1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with leukotriene b4 in 476 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (leukotriene b4) | Trials (leukotriene b4) | Recent Studies (post-2010) (leukotriene b4) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 5,886 | 232 | 717 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | leukotriene b4 (IC50) |
|---|---|---|---|
| Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.0019 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 137 (28.78) | 18.7374 |
| 1990's | 279 (58.61) | 18.2507 |
| 2000's | 49 (10.29) | 29.6817 |
| 2010's | 11 (2.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hugli, TE; Jagels, MA | 1 |
| Asako, H; Baethge, BA; Granger, DN; Kubes, P; Wolf, RE | 2 |
| Holgate, ST; Morland, CM; Roche, WR; Wilson, SJ | 1 |
| Cromwell, O; Kay, AB; Kurihara, K; Sehmi, R; Waltmann, P; Wardlaw, AJ | 1 |
| Healy, CT; Moreira-Ludewig, R | 1 |
| Coëffier, E; Hidi, R; Vargaftig, BB | 1 |
| Haston, WO; Morrissey, MM; Quintavalla, JC; Rediske, JJ; Seligman, B | 1 |
| Asako, H; Granger, DN; Kubes, P; Wallace, J; Wolf, RE | 1 |
| Abbas, MK; Carolan, EJ; Casale, TB | 1 |
| Frei, K; Hennet, T; Peterhans, E; Ziltener, HJ | 1 |
| de Lima, WT; Jancar, S; Sirois, P | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Catania, A; Hiltz, ME; Lipton, JM | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Tuomisto, L; Vapaatalo, H | 1 |
| Brady, HR; Brenner, BM; Denton, MD; Jimenez, W; Palliser, D; Takata, S | 1 |
| Carolan, EJ; Casale, TB | 1 |
| Donigi-Gale, D; Edwards, R; Norman, KE; Rossi, AG; Shoupe, TS; Williams, TJ | 1 |
| Müller, S; Nigam, S | 1 |
| Damtew, B; Spagnuolo, PJ | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 3 |
| Cunningham, FM; Foster, AP; Lees, P | 1 |
| Askaa, J; Bjerrum, OW; Borregaard, N; Kjeldsen, L | 1 |
| Goodman, MA; Lawrence-Brown, MM; Prendergast, FJ; Rocchetta, S; Sieunarine, K | 1 |
| Heckenberger, R; Schrör, K | 1 |
| Schatz-Munding, M; Ullrich, V | 1 |
| Kimura, I; Takahashi, K; Tanimoto, Y | 1 |
| Ju, DW; Rui, YC; Sun, DX; Zeng, GQ | 1 |
| Dubertret, L; Michel, L | 2 |
| Bienvenu, K; Granger, DN; Russell, J | 1 |
| Asako, H; Granger, DN; Korthuis, RJ; Wolf, RE | 1 |
| Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T | 1 |
| Agrawal, DK; Numao, T | 1 |
| Baggiolini, M; Dahinden, CA; de Weck, AL; Wirthmueller, U | 1 |
| Akutsu, I; Fukuda, T; Makino, S; Numao, T | 1 |
| Bruijnzeel, PL; Koenderman, L; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Faccioli, LH; Kay, AB; Moqbel, R; Nourshargh, S; Sehmi, R; Williams, FM; Williams, TJ | 1 |
| Coëffier, E; Joseph, D; Vargaftig, BB | 4 |
| Ferrell, JB; Fleisher, LN; McGahan, MC; Smith, MG | 1 |
| Jacobson, DP; O'Flaherty, JT; Redman, JF; Rossi, AG | 2 |
| Chaussade, S; Denizot, Y | 1 |
| Hu, W; Kinnaird, AA; Man, RY | 1 |
| Becker, EL; Huang, CK; Molski, TF; Sha'afi, RI; Stevens, T; Yamazaki, M | 1 |
| Johnson, JA; Smith, DM; Turner, RA | 1 |
| Beilin, LJ; Croft, KD; Moulton, C; Proudfoot, J | 1 |
| Borgeat, P; Palmantier, R | 2 |
| Harvath, L | 1 |
| Aktories, K; Grimminger, F; Just, I; Seeger, W; Sibelius, U | 1 |
| Aktories, K; Grimminger, F; Seeger, W; Sibelius, U; Suttorp, N | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Vapaatalo, H | 1 |
| Johnson, HG; McNee, ML | 1 |
| Gay, JC; Murray, JJ | 1 |
| Hirafuji, M; Shinoda, H | 1 |
| Didsbury, J; Snyderman, R | 1 |
| Ernest, MJ; Fruman, DA; Gamache, DA | 1 |
| Anglin, CP; Clapp, NK; Fretland, DJ; Gaginella, TS; Hansard, RM; Henke, MA; Walsh, RE; Widomski, DL | 1 |
| Chang, JY; Glaser, KB; Lock, YW | 1 |
| Rola-Pleszczynski, M | 1 |
| Su, SN; Tsai, JJ; Wang, SR; Yu, LN | 1 |
| Arita, H; Hanasaki, K; Kato, T; Kishino, J | 1 |
| Horii, T; Kobayashi, Y; Okuyama, H; Saito, K; Satouchi, K; Watanabe, S; Yoshida, Y | 1 |
| Coyle, AJ; Lefort, J; Vargaftig, BB | 1 |
| Barrowman, JA; Gaginella, T; Granger, DN; Grisham, MB; Kubes, P | 1 |
| Fernandez-Gallardo, S; Garcia, C; Garcia, MC; Gijon, MA; Nieto, ML; Sanchez Crespo, M | 1 |
| Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D | 3 |
| Flower, RJ; Peers, SH | 1 |
| Alexander, JW; Noel, JG; Ogle, CK; Ogle, JD; Sramkoski, RM | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Borgeat, P; Braquet, M; Braquet, P; Krump, E; McColl, SR; Naccache, PH; Poubelle, PE | 1 |
| Bass, DA; Bauldry, SA; Cousart, SL; McCall, CE | 1 |
| Ahnfelt-Rønne, I; Kirstein, D; Larsen, CG; Skak-Nielsen, T; Thestrup-Pedersen, K; Thomsen, HK; Thomsen, MK | 1 |
| Distler, A; Fassbender, M; Hilgenstock, G; Seifert, R | 1 |
| De Nichilo, M; Harris, T; Lopez, AF; Stewart, AG | 1 |
| Kanaho, Y; Kanoh, H; Nozawa, Y; Saitoh, K | 1 |
| Hara, A; Ikeda, M; Kaneko, H; Shiba, T; Takeuchi, S; Yoshida, H | 1 |
| Bonne, C; Meynier, F; Muller, A | 1 |
| Kownatzki, E; Uhrich, S | 1 |
| Borgeat, P; Braquet, M; Krump, E; McColl, SR; McDonald, PP; Naccache, PH | 1 |
| Dahinden, CA; Kurimoto, Y; Wirthmüller, U | 1 |
| Iikura, Y; Kay, AB; Moqbel, R; Nagakura, T; Walsh, GM | 1 |
| Lerner, R; Lindström, P; Palmblad, J; Patarroyo, M | 1 |
| Lerner, R; Lindström, P; Palmblad, J | 2 |
| Chambaut-Guerin, AM; Delbourg, I; Ribier, A; Thomopoulos, P; Ventura, MA | 1 |
| Christophers, E; Morita, E; Schröder, JM | 2 |
| Geissler, FT; Henderson, WR; Kuzan, FB | 1 |
| Cerletti, C; Chen, ZM; De Gaetano, G; Del Maschio, A; Evangelista, V; Rajtar, G | 1 |
| DiPersio, JF; Gasson, JD; Golde, DW | 1 |
| Keenan, CM; Wallace, JL | 1 |
| Fleisher, LN; Joyce, PB; Olson, NC | 1 |
| Grinstein, S; Lu, DJ | 1 |
| Dahinden, CA; de Weck, AL; Wirthmueller, U | 1 |
| Arai, Y; Kawamura, M | 1 |
| Austen, KF; Benincaso, AI; Coblyn, JS; Larkin, JK; Sperling, RI; Weinblatt, ME | 1 |
| Croft, KD; Ysrael, MC | 1 |
| Bazan, NG; Quinn, JH | 1 |
| Tai, HH; Tanizawa, H | 2 |
| Beauseigle, D; Gilbert, C; McColl, SR; Naccache, PH | 1 |
| Ackerman, Z; Karmeli, F; Ligumsky, M; Rachmilewitz, D | 1 |
| Atkins, PC; Moskovitz, AR; Taylor, MB; von Allmen, C; Zweiman, B | 1 |
| Beilin, LJ; Croft, KD; Masarei, J; Rouse, I; Vandongen, R | 1 |
| Bonak, VA; Caon, AC; Gaudry, M; Gilbert, C; Huang, CK; McColl, SR; Naccache, PH; Umezawa, K | 1 |
| Careaga-Houck, M; Sprecher, H | 1 |
| Fox, CC; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Schleimer, RP | 1 |
| Brain, SD; Williams, TJ | 1 |
| Håkansson, L; Venge, P; Westerlund, D | 1 |
| Hedqvist, P; Lindbom, L; Ohlén, A; Raud, J; Thureson-Klein, A | 1 |
| Abraham, WM; Wanner, A | 1 |
| Ney, P; Schrör, K | 1 |
| Hecker, G; Ney, P; Schröder, H; Schrör, K | 1 |
| Franson, RC; Rosenthal, MD; Vishwanath, BS | 1 |
| Hallam, TJ; Jacob, R; Merritt, JE | 1 |
| Laplante, C; Marceau, F; Tremblay, B | 1 |
| Böhme, E; Schmidt, HH; Seifert, R | 1 |
| Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P | 1 |
| O'Flaherty, JT; Tessner, TG; Wykle, RL | 1 |
| Atkins, PC; Goetzl, EJ; Ratnoff, WD; Shalit, M; Valone, FH; Zweiman, B | 1 |
| Dinya, Z; Farkas, T; Gergely, P; Sipka, S; Szegedi, G | 1 |
| Braquet, P; Jancar, S; Sirois, P | 3 |
| Hsueh, W; Needleman, P; Spaethe, SM | 1 |
| Csatò, M; Czarnetzki, BM | 1 |
| Iikura, Y; Nagakura, T; Walsh, GM | 1 |
| Beneker, C; Meisters, TM; Pover, P; Raaijmakers, JA; van Geffen, EC | 1 |
| Heidel, JR; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Fondacaro, JD; Griswold, DE; Rachmilewitz, D; Schwartz, LW; Simon, PL; Wasserman, MA | 1 |
| Bissonnette, E; Dubois, C; Rola-Pleszczynski, M | 1 |
| Arnoux, B; Benveniste, J; Miadonna, A; Sala, A; Tedeschi, A; Zanussi, C | 1 |
| Baglioni, C; Bussolino, F; Camussi, G; Tetta, C | 1 |
| Borgeat, P; Caon, AC; McColl, SR; Naccache, PH | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Fitzgerald, MF; Parente, L; Whittle, BJ | 1 |
| O'Flaherty, JT; Rossi, AG | 2 |
| Omann, GM; Porasik, MM; Sklar, LA | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Jacobson, D; O'Flaherty, JT | 1 |
| Kraemer, R; Mullane, KM | 1 |
| Chilton, FH; Cluzel, M; Undem, BJ | 1 |
| Fradin, A; Henson, PM; Maclouf, J; Murphy, RC; Vausbinder, L; Zirrolli, JA | 1 |
| Franson, RC; Rosenthal, MD | 1 |
| Bian, RL; Hong, JL; Zhou, HL | 1 |
| Ellis, JM; Marx, MH; O'Flaherty, JT; Piantadosi, C; Redman, JF; Schmitt, JD; Surles, JR; Wykle, RL | 1 |
| Baggiolini, M; Deranleau, DA; Dewald, B; Kernen, P; von Tscharner, V; Wymann, MP | 1 |
| Henderson, WR; Martin, TR; Merritt, TL; Raugi, G | 1 |
| Fitzgerald, MF; Moncada, S; Parente, L | 1 |
| Dallob, A; Goldenberg, MM; Guindon, Y | 1 |
| Borgeat, P; Braquet, P; Harczy, M; Maclouf, J; Pradelles, P; Sirois, P | 1 |
| Anderson, GP; Fennessy, MR; Stewart, AG | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| Goto, F | 1 |
| Bienvenu, P; Braquet, M; Ducousso, R; Gerasimo, P; Kergonou, JF; Lavaud, P; Mathieu, J | 1 |
| Jacobson, D; O'Flaherty, JT; Redman, J | 1 |
| Justen, JM; Sam, LM; Smith, RJ | 2 |
| Daniel, EE; Jury, J; O'Byrne, P; Pashley, M; Serio, R | 1 |
| Brain, SD; Hellewell, PG; Jose, PJ; Nourshargh, S; Rampart, M; Williams, TJ | 1 |
| Antoniw, JW; Piper, PJ; Stanton, AW | 1 |
| Behrens, T; Goodwin, JS | 1 |
| Abraham, WM | 1 |
| Daniel, EE; Serio, R | 1 |
| Crooke, ST; Foley, JJ; Mong, S; Sarau, HM; Winkler, JD | 1 |
| Grinstein, S; Nasmith, PE | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Camp, RD; Greaves, MW | 1 |
| Atkins, PC; Shalit, M; Von Allmen, C; Zweiman, B | 1 |
| MacNaughton, WK; Wallace, JL | 1 |
| MacIntyre, DE; McMillan, RM; Rossi, AG | 1 |
| Caravella, SJ; Clark, DA; McNeill, H; Miller, MJ; Mullane, KM | 1 |
| Errasfa, M; Fradin, A; Poincelot-Canton, B; Rothhut, B; Russo-Marie, F | 1 |
| Agrawal, DK; Tamura, N; Townley, RG | 1 |
| Barden, A; Beilin, LJ; Codde, JP; Croft, KD; Vandongen, R | 1 |
| Braquet, P; Sirois, P; Soufir, M; Touvay, C; Vilain, B | 1 |
| Sudan, BJ | 1 |
| Dahl, ML | 1 |
| O'Flaherty, JT | 2 |
| Baggiolini, M; Dewald, B | 3 |
| Bruynzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Kaveshnikova, BF | 1 |
| Issekutz, AC; Ripley, M; Rochon, Y | 1 |
| Damas, J | 1 |
| Aizawa, H; Chung, KF; Evans, TW; Leikauf, GD; Nadel, JA; Ueki, IF | 1 |
| Klein-Knoeckel, D; Zimmerman, GA | 1 |
| Deacon, RW; Farley, C; Handley, DA; Saunders, RN | 1 |
| Becker, EL | 1 |
| Pickett, WC; Ramesha, CS | 1 |
| Kikawa, Y; Shigematsu, Y; Sudo, M | 1 |
| Del Maschio, A; Iliou, JP; Maclouf, J | 1 |
| Dondero-Zahn, C; Nytko, D; Pickett, WC; Ramesha, C | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Bonhomme, B; Braquet, P; Doly, M; Meyniel, G | 1 |
| Braquet, P; Clostre, F; Etienne, A; Touvay, C; Vilain, B | 1 |
| Chavis, C; Crastes De Paulet, A; Damon, M; Godard, P; Michel, FB | 1 |
| Cromwell, O; Kay, AB; Moqbel, R; Wardlaw, AJ | 1 |
| Stimler-Gerard, NP | 1 |
| Nishihira, J; O'Flaherty, JT | 1 |
| Agrawal, DK; Suliaman, FA; Tamura, N; Townley, RG | 1 |
| Henderson, WR | 1 |
| Becker, EL; Kanaho, Y; Matsumoto, T; Molski, TF; Sha'afi, RI | 1 |
| Bodmer, JL; Bray, MA; McKearn-Smith, C; Metz-Virca, G; Virca, GD | 1 |
| Feuerstein, G; Hallenbeck, JM | 1 |
| Akerman, KE; Hartiala, KT; Scott, IG; Viljanen, MK | 1 |
| Piper, PJ; Stewart, AG | 1 |
| McIntyre, TM; Prescott, SM; Sisson, JH; Zimmerman, GA | 1 |
| Benveniste, J; Dubertret, L; Mencia-Huerta, JM; Michel, L | 1 |
| Bureau, M; Joseph, D; Vargaftig, BB | 1 |
| Moodley, I; Stuttle, A | 1 |
| Filep, J; Földes-Filep, E | 1 |
| Molski, TF; Sha'afi, RI | 1 |
| Parker, CW | 1 |
| Piper, PJ; Stanton, AW; Stewart, AG | 1 |
| Augustine, NH; Hill, HR; McFall, TL; Zimmerman, GA | 1 |
| Baggiolini, M; Deranleau, DA; von Tscharner, V; Wymann, MP | 1 |
| Colditz, IG; Movat, HZ | 1 |
| Thomson, DM | 1 |
| Gorman, RR; Hopkins, NK; Schaub, RG | 1 |
| Bach, MK | 1 |
| Bohn, A; Borgeat, P; Bremm, KD; Brom, HJ; Crea, AE; Falsone, G; König, W; Pison, U; Spur, B; Theobald, K | 1 |
| Lees, CJ; McCall, CE; O'Flaherty, JT; Shewmake, T; Thomas, MJ; Wykle, RL | 1 |
| Hammett, MJ; Love, SH; McCall, CE; O'Flaherty, JT; Shewmake, TB; Thomas, MJ; Wykle, RL | 1 |
| Gorman, RR; Lin, AH; Morton, DR | 1 |
| Vargaftig, BB | 1 |
| Ford-Hutchinson, AW | 1 |
| Gorman, RR; Hopkins, NK; Lin, AH; Morton, DR | 1 |
| Gorman, RR; Hopkins, NK; Lin, AH | 2 |
| Goetzl, EJ; Kaplan, AP | 1 |
| Austen, KF; Lewis, RA; Mencia-Huerta, JM; Razin, E | 1 |
| Czarnetzki, B | 1 |
| Austen, KF; Schwartz, LB | 1 |
| McCall, CE; O'Flaherty, JT; Thomas, MJ; Wykle, RL | 1 |
| Bowman, BJ; Iden, SS; Smith, RJ | 1 |
| Davidson, D; Tan, ND | 1 |
| Grisham, MB | 1 |
| Akutsu, I; Fukuda, T; Makino, S; Motojima, S; Numao, T; Toda, M | 1 |
| Inagaki, N; Iwama, T; Kitagaki, K; Koda, A; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Newton, RC; Vaddi, K | 1 |
| Adams, JL; Badger, A; Bolognese, B; Chabot-Fletcher, M; Flamberg, PL; Hall, RH; Marshall, LA; Roshak, A; Sung, CM; Winkler, JD | 1 |
| Hoffman, JF; Linderman, JJ; Omann, GM; Rengan, R | 1 |
| Brocchieri, A; Grignani, G; Moroni, M; Porta, C; Saporiti, A | 1 |
| Koyama, S; Rennard, SI; Robbins, RA | 1 |
| Borgeat, P; Krump, E; Naccache, PH; Pouliot, M | 1 |
| Keuskamp, ZJ; Madretsma, GS; Van Dijk, JP; Zijlstra, FJ | 1 |
| Iwamoto, I; Tomioka, H; Tomoe, S; Yoshida, S | 1 |
| Asmawi, MZ; Kankaanranta, H; Moilanen, E; Vapaatalo, H | 1 |
| Iwamoto, I; Tomoe, S; Yoshida, S | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Chandel, B; Deshpande, Y; Kaminski, DL; Kulkarni, A; Longo, WE; Niehoff, M; Polities, G; Vernava, AM | 1 |
| Chuluyan, HE; Issekutz, AC; Lopes, N | 1 |
| Bratt, J; Lerner, R; Palmblad, J; Ringertz, B | 1 |
| Eskafi, S; Müller, S; Nigam, S; Zhang, H | 1 |
| Colotta, F; Fadlon, EJ; Mantovani, A; Matteucci, C; Orlando, S; Sozzani, S | 1 |
| Schröder, JM; Schwenk, U | 1 |
| Casale, TB; Erger, RA | 1 |
| Pettipher, ER; Salter, ED; Showell, HJ | 1 |
| Autore, G; Capasso, F; Di Carlo, G; Izzo, AA; Maiello, FM; Mascolo, N | 1 |
| Kankaanranta, H; Moilanen, E | 1 |
| Bolanowski, MA; Nourshargh, S; Sanz, MJ; Weg, VB | 1 |
| Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Au, BT; Hellewell, PG; Rossi, AG; Teixeira, MM; Williams, TJ | 1 |
| Tsai, JJ; Wang, SR; Wang, TF | 1 |
| Ho, CY; Tsai, JJ; Wang, SR | 1 |
