Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and nimesulide

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with nimesulide in 6 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(nimesulide)
Trials
(nimesulide)
Recent Studies (post-2010) (nimesulide)
9,1561875521,272200271

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)nimesulide (IC50)
MyeloperoxidaseHomo sapiens (human)2.1
Prostaglandin G/H synthase 1Ovis aries (sheep)6.2
Procathepsin LHomo sapiens (human)1.92
Leukotriene A-4 hydrolaseHomo sapiens (human)0.023
Prostaglandin G/H synthase 1Homo sapiens (human)2.493
Prostaglandin G/H synthase 2Homo sapiens (human)1.8947
Prostaglandin G/H synthase 2Ovis aries (sheep)1.16

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuijpers, TW; Roos, D; Tool, AT; Verhoeven, AJ1
Tool, AT; Verhoeven, AJ1
Knol, EF; Mul, FP; Roos, D; Tool, AT; Verhoeven, AJ1
Bazan, HE; Ottino, P1
Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N1
Ahmed, S; Dima, L; Gul, S; Moga, M; Ze Jaafar, H; Zia-Ul-Haq, M1

Other Studies

6 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and nimesulide

ArticleYear
Nimesulide inhibits platelet-activating factor synthesis in activated human neutrophils.
    Drugs, 1993, Volume: 46 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Aggregation; Cells, Cultured; Humans; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Sulfonamides

1993
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan

1995
The effect of salmeterol and nimesulide on chemotaxis and synthesis of PAF and LTC4 by human eosinophils.
    The European respiratory journal. Supplement, 1996, Volume: 22

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chemotaxis; Complement C5a; Cyclic AMP; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Guinea Pigs; Humans; Leukotriene C4; Platelet Activating Factor; Salmeterol Xinafoate; Sulfonamides

1996
Corneal stimulation of MMP-1, -9 and uPA by platelet-activating factor is mediated by cyclooxygenase-2 metabolites.
    Current eye research, 2001, Volume: 23, Issue:2

    Topics: Animals; Blotting, Western; Cornea; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Induction; Isoenzymes; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Nitrobenzenes; Organ Culture Techniques; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; Sulfonamides; Urokinase-Type Plasminogen Activator

2001
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
    Inflammation, 2002, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan

2002
Anti-platelet effects of nimesulide in isoproterenol-induced myocardial ischaemia and infarction in rabbits.
    Acta cardiologica, 2015, Volume: 70, Issue:4

    Topics: Animals; Disease Models, Animal; Isoproterenol; Myocardial Infarction; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Rabbits; Sulfonamides; Sympathomimetics; Treatment Outcome

2015