Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ng-nitroarginine methyl ester

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with ng-nitroarginine methyl ester in 60 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010) (ng-nitroarginine methyl ester)
9,15618755212,6401172,342

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)2.6
Nitric oxide synthase, inducibleHomo sapiens (human)8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's37 (61.67)18.2507
2000's20 (33.33)29.6817
2010's3 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S1
Crook, P; May, GR; Moore, PK; Page, CP1
Barrachina, MD; Esplugues, JV; Martinez-Cuesta, MA; Piqué, JM; Whittle, BJ1
Butler, KD; Crook, P; May, GR; Page, CP; Paul, W1
Buckalew, VM; Handa, RK; Strandhoy, JW1
Bailly, C; Imbert-Teboul, M; Néant, F1
Durán, WN; Kim, D1
Fujii, E; Irie, K; Muraki, T; Ohba, K; Uchida, Y1
Alonso, A; Bosca, L; Crespo, MS; Garcia Rodriguez, MC; Steil, AA1
Anderson, DC; Granger, DN; Kubes, P; Kurose, I; Miyasaka, M; Paulson, J; Wolf, R1
Beierwaltes, WH; Carretero, OA; Potter, DL; Sigmon, DH1
Albertini, M; Clement, MG1
Berthiaume, N; Bkaily, G; Claing, A; D'Orléans-Juste, P; Rola-Pleszczynski, M; Sirois, P1
Befus, D; Kanwar, S; Kubes, P; Wallace, JL1
Caplan, M; Hsueh, W; MacKendrick, W1
Caplan, MS; Hedlund, E; Hill, N; MacKendrick, W1
Filep, JG; Földes-Filep, E1
Arndt, H; Granger, DN; Kubes, P; Kurose, I; Russell, JB1
Filep, JG; Földes-Filep, E; Sirois, P1
Durán, WN; Kim, D; Minnicozzi, M; Oshiro, H; Quardt, SM; Ramírez, MM1
Meijer, F; Ruijter, JM; Van Delft, JL; Van Haeringen, NJ1
Capasso, F; Gaginella, TS; Izzo, AA; Mascolo, N2
Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N1
Arima, S; Ito, S; Juncos, LA; Ren, Y1
Autunes, E; De Nucci, G; Ferreira, HH; Flores, CA; Lima, CS; Medeiros, MV; Sannomiya, P1
Ibbotson, G; Kubes, P; Niu, XF1
Coston, AF; Klabunde, RE; Laniyonu, AA1
Collins, LC; Roberts, AM1
Friebe, WG; Scheuer, W; Thierse, HJ; Tibes, U; Voelter, W1
Arese, M; Battaglia, E; Bussolino, F; Camussi, G; de Martino, A; Lupia, E; Montrucchio, G; Tizzani, A1
Koyama, S; Matsuda, Y; Shibamoto, T; Wang, HG1
Baydoun, AR; Cannon, TR; Mann, GE1
Araújo, CV; Catelli, M; Cordeiro, RS; Estato, V; Lopes-Martins, RA; Tibiriçá, E1
Fujii, E; Irie, K; Ishida, H; Muraki, T; Wada, K; Yoshioka, T1
Alloatti, G; Camussi, G; De Martino, A; Montrucchio, G; Penna, C1
Chłopicki, S; Olszanecki, R1
László, F; Morschl, E; Nemcsik, J; Pávó, I; Pozsár, J; Whittle, BJ1
Carratù, L; Faraone, S; Maniscalco, M; Sofia, M1
Foreman, JC; Maggs, JR; Turner, PJ1
Grassi, S; Pettorossi, VE1
Alloatti, G; Camussi, G; Mariano, F; Penna, C1
Akutsu, A; Hayakawa, S; Hirano, H; Imai, T; Ishii, K; Nakahara, T; Shigenobu, K; Tanaka, H; Tanaka, Y1
Balogh, I; Kecskeméti, V1
Hwang, EG; Jeon, SY; Jung, TG; Kim, EA; Kim, JP; Ma, YW1
Bussolati, B; Camussi, G; Mariano, F; Migliori, M1
Carratù, L; Ferrara, G; Maniscalco, M; Sofia, M1
Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG1
Bussolati, B; Camussi, G; Mariano, F; Migliori, M; Russo, S; Triolo, G1
Handa, RK; Handa, SE; Strandhoy, JW1
Alloatti, G; Altruda, F; Azzolino, O; Barberis, L; Bedendi, I; Bosco, O; Del Sorbo, L; Hirsch, E; Levi, R; Malan, D; Marcantoni, A; Montrucchio, G; Penna, C; Wymann, M1
Rhee, CK1
Bredt, DS; Hua, Z; Johns, RA; Tao, YX; Xu, Y; Zhang, B1
Chong, T; Ramirez, R; Victorino, GP1
Chang, KH; Jeon, EJ; Kim, DH; Lee, SK; Park, YS; Yeo, SW1
Brkovic, A; Sirois, MG1
Cui, S; Kurata, Y; Shibamoto, T; Takano, H; Zhao, Z1
De Nucci, G; Donato, JL; Lilla, S; Lorenzetti, R; Maziero, AM1
Asano, M; Cui, H; Du, W; Okamoto, Y; Shibamoto, T; Takuwa, N; Takuwa, Y; Yoshioka, K; Zhang, W1
Kuda, Y; Kurata, Y; Shibamoto, T; Song, J; Tanida, M; Wang, M; Zhang, T1

