1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with interleukin-8 in 153 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (interleukin-8) | Trials (interleukin-8) | Recent Studies (post-2010) (interleukin-8) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 23,523 | 1,167 | 9,990 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.27) | 18.7374 |
| 1990's | 86 (56.21) | 18.2507 |
| 2000's | 49 (32.03) | 29.6817 |
| 2010's | 12 (7.84) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| Hugli, TE; Jagels, MA | 1 |
| Hakkert, BC; Hart, MH; Kuijpers, TW; Roos, D | 1 |
| Catania, A; Hiltz, ME; Lipton, JM | 1 |
| Anderson, DC; Dreyer, WJ; Entman, ML; Michael, LH; Nguyen, T; Rossen, RD; Smith, CW | 1 |
| Baggiolini, M; Bazzoni, F; Berton, G; Cassatella, MA; Ceska, M; Ferro, I | 1 |
| Andersson, PB; Gordon, S; Perry, VH | 1 |
| Bocchietto, E; Bussolino, F; Mantovani, A; Sironi, M | 1 |
| Baggiolini, M; Dahinden, CA; de Weck, AL; Wirthmueller, U | 1 |
| Bruijnzeel, PL; Koenderman, L; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Brunner, T; Dahinden, CA; de Weck, AL | 1 |
| Ahnfelt-Rønne, I; Kirstein, D; Larsen, CG; Skak-Nielsen, T; Thestrup-Pedersen, K; Thomsen, HK; Thomsen, MK | 1 |
| Burrows, LJ; Lindley, ID; Piper, PJ; Westwick, J | 1 |
| Abbass, O; Abbassi, O; Anderson, DC; Butcher, E; Hughes, B; Kishimoto, TK; McIntire, LV; Rothlein, R; Smith, CW | 1 |
| Baggiolini, M; Dahinden, CA; Deranleau, DA; Kernen, P; Spry, CJ; Tai, PC; von Tscharner, V; Wymann, MP | 1 |
| Baggiolini, M; Bohnsack, JF; Carveth, HJ; McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Cunha, FQ; Ferreira, SH; Heluy-Neto, NE; Klein, A; Souza, GE | 1 |
| Kay, AB | 1 |
| Soter, NA; Wintroub, BU | 1 |
| Benveniste, J; Czarnetzki, BM | 1 |
| Davidson, D; Tan, ND | 1 |
| Fisher, A; Nash, GB; Rainger, GE; Shearman, C | 1 |
| Formela, LJ; Galloway, SW; Kingsnorth, AN | 1 |
| Au, BT; Collins, PD; Williams, TJ | 1 |
| Buurman, WA; von Asmuth, EJ | 1 |
| Lorant, DE; McEver, RP; McIntyre, TM; Moore, KL; Prescott, SM; Zimmerman, GA | 1 |
| Chuluyan, HE; Issekutz, AC; Schall, TJ; Yoshimura, T | 1 |
| Hirai, K; Iida, M; Ito, K; Kasahara, T; Miyamasu, M; Morita, Y; Ohta, K; Ohtoshi, T; Takahashi, Y; Takaishi, T | 1 |
| Flower, RJ; Harris, JG; Perretti, M | 1 |
| Koyama, S; Rennard, SI; Robbins, RA | 1 |
| Chuluyan, HE; Issekutz, AC; Lopes, N | 1 |
| Colotta, F; Fadlon, EJ; Mantovani, A; Matteucci, C; Orlando, S; Sozzani, S | 1 |
| Bolanowski, MA; Nourshargh, S; Sanz, MJ; Weg, VB | 1 |
| Bates, PJ; Brutinel, WM; Kreofsky, TJ; Limper, AH; Rohrbach, MS; Specks, U | 1 |
| Agwu, DE; Ellenburg, MD; Locati, M; Mantovani, A; McPhail, LC; Rieppi, M; Rojas, A; Sozzani, S | 1 |
| Arakida, Y; Hirasawa, N; Mue, S; Ohuchi, K; Sugidachi, A; Tanabe, J; Watanabe, M | 1 |
| Bignold, LP; Harkin, DG | 1 |
| Mariscalco, MM | 1 |
| Catania, A; Ceriani, G; Lipton, JM; Macaluso, A | 1 |
| Hack, CE; Imai, Y; Kuipers, B; Levi, M; ten Cate, H; ten Cate, JW; van der Poll, T; van Deventer, SJ | 1 |
| Connelly, PA; Farrell, CA; Richard, S; Shaw, AS; Showell, HJ | 1 |
| Marshall, CJ; Saklatvala, J; Thompson, HL | 1 |
| Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV | 1 |
| Borgeat, P; Braquet, P; Palmantier, R; Sanchez, A; Surette, ME | 1 |
| Borgeat, P; McColl, SR; McDonald, PP; Pouliot, M | 1 |
| Aosaki, N; Minezaki, K; Nakamura, H; Nakazawa, H; Ohsuzu, F; Senoh, M; Tuji, C | 1 |
| Colditz, IG; Mulder, K | 1 |
| Bird, IN; Daniels, RH; Finnen, MJ; Hill, ME | 1 |
| Betts, WH; Murphy, GA; Rokicinski, M; Wozniak, A | 1 |
| Betz, S; Bruijnzeel, PL; Koenderman, L; Kuijper, PH; Rihs, S; Warringa, RA | 1 |
| Bruijnzeel, PL; Koenderman, L; Mengelers, HJ; Raaijmakers, JA; Warringa, RA | 1 |
| Aarden, LA; Hack, CE; Jansen, J; Levi, M; ten Cate, H; ten Cate, JW; van der Poll, T; van Deventer, SJ | 1 |
| Brown, ES; Burns, AR; Entman, ML; Kukielka, GL; Lu, H; Mendoza, LH; Rowen, JL; Simon, SI; Smith, CW | 1 |
| Blaser, K; Nauck, M; Perruchoud, AP; Roth, M; Simon, HU; Tamm, M; Yousefi, S | 1 |
| Ciccarelli, A; Cirillo, R; de Crescenzo, G; de Paulis, A; Marone, G; Patella, V | 1 |
| Koyama, S; Kubo, K; Nomura, H; Sato, E; Sekiguchi, M | 1 |
| de Koster, BM; Elferink, JG | 1 |
| Ali, H; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Hilger, RA; Köller, M; König, W | 1 |
| Botha, AJ; Goode, AW; Moore, EE; Moore, FA; Peterson, VM; Silliman, CC | 1 |
| Knol, EF; Liu, L; Lutter, R; Mul, FP; Roos, D | 1 |
| Williams, FM | 1 |
| Buurman, WA; Dentener, MA; Francot, GJ; Hiemstra, PS; Tool, AT; Vandenabeele, P; Verhoeven, AJ | 1 |
| Fisher, AC; Nash, GB; Rainger, GE | 1 |
| Fonteles, MC; Guerrant, RL; Lima, AA; Steiner, TS; Thielman, NM | 1 |
| Boukedes, SS; Campbell, EJ; Campbell, MA; Owen, CA | 1 |
| Arfors, KE; Jurek, A; Lehr, HA; McIntyre, TM; Prescott, SM; Saetzler, RK; Weyrich, AS; Zimmerman, GA | 1 |
| Bezerra, LR; Guerrant, RL; Lima, AA; Lyerly, DM; Maia, ME; Ribeiro, RA; Rocha, MF | 1 |
| April, MJ; Denault, S; Stanková, J | 1 |
| Manna, SK; Samanta, AK; Samanta, S | 1 |
| Stapleton, F; Thakur, A; Willcox, MD | 1 |
| Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Nakayama, T | 1 |
| Thakur, A; Willcox, MD | 1 |
| Barber, LA; Dy, LC; Fertel, RH; Johnson, CA; Kelley, SW; Murphy, RC; Nguyen, TM; Pei, Y; Travers, JB; Williams, DA | 1 |
| Bihl, M; Eickelberg, O; Perruchoud, AP; Roth, M; Stulz, P; Tamm, M | 1 |
| Fukamachi, H; Gleich, GJ; Ishikawa, M; Kawai, H; Kita, H; Miura, T; Motegi, Y; Ohashi, H | 1 |
| Izumi, T; Koyama, S; Kubo, K; Miura, M; Nagai, S; Nomura, H; Sato, E; Yamashita, T | 2 |
| Izumi, T; Koyama, S; Kubo, K; Masubuchi, T; Nagai, S; Sato, E; Sekiguchi, M; Takamizawa, A | 1 |
| Akard, LP; Cui, Y; English, D; Garcia, JG; Siddiqui, RA | 1 |
| Biancone, L; Bussolati, B; Cambi, V; Camussi, G; David, S; Foà, R; Mariano, F | 1 |
