Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and naloxone

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with naloxone in 8 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
9,15618755220,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Esplugues, JV; Pique, JM; Whittle, BJ1
Burde, R; Schultz, G; Seifert, R1
Imura, Y; Nishikawa, K; Shino, A; Terashita, Z1
Ezra, D; Faden, AI; Feuerstein, G; Lux, WE; Snyder, F1
Bernard, GR; Weikert, LF1
Benowitz, NL; Heller, PH; Levine, JD; Miao, FJ1
Buéno, L; Fioramonti, J; Million, M; Zajac, JM1
Hou, T; Wu, K; Xiao, J; Zeng, H; Zhao, D1

Reviews

1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and naloxone

ArticleYear
Pharmacotherapy of sepsis.
    Clinics in chest medicine, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bradykinin; Cyclooxygenase Inhibitors; Humans; Naloxone; Pentoxifylline; Platelet Activating Factor; Sepsis

1996

Other Studies

7 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and naloxone

ArticleYear
Influence of morphine or capsaicin pretreatment on rat gastric microcirculatory response to PAF.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Animals; Blood Pressure; Capsaicin; Female; Gastric Mucosa; Male; Microcirculation; Morphine; Naloxone; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow

1990
Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:1

    Topics: Adenosine Triphosphate; Alprostadil; Biotransformation; Endorphins; Enkephalin, Methionine; Humans; In Vitro Techniques; Leukemia, Experimental; Morphine; N-Formylmethionine Leucyl-Phenylalanine; Naloxone; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Superoxides; Tumor Cells, Cultured

1989
A lethal role of platelet activating factor in anaphylactic shock in mice.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Dexamethasone; Male; Mice; Mice, Inbred Strains; Naloxone; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; SRS-A; Thiazoles

1987
Hypotension produced by platelet-activating factor is reversed by thyrotropin-releasing hormone.
    Circulatory shock, 1984, Volume: 13, Issue:3

    Topics: Animals; Blood Pressure; Guinea Pigs; Hypotension; Male; Naloxone; Platelet Activating Factor; Thiazolidines; Thyrotropin-Releasing Hormone; Time Factors

1984
Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat.
    British journal of pharmacology, 1997, Volume: 120, Issue:2

    Topics: Adrenal Glands; Animals; Bradykinin; Capillary Permeability; Male; Mecamylamine; Mifepristone; Naloxone; Nicotine; Platelet Activating Factor; Propanolamines; Rats; Rats, Sprague-Dawley

1997
Effects of neuropeptide FF on intestinal motility and temperature changes induced by endotoxin and platelet-activating factor.
    European journal of pharmacology, 1997, Sep-03, Volume: 334, Issue:1

    Topics: Animals; Body Temperature; Endotoxins; Gastrointestinal Motility; Male; Myoelectric Complex, Migrating; Naloxone; Narcotic Antagonists; Oligopeptides; Platelet Activating Factor; Rats; Rats, Wistar

1997
Synergetic protective effects of combined blockade by two kinds of autolesion mediator receptor on neurological function after cervical cord injury.
    Chinese medical journal, 1998, Volume: 111, Issue:5

    Topics: Animals; Cats; Diterpenes; Drug Synergism; Ginkgolides; Lactones; Male; Naloxone; Narcotic Antagonists; Platelet Activating Factor; Platelet Membrane Glycoproteins; Random Allocation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Spinal Cord; Spinal Cord Injuries

1998