Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene d4

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with leukotriene d4 in 21 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(leukotriene d4)
Trials
(leukotriene d4)
Recent Studies (post-2010) (leukotriene d4)
9,1561875526974297

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)leukotriene d4 (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.0007
Canalicular multispecific organic anion transporter 1Rattus norvegicus (Norway rat)5.48
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.0007
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.0007
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.0039

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (66.67)18.2507
2000's6 (28.57)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Aida, Y; Kasama, T; Takeuchi, N; Tobinaga, S1
Johnston, B; Kanwar, S; Kubes, P1
Ganbo, T; Hisamatsu, K; Inoue, H; Kikushima, K; Kou, J; Kozuka, Y; Mizukoshi, A; Murakami, Y1
Langer, JC; Liebman, SM; Monk, PK; Pelletier, GJ1
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M1
Hasegawa, S; Hirata, A; Hirata, F; Lee, JY; Nomura, A; Sakamoto, T; Uchida, Y1
Chayvialle, JA; Cuber, JC; Minaire, Y; Mion, F1
Farmer, P; Plante, GE; Sirois, MG; Sirois, P1
Kamiya, S; Kanda, M; Kurahashi, K; Matsui, H; Nakamura, S; Shirahase, H; Wada, K1
Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S1
Kannan, Y; Kimura, K; Moriyama, M; Musashi, M; Nishisako, M; Sakurada, K; Shiota, M; Sugano, T1
Koyama, S; Kubo, K; Okubo, Y; Sato, E; Sekiguchi, M1
Beadle, RE; Holmes, EP; Seahorn, TL; Venugopalan, CS1
Takami, M; Tsukada, W1
Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Kitaura, M; Oike, M; Yoshie, O1
Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y1
Ibe, BO; Raj, JU1
Fujiu, T; Kato, M; Kimura, H; Morikawa, A; Suzuki, M1
Hagiwara, K; Kanazawa, M; Kikuchi, I; Nagata, M; Saito, K1
Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H1

Other Studies

21 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene d4

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
The antagonistic effects of khellactones on platelet-activating factor, histamine, and leukotriene D4.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:5

    Topics: Animals; Coumarins; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; In Vitro Techniques; Lactones; Leukotriene D4; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship

1995
Leukotriene C4/D4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo.
    Circulation research, 1995, Volume: 77, Issue:5

    Topics: Animals; Antibodies; Hemodynamics; Kinetics; Leukocytes; Leukotriene C4; Leukotriene D4; Lewis X Antigen; Male; Microscopy; Oligosaccharides; P-Selectin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serine; Sialyl Lewis X Antigen

1995
Effect of ibudilast on ciliary activity of human paranasal sinus mucosa in vitro.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:8

    Topics: Bronchodilator Agents; Cilia; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Mucociliary Clearance; Nasal Mucosa; Paranasal Sinuses; Platelet Activating Factor; Propranolol; Pyridines; Verapamil

1995
Mast cell mediators and peritoneal adhesion formation in the rat.
    The Journal of surgical research, 1995, Volume: 59, Issue:3

    Topics: Animals; Azepines; Disease Models, Animal; Histamine Antagonists; Leukotriene D4; Male; Mast Cells; Methysergide; Ondansetron; Peritoneal Diseases; Platelet Activating Factor; Propionates; Pyrilamine; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Adhesions; Triazoles

1995
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter

1993
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle.
    Biochemical and biophysical research communications, 1994, Sep-30, Volume: 203, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Gene Expression Regulation; GTP-Binding Proteins; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Leukotriene D4; Lipids; Lipoxygenase Inhibitors; Masoprocol; Muscle, Smooth; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Thromboxane A2; Trachea; Vasoconstrictor Agents

1994
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor.
    Gut, 1994, Volume: 35, Issue:4

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Culture Techniques; Edetic Acid; Eicosanoids; Ileum; Indomethacin; Kinetics; Leukotriene B4; Leukotriene D4; Male; Permeability; Platelet Activating Factor; Rats; Rats, Wistar

1994
Platelet activating factor modulates peptidoleukotriene effects on the permeability of bovine aortic endothelial cell to albumin.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Animals; Aorta; Cattle; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vascular; Leukotriene C4; Leukotriene D4; Platelet Activating Factor; Regression Analysis; Serum Albumin, Bovine

1993
Effects of 1-[3-(4-benzhydryl-1-piperazinyl)propyl]-3- (1H-imidazol-1-ylmethyl)-1H-indole-6-carboxylic acid with thromboxane A2 synthetase inhibitory and H1-blocking activities on anaphylactic bronchospasm.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:11

    Topics: Anaphylaxis; Animals; Bronchial Spasm; Bronchoconstriction; Enzyme Inhibitors; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indoles; Leukotriene D4; Lung; Male; Methacrylates; Platelet Activating Factor; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Trachea

1996
Effect of Y-24180, a long-acting antagonist to platelet-activating factor (PAF), on PAF-induced reactions: a relationship between the partial structure of the compound and its duration of the action.
    Pharmacology, 1997, Volume: 54, Issue:5

    Topics: Acetylcholine; Administration, Oral; Animals; Azepines; Binding Sites; Blood Platelets; Bradykinin; Bronchial Hyperreactivity; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Injections, Intravenous; Leukotriene D4; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Structure-Activity Relationship; Triazoles

1997
Modulation of platelet activating factor-induced glycogenolysis in the perfused rat liver after administration of endotoxin in vivo.
    Journal of biochemistry, 1998, Volume: 123, Issue:1

    Topics: Animals; Eicosanoids; Endotoxemia; Glycogen; Leukotriene Antagonists; Leukotriene D4; Lipopolysaccharides; Liver; Male; Membrane Proteins; Oxygen Consumption; Perfusion; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2

1998
Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Acetylcholine; Animals; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cholinergic Antagonists; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukins; Leukotriene B4; Leukotriene C4; Leukotriene D4; Macrophages, Alveolar; Monocytes; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Substance P

1998
Responses of guinea-pig lung parenchymal strips to tracheobronchial lavage fluid from horses affected with summer pasture-associated obstructive pulmonary disease.
    Veterinary research communications, 1998, Volume: 22, Issue:7

    Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Dinoprostone; Guinea Pigs; Histamine; Horse Diseases; Horses; In Vitro Techniques; Leukotriene D4; Lung; Lung Diseases, Obstructive; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Poaceae; Prostaglandin Antagonists; Quinolines; Reference Values; Seasons; Trachea; Xanthenes; Xanthones

1998
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
    European journal of pharmacology, 1999, Feb-05, Volume: 366, Issue:2-3

    Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase

1999
Effect of eotaxin and platelet-activating factor on airway inflammation and hyperresponsiveness in guinea pigs in vivo.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:6

    Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Cytokines; Eosinophilia; Eosinophils; Guinea Pigs; Interleukin-5; Leukocyte Count; Leukotriene D4; Male; Platelet Activating Factor

2000
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
    Respiration; international review of thoracic diseases, 2001, Volume: 68, Issue:1

    Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2

2001
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor.
    Experimental lung research, 2001, Volume: 27, Issue:4

    Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep

2001
Inhibition of human eosinophil activation by a cysteinyl leukotriene receptor antagonist (pranlukast; ONO-1078).
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2003, Volume: 40, Issue:4

    Topics: Cell Degranulation; Chromones; Eosinophils; Humans; Immunity, Cellular; Leukotriene Antagonists; Leukotriene D4; Macrophage-1 Antigen; Membrane Proteins; Phorbol Esters; Platelet Activating Factor; Receptors, Leukotriene; Superoxides

2003
Effect of the cysteinyl leukotriene antagonist pranlukast on transendothelial migration of eosinophils.
    International archives of allergy and immunology, 2005, Volume: 137 Suppl 1

    Topics: Adult; Cell Movement; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Chromones; Drug Interactions; Endothelial Cells; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Platelet Activating Factor; Receptors, Leukotriene

2005
Effects of platelet-activating factor, thromboxane A2 and leukotriene D4 on isolated perfused rat liver.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:1-2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Hemodynamics; In Vitro Techniques; Leukotriene D4; Liver; Male; Organ Size; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction

2006