Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and methacholine chloride

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with methacholine chloride in 45 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(methacholine chloride)
Trials
(methacholine chloride)
Recent Studies (post-2010) (methacholine chloride)
9,1561875525,443835824

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)methacholine chloride (IC50)
galanin receptor type 3Homo sapiens (human)7.365

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19909 (20.00)18.7374
1990's32 (71.11)18.2507
2000's4 (8.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Q1
Bellofiore, S; Ciancio, N; Di Maria, GU; Mistretta, A; Ruggieri, F1
Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Tuomisto, L; Vapaatalo, H1
Bethel, RA; Tan, WC1
Britten, KM; Djukanović, R; Holgate, ST; Howarth, PH; Lai, CK; Wilson, JW; Wilson, SJ1
Fiz, JA; Monreal, M; Monsó, E; Morera, J; Roncalés, J; Ruiz, J; Sala, H1
Morikawa, T; Webber, SE; Widdicombe, JG1
Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Vapaatalo, H1
Drazen, JM; Martins, MA; Shore, SA1
Agrawal, DK; Bergren, DR; Byorth, PJ; Townley, RG1
Gundel, RH; Letts, LG; Wegner, CD1
Chan, H; Chan-Yeung, M; Lam, S; Salari, H; Tse, KS1
Hsieh, KH1
Adachi, M; Hiyama, T; Idaira, K; Imai, T; Maeda, M; Saito, C; Suganuma, T; Takahashi, T; Tsuji, A1
Kaye, MG; Smith, LJ1
Holgate, ST; Jenkins, JR; Lai, CK; Polosa, R1
Agrawal, DK; Bewtra, AK; Hopp, RJ; Nabe, M; Townley, RG1
Barnes, PJ; Chung, KF; Collins, JV; Hartnell, A; Kay, AB; MacDonald, AJ; McCusker, M; Moqbel, R; Wardlaw, AJ1
Drazen, JM; Galli, SJ; Gerard, NP; Martin, TR1
Barnes, PJ; Chung, KF; Dent, G1
Barnes, PJ; Chung, KF1
Agrawal, DK; Bewtra, AK; Hopp, RJ; Townley, RG1
Barnes, PJ; Chung, KF; Lammers, JW; McCusker, M; Nichol, GM; Roberts, NM1
Agrawal, DK; Townley, RG1
Barnes, PJ; Chung, KF; McCusker, M; Minette, P1
Patterson, R; Rubin, AH; Smith, LJ1
Adachi, M; Imai, T; Kamiya, I; Kobayashi, H; Nishikata, H; Okazawa, A; Satoh, H; Takahashi, T; Yamaguchi, H1
Haruta, Y; Hozawa, S; Ishioka, S; Yamakido, M1
Bury, T; Corhay, JL; Degroote, D; Franchimont, P; Kayembe, JM; Louis, R; Radermecker, MF1
Ho, CY; Tsai, JJ; Wang, SR1
Bury, T; Corhay, JL; Louis, R; Radermecker, MF1
Bellofiore, S; Ciancio, N; Coco, G; Di Maria, GU; Novo, S; Passanisi, G; Pennisi, A; Ricciardolo, FL1
Campos, MG; Church, MK; Joseph, D; Lefort, J; Pretolani, M; Ruffié, C; Vargaftig, BB1
Houston, M; Shamsuddin, M; Smith, LJ1
Louis, RE; Radermecker, MF1
Jouët, P; Sarna, SK1
Ikuta, K; Ishii, S; Kume, K; Miyazaki, J; Nagase, T; Sato, S; Shimizu, T; Tashiro, F; Waga, I1
Chen, IS; Ishii, H; Ishikawa, T; Ko, FN; Kuo, HP; Lin, CH; Teng, CM1
Ikuta, K; Ishii, S; Komagata, Y; Kume, K; Maki, K; Miyazaki, J; Nagase, T; Nakatani, N; Ouchi, Y; Shimizu, T; Tashiro, F; Uozumi, N1
Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG1
Held, HD; Martin, C; Uhlig, S1
Chi, EY; Dietsch, GN; Henderson, WR; Lu, J; Poole, KM1
Ishii, S; Nagase, T; Ouchi, Y; Shimizu, T; Shindou, H1
Amemiya, T; Fujimura, M; Ishiura, Y; Kurashima, K; Myou, S; Nobata, K; Nonomura, A1
Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ1

