1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with modipafant in 19 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (modipafant) | Trials (modipafant) | Recent Studies (post-2010) (modipafant) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 29 | 3 | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (68.42) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, K; Fray, MJ; Parry, MJ; Richardson, K; Steele, J | 1 |
| Alabaster, VA; de Souza, RN; Keir, RF; Parry, MJ | 1 |
| Das, A; Larkin, SW; Nourshargh, S; Williams, TJ | 1 |
| Angus, RM; Barnes, NC; Barnes, PJ; Bone, MF; Chung, KF; Fairfax, AJ; Higenbotham, TW; Kuitert, LM; O'Connor, BJ; Piotrowska, B | 1 |
| Alabaster, VA; Cheeseman, HE; Cooper, K; deSouza, RN; Keir, RF; Parry, MJ | 1 |
| Bolanowski, MA; Nourshargh, S; Sanz, MJ; Weg, VB | 1 |
| Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Barnes, PJ; Carty, TJ; Chung, KF; Eskra, JD; O'Connor, BJ; Uden, S | 1 |
| Barnes, NC; Burke, W; Hui, KP; Kuitert, LM; Newland, AC; Uden, S; Uthayarkumar, S | 1 |
| Norman, KE; Nourshargh, S; Pons, F; Rossi, AG; Williams, TJ | 1 |
| Chilvers, ER; Condliffe, AM; Haslett, C; Kitchen, E; Rossi, AG | 1 |
| Norman, KE; Rossi, AG; Williams, TJ | 1 |
| Hellewell, PG; Jeffery, PK; Miotla, JM | 1 |
| Benjamim, CF; Cunha, Fde Q; Ferreira, SH; Rios-Santos, F; Zavery, D | 1 |
| Ishii, S; Pinho, V; Shimizu, T; Soares, AC; Souza, DG; Teixeira, MM | 1 |
| Andrade, SP; Barcelos, LS; Campos, PP; Ferreira, MA; Teixeira, MM; Vasconcelos, AC | 1 |
| Bélanger, C; Borgeat, P; Elimam, H; Lefebvre, J; Marleau, S | 1 |
| Borgeat, P; Flamand, N; Lefebvre, JS; Lévesque, T; Marleau, S; Milot, V; Picard, S | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and modipafant
| Article | Year |
|---|---|
Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma.
Topics: Adult; Aged; Asthma; Dihydropyridines; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Imidazoles; Male; Middle Aged; Peak Expiratory Flow Rate; Platelet Activating Factor; Quality of Life; Single-Blind Method | 1995 |
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Bronchoconstriction; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Eicosanoids; Humans; Imidazoles; Leukocyte Count; Leukotriene E4; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1994 |
Effect of the platelet-activating factor antagonist UK-74,505 on the early and late response to allergen.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Dihydropyridines; Double-Blind Method; Forced Expiratory Volume; Humans; Imidazoles; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation | 1993 |
16 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and modipafant
| Article | Year |
|---|---|
1,4-Dihydropyridines as antagonists of platelet activating factor. 1. Synthesis and structure-activity relationships of 2-(4-heterocyclyl)phenyl derivatives.
Topics: Animals; Dihydropyridines; Dogs; Imidazoles; Mice; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship | 1992 |
UK-74,505, a novel and selective PAF antagonist, exhibits potent and long lasting activity in vivo.
Topics: Animals; Blood Cells; Bronchoconstriction; Capillary Permeability; Cell Aggregation; Dihydropyridines; Dogs; Female; Guinea Pigs; Imidazoles; Male; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles | 1995 |
Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity.
Topics: Administration, Oral; Animals; Aorta; Azepines; Blood Platelets; Brain; Calcium Channels, L-Type; Capillary Permeability; Cattle; Dihydropyridines; Diltiazem; Gallopamil; Guinea Pigs; Hypotension; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Proteins; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Rabbits; Rats; Rats, Sprague-Dawley; Skin; Triazoles; Tritium | 1994 |
IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody.
Topics: Animals; Antibodies, Monoclonal; Calcium; Chemotaxis, Leukocyte; Dactinomycin; Dihydropyridines; Edema; Eosinophils; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Skin | 1995 |
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan | 1994 |
Role of platelet-activating factor (PAF) in platelet accumulation in rabbit skin: effect of the novel long-acting PAF antagonist, UK-74,505.
Topics: Animals; Arthus Reaction; Blood Platelets; Calcium; Dihydropyridines; Edema; Fura-2; Imidazoles; In Vitro Techniques; Indium Radioisotopes; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin; Skin; Zymosan | 1993 |
Demonstration of reversible priming of human neutrophils using platelet-activating factor.
Topics: Adult; Azepines; Cell Adhesion; Cell Polarity; Cell Size; Cells, Cultured; Dihydropyridines; Enzyme Activation; Humans; Imidazoles; Macrophage-1 Antigen; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Superoxides; Time Factors; Triazoles; Tumor Necrosis Factor-alpha | 1996 |
Comparison of the reversed passive Arthus and local Shwartzman reactions of rabbit skin: effects of the long-acting PAF antagonist UK-74,505.
Topics: Animals; Arthus Reaction; Cell Aggregation; Dihydropyridines; Imidazoles; Neutrophils; Platelet Activating Factor; Rabbits; Shwartzman Phenomenon | 1997 |
Platelet-activating factor plays a pivotal role in the induction of experimental lung injury.
Topics: Animals; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Elapid Venoms; Extravascular Lung Water; Female; Humans; Imidazoles; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Serum Albumin; Skin; Zymosan | 1998 |
A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligaton and puncture sepsis.
Topics: Animals; Cecum; Cell Movement; Dihydropyridines; Eicosanoids; Imidazoles; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peritoneum; Platelet Activating Factor; Prostaglandins; Time Factors; Wounds, Penetrating | 2003 |
Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Imidazoles; Intestinal Diseases; Intestines; Lung Diseases; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reperfusion Injury | 2003 |
Sponge-induced angiogenesis and inflammation in PAF receptor-deficient mice (PAFR-KO).
Topics: Acetylglucosaminidase; Administration, Topical; Animals; Blood Vessels; Chemokines; Dihydropyridines; Fibroblasts; Granulation Tissue; Granuloma; Hemoglobins; Imidazoles; Implants, Experimental; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Knockout; Neovascularization, Pathologic; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polyurethanes; Porifera; Receptors, G-Protein-Coupled; Skin | 2004 |
Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats.
Topics: Animals; Benzopyrans; Carboxylic Acids; Dermatitis; Dihydropyridines; Imidazoles; Leukotriene B4; Male; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Skin; Thiazoles | 2008 |
Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor.
Topics: Animals; Azepines; Cell Movement; Dihydropyridines; Female; Flagellin; Humans; Imidazoles; Leukotriene B4; Ligands; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Poly I-C; Propionates; Quinolines; Thienopyridines; Toll-Like Receptors; Triazoles | 2010 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |