Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and oleic acid

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with oleic acid in 18 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(oleic acid)
Trials
(oleic acid)
Recent Studies (post-2010) (oleic acid)
9,1561875528,7682483,051

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)oleic acid (IC50)
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)6.2

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's9 (50.00)18.2507
2000's4 (22.22)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekholm, J; Hanahan, DJ; Javors, MA; Kimoto, M; Siafaka-Kapadai, A1
Blank, ML; Fitzgerald, V; Lee, TC; Malone, B; Snyder, F1
Gandhi, C; Hanahan, DJ; Nunez, D; Olson, MS; Randon, J; Siafaka-Kapadai, A1
Adi, S; Feingold, KR; Fiers, W; Grunfeld, C; Moser, A; Soued, M1
Houben, A; Lenoir, G; Remacle, J; Remy, E; Vandesteene, C1
McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA1
Blank, ML; Cress, EA; Lee, YJ; Snyder, F1
Auclair, M; Mazière, C; Mazière, JC; Mora, L; Polonovski, J1
Arnould, T; Michiels, C; Remacle, J1
Arnould, T; Delaive, E; Janssens, D; Michiels, C; Remacle, J1
Evans, RD; Wang, X1
Aihara, M; Ishii, S; Kume, K; Mishina, M; Shimizu, T; Tabuchi, S1
Chang, H; Roy Baker, R1
Baker, RR; Chang, HY1
Geiser, T1
Chen, DL; Hill, LL; Kozlowski, J; Schuster, DP1
He, JL; Lu, J; Xu, GL; Yu, SQ; Zhang, LL; Zhou, M1
Faxvaag, A; Feuerherm, AJ; Johansen, B; Leistad, L1

Other Studies

18 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and oleic acid

ArticleYear
Dual effects of oleic acid on Ca2+ mobilization and protein phosphorylation in human platelets in presence or absence of platelet activating factor.
    Archives of biochemistry and biophysics, 1992, Nov-01, Volume: 298, Issue:2

    Topics: Blood Platelets; Blood Proteins; Calcium; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Kinetics; Manganese; Molecular Weight; Oleic Acid; Oleic Acids; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Platelet Aggregation; Spectrometry, Fluorescence; Tyrosine

1992
Regulation of the synthesis of platelet-activating factor and its inactive storage precursor (1-alkyl-2-acyl-sn-glycero-3-phosphocholine) from 1-alkyl-2-acetyl-sn-glycerol by rabbit platelets.
    The Journal of biological chemistry, 1990, Jun-05, Volume: 265, Issue:16

    Topics: Animals; Blood Platelets; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Dithiothreitol; Glyceryl Ethers; Kinetics; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Platelet Activating Factor; Rabbits; Type C Phospholipases

1990
The inhibition of platelet-activating factor-induced platelet activation by oleic acid is associated with a decrease in polyphosphoinositide metabolism.
    The Journal of biological chemistry, 1990, Oct-25, Volume: 265, Issue:30

    Topics: Animals; Blood Platelets; Blood Proteins; In Vitro Techniques; Inositol Phosphates; Oleic Acid; Oleic Acids; Phosphatidic Acids; Phosphatidylinositols; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin

1990
Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Animals; Aspirin; Azepines; Cholesterol; Fatty Acids; Ibuprofen; Interleukin-6; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oleic Acid; Oleic Acids; Pentoxifylline; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Triazoles; Triglycerides; Tumor Necrosis Factor-alpha

1990
Inhibition of platelet-activating factor biosynthesis via the acetyltransferase by arachidonic and oleic acids in ionophore A23187-stimulated bovine neutrophils.
    Biochimica et biophysica acta, 1989, Sep-11, Volume: 1005, Issue:1

    Topics: Acetates; Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; In Vitro Techniques; Kinetics; Neutrophils; Oleic Acid; Oleic Acids; Platelet Activating Factor

1989
Phospholipid remodeling in human neutrophils. Parallel activation of a deacylation/reacylation cycle and platelet-activating factor synthesis.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Acylation; Calcimycin; Fatty Acids, Nonesterified; Glycerol; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipids; Platelet Activating Factor

1989
Stimulation of the de novo pathway for the biosynthesis of platelet-activating factor (PAF) via cytidylyltransferase activation in cells with minimal endogenous PAF production.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Animals; Carcinoma, Ehrlich Tumor; Choline-Phosphate Cytidylyltransferase; Chromatography, High Pressure Liquid; Enzyme Activation; Glyceryl Ethers; Kinetics; Mice; Microsomes; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phenylmethylsulfonyl Fluoride; Phosphatidylcholines; Platelet Activating Factor; Tumor Cells, Cultured

1988
PAF-acether decreases low density lipoprotein degradation and alters lipid metabolism in cultured human fibroblasts.
    FEBS letters, 1988, Aug-15, Volume: 236, Issue:1