| Biffl, WL; Johnson, JL; Moore, EE; Shames, B; Silliman, CC; Tamura, DY; Zallen, G | 1 |
| Battaglia, E; Brizzi, MF; Camussi, G; Del Sorbo, L; Dentelli, P; Garbarino, G; Montrucchio, G; Pegoraro, L | 1 |
| Denizot, Y; Feiss, P; Nathan, N | 1 |
| McNulty, CA; Symon, FA; Wardlaw, AJ | 1 |
| Kawano, Y; Matsui, N; Miyakawa, I; Narahara, H; Nasu, K; Tanaka, Y | 1 |
| Camussi, G; Cavalli, PL; Donati, D; Guida, G; Mariano, F; Piccoli, G; Tetta, C; Verzetti, G | 1 |
| Denham, W; Norman, J | 1 |
| Cunningham, FM; Lees, P; Marr, KA | 1 |
| Binder, R; Kirschfink, M; Kress, A | 1 |
| Friedman, M; Kafoury, RM; Pryor, WA; Salgo, MG; Squadrito, GL; Zou, X | 1 |
| Arbabi, S; Garcia, I; Jelacic, S; Maier, RV; Rosengart, MR | 1 |
| Dent, G; Djukanović, R; Hidi, R; Holgate, ST; Liu, E; Schudt, C; Timmermans, S | 1 |
| Evanson, OA; McClenahan, DJ; Walcheck, BK; Weiss, DJ | 1 |
| Cromwell, O; Kay, AB; Moqbel, R; Sehmi, R; Wardlaw, AJ | 1 |
| Adams, J; Deitch, EA; Fekete, Z; Garced, M; Hauser, CJ; Livingston, DH | 1 |
| Evanson, O; Fagliari, J; McClenahan, D; Weiss, D | 1 |
| Luu, NT; Nash, GB; Rainger, GE | 1 |
| Countryman, NB; Pei, Y; Spandau, DF; Travers, JB; Yi, Q | 1 |
| Calafat, J; Hiemstra, PS; Hordijk, PL; Janssen, H; Mul, FP; Roos, D; van Wetering, S; Zuurbier, AE | 1 |
| Curtis, LD; Imrie, CW; Johnson, CD; Kingsnorth, AN; Larvin, M; Leeder, PC; McKay, C; McMahon, MJ; Neoptolemos, JP; Skaife, P; Toh, SK; Wilson, P | 1 |
| Adams, JM; Deitch, EA; Fekete, Z; Hauser, CJ; Livingston, DH | 1 |
| Gearing, A; Gendelman, HE; Limoges, J; Persidsky, Y; Rasmussen, J; Zheng, J | 1 |
| Kindzelskii, AL; Petty, HR | 1 |
| Belaiche, J; Denis, MA; Louis, E; Louis, R; Malaise, M | 1 |
| Arima, K; Fujisawa, K; Miyakawa, I; Narahara, H; Nasu, K; Sugano, T | 1 |
| Fietzner, K; Fink, L; Grimminger, F; Hattar, K; Himmel, B; Seeger, W; Sibelius, U | 1 |
| Camussi, G; Guida, G; Mariano, F; Tetta, C; Triolo, G | 1 |
| Hanson, AJ; Quinn, MT; Siemsen, DW; Swain, SD | 1 |
| Drost, EM; MacNee, W | 1 |
| Evanson, OA; McClenahan, DJ; Weiss, DJ | 1 |
| Borgquist, JD; Quinn, MT; Swain, SD | 1 |
| Costa, CH; Cunha, FQ; Ferreira, SH; Oliveira, SH | 1 |
| Evanson, OA; Weiss, DJ | 1 |
| Bongrand, P; Farnarier, C; Grès, S; Kaplanski, G; Marin, V; Montero-Julian, F | 1 |
| Hirayama, K; Kashiwabara, H; Nakamura, S; Nakamura, T; Sakaguchi, T; Sunayama, K; Yokoi, Y | 1 |
| Balestrieri, B; Del Vecchio, L; Granata, F; Marone, G; Petraroli, A; Scalia, G; Triggiani, M | 1 |
| Glynos, K; Papapetropoulos, A; Pizurki, L; Roussos, C; Zhou, Z | 1 |
| Bar-Or, D; Curtis, CG; Rael, LT; Shimonkevitz, RP; Thomas, GW; Winkler, JV; Yukl, RL | 1 |
| Bourgeois, M; De Vriese, AS | 1 |
| de Medina, FS; Gálvez, J; Garrido, M; Merlos, M; Ramis, I; Rodríguez-Cabezas, ME; Zarzuelo, A | 1 |
| Bylund, J; Dahlgren, C; Fu, H; Karlsson, A; Pellmé, S | 1 |
| Geng, JG; Ma, YQ; Plow, EF | 1 |
| Alteraifi, AM; Chodniewicz, D; Zhelev, DV | 1 |
| Choi, IH; Choi, JH; Im, SY; Jung, B; Ko, HM; Lee, HK; Lee, HS; Park, SJ; Seo, KH | 1 |
| Gilli, UO; Loetscher, P; Schneider, MK; Seebach, JD | 1 |
| Blázquez, MA; Cerdá-Nicolás, M; Cortijo, J; Estellés, R; Issekutz, AC; Ivorra, MD; Losada, M; Mateo, T; Milian, L; Morcillo, EJ; Nabah, YN; Sanz, MJ | 1 |
| Hagiwara, K; Kanazawa, M; Kikuchi, I; Kikuchi, S; Kobayashi, T; Nagata, M; Sakamoto, Y | 1 |
| Desaulniers, P; Gilbert, C; Marois, S; Naccache, PH; Paré, G; Popa-Nita, O | 1 |
| Mao, YJ; Wang, L; Wang, WJ | 1 |
| Jin, Y; Qin, G; Wang, J; Yu, L; Zhang, J; Zhang, S | 1 |
| Seltmann, H; Travers, JB; Zhang, Q; Zouboulis, CC | 1 |
| He, JL; Lu, J; Xu, GL; Yu, SQ; Zhang, LL; Zhou, M | 1 |
| Bannon, PG; Cartland, S; Geczy, C; Kritharides, L; Orr, Y; Taylor, JM | 1 |
| Eckert, RE; Jones, SL | 1 |
| Fukuda, J; Furukawa, Y; Kawano, Y; Matsumoto, H; Narahara, H; Yuge, A | 1 |
| Furukawa, M; Ikeda, H; Ogura, M; Tada, N; Yamashita, T | 1 |
| Cunningham, FM; Dunkel, B; Page, CP; Rickards, KJ | 1 |
| Blikslager, AT; Cook, VL; Jones, SL; Neuder, LE | 1 |
| Chang, W; Chen, J; Hoyle, GW; Schlueter, CF | 1 |
| Gamache, DA; Hellberg, PE; Pang, IH; Sharif, NA; Xu, S; Yanni, JM | 1 |
| Alrefai, WA; Bhattacharyya, S; Borthakur, A; Dudeja, PK; Ramaswamy, K; Tobacman, JK | 1 |
| Biancani, P; Falk, GW; Harnett, K; Rieder, F; Yerian, L | 1 |
| Brooks, AC; Cunningham, FM; Rickards, KJ | 1 |
| Fischlein, T; Förch, S; Juchem, G; Knott, M; Kreuzer, E; Laufer, S; Nees, S; Reichart, B; Senftl, A; Weiss, DR | 1 |
| Bonnefoy, A; Dumas, E; Martel, C; Neagoe, PE; Sirois, MG | 1 |
| Anbazhagan, AN; Bhattacharyya, S; Borthakur, A; Dudeja, PK; Kumar, A; Tobacman, JK | 1 |
| Alevizos, M; Kalogeromitros, D; Karagkouni, A; Makris, M; Sismanopoulos, N; Theoharides, TC; Vasiadi, M | 1 |
| Degawa-Yamauchi, M; Kanegasaki, S; Kuribayashi, F; Tsuchiya, T; Yamauchi, A | 1 |
| Antonopoulou, S; Chini, M; Demopoulos, CA; Fragopoulou, E; Gargalianos, P; Lazanas, MC; Mangafas, N; Papakonstantinou, VD; Psarra, K; Stamatakis, GM; Tsogas, N; Tsoupras, AB | 1 |
| Borchers, C; Ocana, JA; Rapp, CM; Sahu, RP; Travers, JB; Weyerbacher, J | 1 |
| Gao, R; Tong, Z; Wang, H; Wang, Y; Yang, H; Zhang, C | 1 |
| Gendron, D; Hamel-Côté, G; Lapointe, F; Rola-Pleszczynski, M; Stankova, J | 1 |
| Abd El-Wahab, HAA; Abdel-Aal, AM; Aboraia, AS; Abou-Ghadir, OF; Aboul-Fadl, T; Chae, MH; Geum, SY; Qayed, WS; Shin, SH; Ye, MK | 1 |
8 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and interleukin-8
| Article | Year |
|---|---|
Mediators of hypersensitivity and inflammatory cells in the pathogenesis of bronchial asthma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Asthma, Exercise-Induced; Bronchitis; Chemotactic Factors; Humans; Hypersensitivity; Immunoglobulin E; Interleukin-8; Mast Cells; Platelet Activating Factor; SRS-A | 1983 |
Biology of the mast cell and its role in cutaneous inflammation.