Reviews

1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ng-nitroarginine methyl ester

ArticleYear
Recent findings on the mode of action of laxatives: the role of platelet activating factor and nitric oxide.
    Trends in pharmacological sciences, 1998, Volume: 19, Issue:10

    Topics: Animals; Cathartics; Enzyme Inhibitors; Gastric Mucosa; Gastrointestinal Motility; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats

1998

Trials

2 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ng-nitroarginine methyl ester

ArticleYear
The effect of platelet-activating factor (PAF) on nasal airway resistance in healthy subjects is not mediated by nitric oxide.
    Allergy, 2000, Volume: 55, Issue:8

    Topics: Adult; Airway Resistance; Bradykinin; Double-Blind Method; Female; Humans; Male; Nasal Obstruction; Nasal Provocation Tests; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor

2000
Induction by inhibitors of nitric oxide synthase of hyperresponsiveness in the human nasal airway.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Bronchial Hyperreactivity; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Humans; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Receptor, Bradykinin B2

2000

Other Studies

57 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ng-nitroarginine methyl ester

ArticleYear
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar

1992
The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit.
    British journal of pharmacology, 1991, Volume: 102, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arginine; Cerebrovascular Circulation; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Pulmonary Circulation; Rabbits

1991
The role of nitric oxide and platelet-activating factor in the inhibition by endotoxin of pentagastrin-stimulated gastric acid secretion.
    European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Azepines; Endotoxins; Female; Gastric Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentagastrin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles

1992
The pharmacological modulation of thrombin-induced cerebral thromboembolism in the rabbit.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Animals; Anistreplase; Arginine; Blood Platelets; Diterpenes; Female; Fibrinogen; Fibrinolytic Agents; Ginkgolides; Hirudins; Injections, Intra-Arterial; Injections, Intravenous; Intracranial Embolism and Thrombosis; Lactones; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Polydeoxyribonucleotides; Rabbits; Recombinant Proteins; Thrombin

1992
Effects of phospholipids on renal function.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2

    Topics: Angiotensin II; Animals; Arginine; Diuresis; Dogs; Hemodynamics; Kidney; Lysophosphatidylcholines; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Platelet Activating Factor; Rats; Renal Artery; Renal Circulation; Structure-Activity Relationship; Vasodilation; Vasopressins

1993
Cyclic guanosine monophosphate is the mediator of platelet-activating factor inhibition on transport by the mouse kidney thick ascending limb.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Kidney Medulla; Kinetics; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Parathyroid Hormone; Platelet Activating Factor; Protein Kinase C; Time Factors; Vasopressins

