Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and nifedipine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with nifedipine in 13 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(nifedipine)
Trials
(nifedipine)
Recent Studies (post-2010) (nifedipine)
9,15618755216,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pugsley, MK; Salari, H; Walker, MJ1
Gandhi, CR; Olson, MS1
Bazill, GW; Dexter, TM1
Bevan, J; Heptinstall, S1
Bevan, J; Glusa, E; Heptinstall, S1
Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM1
Knee, CD; Krell, RD; Kusner, EJ1
Lad, N; Lunt, DO; McCullagh, KG; Tuffin, DP; Wade, PJ1
Clark, JS; Jubb, SN; Maloney, PJ; Young, JM1
Benveniste, J; Cerrina, J; Coëffier, E; Duroux, P; Jouvin-Marche, E1
Endo, C; Hoshi, K; Nakanishi, H; Okawa, T; Sato, A; Suzuki, H; Suzuki, Y1
Durán, WN; Hobson, RW; Kim, D; Kobayashi, I; Oshiro, H; Takenaka, H1
James, AN; Parkman, HP; Ryan, JP1

Other Studies

13 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and nifedipine

ArticleYear
Actions of platelet-activating factor on isolated rat hearts.
    Circulatory shock, 1991, Volume: 35, Issue:4

    Topics: Animals; Blood Flow Velocity; Dose-Response Relationship, Drug; Electrocardiography; Heart; Male; Myocardial Contraction; Nifedipine; Perfusion; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrodotoxin

1991
PAF effects on transmembrane signaling pathways in rat Kupffer cells.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Bradykinin; Calcium; Cell Membrane; Cells, Cultured; Cholera Toxin; Egtazic Acid; Inositol Phosphates; Kupffer Cells; Liver; Male; Models, Biological; Nifedipine; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Platelet Activating Factor; Prostaglandins; Rats; Rats, Inbred Strains; Signal Transduction; Vasopressins; Virulence Factors, Bordetella

1991
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil

1990
How can we inhibit 5-HT-induced platelet aggregation and why should we bother?
    Folia haematologica (Leipzig, Germany : 1928), 1988, Volume: 115, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Amlodipine; Female; Humans; Male; Middle Aged; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Serotonin Antagonists; Verapamil

1988
Verapamil is a potent inhibitor of 5-HT-induced platelet aggregation.
    Thrombosis research, 1989, Jul-15, Volume: 55, Issue:2

    Topics: Adenosine Diphosphate; Amlodipine; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil

1989
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil

1989
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
    Agents and actions, 1987, Volume: 20, Issue:1-2

    Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles

1987
Effect of calcium and calcium antagonists on [3H]-Paf-acether binding to washed human platelets.
    Thrombosis research, 1986, Jan-15, Volume: 41, Issue:2

    Topics: Benzazepines; Blood Platelets; Buffers; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Male; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Statistics as Topic; Stereoisomerism; Tritium; Verapamil

1986
Pharmacological investigation of the mechanisms of platelet-activating factor induced mortality in the mouse.
    Prostaglandins, 1985, Volume: 30, Issue:4

    Topics: Anaphylaxis; Animals; Chloroquine; Chlortetracycline; Dexamethasone; Dose-Response Relationship, Drug; Female; Indomethacin; Injections, Intravenous; Male; Mice; Mice, Inbred DBA; Naproxen; Nicardipine; Nifedipine; Platelet Activating Factor; Pyrazoles; Quinacrine; Tetracycline; Verapamil

1985
Effect of the Ca2+ antagonist nifedipine on the release of platelet-activating factor (PAF-acether), slow-reacting substance and beta-glucuronidase from human neutrophils.
    European journal of pharmacology, 1983, Apr-22, Volume: 89, Issue:1-2

    Topics: Autacoids; Calcium; Calcium Channel Blockers; Glucuronidase; Humans; In Vitro Techniques; Neutrophils; Nifedipine; Platelet Activating Factor; Pyridines

1983
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor].
    Nihon Sanka Fujinka Gakkai zasshi, 1994, Volume: 46, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; Isoquinolines; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pregnancy; Pyridinium Compounds; Rats; Tetrahydroisoquinolines; Uterine Contraction

1994
L-type calcium channel blockers modulate the microvascular hyperpermeability induced by platelet-activating factor in vivo.
    Journal of vascular surgery, 1995, Volume: 22, Issue:6

    Topics: Animals; Calcium Channel Blockers; Capillary Permeability; Cricetinae; Dextrans; Fluorescein-5-isothiocyanate; Male; Mesocricetus; Nifedipine; Platelet Activating Factor; Spectrometry, Fluorescence; Vasoconstriction; Verapamil

1995
The contractile action of platelet-activating factor on gallbladder smooth muscle.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1

    Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Diterpenes; Dose-Response Relationship, Drug; Free Radical Scavengers; Gallbladder Emptying; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Muscle Contraction; Muscle, Smooth; Nifedipine; Pertussis Toxin; Platelet Activating Factor; Prostaglandins; Ryanodine; Vasodilator Agents; Virulence Factors, Bordetella

2000