Topics: Animals; Bone Marrow Cells; Chemotactic Factors; Chemotactic Factors, Eosinophil; Cytoplasmic Granules; Dermatitis; Histamine; Humans; Interleukin-8; Lysophosphatidylcholines; Mast Cells; Mitosis; Muscle Contraction; Muscle, Smooth; Nucleotides, Cyclic; Platelet Activating Factor; Proteoglycans; Rats; SRS-A | 1981 |
Neutrophils and myocardial reperfusion injury.
Topics: Animals; Antibodies; Cell Adhesion Molecules; Complement C5a; Disease Models, Animal; Free Radicals; Humans; Interleukin-8; Leukotriene B4; Myocardial Reperfusion Injury; Myocardial Stunning; Neutrophils; Platelet Activating Factor | 1996 |
Diarrhea, demography and cell signaling: lessons from microbial toxins.
Topics: Bacterial Toxins; Cholera; Cyclic AMP; Diarrhea; Enterocolitis, Pseudomembranous; Escherichia coli Infections; Guanylate Cyclase; Humans; Interleukin-8; Nutrition Disorders; Platelet Activating Factor; Population Growth; Signal Transduction | 1997 |
The potential role of therapeutic cytokine manipulation in acute pancreatitis.
Topics: Acute Disease; Animals; Cytokines; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Pancreatitis; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1999 |
Pharmacologic treatment of acute renal failure in sepsis.
Topics: Acute Kidney Injury; Anticoagulants; Antineoplastic Agents; Antithrombins; Endothelins; Growth Substances; Humans; Interleukin-8; Lipoproteins; Natriuretic Peptides; Nitric Oxide Synthase; Platelet Activating Factor; Protein C; Sepsis; Steroids; Tumor Necrosis Factor-alpha | 2003 |
Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis.
Topics: Animals; Endothelial Cells; Esophageal Motility Disorders; Esophageal Neoplasms; Esophagitis; Esophagogastric Junction; Fibrosis; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Mesoderm; Platelet Activating Factor; Reactive Oxygen Species | 2010 |
Lung fluid biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis.
Topics: Antigens, Human Platelet; Biomarkers; Bronchoalveolar Lavage Fluid; Hepatocyte Growth Factor; Humans; Interleukin-8; Lung; Plasminogen Activator Inhibitor 1; Platelet Activating Factor; Receptor for Advanced Glycation End Products; Respiratory Distress Syndrome | 2019 |
3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and interleukin-8
| Article | Year |
|---|---|
Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amylases; C-Reactive Protein; Double-Blind Method; E-Selectin; Female; Humans; Interleukin-6; Interleukin-8; Lipase; Male; Middle Aged; Pancreatitis; Platelet Activating Factor | 1995 |
Postinjury suppression of human neutrophil cytokine production results from the stabilization of inhibitory kappaB.
Topics: Adult; Cytokines; DNA-Binding Proteins; Humans; I-kappa B Proteins; In Vitro Techniques; Interleukin 1 Receptor Antagonist Protein; Interleukin-8; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Postoperative Complications; Sialoglycoproteins; Tumor Necrosis Factor-alpha; Wounds, Nonpenetrating; Wounds, Penetrating | 1999 |
Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis.
Topics: Acute Disease; Adult; Aged; Biomarkers; Double-Blind Method; E-Selectin; Female; Humans; Imidazoles; Interleukin-8; Length of Stay; Leucine; Logistic Models; Male; Middle Aged; Multiple Organ Failure; Pancreatitis; Placebos; Platelet Activating Factor; Prospective Studies | 2001 |
142 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and interleukin-8
| Article | Year |
|---|---|
Neutrophil chemotactic factors promote leukocytosis. A common mechanism for cellular recruitment from bone marrow.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chemotactic Factors; Complement C5a; Dactinomycin; Interleukin-8; Leukocytosis; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyrazoles; Rabbits; Receptors, Formyl Peptide; Receptors, Immunologic | 1992 |
Neutrophil migration across monolayers of cytokine-prestimulated endothelial cells: a role for platelet-activating factor and IL-8.
Topics: Antigens, Surface; Azepines; Cell Adhesion; Cell Movement; Cells, Cultured; Endothelium, Vascular; Female; Furans; Humans; Interleukin-8; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pregnancy; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stimulation, Chemical; Triazoles; Tumor Necrosis Factor-alpha; Umbilical Veins | 1992 |
Alpha-MSH peptides inhibit acute inflammation induced in mice by rIL-1 beta, rIL-6, rTNF-alpha and endogenous pyrogen but not that caused by LTB4, PAF and rIL-8.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Interleukin-1; Interleukin-6; Interleukin-8; Leukotriene B4; Mice; Peptide Fragments; Platelet Activating Factor; Pyrogens; Rabbits; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury.
Topics: Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Dogs; Immune Sera; Immunochemistry; Interleukin-8; Lymph; Myocardium; Neutrophils; Platelet Activating Factor; Rabbits; Reperfusion Injury; Time Factors | 1992 |
IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucyl-phenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway.
Topics: Cells, Cultured; Complement C5a; Cytochalasin B; Gene Expression; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Platelet Activating Factor; RNA, Messenger; Virulence Factors, Bordetella | 1992 |
Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.
Topics: Animals; Brain; Cell Movement; Chemotactic Factors; Female; Interleukin-1; Interleukin-8; Leukocytes; Male; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 1992 |
Synthesis of platelet-activating factor by polymorphonuclear neutrophils stimulated with interleukin-8.
Topics: Acetyltransferases; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Activation; Humans; Interleukin-8; Neutrophils; Platelet Activating Factor | 1992 |
Receptor-operated activation of polymorphonuclear leukocytes: different effects of NAP-1/IL-8 and fMet-Leu-Phe or C5a.
Topics: Arachidonate 5-Lipoxygenase; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides | 1991 |
Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3.
Topics: Chemotaxis, Leukocyte; Complement C5a; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor | 1991 |
Platelet-activating factor induces mediator release by human basophils primed with IL-3, granulocyte-macrophage colony-stimulating factor, or IL-5.
Topics: Basophils; Complement C3a; Complement C5a; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine Release; Humans; In Vitro Techniques; Interleukin-3; Interleukin-5; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Secretory Rate; SRS-A; Time Factors | 1991 |
Recombinant human interleukin-8 is a potent activator of canine neutrophil aggregation, migration, and leukotriene B4 biosynthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Aggregation; Chemotaxis, Leukocyte; Cycloheximide; Dogs; Humans; Injections, Intradermal; Interleukin-1; Interleukin-8; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Skin | 1991 |
Intraperitoneal injection of human recombinant neutrophil-activating factor/interleukin 8 (hrNAF/IL-8) produces a T cell and eosinophil infiltrate in the guinea pig lung. Effect of PAF antagonist WEB2086.
Topics: Animals; Azepines; Eosinophils; Guinea Pigs; Humans; Injections, Intraperitoneal; Interleukin-8; Kinetics; Lung; Platelet Activating Factor; Pulmonary Alveoli; Recombinant Proteins; Serum Albumin, Bovine; T-Lymphocytes; Triazoles | 1991 |
Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro.
Topics: Adult; Antibodies, Monoclonal; Cell Adhesion; Chemotactic Factors; Cytokines; Endothelium, Vascular; Flow Cytometry; Fluorescent Antibody Technique; Humans; Interleukin-8; Neutrophils; Platelet Activating Factor; Receptors, Lymphocyte Homing | 1991 |
Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.
Topics: Alkaloids; Calcium; Complement C5a; Eosinophils; Exocytosis; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Peroxidases; Pertussis Toxin; Platelet Activating Factor; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins.
