Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and omega-n-methylarginine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with omega-n-methylarginine in 27 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(omega-n-methylarginine)
Trials
(omega-n-methylarginine)
Recent Studies (post-2010) (omega-n-methylarginine)
9,1561875524,411344336

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)omega-n-methylarginine (IC50)
Neutrophil elastaseHomo sapiens (human)0.3
Proteinase-activated receptor 1Homo sapiens (human)0.0018
Nitric oxide synthase, endothelialBos taurus (cattle)7
Nitric oxide synthase, endothelialHomo sapiens (human)2.9489
Nitric oxide synthase, brainHomo sapiens (human)3.3983
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)7.5
Nitric oxide synthase, inducibleMus musculus (house mouse)2.3
Nitric oxide synthase, inducibleHomo sapiens (human)2.9252
Collagenase 3Homo sapiens (human)0.3
Nitric oxide synthase, brainMus musculus (house mouse)4.3

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (66.67)18.2507
2000's9 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boughton-Smith, NK; Deakin, AM; Whittle, BJ1
de Nucci, G; Mitchell, JA; Vane, JR; Warner, TD1
Shiga, T; Yoshikawa, D1
Bailly, C; Imbert-Teboul, M; Néant, F1
Alonso, A; Bosca, L; Crespo, MS; Garcia Rodriguez, MC; Steil, AA1
Adler, KB; Choe, NH; Fischer, BM; Li, H; Wright, DT1
Martin, D; Nadler, JV; Peterson, CL; Thompson, MA1
Caplan, MS; Hedlund, E; Hill, N; MacKendrick, W1
Filep, JG; Földes-Filep, E1
Green, PG; Heller, PH; Levine, JD; Luo, J1
Durán, WN; Fallek, SR; Hobson, RW; Noel, AA1
Durán, WN; Kim, D; Minnicozzi, M; Oshiro, H; Quardt, SM; Ramírez, MM1
Handa, RK; Strandhoy, JW1
Howard, KM; Mustafa, SB; Olson, MS1
Bindoni, M; Cardile, V; Jiang, X; Renis, M1
Baskin, SI; Lempka, JC; Nealley, EW1
Berón de Astrada, M; Chaud, MA; Franchi, AM; Gimeno, MF1
Kula, P; Kurmanowska, Z; Nowak, D; Stolarek, R1
Ahmed, A; Ahmed, Z; Dearn, S; Eggo, MC; Lewis, A; Rahman, M1
Foreman, JC; Maggs, JR; Turner, PJ1
Calcerrada, MC; Catalan, RE; Martinez, AM1
Bussolati, B; Camussi, G; Mariano, F; Migliori, M1
Bussolati, B; Camussi, G; Mariano, F; Migliori, M; Russo, S; Triolo, G1
Castranova, V; He, P; Schwegler-Berry, D; Zhu, L1
Alloatti, G; Altruda, F; Azzolino, O; Barberis, L; Bedendi, I; Bosco, O; Del Sorbo, L; Hirsch, E; Levi, R; Malan, D; Marcantoni, A; Montrucchio, G; Penna, C; Wymann, M1
Slomiany, A; Slomiany, BL1
He, P; Zhu, L1

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and omega-n-methylarginine

ArticleYear
Induction by inhibitors of nitric oxide synthase of hyperresponsiveness in the human nasal airway.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Bronchial Hyperreactivity; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Humans; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Receptor, Bradykinin B2

2000

Other Studies

26 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and omega-n-methylarginine

ArticleYear
Actions of nitric oxide on the acute gastrointestinal damage induced by PAF in the rat.
    Agents and actions, 1992, Volume: Spec No

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Capillary Permeability; Endotoxins; Escherichia coli; Intestine, Small; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Platelet Activating Factor; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Stomach; Vasodilator Agents

1992
Alkaline buffers release EDRF from bovine cultured aortic endothelial cells.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Animals; Arginine; Buffers; Cattle; Cells, Cultured; Cyclohexanones; Endothelium, Vascular; Epoprostenol; Hydrogen-Ion Concentration; Lipoprotein Lipase; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Pyrimidinones; Thiazoles

1991
Platelet-activating factor-induced loss of vascular responsiveness to noradrenaline in pithed rats: involvement of nitric oxide.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: Analysis of Variance; Animals; Arginine; Cyclooxygenase Inhibitors; Decerebrate State; Enzyme Inhibitors; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar; Vasomotor System

1995
Cyclic guanosine monophosphate is the mediator of platelet-activating factor inhibition on transport by the mouse kidney thick ascending limb.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Kidney Medulla; Kinetics; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Parathyroid Hormone; Platelet Activating Factor; Protein Kinase C; Time Factors; Vasopressins

1994
Platelet-activating factor: the effector of protein-rich plasma extravasation and nitric oxide synthase induction in rat immune complex peritonitis.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Antibody Formation; Arginine; Arthus Reaction; Blotting, Northern; Cells, Cultured; Enzyme Induction; Extravasation of Diagnostic and Therapeutic Materials; Leucine; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; Peritonitis; Phagocytes; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Specific Pathogen-Free Organisms

1995
Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase.
    American journal of respiratory cell and molecular biology, 1995, Volume: 13, Issue:5

    Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Histamine; Inflammation Mediators; Mucins; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Secretory Rate; Superoxides; Trachea; Tumor Necrosis Factor-alpha

1995
Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism.
    Journal of neurochemistry, 1995, Volume: 64, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Aspartic Acid; Female; Flavanones; Flavonoids; gamma-Aminobutyric Acid; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Indomethacin; Masoprocol; omega-N-Methylarginine; Platelet Activating Factor; Potassium; Prostaglandin-Endoperoxide Synthases; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Taurine

