1-hexadecyl-2-acetyl-glycero-3-phosphocholine and l 659989

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with l 659989 in 37 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (l 659989)	Trials (l 659989)	Recent Studies (post-2010) (l 659989)
9,156	187	552	40	0	0

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (18.92)	18.7374
1990's	30 (81.08)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
McIntyre, TM; Patel, KD; Prescott, SM; Zimmerman, GA	1
Bethel, RA; Tan, WC	1
Altavilla, D; Bussolino, F; Campo, GM; Caputi, AP; Ioculano, M; Squadrito, F; Zingarelli, B	1
Mustoe, TA; Porras-Reyes, BH	1
McIntyre, TM; Prescott, SM; Smiley, PL; Stremler, KE; Zimmerman, GA	1
Bertani, T; Boccardo, P; Macconi, D; Morigi, M; Remuzzi, G; Riccardi, E; Zilio, P	1
Cochrane, CG; Prossnitz, ER; Ye, RD; Zou, AH	1
Hwang, SB; Lam, MH	1
Alberts, A; Doebber, TW; Mauriello, A; Wu, MS	1
Hoffman, DR; Hwang, SB; Johnston, JM; Miyaura, S; Zhu, YP	1
Klahr, S; Reyes, AA	1
Buckalew, VM; Handa, RK; Strandhoy, JW	1
Arison, BH; Bugianesi, RL; Chabala, JC; Chang, MN; Hucker, HB; Ponpipom, MM; Sweeney, BM; Thomson, KL; White, SD	1
Baldi, E; Dunn, MJ; Emancipator, SN; Hassan, MO	1
Evans, RD; Ilic, V; Williamson, DH	1
Conklyn, M; Showell, HJ; Watson, JW	1
Hsu, AH; Hwang, SB; Lam, MH	1
Hsueh, W; Needleman, P; Spaethe, SM	1
Ng, DS; Wong, K	2
Acton, JJ; Alberts, AW; Biftu, T; Brooker, DR; Bugianesi, RL; Chabala, JC; Doebber, TW; Gamble, NL; Hwang, SB; Ponpipom, MM	1
Alberts, AW; Bugianesi, RL; Chabala, JC; Hwang, SB; Lam, MH; Ponpipom, MM	1
Chang, SW; Haynes, J; Morris, KG; Voelkel, NF	1
Altavilla, D; Bussolino, F; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Sardella, A; Squadrito, F; Urna, G	1
Baldi, E; Bonaccorsi, L; Carloni, V; Finetti, G; Forti, G; Laffi, G; Maggi, M; Muratori, M; Serio, M	1
Cundell, DR; Gerard, C; Gerard, NP; Idanpaan-Heikkila, I; Tuomanen, EI	1
Kleeberger, SR; Longphre, M	1
Aepfelbacher, M; Haag, H; Weber, C; Weber, PC; Ziegler-Heitbrock, HW	1
Conger, JD; Falk, SA; Lanese, DM	1
Hawes, AS; Isom, OW; Ko, W; Krieger, KH; Lang, D; Zelano, JA	1
Denning, GM; Hunninghake, GW; Kasner, NA; Stoll, LL	1
Fiorini, R; Giorgi, PL; Kantar, A	1
Jamieson, D; Lin, Y	1
Foppolo, M; Gallego, MJ; Imberti, B; Micheletti, G; Morigi, M; Remuzzi, A; Remuzzi, G; Zoja, C	1
Herbertson, MJ; Walley, KR; Werner, HA	1
Kerrigan, CL; Stotland, MA	1
Birk-Sørensen, L; Kerrigan, CL; Wang, C	1

Reviews

1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and l 659989

Article	Year
L-659,989: a useful probe in the detection of multiple conformational states of PAF receptors. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Binding, Competitive; Blood Platelets; Cell Membrane; Furans; Humans; Kinetics; Models, Biological; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Conformation; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1991

Other Studies

36 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and l 659989

Article	Year
Novel leukocyte agonists are released by endothelial cells exposed to peroxide. The Journal of biological chemistry, 1992, Jul-25, Volume: 267, Issue:21 Topics: Cell Adhesion; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Endothelium, Vascular; Furans; Humans; Isoflurophate; Neutrophils; Peroxides; Phospholipases A; Phospholipases A1; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; tert-Butylhydroperoxide; Type C Phospholipases; Up-Regulation	1992
The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs. The American review of respiratory disease, 1992, Volume: 146, Issue:4 Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Eosinophils; Furans; Guinea Pigs; Male; Methacholine Chloride; Ozone; Platelet Activating Factor; Respiratory Function Tests	1992
Platelet activating factor interaction with tumor necrosis factor and myocardial depressant factor in splanchnic artery occlusion shock. European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1 Topics: Anesthesia; Animals; Blood Pressure; Furans; Leukocyte Count; Macrophages; Male; Mice; Myocardial Depressant Factor; Phagocytosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock; Splanchnic Circulation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1992
Platelet-activating factor: improvement in wound healing by a chemotactic factor. Surgery, 1992, Volume: 111, Issue:4 Topics: Animals; Blood Pressure; Body Weight; Female; Furans; Heart Rate; Immunoenzyme Techniques; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Sex Characteristics; Time Factors; Wound Healing; Wounds and Injuries	1992
Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17 Topics: Azepines; Cell Adhesion; Furans; Humans; Hydrolysis; In Vitro Techniques; Indicators and Reagents; Kinetics; Neutrophils; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles	1991
Platelet-activating factor receptor blocking reduces proteinuria and improves survival in lupus autoimmune mice. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2 Topics: Animals; Blood Urea Nitrogen; Female; Furans; Kidney; Lupus Nephritis; Mice; Mice, Inbred NZB; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteinuria; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Survival Rate	1991
Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. Biochemical and biophysical research communications, 1991, Oct-15, Volume: 180, Issue:1 Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; Furans; Humans; Molecular Sequence Data; Oligonucleotide Probes; Open Reading Frames; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Transfection	1991
Platelet-activating factor (PAF) stimulates the lysoPAF acetyltransferase in leukocyte-rich plasma: use in PAF antagonist studies. Lipids, 1991, Volume: 26, Issue:12 Topics: Acetyltransferases; Animals; Enzyme Activation; Furans; Humans; Kinetics; Leukocytes; Macaca mulatta; Neutrophils; Pan troglodytes; Platelet Activating Factor; Rats; Reference Values	1991
Prolongation of parturition in the pregnant rat following treatment with a platelet activating factor receptor antagonist. Biology of reproduction, 1991, Volume: 44, Issue:1 Topics: Animals; Female; Furans; Gestational Age; Labor, Obstetric; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Time Factors	1991
Role of platelet-activating factor in renal function in normal rats and rats with bilateral ureteral obstruction. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 198, Issue:1 Topics: Animals; Female; Furans; Glomerular Filtration Rate; Kidney; Methacrylates; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains; Renal Circulation; Thromboxane A2; Thromboxane-A Synthase; Ureteral Obstruction	1991
Selective inhibition of vasoconstrictor responses by platelet-activating factor in rat kidney. The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 2 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcium Channel Blockers; Dopamine Antagonists; Dose-Response Relationship, Drug; Furans; Gallic Acid; Haloperidol; Hematocrit; Male; Nimodipine; Platelet Activating Factor; Potassium Chloride; Rats; Rats, Inbred Strains; Renal Circulation; Vasoconstriction	1991
Metabolism of the platelet-activating factor antagonist (+/-)-trans-2-(3'-methoxy-5'-methylsulphonyl-4'-propoxyphenyl)-5-(3",4" ,5"- trimethoxyphenyl)tetrahydrofuran (L-659,989) in rhesus monkeys. Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:5 Topics: Animals; Biological Availability; Biotransformation; Female; Furans; Isomerism; Macaca mulatta; Male; Platelet Activating Factor; Sex Factors; Tritium	1991