Trials

11 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and methacholine chloride

ArticleYear
[Effects of inhaled aerosol of platelet activating factor on pulmonary function and airway responsiveness in normal subjects].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1992, Volume: 15, Issue:4

    Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Chlorpheniramine; Double-Blind Method; Humans; Lung; Male; Methacholine Chloride; Platelet Activating Factor; Respiratory Function Tests

1992
Nedocromil sodium inhibits the increase in airway reactivity induced by platelet activating factor in humans.
    Chest, 1992, Volume: 102, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Double-Blind Method; Forced Expiratory Volume; Humans; Male; Maximal Expiratory Flow-Volume Curves; Methacholine Chloride; Nedocromil; Platelet Activating Factor; Quinolones; Vital Capacity

1992
Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:6

    Topics: Administration, Inhalation; Adult; Blood Platelets; Bronchodilator Agents; Budesonide; Catecholamines; Drug Synergism; Female; Histamine; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Platelet Count; Pregnenediones; Reference Values; Thromboxane B2

1992
Effect of inhaled platelet-activating factor on bronchial inflammation in atopic non-asthmatic subjects.
    International archives of allergy and immunology, 1992, Volume: 99, Issue:1

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Cell Degranulation; Double-Blind Method; Eosinophils; Female; Humans; Male; Mast Cells; Methacholine Chloride; Placebos; Platelet Activating Factor

1992
Effects of PAF antagonist, BN52021, on the PAF-, methacholine-, and allergen-induced bronchoconstriction in asthmatic children.
    Chest, 1991, Volume: 99, Issue:4

    Topics: Allergens; Asthma; Blood Cell Count; Bronchial Provocation Tests; Bronchoconstriction; Child; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Lactones; Male; Methacholine Chloride; Plant Extracts; Platelet Activating Factor

1991
Effects of salbutamol on bronchoconstriction, bronchial hyperresponsiveness, and leucocyte responses induced by platelet activating factor in man.
    Thorax, 1989, Volume: 44, Issue:2

    Topics: Adult; Airway Resistance; Albuterol; Blood Cell Count; Bronchi; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Leukocytosis; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor

1989
Effect of theophylline on airway responses to inhaled platelet-activating factor in man.
    The European respiratory journal, 1989, Volume: 2, Issue:8

    Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Randomized Controlled Trials as Topic; Theophylline

1989
Ketotifen inhibits the cutaneous but not the airway responses to platelet-activating factor in man.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:6

    Topics: Adult; Aerosols; Blood Cell Count; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Humans; Ketotifen; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Random Allocation; Skin Tests

1988
Effects of a PAF antagonist, Y-24180, on bronchial hyperresponsiveness in patients with asthma.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:4 Pt 1

    Topics: Adult; Analysis of Variance; Asthma; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles

1995
Changes in bronchial responsiveness, circulating leucocytes and ex vivo cytokine production by blood monocytes after PAF inhalation in allergic asthmatics.
    The European respiratory journal, 1995, Volume: 8, Issue:4

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Enzyme-Linked Immunosorbent Assay; Female; Humans; Interleukin-1; Leukocyte Count; Leukocytes, Mononuclear; Male; Methacholine Chloride; Platelet Activating Factor; Single-Blind Method; Tumor Necrosis Factor-alpha

1995
Effect of leukotriene D4 and platelet-activating factor on human alveolar macrophage eicosanoid and PAF synthesis.
    The American review of respiratory disease, 1993, Volume: 148, Issue:3