Topics: Antigens, Surface; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Endothelium, Vascular; Extracellular Matrix; Humans; Integrins; Interleukin-8; Kinetics; Membrane Glycoproteins; Neutrophils; Peptides; Platelet Activating Factor; Subcellular Fractions | 1989 |
Failure of PAF-acether to induce in vivo neutrophil migration.
Topics: Animals; Carrageenan; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Interleukin-8; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1988 |
Effect of synthetic PAF-acether on human neutrophil function.
Topics: Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Complement System Proteins; Glucuronidase; Guinea Pigs; Humans; In Vitro Techniques; Interleukin-8; Lysophosphatidylcholines; Neutrophils; Platelet Activating Factor | 1981 |
Comparative differences and combined effects of interleukin-8, leukotriene B4, and platelet-activating factor on neutrophil chemotaxis of the newborn.
Topics: Adult; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Drug Synergism; Humans; Infant, Newborn; Interleukin-8; Leukotriene B4; Neutrophils; Platelet Activating Factor; Reference Values | 1995 |
Adhesion of flowing neutrophils to cultured endothelial cells after hypoxia and reoxygenation in vitro.
Topics: Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxia; Interleukin-8; Neutrophils; Oxygen; Platelet Activating Factor; Time Factors | 1995 |
Zymosan-induced IL-8 release from human neutrophils involves activation via the CD11b/CD18 receptor and endogenous platelet-activating factor as an autocrine modulator.
Topics: Antibodies, Monoclonal; Calcimycin; CD18 Antigens; Humans; Integrins; Interleukin 1 Receptor Antagonist Protein; Interleukin-8; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sialoglycoproteins; Tetrazoles; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Endothelial cell associated platelet-activating factor (PAF), a costimulatory intermediate in TNF-alpha-induced H2O2 release by adherent neutrophil leukocytes.
Topics: Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interleukin-8; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Thrombin; Tumor Necrosis Factor-alpha; Umbilical Veins | 1995 |
Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces.
Topics: Animals; Binding Sites; Calcium; CD11 Antigens; CD18 Antigens; Cell Adhesion; CHO Cells; Cricetinae; Cytochalasin D; Humans; Interleukin-8; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins | 1995 |
IL-1 activation of endothelium supports VLA-4 (CD49d/CD29)-mediated monocyte transendothelial migration to C5a, MIP-1 alpha, RANTES, and PAF but inhibits migration to MCP-1: a regulatory role for endothelium-derived MCP-1.
Topics: Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL4; Chemokine CCL5; Chemotaxis, Leukocyte; Complement C5a; Cytokines; E-Selectin; Endothelium, Vascular; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-8; Lymphokines; Macrophage Inflammatory Proteins; Monocytes; Monokines; Neutrophils; Platelet Activating Factor; Protozoan Proteins; Receptors, Very Late Antigen; Vascular Cell Adhesion Molecule-1 | 1995 |
Induction of eosinophil cytokine generation by chemoattractants.
Topics: Actin Cytoskeleton; Chemotactic Factors; Complement C5a; Cytochalasin B; Enzyme Inhibitors; Eosinophils; GTP-Binding Proteins; Humans; In Vitro Techniques; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Signal Transduction; Virulence Factors, Bordetella | 1995 |
Alteration of neutrophil trafficking by a lipocortin 1 N-terminus peptide.
Topics: Amino Acid Sequence; Animals; Annexin A1; Anticoagulants; Antigens, Surface; CD18 Antigens; Cell Adhesion; Humans; Interleukin-8; Kinetics; Macrophage Activation; Macrophage-1 Antigen; Male; Mice; Molecular Sequence Data; Neuraminidase; Neutrophils; Peptides; Platelet Activating Factor; Polysaccharides | 1995 |
Bradykinin stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity.
Topics: Animals; Bradykinin; Bronchi; Cattle; Chemokine CCL2; Chemotactic Factors; Epithelium; Interleukin-8; Leukotriene B4; Osmolar Concentration; Platelet Activating Factor | 1995 |
CD11/CD18-independent transendothelial migration of human polymorphonuclear leukocytes and monocytes: involvement of distinct and unique mechanisms.
Topics: Antibodies, Monoclonal; CD11 Antigens; CD8 Antigens; Cell Migration Inhibition; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Endothelium, Vascular; Humans; Interleukin-1; Interleukin-8; Leukotriene B4; Monocytes; Neutrophils; Platelet Activating Factor | 1995 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody.
Topics: Animals; Antibodies, Monoclonal; Calcium; Chemotaxis, Leukocyte; Dactinomycin; Dihydropyridines; Edema; Eosinophils; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Skin | 1995 |
Comparison of neutrophil chemotactic factor release by human and rabbit alveolar macrophages in response to tannin exposure.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Chemotaxis, Leukocyte; Culture Media, Conditioned; Humans; Hydrolyzable Tannins; Interleukin-8; Lipoxygenase Inhibitors; Macrophages, Alveolar; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1995 |
Activation of phospholipase D by interleukin-8 in human neutrophils.
Topics: Dose-Response Relationship, Drug; Enzyme Activation; Interleukin-8; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pertussis Toxin; Phospholipase D; Platelet Activating Factor; Respiratory Burst; Superoxides; Virulence Factors, Bordetella | 1994 |
Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats.
Topics: Animals; Azepines; Benzoquinones; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Furans; Hypersensitivity; Immunization; Interleukin-8; Isoelectric Focusing; Leukocytes; Lipoxygenase Inhibitors; Phospholipid Ethers; Platelet Activating Factor; Rats; Triazoles | 1994 |
Neutrophil polarisation in plasma differs to that induced by endogenous chemoattractants with regard to frequency of uropod formation and requirement for divalent cations.
Topics: Calcium; Cell Communication; Cell Movement; Chemotactic Factors; Complement C5a; Drug Synergism; Humans; Interleukin-8; Leukotriene B4; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1994 |
Leukocytes and the inflammatory response.
Topics: Adhesiveness; Age Factors; Animals; Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Cell Movement; Disease Models, Animal; Endothelium; Humans; Infant, Newborn; Inflammation; Interleukin-8; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Reperfusion Injury; Respiratory Distress Syndrome | 1993 |
Central neurogenic antiinflammatory action of alpha-MSH: modulation of peripheral inflammation induced by cytokines and other mediators of inflammation.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Edema; Female; Inflammation; Injections, Intraventricular; Interleukin-1; Interleukin-8; Leukotriene B4; Mice; Mice, Inbred BALB C; Platelet Activating Factor | 1994 |
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.
Topics: alpha 1-Antitrypsin; Animals; Cytokines; Disease Models, Animal; Endotoxins; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Interleukin-8; Isoquinolines; Leukocyte Count; Leukocyte Elastase; Neutrophils; Pan troglodytes; Pancreatic Elastase; Platelet Activating Factor; Pyridinium Compounds; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tetrahydroisoquinolines; Toxemia; Tumor Necrosis Factor-alpha | 1994 |
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil.
Topics: Benzoquinones; Cell Line; Chemotactic Factors; Complement C5a; Humans; In Vitro Techniques; Interleukin-8; Lactams, Macrocyclic; Leukotriene B4; Models, Biological; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Quinones; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor.
Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Gel; Chromatography, Ion Exchange; Complement C5a; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-8; Isoenzymes; Leukotriene B4; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Platelet Activating Factor; Point Mutation; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Inflammatory effects of ozone in the upper airways of subjects with asthma.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukotriene B4; Male; Nasal Lavage Fluid; Ozone; Platelet Activating Factor; Respiratory Mechanics; Respiratory System | 1994 |
Priming for the synthesis of 5-lipoxygenase products in human blood ex vivo by human granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha.
Topics: Arachidonate 5-Lipoxygenase; Calcimycin; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Induction by chemokines of lipid mediator synthesis in granulocyte-macrophage colony-stimulating factor-treated human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; beta-Thromboglobulin; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukotriene B4; Neutrophils; Peptides; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
Early release of neutrophil chemotactic factor from isolated rat heart subjected to regional ischaemia followed by reperfusion.
Topics: Animals; Chemotaxis; Disease Models, Animal; Hot Temperature; Interleukin-8; Isoquinolines; Male; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors | 1993 |
Migratory responses of ovine neutrophils to inflammatory mediators in vitro and in vivo.
Topics: Animals; Cell Movement; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Female; Interleukin-8; Leukotriene B4; Microscopy; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sheep; Skin; Spectrometry, Gamma | 1993 |
Differential regulation of early phase and late phase responses in human neutrophils by cAMP.
