1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with ketotifen in 37 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (ketotifen) | Trials (ketotifen) | Recent Studies (post-2010) (ketotifen) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 1,212 | 275 | 151 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | ketotifen (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.16 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.838 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.009 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.374 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.187 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.112 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.71 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 2.537 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 2.209 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.872 | |
| Histamine H2 receptor | Homo sapiens (human) | 4.129 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 3.727 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.031 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.16 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 2.537 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0011 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.963 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.046 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.141 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (27.03) | 18.7374 |
| 1990's | 25 (67.57) | 18.2507 |
| 2000's | 2 (5.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bahr, T; Grupe, R; Labes, D; Lohde, C | 1 |
| Yano, S | 1 |
| Holgate, ST; Lai, CK; Lau, CK; Ollier, S | 1 |
| Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D | 2 |
| Ishihara, K; Kuriyama, M; Matsumura, Y; Miyamoto, T; Nakamura, T | 2 |
| Jafary, MH; Mahmood, F; Naqvi, A; Saeed, SA | 1 |
| Becker, K; Förster, W; Lueddeckens, G; Rappold, R | 1 |
| Boichot, E; Braquet, P; Capron, M; Dugas, B; Lagente, V; Liu, FT; Mencia-Huerta, JM; Paul-Eugène, N; Petit-Frère, C | 1 |
| Bouhelal, R; Chapman, ID; Morley, J | 1 |
| Saeed, SA | 1 |
| Mayumi, M; Mikawa, H; Mori, KJ; Morita, M; Tsuruta, S | 1 |
| Arnoux, B; Benveniste, J; Devillier, P; Lalau Keraly, C; Landes, A; Marsac, J | 1 |
| Bian, RL; Wang, XD | 1 |
| Fitton, A; Goa, KL; Grant, SM; Sorkin, EM | 1 |
| Bahr, T; Becker, K; Förster, W; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW | 1 |
| Arnoux, B; Benveniste, J; Denjean, A | 1 |
| Nakamura, T; Nishizawa, Y; Sato, T; Yamato, C | 1 |
| Benveniste, J; Bessou, G; Joly, F; Ninio, E | 1 |
| Mazzoni, L; Morley, J; Page, CP; Sanjar, S | 1 |
| Barnes, PJ; Chung, KF; McCusker, M; Minette, P | 1 |
| Arnoux, B; Benveniste, J; Denjean, A; Morley, J; Nolibe, D; Page, CP | 1 |
| Newhouse, MT; Sears, MR | 1 |
| Morley, J; Sanjar, S | 2 |
| Kamei, C; Nakamura, S; Tasaka, K | 2 |
| Iikura, Y; Iwama, T; Mori, H; Nagai, H; Nishida, H; Takatsu, K | 1 |
| Mita, H; Shida, T | 1 |
| Castagliuolo, I; Eliakim, R; Joshi, MA; Karmeli, F; Kelly, CP; LaMont, JT; O'Keane, CJ; Pothoulakis, C; Rachmilewitz, D | 1 |
| Ikemura, T; Ishii, H; Kitamura, S; Ohmori, K; Sasaki, Y | 1 |
| Arnoux, C; Benveniste, J; Dubray, C; Kahhak, L; Roche, A | 1 |
| Inagaki, N; Koda, A; Nagai, H; Ueno, M | 1 |
| Atuma, C; Engstrand, L; Holm, L | 1 |
| Bardhan, KD; Brown, NJ; Jacob, S; Kalia, N; Reed, MW | 1 |
| Kato, M; Kurose, T; Miyaji, S; Oda, T | 1 |
1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ketotifen
| Article | Year |
|---|---|
Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders.
Topics: Asthma; Bronchi; Humans; Hypersensitivity; Ketotifen; Platelet Activating Factor | 1990 |
3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ketotifen
| Article | Year |
|---|---|
Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans.
Topics: Adult; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Middle Aged; Phthalazines; Platelet Activating Factor; Skin | 1991 |
Inhibitory effect of oral ketotifen on ex vivo platelet activating factor-induced platelet aggregation.
Topics: Administration, Oral; Adult; Differential Threshold; Dose-Response Relationship, Drug; Humans; Ketotifen; Male; Osmolar Concentration; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1991 |
Ketotifen inhibits the cutaneous but not the airway responses to platelet-activating factor in man.
Topics: Adult; Aerosols; Blood Cell Count; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Humans; Ketotifen; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Random Allocation; Skin Tests | 1988 |
33 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and ketotifen
| Article | Year |
|---|---|
Influence of platelet activating factor antagonists on the protamine sulphate stimulated release of histamine from peritoneal mast cells of rats in vitro.
Topics: Acetophenones; Animals; Azepines; Diterpenes; Ginkgolides; Histamine Release; Humans; In Vitro Techniques; Ketotifen; Lactones; Male; Mast Cells; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protamines; Rats; Rats, Inbred Strains; Triazoles | 1992 |
[Drug therapy of asthma by antiallergic agents].