| Chandel, B; Deshpande, Y; Kaminski, DL; Li, AP; Longo, WE; Stratton, MD; Vernava, AM | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Benoit, JN; Granger, DN; Harris, NR | 1 |
| de la Cruz, C; de Nicoläs, R; Egido, J; González, E; Herrero-Beaumont, G | 1 |
| Bienvenu, K; Granger, DN; Harris, N | 1 |
| Ackerman, Z; Eliakim, R; Karmeli, F; Rachmilewitz, D; Stalnikowicz, R | 1 |
| Lerner, R | 1 |
| Blackburn, WD; Chatham, WW; Turkiewicz, A | 1 |
| Kalmar, JR; Van Dyke, TE | 1 |
| Kimura, J; Namura, Y; Shio, H | 1 |
| Alverez, J; Garcia-Sancho, J; Montero, M | 1 |
| Adams, J; Borgeat, P; Dinallo, RM; Farina, PR; Graham, AG; Hansen, G; Hoffman, AF; Miao, CK; Nadeau, M; Watrous, JM | 1 |
| Cordes, JF; O'Flaherty, JT | 1 |
| Chen, LL; Kreutzer, DL; Mann, EA; Spiro, JD | 1 |
| Bignold, LP; Harkin, DG | 1 |
| Borgeat, P; Braquet, P; McColl, SR; McDonald, PP | 1 |
| Boichot, E; Braquet, P; Carré, C; Kyriacopoulos, F; Lagente, V; Mencia-Huerta, JM | 1 |
| Cho, SK; Kane, GC; Kim, CJ; Koh, YY; Peters, SP; Zangrilli, JG | 1 |
| Engels, F; Henricks, PA; Nijkamp, FP; van de Velde, MJ | 1 |
| de Boer, M; Koenderman, L; Kuijpers, TW; Mascart-Lemone, F; Roos, D; van Zwieten, R; Verhoeven, AJ | 1 |
| Iwama, T; Koda, A; Nagai, H | 1 |
| Anderson, DC; Granger, DN; Kvietys, PR; McIntire, LV; Takemura, T; Wolf, RE; Yoshida, N | 1 |
| Javors, MA; Olson, MS; Zhou, W | 1 |
| Kankaanranta, H; Kirkkola, AL; Moilanen, E; Nieminen, MM; Vapaatalo, H | 1 |
| Beusenberg, FD; Bonta, IL; van Amsterdam, JG | 1 |
| Catania, A; Ceriani, G; Lipton, JM; Macaluso, A | 1 |
| Connelly, PA; Farrell, CA; Richard, S; Shaw, AS; Showell, HJ | 1 |
| Belogi, L; Cavallo, G; Croce, C; Guida, G; Modesti, A; Santiangeli, C; Tubaro, E | 1 |
| Marshall, CJ; Saklatvala, J; Thompson, HL | 1 |
| Anderson, DC; Granger, DN; Holt, JW; Miyasaka, M; Paulson, JC; Rusche, JR; Tamatani, T; Todd, RF; Zimmerman, BJ | 1 |
| Campos, MG; Church, MK; Joseph, D; Lefort, J; Pretolani, M; Ruffié, C; Vargaftig, BB | 1 |
| Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV | 1 |
| Chayvialle, JA; Cuber, JC; Minaire, Y; Mion, F | 1 |
| Gaboury, J; Granger, DN; Kubes, P; Reinhardt, P; Woodman, RC | 1 |
| Grinstein, S; Laneuville, O; Nigam, S; Pace-Asciak, CR; Reynaud, D | 2 |
| Frojmovic, MM; Rochon, YP | 1 |
| Borgeat, P; McColl, SR; McDonald, PP; Pouliot, M | 1 |
| Larsson, SH; Lerner, R; Palmblad, J | 1 |
| Anglin, C; Carson, R; Clapp, N; Fretland, D; Hansard, R; Henke, M; Walsh, R; Widomski, D | 1 |
| Levine, BA; Olson, MS; Zhou, W | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Casale, TB; Erger, RA; Little, MM | 1 |
| Asako, H; Granger, DN; Wolf, RE | 1 |
| Chilton, FH; Fonteh, AN; Hubbard, WC; Patel, M; Triggiani, M | 1 |
| Goff, AK; Slama, H; Vaillancourt, D | 1 |
| Fruchtmann, R; Hatzelmann, A; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Lobb, RR; Nourshargh, S; Weg, VB; Williams, TJ | 1 |
| Austen, KF; Benincaso, AI; Knoell, CT; Larkin, JK; Robinson, DR; Sperling, RI | 1 |
| Jones, CJ; MacIntyre, DE; McMillan, RM; Rossi, AG | 1 |
| Colditz, IG; Mulder, K | 1 |
| Beilin, LJ; Croft, KD | 1 |
| Jamieson, D; Lin, Y | 1 |
| Chilton, FH; Hubbard, WC; Sung, CM; Winkler, JD | 1 |
| Arndt, H; Granger, DN; Smith, CW | 1 |
| Izumi, T; Mori, M; Shimizu, T | 1 |
| Hirata, K; Kanazawa, H; Kurihara, N; Takeda, T; Terakawa, K | 1 |
| Azzari, C; Baldi, E; Carloni, V; Gentilini, P; Gresele, P; Laffi, G; Marra, F; Rossi, ME | 1 |
| Heimburger, M; Lerner, R; Palmblad, J | 1 |
| Blair, IA; Christman, BW; Christman, JW; Dworski, R; Prakash, C | 1 |
| Arndt, H; Granger, DN; Kubes, P; Kurose, I; Russell, JB | 1 |
| Castagliuolo, I; Eliakim, R; Joshi, MA; Karmeli, F; Kelly, CP; LaMont, JT; O'Keane, CJ; Pothoulakis, C; Rachmilewitz, D | 1 |
| Donigi-Gale, D; Granger, DN; McKnight, GW; Shoupe, TS; Wallace, JL | 1 |
| Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Samuelsson, J | 1 |
| Tool, AT; Verhoeven, AJ | 1 |
| Ikemura, T; Ishii, H; Kase, H; Kitamura, S; Manabe, H; Miki, I; Ohmori, K; Onuma, K; Sasaki, Y; Sato, S | 1 |
| Lorini, M; Miadonna, A; Milazzo, N; Sala, A; Tedeschi, A | 1 |
| Hedqvist, P; Lindbom, L; Raud, J; Thorlacius, H; Xie, X | 1 |
| Advani, SH; Bhisey, AN; Kumar, A; Naik, NR; Radhika, V; Thennarasu, S | 1 |
| Hellewell, PG; Macari, DM; Teixeira, MM | 1 |
| Arakawa, N; Endo, S; Inada, K; Nakae, H; Ogawa, M; Shimamura, T; Suzuki, T; Takakuwa, T; Taniguchi, S; Teraoka, H; Yaegashi, Y; Yamada, Y | 1 |
| Kohno, S; Nabe, T; Yamamura, H | 2 |
| Anderson, DC; Granger, DN; Kurose, I; Miyasaka, M; Wolf, R | 1 |
| Koyama, S; Kubo, K; Nomura, H; Sato, E; Sekiguchi, M | 1 |
| Bauldry, SA; Wooten, RE | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| de Koster, BM; Elferink, JG | 1 |
| Alves, AC; Cordeiro, RS; Cruz, HN; Diaz, BL; Lagente, V; Martins, MA; Pires, AL; Serra, MF | 1 |
| Hilger, RA; Köller, M; König, W | 1 |
| Williams, FM | 1 |
| Closa, D; Gelpí, E; Hotter, G; Pi, F; Prats, N; Roselló-Catafau, J | 1 |
| Bae, SJ; Hakugawa, J; Katayama, I; Tanaka, Y; Vinuesa, MA | 1 |
| Andrade, LE; Jancar, S; Rocha, FA; Russo, M | 1 |
| Arnold, F; Cherry, GW; He, CF | 1 |
| Patarroyo, M; Salcedo, R; Wasserman, K | 1 |
| Giembycz, MA; Hellewell, PG; Lindsay, MA; Teixeira, MM | 1 |
| Cunningham, FM; Foster, AP; McCabe, PJ; Sanjar, S | 1 |
| Delalandre, A; Filep, JG; Földes-Filep, E; Payette, Y | 1 |
| Gerritsen, ME; Granger, DN; Henninger, DD | 1 |
| Barnett, CC; Moore, EE; Moore, FA; Partrick, DA; Silliman, CC | 1 |
| Granger, DN; Kimura, M; Kurose, I; Russell, J | 1 |
| Hellewell, PG; Kunkel, SL; Lukacs, NW; Proudfoot, AE; Teixeira, MM; Wells, TN; Williams, TJ | 1 |
| Barbara, JA; Chilvers, ER; Condliffe, AM; Dransfield, I; Dunkley, SA; Haslett, C; Lopez, AF; Murray, J; Van Ostade, X | 1 |
| Bai, T; Jacobson, M; Knight, D; Rocchini, C; Walker, B; Zheng, X | 1 |
| Anderson, J; Chen, E; Shamsuddin, M; Smith, LJ | 1 |
| Stapleton, F; Thakur, A; Willcox, MD | 1 |
| Fukumura, M; Koide, K; Shindo, K | 2 |
| Boni, P; Castellucci, A; Evangelista, S; Joseph, D; Manzini, S; Perretti, F; Pretolani, M; Renzetti, AR; Subissi, A | 1 |
| Borgeat, P; Boudreault, S; Krump, E; Surette, ME | 1 |
| Johnson, JL; Moore, EE; Offner, PJ; Partrick, DA; Silliman, CC; Tamura, DY | 1 |
| al-Hage, M; Ezeamuzie, CI; Nwankwoala, RN | 1 |
| Kawauchi, Y; Masuho, Y; Takasaki, J | 1 |
| Koyama, S; Kubo, K; Okubo, Y; Sato, E; Sekiguchi, M | 1 |
| Białasiewicz, P; Król, M; Nowak, D | 1 |
| Akisü, M; Baka, M; Coker, I; Hüseyinov, A; Kültürsay, N | 1 |
| Alves, AC; Cordeiro, RS; e Silva, PM; Lagente, V; Martins, MA; Pires, AL | 1 |
| Thakur, A; Willcox, MD | 1 |
| Burke-Gaffney, A; Hellewell, PG | 1 |
| Borojevic, R; Cordeiro, R; Machado, J; Martins, M; Perez, S; Silva, P | 1 |
| Denizot, Y; Praloran, V; Trimoreau, F | 1 |
| Ito, K; Nakagawa, T; Tadokoro, K; Takafuji, S | 1 |
| Fukamachi, H; Gleich, GJ; Ishikawa, M; Kawai, H; Kita, H; Miura, T; Motegi, Y; Ohashi, H | 1 |
| Izumi, T; Koyama, S; Kubo, K; Miura, M; Nagai, S; Nomura, H; Sato, E; Yamashita, T | 3 |
| Izumi, T; Koyama, S; Kubo, K; Masubuchi, T; Nagai, S; Sato, E; Sekiguchi, M; Takamizawa, A | 1 |
| Gravel, S; Halwani, F; Powell, WS | 1 |
| Coghe, J; Deby-Dupont, G; Lekeux, P; Uystepruyst, C; Van de Weerdt, ML | 1 |
| Alonso, A; Bayón, Y; Hernández, M; Nieto, ML; Sánchez Crespo, M | 1 |
| Borgeat, P; Krump, E | 1 |
| Aydogdu, S; Caglayan, S; Coker, I; Göksen, D; Hüseyinov, A; Kütükçüler, N; Yagci, RV | 1 |
| Denizot, Y; Feiss, P; Nathan, N | 1 |
| Rainsford, KD | 1 |
| Erl, W; Weber, C; Weber, KS; Weber, PC | 1 |
| Elizalde, JI; Granger, DN; Panés, J; Piqué, JM; Salas, A | 1 |
| Anderson, DC; Bosch, J; Casadevall, M; Granger, DN; Panés, J; Pérez-del-Pulgar, S; Piqué, JM; Pizcueta, P; Salas, A | 1 |
| Allen, A; Davies, D; Haskard, DO; Larbi, K; Lobb, RR; Nourshargh, S; Sanz, M; Weg, VB | 1 |
| Chambers, EL; Downing, SJ; Leese, HJ; Maguiness, SD; Watson, A | 1 |
| Omann, GM; Rengan, R | 1 |
| Casale, TB; Erger, RA; Rozell, MD | 1 |
| Borregaard, N; Bratt, T; Ohlson, S | 1 |
| Binder, R; Kirschfink, M; Kress, A | 1 |
| Byrum, RS; Goulet, JL; Griffiths, RJ; Koller, BH; Snouwaert, JN | 1 |
| Fox-Robichaud, A; Kubes, P; Payne, D | 1 |
| Burgermeister, E; Heinrich, PC; Küster, A; Pessara, U; Scheuer, WV; Tibes, U | 1 |
| Atilla, G; Coker, I; Emingil, G; Hüseyinov, A | 1 |
| Bardhan, KD; Brown, NJ; Jacob, S; Kalia, N; Reed, MW | 1 |
| Boichot, E; Braquet, P; Carre, C; Guinot, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Adams, J; Deitch, EA; Fekete, Z; Garced, M; Hauser, CJ; Livingston, DH | 1 |
| Denizot, Y; Godard, A; Praloran, V; Raher, S; Trimoreau, F | 1 |
| Bieniek, E; Grandel, U; Grimminger, F; Kiss, L; Mayer, K; Rose, F; Seeger, W; Sibelius, U | 1 |
| Dohi, T; Kitayama, S; Kurihara, H; Mizuno, N; Morita, K; Shibata, K; Shinohara, H; Yoshino, H | 1 |
| Benfield, T; Cowan, MJ; Logun, C; Shelhamer, JH; Tavakoli, S | 1 |
| Kindzelskii, AL; Petty, HR | 1 |
| Bizer, C; Schapowal, A; Simon, HU; Thomet, OA; Wiesmann, UN | 1 |
| Ibe, BO; Raj, JU | 1 |
| Banville, J; Brassil, PJ; Burke, JR; Davern, LB; Gregor, KR; Johnson, G; Remillard, R; Russell, JW; Stanley, PL; Tramposch, KM; Tredup, JA; Witmer, MR | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Hanson, AJ; Quinn, MT; Siemsen, DW; Swain, SD | 1 |
| Haynes, J; Obiako, B | 1 |
| Chao, YY; Chen, IS; Chen, JJ; Chen, WC; Cheng, JS; Chou, KJ; Jan, CR; Ko, YC; Lee, KC; Liu, CP; Lo, YK; Su, W | 1 |
| Costa, CH; Cunha, FQ; Ferreira, SH; Oliveira, SH | 1 |
| Barcelos, L; Klein, A; Machado, FS; Santana, GC; Silva, JS; Talvani, A; Teixeira, MM | 1 |
| Fonteh, AN | 1 |
| Grandel, U; Grimminger, F; Hattar, K; Hoffmann, S; Mayer, K; Schenkel, A; Seeger, W; Sibelius, U | 1 |
| Akisu, M; Baka, M; Huseyinov, A; Kultursay, N; Yalaz, M | 1 |
| Benjamim, CF; Cunha, Fde Q; Ferreira, SH; Rios-Santos, F; Zavery, D | 1 |
| Casillan, AJ; Gonzalez, NC; Johnson, JS; Steiner, DR; Wood, JG | 1 |
| Hara, M; Ishida, S; Korthuis, RJ; Sakata, T; Shigematsu, S; Takahashi, N; Yoshimatsu, H | 1 |
| Kamei, C; Ogawa, M; Sugimoto, Y; Tai, N | 1 |
| Barcelos, LS; Ishii, S; Romanha, AJ; Santana, G; Shimizu, T; Silva, JS; Soares, MB; Talvani, A; Teixeira, MM | 1 |
| Ando, K; Mano, T; Miyamoto, K; Nakao, K; Okumura, T; Okumura, Y; Sakakibara, M; Stevens, RW; Tamura, T | 1 |
| Acuña, A; Chung, KF; Gabrijelcic, J; Paternò, A; Profita, M; Rodríguez-Roisin, R; Vignola, AM | 1 |
| Beck-Speier, I; Dayal, N; Denzlinger, C; Haberl, C; Heyder, J; Maier, KL; Ziesenis, A | 1 |
| Croxtall, JD; Gilroy, DW; Newson, J; Sawmynaden, P; Willoughby, DA | 1 |
| Alteraifi, AM; Chodniewicz, D; Zhelev, DV | 1 |
| Brown, GE; Cherepanov, V; Degousee, N; Downey, GP; Gelb, MH; Ghomashchi, F; Glogauer, M; Grinstein, S; Harkin, DW; Kelvin, D; Koh, A; Lindsay, TF; Nallan, L; Plumb, J; Rubin, BB; Sadilek, M; Smart, BP; Stefanski, E; Sun, C; Vachon, E; Yaffe, MB | 1 |
| Atilla, G; Başkesen, A; Berdeli, AH; Buduneli, E; Buduneli, N; Türkoğlu, O; Vardar, S | 1 |
| Atilla, G; Başkesen, A; Baylas, H; Berdeli, AH; Buduneli, E; Türkoğlu, O; Vardar, S | 1 |
| Fulkerson, PC; Rothenberg, ME; Williams, DA; Zhu, H; Zimmermann, N | 1 |
| Atilla, G; Baylas, H; Berdeli, AH; Buduneli, E; Buduneli, N; Vardar, S | 1 |
| Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ | 1 |
| Hagiwara, K; Kanazawa, M; Kikuchi, I; Kikuchi, S; Kobayashi, T; Nagata, M; Sakamoto, Y | 1 |
| Desaulniers, P; Gilbert, C; Marois, S; Naccache, PH; Paré, G; Popa-Nita, O | 1 |
| Borgeat, M; Borgeat, P; Hattermann, K; Leclerc, P; Picard, S; Pouliot, M | 1 |
| Dangerfield, J; Nourshargh, S; Voisin, MB; Wang, S; Young, RE | 1 |
| Clandinin, MT; Ma, DW; Park, EJ; Ramanujam, K; Suh, M; Thomson, AB; Thomson, B | 1 |
| Anderson, R; Steel, HC; Theron, AJ; Tintinger, GR | 2 |
| Eckert, RE; Jones, SL | 1 |
| Bélanger, C; Borgeat, P; Elimam, H; Lefebvre, J; Marleau, S | 1 |
| Anderson, R; Steel, HC; Tintinger, GR | 1 |
| Blikslager, AT; Cook, VL; Jones, SL; Neuder, LE | 1 |
| Borgeat, P; Flamand, N; Lefebvre, JS; Lévesque, T; Marleau, S; Milot, V; Picard, S | 1 |
| Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T | 1 |
| Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
| Ahluwalia, J; Salmon, MD | 1 |
| Brooks, AC; Cunningham, FM; Rickards, KJ | 1 |
| Greiner, C; Hörnig, C; Pergola, C; Rossi, A; Sautebin, L; Schubert-Zsilavecz, M; Steinhilber, D; Werz, O; Zettl, H | 1 |
| Fischlein, T; Förch, S; Juchem, G; Knott, M; Kreuzer, E; Laufer, S; Nees, S; Reichart, B; Senftl, A; Weiss, DR | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
| Degawa-Yamauchi, M; Kanegasaki, S; Kuribayashi, F; Tsuchiya, T; Yamauchi, A | 1 |
| Bessi, VL; Bitencourt, CS; Borgeat, P; Faccioli, LH; Hamdan, L; Huynh, DN; Lefebvre, JS; Lévesque, T; Marleau, S; Ménard, L; Sohouhenou, F | 1 |
| Bae, YS; Im, SY; Kim, HK; Lee, HK; Song, CH | 1 |
29 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene b4
| Article | Year |
|---|---|
Leukotriene B4 and platelet-activating factor in human skin.
Topics: Dermatitis; Humans; Leukotriene B4; Platelet Activating Factor; Psoriasis; Skin Physiological Phenomena | 1992 |
[Mediators of inflammation and hemorrhagic rectocolitis].
Topics: Arachidonic Acids; Colitis, Ulcerative; Dinoprost; Dinoprostone; Eicosanoids; Gastrointestinal Motility; Humans; Leukotriene B4; Platelet Activating Factor | 1991 |
Neutrophil chemotactic factors.
Topics: Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; Inflammation; Leukotriene B4; Neuropeptides; Neutrophils; Platelet Activating Factor; Platelet Factor 4 | 1991 |
Molecular mechanisms of leukocyte activation by chemoattractants.
Topics: Animals; Chemotactic Factors; GTP-Binding Proteins; Humans; Leukocytes; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor | 1991 |
LTB4 and PAF in the cytokine network.
Topics: Animals; Cytokines; Humans; Inflammation; Interferon-gamma; Interleukin-1; Interleukin-6; Leukotriene B4; Macrophages; Models, Biological; Monocytes; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1991 |
Growth factors, lipid mediators and effector cells.
