Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and mifepristone

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with mifepristone in 5 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(mifepristone)
Trials
(mifepristone)
Recent Studies (post-2010) (mifepristone)
9,1561875526,5365951,758

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)mifepristone (IC50)
Glucocorticoid receptor Canis lupus familiaris (dog)0.0264
Bile salt export pumpHomo sapiens (human)2.02
Estrogen receptorHomo sapiens (human)4.311
Glucocorticoid receptorHomo sapiens (human)0.0249
Prostaglandin G/H synthase 1Ovis aries (sheep)0.0003
Progesterone receptorHomo sapiens (human)0.1347
Glucocorticoid receptorRattus norvegicus (Norway rat)0.774
Glucocorticoid receptorMus musculus (house mouse)0.0022
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0022
Mineralocorticoid receptor Homo sapiens (human)2.0938
Cytochrome P450 3A4Homo sapiens (human)9.5
Coagulation factor VIIHomo sapiens (human)0.0003
Androgen receptorHomo sapiens (human)0.2988
Cytochrome P450 2C8Homo sapiens (human)1.5
Cytochrome P450 2C9 Homo sapiens (human)4.9
Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Norway rat)0.0016
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.555
Tissue factorHomo sapiens (human)0.0003
Androgen receptorRattus norvegicus (Norway rat)0.0083
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0014
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.0022
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0022
Prostaglandin G/H synthase 1Homo sapiens (human)0.0078
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0022
Substance-P receptorCavia porcellus (domestic guinea pig)0.0015
Mu-type opioid receptorHomo sapiens (human)2.457
Estrogen receptor betaHomo sapiens (human)1.528
Glucocorticoid receptorSus scrofa (pig)0.0153

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Flower, RJ; Harris, JG; Perretti, M1
Hughes, SC; Whelan, CJ; Wren, GP1
Benowitz, NL; Heller, PH; Levine, JD; Miao, FJ1
Gardner, JP; Zhang, L1
Gao, L; He, M; Ni, X; Sun, Y; Tang, G; Wang, L; Xu, B; Yu, Y1

Other Studies

5 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and mifepristone

ArticleYear
Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Annexin A1; Kinetics; Leukocytes; Male; Mice; Mice, Inbred Strains; Mifepristone; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Time Factors

1995
Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:3

    Topics: Acute Disease; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Histamine; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mifepristone; Neutrophils; Platelet Activating Factor; Pneumonia; Skin

1995
Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat.
    British journal of pharmacology, 1997, Volume: 120, Issue:2

    Topics: Adrenal Glands; Animals; Bradykinin; Capillary Permeability; Male; Mecamylamine; Mifepristone; Naloxone; Nicotine; Platelet Activating Factor; Propanolamines; Rats; Rats, Sprague-Dawley

1997
Glucocorticoid modulation of Ca2+ homeostasis in human B lymphoblasts.
    The Journal of physiology, 1999, Jan-15, Volume: 514 ( Pt 2)

    Topics: B-Lymphocytes; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Fura-2; Glucocorticoids; Homeostasis; Humans; Hydrocortisone; Kinetics; Manganese; Mifepristone; Platelet Activating Factor; Regression Analysis; Signal Transduction; Thapsigargin

1999
Effects of platelet-activating factor and its differential regulation by androgens and steroid hormones in prostate cancers.
    British journal of cancer, 2013, Sep-03, Volume: 109, Issue:5

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Androgen Receptor Antagonists; Androgens; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclofenil; Dihydrotestosterone; Disease Progression; Estradiol; Hormone Antagonists; Humans; Imidazoles; Indoles; Male; Mifepristone; Platelet Activating Factor; Prostatic Neoplasms; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Wnt Proteins

2013