Topics: Asthma; Cromolyn Sodium; Histamine Antagonists; Humans; Ketotifen; ortho-Aminobenzoates; Phthalazines; Platelet Activating Factor; SRS-A | 1992 |
Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer.
Topics: Animals; Azepines; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Hydroxyzine; In Vitro Techniques; Ketotifen; Leukotriene B4; Male; Mast Cells; Pepsin A; Peptide Fragments; Platelet Activating Factor; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; SRS-A; Substance P; Triazoles | 1991 |
Platelet-activating factor (PAF) in allergic diseases: inhibitory effects of anti-allergic drugs, ketotifen and three kampo medicines on PAF production.
Topics: Adult; Cromolyn Sodium; Histamine H1 Antagonists; Humans; Hypersensitivity; Ketotifen; Male; Medicine, Chinese Traditional; Neutrophils; ortho-Aminobenzoates; Platelet Activating Factor; Pollen; Reference Values | 1991 |
Influence of aminophylline and ketotifen in comparison to the lipoxygenase inhibitors NDGA and esculetin and the PAF antagonists WEB 2170 [correction of 2107] and BN 52021 on endothelin-1 induced vaso- and bronchoconstriction.
Topics: Aminophylline; Animals; Azepines; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Ketotifen; Lactones; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Platelet Activating Factor; Platelet Aggregation Inhibitors; Theophylline; Thromboxane B2; Triazoles; Umbelliferones; Vasoconstriction; Vasoconstrictor Agents | 1991 |
Pharmacological modulation of the antigen-induced expression of the low-affinity IgE receptor (Fc epsilon RII/CD23) on rat alveolar macrophages.
Topics: Animals; Antigens; Antigens, Differentiation, B-Lymphocyte; Female; Ketotifen; Macrophages, Alveolar; Male; Mast Cells; Platelet Activating Factor; Rats; Rats, Inbred BN; Receptors, Fc; Receptors, IgE | 1991 |
In re: Letter by Kerrebijn in JACI.
Topics: Animals; Bronchi; Guinea Pigs; Ketotifen; Platelet Activating Factor | 1991 |
Antagonism of PAF and arachidonic acid by ketotifen.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; Ketotifen; Platelet Activating Factor | 1991 |
Ketotifen inhibits PAF-induced actin polymerization in a human eosinophilic leukaemia cell line, EoL-1.
Topics: Actins; Cell Line; Chemotaxis; Eosinophils; Flow Cytometry; Humans; Ketotifen; Leukemia, Eosinophilic, Acute; Platelet Activating Factor; Polymers | 1990 |
Inhibition of human and rabbit platelet activation by Ketotifen.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Cromolyn Sodium; Humans; In Vitro Techniques; Ketotifen; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Rabbits | 1990 |
[Effects of ketotifen on rabbit platelet aggregation and platelet activating factor formation from rat neutrophils].
Topics: Animals; Ketotifen; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred Strains | 1990 |
[Platelet-activating factor in Japanese cedar pollinosis].
Topics: Adult; Female; Humans; Ketotifen; Male; Middle Aged; Platelet Activating Factor; Pollen; Rhinitis, Allergic, Seasonal; Trees | 1990 |
Influence of inhibitors of the eicosanoid metabolism, and of eicosanoids- and PAF-acether antagonists on mortality and some biochemical parameters of three shock models.
Topics: Anaphylaxis; Animals; Aspirin; Diterpenes; Fatty Acids, Unsaturated; Female; Ginkgolides; Imidazoles; Ketotifen; Lactones; Masoprocol; Mice; Naphthalenes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Septic | 1989 |
Effect of PAF-acether in non-human primates.
Topics: Airway Resistance; Animals; Asthma; Bronchial Spasm; Constriction, Pathologic; Cromolyn Sodium; Ketotifen; Lung Compliance; Lung Volume Measurements; Nedocromil; Papio; Platelet Activating Factor; Quinolines | 1988 |
Effect of azelastine on the intracellular Ca2+ mobilization in guinea pig peritoneal macrophages.
Topics: Animals; Calcium; Cells, Cultured; Dinoprostone; Guinea Pigs; Histamine H1 Antagonists; Ketotifen; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Phthalazines; Platelet Activating Factor; Prostaglandins E; Pyridazines | 1988 |
Ketotifen inhibits paf-acether biosynthesis and beta-hexosaminidase release in mouse mast cells stimulated with antigen.
Topics: Acetyltransferases; Animals; beta-N-Acetylhexosaminidases; Cell Survival; In Vitro Techniques; Ketotifen; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Platelet Activating Factor | 1987 |
Effects of ketotifen upon responses to platelet activating factor: a basis for asthma prophylaxis.