Topics: Adenylyl Cyclases; Arachidonic Acid; Cell Movement; Cell Size; Chemotaxis; Colforsin; Cyclic AMP; Humans; Interleukin-8; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Superoxides; Time Factors | 1993 |
Interleukin-8 primes human neutrophils for enhanced superoxide anion production.
Topics: Calcium; Dose-Response Relationship, Immunologic; Humans; Interleukin-8; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Superoxides | 1993 |
Eosinophil migration in atopic dermatitis. I: Increased migratory responses to N-formyl-methionyl-leucyl-phenylalanine, neutrophil-activating factor, platelet-activating factor, and platelet factor 4.
Topics: Adolescent; Adult; Cell Movement; Chemotaxis, Leukocyte; Complement C5a; Dermatitis, Atopic; Eosinophils; Female; Humans; Interleukin-5; Interleukin-8; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Factor 4 | 1993 |
Upregulation of formyl-peptide and interleukin-8-induced eosinophil chemotaxis in patients with allergic asthma.
Topics: Adult; Asthma; Bronchial Provocation Tests; Chemotaxis, Leukocyte; Complement C5a; Eosinophils; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Up-Regulation | 1993 |
Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6.
Topics: Animals; Antibodies, Monoclonal; Endotoxins; Escherichia coli; Injections, Intravenous; Interleukin-10; Interleukin-6; Interleukin-8; Isoquinolines; Pan troglodytes; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Tetrahydroisoquinolines; Toxemia | 1996 |
Chemotactic factors stimulate CD18-dependent canine neutrophil adherence and motility on lung fibroblasts.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Movement; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Dogs; Female; Fibroblasts; Interleukin-8; Lung; Male; Neutrophils; Platelet Activating Factor; Recombinant Proteins; RNA, Messenger | 1996 |
Platelet-activating factor exerts mitogenic activity and stimulates expression of interleukin 6 and interleukin 8 in human lung fibroblasts via binding to its functional receptor.
Topics: Cells, Cultured; Fibroblasts; Gene Expression; Genes, fos; Genes, jun; Growth Substances; GTP-Binding Proteins; Humans; Interleukin-6; Interleukin-8; Lung; Phosphotyrosine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1996 |
Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Basophils; Binding, Competitive; Bryostatins; Chemokine CCL2; Chemokine CCL5; Complement C5a; Cyclosporine; Histamine Release; Humans; Interleukin-1; Interleukin-8; Kinetics; Lactones; Leukotriene C4; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Platelet Activating Factor; Protein Binding; Tetradecanoylphorbol Acetate | 1996 |
Bradykinin stimulates alveolar macrophages to release neutrophil, monocyte, and eosinophil chemotactic activity.
Topics: Animals; Asthma; Bradykinin; Bronchoalveolar Lavage Fluid; Cattle; Chemotactic Factors, Eosinophil; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Molecular Weight; Monocyte Chemoattractant Proteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4 | 1996 |
Modulation of human neutrophil chemotaxis by the endothelin-B receptor agonist sarafotoxin S6c.
Topics: Calcium; Chemotaxis, Leukocyte; Cytoplasm; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Humans; Interleukin-8; Leukotriene B4; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Endothelin; Vasoconstrictor Agents; Viper Venoms | 1996 |
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
Topics: Amino Acid Sequence; Calcium; Chemotactic Factors; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502.
Topics: Aluminum; Basophils; Calcimycin; Calcium; Depression, Chemical; Gene Expression Regulation; GTP-Binding Proteins; Humans; Interleukin-8; Ionophores; Leukocytes, Mononuclear; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines | 1996 |
Sequential systemic platelet-activating factor and interleukin 8 primes neutrophils in patients with trauma at risk of multiple organ failure.
Topics: Adolescent; Adult; Aged; Female; Humans; Injury Severity Score; Interleukin-8; Male; Middle Aged; Multiple Organ Failure; Neutrophils; Platelet Activating Factor; Time Factors; Wounds and Injuries | 1996 |
Transmigration of human neutrophils across airway epithelial cell monolayers is preferentially in the physiologic basolateral-to-apical direction.
Topics: CD18 Antigens; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Epithelial Cells; Humans; Interleukin-1; Interleukin-8; Lung; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1996 |
Bactericidal/permeability-increasing protein release in whole blood ex vivo: strong induction by lipopolysaccharide and tumor necrosis factor-alpha.
Topics: Antigens, CD; Antimicrobial Cationic Peptides; Blood Bactericidal Activity; Blood Proteins; Complement C5a; Humans; Interleukin-1; Interleukin-8; Kinetics; Leukocyte Elastase; Lipopolysaccharides; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1997 |
Endothelial-borne platelet-activating factor and interleukin-8 rapidly immobilize rolling neutrophils.
Topics: Cell Adhesion; Cell Movement; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxia; Interleukin-8; Neutrophils; P-Selectin; Platelet Activating Factor | 1997 |
Cytokines regulate membrane-bound leukocyte elastase on neutrophils: a novel mechanism for effector activity.
Topics: Humans; Inflammation; Interleukin-8; Ions; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Surface Properties; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking.
Topics: Animals; Antioxidants; Ascorbic Acid; Azepines; Blood Platelets; Cell Adhesion; Cell Aggregation; Chemokine CCL4; Cricetinae; Humans; Interleukin-8; Macrophage Inflammatory Proteins; Monocytes; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Values; Smoking; Time Factors; Triazoles | 1997 |
Clostridium difficile toxin A induces the release of neutrophil chemotactic factors from rat peritoneal macrophages: role of interleukin-1beta, tumor necrosis factor alpha, and leukotrienes.
Topics: Animals; Bacterial Toxins; Chemotaxis, Leukocyte; Clostridioides difficile; Diterpenes; Enterotoxins; Female; Ginkgolides; Indomethacin; Interleukin-1; Interleukin-8; Lactones; Leukotrienes; Macrophages, Peritoneal; Male; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1997 |
Transcriptional activation of the interleukin-8 gene by platelet-activating factor in human peripheral blood monocytes.
Topics: Blotting, Northern; Cell Culture Techniques; Dose-Response Relationship, Immunologic; Gene Expression Regulation; Humans; Interleukin-8; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Transcription, Genetic | 1997 |
Hamycin inhibits IL-8-induced biologic response by modulating its receptor in human polymorphonuclear neutrophils.
Topics: Adjuvants, Immunologic; Antifungal Agents; Antigens, CD; Autoradiography; Biological Transport; Calcium; Cell Survival; Chemotaxis, Leukocyte; Diphenylhexatriene; Drug Combinations; Erythrocyte Membrane; Fluorescent Dyes; Glucose; Humans; Hydrogen Peroxide; Immunoblotting; Interleukin-8; Iodine Radioisotopes; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Normal Distribution; Oxygen Consumption; Phospholipids; Platelet Activating Factor; Polyenes; Protein Binding; Receptors, Interleukin; Receptors, Interleukin-8A; Superoxides; Viscosity | 1997 |
The proinflammatory cytokines and arachidonic acid metabolites in human overnight tears: homeostatic mechanisms.
Topics: Adult; Antibodies, Blocking; Arachidonic Acids; Blotting, Western; Cell Movement; Chemokine CCL2; Chemotaxis; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Homeostasis; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Leukocyte Count; Leukotriene B4; Neutrophils; Ocular Physiological Phenomena; Platelet Activating Factor; Receptors, Fc; Tears; Time Factors | 1998 |
Proinflammatory cytokine-induced and chemical mediator-induced IL-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase-dependent pathway.
Topics: Bronchi; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Epithelial Cells; Humans; Interleukin-1; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Recombinant Proteins; Signal Transduction; Tumor Necrosis Factor-alpha | 1998 |
Cytokine and lipid inflammatory mediator profile of human tears during contact lens associated inflammatory diseases.
Topics: Acute Disease; Analysis of Variance; Cells, Cultured; Contact Lenses; Corneal Ulcer; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation Mediators; Interleukin-8; Keratitis; Leukotriene B4; Lipids; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Fc; Tears | 1998 |
Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis.
Topics: Arachidonic Acid; Cell Line; Cyclooxygenase 2; Cytokines; Dinoprostone; Epidermis; Humans; Interleukin-6; Interleukin-8; Isoenzymes; KB Cells; Keratinocytes; Membrane Proteins; Models, Biological; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1998 |
Hypoxia-induced interleukin-6 and interleukin-8 production is mediated by platelet-activating factor and platelet-derived growth factor in primary human lung cells.