Topics: Animals; Cytokines; Hematopoietic Cell Growth Factors; Humans; Leukocytes; Leukotriene B4; Lipids; Platelet Activating Factor | 1990 |
Mediator release from human basophils and mast cells from lung and intestinal mucosa.
Topics: Antibodies, Anti-Idiotypic; Arachidonic Acid; Arachidonic Acids; Basophils; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Intestinal Mucosa; Leukotriene B4; Lipoxygenase; Lung; Mast Cells; Peptide Hydrolases; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins D; SRS-A | 1985 |
Inflammatory mediators of asthma.
Topics: Asthma; Chemotactic Factors; Histamine Release; Humans; Hypersensitivity, Immediate; Leukotriene B4; Peptides; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Lipid mediators of anaphylaxis and increased airways reactivity.
Topics: Anaphylaxis; Arachidonic Acids; Asthma; Bronchitis; Histamine; Humans; Leukotriene B4; Lipid Metabolism; Platelet Activating Factor; SRS-A | 1987 |
[Prostaglandins and related compounds].
Topics: Animals; Arachidonic Acids; Exotoxins; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Platelet Activating Factor; Prostaglandins; Thromboxanes | 1988 |
Alteration in microvascular permeability induced by products released during inflammation.
Topics: Animals; Bradykinin; Capillary Permeability; Complement C5; Complement C5a; Histamine; Humans; Inflammation; Leukotriene B4; Lung; Neuropeptides; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
The role of leukotrienes in allergen-induced late responses in allergic sheep.
Topics: Allergens; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchial Spasm; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene B4; Models, Biological; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sheep; SRS-A | 1988 |
Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions.
Topics: Animals; Arachidonic Acids; Dinoprostone; Diterpenes; Eicosanoic Acids; Enzyme Activation; Ginkgolides; Guinea Pigs; Hypersensitivity; Inflammation; Lactones; Leukotriene B4; Lung; Muscle Contraction; Phospholipases; Phospholipases A; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2 | 1987 |
Prostaglandins, leukotrienes, phospholipase, platelet activating factor, and cytokines: an integrated approach to inflammation of human skin.
Topics: Annexins; Arachidonic Acid; Arachidonic Acids; Dermatitis; Glycoproteins; Humans; Interleukin-1; Leukotriene B4; Lipoxygenase; Phospholipases; Platelet Activating Factor; Prostaglandins; Psoriasis | 1988 |
[Current trends in the development of the science of coagulation abroad].
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Blood Coagulation; Blood Coagulation Factors; Blood Coagulation Tests; Blood Proteins; Calmodulin; Factor VIII; Fibrinolysis; Fibrinolytic Agents; Fibronectins; Genetic Engineering; Hematology; Humans; Immunologic Techniques; Leukotriene B4; Platelet Activating Factor; Platelet-Derived Growth Factor; Research Design; SRS-A | 1985 |
Immunopharmacology of anaphylatoxin-induced bronchoconstrictor responses.
Topics: Anaphylatoxins; Animals; Bronchi; Bronchial Spasm; Complement Activation; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Inflammation; Leukotriene B4; Lung; Mice; Muscle Contraction; Peptides; Platelet Activating Factor; SRS-A | 1986 |
Phospholipid metabolism and stimulus-response coupling.
Topics: Calcium; Cells; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Models, Biological; Phospholipids; Platelet Activating Factor; Protein Kinase C | 1987 |
Lipid-derived and other chemical mediators of inflammation in the lung.
Topics: Anaphylatoxins; Arachidonic Acid; Arachidonic Acids; Asthma; Eicosanoic Acids; Fatty Acids; Humans; Leukocytes; Leukotriene B4; Lung; Macrophage Activation; Mucus; Platelet Activating Factor; Pneumonia; Prostaglandin-Endoperoxide Synthases; Respiratory Distress Syndrome; SRS-A | 1987 |
Prostaglandins, leukotrienes, and platelet-activating factor in shock.
Topics: Animals; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Shock; SRS-A; Thromboxane A2 | 1987 |
Lipid mediators produced through the lipoxygenase pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Interleukin-2; Leukotriene B4; Lipid Metabolism; Lipoxygenase; Platelet Activating Factor; SRS-A; T-Lymphocytes | 1987 |
Mediators of anaphylaxis and inflammation.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Autacoids; Chemical Phenomena; Chemistry; Chemotactic Factors; Chemotactic Factors, Eosinophil; Histamine; Humans; Hydrolases; Inflammation; Leukocytes; Leukotriene B4; Mast Cells; Platelet Activating Factor; Prostaglandins; Serotonin; SRS-A; Structure-Activity Relationship; Thromboxanes; Vasoactive Intestinal Peptide | 1982 |
Structure and function of the chemical mediators of mast cells.
Topics: Animals; Arachidonic Acids; Arylsulfatases; Biogenic Amines; Chemotactic Factors; Cytoplasmic Granules; Endopeptidases; Glycoside Hydrolases; Humans; Leukotriene B4; Mast Cells; Neprilysin; Peroxidases; Platelet Activating Factor; Proteoglycans; SRS-A; Superoxide Dismutase | 1984 |
Tolfenamic acid and leukotriene synthesis inhibition.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Degranulation; Chemotaxis, Leukocyte; Humans; Leukotriene B4; Neutrophils; ortho-Aminobenzoates; Platelet Activating Factor | 1994 |
Effect of bacterial products on neutrophil chemotaxis.
Topics: Animals; Bacterial Toxins; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Filtration; Guinea Pigs; Humans; Indicators and Reagents; Leukotriene B4; Lipopolysaccharides; Neutrophils; Platelet Activating Factor; Sepharose | 1994 |
Impaired activation of phospholipase D in polycythaemia vera-implications for the pathogenesis of the disease?
Topics: Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Phospholipase D; Platelet Activating Factor; Polycythemia Vera; Tetradecanoylphorbol Acetate | 1995 |
Neutrophils and myocardial reperfusion injury.
Topics: Animals; Antibodies; Cell Adhesion Molecules; Complement C5a; Disease Models, Animal; Free Radicals; Humans; Interleukin-8; Leukotriene B4; Myocardial Reperfusion Injury; Myocardial Stunning; Neutrophils; Platelet Activating Factor | 1996 |
Mechanisms of cell signaling in immune-mediated inflammation.
Topics: Anaphylatoxins; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chemokines; Chemotactic Factors; Dinoprostone; GTP-Binding Proteins; Immunoglobulin G; Inflammation; Leukocytes; Leukotriene B4; Leukotrienes; Lipids; Mice; Models, Biological; NF-kappa B; Phagocytes; Phospholipases A; Platelet Activating Factor; Signal Transduction; Thromboxane A2 | 1998 |
Adenosine. An endogenous inhibitor of arachidonic acid release and leukotriene biosynthesis in human neutrophils.
Topics: Adenosine; Animals; Arachidonic Acid; Humans; Leukotriene B4; Neutrophils; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Theophylline | 1999 |
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions.
Topics: Anticholesteremic Agents; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Leukotriene B4; Lipoproteins, LDL; Monocytes; Platelet Activating Factor | 1999 |
6 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene b4
| Article | Year |
|---|---|
Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Blood Platelets; Bronchodilator Agents; Budesonide; Catecholamines; Drug Synergism; Female; Histamine; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Platelet Count; Pregnenediones; Reference Values; Thromboxane B2 | 1992 |
Biochemical perturbations of BW 91Y (3-deazaadenosine) on human neutrophil chemotactic potential and lipid metabolism.
Topics: Arachidonic Acids; Arthritis, Rheumatoid; Calcimycin; Chemotaxis, Leukocyte; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Leukotriene B4; Lipid Metabolism; Lipids; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Platelet Activating Factor; Tubercidin | 1991 |
Long-term effect of nonsteroidal anti-inflammatory drugs on the production of cytokines and other inflammatory mediators by blood cells of patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Diclofenac; Dinoprostone; Double-Blind Method; Female; Humans; Interleukin-1; Interleukin-6; Knee Joint; Leukotriene B4; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osteoarthritis; Platelet Activating Factor; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 1994 |
The effect of nizatidine on duodenal ulcer healing and on mucosal inflammatory mediators.
Topics: Adult; Aged; Dinoprostone; Double-Blind Method; Duodenal Ulcer; Female; Gastric Mucosa; Gastroscopy; Humans; Leukotriene B4; Leukotriene C4; Male; Middle Aged; Nizatidine; Platelet Activating Factor; Radioimmunoassay; Risk Factors | 1994 |
Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Dinoprostone; Ketoprofen; Leukotriene B4; Male; Phenylbutazone; Placebos; Platelet Activating Factor; Pneumonia; Respiration; Thromboxane B2 | 1999 |
Neutrophil airway influx by platelet-activating factor in asthma: role of adhesion molecules and LTB4 expression.
Topics: Adult; Asthma; Cross-Over Studies; Double-Blind Method; Female; Humans; Inflammation Mediators; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Sputum | 2003 |
441 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and leukotriene b4
| Article | Year |
|---|---|
Neutrophil chemotactic factors promote leukocytosis. A common mechanism for cellular recruitment from bone marrow.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chemotactic Factors; Complement C5a; Dactinomycin; Interleukin-8; Leukocytosis; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyrazoles; Rabbits; Receptors, Formyl Peptide; Receptors, Immunologic | 1992 |
Colchicine and methotrexate reduce leukocyte adherence and emigration in rat mesenteric venules.
Topics: Animals; Cell Adhesion; Cell Migration Inhibition; Colchicine; Flow Cytometry; Humans; Leukocytes; Leukotriene B4; Male; Mesentery; Methotrexate; Microscopy; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains; Venules; Video Recording | 1992 |
Selective eosinophil leukocyte recruitment by transendothelial migration and not by leukocyte-endothelial cell adhesion.
Topics: Amitrole; Cell Adhesion; Cell Movement; Cytokines; Endothelium, Vascular; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Interleukin-1; Leukotriene B4; Lipopolysaccharides; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidases; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1992 |
Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects.
Topics: Asthma; Chemotaxis, Leukocyte; Eosinophilia; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-5; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rhinitis | 1992 |
A rapid microtiter plate method for the detection of lysozyme release from human neutrophils.
Topics: Amino Acid Sequence; Benzophenones; Cell Separation; Complement C5a; Humans; Leukotriene B4; Methods; Molecular Sequence Data; Muramidase; Neutrophils; Oligopeptides; Platelet Activating Factor; Protamines | 1992 |
Formation of LTB4 by fMLP-stimulated alveolar macrophages accounts for eosinophil migration in vitro.
Topics: Animals; Benzeneacetamides; Cell Movement; Chemotactic Factors, Eosinophil; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Hydroxamic Acids; Indomethacin; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Sensitivity and Specificity; Stimulation, Chemical | 1992 |
Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5-lipoxygenase products.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Humans; Intracellular Fluid; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1992 |
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Splanchnic Circulation; Venules | 1992 |
Degree of neutrophil chemotaxis is dependent upon the chemoattractant and barrier.
Topics: Animals; Cell Line; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Dogs; Endothelium, Vascular; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1992 |
A kinetic study of immune mediators in the lungs of mice infected with influenza A virus.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Influenza A virus; Leukotriene B4; Mice; Orthomyxoviridae Infections; Platelet Activating Factor; Time Factors | 1992 |
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Bronchoalveolar Lavage Fluid; Dinoprostone; Diterpenes; Econazole; Ginkgolides; Hemoglobins; Hemorrhage; Indomethacin; Lactones; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; Thromboxanes; Triazoles | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
Alpha-MSH peptides inhibit acute inflammation induced in mice by rIL-1 beta, rIL-6, rTNF-alpha and endogenous pyrogen but not that caused by LTB4, PAF and rIL-8.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Interleukin-1; Interleukin-6; Interleukin-8; Leukotriene B4; Mice; Peptide Fragments; Platelet Activating Factor; Pyrogens; Rabbits; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Chemoattractants provoke monocyte adhesion to human mesangial cells and mesangial cell injury.
Topics: Antibodies, Monoclonal; Cell Adhesion; Cells, Cultured; Complement C5a; Cytokines; Glomerular Mesangium; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Integrins; Leukotriene B4; Monocytes; Platelet Activating Factor | 1992 |
Effects of nedocromil sodium and WEB 2086 on chemoattractant-stimulated neutrophil migration through cellular and noncellular barriers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azepines; Cells, Cultured; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; Triazoles | 1992 |
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction.
Topics: Animals; Arthus Reaction; Azepines; Complement System Proteins; Edema; Isoquinolines; Leukotriene B4; Platelet Activating Factor; Rabbits; Radioimmunoassay; Receptors, Complement; Tetrazoles; Triazoles; Zymosan | 1992 |
Arachidonic acid release and platelet-activating factor formation by staurosporine in human neutrophils challenged with n-formyl peptide.
Topics: Alkaloids; Arachidonic Acid; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protein Kinase C; Staurosporine | 1992 |
Platelet activating factor amplifies human neutrophil adherence to bovine endothelial cells: evidence for a lipoxygenase dependent mechanism.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cattle; Cell Adhesion; Cell Communication; Cells, Cultured; Endothelium, Vascular; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Sequence Data; Neutrophils; Platelet Activating Factor; SRS-A | 1992 |
Platelet-activating factor enhances interleukin-6 production by alveolar macrophages.
Topics: Animals; Cells, Cultured; Diterpenes; Ginkgolides; Indoles; Interleukin-6; Lactones; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Rats; Rats, Wistar | 1992 |
Platelet activating factor is a mediator of equine neutrophil and eosinophil migration in vitro.
Topics: Animals; Cells, Cultured; Chemotaxis, Leukocyte; Eosinophils; Horses; Leukotriene B4; Neutrophils; Platelet Activating Factor | 1992 |
Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules.
Topics: Cytoplasmic Granules; Enzyme-Linked Immunosorbent Assay; Gelatinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactoferrin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pepsin A; Platelet Activating Factor; Protein Binding; Subcellular Fractions; Vitamin B 12; Zymosan | 1992 |
Plasma levels of the lipid mediators, leukotriene B4 and lyso platelet-activating factor, in intraoperative salvaged blood.
Topics: Blood Platelets; Blood Transfusion, Autologous; Humans; Intraoperative Period; Leukocytes; Leukotriene B4; Lipids; Platelet Activating Factor; Reference Values | 1992 |
Inhibition of calcimycin-induced stimulation of cytosolic calcium in human PMN by a LTB4 receptor antagonist.
Topics: Arachidonate 5-Lipoxygenase; Benzopyrans; Calcimycin; Calcium; Cytosol; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Receptors, Immunologic; Receptors, Leukotriene B4 | 1992 |
Regulation of leukotriene biosynthesis in human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Chromatography, High Pressure Liquid; Egtazic Acid; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1992 |
Effects of cytokines on human basophil chemotaxis.
Topics: Basophils; Chemotaxis; Complement C5a; Cytokines; Humans; Leukotriene B4; Platelet Activating Factor; Recombinant Proteins | 1992 |
Effects of dauricine and anisodamine on LTs and PAF induced DNA synthesis in bovine anterior cerebral arterial smooth muscle cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Cattle; Cells, Cultured; Cerebral Arteries; DNA; Isoquinolines; Leukotriene B4; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Solanaceous Alkaloids; SRS-A; Tetrahydroisoquinolines; Vasodilator Agents | 1992 |
Leukotriene B4 mediates shear rate-dependent leukocyte adhesion in mesenteric venules.
Topics: Animals; Antigens, CD; Azepines; Benzopyrans; Cats; CD18 Antigens; Endothelium, Vascular; Indoles; Leukocytes; Leukotriene B4; Mesenteric Veins; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Triazoles; Venules | 1992 |
Phalloidin prevents leukocyte emigration induced by proinflammatory stimuli in rat mesentery.
Topics: Animals; Antigens, CD; CD11 Antigens; CD18 Antigens; Chemotaxis, Leukocyte; Flow Cytometry; Leukocytes; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Phalloidine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Venules | 1992 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles | 1992 |
Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules.
Topics: Animals; Capillaries; Cell Adhesion; Cell Movement; Cyclosporine; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tacrolimus; Venules | 1992 |
Neuropeptides modulate human eosinophil chemotaxis.
Topics: Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Neuropeptides; Peptide Fragments; Platelet Activating Factor; Protease Inhibitors; Receptors, Calcitonin; Receptors, Cell Surface; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1992 |
Receptor-operated activation of polymorphonuclear leukocytes: different effects of NAP-1/IL-8 and fMet-Leu-Phe or C5a.
Topics: Arachidonate 5-Lipoxygenase; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides | 1991 |
[Effects of anti-asthmatic drugs on human eosinophil chemotaxis].
Topics: Aminophylline; Asthma; Cells, Cultured; Chemotaxis, Leukocyte; Dexamethasone; Eosinophils; Humans; Isoproterenol; Leukotriene B4; Platelet Activating Factor | 1991 |
Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3.
Topics: Chemotaxis, Leukocyte; Complement C5a; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor | 1991 |
The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.
Topics: Albumins; Animals; Cell Movement; Complement C5a; Dermatitis, Atopic; Eosinophils; Female; Guinea Pigs; Indium Radioisotopes; Leukotriene B4; Platelet Activating Factor; Recombinant Proteins; Skin; Zymosan | 1991 |
LTB4, a potent chemotactic factor for purified guinea-pig eosinophils: interference of PAF-acether antagonists.
Topics: Animals; Azepines; Chemotaxis, Leukocyte; Diterpenes; Eosinophils; Female; Ginkgolides; Guinea Pigs; In Vitro Techniques; Lactones; Leukotriene B4; Male; Platelet Activating Factor; Triazoles | 1991 |
Lipid mediators of tumor necrosis factor-alpha-induced uveitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Eicosanoids; Eye Proteins; Indomethacin; Leukocyte Count; Leukotriene B4; Male; Naproxen; Platelet Activating Factor; Prostaglandins E; Quinolinium Compounds; Rabbits; Recombinant Proteins; Tumor Necrosis Factor-alpha; Uveitis, Anterior; Vitreous Body | 1991 |
Enhancement of pulmonary natural killer cell activity by platelet activating factor. Mechanisms of activation involving Ca2+, protein kinase C, and lipooxygenase products.
Topics: Animals; Arachidonate 5-Lipoxygenase; Calcium; Cytotoxicity, Immunologic; Killer Cells, Natural; Leukotriene B4; Lung; Lymphocytes; Male; Platelet Activating Factor; Protein Kinase C; Rats; Rats, Inbred Strains | 1991 |
Roles of Ca2+ in human neutrophil responses to receptor agonists.
Topics: Calcium; Cell Degranulation; Glucuronidase; Humans; In Vitro Techniques; Leukotriene B4; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Leukotriene B4; Signal Transduction; Superoxides; Temperature; Time Factors | 1991 |
Mechanisms of the coronary vascular effects of platelet-activating factor in the rat perfused heart.
Topics: Animals; Blood Pressure; Coronary Circulation; Diterpenes; Ginkgolides; Heart; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene Antagonists; Leukotriene B4; Perfusion; Phenylbutyrates; Piperazines; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A | 1991 |
Modulation of leukotriene B4 and platelet-activating factor binding to neutrophils.
Topics: Alkaloids; Calcium; Cell Membrane; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
The effect of lipoproteins on the release of some eicosanoids by stimulated human leukocytes. A possible role in atherogenesis.
Topics: Arachidonic Acid; Calcimycin; Dextran Sulfate; Dinoprostone; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Lipoproteins, LDL; Platelet Activating Factor | 1991 |
Thrombin-activated platelets promote leukotriene B4 synthesis in polymorphonuclear leucocytes stimulated by physiological agonists.
Topics: Arachidonate 12-Lipoxygenase; Arachidonic Acid; Blood Platelets; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Activation; Thrombin | 1991 |
Suppression of cytoskeletal rearrangement in activated human neutrophils by botulinum C2 toxin. Impact on cellular signal transduction.
Topics: Actins; Aminoquinolines; Botulinum Toxins; Calcium; Cytoskeleton; Diglycerides; Fluorescent Dyes; Humans; Inositol Phosphates; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Platelet Activating Factor; Polymers; Signal Transduction; Superoxides | 1991 |
Activation of guinea pig eosinophils by human recombinant IL-5. Selective priming to platelet-activating factor-acether and interference of its antagonists.
Topics: Animals; Calcium; Cell Movement; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Humans; Interleukin-5; Lactones; Leukotriene B4; Lipopolysaccharides; Platelet Activating Factor; Recombinant Proteins; Superoxides | 1991 |
Inhibition of cytoskeletal rearrangement by botulinum C2 toxin amplifies ligand-evoked lipid mediator generation in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Botulinum Toxins; Chemotactic Factors; Chemotaxis, Leukocyte; Cytoskeleton; Eicosanoids; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phosphatidylinositols; Platelet Activating Factor | 1991 |
Platelet-activating factor impairs mucociliary transport and increases plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Aspirin; Bronchi; Female; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Mucociliary Clearance; Platelet Activating Factor; Platelet Aggregation; Respiratory Mechanics | 1991 |
Tumor necrosis factor-alpha regulates expression of receptors for formyl-methionyl-leucyl-phenylalanine, leukotriene B4, and platelet-activating factor. Dissociation from priming in human polymorphonuclear neutrophils.
Topics: Cell Degranulation; Humans; In Vitro Techniques; Leukotriene B4; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Leukotriene B4; Tumor Necrosis Factor-alpha; Up-Regulation | 1991 |
Granulocyte chemotaxis in the canine trachea: inhibition by lipid mediator antagonists and systemic inhibitors.
Topics: Animals; Chemotaxis, Leukocyte; Dogs; Female; Granulocytes; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipid Peroxidation; Lipids; Male; Methylprednisolone; Platelet Activating Factor; Trachea | 1991 |
Differential effects of propranolol on responses to receptor-dependent and receptor-independent stimuli in human neutrophils.
Topics: Calcium; Humans; In Vitro Techniques; Ionomycin; Isomerism; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Platelet Activating Factor; Propranolol; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
PAF-mediated platelet adhesion to endothelial cells induced by FMLP-stimulated leukocytes.
Topics: Azepines; Endothelium, Vascular; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Adhesiveness; Triazoles; Umbilical Veins | 1991 |
Changes in inositol 1,4,5-trisphosphate mass in agonist-stimulated human neutrophils.
Topics: Calcium Channels; Cholera Toxin; Cytochalasin B; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Respiratory Burst; Stimulation, Chemical; Virulence Factors, Bordetella | 1991 |
Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Dinoprostone; Disease Models, Animal; Histamine; Interleukin-1; Leukotriene B4; Peroxidase; Platelet Activating Factor; Saguinus | 1991 |
PAF and LTB4 biosynthesis in the human neutrophil: effects of putative inhibitors of phospholipase A2 and specific inhibitors of 5-lipoxygenase.
Topics: Acetyltransferases; Calcimycin; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1991 |
Transcellular metabolism of arachidonic acid in platelets and polymorphonuclear leukocytes activated by physiological agonists: enhancement of leukotriene B4 synthesis.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Activation; Thrombin | 1991 |
The identification of PAF-release-enhancing activity in culture supernatant of mononuclear cells from asthmatics. Correlation between lymphocyte responses and immediate type hypersensitivity.
Topics: Asthma; Cells, Cultured; Culture Media; Humans; Hypersensitivity, Immediate; Leukocytes, Mononuclear; Leukotriene B4; Lymphocyte Activation; Neutrophils; Platelet Activating Factor; Pollen | 1991 |
Synergistic effect of thromboxane A2 and N-formylmethionylleucylphenylalanine on platelet-activating factor synthesis in human polymorphonuclear neutrophils.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetyl-CoA C-Acetyltransferase; Binding Sites; Bridged Bicyclo Compounds; Drug Synergism; Fatty Acids, Monounsaturated; Humans; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Thromboxane A2 | 1991 |
Effect of dietary alpha-linolenate on platelet-activating factor production in rat peritoneal polymorphonuclear leukocytes.
Topics: alpha-Linolenic Acid; Animals; Calcimycin; Dietary Fats, Unsaturated; Inflammation; Leukotriene B4; Linolenic Acids; Male; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
The effect of cetirizine on antigen-dependent leucopenia in the guinea-pig.
Topics: Animals; Benzeneacetamides; Benzhydryl Compounds; Blood Platelets; Cetirizine; Female; Guinea Pigs; Histamine H1 Antagonists; Hydroxamic Acids; Hydroxyzine; In Vitro Techniques; Leukocyte Count; Leukopenia; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrilamine; Terfenadine | 1991 |
Leukocyte-induced vascular protein leakage in cat mesentery.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Capillary Permeability; Cats; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Movement; Leukotriene B4; Mesentery; Microcirculation; Neutrophils; Platelet Activating Factor; Proteins | 1991 |
Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Acyltransferases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Coenzyme A Ligases; Fatty Acids; Humans; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Theophylline | 1990 |
Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer.
Topics: Animals; Azepines; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Hydroxyzine; In Vitro Techniques; Ketotifen; Leukotriene B4; Male; Mast Cells; Pepsin A; Peptide Fragments; Platelet Activating Factor; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; SRS-A; Substance P; Triazoles | 1991 |
Site of anti-inflammatory action of dexamethasone in rabbit skin.
Topics: Animals; Bradykinin; Dactinomycin; Dermatitis, Contact; Dexamethasone; Dinoprostone; Female; Histamine; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Biosynthesis; Rabbits; RNA; Skin; Zymosan | 1991 |
The effects of cytokines, platelet activating factor, and arachidonate metabolites on C3b receptor (CR1, CD35) expression and phagocytosis by neutrophils.
Topics: Antigens, CD; Arachidonic Acids; Complement C3b; Cytokines; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Receptors, Complement; Receptors, Complement 3b; Recombinant Proteins; Tumor Necrosis Factor-alpha; Up-Regulation | 1990 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Granulocyte-macrophage colony-stimulating factor increases the synthesis of leukotriene B4 by human neutrophils in response to platelet-activating factor. Enhancement of both arachidonic acid availability and 5-lipoxygenase activation.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Diterpenes; Enzyme Activation; Ginkgolides; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactones; Leukotriene B4; Neutrophils; Platelet Activating Factor | 1991 |
Tumor necrosis factor-alpha priming of phospholipase A2 activation in human neutrophils. An alternative mechanism of priming.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cytochalasin B; Diglycerides; Enzyme Activation; Humans; Leukotriene B4; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1991 |
Recombinant human interleukin-8 is a potent activator of canine neutrophil aggregation, migration, and leukotriene B4 biosynthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Aggregation; Chemotaxis, Leukocyte; Cycloheximide; Dogs; Humans; Injections, Intradermal; Interleukin-1; Interleukin-8; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Skin | 1991 |
Regulation of the superoxide-forming NADPH oxidase of human neutrophils is not altered in essential hypertension.
Topics: Adult; Female; Humans; Hypertension; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Signal Transduction; Superoxides | 1991 |
Involvement of leukotriene B4 and platelet-activating factor in cytokine priming of human polymorphonuclear leucocytes.
Topics: Cells, Cultured; Cytokines; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Superoxides | 1991 |
Phospholipase D activation by platelet-activating factor, leukotriene B4, and formyl-methionyl-leucyl-phenylalanine in rabbit neutrophils. Phospholipase D activation is involved in enzyme release.
Topics: Animals; Cell Degranulation; Diglycerides; Enzyme Activation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Rabbits | 1991 |
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Necrosis; Phospholipid Ethers; Platelet Activating Factor; Shock, Septic | 1990 |
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Second Messenger Systems; Tetrazoles; Thiazoles; Thienopyridines; Triazoles | 1990 |
Production of superoxide anion and hydrogen peroxide by human neutrophilic granulocytes during chemotactic migration towards f-Met-Leu-Phe, C5a, leukotriene B4, monocyte-derived chemotaxin/IL-8 and platelet-activating factor.
Topics: Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; Hydrogen Peroxide; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides | 1990 |
Enhancement of platelet-activating factor-induced leukotriene synthesis in neutrophils by granulocyte-macrophage colony-stimulating factor (GM-CSF): studies on the mechanism of action of GM-CSF.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Leukotrienes; Lipid Peroxides; Neutrophils; Platelet Activating Factor | 1990 |
Enhancement of the expression of eosinophil IgE receptor (Fc epsilon R2) and its function by platelet-activating factor.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cytotoxicity, Immunologic; Eosinophils; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene B4; Platelet Activating Factor; Receptors, Fc; Receptors, IgE; Schistosoma mansoni; SRS-A | 1990 |
Rapid adhesive responses of endothelial cells and of neutrophils induced by leukotriene B4 are mediated by leucocytic adhesion protein CD18.
Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plastics; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Thrombin | 1990 |
Leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils.
Topics: Cell Adhesion; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1990 |
The adhesiveness of monocytic U937 cells is stimulated by pro-inflammatory agents and inhibited by adenosine 3':5'-cyclic monophosphate.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Alprostadil; Bucladesine; Calcitriol; Cell Adhesion; Cell Differentiation; Cell Line; Cyclic AMP; Diglycerides; Humans; Kinetics; Leukotriene B4; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Tretinoin | 1990 |
Identification of a novel and highly potent eosinophil chemotactic lipid in human eosinophils treated with arachidonic acid.
Topics: Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Eosinophils; Glutathione; Humans; In Vitro Techniques; Leukotriene B4; Lipids; Magnesium; Platelet Activating Factor; Structure-Activity Relationship | 1990 |
Role of spermatozoal platelet-activating factor in fertilization.
Topics: Animals; Arachidonic Acids; Azepines; Chromatography, High Pressure Liquid; Female; Fertilization; Fertilization in Vitro; Humans; Leukotriene B4; Lipoxygenase; Male; Mice; Platelet Activating Factor; Pregnancy; Prostaglandins F; Sperm Motility; Spermatozoa; Thromboxane B2; Triazines; Triazoles | 1990 |
Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents.
Topics: Blood Platelets; Calcium; Cell Aggregation; Cytoplasm; Humans; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Time Factors | 1990 |
GM-CSF: receptor structure and transmembrane signaling.
Topics: Cell Membrane; Colony-Stimulating Factors; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Platelet Activating Factor; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Sepharose; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Leukotriene B4 potentiates colonic ulceration in the rat.
Topics: Administration, Rectal; Animals; Colitis; Drug Synergism; Ethanol; Leukotriene B4; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Platelet Activating Factor; Rats; Rats, Inbred Strains; Ulcer | 1990 |
Role of platelet-activating factor and eicosanoids during endotoxin-induced lung injury in pigs.
Topics: Animals; Body Water; Calcimycin; Capillary Permeability; Chromatography, High Pressure Liquid; Eicosanoids; Endotoxins; Escherichia coli; Heart; Leukotriene B4; Lung; Lung Diseases; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Quinolines; Swine | 1990 |
ATP and guanine nucleotide dependence of neutrophil activation. Evidence for the involvement of two distinct GTP-binding proteins.
Topics: Adenosine Triphosphate; Alkaloids; Arachidonic Acid; Arachidonic Acids; Cell Membrane Permeability; GTP-Binding Proteins; Guanine Nucleotides; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Models, Biological; Neutrophils; Oxygen Consumption; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Virulence Factors, Bordetella | 1990 |
Studies on the mechanism of platelet-activating factor production in GM-CSF primed neutrophils: involvement of protein synthesis and phospholipase A2 activation.
Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leucine; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Uridine | 1990 |
[Enzyme inhibitors and receptor antagonists in the arachidonic cascade].
Topics: Anti-Inflammatory Agents; Arachidonic Acids; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases; Platelet Activating Factor; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate.
Topics: Aged; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Calcimycin; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Methotrexate; Middle Aged; Neutrophils; Phospholipases; Platelet Activating Factor | 1990 |
Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide.
Topics: Animals; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lactones; Leukotriene B4; Plants, Medicinal; Platelet Activating Factor; Rats; Sesquiterpenes; Thromboxane B2 | 1990 |
Identification of prostaglandin E2 and leukotriene B4 in the synovial fluid of painful, dysfunctional temporomandibular joints.
Topics: Cartilage, Articular; Dinoprostone; Female; Humans; Joint Dislocations; Leukotriene B4; Male; Platelet Activating Factor; Synovial Fluid; Synovitis; Temporomandibular Joint Dysfunction Syndrome | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha involves regulation at a post-cell surface receptor level. Enhancement of the effect of agents which directly activate G
Topics: Complement C5a; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrogen Peroxide; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Cell Surface; Signal Transduction; Sodium Fluoride; Superoxides; Time Factors; Tumor Necrosis Factor-alpha | 1990 |
Enhanced gastric and duodenal platelet-activating factor and leukotriene generation in duodenal ulcer patients.
Topics: Adult; Cimetidine; Duodenal Ulcer; Duodenum; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Leukotriene B4; Male; Middle Aged; Platelet Activating Factor; SRS-A | 1990 |
Platelet-activating factor- and leukotriene B4-induced release of lactoferrin from blood neutrophils of atopic and nonatopic individuals.
Topics: Adult; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Vitro Techniques; Lactoferrin; Lactones; Leukotriene B4; Male; Neutrophils; Plant Extracts; Platelet Activating Factor; Rhinitis; Tetradecanoylphorbol Acetate | 1990 |
Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolaemia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Leukotriene B4; Lipids; Luminescent Measurements; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1990 |
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Effects of a fish oil diet on the metabolism of endogenous (n-6) and (n-3) fatty acids in rat neutrophils.
Topics: Acylation; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Dietary Fats, Unsaturated; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5; Complement C5a, des-Arginine; Dinoprostone; Drug Synergism; Edema; Histamine; Inflammation; Injections, Intradermal; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins E; Rabbits; Rats; Rats, Inbred Lew; Skin; Species Specificity; Substance P | 1985 |
New method for the measurement of eosinophil migration.
Topics: Caseins; Cells, Cultured; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5; Culture Media; Cytological Techniques; Eosinophils; Granulocytes; Humans; Leukotriene B4; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Staining and Labeling | 1987 |
Leukotriene B4, platelet-activating factor and substance P as mediators of acute inflammation.
Topics: Acute Disease; Animals; Cheek; Cricetinae; Inflammation; Leukotriene B4; Mesocricetus; Mouth Mucosa; Muscles; Platelet Activating Factor; Rabbits; Substance P | 1987 |
E-type prostaglandins but not iloprost inhibit platelet activating factor-induced generation of leukotriene B4 by human polymorphonuclear leukocytes.
Topics: Arachidonic Acids; Cardiovascular Agents; Chromatography, High Pressure Liquid; Epoprostenol; Humans; Iloprost; Leukotriene B4; Neutrophils; Platelet Activating Factor; Prostaglandins E | 1989 |
Potent inhibition of leukotriene (LT) B4 release from human polymorphonuclear leukocytes (PMN) by the PGE1-analogue OP-1206.
Topics: Alprostadil; Dinoprostone; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Prostaglandins E, Synthetic | 1988 |
Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism of human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Aristolochic Acids; Calcimycin; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phenanthrenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1989 |
Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils.
Topics: Benzofurans; Calcium; Fura-2; Humans; Leukotriene B4; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nickel; Platelet Activating Factor | 1989 |
Relaxant effect of N-formyl-methionyl-leucyl-phenylalanine on rabbit vascular strips.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Complement C5; Complement C5a; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rabbits; Vasodilation | 1989 |
Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4.
Topics: Bucladesine; Calcitriol; Canavanine; Cell Line; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Leukotriene B4; Luminescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Platelet Activating Factor | 1989 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetates; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phospholipases A; Platelet Activating Factor | 1989 |
Late appearance of phospholipid platelet-activating factor and leukotriene B4 in human skin after repeated antigen challenge.
Topics: Adult; Antigens; Female; Humans; Hypersensitivity, Immediate; Leukotriene B4; Male; Platelet Activating Factor; Pollen; Skin | 1989 |
Simultaneous presence of platelet activating factor, leukotriene B4, prostaglandin F1 alpha and F2 alpha in the supernatant of human neutrophils treated with phospholipase A2 of human monocytes.
Topics: Dinoprost; Humans; Leukotriene B4; Molecular Weight; Monocytes; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandins F | 1989 |
Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin.
Topics: Animals; Arthus Reaction; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Leukotriene B4; Male; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF antagonist L-659,989.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Ethoxyquin; Fatty Acids, Nonesterified; Furans; Hydronephrosis; Inflammation; Kidney; Leukotriene B4; Lipoxygenase Inhibitors; Male; Perfusion; Platelet Activating Factor; Quinolines; Rabbits; Thiophenes; Thromboxane-A Synthase | 1989 |
Comparative studies of human eosinophil migration towards platelet-activating factor and leukotriene B4.
Topics: Cell Movement; Chemotaxis, Leukocyte; Eczema; Eosinophilia; Eosinophils; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Skin Diseases | 1989 |
Flow-cytometric analysis of increased IgE uptake by normal eosinophils following activation with PAF-acether and other inflammatory mediators.
Topics: Antigens, Differentiation, B-Lymphocyte; Eosinophils; Flow Cytometry; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene B4; Platelet Activating Factor; Receptors, Fc; Receptors, IgE; Time Factors | 1989 |
Inflammatory mediators and beta-adrenoceptor function.
Topics: Arachidonic Acids; Cyclic AMP; Humans; Inflammation; Leukotriene B4; Lung; Lymphocytes; Platelet Activating Factor; Radioligand Assay; Receptors, Adrenergic, beta; SRS-A | 1989 |
Characterization of arachidonic acid metabolism, superoxide production, and bacterial killing in bovine circulating neutrophils and elicited alveolar neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Bactericidal Activity; Cattle; Haemophilus; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Staphylococcus epidermidis; Superoxides | 1989 |
Differential sensitivities of purified human eosinophils and neutrophils to defined chemotaxins.
Topics: Adult; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Eosinophils; Glucuronidase; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1989 |
Inflammatory mediators of experimental colitis in rats.
Topics: Animals; Colitis; Colon; Ethanol; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Male; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Trinitrobenzenesulfonic Acid | 1989 |
Platelet-activating factor (PAF) enhances tumor necrosis factor production by alveolar macrophages. Prevention by PAF receptor antagonists and lipoxygenase inhibitors.
Topics: Adjuvants, Immunologic; Animals; Antibody Specificity; Binding, Competitive; Cytotoxicity, Immunologic; Hydroxyeicosatetraenoic Acids; Immune Sera; Immunosuppressive Agents; L Cells; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha | 1989 |
Evidence of PAF-acether metabolic pathway activation in antigen challenge of upper respiratory airways.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Histamine; Humans; Leukotriene B4; Male; Nasal Mucosa; Nasal Provocation Tests; Platelet Activating Factor; Pollen; Radioallergosorbent Test; Rhinitis, Allergic, Seasonal; Skin Tests; Therapeutic Irrigation | 1989 |
Tumor necrosis factor stimulates human neutrophils to release leukotriene B4 and platelet-activating factor. Induction of phospholipase A2 and acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O2-acetyltransferase activity and inhibition by antiproteinase.
Topics: Acetyltransferases; alpha 1-Antichymotrypsin; Enzyme Induction; Humans; Leukotriene B4; Neutrophils; Pancreatic Elastase; Phagocytosis; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protease Inhibitors; Protein Kinases; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1989 |
Synergism between chemotactic peptide and platelet-activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Thromboxane B2 | 1989 |
Arachidonic acid-induced mobilization of calcium in human neutrophils: evidence for a multicomponent mechanism of action.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cholera Toxin; Egtazic Acid; Humans; In Vitro Techniques; Leukotriene B4; Masoprocol; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Virulence Factors, Bordetella | 1989 |
Inhibitory effects of nedocromil sodium on the in vitro induced migration and leukotriene formation of human granulocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Leukotriene B4; Leukotrienes; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; SRS-A; Zymosan | 1989 |
Release of eicosanoids in rat peritoneal cavity stimulated with platelet-activating factor (PAF). Effect of the PAF-antagonist BN-52021.
Topics: Animals; Dinoprostone; Diterpenes; Fatty Acids, Unsaturated; Ginkgolides; Lactones; Leukotriene B4; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Release of PAF-acether and eicosanoids from guinea-pig alveolar macrophages by FMLP: effect of cyclo-oxygenase and lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Benzeneacetamides; Cyclooxygenase Inhibitors; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Alveoli; Pyrazoles; Radioimmunoassay; Thromboxane B2 | 1989 |
Prostaglandin binding sites in human polymorphonuclear neutrophils.
Topics: Dinoprost; Dinoprostone; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Prostaglandin D2; Prostaglandins; Receptors, Prostaglandin | 1989 |
Oscillating actin polymerization/depolymerization responses in human polymorphonuclear leukocytes.
Topics: Actins; Calcium; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Light; Macromolecular Substances; Neutrophils; Platelet Activating Factor; Scattering, Radiation | 1989 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Protein kinase C blockers and neutrophil receptors for leukotriene B4.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Receptors, Leukotriene B4; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thermodynamics | 1989 |
Neutrophils delay functional recovery of the post-hypoxic heart of the rabbit.
Topics: Animals; Heart; Hypoxia; Leukotriene B4; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides | 1989 |
Release of platelet-activating factor and the metabolism of leukotriene B4 by the human neutrophil when studied in a cell superfusion model.
Topics: Acetates; Calcimycin; Cell-Free System; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Leukotriene B4; Models, Biological; Neutrophils; Perfusion; Platelet Activating Factor; Suspensions; Tritium | 1989 |
Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.
Topics: Arachidonic Acids; Humans; Leukotriene B4; Leukotrienes; Models, Biological; Phagocytes; Phagocytosis; Platelet Activating Factor; Thromboxane B2; Zymosan | 1989 |
Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Macromolecular Substances; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Polymers; Prostaglandins; Prostaglandins B; Serum Albumin, Bovine; Structure-Activity Relationship; Umbilical Veins | 1989 |
[Effects of tetrandrine on cytoplasmic free calcium in rat neutrophils].
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcimycin; Calcium; Calcium Channel Blockers; Leukotriene B4; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1989 |
1-O-alkyl-2-N-methylcarbamyl-glycerophosphocholine: a biologically potent, non-metabolizable analog of platelet-activating factor.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; In Vitro Techniques; Leukotriene B4; Neutrophils; Phospholipases A; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship | 1987 |
Oscillatory motion in human neutrophils responding to chemotactic stimuli.
Topics: Androstadienes; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; In Vitro Techniques; Leukotriene B4; Locomotion; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Nephelometry and Turbidimetry; Neutrophils; Platelet Activating Factor | 1987 |
Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage.
Topics: Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Leukotriene B4; Macrophages; Masoprocol; Methionine; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Zymosan | 1987 |
Anaphylactic release of platelet activating factor acether and eicosanoids from lungs of guinea pigs sensitized to ovalbumin aerosol.
Topics: Anaphylaxis; Animals; Fatty Acids, Unsaturated; Guinea Pigs; Leukotriene B4; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Thromboxane B2 | 1987 |
Pharmacological evidence for a role of lipoxygenase products in platelet-activating factor (PAF)-induced hyperalgesia.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hyperalgesia; Hyperesthesia; Leukotriene B4; Lipoxygenase; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1987 |
Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Dinoprostone; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Leukotriene B4; Lung; Platelet Activating Factor; Prostaglandins E; SRS-A; Thromboxane B2 | 1987 |
Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.
Topics: Amines; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Palmitoylcarnitine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1987 |
Modulation of leucocyte activation in the early phase of the rabbit burn injury.
Topics: Animals; Burns; Calcimycin; Disease Models, Animal; Diterpenes; Free Radicals; Ginkgolides; Lactones; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides | 1988 |
Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate.
Topics: Calcium; Cholera Toxin; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Receptors, Prostaglandin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Diacylglycerols modulate human polymorphonuclear neutrophil responsiveness: effects on intracellular calcium mobilization, granule exocytosis, and superoxide anion production.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzofurans; Calcium; Cytochalasin B; Cytoplasmic Granules; Diglycerides; Dose-Response Relationship, Drug; Exocytosis; Fura-2; Glycerides; Humans; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Platelet Activating Factor; Superoxides | 1988 |
Effects of inflammatory mediators on neuromuscular transmission in canine trachea in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Spasm; Dogs; In Vitro Techniques; Leukotriene B4; Muscle, Smooth; Ozone; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; SRS-A; Synaptic Transmission; Thromboxane A2; Trachea | 1988 |
Release of leukotrienes from porcine and human blood vessels by immunological and nonimmunological stimuli.
Topics: Animals; Antibodies, Anti-Idiotypic; Blood Vessels; Calcimycin; Cerebral Arteries; Coronary Circulation; Coronary Vessels; Female; Humans; Immunoglobulin E; Immunoglobulin G; Indomethacin; Leukotriene B4; Leukotriene E4; Platelet Activating Factor; Pulmonary Artery; SRS-A; Swine | 1988 |
Role of lipoxygenase metabolites of arachidonic acid in T cell activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclic GMP; Humans; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxygenase; Lymphocyte Activation; Mice; Platelet Activating Factor; T-Lymphocytes | 1988 |
Platelet activating factor and leukotriene B4 induce hyperpolarization of human endothelial cells but depolarization of neutrophils.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Thromboxane effects on canine trachealis neuromuscular function.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Leukotriene B4; Male; Muscle, Smooth; Neuromuscular Junction; Platelet Activating Factor; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; SRS-A; Thromboxane A2; Trachea | 1988 |
Leukotriene B4-induced homologous desensitization of calcium mobilization and phosphoinositide metabolism in U-937 cells.
Topics: Animals; Calcium; Cell Line; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositols; Platelet Activating Factor; Receptors, Immunologic; Receptors, Leukotriene B4; SRS-A; Virulence Factors, Bordetella | 1988 |
Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Separation; Concanavalin A; Cytoplasm; Digitonin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Protons; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
Platelet activating factor increases expression of complement receptors on human neutrophils.
Topics: Calcium; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Receptors, Complement; Receptors, Complement 3b | 1988 |
Gastrointestinal damage induced by platelet-activating factor: role of leukotrienes.
Topics: Animals; Dexamethasone; Gastrointestinal Diseases; Hemodynamics; Leukotriene B4; Male; Peroxidase; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer | 1988 |
Agonist-induced calcium flux, phosphoinositide metabolism, aggregation and enzyme secretion in human neutrophils.
Topics: Adult; Calcium; Cell Aggregation; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Platelet Activating Factor | 1988 |
SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Depression, Chemical; Dinoprostone; Disease Models, Animal; Enterocolitis, Pseudomembranous; Leukotriene B4; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins; Rabbits; Superoxide Dismutase; Thromboxane B2 | 1988 |
Inhibition of eicosanoid and PAF formation by dexamethasone in rat inflammatory polymorphonuclear neutrophils may implicate lipocortin 's'.
Topics: Annexins; Calcimycin; Dexamethasone; Dinoprostone; Glycoproteins; Humans; Inflammation; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1988 |
Leukotriene C4 production from human eosinophils in vitro. Role of eosinophil chemotactic factors on eosinophil activation.
Topics: Adult; Calcimycin; Cells, Cultured; Chemotactic Factors; Chemotactic Factors, Eosinophil; Enzyme Activation; Eosinophils; Female; Humans; Leukotriene B4; Male; Phosphatidylserines; Platelet Activating Factor; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1988 |
Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction.
Topics: Exocytosis; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepstatins; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Effect of dietary fish oils on the formation of leukotriene B4 and B5, thromboxane and platelet activating factor by rat leukocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diet; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; In Vitro Techniques; Leukocytes; Leukotriene B4; Lipoxygenase; Male; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1988 |
Gossypol: a potent inhibitor of PAF-acether- and leukotriene-induced contractions of guinea-pig lung parenchyma strips.
Topics: Animals; Diterpenes; Ginkgolides; Gossypol; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lactones; Leukotriene B4; Lung; Male; Masoprocol; Muscle Contraction; Plant Extracts; Platelet Activating Factor; Respiratory Muscles; SRS-A | 1987 |
Ketoconazole, leukotrienes, Paf-acether and nicotine as a hapten: the possible aetiology of seborrhoeic dermatitis.
Topics: Acquired Immunodeficiency Syndrome; Antipsychotic Agents; Dermatitis, Seborrheic; Haptens; Humans; Ketoconazole; Leukotriene B4; Malassezia; Models, Biological; Nicotine; Platelet Activating Factor | 1987 |
Aggregating and prostanoid-releasing effects of platelet-activating factor and leukotrienes on human polymorphonuclear leukocytes and platelets.
Topics: Cell Aggregation; Dinoprostone; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2 | 1985 |
Neutrophil degranulation: evidence pertaining to its mediation by the combined effects of leukotriene B4, platelet-activating factor, and 5-HETE.
Topics: Animals; Calcimycin; Complement C5; Complement C5a; Cytoplasmic Granules; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits | 1985 |
Activation of NADPH oxidase in human neutrophils. Synergism between fMLP and the neutrophil products PAF and LTB4.
Topics: Drug Synergism; Enzyme Activation; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Superoxides; Time Factors | 1985 |
A simple method for studying chemotaxis, vascular permeability and histological modifications induced by mediators of inflammation in vivo in man.
Topics: Capillary Permeability; Chemotaxis, Leukocyte; Dermatitis, Contact; Humans; Leukotriene B4; Methods; Platelet Activating Factor; Skin | 1985 |
Exclusive leukotriene C4 synthesis by purified human eosinophils induced by opsonized zymosan.
Topics: Calcimycin; Eosinophils; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Platelet Activating Factor; SRS-A; Zymosan | 1985 |
Synergistic inhibition of complement induced granulocyte margination by BW755C and calcium channel blockers.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Agranulocytosis; Animals; Calcium; Calcium Channel Blockers; Cell Aggregation; Chemotactic Factors; Complement System Proteins; Female; Granulocytes; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyrazoles; Rabbits; Verapamil | 1985 |
[Mediators of immediate anaphylactic reactions].
Topics: Anaphylaxis; Chemotactic Factors; Enzymes; Histamine; Humans; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Proteoglycans; SRS-A | 1985 |
Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation.
Topics: Animals; Bronchi; Dogs; In Vitro Techniques; Leukotriene B4; Methacrylates; Neutrophils; Platelet Activating Factor; Respiratory System; Thromboxanes | 1986 |
Human endothelial cells inhibit granulocyte aggregation in vitro.
Topics: Blood Coagulation Factors; Cell Aggregation; Cells, Cultured; Dinoprostone; Endothelium; Epoprostenol; Granulocytes; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; SRS-A | 1986 |
Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.
Topics: Animals; Chromones; Diphenhydramine; Dose-Response Relationship, Drug; Guinea Pigs; Hematocrit; Hemorrhage; Histamine; Injections, Intravenous; Leukotriene B4; Male; Phospholipid Ethers; Plasma; Platelet Activating Factor; SRS-A; Thiazoles; Time Factors | 1986 |
Leukocyte stimulation: receptor, membrane, and metabolic events. Introduction and summary.
Topics: Cell Membrane; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Leukotriene B4; Superoxides; Type C Phospholipases; Virulence Factors, Bordetella | 1986 |
Platelet-activating factor and leukotriene biosynthesis is inhibited in polymorphonuclear leukocytes depleted of arachidonic acid.
Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dietary Fats; Leukotriene B4; Neutrophils; Oligopeptides; Platelet Activating Factor; Rats | 1986 |
Leukotriene B4 biosynthesis in polymorphonuclear leukocytes from blood of umbilical cord, infants, children, and adults.
Topics: Adolescent; Adult; Aging; Calcimycin; Child; Child, Preschool; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Leukotriene B4; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1986 |
Platelet-activating factor as a stimulus of exocytosis in human neutrophils.
Topics: Cytochalasin B; Dose-Response Relationship, Drug; Exocytosis; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Time Factors | 1986 |
Potentiation of 5-lipoxygenase metabolism by human neutrophils using a combination of activators.
Topics: Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Drug Synergism; Humans; Leukotriene B4; Leukotrienes; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1986 |
The effect of endogenous eicosapentaenoic acid on PMN leukotriene and PAF biosynthesis.
Topics: Animals; Diet; Eicosapentaenoic Acid; Fish Oils; Leukotriene B4; Neutrophils; Platelet Activating Factor; Rats | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Comparative effects of leukotrienes and PAF-acether electrophysiological activity of the rat retina.
Topics: Animals; Electroretinography; Leukotriene B4; Membrane Potentials; Photoreceptor Cells; Platelet Activating Factor; Rats; Retina; SRS-A | 1986 |
Stimulus amplification by PAF and LTB4 in human neutrophils.
Topics: Calcium; Chemotaxis, Leukocyte; Diterpenes; Drug Synergism; Ginkgolides; Humans; In Vitro Techniques; Lactones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Platelet Activating Factor | 1986 |
Comparative effects of drugs on leukotrienes-, PAF-acether- and histamine- induced contractions of guinea-pig lung parenchymal strips.
Topics: Animals; Chromones; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene B4; Lung; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A | 1986 |
Chemical mediators of anaphylaxis released by alveolar macrophages in bronchial asthma.
Topics: Anaphylaxis; Arachidonic Acid; Arachidonic Acids; Asthma; Blood Proteins; Humans; Leukotriene B4; Macrophages; Platelet Activating Factor; Pulmonary Alveoli | 1986 |
Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils.
Topics: Cell Movement; Chemotactic Factors; Chemotactic Factors, Eosinophil; Eosinophils; Humans; In Vitro Techniques; Leukotriene B4; Platelet Activating Factor | 1986 |
Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Membrane; Cell-Free System; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protamine Kinase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Solubility; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Effects of platelet activating factor on the chemotaxis of normodense eosinophils from normal subjects.
Topics: Adult; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Diterpenes; Eosinophils; Ginkgolides; Humans; Lactones; Leukotriene B4; Male; Plant Extracts; Platelet Activating Factor | 1987 |
G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cell-Free System; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Stimulated release of neutral proteinases elastase and cathepsin G from inflammatory rat polymorphonuclear leukocytes.
Topics: Animals; Calcimycin; Cathepsin G; Cathepsins; Cytoplasmic Granules; Dose-Response Relationship, Drug; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serine Endopeptidases | 1987 |
Lack of correlation between calcium mobilization and respiratory burst activation induced by chemotactic factors in rabbit polymorphonuclear leukocytes.
Topics: Animals; Calcium; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Kinetics; Leukotriene B4; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Rabbits; Superoxides | 1987 |
Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Vessels; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lactones; Leukotriene B4; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thromboxane A2; Time Factors; Vasoconstriction | 1987 |
Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism.
Topics: Calcimycin; Cell Adhesion; Cell Aggregation; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Solubility | 1987 |
Biologic properties of LTB4 and paf-acether in vivo in human skin.
Topics: Capillary Permeability; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Osmolar Concentration; Platelet Activating Factor; Skin | 1987 |
Desensitization and antagonism of rat polymorphonuclear leukocytes stimulated with PAF acether.
Topics: Animals; Cells, Cultured; Cytochalasin B; Diterpenes; Exocytosis; Ginkgolides; Glucuronidase; Lactones; Leukotriene B4; Male; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Evidence for a dual pathway in platelet activating factor-induced aggregation of rat polymorphonuclear leucocytes.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cell Aggregation; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Platelet Activating Factor; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains | 1987 |
Leukotrienes do not modify the effects of PAF on human platelet aggregation.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Humans; Leukotriene B4; Platelet Activating Factor; Platelet Aggregation; SRS-A; Thromboxane B2 | 1987 |
Signalling for increased cytoskeletal actin in neutrophils.
Topics: Actins; Animals; Calcimycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Pertussis Toxin; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Mechanisms of vascular actions of PAF.
Topics: Animals; Cerebrovascular Circulation; Coronary Circulation; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukotriene B4; Platelet Activating Factor; Rats; SRS-A; Swine | 1987 |
Effect of group B streptococcal type-specific antigen on polymorphonuclear leukocyte function and polymorphonuclear leukocyte-endothelial cell interaction.
Topics: Antigens, Bacterial; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Complement System Proteins; Endothelium; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Streptococcus agalactiae; Zymosan | 1987 |
The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process.
Topics: Ethers; Humans; Hydrogen Peroxide; Ionomycin; Kinetics; Leukotriene B4; Luminescent Measurements; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1987 |
Desensitization of acute inflammatory lesions to chemotaxins and endotoxin.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
Various authentic chemoattractants mediating leukocyte adherence inhibition.
Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Complement C5a, des-Arginine; Humans; Leukocyte Adherence Inhibition Test; Leukocytes; Leukotriene B4; Liver Neoplasms; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Acetyl glyceryl ether phosphorylcholine (PAF-acether) and leukotriene B4-mediated neutrophil chemotaxis through an intact endothelial cell monolayer.
Topics: Arachidonate Lipoxygenases; Cells, Cultured; Chemotaxis, Leukocyte; Endothelium; Epoprostenol; Humans; Kinetics; Leukotriene B4; Lipoxygenase; Microscopy, Electron, Scanning; Neutrophils; Platelet Activating Factor; Prostaglandins, Synthetic; SRS-A | 1984 |
Interdependence of inflammatory signals in various immunological systems.
Topics: Animals; Complement C5; Complement C5a; Eosinophils; Guinea Pigs; Histamine Release; Humans; Immunity, Cellular; Inflammation; Leukotriene B4; Muscle Contraction; Neutrophils; Platelet Activating Factor; Rats | 1983 |
Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Humans; In Vitro Techniques; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Evidence for 5, 12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation.
Topics: Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Kinetics; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1981 |
Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis in human polymorphonuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Catechols; Cell Aggregation; Chromatography, Gas; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Masoprocol; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1982 |
[Mediators of inflammation. Their nature and their role].
Topics: Anti-Inflammatory Agents; Bradykinin; Histamine; Humans; Inflammation; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Serotonin | 1982 |
Neutrophil aggregating properties of PAF-acether and leukotriene B4.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Cell Aggregation; Dose-Response Relationship, Drug; Indomethacin; Leukotriene B4; Male; Masoprocol; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1983 |
Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis and cyclic AMP accumulation in human polymorphonuclear leukocytes.
Topics: Cell Aggregation; Cyclic AMP; Humans; Indomethacin; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor | 1983 |
Evidence for mediation of acetyl glyceryl ether phosphorylcholine stimulation of adenosine 3',5'-(cyclic)monophosphate levels in human polymorphonuclear leukocytes by leukotriene B4.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Arachidonic Acids; Cyclic AMP; Enzyme Activation; Epinephrine; Humans; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Sodium Fluoride; Swine | 1983 |
Lipid and peptide mediators of inflammation. Summary.
Topics: Animals; Humans; Inflammation; Leukotriene B4; Peptide Hydrolases; Platelet Activating Factor; SRS-A | 1983 |
Antigen-initiated release of platelet-activating factor (PAF-acether) from mouse bone marrow-derived mast cells sensitized with monoclonal IgE.
Topics: Animals; Antigens; Bone Marrow Cells; Calcimycin; Hexosaminidases; Immunoglobulin E; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Platelet Activating Factor; SRS-A | 1983 |
Increased monocyte chemotaxis towards leukotriene B4 and platelet activating factor in patients with inflammatory dermatoses.
Topics: Adolescent; Adult; Cells, Cultured; Chemotaxis, Leukocyte; Child; Dermatitis; Dermatitis, Atopic; Dose-Response Relationship, Immunologic; Female; Humans; Leukotriene B4; Male; Monocytes; Platelet Activating Factor; Psoriasis; Urticaria | 1983 |
Neutrophil degranulation responses to combinations of arachidonate metabolites and platelet-activating factor.
Topics: Arachidonic Acids; Cytoplasmic Granules; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotriene B4; Leukotrienes; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1984 |
Stimulation of the human neutrophil superoxide anion-generating system with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine.
Topics: Calcium; Cytochalasin B; Dose-Response Relationship, Drug; Egtazic Acid; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides | 1984 |
Acetylglycerylether phosphorylcholine-(AGEPC) and leukotriene B4-stimulated cyclic AMP levels in human polymorphonuclear leukocytes.
Topics: Adenylyl Cyclases; Arachidonate Lipoxygenases; Cell Aggregation; Cyclic AMP; Cyclooxygenase Inhibitors; Epoprostenol; Feedback; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor | 1984 |
Comparative differences and combined effects of interleukin-8, leukotriene B4, and platelet-activating factor on neutrophil chemotaxis of the newborn.
Topics: Adult; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Drug Synergism; Humans; Infant, Newborn; Interleukin-8; Leukotriene B4; Neutrophils; Platelet Activating Factor; Reference Values | 1995 |
Interaction between nitric oxide and superoxide: role in modulating leukocyte adhesion in the postischemic microvasculature.
Topics: Animals; Cell Adhesion; Endothelium, Vascular; Free Radicals; Humans; Intestine, Small; Ischemia; Leukocytes; Leukotriene B4; Microcirculation; Models, Biological; Nitrates; Nitric Oxide; Phospholipases A; Platelet Activating Factor; Reperfusion; Superoxides | 1995 |
Inhibition of leukotriene C4 and B4 release by human eosinophils with the new 5-lipoxygenase inhibitor 6-hydroxy-2(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride.
Topics: Asthma; Calcimycin; Dose-Response Relationship, Drug; Eosinophils; Humans; In Vitro Techniques; Ionophores; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Platelet Activating Factor; Thiazoles | 1995 |
Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats.
Topics: Aminophylline; Animals; Antigens; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Female; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity; Leukocyte Count; Leukotriene B4; Male; Muscle Relaxation; Muscle, Smooth; Passive Cutaneous Anaphylaxis; Phosphodiesterase Inhibitors; Platelet Activating Factor; Purinones; Rats; Rats, Wistar; Superoxides; Trachea | 1993 |
Regulation of monocyte integrin expression by beta-family chemokines.
Topics: Calcium; CD18 Antigens; Cell Adhesion; Chemotactic Factors; Cytokines; Flow Cytometry; GTP-Binding Proteins; Humans; In Vitro Techniques; Integrins; Interleukin-1; Leukotriene B4; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Up-Regulation | 1994 |
SB 203347, an inhibitor of 14 kDa phospholipase A2, alters human neutrophil arachidonic acid release and metabolism and prolongs survival in murine endotoxin shock.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Arachidonic Acid; Cell-Free System; Disease Models, Animal; Enzyme Inhibitors; Humans; Leukotriene B4; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic; Sulfonamides; Survivors | 1995 |
Rapid oscillations of actin polymerization/depolymerization in polymorphonuclear leukocytes stimulated by leukotriene B4 and platelet-activating factor.
Topics: Actins; Cell Count; Humans; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Polymers | 1995 |
Effect of different platelet agonists on intracellular free Ca++ concentrations in human tumor cells: possible role in tumor growth.
Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Blood Platelets; Calcium; Cell Communication; Cell Division; Collagen; HeLa Cells; Humans; Intracellular Fluid; Leukotriene B4; Melanoma; Mesothelioma; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet-Derived Growth Factor; Thrombin; Thromboxane B2; Tumor Cells, Cultured; Verapamil | 1995 |
Bradykinin stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity.
Topics: Animals; Bradykinin; Bronchi; Cattle; Chemokine CCL2; Chemotactic Factors; Epithelium; Interleukin-8; Leukotriene B4; Osmolar Concentration; Platelet Activating Factor | 1995 |
Leukotriene synthesis in calcium-depleted human neutrophils: arachidonic acid release correlates with calcium influx.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Chromatography, High Pressure Liquid; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Leukotrienes; Mass Spectrometry; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Platelet Activating Factor | 1995 |
Nicotine inhibits cytokine synthesis by mouse colonic mucosa.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Colitis, Ulcerative; Colon; Cytokines; Dinoprostone; Female; Interleukin-1; Intestinal Mucosa; Leukotriene B4; Leukotriene C4; Mice; Mice, Inbred BALB C; Nicotine; Platelet Activating Factor; Prostaglandins; Thromboxane B2; Tumor Necrosis Factor-alpha | 1995 |
Leukotriene B4 mediates substance P-induced granulocyte infiltration into mouse skin. Comparison with antigen-induced granulocyte infiltration.
Topics: Animals; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophils; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin Physiological Phenomena; Substance P | 1993 |
Anti-inflammatory activities of Emblica officinalis Gaertn leaf extracts.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemistry Techniques, Analytical; Dextrans; Edema; Leukotriene B4; Methanol; Neutrophils; Plant Extracts; Plants, Medicinal; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Water | 1993 |
Role of leukotriene B4 in substance P-induced granulocyte infiltration in mouse skin.
Topics: Animals; Granulocytes; Leukotriene B4; Mast Cells; Mice; Mice, Inbred BALB C; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin; Skin Physiological Phenomena; Substance P | 1993 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Platelet-activating factor mediates trinitrobenzene induced colitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Colitis; Colon; Dinoprostone; Eicosanoids; Gastrointestinal Contents; Leukotriene B4; Platelet Activating Factor; Rabbits; Second Messenger Systems; Thromboxane B2; Triazoles; Trinitrobenzenesulfonic Acid | 1994 |
CD11/CD18-independent transendothelial migration of human polymorphonuclear leukocytes and monocytes: involvement of distinct and unique mechanisms.
Topics: Antibodies, Monoclonal; CD11 Antigens; CD8 Antigens; Cell Migration Inhibition; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Endothelium, Vascular; Humans; Interleukin-1; Interleukin-8; Leukotriene B4; Monocytes; Neutrophils; Platelet Activating Factor | 1995 |
Ketotifen and nitroxides decrease capsaicin-augmented ethanol-induced gastric damage in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Cyclic N-Oxides; Ethanol; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Ketotifen; Leukotriene B4; Leukotriene C4; Male; Mast Cells; Nerve Fibers; Platelet Activating Factor; Premedication; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Spin Labels; Stomach Ulcer | 1995 |
Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells.
Topics: Azepines; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Triazoles; Umbilical Veins; Virulence Factors, Bordetella | 1995 |
Evidence for the predominant role of intracellular PAF binding sites in the regulation of phospholipase A2 in human neutrophils.
Topics: Alkaloids; Azepines; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles | 1995 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
5-Oxo-eicosanoids are potent eosinophil chemotactic factors. Functional characterization and structural requirements.
Topics: Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eicosanoic Acids; Eosinophilia; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indicators and Reagents; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Structure-Activity Relationship | 1995 |
Comparative studies indicate that platelet-activating factor is a relatively weak eosinophilotactic mediator.
Topics: Adult; Cells, Cultured; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Endothelium, Vascular; Eosinophils; Epithelial Cells; Female; Humans; Leukotriene B4; Lung; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Umbilical Veins | 1995 |
Effect of in vivo desensitization to leukotriene B4 on eosinophil infiltration in response to C5a in guinea-pig skin.
Topics: Amitrole; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Complement C5a; Eosinophils; Guinea Pigs; In Vitro Techniques; Inflammation Mediators; Leukotriene B4; Male; Neutrophils; Peroxidases; Platelet Activating Factor; Recombinant Proteins; Skin | 1994 |
Acetic acid-induced colitis in normal and essential fatty acid deficient rats.
Topics: Acetates; Acetic Acid; Acid Phosphatase; Animals; Colitis; Dietary Fats; Dinoprostone; Fatty Acids; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Wistar | 1995 |
IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody.
Topics: Animals; Antibodies, Monoclonal; Calcium; Chemotaxis, Leukocyte; Dactinomycin; Dihydropyridines; Edema; Eosinophils; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Skin | 1995 |
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan | 1994 |
Characterization of eosinophil homotypic aggregation.
Topics: Animals; Calcium; CD18 Antigens; Cell Aggregation; Drug Synergism; Eosinophils; Guinea Pigs; Leukotriene B4; Magnesium; Microscopy; Platelet Activating Factor; Pyrimidinones; Stimulation, Chemical; Superoxides; Thiazoles | 1995 |
Role of interleukin-5 in enhanced migration of eosinophils from airways of immunized guinea-pigs.
Topics: Animals; Antibodies, Monoclonal; Antigens; Bronchoalveolar Lavage Fluid; Cell Movement; Eosinophils; Guinea Pigs; Immunization; Interleukin-5; Leukotriene B4; Male; Nedocromil; Ovalbumin; Platelet Activating Factor | 1994 |
The inhibitory effect of methotrexate on PAF-induced neutrophil and eosinophil locomotion in asthmatic patients.
Topics: Asthma; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Humans; Leukocytes, Mononuclear; Leukotriene B4; Methotrexate; Neutrophils; Platelet Activating Factor | 1994 |
Relationship between nasal resistance and airway hyperreactivity following nasal provocation with Dermatophagoides pteronyssinus in allergic rhinitis.
Topics: Adolescent; Adult; Allergens; Antigens, Dermatophagoides; Bronchial Hyperreactivity; Eosinophils; Female; Glycoproteins; Humans; Leukocyte Count; Leukotriene B4; Leukotriene C4; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Platelet Activating Factor; Rhinitis, Allergic, Perennial | 1995 |
The effect of Clostridium difficile toxin on colonocyte prostanoid activity.
Topics: 6-Ketoprostaglandin F1 alpha; Bacterial Proteins; Bacterial Toxins; Cell Line, Transformed; Colon; Culture Media; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Humans; Indomethacin; Leukotriene B4; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane B2 | 1994 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Capillary filtration during acute inflammation: role of adherent neutrophils.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Capillaries; CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Filtration; Inflammation; Leukotriene B4; Male; Muscle, Smooth, Vascular; Neutrophils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Receptors, Leukocyte-Adhesion; Splanchnic Circulation | 1993 |
Modulation of leukocyte migration in mesenteric interstitium.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cephalosporins; Chemotaxis, Leukocyte; Ischemia; Leukocytes; Leukotriene B4; Male; Microscopy, Video; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reperfusion; Serpins; Serum Albumin; Splanchnic Circulation; Time Factors | 1994 |
Changes of cytosolic calcium ion concentrations in human endothelial cells in response to thrombin, platelet-activating factor, and leukotriene B4.
Topics: Azepines; Calcium; Cells, Cultured; Cytosol; Endothelium, Vascular; Fura-2; Humans; Ions; Leukotriene B4; Osmolar Concentration; Platelet Activating Factor; Thrombin; Triazoles | 1994 |
Determinants of neutrophil HOCl generation: ligand-dependent responses and the role of surface adhesion.
Topics: Cell Adhesion; Cell Membrane; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Injections, Intraperitoneal; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Phospholipid Ethers; Platelet Activating Factor; Premedication; Prosencephalon; Rats; Rats, Wistar; Reperfusion Injury | 1994 |
Chemotactic peptide down-regulation of calcium mobilization induced by platelet-activating factor and by leukotriene B4 in human neutrophils is uncovered by protein phosphatase inhibitors.
Topics: Alkaloids; Calcium; Down-Regulation; Ethers, Cyclic; Humans; Indoles; Leukotriene B4; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine | 1994 |
BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.
Topics: Arachidonic Acid; Benzoxazoles; Calcimycin; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1994 |
Human neutrophil degranulation responses to nucleotides.
Topics: Adenine Nucleotides; Adenosine; Arachidonic Acids; Cytoplasmic Granules; Diglycerides; Drug Synergism; Humans; In Vitro Techniques; Ionomycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Ribonucleotides; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 1994 |
Phospholipid metabolite expression by head and neck squamous cell carcinoma.
Topics: Aged; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Dinoprostone; Epidermal Growth Factor; Evaluation Studies as Topic; Fibroblasts; Head and Neck Neoplasms; Humans; Immune Tolerance; Interleukin-1; Leukotriene B4; Lipopolysaccharides; Middle Aged; Neoplasm Staging; Phenotype; Platelet Activating Factor; Radioimmunoassay; Regression Analysis; Tumor Cells, Cultured | 1994 |
Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations.
Topics: Calcium; Cell Communication; Cell Movement; Chemotactic Factors; Complement C5a; Drug Synergism; Humans; Interleukin-8; Leukotriene B4; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1994 |
Autocrine enhancement of leukotriene synthesis by endogenous leukotriene B4 and platelet-activating factor in human neutrophils.
Topics: Amino Acid Sequence; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Complement C5a; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotriene B4; Leukotrienes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Modulation of the enhanced migration of eosinophils from the airways of sensitized guinea pigs: role of IL-5.
Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Immunization; Interleukin-5; Leukotriene B4; Male; Ovalbumin; Platelet Activating Factor | 1994 |
Inhibitory effect of cyclosporin A on eosinophil infiltration in the guinea-pig lung induced by antigen, platelet-activating factor and leukotriene B4.
Topics: Animals; Antigens; Betamethasone; Cyclosporine; Eosinophils; Guinea Pigs; Leukotriene B4; Lung; Male; Platelet Activating Factor; Pulmonary Eosinophilia | 1994 |
Eosinophils recruited to the lung by segmental antigen challenge show a reduced chemotactic response to leukotriene B4.
Topics: Allergens; Antigens, Plant; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Humans; In Vitro Techniques; Leukotriene B4; Lung; N-Formylmethionine Leucyl-Phenylalanine; Plant Proteins; Platelet Activating Factor | 1994 |
13-HODE inhibits the intracellular calcium increase of activated human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcium; Humans; Intracellular Fluid; Leukotriene B4; Linoleic Acids; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1994 |
A novel syndrome of severe neutrophil dysfunction: unresponsiveness confined to chemotaxin-induced functions.
Topics: Actins; Antigens, CD; Calcimycin; Calcium; CD18 Antigens; CD4 Antigens; CD8 Antigens; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Cytochalasin B; Endothelium, Vascular; Female; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; Infant, Newborn; Kinetics; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Reference Values; Sepsis; Syndrome; T-Lymphocyte Subsets | 1993 |
Effects of NZ-107 on airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Interleukin-5; Leukocytes; Leukotriene Antagonists; Leukotriene B4; Lymphocytes; Macrophages, Alveolar; Male; Neutrophils; Platelet Activating Factor; Prednisolone; Pyridazines; Superoxides | 1993 |
Molecular determinants of aspirin-induced neutrophil adherence to endothelial cells.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Aspirin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Flow Cytometry; Fluorescent Antibody Technique; Humans; Infant, Newborn; Intercellular Adhesion Molecule-1; Leukotriene B4; Neutrophils; Platelet Activating Factor; Umbilical Veins | 1993 |
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation.
Topics: Calcimycin; Calcium; Cell Aggregation; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Interactions between synthesis of platelet-activating factor and leukotriene B4 in isolated human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Azepines; Calcimycin; Chemotaxis, Leukocyte; Drug Interactions; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Cyclic-AMP level and eicosanoid release from alveolar macrophages are differentially affected by high and low dose of platelet activating factor.
Topics: Animals; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor | 1994 |
Central neurogenic antiinflammatory action of alpha-MSH: modulation of peripheral inflammation induced by cytokines and other mediators of inflammation.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Edema; Female; Inflammation; Injections, Intraventricular; Interleukin-1; Interleukin-8; Leukotriene B4; Mice; Mice, Inbred BALB C; Platelet Activating Factor | 1994 |
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil.
Topics: Benzoquinones; Cell Line; Chemotactic Factors; Complement C5a; Humans; In Vitro Techniques; Interleukin-8; Lactams, Macrocyclic; Leukotriene B4; Models, Biological; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Quinones; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Effect of a new de-N-acetyl-lysoglycosphingolipid on chemically-induced inflammatory bowel disease: possible mechanism of action.
Topics: Animals; Arachidonic Acid; Carbohydrate Sequence; Colitis; Colon; Gangliosides; Humans; Inflammatory Bowel Diseases; Leukotriene B4; Male; Malondialdehyde; Molecular Sequence Data; Organ Size; Pancreas; Peroxidase; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Spleen; Synovial Fluid; Trinitrobenzenesulfonic Acid | 1993 |
Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor.
Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Gel; Chromatography, Ion Exchange; Complement C5a; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-8; Isoenzymes; Leukotriene B4; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Platelet Activating Factor; Point Mutation; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Molecular determinants of lipid mediator-induced leukocyte adherence and emigration in rat mesenteric venules.
Topics: Animals; Antibodies, Monoclonal; Cell Adhesion; Cell Movement; Hemodynamics; Leukocytes; Leukotriene B4; Lipids; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Venules | 1994 |
Role of eosinophil activation in the bronchial reactivity of allergic guinea pigs.
Topics: Animals; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Leukotriene B4; Male; Methacholine Chloride; Ovalbumin; Peroxidases; Platelet Activating Factor; Proteins; Respiratory Hypersensitivity; Ribonucleases | 1994 |
Inflammatory effects of ozone in the upper airways of subjects with asthma.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukotriene B4; Male; Nasal Lavage Fluid; Ozone; Platelet Activating Factor; Respiratory Mechanics; Respiratory System | 1994 |
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Culture Techniques; Edetic Acid; Eicosanoids; Ileum; Indomethacin; Kinetics; Leukotriene B4; Leukotriene D4; Male; Permeability; Platelet Activating Factor; Rats; Rats, Wistar | 1994 |
Nitric oxide prevents leukocyte adherence: role of superoxide.
Topics: Animals; Cell Adhesion; Free Radical Scavengers; Hypoxanthine; Hypoxanthines; Leukocytes; Leukotriene B4; Male; Mesentery; Microcirculation; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Hepoxilin A3 inhibits the rise in free intracellular calcium evoked by formyl-methionyl-leucyl-phenylalanine, platelet-activating factor and leukotriene B4.
Topics: 8,11,14-Eicosatrienoic Acid; Calcium; Calcium-Transporting ATPases; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Stereoisomerism; Terpenes; Thapsigargin | 1993 |
Regulation of human neutrophil aggregation: comparable latent times, activator sensitivities, and exponential decay in aggregability for FMLP, platelet-activating factor, and leukotriene B4.
Topics: Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Induction by chemokines of lipid mediator synthesis in granulocyte-macrophage colony-stimulating factor-treated human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; beta-Thromboglobulin; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukotriene B4; Neutrophils; Peptides; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
Signal transduction mechanisms for leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils.
Topics: Cations, Divalent; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; GTP-Binding Proteins; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Receptors, Leukotriene B4; Signal Transduction | 1994 |
Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzopyrans; Colitis; Colon; Dinoprostone; Disease Models, Animal; Leukotriene B4; Platelet Activating Factor; Radioimmunoassay; Saguinus; Thromboxane B2 | 1993 |
Lipid mediator production in acute and chronic pancreatitis in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chronic Disease; Dinoprostone; Diterpenes; Eicosanoids; Ginkgolides; Lactones; Leukotriene B4; Ligation; Male; Masoprocol; Pancreatic Ducts; Pancreatitis; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Thromboxane B2 | 1994 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Platelet-activating factor-induced human eosinophil transendothelial migration: evidence for a dynamic role of the endothelium.
Topics: Azepines; Cells, Cultured; Chemotaxis, Leukocyte; Endothelium, Vascular; Eosinophils; Humans; Leukotriene B4; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Triazoles | 1993 |
Leukocyte adherence in rat mesenteric venules: effects of adenosine and methotrexate.
Topics: Adenosine; Animals; Cell Adhesion; Endothelium, Vascular; Leukocyte Adherence Inhibition Test; Leukocytes; Leukotriene B4; Male; Methotrexate; Platelet Activating Factor; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Venules | 1993 |
Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production. Influence of duration and dosage.
Topics: Adult; Dietary Fats; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Fatty Acids; Fatty Acids, Omega-3; Fish Oils; Humans; Kinetics; Leukotriene B4; Lipids; Male; Neutrophils; Phospholipids; Platelet Activating Factor; Reference Values; Time Factors | 1993 |
Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM).
Topics: 6-Ketoprostaglandin F1 alpha; Allantois; Animals; Arachidonic Acid; Calcium; Cattle; Chorion; Chromatography, High Pressure Liquid; Dinoprost; Dinoprostone; Epidermal Growth Factor; Female; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Oxytocin; Placenta; Placenta Diseases; Platelet Activating Factor; Pregnancy; Thromboxane B2 | 1993 |
Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cell-Free System; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Quinolines; Rats; Structure-Activity Relationship; Subcellular Fractions | 1993 |
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.
Topics: Animals; Antibodies, Monoclonal; Edema; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Receptors, Very Late Antigen; Zymosan | 1993 |
Octreotide effectively decreases mucosal damage in experimental colitis.
Topics: Acetates; Acetic Acid; Animals; Colitis; Colon; Intestinal Mucosa; Leukotriene B4; Male; Octreotide; Platelet Activating Factor; Rats; SRS-A | 1993 |
Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils.
Topics: Adult; Chemotaxis, Leukocyte; Depression, Chemical; Dietary Fats, Unsaturated; Diglycerides; Fatty Acids; Fatty Acids, Omega-3; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Middle Aged; Monocytes; Neutrophils; Phosphatidylinositols; Platelet Activating Factor | 1993 |
Stimulation of human polymorphonuclear leukocytes by leukotriene B4 and platelet-activating factor: an ultrastructural and pharmacological study.
Topics: Acetylglucosaminidase; Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Ionomycin; Leukotriene B4; Lipoxygenase Inhibitors; Microscopy, Electron; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Quinolines | 1993 |
Migratory responses of ovine neutrophils to inflammatory mediators in vitro and in vivo.
Topics: Animals; Cell Movement; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Female; Interleukin-8; Leukotriene B4; Microscopy; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sheep; Skin; Spectrometry, Gamma | 1993 |
Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia.
Topics: Abetalipoproteinemia; Adult; Blood Platelets; Eicosanoids; Fatty Acids; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipoproteins, LDL; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1993 |
Are leukotrienes or PAF involved in hyperbaric oxygen toxicity?
Topics: Animals; Benzopyrans; Female; Furans; Indoles; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Oxygen; Platelet Activating Factor; Pressure; Propionates; Quinolines; Rats; Seizures; Specific Pathogen-Free Organisms; SRS-A | 1993 |
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
Topics: Arachidonic Acid; Calcimycin; Fatty Acids; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
Leukocyte-endothelial cell adhesion in spontaneously hypertensive and normotensive rats.
Topics: Animals; Arginine; Cell Adhesion; Endothelium, Vascular; Hypertension; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Nitroarginine; Platelet Activating Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Splanchnic Circulation; Stress, Mechanical | 1993 |
Energy-dependent export of leukotriene B4 in Xenopus oocytes.
Topics: Animals; Arachidonate Lipoxygenases; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Epoxide Hydrolases; Female; In Vitro Techniques; Leukotriene B4; Microinjections; Oocytes; Platelet Activating Factor; Tritium; Xenopus laevis | 1993 |
Hyporesponsiveness to inhibitory agents of alveolar macrophages and polymorphonuclear leukocytes primed by platelet activating factor.
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Cells, Cultured; Dexamethasone; Female; Humans; Leukotriene B4; Lymphocyte Activation; Macrophage Activation; Macrophages, Alveolar; Male; Middle Aged; Neutrophils; Phthalazines; Platelet Activating Factor; Superoxides | 1993 |
Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in cirrhosis.
Topics: Adult; Aged; Arachidonic Acid; Calcimycin; Female; Humans; Leukotriene B4; Liver Cirrhosis; Male; Mass Spectrometry; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1993 |
5-hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism.
Topics: Calcium; Cells, Cultured; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tumor Necrosis Factor-alpha | 1993 |
Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils.
Topics: Calcium; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-1; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Prostaglandin E2 limits arachidonic acid availability and inhibits leukotriene B4 synthesis in rat alveolar macrophages by a nonphospholipase A2 mechanism.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats | 1993 |
Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Azepines; Benzopyrans; Blood Pressure; Cell Adhesion; Cell Communication; Cell Movement; Leukocytes; Leukotriene B4; Mesenteric Veins; Microscopy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinacrine; Rats; Rats, Inbred WKY; Regional Blood Flow; Triazoles; Venules | 1993 |
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum.
Topics: Animals; Bacterial Toxins; Chemotaxis, Leukocyte; Endopeptidases; Enteritis; Enterotoxins; Ileal Diseases; Ileum; Intestinal Mucosa; Ketotifen; Leukotriene B4; Male; Mannitol; Mast Cells; Neutrophils; Permeability; Platelet Activating Factor; Rats; Rats, Wistar; SRS-A | 1993 |
Protective effects of PF-10040 in experimental NSAID-gastritis: role of leukocytes, leukotrienes and PAF.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Movement; Disease Models, Animal; Free Radical Scavengers; Gastric Acid; Gastric Mucosa; Gastritis; Isoquinolines; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Vasoconstriction | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan | 1995 |
KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils.
Topics: Acetyltransferases; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Autacoids; Dibenzoxepins; Enzyme Activation; Eosinophils; Guinea Pigs; Humans; Leukotriene B4; Lipids; Lipoxygenase Inhibitors; Male; Neutrophils; Olopatadine Hydrochloride; Platelet Activating Factor; Thromboxane B2; Thromboxane-A Synthase | 1996 |
Nasal neutrophilia and release of myeloperoxidase induced by nasal challenge with platelet activating factor: different degrees of responsiveness in atopic and nonatopic subjects.
Topics: Administration, Intranasal; Adult; Female; Humans; Hypersensitivity, Immediate; Leukocyte Count; Leukocytosis; Leukotriene B4; Male; Nasal Lavage Fluid; Neutrophils; Peroxidase; Platelet Activating Factor; Rhinitis, Allergic, Seasonal; Sodium Chloride | 1996 |
Microvascular mechanisms of histamine-induced potentiation of leukocyte adhesion evoked by chemoattractants.
Topics: Amino Acid Sequence; Animals; Azepines; Chemotactic Factors; Drug Synergism; Female; Histamine; Leukocytes; Leukotriene B4; Microcirculation; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Wistar; Splanchnic Circulation; Triazoles | 1995 |
Granulocytes from chronic myeloid leukemia (CML) patients show differential response to different chemoattractants.
Topics: Chemotactic Factors; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Reference Values | 1996 |
Priming of eosinophil recruitment in vivo by LPS pretreatment.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; CD18 Antigens; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cycloheximide; Drug Synergism; Edema; Eosinophilia; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Protein Synthesis Inhibitors; Pyrans; Quinolones; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Sialoglycoproteins; Skin; Triazoles; Zymosan | 1996 |
Nitrite/nitrate (NOX) and type II phospholipase A2, leukotriene B4, and platelet-activating factor levels in patients with septic shock.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Aged; Group II Phospholipases A2; Humans; Leukotriene B4; Middle Aged; Nitrates; Nitrites; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Shock, Septic | 1996 |
Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro.
Topics: Aluminum Hydroxide; Animals; Antigens; Bronchoalveolar Lavage Fluid; Calcimycin; Dextrans; Eosinophils; Gels; Guinea Pigs; Indicators and Reagents; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Ionophores; Leukocyte Count; Leukotriene B4; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Respiratory System; Superoxides; Thromboxane B2 | 1996 |
Microvascular dysfunction induced by nonsteroidal anti-inflammatory drugs: role of leukocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Capillary Permeability; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Endothelium, Vascular; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Time Factors; Venules | 1996 |
Bradykinin stimulates alveolar macrophages to release neutrophil, monocyte, and eosinophil chemotactic activity.
Topics: Animals; Asthma; Bradykinin; Bronchoalveolar Lavage Fluid; Cattle; Chemotactic Factors, Eosinophil; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Molecular Weight; Monocyte Chemoattractant Proteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4 | 1996 |
Leukotriene B4 and platelet activating factor production in permeabilized human neutrophils: role of cytosolic PLA2 in LTB4 and PAF generation.
Topics: Adenosine Triphosphate; Adult; Calcium; Cell Compartmentation; Cell Membrane Permeability; Coenzyme A; Cytosol; GTP-Binding Proteins; Humans; Inflammation Mediators; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Modulation of human neutrophil chemotaxis by the endothelin-B receptor agonist sarafotoxin S6c.
Topics: Calcium; Chemotaxis, Leukocyte; Cytoplasm; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Humans; Interleukin-8; Leukotriene B4; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Endothelin; Vasoconstrictor Agents; Viper Venoms | 1996 |
Selective inhibition of phosphodiesterase type IV suppresses the chemotactic responsiveness of rat eosinophils in vitro.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Eosinophils; Isoenzymes; Leukotriene B4; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1996 |
Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502.
Topics: Aluminum; Basophils; Calcimycin; Calcium; Depression, Chemical; Gene Expression Regulation; GTP-Binding Proteins; Humans; Interleukin-8; Ionophores; Leukocytes, Mononuclear; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines | 1996 |
Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism.
Topics: Animals; Diterpenes; Free Radicals; Ginkgolides; Indoles; Lactones; Leukotriene B4; Lipase; Male; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
[The inhibitory effect of LTB4 antagonist on eosinophil infiltration in cutaneous and gut late phase response in BALB/C mice sensitized with ovalubumin (OVA)].
Topics: Animals; Cell Movement; Dermatitis, Atopic; Eosinophils; Female; Immunization; Immunosuppressive Agents; Intestines; Leukotriene B4; Mice; Mice, Inbred BALB C; Ovalbumin; Phenylpropionates; Platelet Activating Factor; Skin; Thiazoles | 1997 |
PAF modulates eicosanoids and TNF release in immune-complex arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthus Reaction; Cattle; Dinoprostone; Eicosanoids; Indoles; Indomethacin; Injections, Intra-Articular; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Wistar; Synovial Fluid; Thromboxane B2; Tumor Necrosis Factor-alpha | 1997 |
Postural vasoregulation and mediators of reperfusion injury in venous ulceration.
Topics: Aged; Aged, 80 and over; Blood Pressure; Cytokines; Humans; Interleukin-1; Interleukin-6; Ischemia; Laser-Doppler Flowmetry; Leg; Leukotriene B4; Microcirculation; Middle Aged; P-Selectin; Platelet Activating Factor; Plethysmography, Impedance; Posture; Receptors, Interleukin-1; Regional Blood Flow; Reperfusion Injury; Thromboxane B2; Treatment Outcome; Tumor Necrosis Factor-alpha; Varicose Ulcer; Vasomotor System; Wound Healing | 1997 |
Endogenous fibronectin of blood polymorphonuclear leukocytes: stimulus-induced secretion and proteolysis by cell surface-bound elastase.
Topics: Antibodies, Monoclonal; Cell Adhesion Molecules; Cell Membrane; Chemotactic Factors; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibronectins; Flow Cytometry; Humans; Leukocyte Elastase; Leukotriene B4; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1997 |
Pertussis toxin shows distinct early signalling events in platelet-activating factor-, leukotriene B4-, and C5a-induced eosinophil homotypic aggregation in vitro and recruitment in vivo.
Topics: Animals; Calcium; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Enzyme Inhibitors; Eosinophils; Female; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoenzymes; Isoquinolines; Leukotriene B4; Pertussis Toxin; Phospholipase C beta; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Agonist-induced adherence of equine eosinophils to fibronectin.
Topics: Animals; Cell Adhesion; Complement C5a; Eosinophils; Female; Fibronectins; Horse Diseases; Horses; Humans; In Vitro Techniques; Interleukin-5; Leukotriene B4; Neutrophils; Platelet Activating Factor | 1997 |
Glucocorticoid receptor regulates expression of L-selectin and CD11/CD18 on human neutrophils.
Topics: CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Dexamethasone; Dinoprostone; Down-Regulation; Flow Cytometry; Glucocorticoids; Humans; In Vitro Techniques; Integrins; Intercellular Adhesion Molecule-1; L-Selectin; Leukotriene B4; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Glucocorticoid; Up-Regulation | 1997 |
Low-density lipoprotein receptor knockout mice exhibit exaggerated microvascular responses to inflammatory stimuli.
Topics: Animals; Cell Adhesion; Cell Movement; Inflammation; Leukocytes; Leukotriene B4; Mice; Mice, Knockout; Microcirculation; Muscle, Skeletal; Platelet Activating Factor; Receptors, LDL; Tumor Necrosis Factor-alpha | 1997 |
Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils.
Topics: Humans; Inflammation; Leukocyte Elastase; Leukotriene B4; Macrophage-1 Antigen; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Respiratory Burst; Superoxides; Wounds and Injuries | 1997 |
Effects of fluvastatin on leukocyte-endothelial cell adhesion in hypercholesterolemic rats.
Topics: Animals; Anticholesteremic Agents; Cell Adhesion; Cell Movement; Cholesterol, Dietary; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Pravastatin; Rats; Rats, Sprague-Dawley | 1997 |
Chemokine-induced eosinophil recruitment. Evidence of a role for endogenous eotaxin in an in vivo allergy model in mouse skin.
Topics: Anaphylaxis; Animals; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a; Cytokines; Eosinophils; Female; Hypersensitivity; Hypersensitivity, Delayed; Leukotriene B4; Mice; Mice, Inbred CBA; Platelet Activating Factor; Receptors, CCR3; Receptors, Chemokine; Skin | 1997 |
Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro.
Topics: Antibodies, Monoclonal; Antigens, CD; Apoptosis; Cells, Cultured; DNA Fragmentation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Kinetics; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phytic Acid; Platelet Activating Factor; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Recombinant Proteins; Signal Transduction; Tumor Necrosis Factor-alpha | 1997 |
Adenosine A3 receptor stimulation inhibits migration of human eosinophils.
Topics: Adenosine; CD18 Antigens; Chemokine CCL5; Chemotaxis, Leukocyte; Eosinophils; Humans; In Vitro Techniques; L-Selectin; Leukotriene B4; Macrophage-1 Antigen; Platelet Activating Factor; Receptor, Adenosine A3; Receptors, Purinergic P1 | 1997 |
Eosinophil chemotaxis induced by several biologically active substances and the effects of apafant on it in vitro.
Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Chemotaxis; Eosinophils; Guinea Pigs; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles | 1997 |
Regulation of leukotriene and platelet-activating factor synthesis in human alveolar macrophages.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Arachidonic Acids; Asthma; Benzenesulfonates; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Ionophores; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Urea | 1997 |
The proinflammatory cytokines and arachidonic acid metabolites in human overnight tears: homeostatic mechanisms.
Topics: Adult; Antibodies, Blocking; Arachidonic Acids; Blotting, Western; Cell Movement; Chemokine CCL2; Chemotaxis; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Homeostasis; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Leukocyte Count; Leukotriene B4; Neutrophils; Ocular Physiological Phenomena; Platelet Activating Factor; Receptors, Fc; Tears; Time Factors | 1998 |
Enhancement of leukotriene B4 release in stimulated asthmatic neutrophils by platelet activating factor.
Topics: Adult; Arachidonate 5-Lipoxygenase; Asthma; Calcimycin; Calcium; Cells, Cultured; Cytosol; Female; Humans; Ionophores; Leukotriene B4; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1997 |
Antihistaminic and antiallergic properties of dextro-mequitamium iodide in upper and lower guinea pig airways: comparison with azelastine.
Topics: Animals; Anti-Allergic Agents; Bronchi; Capillary Permeability; Cattle; Chemotaxis; Eosinophils; Guinea Pigs; Histamine H1 Antagonists; Insufflation; Leukotriene B4; Male; Phenothiazines; Phthalazines; Platelet Activating Factor; Rabbits; Rats; Vasoconstriction | 1998 |
Hepoxilin A3 inhibits agonist-evoked rise in free intracellular calcium in human neutrophils.
Topics: 8,11,14-Eicosatrienoic Acid; Calcium; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1997 |
Effect of GM-CSF on leukotriene B4 synthesis in human neutrophils: facilitation of the priming effect by autologous plasma.
Topics: Arachidonic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Neutrophils; Plasma; Platelet Activating Factor | 1997 |
Hypertonic saline activates lipid-primed human neutrophils for enhanced elastase release.
Topics: Humans; Leukotriene B4; Multiple Organ Failure; Multiple Trauma; Neutrophil Activation; Neutrophils; Osmolar Concentration; Pancreatic Elastase; Platelet Activating Factor; Resuscitation; Saline Solution, Hypertonic; Superoxides | 1998 |
The effect of salmeterol on human eosinophils is both stimulus- and response-dependent.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; beta-N-Acetylhexosaminidases; Cell Adhesion; Eosinophil Peroxidase; Eosinophils; Fibronectins; Humans; Interleukin-5; Leukotriene B4; Peroxidases; Platelet Activating Factor; Propanolamines; Salmeterol Xinafoate; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Synergistic effect of type II phospholipase A2 and platelet-activating factor on Mac-1 surface expression and exocytosis of gelatinase granules in human neutrophils: evidence for the 5-lipoxygenase-dependent mechanism.
Topics: Arachidonate 5-Lipoxygenase; Benzoquinones; Calcium; Cytoplasmic Granules; Dose-Response Relationship, Drug; Drug Synergism; Exocytosis; Gelatinases; Humans; Leukotriene B4; Macrophage-1 Antigen; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1998 |
Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity.
Topics: Acetylcholine; Animals; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cholinergic Antagonists; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukins; Leukotriene B4; Leukotriene C4; Leukotriene D4; Macrophages, Alveolar; Monocytes; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Substance P | 1998 |
Effect of serine proteinase inhibitors on intracellular free calcium rise in human polymorphonuclear leukocytes after stimulation with receptor agonists.
Topics: Adult; Calcium; Female; Humans; In Vitro Techniques; Intracellular Fluid; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylmethylsulfonyl Fluoride; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Trypsin Inhibitors | 1998 |
Platelet-activating factor increases leukotriene B4 release in stimulated alveolar macrophages from asthmatic patients.
Topics: Adult; Arachidonate 5-Lipoxygenase; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Cytosol; Female; Humans; Inflammation Mediators; Ionophores; Leukotriene B4; Macrophages, Alveolar; Male; Middle Aged; Osmolar Concentration; Platelet Activating Factor; Reference Values | 1998 |
Effect of dietary n-3 fatty acids on hypoxia-induced necrotizing enterocolitis in young mice. n-3 fatty acids alter platelet-activating factor and leukotriene B4 production in the intestine.
Topics: Animals; Dietary Fats; Enterocolitis, Pseudomembranous; Fatty Acids, Omega-3; Hypoxia; Intestinal Mucosa; Intestines; Leukotriene B4; Mice; Mice, Inbred BALB C; Platelet Activating Factor | 1998 |
Effect of selective phosphodiesterase inhibitors on the rat eosinophil chemotactic response in vitro.
Topics: Analysis of Variance; Animals; Cell Movement; Chemotactic Factors, Eosinophil; Cyclic AMP; Cyclic GMP; Eosinophils; Leukotriene B4; Phosphodiesterase Inhibitors; Platelet Activating Factor; Rats; Rats, Wistar | 1997 |
Cytokine and lipid inflammatory mediator profile of human tears during contact lens associated inflammatory diseases.
Topics: Acute Disease; Analysis of Variance; Cells, Cultured; Contact Lenses; Corneal Ulcer; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation Mediators; Interleukin-8; Keratitis; Leukotriene B4; Lipids; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Fc; Tears | 1998 |
A CD18/ICAM-1-dependent pathway mediates eosinophil adhesion to human bronchial epithelial cells.
Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Chemokine CCL11; Chemokine CCL4; Chemokine CCL5; Chemokines, CC; Complement C5a; Cytokines; Eosinophils; Epithelial Cells; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Kinetics; Leukotriene B4; Lung; Macrophage Inflammatory Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Inhibition by the anti-mitotic drug doxorubicin of platelet-activating-factor-induced late eosinophil accumulation in rats.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Division; Doxorubicin; Eosinophils; Female; Leukotriene B4; Male; Platelet Activating Factor; Pleura; Rats; Rats, Wistar | 1998 |
Effects of lipid mediators on the synthesis of leukaemia inhibitory factor and interleukin 6 by human bone marrow stromal cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Bone Marrow Cells; Cells, Cultured; Culture Media, Serum-Free; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Growth Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Interleukin-6; Leukemia Inhibitory Factor; Leukotriene B4; Lipids; Lymphokines; Platelet Activating Factor; Stromal Cells; Tumor Necrosis Factor-alpha | 1998 |
Release of granule proteins from human eosinophils stimulated with mast-cell mediators.
Topics: Blood Proteins; Calcium; Chemotactic Factors, Eosinophil; Cytokines; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Histamine; Humans; Inflammation Mediators; Kinetics; Leukotriene B4; Leukotriene C4; Mast Cells; Platelet Activating Factor; Prostaglandin D2; Ribonucleases | 1998 |
Sulochrin inhibits eosinophil activation and chemotaxis.
Topics: Animals; Anti-Allergic Agents; Benzoates; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Humans; Immunoglobulin A; Immunoglobulin G; Interleukin-8; Leukotriene B4; Leukotriene C4; Platelet Activating Factor; Sepharose; Superoxides | 1998 |
Bradykinin stimulates type II alveolar cells to release neutrophil and monocyte chemotactic activity and inflammatory cytokines.
Topics: Antibodies; Bradykinin; Bradykinin Receptor Antagonists; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemotactic Factors; Culture Media, Conditioned; Cycloheximide; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Isoquinolines; Leukotriene B4; Lipoxygenase Inhibitors; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Alveoli; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Tetrahydroisoquinolines; Transforming Growth Factor beta | 1998 |
Smoke extract stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activity.
Topics: Antibodies; Cells, Cultured; Chromatography, Gel; Cytokines; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Monocyte Chemoattractant Proteins; Nicotiana; Plants, Toxic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Smoke; Time Factors | 1998 |
5-oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of L-selectin shedding, surface expression of CD11b, actin polymerization, and calcium mobilization in human eosinophils.
Topics: Actins; Arachidonic Acids; Calcium; Chemotactic Factors; Enzyme Inhibitors; Eosinophils; Humans; Kinetics; L-Selectin; Leukotriene B4; Macrophage-1 Antigen; Platelet Activating Factor; Polymers; Protein Kinase Inhibitors | 1999 |
Increased gastric production of platelet-activating factor, leukotriene-B4, and tumor necrosis factor-alpha in children with Helicobacter pylori infection.
Topics: Case-Control Studies; Child; Chromatography, High Pressure Liquid; Female; Gastric Juice; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Leukotriene B4; Male; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1999 |
Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation?
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cytokines; Dinoprostone; Extracorporeal Circulation; Humans; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Interleukin-8; Leukotriene B4; Leukotriene C4; Lipid Metabolism; Lipids; Multiple Organ Failure; Platelet Activating Factor; Prospective Studies; Thromboxane B2; Tumor Necrosis Factor-alpha | 1999 |
Inhibition by leukotriene inhibitors, and calcium and platelet-activating factor antagonists, of acute gastric and intestinal damage in arthritic rats and in cholinomimetic-treated mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arthritis; Arthritis, Experimental; Calcium; Cholinergic Agents; Female; Leukotriene Antagonists; Leukotriene B4; Male; Mice; Peptic Ulcer; Platelet Activating Factor; Rats; Thiocholine | 1999 |
Reperfusion-induced oxidative stress in diabetes: cellular and enzymatic sources.
Topics: Animals; Antibodies, Monoclonal; Diabetes Mellitus, Experimental; Free Radicals; Intercellular Adhesion Molecule-1; Leukotriene B4; Male; Monocytes; Neutrophils; Oxidative Stress; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Streptozocin; Superoxide Dismutase; Xanthine Oxidase | 1999 |
Impaired mesenteric leukocyte recruitment in experimental portal hypertension in the rat.