1994
Platelet-activating factor stimulates protein tyrosine kinase in hamster cheek pouch microcirculation.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Capillary Permeability; Catechols; Cheek; Cricetinae; Genistein; Isoflavones; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Platelet Activating Factor; Protein-Tyrosine Kinases; Tyrphostins

1995
Role of eicosanoids but not nitric oxide in the platelet-activating factor-induced increase in vascular permeability in mouse skin.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Capillary Permeability; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Skin

1995
Platelet-activating factor: the effector of protein-rich plasma extravasation and nitric oxide synthase induction in rat immune complex peritonitis.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Antibody Formation; Arginine; Arthus Reaction; Blotting, Northern; Cells, Cultured; Enzyme Induction; Extravasation of Diagnostic and Therapeutic Materials; Leucine; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; Peritonitis; Phagocytes; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Specific Pathogen-Free Organisms

1995
Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage.
    Circulation research, 1993, Volume: 73, Issue:1

    Topics: Albumins; Animals; Arginine; Azepines; Blood Flow Velocity; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cyclic GMP; Intercellular Adhesion Molecule-1; Leukocytes; Male; NG-Nitroarginine Methyl Ester; P-Selectin; Phalloidine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Triazoles; Venules

1993
Nitric oxide synthesis inhibition blocks reversal of two-kidney, one clip renovascular hypertension after unclipping.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:2

    Topics: Animals; Arginine; Bradykinin; Hypertension, Renovascular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Renal Circulation

1995
In pigs, inhaled nitric oxide (NO) counterbalances PAF-induced pulmonary hypertension.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:5

    Topics: Administration, Inhalation; Animals; Arginine; Blood Pressure; Female; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pulmonary Artery; Swine; Vasoconstriction

1994
Role of R-type calcium channels in the response of the perfused arterial and venous mesenteric vasculature of the rat to platelet-activating factor.
    British journal of pharmacology, 1994, Volume: 112, Issue:4

    Topics: Animals; Arginine; Azepines; Calcium Channels; Isradipine; Male; Mesenteric Arteries; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Perfusion; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Wistar; Triazoles

1994
Nitric oxide synthesis inhibition increases epithelial permeability via mast cells.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 1

    Topics: Animals; Arginine; Histamine Antagonists; Intestinal Mucosa; Intestine, Small; Leukocytes; Male; Mast Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Permeability; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Superoxides

1994
Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.
    Pediatric research, 1993, Volume: 34, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hematocrit; Intestines; Male; Mesenteric Artery, Superior; Necrosis; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Superoxides

1993
The role of endogenous nitric oxide and platelet-activating factor in hypoxia-induced intestinal injury in rats.
    Gastroenterology, 1994, Volume: 106, Issue:2

    Topics: Animals; Arginine; Hypoxia; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1994
Modulation by nitric oxide of platelet-activating factor-induced albumin extravasation in the conscious rat.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Albumins; Animals; Arginine; Blood Pressure; Capillary Permeability; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar

1993
Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis.
    Gastroenterology, 1993, Volume: 105, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Azepines; Benzopyrans; Blood Pressure; Cell Adhesion; Cell Communication; Cell Movement; Leukocytes; Leukotriene B4; Mesenteric Veins; Microscopy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinacrine; Rats; Rats, Inbred WKY; Regional Blood Flow; Triazoles; Venules

1993
Nitric oxide modulates vascular permeability in the rat coronary circulation.
    British journal of pharmacology, 1993, Volume: 108, Issue:2

    Topics: Animals; Arginine; Blood Proteins; Capillary Permeability; Coronary Circulation; Endothelins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Wistar

1993
Platelet activating factor modulates microvascular permeability through nitric oxide synthesis.
    Microvascular research, 1995, Volume: 50, Issue:2

    Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Male; Mesocricetus; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Signal Transduction

1995
Nitric oxide induces vascular permeability changes in the guinea pig conjunctiva.
    European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2