    Topics: Adult; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chromatography, High Pressure Liquid; Eicosanoids; Humans; Macrophages, Alveolar; Male; Methacholine Chloride; Platelet Activating Factor; Reference Values; Respiratory Function Tests; SRS-A

1993

Other Studies

34 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and methacholine chloride

ArticleYear
The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs.
    The American review of respiratory disease, 1992, Volume: 146, Issue:4

    Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Eosinophils; Furans; Guinea Pigs; Male; Methacholine Chloride; Ozone; Platelet Activating Factor; Respiratory Function Tests

1992
Effects of inhaled platelet activating factor on bronchial responsiveness in patients with symptomatic and asymptomatic pulmonary embolism.
    Chest, 1992, Volume: 102, Issue:3

    Topics: Administration, Inhalation; Bronchial Provocation Tests; Bronchoconstriction; Female; Humans; Lung; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Pulmonary Embolism; Radionuclide Imaging

1992
PAF-induced muscarinic cholinoceptor hyperresponsiveness of ferret tracheal smooth muscle and gland secretion in vitro.
    British journal of pharmacology, 1992, Volume: 105, Issue:1

    Topics: Albumins; Animals; Biological Transport; Exocrine Glands; Ferrets; In Vitro Techniques; Methacholine Chloride; Mucus; Muramidase; Muscle, Smooth; Platelet Activating Factor; Receptors, Muscarinic; Trachea

1992
Platelet-activating factor impairs mucociliary transport and increases plasma leukotriene B4 in man.
    The European respiratory journal, 1991, Volume: 4, Issue:5

    Topics: Administration, Inhalation; Adult; Aspirin; Bronchi; Female; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Mucociliary Clearance; Platelet Activating Factor; Platelet Aggregation; Respiratory Mechanics

1991
Release of tachykinins by histamine, methacholine, PAF, LTD4, and substance P from guinea pig lungs.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Kinetics; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Platelet Activating Factor; SRS-A; Substance P; Tachykinins

1991
Platelet-activating factor induces nonspecific desensitization to bronchodilators in guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Airway Resistance; Animals; Desensitization, Immunologic; Dihydroalprenolol; Dinoprostone; Drug Interactions; Guinea Pigs; Isoproterenol; Lung; Male; Methacholine Chloride; Platelet Activating Factor; Tritium

1991
The role of platelet activating factor in airway inflammation, airway hyperresponsiveness, and pulmonary function in monkeys.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Aerosols; Animals; Antigens; Azepines; Bronchoconstriction; Lung; Macaca fascicularis; Male; Methacholine Chloride; Neutrophils; Platelet Activating Factor; Respiratory Physiological Phenomena; Respiratory System; Triazoles

1991
The release of platelet-activating factor into plasma during allergen-induced bronchoconstriction.
    The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:3

    Topics: Biological Assay; Bronchial Provocation Tests; Bronchoconstriction; Chromatography, High Pressure Liquid; Humans; Methacholine Chloride; Platelet Activating Factor; Pollen; Respiratory Hypersensitivity

1991
[The role of thromboxane A2 in the development of airway responsiveness after platelet activating factor inhalation in dogs].
    Arerugi = [Allergy], 1991, Volume: 40, Issue:1

    Topics: Administration, Inhalation; Airway Resistance; Animals; Benzoquinones; Bronchi; Bronchoalveolar Lavage Fluid; Dogs; Female; Heptanoic Acids; Leukocyte Count; Methacholine Chloride; Platelet Activating Factor; Quinones; Thromboxane A2

1991
Effects of inhaled leukotriene D4 and platelet-activating factor on airway reactivity in normal subjects.
    The American review of respiratory disease, 1990, Volume: 141, Issue:4 Pt 1

    Topics: Administration, Inhalation; Adult; Airway Resistance; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Histamine; Humans; Longitudinal Studies; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Reference Values; Single-Blind Method; SRS-A

1990
Inhaled PAF fails to induce airway hyperresponsiveness to methacholine in normal human subjects.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:3

    Topics: Administration, Inhalation; Adult; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Male; Maximal Expiratory Flow Rate; Methacholine Chloride; Methacholine Compounds; Middle Aged; Platelet Activating Factor; Tachycardia; Vital Capacity

1990
Effect of PAF-acether inhalation on nonspecific bronchial reactivity and adrenergic response in normal and asthmatic subjects.
    Chest, 1990, Volume: 98, Issue:4

    Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Isoproterenol; Leukocyte Count; Male; Methacholine Chloride; Platelet Activating Factor

1990
Effects of inhaled PAF in humans on circulating and bronchoalveolar lavage fluid neutrophils. Relationship to bronchoconstriction and changes in airway responsiveness.
    The American review of respiratory disease, 1990, Volume: 141, Issue:2

    Topics: Administration, Inhalation; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Humans; Leukocyte Count; Methacholine Chloride; Methacholine Compounds; Neutrophils; Platelet Activating Factor

1990
Pulmonary responses to bronchoconstrictor agonists in the mouse.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6

    Topics: Animals; Histamine; Indomethacin; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Mice; Mice, Inbred C57BL; Norepinephrine; Platelet Activating Factor; Plethysmography; Propranolol; Prostaglandins; Reference Values; Serotonin; SRS-A; Substance P

1988
Effects of platelet activating factor on airway calibre, airway responsiveness, and circulating cells in asthmatic subjects.
    Thorax, 1989, Volume: 44, Issue:2

    Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Humans; Isoproterenol; Leukocyte Count; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor

1989
Effect of platelet-activating factor inhalation on nonspecific bronchial reactivity in man.
    Chest, 1989, Volume: 96, Issue:5

    Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Platelet Activating Factor; Time Factors

1989
Effect of platelet-activating factor on beta-adrenoceptors in human lung.
    Biochemical and biophysical research communications, 1987, Feb-27, Volume: 143, Issue:1

    Topics: Cell Membrane; Dihydroalprenolol; Histamine; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Receptors, Adrenergic, beta; Trachea

1987
The bronchoconstrictor properties of platelet-activating factor in humans.
    The American review of respiratory disease, 1987, Volume: 136, Issue:5

    Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Tachyphylaxis

1987
[The effect of a specific antagonist of PAF (CV-3988) on airway hyperresponsiveness induced by ozone exposure in beagles].
    Arerugi = [Allergy], 1987, Volume: 36, Issue:6

    Topics: Animals; Bronchi; Dogs; Female; Methacholine Chloride; Methacholine Compounds; Ozone; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane B2

1987
Relationship between nasal resistance and airway hyperreactivity following nasal provocation with Dermatophagoides pteronyssinus in allergic rhinitis.
    International archives of allergy and immunology, 1995, Volume: 106, Issue:3

    Topics: Adolescent; Adult; Allergens; Antigens, Dermatophagoides; Bronchial Hyperreactivity; Eosinophils; Female; Glycoproteins; Humans; Leukocyte Count; Leukotriene B4; Leukotriene C4; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Platelet Activating Factor; Rhinitis, Allergic, Perennial

1995
Acute bronchial and hematologic effects following inhalation of a single dose of PAF. Comparison between asthmatics and normal subjects.
    Chest, 1994, Volume: 106, Issue:4

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Male; Methacholine Chloride; Monocytes; Neutrophils; Platelet Activating Factor; Time Factors

1994
Inhaled platelet-activating factor increases airway sensitivity but not maximal airway narrowing to methacholine in normal subjects.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1994, Volume: 49, Issue:4

    Topics: Administration, Inhalation; Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Male; Maximal Expiratory Flow Rate; Maximal Expiratory Flow-Volume Curves; Methacholine Chloride; Peak Expiratory Flow Rate; Platelet Activating Factor; Pulmonary Ventilation; Total Lung Capacity; Vital Capacity

1994
Role of eosinophil activation in the bronchial reactivity of allergic guinea pigs.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:5

    Topics: Animals; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Leukotriene B4; Male; Methacholine Chloride; Ovalbumin; Peroxidases; Platelet Activating Factor; Proteins; Respiratory Hypersensitivity; Ribonucleases

1994
Acute bronchial obstruction following inhalation of PAF in asthmatic and normal subjects: comparison with methacholine.
    The European respiratory journal, 1996, Volume: 9, Issue:7

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Case-Control Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Platelet Activating Factor; Tachyphylaxis

1996
Platelet-activating factor (PAF) stimulates giant migrating contractions during ileal inflammation.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1

    Topics: Animals; Calcium; Dogs; Female; Ileitis; Ileum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Neostigmine; Platelet Activating Factor; Substance P

1996
Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor.
    The EMBO journal, 1997, Jan-02, Volume: 16, Issue:1

    Topics: Animals; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Endotoxins; Female; Fertility; Guinea Pigs; Male; Melanoma, Experimental; Methacholine Chloride; Mice; Mice, Transgenic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sex Ratio; Shock, Septic; Skin Neoplasms

1997
The effect of the selective PAF antagonist CIS-19 on PAF- and antigen-induced bronchoconstriction, microvascular leakage and bronchial hyperreactivity in guinea-pigs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Airway Resistance; Animals; Antigens; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Guinea Pigs; Histamine; Male; Methacholine Chloride; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Hypersensitivity; Substance P; Tetrahydronaphthalenes

1997
Role of cytosolic phospholipase A2 in allergic response and parturition.
    Nature, 1997, Dec-11, Volume: 390, Issue:6660

    Topics: Anaphylaxis; Animals; Bronchial Hyperreactivity; Chimera; Cloning, Molecular; Cytosol; Eicosanoids; Female; Gene Targeting; Hypersensitivity; Labor, Obstetric; Macrophages, Peritoneal; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pregnancy

1997
Effects of S-salbutamol on human isolated bronchus.
    Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:1

    Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor

1998
Characterization of airway and vascular responses in murine lungs.
    British journal of pharmacology, 1999, Volume: 126, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Bombesin; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Endothelin-1; Female; Histidine; In Vitro Techniques; Leukotriene C4; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Perfusion; Platelet Activating Factor; Serotonin; Substance P; Vasoconstriction; Vasoconstrictor Agents

1999
Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Mar-15, Volume: 164, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Movement; Disease Models, Animal; Eosinophils; Female; Humans; Interleukin-5; Lung; Macrophages; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mucus; Phospholipases A; Platelet Activating Factor; Recombinant Proteins

2000
Airway hyperresponsiveness in transgenic mice overexpressing platelet activating factor receptor is mediated by an atropine-sensitive pathway.
    American journal of respiratory and critical care medicine, 2002, Jan-15, Volume: 165, Issue:2

    Topics: Animals; Atropine; Bronchial Diseases; Bronchoconstrictor Agents; Bronchodilator Agents; Disease Models, Animal; Free Radical Scavengers; Methacholine Chloride; Mice; Mice, Transgenic; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Respiratory System; Serotonin; Signal Transduction

2002
Airway eosinophil accumulation on sensory neuropeptide release in a guinea pig model of distilled-water-induced bronchoconstriction.
    Journal of investigational allergology & clinical immunology, 2003, Volume: 13, Issue:2

    Topics: Aerosols; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Disease Models, Animal; Eosinophils; Guinea Pigs; Immunization, Passive; Male; Methacholine Chloride; Piperidines; Platelet Activating Factor; Quinuclidines; Substance P; Water

2003
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
    The Journal of allergy and clinical immunology, 2005, Volume: 116, Issue:3

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2005