1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene e4

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with leukotriene e4 in 22 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (leukotriene e4)	Trials (leukotriene e4)	Recent Studies (post-2010) (leukotriene e4)
9,156	187	552	986	118	122

Protein Interaction Comparison

Protein	Taxonomy	1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)	leukotriene e4 (IC50)
Canalicular multispecific organic anion transporter 1	Rattus norvegicus (Norway rat)		9.83

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (40.91)	18.7374
1990's	10 (45.45)	18.2507
2000's	2 (9.09)	29.6817
2010's	1 (4.55)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Smith, LJ	1
Dollery, CT; Fuller, RW; Taylor, GW; Taylor, IK; Ward, PS	1
Haranaka, K; Haranaka, R; Iimura, F; Sakurai, A; Satomi, N	1
Hamano, S; Ikeda, S; Kikuchi, S; Kojima, M; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y	1
Inagaki, N; Koda, A; Miura, T; Nagai, H; Ohira, K; Xu, QA	1
König, W; Pison, U; Schmit-Neuerburg, KP	1
Northover, AM	1
Hawley, SB; Nieves, AL; Spada, CS; Williams, LS; Woodward, DF	1
Di Marzo, V; Morris, HR; Tippins, JR	3
Lefer, AM; Stahl, GL	1
Antoniw, JW; Piper, PJ; Stanton, AW	1
Lefer, AM; Lefer, DJ; Roth, DM; Smith, JB	1
Braquet, P; Butterly, DW; Coffman, TM; Pirotzky, E; Ruiz, P; Spurney, RF	1
Taylor, IK	1
Barnes, PJ; Carty, TJ; Chung, KF; Eskra, JD; O'Connor, BJ; Uden, S	1
Adachi, M; Horikoshi, S; Idaira, K; Imai, T; Kokubu, F; Mita, S; Okamoto, M; Sugeta, A	1
Achaval, M; Barberà, JA; Chung, KF; Echazarreta, AL; Gómez, FP; Ribas, J; Roca, J; Rodriguez-Roisin, R	1
Ibe, BO; Raj, JU	1
Barberà, JA; Echazarreta, AL; MacNee, W; Peinado, V; Rahman, I; Roca, J; Rodríguez-Roisin, R	1
Gao, CR; Guo, XJ; Yan, XB; Yang, K	1

Reviews

2 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene e4

Article	Year
Bioactive mediators in asthma. Chest, 1992, Volume: 101, Issue:6 Suppl Topics: Asthma; Eicosanoic Acids; Humans; Immunity, Cellular; Leukotriene E4; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; SRS-A; Thromboxane A2	1992
Release of urinary leukotriene E4 in asthmatic subjects: a review. Advances in prostaglandin, thromboxane, and leukotriene research, 1994, Volume: 22 Topics: Asthma; Glucocorticoids; Humans; Leukotriene Antagonists; Leukotriene E4; Lipoxygenase Inhibitors; Platelet Activating Factor	1994

Trials

3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene e4

Article	Year
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:1 Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Bronchoconstriction; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Eicosanoids; Humans; Imidazoles; Leukocyte Count; Leukotriene E4; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Thromboxane B2	1994
Effects of inhaled furosemide on platelet-activating factor challenge in mild asthma. The European respiratory journal, 1999, Volume: 14, Issue:3 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Blood Gas Analysis; Bronchoconstriction; Creatinine; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Furosemide; Humans; Leukocyte Count; Leukotriene E4; Male; Nebulizers and Vaporizers; Platelet Activating Factor; Pulmonary Gas Exchange	1999
Lack of systemic oxidative stress during PAF challenge in mild asthma. Respiratory medicine, 2005, Volume: 99, Issue:5 Topics: Administration, Inhalation; Adult; Analysis of Variance; Antioxidants; Asthma; Bronchi; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Female; Humans; Inflammation Mediators; Leukotriene E4; Lipid Peroxidation; Lipids; Male; Oxidative Stress; Platelet Activating Factor; Respiratory Function Tests	2005

Other Studies

17 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene e4

Article	Year
Inhaled PAF stimulates leukotriene and thromboxane A2 production in humans. Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:4 Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Bronchoconstrictor Agents; Eicosanoids; Endothelium, Vascular; Epoprostenol; Female; Humans; Leukotriene E4; Leukotrienes; Male; Methacholine Compounds; Platelet Activating Factor; Prostaglandins; SRS-A; Stimulation, Chemical; Thromboxane A2	1991
Preventive effect of several drugs against Pseudomonas aeruginosa infection and the toxicity of combined tumor necrosis factor with lipopolysaccharide: relationship between lethality and the arachidonic cascade. Biotherapy (Dordrecht, Netherlands), 1990, Volume: 2, Issue:3 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arachidonic Acid; Arachidonic Acids; Cephamycins; Chromones; Drug Synergism; Drugs, Chinese Herbal; Female; Leukotriene Antagonists; Leukotriene E4; Lipopolysaccharides; Mice; Mice, Inbred Strains; Platelet Activating Factor; Polymyxin B; Pseudomonas Infections; Recombinant Proteins; SRS-A; Tumor Necrosis Factor-alpha	1990
Effect of a thromboxane A2 synthetase inhibitor (OKY-046.HCl) on airway hyperresponsiveness in guinea pigs. European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Airway Resistance; Animals; Antigens; Aspirin; Bronchoalveolar Lavage Fluid; Guinea Pigs; Leukotriene E4; Methacrylates; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Physostigmine; Platelet Activating Factor; Propranolol; Respiratory System; SRS-A; Thromboxane B2; Thromboxane-A Synthase	1990
Effect of CV-3988, a specific antagonist against platelet activating factor, on homologous passive cutaneous anaphylaxis in the mouse ear. Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:5 Topics: Alprostadil; Animals; Antibodies; Blood Vessels; Dinoprostone; Ear, External; Female; Histamine; Immunoglobulin E; Immunoglobulin G; Leukotriene E4; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Permeability; Phospholipid Ethers; Platelet Activating Factor; Serotonin; Skin; SRS-A	1990
On the pathogenesis of adult respiratory distress syndrome--the role of anaphylatoxins, leukotrienes and platelet activating factor. Progress in clinical and biological research, 1987, Volume: 236A Topics: Animals; Capillary Permeability; Complement C5; Complement C5a; Guinea Pigs; Histamine Release; In Vitro Techniques; Leukotriene E4; Mast Cells; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome; SRS-A	1987
Effects of PAF and PAF antagonists on the shape of venous endothelial cells in vitro. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Animals; Calcimycin; Diterpenes; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Furans; Ginkgolides; Guinea Pigs; Lactones; Leukotriene E4; Lysophosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; SRS-A; Vena Cava, Inferior	1989
Platelet-activating factor causes goblet cell depletion in the conjunctiva. European journal of pharmacology, 1989, Sep-01, Volume: 168, Issue:1 Topics: Animals; Capillary Permeability; Conjunctiva; Guinea Pigs; Histamine; In Vitro Techniques; Leukocytes; Leukotriene E4; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; SRS-A	1989
Platelet activating factor-mediated leukotriene biosynthesis in rat lungs: effect of prostaglandins E1 and F1 alpha. Biochemical and biophysical research communications, 1987, Sep-30, Volume: 147, Issue:3 Topics: Alprostadil; Animals; Chromatography, High Pressure Liquid; Cyclic AMP; In Vitro Techniques; Leukotriene E4; Lung; Platelet Activating Factor; Prostaglandins F; Radioimmunoassay; Rats; SRS-A	1987
Effect of vasoactive intestinal peptide and calcitonin gene-related peptide on leukotriene release from guinea pig and rat lung. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B Topics: Animals; Calcimycin; Calcitonin Gene-Related Peptide; Guinea Pigs; In Vitro Techniques; Leukotriene E4; Lung; Neuropeptides; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Vasoactive Intestinal Peptide	1987
Mechanisms of platelet-activating factor-induced cardiac depression in the isolated perfused rat heart. Circulatory shock, 1987, Volume: 23, Issue:3 Topics: Animals; Heart; In Vitro Techniques; Leukotriene E4; Male; Myocardial Contraction; Perfusion; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2; Vascular Resistance	1987
Release of leukotrienes from porcine and human blood vessels by immunological and nonimmunological stimuli. Annals of the New York Academy of Sciences, 1988, Volume: 524 Topics: Animals; Antibodies, Anti-Idiotypic; Blood Vessels; Calcimycin; Cerebral Arteries; Coronary Circulation; Coronary Vessels; Female; Humans; Immunoglobulin E; Immunoglobulin G; Indomethacin; Leukotriene B4; Leukotriene E4; Platelet Activating Factor; Pulmonary Artery; SRS-A; Swine	1988
Neuropeptides and leukotriene release: effect of peptide histidine isoleucine and secretin in platelet activating factor-stimulated rat lung. Neuropeptides, 1987, Volume: 9, Issue:1 Topics: Animals; In Vitro Techniques; Leukotriene E4; Lung; Male; Peptide PHI; Platelet Activating Factor; Rats; Rats, Inbred Strains; Secretin; SRS-A	1987
Potentiation of leukotriene formation in pulmonary and vascular tissue. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:2 Topics: Animals; Blood Vessels; Calcimycin; Cats; Guinea Pigs; In Vitro Techniques; Leukotriene E4; Lung; Meclofenamic Acid; Platelet Activating Factor; Rats; SRS-A; Time Factors	1984
Role of platelet activating factor in kidney transplant rejection in the rat. Kidney international, 1995, Volume: 48, Issue:2 Topics: Animals; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Graft Rejection; Kidney; Kidney Transplantation; Lactones; Leukotriene E4; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Renal Circulation; Thromboxane B2	1995
[Chemotactic activity of human peripheral eosinophils toward leukotriene E4]. Arerugi = [Allergy], 1997, Volume: 46, Issue:7 Topics: Chemotaxis, Leukocyte; Eosinophils; Humans; In Vitro Techniques; Leukotriene E4; Male; Platelet Activating Factor	1997
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor. Experimental lung research, 2001, Volume: 27, Issue:4 Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep	2001
[Changes of prostaglandin D2,carboxypeptidase A3 and platelet activating factor in guinea pig in anaphylactic shock]. Fa yi xue za zhi, 2012, Volume: 28, Issue:3 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anaphylaxis; Animals; Brain; Carboxypeptidases; Case-Control Studies; Disease Models, Animal; Egg Proteins; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Leukotriene E4; Male; Mice; Platelet Activating Factor; Prostaglandin D2; Time Factors	2012