Platelet activating factor receptor blockade ameliorates murine systemic lupus erythematosus. Kidney international, 1990, Volume: 38, Issue:6 Topics: Animals; Female; Furans; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1990
Metabolic effects of platelet-activating factor in rats in vivo. Stimulation of hepatic glycogenolysis and lipogenesis. The Biochemical journal, 1990, Jul-01, Volume: 269, Issue:1 Topics: Animals; Blood Glucose; Female; Furans; Glycogen; Indomethacin; Insulin; Lipids; Liver; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triglycerides	1990
IgG1-mediated acute pulmonary hypersensitivity response in the guinea pig. Involvement of specific lipid mediators. The American review of respiratory disease, 1990, Volume: 142, Issue:5 Topics: Acute Disease; Animals; Azepines; Bronchoconstriction; Dicarboxylic Acids; Dose-Response Relationship, Drug; Furans; Guinea Pigs; Immunization; Immunoglobulin G; Indoles; Lipids; Lung; Male; Ovalbumin; Phenylcarbamates; Piroxicam; Platelet Activating Factor; Propranolol; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Sulfonamides; Tosyl Compounds; Triazoles	1990
Characterization of platelet-activating factor (PAF) receptor by specific binding of [3H]L-659,989, a PAF receptor antagonist, to rabbit platelet membranes: possible multiple conformational states of a single type of PAF receptors. Molecular pharmacology, 1989, Volume: 35, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Blood Platelets; Furans; Guanosine Triphosphate; In Vitro Techniques; Magnesium; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Conformation; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sodium	1989
Pharmacological manipulation of inflammation in rabbit hydronephrosis: effects of a combined cyclooxygenase/lipoxygenase inhibitor ethoxyquin, a thromboxane synthase inhibitor RS-5186 and a PAF antagonist L-659,989. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Ethoxyquin; Fatty Acids, Nonesterified; Furans; Hydronephrosis; Inflammation; Kidney; Leukotriene B4; Lipoxygenase Inhibitors; Male; Perfusion; Platelet Activating Factor; Quinolines; Rabbits; Thiophenes; Thromboxane-A Synthase	1989
Platelet-activating factor (PAF) stimulates phosphatidylinositol hydrolysis in human peripheral blood mononuclear leukocytes. Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:2 Topics: Calcium Channels; Cholera Toxin; Furans; Humans; Hydrolysis; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Platelet Activating Factor; Virulence Factors, Bordetella	1989
(+/-)-trans-2-(3-Methoxy-5-methylsulfonyl-4-propoxyphenyl)-5-(3,4,5- trimethoxyphenyl)tetrahydrofuran (L-659,989), a novel, potent PAF receptor antagonist. Biochemical and biophysical research communications, 1988, Feb-15, Volume: 150, Issue:3 Topics: Acetylglucosaminidase; Animals; Binding, Competitive; Blood Platelets; Cattle; Cell Membrane; Cytoplasmic Granules; Female; Furans; Guinea Pigs; Hematocrit; Humans; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1988
Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2 Topics: Animals; Binding, Competitive; Bronchi; Cell Membrane; Furans; Guinea Pigs; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Tritium	1988
Specific binding of platelet-activating factor (PAF) by human peripheral blood mononuclear leukocytes. Biochemical and biophysical research communications, 1988, Aug-30, Volume: 155, Issue:1 Topics: Alprostadil; Binding, Competitive; Furans; Humans; Kinetics; Leukocytes, Mononuclear; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1988
Platelet-activating factor antagonists increase vascular reactivity in perfused rat lungs. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:5 Topics: Angiotensin II; Animals; Furans; Hypoxia; In Vitro Techniques; Male; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Quinolinium Compounds; Rats; Rats, Inbred Strains; Vasoconstriction	1988
Protective effects of L-659,989, a platelet-activating factor receptor antagonist, in myocardial ischemia and reperfusion in rats. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1 Topics: Animals; Creatine Kinase; Disease Models, Animal; Furans; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Survival Rate	1994
Platelet-activating factor mediates an autocrine proliferative loop in the endometrial adenocarcinoma cell line HEC-1A. Cancer research, 1994, Sep-01, Volume: 54, Issue:17 Topics: Acetyl-CoA C-Acetyltransferase; Adenocarcinoma; Binding, Competitive; Calcium; Cell Count; Cell Cycle; Cell Division; Chromatography, Gas; Endometrial Neoplasms; Female; Furans; Humans; Platelet Activating Factor; Proto-Oncogene Proteins c-fos; RNA; RNA, Messenger; Tumor Cells, Cultured	1994
Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature, 1995, Oct-05, Volume: 377, Issue:6548 Topics: Bacterial Adhesion; Cell Line; Endothelium, Vascular; Furans; Humans; Phosphorylcholine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Streptococcus pneumoniae; Transfection; Virulence	1995
Susceptibility to platelet-activating factor-induced airway hyperreactivity and hyperpermeability: interstrain variation and genetic control. American journal of respiratory cell and molecular biology, 1995, Volume: 13, Issue:5 Topics: Acetylcholine; Airway Resistance; Animals; Capillary Permeability; Female; Furans; Genes; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Circulation; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1995
Tumor necrosis factor induces enhanced responses to platelet-activating factor and differentiation in human monocytic Mono Mac 6 cells. European journal of immunology, 1993, Volume: 23, Issue:4 Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Furans; In Vitro Techniques; Lipopolysaccharide Receptors; Lipopolysaccharides; Monocytes; Phagocytosis; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Superoxides; Tumor Necrosis Factor-alpha	1993
Sequential agonist activation and site-specific mediation of acute cyclosporine constriction in rat renal arterioles. Transplantation, 1994, Dec-27, Volume: 58, Issue:12 Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Fatty Acids, Unsaturated; Furans; Hydrazines; Kidney; Peptides, Cyclic; Platelet Activating Factor; Prostaglandins H; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents	1994
Platelet-activating factor antagonism attenuates platelet and neutrophil activation and reduces myocardial injury during coronary reperfusion. The Journal of surgical research, 1993, Volume: 55, Issue:5 Topics: Adenosine Diphosphate; Animals; Female; Furans; Heart; Hemodynamics; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Myocardial Reperfusion Injury; Neutrophils; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Sheep; Ventricular Function, Left	1993
Platelet-activating factor may stimulate both receptor-dependent and receptor-independent increases in [Ca2+] in human airway epithelial cells. The Journal of biological chemistry, 1994, Feb-11, Volume: 269, Issue:6 Topics: Bronchi; Calcium; Cells, Cultured; Epithelium; Furans; Glyceryl Ethers; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1994
Effect of PAF on human lymphocyte membranes: a fluorescence study. Agents and actions, 1993, Volume: 38 Spec No Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Furans; Half-Life; Humans; Lymphocytes; Platelet Activating Factor	1993
Are leukotrienes or PAF involved in hyperbaric oxygen toxicity? Agents and actions, 1993, Volume: 38, Issue:1-2 Topics: Animals; Benzopyrans; Female; Furans; Indoles; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Oxygen; Platelet Activating Factor; Pressure; Propionates; Quinolines; Rats; Seizures; Specific Pathogen-Free Organisms; SRS-A	1993
Cyclosporine enhances leukocyte adhesion to vascular endothelium under physiologic flow conditions. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 28, Issue:1 Topics: Cell Adhesion; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Furans; Humans; Immunosuppressive Agents; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-1; Leukocytes; Microscopy, Confocal; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Up-Regulation; Vascular Cell Adhesion Molecule-1	1996
Platelet-activating factor antagonism improves ventricular contractility in endotoxemia. Critical care medicine, 1997, Volume: 25, Issue:2 Topics: Animals; Endotoxemia; Endotoxins; Furans; Heart Ventricles; Hemodynamics; Myocardial Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Swine	1997
The role of platelet-activating factor in musculocutaneous flap reperfusion injury. Plastic and reconstructive surgery, 1997, Volume: 99, Issue:7 Topics: Animals; Arteries; Biopsy; Carbon Radioisotopes; Female; Furans; Gene Expression; Graft Survival; Immunohistochemistry; Indium Radioisotopes; Injections, Intra-Arterial; Ischemia; Leukocyte Count; Muscle, Skeletal; Neutrophils; Platelet Activating Factor; Radionuclide Imaging; Radiopharmaceuticals; Reperfusion; Reperfusion Injury; Skin Transplantation; Surgical Flaps; Swine	1997
Platelet activating factor antagonism in pure skin flaps exposed to ischaemia-reperfusion injury. Scandinavian journal of plastic and reconstructive surgery and hand surgery, 1999, Volume: 33, Issue:2 Topics: Animals; Female; Furans; Neutrophil Activation; Peroxidase; Platelet Activating Factor; Reperfusion Injury; Surgical Flaps; Swine	1999