    Topics: Albumins; Animals; Arginine; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Enzyme Inhibitors; Female; Guanidines; Guinea Pigs; Ketorolac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Platelet Activating Factor; Regional Blood Flow; Tolmetin; Vasodilator Agents

1995
Relationship between nitric oxide and platelet-activating factor in castor-oil induced mucosal injury in the rat duodenum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:6

    Topics: Acid Phosphatase; Animals; Castor Oil; Cathartics; Diuretics, Osmotic; Duodenum; Isosorbide; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats; Rats, Wistar

1996
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: Animals; Benzoquinones; Biphenyl Compounds; Cell Count; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Eicosanoids; Female; Heptanoic Acids; Hypotension; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Pyridinium Compounds; Tetrahydroisoquinolines; Vascular Resistance

1996
Platelet-activating factor dilates efferent arterioles through glomerulus-derived nitric oxide.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:1

    Topics: Animals; Arterioles; Enzyme Inhibitors; Humans; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Perfusion; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; Vasodilation

1996
Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis.
    European journal of pharmacology, 1996, Aug-29, Volume: 310, Issue:2-3

    Topics: Animals; Bradykinin; Carrageenan; Chemotaxis, Leukocyte; Enzyme Inhibitors; Leukocyte Count; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pleura; Rats; Rats, Wistar

1996
A balance between nitric oxide and oxidants regulates mast cell-dependent neutrophil-endothelial cell interactions.
    Circulation research, 1996, Volume: 79, Issue:5

    Topics: Animals; Cell Adhesion; Cell Communication; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Mast Cells; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidants; Oxidative Stress; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1996
Endotoxin-induced microvascular leakage is prevented by a PAF antagonist and NO synthase inhibitor.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:1

    Topics: Animals; Blood Flow Velocity; Cell Adhesion; Cricetinae; Dexamethasone; Endotoxins; Lipopolysaccharides; Male; Mesocricetus; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor

1997
Effects of platelet-activating factor on arteriolar and venular tone in rat trachea.
    Microvascular research, 1997, Volume: 53, Issue:1

    Topics: Analysis of Variance; Animals; Arterioles; Diterpenes; Enzyme Inhibitors; Ginkgolides; Lactones; Male; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Trachea; Venules

1997
Evidence for activation of cyclooxygenase-1/-2 by endogenous nitric oxide in adjuvant arthritic Lewis rats.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Animals; Arthritis, Experimental; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew

1996
Nitric oxide mediates angiogenesis induced in vivo by platelet-activating factor and tumor necrosis factor-alpha.
    The American journal of pathology, 1997, Volume: 151, Issue:2

    Topics: Animals; Azepines; Cell Movement; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Triazoles; Tumor Necrosis Factor-alpha

1997
The role of endogenous nitric oxide in the sympathetic and hemodynamic response to platelet activating factor-induced hypotension in anesthetized dogs.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:1

    Topics: Anesthetics; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Enzyme Inhibitors; Female; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Sympathetic Nervous System; Vasomotor System

1998
Mechanisms of acute vasodilator response to bacterial lipopolysaccharide in the rat coronary microcirculation.
    British journal of pharmacology, 1998, Volume: 123, Issue:4

    Topics: Animals; Annexin A1; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Cycloheximide; Dexamethasone; Enzyme Inhibitors; In Vitro Techniques; Lipopolysaccharides; Lipoxygenase; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Vasodilation

1998
The acute increases in vasomotor tone and blood pressure induced by carotid artery occlusion are modulated by platelet-activating factor (PAF) independently of nitric oxide release.
    Journal of lipid mediators and cell signalling, 1997, Volume: 17, Issue:3

    Topics: Animals; Azepines; Blood Pressure; Cardiac Output; Carotid Arteries; Carotid Stenosis; Enzyme Inhibitors; Feedback; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pressoreceptors; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles; Vascular Resistance; Vasoconstriction