Topics: Albuterol; Asthma; Cromolyn Sodium; Humans; Hypersensitivity; Injections, Intravenous; Ketotifen; Lung; Mast Cells; Platelet Activating Factor; Platelet Aggregation; Theophylline; Time Factors | 1986 |
Accumulation of platelets and eosinophils in baboon lung after paf-acether challenge. Inhibition by ketotifen.
Topics: Animals; Blood Platelets; Eosinophils; Ketotifen; Lung; Papio; Platelet Activating Factor; Pressure; Respiration | 1988 |
Platelet activating factor, ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1986 |
Ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1986 |
PAF, ketotifen and asthma.
Topics: Asthma; Humans; Ketotifen; Platelet Activating Factor | 1987 |
Effects of antiallergic agents including levocabastine on experimental rhinitis in rats.
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Histamine; Histamine H1 Antagonists; Ketotifen; Male; Nasal Mucosa; Piperidines; Platelet Activating Factor; Rats; Rats, Wistar; Rhinitis; Substance P | 1994 |
Ketotifen and nitroxides decrease capsaicin-augmented ethanol-induced gastric damage in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Cyclic N-Oxides; Ethanol; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Ketotifen; Leukotriene B4; Leukotriene C4; Male; Mast Cells; Nerve Fibers; Platelet Activating Factor; Premedication; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Spin Labels; Stomach Ulcer | 1995 |
Increase in respiratory resistance after exercise in conscious guinea pigs. As a model for exercise-induced asthma.
Topics: Airway Resistance; Animals; Asthma, Exercise-Induced; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; Interleukin-5; Ketotifen; Lipopolysaccharides; Male; Metyrapone; Physical Exertion; Platelet Activating Factor; Prednisolone | 1995 |
Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes.
Topics: Asthma; Calcimycin; Dibenzazepines; Histamine H1 Antagonists; Humans; Hypersensitivity; Imidazoles; Immunoglobulin E; In Vitro Techniques; Ketotifen; Leukocytes; Leukotriene C4; Neutrophils; Piperazines; Platelet Activating Factor | 1995 |
Inhibitory effect of epinastine on bronchoconstriction induced by histamine, platelet activating factor and serotonin in guinea pigs and rats.
Topics: Airway Resistance; Animals; Antigen-Antibody Reactions; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Ketotifen; Male; Phthalazines; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin Antagonists | 1994 |
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum.
Topics: Animals; Bacterial Toxins; Chemotaxis, Leukocyte; Endopeptidases; Enteritis; Enterotoxins; Ileal Diseases; Ileum; Intestinal Mucosa; Ketotifen; Leukotriene B4; Male; Mannitol; Mast Cells; Neutrophils; Permeability; Platelet Activating Factor; Rats; Rats, Wistar; SRS-A | 1993 |
[Effect of KW-4679, a novel antiallergic drug, on platelet-activating factor (PAF)-induced bronchoconstriction, airway hyperresponsiveness and pulmonary cell accumulation in guinea pigs].
Topics: Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dibenzoxepins; Guinea Pigs; Ketotifen; Leukocyte Count; Male; Olopatadine Hydrochloride; Platelet Activating Factor; Rabbits | 1995 |
Decrease of ciliary beat frequency by platelet activating factor: protective effect of ketotifen.
Topics: Animals; Azepines; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; Ketotifen; Mucociliary Clearance; Platelet Activating Factor; Platelet Aggregation Inhibitors; Trachea; Triazoles | 1996 |
Antiallergic action of betotastine besilate (TAU-284) in animal models: A comparison with ketotifen.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Disease Models, Animal; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity; Ketotifen; Male; Passive Cutaneous Anaphylaxis; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 1998 |
Helicobacter pylori extracts reduce gastric mucosal blood flow by a nitric oxide-independent but mast cell- and platelet-activating factor receptor-dependent pathway in rats.
Topics: Animals; Azepines; Blood Pressure; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; In Vitro Techniques; Ketotifen; Laser-Doppler Flowmetry; Male; Mast Cells; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Inbred Lew; Triazoles | 1999 |
Mechanisms of Helicobacter pylori-induced rat gastric mucosal microcirculatory disturbances in vivo.
Topics: Animals; Arginine; Blood Platelets; Dinoprostone; Gastric Mucosa; Helicobacter pylori; Histamine H1 Antagonists; Ketotifen; Leukocytes; Leukotriene B4; Male; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serum Albumin; Thromboxane A2 | 2000 |
The role of platelet activating factor and the efficacy of apafant ophthalmic solution in experimental allergic conjunctivitis.
Topics: Animals; Antigens; Azepines; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Dye Dilution Technique; Guinea Pigs; Humans; Immunization, Passive; Ketotifen; Male; Ophthalmic Solutions; Platelet Activating Factor; Pruritus; Time Factors; Triazoles | 2003 |