Topics: Cell Division; Cell Hypoxia; Cells, Cultured; Fibroblasts; Gene Expression; Humans; Interleukin-6; Interleukin-8; Lung; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet-Derived Growth Factor; RNA, Messenger; Transcription, Genetic | 1998 |
Sulochrin inhibits eosinophil activation and chemotaxis.
Topics: Animals; Anti-Allergic Agents; Benzoates; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Humans; Immunoglobulin A; Immunoglobulin G; Interleukin-8; Leukotriene B4; Leukotriene C4; Platelet Activating Factor; Sepharose; Superoxides | 1998 |
Bradykinin stimulates type II alveolar cells to release neutrophil and monocyte chemotactic activity and inflammatory cytokines.
Topics: Antibodies; Bradykinin; Bradykinin Receptor Antagonists; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemotactic Factors; Culture Media, Conditioned; Cycloheximide; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Isoquinolines; Leukotriene B4; Lipoxygenase Inhibitors; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pulmonary Alveoli; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Tetrahydroisoquinolines; Transforming Growth Factor beta | 1998 |
Smoke extract stimulates lung epithelial cells to release neutrophil and monocyte chemotactic activity.
Topics: Antibodies; Cells, Cultured; Chromatography, Gel; Cytokines; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Monocyte Chemoattractant Proteins; Nicotiana; Plants, Toxic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Smoke; Time Factors | 1998 |
Chemotactic migration triggers IL-8 generation in neutrophilic leukocytes.
Topics: Animals; Caseins; Cattle; Cells, Cultured; Chemotaxis, Leukocyte; Complement C5a; Endothelium, Vascular; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Synthesis Inhibitors; RNA, Messenger; Zymosan | 1999 |
Interleukin-12 is synthesized by mesangial cells and stimulates platelet-activating factor synthesis, cytoskeletal reorganization, and cell shape change.
Topics: Angiotensin II; Azepines; Cell Size; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Interleukin-12; Interleukin-8; Lipopolysaccharides; Platelet Activating Factor; Platelet Aggregation Inhibitors; Receptors, Interleukin; Receptors, Interleukin-12; RNA, Messenger; Superoxides; Time Factors; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Thrombopoietin stimulates endothelial cell motility and neoangiogenesis by a platelet-activating factor-dependent mechanism.
Topics: Animals; Azepines; Biocompatible Materials; Biological Transport; Cell Division; Cell Movement; Cell Nucleus; Cells, Cultured; Collagen; DNA-Binding Proteins; Drug Combinations; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression; Humans; Interleukin-8; Kinetics; Laminin; Mice; Milk Proteins; Neoplasm Proteins; Neovascularization, Physiologic; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Proteoglycans; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Signal Transduction; STAT1 Transcription Factor; STAT5 Transcription Factor; Thrombopoietin; Trans-Activators; Triazoles; Tyrosine; Umbilical Veins | 1999 |
Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation?
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cytokines; Dinoprostone; Extracorporeal Circulation; Humans; Inflammation Mediators; Interleukin-10; Interleukin-4; Interleukin-6; Interleukin-8; Leukotriene B4; Leukotriene C4; Lipid Metabolism; Lipids; Multiple Organ Failure; Platelet Activating Factor; Prospective Studies; Thromboxane B2; Tumor Necrosis Factor-alpha | 1999 |
Characterization of the integrin and activation steps mediating human eosinophil and neutrophil adhesion to chronically inflamed airway endothelium.
Topics: CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium; Eosinophils; Epithelium; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Humans; Inflammation; Integrins; Interleukin-3; Interleukin-5; Interleukin-8; Nasal Polyps; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Receptors, CCR3; Receptors, Chemokine; Virulence Factors, Bordetella | 1999 |
Platelet-activating factor stimulates cytokine production by human endometrial stromal cells.
Topics: Adult; Cell Line; Chemokine CCL3; Chemokine CCL4; Cytokines; Endometrial Neoplasms; Endometrium; Female; Humans; Interleukin-6; Interleukin-8; Macrophage Colony-Stimulating Factor; Macrophage Inflammatory Proteins; Phospholipid Ethers; Platelet Activating Factor; Sarcoma; Stromal Cells; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Production of platelet-activating factor in patients with sepsis-associated acute renal failure.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Animals; Female; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Male; Middle Aged; Platelet Activating Factor; Sepsis; Tumor Necrosis Factor-alpha | 1999 |
Agonist-induced adherence of equine neutrophils to fibronectin- and serum-coated plastic is CD18 dependent.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Cells, Cultured; Colorimetry; Complement C5a; Fibronectins; Flow Cytometry; Horses; Interleukin-8; Male; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Modulation of C5a-mediated effector functions of human polymorphonuclear leukocytes by tumor necrosis factor alpha and granulocyte macrophage colony-stimulating factor.
Topics: CD18 Antigens; Cell Adhesion Molecules; Cell Degranulation; Chemotaxis, Leukocyte; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-8; Leukotriene B4; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Radioligand Assay; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Induction of inflammatory mediators in human airway epithelial cells by lipid ozonation products.
Topics: Alkanes; Bronchi; Cells, Cultured; Dinoprostone; Enzyme Activation; Epithelial Cells; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Membrane Lipids; Oxidants, Photochemical; Ozone; Peroxides; Phosphatidylcholines; Phospholipases A; Platelet Activating Factor; Type C Phospholipases | 1999 |
Priming interleukin 8 production: role of platelet-activating factor and p38.
Topics: Adult; Calcium; Enzyme Activation; Humans; Interleukin-8; Lipopolysaccharides; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Signal Transduction | 1999 |
Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis.
Topics: Albuterol; Asthma; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; Interleukin-8; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Activating Factor; Rolipram; T-Lymphocytes; Theophylline | 2000 |
The potential of various lipopolysaccharides to release IL-8 and G-CSF.
Topics: Antibodies; Cell Line; Escherichia coli; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Leukotriene B4; Lipopolysaccharides; Osmolar Concentration; Platelet Activating Factor; Polymyxin B; Pseudomonas aeruginosa; Receptors, Leukotriene B4 | 2000 |
Association among filamentous actin content, CD11b expression, and membrane deformability in stimulated and unstimulated bovine neutrophils.
Topics: Actins; Animals; Blood; Cattle; Cell Membrane; Exotoxins; Inflammation; Interleukin-8; Lipopolysaccharides; Macrophage-1 Antigen; Male; Mannheimia haemolytica; Neutrophils; Platelet Activating Factor; Tumor Necrosis Factor-alpha; Zymosan | 2000 |
Interleukin-8 is a chemo-attractant for eosinophils purified from subjects with a blood eosinophilia but not from normal healthy subjects.
Topics: Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophilia; Eosinophils; Fetal Blood; Humans; Interleukin-3; Interleukin-5; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor | 1993 |
Major trauma enhances store-operated calcium influx in human neutrophils.
Topics: Adult; Calcium; Complement C5a; Female; Humans; In Vitro Techniques; Interleukin-8; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Spectrophotometry; Wounds and Injuries | 2000 |
Role of inflammatory mediators in priming, activation, and deformability of bovine neutrophils.
Topics: Alkaline Phosphatase; Animals; Cattle; Exotoxins; Female; Flow Cytometry; Inflammation Mediators; Interleukin-8; Lactoferrin; Lipopolysaccharides; Luminescent Measurements; Macrophage-1 Antigen; Neutrophils; Peroxidase; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 2000 |
Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils.
Topics: Cell Adhesion; Cell Migration Inhibition; Cells, Cultured; Chemokine CXCL1; Chemokine CXCL5; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Dose-Response Relationship, Immunologic; Endothelium, Vascular; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Chemokine; Receptors, Interleukin; Receptors, Interleukin-8B; Umbilical Veins | 2000 |
Evidence for involvement of the epidermal platelet-activating factor receptor in ultraviolet-B-radiation-induced interleukin-8 production.
Topics: Cells, Cultured; Epidermis; Humans; Interleukin-8; Keratinocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Ultraviolet Rays | 2000 |
Sequential migration of neutrophils across monolayers of endothelial and epithelial cells.
Topics: Adenocarcinoma; Bronchi; CD18 Antigens; Cell Communication; Cell Line, Transformed; Cell Polarity; Cells, Cultured; Chemotaxis, Leukocyte; Coculture Techniques; Complement C5a; Endothelium, Vascular; Epithelial Cells; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Lung; Lung Neoplasms; Microscopy, Electron; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Endothelial Cell Adhesion Molecule-1; Recombinant Proteins; Tumor Cells, Cultured; Umbilical Veins | 2000 |
G-protein receptor responses in trauma neutrophils.