1997
Microvascular permeability change induced by platelet-activating factor is impaired in diabetic mice.
    Microvascular research, 1999, Volume: 58, Issue:1

    Topics: Animals; Azo Compounds; Capillary Permeability; Coloring Agents; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Glycoconjugates; Guanidines; Hypoglycemic Agents; Indomethacin; Insulin; Male; Methylene Blue; Mice; Mice, Mutant Strains; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor; Skin; Streptozocin; Trypan Blue

1999
Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle.
    Cardiovascular research, 1999, Volume: 41, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Azepines; Cyclooxygenase Inhibitors; Depression, Chemical; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Propranolol; Triazoles; Tumor Necrosis Factor-alpha

1999
Endotoxaemia in rats: role of NO, PAF and TXA2 in pulmonary neutrophil sequestration and hyperlactataemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:3

    Topics: Animals; Azepines; Cell Movement; Endotoxemia; Indans; Lactic Acid; Lipopolysaccharides; Lung; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Triazoles

1999
Interactions of pro-inflammatory and vasoactive mediators with nitric oxide in the regulation of rat vascular permeability during laparotomy.
    European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2

    Topics: Albumins; Animals; Capillary Permeability; Enzyme Inhibitors; Inflammation; Laparotomy; Leukotrienes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxanes

2000
Role of nitric oxide in long-term potentiation of the rat medial vestibular nuclei.
    Neuroscience, 2000, Volume: 101, Issue:1

    Topics: Action Potentials; Animals; Benzoates; Electric Stimulation; Imidazoles; Long-Term Potentiation; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Platelet Activating Factor; Rats; Rats, Wistar; Signal Transduction; Synaptic Transmission; Vestibular Nuclei

2000
Role of NO and PAF in the impairment of skeletal muscle contractility induced by TNF-alpha.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Azepines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Phospholipases A; Platelet Activating Factor; S-Nitroso-N-Acetylpenicillamine; Stereoisomerism; Triazoles; Tumor Necrosis Factor-alpha

2000
Possible involvement of endothelium-derived hyperpolarizing factor (EDHF) in the depressor responses to platelet activating factor (PAF) in rats.
    British journal of pharmacology, 2000, Volume: 131, Issue:6

    Topics: Animals; Apamin; Biological Factors; Blood Pressure; Charybdotoxin; Depression, Chemical; Endothelin-1; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar

2000
The role of platelet-activating factor (PAF) antagonists and nitric oxide in cardiac actions of PAF. Electrophysiological and morphological study.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2000, Volume: 51, Issue:4 Pt 1

    Topics: 4-Aminopyridine; Action Potentials; Animals; Azepines; Diterpenes; Electrophysiology; Fibrinolytic Agents; Ginkgolides; Glyburide; Guinea Pigs; Heart; In Vitro Techniques; Lactones; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Potassium Channel Blockers; Reperfusion Injury; Triazoles

2000
Nitric oxide mediates platelet activating factor-induced microvascular leakage in rat airways.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:1

    Topics: Animals; Capillary Permeability; Coloring Agents; Enzyme Inhibitors; Evans Blue; Female; Microscopy, Fluorescence; Nasal Mucosa; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Trachea

2001
Nitric oxide/platelet activating factor cross-talk in mesangial cells modulates the interaction with leukocytes.
    Kidney international, 2002, Volume: 62, Issue:4

    Topics: Cell Adhesion; Cell Communication; Cells, Cultured; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Kidney Glomerulus; Leukocytes, Mononuclear; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor

2002
Nitric oxide attenuates platelet-activating factor induced nasal airway plasma extravasation in healthy subjects.
    European journal of clinical investigation, 2002, Volume: 32, Issue:11

    Topics: Administration, Intranasal; Adult; Albumins; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Male; Nasal Lavage Fluid; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor; Premedication; Rhinitis; Statistics, Nonparametric

2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2002
Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Adult; Arginine; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Humans; Lipopolysaccharides; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Stereoisomerism; Tumor Necrosis Factor-alpha

