvement of platelet-activating factor and leukotrienes in anaphylactic segmental venoconstriction in ovalbumin sensitized guinea pig livers.
    Prostaglandins & other lipid mediators, 2005, Volume: 78, Issue:1-4

    Topics: Animals; Chromones; Guinea Pigs; Leukotrienes; Liver; Male; Organ Size; Ovalbumin; Platelet Activating Factor; Vasoconstriction; Veins

2005