Topics: Animals; Cell Movement; Hypertension, Portal; Leukocytes; Leukotriene B4; Macrophage-1 Antigen; Male; Mesentery; P-Selectin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1999 |
VCAM-1 contributes to rapid eosinophil accumulation induced by the chemoattractants PAF and LTB4: evidence for basal expression of functional VCAM-1 in rat skin.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Chemotaxis, Leukocyte; Dactinomycin; Edema; Eosinophils; Immunoenzyme Techniques; Integrin alpha4; Integrins; Leukotriene B4; Male; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Skin; Skin Diseases; Vascular Cell Adhesion Molecule-1 | 1999 |
Effect of inflammatory mediators on the electrophysiology of the human oviduct.
Topics: Alprostadil; Calcium; Cells, Cultured; Chlorides; Dinoprostone; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Ion Channels; Leukotriene B4; Membrane Potentials; Piperidines; Platelet Activating Factor | 1999 |
Regulation of oscillations in filamentous actin content in polymorphonuclear leukocytes stimulated with leukotriene B(4) and platelet-activating factor.
Topics: Actins; Cell Compartmentation; Gelsolin; Humans; Leukotriene B4; Myosin Light Chains; Myosins; Neutrophils; Periodicity; Phosphorylation; Platelet Activating Factor; Protein Binding; Protein Kinase C; Serine | 1999 |
Eosinophils isolated by magnetic cell sorting respond poorly to lipid chemoattractants.
Topics: Blood Donors; Chemotactic Factors; Chemotaxis; Dose-Response Relationship, Drug; Endothelium, Vascular; Eosinophils; Humans; Immunomagnetic Separation; Leukotriene B4; Platelet Activating Factor; Povidone; Silicon Dioxide; Umbilical Veins | 1999 |
The potential of various lipopolysaccharides to release monocyte chemotactic activity from lung epithelial cells and fibroblasts.
Topics: Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Cycloheximide; Epithelial Cells; Escherichia coli; Fibroblasts; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Lung; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymyxin B; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1999 |
Interactions between neutrophil gelatinase-associated lipocalin and natural lipophilic ligands.
Topics: Acute-Phase Proteins; Carrier Proteins; Chromatography, Affinity; Chromatography, Liquid; Enzyme Inhibitors; Gelatinases; Humans; Leukotriene B4; Ligands; Lipocalin-2; Lipocalins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oncogene Proteins; Platelet Activating Factor; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence | 1999 |
Modulation of C5a-mediated effector functions of human polymorphonuclear leukocytes by tumor necrosis factor alpha and granulocyte macrophage colony-stimulating factor.
Topics: CD18 Antigens; Cell Adhesion Molecules; Cell Degranulation; Chemotaxis, Leukocyte; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-8; Leukotriene B4; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Radioligand Assay; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice.
Topics: Acute Disease; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Movement; Crosses, Genetic; Cysteine; Dermatitis, Contact; Ear; Epoxide Hydrolases; Fluorescein-5-isothiocyanate; Immunoglobulin E; Inflammation Mediators; Leukotriene B4; Leukotrienes; Lipopolysaccharides; Mice; Mice, Knockout; Neutrophils; Peritonitis; Platelet Activating Factor | 1999 |
Inhaled NO reaches distal vasculatures to inhibit endothelium- but not leukocyte-dependent cell adhesion.
Topics: Administration, Inhalation; Animals; Capillary Permeability; Cats; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Hydrogen Peroxide; Leukocytes; Leukotriene B4; Lung; Microscopy, Video; Nitric Oxide; Oxadiazoles; Oxidants; Oxidative Stress; P-Selectin; Platelet Activating Factor; Quinoxalines | 1999 |
Inhibition of cytosolic phospholipase A(2) attenuates activation of mitogen-activated protein kinases in human monocytic cells.
Topics: Arachidonic Acid; CCAAT-Enhancer-Binding Proteins; Cell Line; Cytosol; DNA-Binding Proteins; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Leukotriene B4; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Nuclear Proteins; Oligonucleotides, Antisense; Phospholipases A; Phosphorylation; Platelet Activating Factor; STAT1 Transcription Factor; Trans-Activators; Transcription Factor AP-1 | 2000 |
Levels of leukotriene B4 and platelet activating factor in gingival crevicular fluid in renal transplant patients receiving cyclosporine A.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cyclosporine; Dental Plaque Index; Female; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingival Hyperplasia; Gingival Overgrowth; Gingivitis; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukotriene B4; Male; Periodontium; Platelet Activating Factor; Radioimmunoassay | 2000 |
The potential of various lipopolysaccharides to release IL-8 and G-CSF.
Topics: Antibodies; Cell Line; Escherichia coli; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Osmolar Concentration; Platelet Activating Factor; Polymyxin B; Pseudomonas aeruginosa; Receptors, Leukotriene B4 | 2000 |
Mechanisms of Helicobacter pylori-induced rat gastric mucosal microcirculatory disturbances in vivo.
Topics: Animals; Arginine; Blood Platelets; Dinoprostone; Gastric Mucosa; Helicobacter pylori; Histamine H1 Antagonists; Ketotifen; Leukocytes; Leukotriene B4; Male; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serum Albumin; Thromboxane A2 | 2000 |
Effects of the platelet activating factor antagonists BN 52021 and BN 50730 on antigen-induced bronchial hyperresponsiveness and eosinophil infiltration in lung from sensitized guinea-pigs.
Topics: Acetylcholine; Aerosols; Animals; Azepines; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Diterpenes; Eosinophilia; Ginkgo biloba; Ginkgolides; Guinea Pigs; Lactones; Leukotriene B4; Lung Diseases; Male; Molecular Structure; Ovalbumin; Plants, Medicinal; Platelet Activating Factor; Specific Pathogen-Free Organisms; Thienopyridines; Triazoles | 1993 |
Major trauma enhances store-operated calcium influx in human neutrophils.
Topics: Adult; Calcium; Complement C5a; Female; Humans; In Vitro Techniques; Interleukin-8; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Spectrophotometry; Wounds and Injuries | 2000 |
Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Bone Marrow Cells; Cells, Cultured; Cytokines; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Leukotriene B4; Lipid Metabolism; Lipoxins; Platelet Activating Factor; Stromal Cells | 2000 |
E. coli hemolysin-induced lipid mediator metabolism in alveolar macrophages: impact of eicosapentaenoic acid.
Topics: Animals; Eicosanoids; Eicosapentaenoic Acid; Escherichia coli; Hemolysin Proteins; Hydroxyeicosatetraenoic Acids; Inflammation Mediators; Leukotriene B4; Lipid Metabolism; Lipoxygenase Inhibitors; Macrophages, Alveolar; Platelet Activating Factor; Rabbits | 2000 |
Mediation by platelet-activating factor of 12-hydroxyeicosatetraenoic acid-induced cytosolic free calcium concentration elevation in neutrophils.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Azepines; Calcium; Cytosol; Enzyme Inhibitors; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rabbits; Terpenes; Tosylphenylalanyl Chloromethyl Ketone; Triazoles | 2000 |
Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bronchi; Cell Line, Transformed; Chemotactic Factors; Dinoprostone; Epithelial Cells; Gene Expression; HeLa Cells; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-6; Leukotriene B4; Platelet Activating Factor; Pneumonia; Respiratory Mucosa; RNA, Messenger | 2001 |
Dissipative metabolic patterns respond during neutrophil transmembrane signaling.
Topics: Antigen-Antibody Complex; Chemotaxis, Leukocyte; Humans; Interferon-gamma; Interleukin-6; Interleukin-8; Leukotriene B4; Ligands; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Platelet Activating Factor; Signal Transduction; Spectrometry, Fluorescence | 2001 |
Role of petasin in the potential anti-inflammatory activity of a plant extract of petasites hybridus.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asteraceae; Calcium; Complement C5a; Cysteine; Eosinophils; Humans; Hydroxyurea; In Vitro Techniques; Leukotriene B4; Leukotrienes; Macrophages; Neutrophils; Plant Extracts; Platelet Activating Factor; Sesquiterpenes; Signal Transduction | 2001 |
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep | 2001 |
BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Carcinogens; Chlorobenzenes; Dinoprostone; Dose-Response Relationship, Drug; Erythema; Female; Guinea Pigs; Humans; Inflammation; Leukotriene B4; Male; Mice; Neutrophils; Phorbol Esters; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Skin; Sulfones | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Activation-induced mobilization of secretory vesicles in bovine neutrophils.
Topics: Alkaline Phosphatase; Animals; Cattle; Inflammation Mediators; Interleukin-8; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Platelet Activating Factor; Secretory Vesicles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Activated polymorphonuclear cells increase sickle red blood cell retention in lung: role of phospholipids.
Topics: Anemia, Sickle Cell; Animals; Cell Adhesion; Chromium Radioisotopes; Erythrocytes; Humans; In Vitro Techniques; Leukotriene B4; Male; NADPH Oxidases; Neutrophils; Perfusion; Phospholipids; Platelet Activating Factor; Positive-Pressure Respiration; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tidal Volume | 2002 |
Novel action of lignans isolated from Hernandia nymphaeifolia on Ca2+ signaling in human neutrophils.
Topics: Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fluorescent Dyes; Fura-2; Humans; Leukotriene B4; Lignans; Magnoliopsida; Neutrophils; Platelet Activating Factor; Thapsigargin | 2002 |
Sephadex induces eosinophil migration to the rat and mouse peritoneal cavity: involvement of mast cells, LTB4, TNF-alpha, IL-8 and PAF.
Topics: Animals; Cell Movement; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukotriene B4; Male; Mast Cells; Mice; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2002 |
Leukotriene B(4) induces nitric oxide synthesis in Trypanosoma cruzi-infected murine macrophages and mediates resistance to infection.
Topics: Animals; Benzopyrans; Carboxylic Acids; Cells, Cultured; Chagas Disease; Disease Models, Animal; Female; Immunity, Innate; Interferon-gamma; Leukotriene B4; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Platelet Activating Factor; Receptors, Leukotriene B4; Time Factors; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2002 |
Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.
Topics: Acyltransferases; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ionophores; Leukotriene B4; Leukotrienes; Lipid Metabolism; Lipoxygenase Inhibitors; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor | 2002 |
Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.
Topics: Arachidonic Acid; Autocrine Communication; Azepines; Escherichia coli; Humans; In Vitro Techniques; Indoles; Interleukin-10; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipopolysaccharide Receptors; Lipopolysaccharides; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prospective Studies; Respiratory Burst; Superoxides; Triazoles | 2002 |
The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the generation of platelet-activating factor and leukotriene B4 in hypoxic-ischemic brain in young mice.
Topics: Animals; Brain; Dietary Supplements; Fatty Acids, Omega-3; Female; Hypoxia-Ischemia, Brain; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Time Factors | 2002 |
A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligaton and puncture sepsis.
Topics: Animals; Cecum; Cell Movement; Dihydropyridines; Eicosanoids; Imidazoles; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peritoneum; Platelet Activating Factor; Prostaglandins; Time Factors; Wounds, Penetrating | 2003 |
Mesenteric microvascular inflammatory responses to systemic hypoxia are mediated by PAF and LTB4.
Topics: Animals; Azepines; Capillary Permeability; Cell Adhesion; Fluorescence; Hypoxia; Leukocytes; Leukotriene B4; Male; Microcirculation; Oxidants; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Rhodamines; Splanchnic Circulation; Triazoles; Vasculitis | 2003 |
Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants.
Topics: Animals; Antioxidants; Cell Adhesion; Flavonoids; Free Radicals; Hypoxanthine; Inflammation; Leukocytes; Leukotriene B4; Male; Oxidants; Phenols; Platelet Activating Factor; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Time Factors; Xanthine Oxidase | 2003 |
Inhibitory effects of glucocorticoids on rat eosinophil superoxide generation and chemotaxis.
Topics: Animals; Beclomethasone; Cells, Cultured; Chemotaxis, Leukocyte; Dexamethasone; Eosinophils; Glucocorticoids; In Vitro Techniques; Leukocyte Count; Leukotriene B4; Male; Mometasone Furoate; Platelet Activating Factor; Pregnadienediols; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Experimental Trypanosoma cruzi infection in platelet-activating factor receptor-deficient mice.
Topics: Animals; Antibodies, Protozoan; Cells, Cultured; Chagas Cardiomyopathy; Chemokine CCL2; Chemokine CCL5; Female; Heart; Immunoglobulin M; Interferon-gamma; Leukotriene B4; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nitric Oxide; Parasitemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Trypanosoma cruzi; Tumor Necrosis Factor-alpha | 2003 |
Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Leukotriene B4; Lipoxygenase Inhibitors; Platelet Activating Factor; Pyrans; Structure-Activity Relationship | 2003 |
Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2.
Topics: Air Pollutants; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Chromatography, Thin Layer; Dinoprostone; Dogs; Enzyme Activation; Fatty Acids, Unsaturated; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophages, Alveolar; Phospholipases A; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sulfates; Sulfites; Sulfur; Thromboxane B2 | 2003 |
A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation.
Topics: Acute Disease; Animals; Arachidonic Acid; Carrageenan; Cells, Cultured; Convalescence; Corticosterone; Cyclooxygenase 2; Disease Progression; Enzyme Induction; Epithelial Cells; Fibroblasts; Group II Phospholipases A2; Group IV Phospholipases A2; Group V Phospholipases A2; Group VI Phospholipases A2; Interleukin-1; Isoenzymes; Leukotriene B4; Lipoxins; Macrophages; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2004 |
Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.
Topics: Actins; ADP Ribose Transferases; Amides; Anaphylatoxins; Androstadienes; Botulinum Toxins; Chemotactic Factors; Chemotaxis; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pseudopodia; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Wortmannin | 2004 |
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activ
Topics: Animals; Arachidonic Acid; Bronchoalveolar Lavage Fluid; CD11b Antigen; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Group IV Phospholipases A2; Humans; Inflammation; Ionomycin; Leukotriene B4; Mice; Mice, Transgenic; NADPH Oxidases; Neutrophils; Oxygen; Phagocytosis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pneumonia; Pyrrolidines; Receptors, IgG; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Effects of combined systemic administration of low-dose doxycycline and alendronate on endotoxin-induced periodontitis in rats.
Topics: Alendronate; Alveolar Bone Loss; Animals; Anti-Bacterial Agents; Dinoprost; Dinoprostone; Doxycycline; Drug Therapy, Combination; Endotoxins; Gingiva; Leukotriene B4; Male; Periodontitis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 2004 |
Therapeutic versus prophylactic plus therapeutic administration of omega-3 fatty acid on endotoxin-induced periodontitis in rats.
Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Dinoprost; Dinoprostone; Endotoxins; Fatty Acids, Omega-3; Gingiva; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene B4; Male; Periodontitis; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2004 |
CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism.
Topics: Actins; Animals; Chemokine CXCL9; Chemokines, CXC; Chemotaxis; Eosinophils; Female; In Vitro Techniques; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Transgenic; Platelet Activating Factor; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Receptors, CCR3; Receptors, Chemokine; Signal Transduction | 2005 |
Individual and combined effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on endotoxin-induced periodontitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Endotoxins; Fatty Acids, Omega-3; Leukotriene B4; Male; Periodontitis; Platelet Activating Factor; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Eosinophil trans-basement membrane migration induced by interleukin-8 and neutrophils.
Topics: Adult; Antibodies, Monoclonal; Asthma; Azepines; Basement Membrane; Chemotaxis, Leukocyte; Coculture Techniques; Collagen; Culture Media, Conditioned; Drug Combinations; Eosinophils; Humans; Interleukin-8; Laminin; Leukotriene B4; Matrix Metalloproteinase 9; Neutrophil Activation; Neutrophils; Paracrine Communication; Platelet Activating Factor; Protease Inhibitors; Proteoglycans; Pulmonary Eosinophilia; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Characterization of an activation factor released from human neutrophils after stimulation by triclinic monosodium urate crystals.
Topics: Calcium; Chemotaxis, Leukocyte; Crystallization; Humans; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Receptors, Formyl Peptide; Tyrosine; Uric Acid | 2006 |
The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis.
Topics: Dinoprostone; Humans; Imidazoles; Inflammation Mediators; Leukotriene B4; Neutrophils; Platelet Activating Factor; RNA Viruses; Signal Transduction; Toll-Like Receptor 7; Toll-Like Receptor 8 | 2007 |
Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice.
Topics: Animals; Basement Membrane; Bone Marrow Cells; Cell Movement; Chemotaxis, Leukocyte; Enzyme Inhibitors; Glycine; Leukocyte Elastase; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neutrophils; Platelet Activating Factor; Sulfonamides; Venules | 2007 |
Dietary ganglioside inhibits acute inflammatory signals in intestinal mucosa and blood induced by systemic inflammation of Escherichia coli lipopolysaccharide.
Topics: Animals; Cholesterol; Dietary Fats; Dinoprostone; Gangliosides; Inflammation; Interleukin-1beta; Intestinal Mucosa; Leukotriene B4; Lipopolysaccharides; Male; Membrane Microdomains; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
Itraconazole-mediated inhibition of calcium entry into platelet-activating factor-stimulated human neutrophils is due to interference with production of leukotriene B4.
Topics: Adenosine Triphosphate; Antifungal Agents; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Humans; Indoles; Itraconazole; Leukotriene Antagonists; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Spectrometry, Fluorescence; Tetrazoles | 2007 |
Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant.
Topics: Actins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Interleukin-8; Leukotriene B4; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Serine; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats.
Topics: Animals; Benzopyrans; Carboxylic Acids; Dermatitis; Dihydropyridines; Imidazoles; Leukotriene B4; Male; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Skin; Thiazoles | 2008 |
Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure.
Topics: Anti-Inflammatory Agents; Antifungal Agents; Cells, Cultured; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Leukotriene B4; Molecular Structure; Neutrophils; Platelet Activating Factor; Pyrimidines; Triazoles; Voriconazole | 2008 |
The effect of lidocaine on in vitro adhesion and migration of equine neutrophils.
Topics: Anesthetics, Local; Animals; Cell Adhesion; Cell Movement; Horses; Interleukin-8; Leukotriene B4; Lidocaine; Neutrophil Activation; Neutrophils; Platelet Activating Factor | 2009 |
Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation.
Topics: Adult; Anti-Inflammatory Agents; Calcium; Humans; Immunoassay; Immunologic Factors; Leukotriene B4; Neutrophils; Platelet Activating Factor; Spectrometry, Fluorescence; Triazoles; Young Adult | 2009 |
Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor.
Topics: Animals; Azepines; Cell Movement; Dihydropyridines; Female; Flagellin; Humans; Imidazoles; Leukotriene B4; Ligands; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Poly I-C; Propionates; Quinolines; Thienopyridines; Toll-Like Receptors; Triazoles | 2010 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Leukotriene B4; Male; Mast Cells; Ovalbumin; Peritoneal Cavity; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 2010 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
Discrimination between receptor- and store-operated Ca(2+) influx in human neutrophils.
Topics: Boron Compounds; Calcium; Humans; Immunologic Factors; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Calcium-Sensing; Spectrometry, Fluorescence; Strontium | 2010 |
CXCL8 attenuates chemoattractant-induced equine neutrophil migration.
Topics: Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Chemotactic Factors; Colforsin; Cyclic AMP; Horses; Interleukin-8; Leukotriene B4; Neutrophils; Platelet Activating Factor | 2011 |
2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52)--a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Caprylates; Carrageenan; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Neutrophils; Nuclear Envelope; Platelet Activating Factor; Pleurisy; Protein Transport; Pyrimidines; Rats; Rats, Wistar; Shock | 2011 |
Regulation of coronary venular barrier function by blood borne inflammatory mediators and pharmacological tools: insights from novel microvascular wall models.
Topics: Actins; Arterioles; Blood Platelets; Blood Proteins; Capillaries; Capillary Permeability; Cells, Cultured; Coronary Circulation; Dinoprostone; Drug Synergism; Endothelial Cells; Erythrocytes; Hemostatics; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Leukotriene B4; Myocarditis; Pericytes; Platelet Activating Factor; Thrombin; Venules | 2012 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
Systematic single cell analysis of migration and morphological changes of human neutrophils over stimulus concentration gradients.
Topics: Adult; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Leukotriene B4; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Primary Cell Culture; Single-Cell Analysis | 2014 |
Cooperative role of endogenous leucotrienes and platelet-activating factor in ischaemia-reperfusion-mediated tissue injury.
Topics: Amidines; Animals; Azepines; Biological Assay; Carbamates; Dermis; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Extremities; Inflammation; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Propionates; Quinolines; Rabbits; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Reperfusion Injury; Triazoles | 2013 |
Glutamine Prevents Late-Phase Anaphylaxis via MAPK Phosphatase 1-Dependent Cytosolic Phospholipase A2 Deactivation.
Topics: Anaphylaxis; Animals; Disease Models, Animal; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glutamine; Leukotriene B4; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Phosphorylation; Platelet Activating Factor; RNA, Small Interfering | 2016 |