2003
Role of Nitric oxide in the renal and systemic vasodilatory responses to platelet-activating factor in the rat, in vivo.
    Kidney & blood pressure research, 2003, Volume: 26, Issue:3

    Topics: Acetylcholine; Animals; Arginine Vasopressin; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Injections; Injections, Intravenous; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Rats; Rats, Wistar; Renal Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2003
Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility.
    Cardiovascular research, 2003, Nov-01, Volume: 60, Issue:2

    Topics: Animals; Azepines; Class Ib Phosphatidylinositol 3-Kinase; Female; In Vitro Techniques; Isoenzymes; Mice; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Phosphatidylinositol 3-Kinases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Triazoles

2003
Candidate's thesis: Platelet-activating factor-induced hearing loss: mediated by nitric oxide?
    The Laryngoscope, 2003, Volume: 113, Issue:12

    Topics: Animals; Azepines; Cochlea; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Immunohistochemistry; Longitudinal Studies; Microscopy, Electron, Scanning; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Activating Factor; Random Allocation; Round Window, Ear; Triazoles

2003
Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Animals; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Ginkgolides; Guanylate Kinases; Intracellular Signaling Peptides and Proteins; Lactones; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Activating Factor; Precipitin Tests; Propidium; Receptors, N-Methyl-D-Aspartate

2004
Angiotensin II effect on hydraulic permeability: interaction with endothelin-1, nitric oxide, and platelet activating factor.
    The Journal of surgical research, 2006, Volume: 134, Issue:2

    Topics: Angiotensin II; Animals; Capillary Permeability; Drug Interactions; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

2006
Effects of tumor necrosis factor alpha antagonist, platelet activating factor antagonist, and nitric oxide synthase inhibitor on experimental otitis media with effusion.
    The Annals of otology, rhinology, and laryngology, 2006, Volume: 115, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Ear, Middle; Enzyme Inhibitors; Etanercept; Immunoglobulin G; Immunohistochemistry; Indoles; Injections, Intralesional; Injections, Intraperitoneal; Lipopolysaccharides; Multivariate Analysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Otitis Media with Effusion; Photomicrography; Platelet Activating Factor; Pseudomonas aeruginosa; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Thiazoles; Tumor Necrosis Factor-alpha; Tympanic Membrane

2006
Vascular permeability induced by VEGF family members in vivo: role of endogenous PAF and NO synthesis.
    Journal of cellular biochemistry, 2007, Feb-15, Volume: 100, Issue:3

    Topics: Animals; Antigens, CD; Blotting, Western; Cadherins; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphorylation; Platelet Activating Factor; Vascular Endothelial Growth Factor A

2007
L-NAME augments PAF-induced venoconstriction in isolated perfused livers of rat and guinea pig, but not mouse.
    Prostaglandins, leukotrienes, and essential fatty acids, 2007, Volume: 76, Issue:5

    Topics: Animals; Guinea Pigs; Liver; Liver Circulation; Male; Mice; NG-Nitroarginine Methyl Ester; Perfusion; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction

2007
Inhibition of human platelet aggregation by eosinophils.
    Life sciences, 2013, Sep-17, Volume: 93, Issue:9-11

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Chromatography, Gel; Collagen; Cytosol; Dextrans; Eosinophils; HL-60 Cells; Humans; Indomethacin; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Thrombin; Time Factors

2013
Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.
    The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:5

    Topics: Adherens Junctions; Anaphylaxis; Animals; Aorta; beta Catenin; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Enzyme Activation; Gene Deletion; Lung; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Signal Transduction

2013
The responses of pulmonary and systemic circulation and airway to anaphylactic mediators in anesthetized BALB/c mice.
    Life sciences, 2016, Feb-15, Volume: 147

    Topics: Anaphylaxis; Animals; Arterial Pressure; Dose-Response Relationship, Drug; Histamine; Leukotriene C4; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Prostaglandin D2; Serotonin; Vascular Resistance; Vasoconstriction; Vasodilation

2016