1995
The role of endogenous nitric oxide and platelet-activating factor in hypoxia-induced intestinal injury in rats.
    Gastroenterology, 1994, Volume: 106, Issue:2

    Topics: Animals; Arginine; Hypoxia; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1994
Modulation by nitric oxide of platelet-activating factor-induced albumin extravasation in the conscious rat.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Albumins; Animals; Arginine; Blood Pressure; Capillary Permeability; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar

1993
Neurogenic and non-neurogenic mechanisms of plasma extravasation in the rat.
    Neuroscience, 1993, Volume: 52, Issue:3

    Topics: Animals; Arginine; Blood Physiological Phenomena; Bradykinin; Dose-Response Relationship, Drug; Joints; Male; Models, Biological; omega-N-Methylarginine; Oxidopamine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Time Factors

1993
Inhibition of nitric oxide synthase attenuates primed microvascular permeability in the in vivo microcirculation.
    Journal of vascular surgery, 1995, Volume: 22, Issue:6

    Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Cromolyn Sodium; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Histamine; Inflammation; Macrophage-1 Antigen; Male; Mast Cells; Mesocricetus; Microcirculation; Microscopy, Video; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor

1995
Platelet activating factor modulates microvascular permeability through nitric oxide synthesis.
    Microvascular research, 1995, Volume: 50, Issue:2

    Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Male; Mesocricetus; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Signal Transduction

1995
Nitric oxide mediates the inhibitory action of platelet-activating factor on angiotensin II-induced renal vasoconstriction, in vivo.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Kidney; Linear Models; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar; Vasoconstriction

1996
Platelet-activating factor augments lipopolysaccharide-induced nitric oxide formation by rat Kupffer cells.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:6

    Topics: Animals; Arginine; Biological Transport, Active; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Kinetics; Kupffer Cells; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Shock, Septic

1996
Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero- 3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytes.
    Brain research, 1996, Apr-09, Volume: 715, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Astrocytes; Azepines; Cells, Cultured; Citrulline; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Thienopyridines; Triazoles

1996
The effects of EDRF/NO releasers or calcium ionophore A23187 on cyanide toxicity in mice.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:2

    Topics: Animals; Bradykinin; Calcimycin; Carbachol; Cyanides; Hydralazine; Ionophores; Lethal Dose 50; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Seizures; Substance P; Survival Rate

1996
Nitric oxide mediates platelet-activating factor stimulatory action on uterine prostaglandin production.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:1

    Topics: Animals; Arachidonic Acid; Citrulline; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; Enzyme Inhibitors; Female; Gestational Age; Indomethacin; Isometric Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Pregnancy; Prostaglandins; Rats; Rats, Wistar; Uterus

1998
Effect of various agonists on nitric oxide generation by human polymorphonuclear leukocytes.
    International journal of clinical & laboratory research, 1998, Volume: 28, Issue:2

    Topics: Concanavalin A; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1998
Activation of platelet-activating factor (PAF) receptor stimulates nitric oxide (NO) release via protein kinase C-alpha in HEC-1B human endometrial epithelial cell line.
    Molecular medicine (Cambridge, Mass.), 2000, Volume: 6, Issue:1

    Topics: Azepines; Calcium; Cell Line; Endometrium; Enzyme Activation; Epithelial Cells; Female; Humans; Indoles; Infertility, Female; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Kinase C-alpha; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2000
PAF-stimulated protein tyrosine phosphorylation in hippocampus: involvement of NO synthase.
    Neurochemical research, 2002, Volume: 27, Issue:4

    Topics: Animals; Hippocampus; In Vitro Techniques; Kinetics; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Rats; Rats, Wistar

2002
Nitric oxide/platelet activating factor cross-talk in mesangial cells modulates the interaction with leukocytes.
    Kidney international, 2002, Volume: 62, Issue:4

    Topics: Cell Adhesion; Cell Communication; Cells, Cultured; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Kidney Glomerulus; Leukocytes, Mononuclear; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor

2002
Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Adult; Arginine; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Humans; Lipopolysaccharides; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Stereoisomerism; Tumor Necrosis Factor-alpha

2003
Internalization of caveolin-1 scaffolding domain facilitated by Antennapedia homeodomain attenuates PAF-induced increase in microvessel permeability.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:1

    Topics: Animals; Antennapedia Homeodomain Protein; Capillary Permeability; Caveolin 1; Caveolins; Endothelium, Vascular; Enzyme Inhibitors; Female; Homeodomain Proteins; Microcirculation; Microscopy, Electron; Microscopy, Fluorescence; Nuclear Proteins; omega-N-Methylarginine; Platelet Activating Factor; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Transcription Factors

2004
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility.
    Cardiovascular research, 2003, Nov-01, Volume: 60, Issue:2

    Topics: Animals; Azepines; Class Ib Phosphatidylinositol 3-Kinase; Female; In Vitro Techniques; Isoenzymes; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2003
Platelet-activating factor mediates Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis via phosphatidylinositol 3-kinase-dependent constitutive nitric-oxide synthase activation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:1 Pt 1

    Topics: Amidines; Androstadienes; Animals; Apoptosis; Benzylamines; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgolides; Glucosamine; Lactones; Lipopolysaccharides; Mucins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Sublingual Gland; Tritium; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin

2004
Platelet-activating factor increases endothelial [Ca2+]i and NO production in individually perfused intact microvessels.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6

    Topics: Animals; Calcium; Cytoplasm; Endothelium, Vascular; Mesenteric Veins; Microcirculation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Rats; Venules

2005