Topics: Adult; Area Under Curve; Calcium; Case-Control Studies; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Female; Growth Substances; Humans; Injury Severity Score; Intercellular Signaling Peptides and Proteins; Interleukin-8; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Cytokine; Receptors, G-Protein-Coupled; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Spectrometry, Fluorescence; Wounds and Injuries | 2000 |
Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
Topics: AIDS Dementia Complex; Animals; Benzyl Compounds; Cell Survival; Dexamethasone; Disease Models, Animal; Drug Combinations; Gliosis; HIV-1; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leucine; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, SCID; Microglia; Neurons; Pentoxifylline; Platelet Activating Factor; Protease Inhibitors; Succinates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
Dissipative metabolic patterns respond during neutrophil transmembrane signaling.
Topics: Antigen-Antibody Complex; Chemotaxis, Leukocyte; Humans; Interferon-gamma; Interleukin-6; Interleukin-8; Leukotriene B4; Ligands; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Platelet Activating Factor; Signal Transduction; Spectrometry, Fluorescence | 2001 |
Increased response of blood eosinophils to various chemotactic agents in quiescent Crohn disease.
Topics: Adult; Chemokine CCL11; Chemokine CCL5; Chemokines, CC; Chemotactic Factors, Eosinophil; Crohn Disease; Cytokines; Eosinophils; Female; Humans; Interleukin-5; Interleukin-8; Male; Middle Aged; Platelet Activating Factor | 2001 |
Effects of platelet-activating factor on cytokine production by human uterine cervical fibroblasts.
Topics: Cells, Cultured; Cervix Uteri; Chemokine CCL2; Chemokine CCL5; Female; Fibroblasts; Gene Expression; Humans; Interleukin-6; Interleukin-8; Phospholipid Ethers; Platelet Activating Factor; RNA, Messenger | 2001 |
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors.
Topics: Arachidonate 5-Lipoxygenase; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Solubility; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Hemofiltration reduces the serum priming activity on neutrophil chemiluminescence in septic patients.
Topics: Acute Kidney Injury; Aged; Blood Physiological Phenomena; Hemofiltration; Humans; Interleukin-8; Luminescent Measurements; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Reference Values; Respiratory Burst; Shock, Septic; Uremia | 2001 |
Activation-induced mobilization of secretory vesicles in bovine neutrophils.
Topics: Alkaline Phosphatase; Animals; Cattle; Inflammation Mediators; Interleukin-8; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Platelet Activating Factor; Secretory Vesicles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Potential role of IL-8, platelet-activating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis.
Topics: Cell Adhesion; Cell Movement; Cell Size; Chemotaxis, Leukocyte; Enzyme Activation; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-8; L-Selectin; Lung; Macrophage-1 Antigen; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tumor Necrosis Factor-alpha | 2002 |
In vitro evaluation of the role of platelet-activating factor and interleukin-8 in Mannheimia haemolytica-induced bovine pulmonary endothelial cell injury.
Topics: Animals; Azepines; Cattle; Cattle Diseases; Cell Adhesion; Cell Degranulation; Coculture Techniques; Endothelium, Vascular; Female; Interleukin-8; Macrophages, Alveolar; Mannheimia haemolytica; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Superoxides; Triazoles | 2002 |
Adhesion to extracellular matrix proteins modulates bovine neutrophil responses to inflammatory mediators.
Topics: Actin Cytoskeleton; Animals; Calcium; Cattle; Cell Adhesion; Cell Degranulation; Cells, Cultured; Extracellular Matrix Proteins; Inflammation Mediators; Interleukin-8; Kinetics; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Reactive Oxygen Species | 2002 |
Sephadex induces eosinophil migration to the rat and mouse peritoneal cavity: involvement of mast cells, LTB4, TNF-alpha, IL-8 and PAF.
Topics: Animals; Cell Movement; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukotriene B4; Male; Mast Cells; Mice; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2002 |
Evaluation of lipopolysaccharide-induced activation of equine neutrophils.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Azepines; CD11 Antigens; CD18 Antigens; Cell Degranulation; Complement System Proteins; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Flow Cytometry; Horses; Interleukin-8; Lipopolysaccharides; Neutrophil Activation; Neutrophils; Pentoxifylline; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles; Tumor Necrosis Factor-alpha | 2002 |
Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: involvement of a metalloproteinase of the TNF-alpha-converting enzyme (TACE) type.
Topics: ADAM Proteins; ADAM17 Protein; Cathepsin G; Cathepsins; Chemotactic Factors; Dipeptides; Humans; Hydroxamic Acids; Interleukin-8; Metalloendopeptidases; Neutrophils; Platelet Activating Factor; Receptors, Interleukin-6; Serine Endopeptidases | 2002 |
Platelet-activating factor, a critical mediator in the pathogenesis of dextran sulfate sodium-induced colitis in rats.
Topics: Analysis of Variance; Animals; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Interleukin-8; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger; Statistics, Nonparametric; Tumor Necrosis Factor-alpha; Up-Regulation | 2003 |
Secretory phospholipases A2 activate selective functions in human eosinophils.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Elapid Venoms; Enzyme Activation; Eosinophils; Glucuronidase; Group II Phospholipases A2; Humans; Hyaluronan Receptors; Interleukin-5; Interleukin-6; Interleukin-8; Lectins, C-Type; Leukotriene C4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phospholipases A; Platelet Activating Factor; Recombinant Proteins; Superoxides; Synovial Membrane | 2003 |
Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production.
Topics: Amides; Angiopoietin-1; Animals; Bradykinin; Capillary Permeability; Cattle; Cell Adhesion; Cell Line; Cells, Cultured; Endothelium, Vascular; Histamine; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lung; Neutrophils; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Thrombin | 2003 |
Copper stimulates the synthesis and release of interleukin-8 in human endothelial cells: a possible early role in systemic inflammatory responses.
Topics: Cells, Cultured; Copper; Culture Media; Cytokines; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Interleukin-1; Interleukin-8; Oligopeptides; Peptides; Platelet Activating Factor; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Umbilical Veins | 2003 |
The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aza Compounds; Azo Compounds; Cell Line; Colitis; Colon; Cytokines; Down-Regulation; Female; Inflammation Mediators; Interleukin-1; Interleukin-8; Mesalamine; Neutrophil Infiltration; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Secondary Prevention; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2003 |
The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8.
Topics: Adult; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cytoskeleton; Enzyme Activation; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Signal Transduction; Tumor Necrosis Factor-alpha | 2004 |
P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of alphaMbeta2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils.
Topics: Antibodies; Cell Adhesion; Fibrinogen; Humans; Interleukin-8; Macrophage-1 Antigen; Membrane Glycoproteins; Neutrophils; P-Selectin; Platelet Activating Factor; Solubility; Up-Regulation | 2004 |
Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.
Topics: Actins; ADP Ribose Transferases; Amides; Anaphylatoxins; Androstadienes; Botulinum Toxins; Chemotactic Factors; Chemotaxis; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pseudopodia; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Wortmannin | 2004 |
Estrogen enhances angiogenesis through a pathway involving platelet-activating factor-mediated nuclear factor-kappaB activation.
Topics: Adenocarcinoma; Animals; Endometrial Neoplasms; Estradiol Congeners; Female; Fibroblast Growth Factor 2; Interleukin-1; Interleukin-8; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; NF-kappa B; Phospholipases A; Phospholipases A2; Platelet Activating Factor; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2004 |
Human polymorphonuclear neutrophils are recruited by porcine chemokines acting on CXC chemokine receptor 2, and platelet-activating factor.
Topics: Animals; Aorta; Cell Line, Transformed; Chemokines; Chemotactic Factors; Chemotaxis, Leukocyte; Endothelial Cells; Humans; Interleukin-8; Neutrophil Infiltration; Platelet Activating Factor; Receptors, Interleukin-8B; Recombinant Proteins; Swine | 2005 |
Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neutrophil recruitment in vivo.
Topics: Angiotensin II; Animals; Aporphines; Chemokine CXCL2; Chemokines; Chemokines, CXC; Endothelial Cells; Humans; Infusions, Parenteral; Intercellular Signaling Peptides and Proteins; Interleukin-8; Keratinocytes; Male; Molecular Structure; Monokines; Neutrophils; P-Selectin; Phenanthrenes; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Eosinophil trans-basement membrane migration induced by interleukin-8 and neutrophils.
Topics: Adult; Antibodies, Monoclonal; Asthma; Azepines; Basement Membrane; Chemotaxis, Leukocyte; Coculture Techniques; Collagen; Culture Media, Conditioned; Drug Combinations; Eosinophils; Humans; Interleukin-8; Laminin; Leukotriene B4; Matrix Metalloproteinase 9; Neutrophil Activation; Neutrophils; Paracrine Communication; Platelet Activating Factor; Protease Inhibitors; Proteoglycans; Pulmonary Eosinophilia; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Characterization of an activation factor released from human neutrophils after stimulation by triclinic monosodium urate crystals.
Topics: Calcium; Chemotaxis, Leukocyte; Crystallization; Humans; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Receptors, Formyl Peptide; Tyrosine; Uric Acid | 2006 |
[Effect of ginkgolide B on the function of rat aorta smooth cells and U937 cells stimulated by oxLDL].
Topics: Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Diterpenes; Dose-Response Relationship, Drug; Ginkgo biloba; Ginkgolides; Humans; I-kappa B Proteins; Interleukin-8; Lactones; Lipoproteins, LDL; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plants, Medicinal; Platelet Activating Factor; Rats; Rats, Wistar; RNA, Messenger; Synaptotagmin I; U937 Cells | 2006 |
Elevated levels of platelet-monocyte aggregates and related circulating biomarkers in patients with acute coronary syndrome.
Topics: Aged; Analysis of Variance; Biomarkers; C-Reactive Protein; CD40 Ligand; Coronary Angiography; Cross-Sectional Studies; Female; Humans; Interleukin-6; Interleukin-8; Logistic Models; Male; Middle Aged; Myocardial Infarction; P-Selectin; Platelet Activating Factor; Probability; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric | 2007 |
Activation of platelet-activating factor receptor in SZ95 sebocytes results in inflammatory cytokine and prostaglandin E2 production.
Topics: Calcium Signaling; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-8; Membrane Proteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Sebaceous Glands | 2006 |
[Protective effect of rupatadine against oleic acid-induced acute lung injury in rabbits].
Topics: Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Cyproheptadine; Enzyme-Linked Immunosorbent Assay; Intercellular Adhesion Molecule-1; Interleukin-8; Lung; Male; Oleic Acid; Platelet Activating Factor; Protective Agents; Rabbits; Random Allocation; Respiratory Distress Syndrome | 2007 |
Conformational activation of CD11b without shedding of L-selectin on circulating human neutrophils.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; CD11b Antigen; Chronic Disease; Complement C3a; Coronary Artery Bypass; Epitopes; Female; Flow Cytometry; Heparin; Humans; Interleukin-8; L-Selectin; Macrophage-1 Antigen; Male; Middle Aged; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Prospective Studies; Protein Conformation; Signal Transduction | 2007 |
Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant.
Topics: Actins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Interleukin-8; Leukotriene B4; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Serine; Signal Transduction; Tumor Necrosis Factor-alpha | 2007 |
The effects of platelet-activating factor on the secretion of interleukin-8 and growth-regulated oncogene alpha in human immortalized granulosa cell line (GC1a).
Topics: Azepines; Cell Line; Chemokine CXCL1; Enzyme-Linked Immunosorbent Assay; Female; Granulosa Cells; Humans; Interleukin-8; Ovulation; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Triazoles | 2007 |
Platelet-activating factor (PAF) induced cytokine production and otitis media with effusion (OME) in the rat middle ear.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; In Vitro Techniques; Interleukin-8; Male; Otitis Media with Effusion; Platelet Activating Factor; Rats; Rats, Wistar | 2008 |
Platelet activation in ponies with airway inflammation.
Topics: Acid Phosphatase; Animals; Antigens; Blood Platelets; Dose-Response Relationship, Drug; Horse Diseases; Horses; Hypersensitivity; Interleukin-8; Lung Diseases, Obstructive; Platelet Activating Factor; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation; Thrombin | 2007 |
The effect of lidocaine on in vitro adhesion and migration of equine neutrophils.
Topics: Anesthetics, Local; Animals; Cell Adhesion; Cell Movement; Horses; Interleukin-8; Leukotriene B4; Lidocaine; Neutrophil Activation; Neutrophils; Platelet Activating Factor | 2009 |
Common pathways for activation of proinflammatory gene expression by G protein-coupled receptors in primary lung epithelial and endothelial cells.
Topics: Animals; Chemokine CXCL1; Endothelial Cells; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Interleukin-8; Lung; Male; Microvessels; Platelet Activating Factor; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Substance P | 2009 |
Human conjunctival epithelial cell responses to platelet-activating factor (PAF): signal transduction and release of proinflammatory cytokines.
Topics: Calcium; Cells, Cultured; Conjunctiva; Cytokines; Data Interpretation, Statistical; Epithelium; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inositol Phosphates; Interleukin-6; Interleukin-8; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction | 2009 |
Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.
Topics: Adaptor Proteins, Signal Transducing; B-Cell CLL-Lymphoma 10 Protein; Blotting, Western; CARD Signaling Adaptor Proteins; Caspases; Cells, Cultured; Colon; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Immunoprecipitation; Interleukin-8; Intestinal Mucosa; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Phosphorylation; Platelet Activating Factor; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2010 |
CXCL8 attenuates chemoattractant-induced equine neutrophil migration.
Topics: Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Chemotactic Factors; Colforsin; Cyclic AMP; Horses; Interleukin-8; Leukotriene B4; Neutrophils; Platelet Activating Factor | 2011 |
Regulation of coronary venular barrier function by blood borne inflammatory mediators and pharmacological tools: insights from novel microvascular wall models.
Topics: Actins; Arterioles; Blood Platelets; Blood Proteins; Capillaries; Capillary Permeability; Cells, Cultured; Coronary Circulation; Dinoprostone; Drug Synergism; Endothelial Cells; Erythrocytes; Hemostatics; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Leukotriene B4; Myocarditis; Pericytes; Platelet Activating Factor; Thrombin; Venules | 2012 |
Angiopoietin-1 but not angiopoietin-2 promotes neutrophil viability: Role of interleukin-8 and platelet-activating factor.
Topics: Angiopoietin-1; Angiopoietin-2; Apoptosis; Cell Survival; Chemotaxis; Humans; Interleukin-8; Neutrophils; Platelet Activating Factor; Receptor, TIE-2 | 2012 |
Lactobacillus acidophilus alleviates platelet-activating factor-induced inflammatory responses in human intestinal epithelial cells.
Topics: Caco-2 Cells; Culture Media, Conditioned; Epithelial Cells; Humans; Interleukin-8; Intestines; Lactobacillus acidophilus; NF-kappa B; Platelet Activating Factor | 2013 |
Rupatadine inhibits inflammatory mediator release from human laboratory of allergic diseases 2 cultured mast cells stimulated by platelet-activating factor.
Topics: Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cyproheptadine; Histamine; Humans; Interleukin-8; Mast Cells; Platelet Activating Factor; Substance P; Tumor Necrosis Factor-alpha | 2013 |
Systematic single cell analysis of migration and morphological changes of human neutrophils over stimulus concentration gradients.
Topics: Adult; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Leukotriene B4; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Primary Cell Culture; Single-Cell Analysis | 2014 |
In vivo effect of two first-line ART regimens on inflammatory mediators in male HIV patients.
Topics: Adenine; Adult; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cyclopropanes; HIV Infections; Humans; Interleukin-10; Interleukin-6; Interleukin-8; Lamivudine; Male; Middle Aged; Organophosphonates; Platelet Activating Factor; Tenofovir; Tumor Necrosis Factor-alpha | 2014 |
Acute Ethanol Exposure Augments Low-Dose UVB-Mediated Systemic Immunosuppression via Enhanced Production of Platelet-Activating Factor Receptor Agonists.
Topics: Animals; Cell Line; Ethanol; Humans; Immune Tolerance; Immunosuppression Therapy; Interleukin-8; Keratinocytes; Mice; Mice, Knockout; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Ultraviolet Rays | 2019 |
Regulation of platelet-activating factor-induced interleukin-8 expression by protein tyrosine phosphatase 1B.
Topics: Binding Sites; CCAAT-Enhancer-Binding Protein-beta; Dendritic Cells; Glycogen Synthase Kinase 3; HEK293 Cells; Humans; Interleukin-8; Models, Biological; Phosphorylation; Phosphothreonine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Promoter Regions, Genetic; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases | 2019 |
Effects of Lidocaine-Derived Organic Compounds on Eosinophil Activation and Survival.
Topics: Anti-Inflammatory Agents; Eosinophils; Interleukin-5; Interleukin-8; Lidocaine; Platelet Activating Factor; Superoxides | 2023 |