    Topics: Cells, Cultured; Cholesterol Esters; Fibroblasts; Humans; Lipids; Lipoproteins, LDL; Oleic Acid; Oleic Acids; Phospholipids; Platelet Activating Factor; Sterols; Triglycerides

1988
Increased PMN adherence on endothelial cells after hypoxia: involvement of PAF, CD18/CD11b, and ICAM-1.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1

    Topics: Antibodies, Monoclonal; Antigens, CD; Azepines; Biological Assay; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Hypoxia; Cells, Cultured; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Kinetics; Neutrophils; Oleic Acid; Oleic Acids; Platelet Activating Factor; Recombinant Proteins; Stearic Acids; Time Factors; Triazoles; Umbilical Veins

1993
Hypoxia induces PMN adherence to umbilical vein endothelium.
    Cardiovascular research, 1995, Volume: 30, Issue:6

    Topics: Antibodies, Monoclonal; Azepines; Cell Adhesion; Culture Techniques; Endothelium, Vascular; Humans; Hypoxia; Intercellular Adhesion Molecule-1; Microscopy, Electron, Scanning; Neutrophil Activation; Neutrophils; Oleic Acid; Oleic Acids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Umbilical Veins

1995
Effect of endotoxin and platelet-activating factor on lipid oxidation in the rat heart.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:7

    Topics: Animals; Escherichia coli; Hemodynamics; Lipid Metabolism; Lipopolysaccharides; Lipoprotein Lipase; Male; Myocardium; Oleic Acid; Oxidation-Reduction; Platelet Activating Factor; Rats; Rats, Wistar; Triolein

1997
Lipid mediators modulate NMDA receptor currents in a Xenopus oocyte expression system.
    Neuroscience letters, 1997, Nov-14, Volume: 237, Issue:1

    Topics: Animals; Arachidonic Acid; Lipids; Lysophospholipids; Mice; Oleic Acid; Oocytes; Phosphorylation; Platelet Activating Factor; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus laevis

1997
Substrate specificities of neuronal nuclear acetyltransferases involved in the synthesis of platelet-activating factor: differences in the use of 1-alkyl and 1-acyl lysophospholipid acceptors.
    Biochimica et biophysica acta, 1998, Feb-16, Volume: 1390, Issue:2

    Topics: Acetylation; Acetyltransferases; Acyl Coenzyme A; Animals; Brain; Cell Nucleus; Glycerophosphates; Kinetics; Lysophosphatidylcholines; Lysophospholipids; Neurons; Nuclear Envelope; Nuclear Proteins; Oleic Acid; Platelet Activating Factor; Rabbits; Substrate Specificity

1998
The regulation of CoA-independent transacylation reactions in neuronal nuclei by lysophospholipid, free fatty acid, and lysophospholipase: the control of nuclear lyso platelet-activating factor metabolism.
    Molecular and cellular biochemistry, 2000, Volume: 215, Issue:1-2

    Topics: Acylation; Animals; Arachidonic Acids; Cattle; Cell Nucleus; Cerebral Cortex; Chromatography; Coenzyme A; Dose-Response Relationship, Drug; Fatty Acids; Ischemia; Lysophospholipase; Lysophospholipids; Microsomes; Models, Chemical; Neurons; Oleic Acid; Organophosphonates; Platelet Activating Factor; Rabbits; Swine

2000
The role of neutrophils and neutrophil products in pulmonary hemodynamics of endotoxin in oleic acid-induced lung injury.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Animals; Endotoxins; Lung Diseases; Neutrophils; Oleic Acid; Phospholipases A; Platelet Activating Factor; Pulmonary Circulation; Rats

2004
Neutrophils and neutrophil products do not mediate pulmonary hemodynamic effects of endotoxin on oleic acid-induced lung injury.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Animals; Body Water; Cardiac Output; CD18 Antigens; Dogs; Endotoxins; Enzyme Inhibitors; Indoles; Lung; Lung Diseases; Magnetic Resonance Imaging; Neutrophils; Oleic Acid; Oxygen Consumption; Phospholipases A; Platelet Activating Factor; Pulmonary Circulation; Regional Blood Flow; Tomography, Emission-Computed

2004
[Protective effect of rupatadine against oleic acid-induced acute lung injury in rabbits].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:3

    Topics: Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Cyproheptadine; Enzyme-Linked Immunosorbent Assay; Intercellular Adhesion Molecule-1; Interleukin-8; Lung; Male; Oleic Acid; Platelet Activating Factor; Protective Agents; Rabbits; Random Allocation; Respiratory Distress Syndrome

2007
Multiple phospholipase A2 enzymes participate in the inflammatory process in osteoarthritic cartilage.
    Scandinavian journal of rheumatology, 2011, Volume: 40, Issue:4

    Topics: Aged; Aged, 80 and over; Arachidonic Acid; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dinoprostone; Female; Humans; Inflammation; Interleukin-1beta; Isoenzymes; Male; Middle Aged; Oleic Acid; Osteoarthritis, Hip; Osteoarthritis, Knee; Phospholipases A2; Platelet Activating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha

2011