1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with methysergide in 24 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (methysergide) | Trials (methysergide) | Recent Studies (post-2010) (methysergide) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 2,935 | 81 | 80 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | methysergide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0021 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.631 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.807 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 4.763 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.054 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.943 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0021 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.054 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.172 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.162 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (58.33) | 18.7374 |
| 1990's | 10 (41.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB | 1 |
| Cordeiro, RS; Watson, ML; Weg, VB; Williams, TJ | 1 |
| Braquet, P; Carrier, J; Jancar, S; Sirois, MG; Sirois, P | 1 |
| Krell, RD; McCarthy, M | 1 |
| Braquet, P; Carré, C; Lavaud, P; Mencia-Huerta, JM; Rodrigue, F; Touvay, C | 1 |
| Ikeda, K; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Driscoll, EM; Jackson, CV; Kunkel, SL; Lucchesi, BR; Schumacher, WA | 1 |
| Leff, AR; Munoz, NM; Popovich, KJ; Shioya, T; Stimler-Gerard, NP; White, SR | 1 |
| Fischer, JJ; Rohrbach, MS; Rolstad, RA; Russell, JA | 1 |
| Blake, J; Denberg, P; Leff, AR; Mack, M; Munoz, NM; Popovich, KJ; Sheldon, G; White, SR | 1 |
| Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K | 1 |
| Braquet, P; Etienne, A; Hecquet, F | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Baer, PG; Cagen, LM | 1 |
| Bergstrand, H; Dahlbäck, M; Sörenby, L | 1 |
| Benveniste, J; Bonnet, J; Page, CP; Paul, W; Pfister, A; Pirotzky, E; Roubin, R | 1 |
| Barton, M; Lefort, J; Prancan, A; Vargaftig, BB | 1 |
| Chignard, M; Lefort, J; Medeiros, MC; Vargaftig, BB; Wal, F | 1 |
| Langer, JC; Liebman, SM; Monk, PK; Pelletier, GJ | 1 |
| Barnes, PJ; Chung, KF; Elwood, W; Sakamoto, T | 1 |
| Boichot, E; Braquet, P; Kyriacopoulos, F; Lagente, V; Mencia-Huerta, JM | 1 |
| de Abreu Castro, MS; Dias, MF; Farinelli, P; Ferreira-Alves, DL; Francischi, JN; Kiyomi Funayama Tatsuo, MA; Pacheco, CM; Rocha, OA; Sirois, P | 1 |
| Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A | 1 |
24 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and methysergide
| Article | Year |
|---|---|
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles | 1991 |
Histamine, leukotriene D4 and platelet-activating factor in guinea pig passive cutaneous anaphylaxis.
Topics: Acetophenones; Animals; Autacoids; Azepines; Blood Proteins; Bradykinin; Capillary Permeability; Chlorpheniramine; Cimetidine; Guinea Pigs; Histamine; Male; Methysergide; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; SRS-A; Tetrazoles; Triazoles | 1991 |
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; Indomethacin; Lactones; Male; Methysergide; Peritoneal Cavity; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
Pharmacologic modulation of picryl chloride-induced contact dermatitis in the mouse.
Topics: Animals; Betamethasone; Dermatitis, Contact; Dose-Response Relationship, Drug; Indomethacin; Lactones; Male; Methysergide; Mice; Mice, Inbred BALB C; Picryl Chloride; Plant Extracts; Platelet Activating Factor | 1991 |
Platelet-activating factor increases platelet-dependent glycoconjugate secretion from tracheal submucosal gland.
Topics: Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cats; Fatty Acids, Unsaturated; Glucosamine; Glycoconjugates; Hydrazines; In Vitro Techniques; Indomethacin; Kinetics; Methysergide; Mucous Membrane; Phospholipid Ethers; Platelet Activating Factor; Radioisotope Dilution Technique; Thromboxane A2; Trachea; Tritium | 1989 |
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
Topics: Animals; Aspirin; Coronary Circulation; Coronary Vessels; Diphenhydramine; Dogs; Histamine H1 Antagonists; Male; Methacholine Compounds; Methysergide; Nitroglycerin; Platelet Activating Factor; Thrombocytopenia; Vasodilation | 1986 |
Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.
Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Platelet Activating Factor; Reference Values; Trachea | 1987 |
Changes in the levels of bioactive components of cotton bracts accompanying senescence.
Topics: Animals; Atropine; Blood Platelets; Dogs; Endotoxins; Gossypium; Humans; In Vitro Techniques; Methysergide; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Serotonin; Spectrophotometry; Tannins; Time Factors | 1988 |
Role of platelets in contraction of canine tracheal muscle elicited by PAF in vitro.
Topics: Animals; Atropine; Blood Platelets; Dogs; Female; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Serotonin; Tachyphylaxis; Trachea | 1988 |
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis | 1988 |
Possible involvement of platelet-activating factor in endotoxin-induced abortion.
Topics: Abortion, Spontaneous; Animals; Diterpenes; Endotoxins; Female; Ginkgolides; Gonadotropins, Equine; Lactones; Methysergide; Mice; Platelet Activating Factor; Pre-Eclampsia; Pregnancy | 1988 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Platelet activating factor vasoconstriction of dog kidney. Inhibition by alprazolam.
Topics: Alprazolam; Animals; Blood Pressure; Dogs; Ergolines; Female; Kidney; Male; Meclofenamic Acid; Methysergide; Platelet Activating Factor; Platelet Aggregation; Regional Blood Flow; Saralasin; Vascular Resistance; Vasoconstriction | 1987 |
Bronchial anaphylaxis in actively sensitized Sprague Dawley rats: studies on mediators involved.
Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bronchi; Cyclooxygenase Inhibitors; Immunization; Indomethacin; Male; Methysergide; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; Vagotomy | 1984 |
PAF-acether-induced plasma exudation in rat skin is independent of platelets and neutrophils.
Topics: Animals; Blood Platelets; Blood Proteins; Capillary Permeability; Indomethacin; Male; Methysergide; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains; Skin | 1984 |
Relaxation of the guinea-pig trachea induced by platelet-activating factor and by serotonin.
Topics: Acetylcholine; Animals; Aspirin; Blood Platelets; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lysophosphatidylcholines; Male; Methysergide; Muscle Relaxation; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Serotonin; Trachea | 1982 |
Non-steroidal anti-inflammatory drugs if combined with anti-histamine and anti-serotonin agents interfere with the bronchial and platelet effects of "platelet-activating factor" (PAF-acether).
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Blood Platelets; Bronchi; Drug Interactions; Histamine Antagonists; Humans; In Vitro Techniques; Methysergide; Muscle Contraction; Platelet Activating Factor; Pyrilamine; Serotonin Antagonists | 1982 |
Mast cell mediators and peritoneal adhesion formation in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Histamine Antagonists; Leukotriene D4; Male; Mast Cells; Methysergide; Ondansetron; Peritoneal Diseases; Platelet Activating Factor; Propionates; Pyrilamine; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Adhesions; Triazoles | 1995 |
Role of cyclooxygenase and 5-lipoxygenase metabolites, platelet-activating factor and 5-hydroxytryptamine in allergen-induced airway responses in the brown Norway rat.
Topics: Allergens; Animals; Arachidonate 5-Lipoxygenase; Asthma; Azepines; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Hypersensitivity, Immediate; Male; Methysergide; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred BN; Serotonin; Triazoles | 1994 |
Role of PAF in the late airway microvascular leakage induced by antigen in IgE-sensitized rat.
Topics: Administration, Oral; Animals; Antigens; Azepines; Bronchi; Capillary Permeability; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Immunoglobulin E; Injections, Intravenous; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Specific Pathogen-Free Organisms; Thienopyridines; Trachea; Triazoles | 1995 |
Pharmacological characterization of Sephadex-induced oedema in rat paws: predominant role of serotonin and platelet-activating factor.
Topics: Animals; Bradykinin; Cyclosporine; Dexamethasone; Dextrans; Diterpenes; Edema; Ginkgolides; Histamine; Immunosuppressive Agents; Inflammation Mediators; Injections, Intravenous; Lactones; Male; Methysergide; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Polyenes; Rats; Serotonin; Serotonin Antagonists; Sirolimus | 1996 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |