1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with indomethacin in 299 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (indomethacin) | Trials (indomethacin) | Recent Studies (post-2010) (indomethacin) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 29,527 | 1,838 | 3,396 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (42.47) | 18.7374 |
| 1990's | 159 (53.18) | 18.2507 |
| 2000's | 12 (4.01) | 29.6817 |
| 2010's | 1 (0.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giessler, C; Mentz, G; Mentz, P; Mest, HJ | 1 |
| Hellewell, PG; Jose, PJ; Williams, TJ | 1 |
| Adler, KB; Akley, NJ; Glasgow, WC | 1 |
| Coëffier, E; Hidi, R; Vargaftig, BB | 1 |
| de Lima, WT; Jancar, S; Sirois, P | 1 |
| Cattaneo, M; Lecchi, A; Mannucci, PM; McGregor, JL; Randi, AM | 1 |
| Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T | 1 |
| Dodam, JR; Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Shankar, G; Stern, PH | 1 |
| Ben-Efraim, S; Bonta, IL; Mozes, T | 1 |
| Cheung, PY; Kucey, DS; Rotstein, OD | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Abraham, WM; Ahmed, T; Mansour, E | 1 |
| Cunningham, FM; Foster, AP; Lees, P | 1 |
| Ackley, NJ; Adler, KB; Crapo, JD; Kinnula, VL | 1 |
| Ferrell, JB; Fleisher, LN; McGahan, MC; Smith, MG | 1 |
| Hu, W; Kinnaird, AA; Man, RY | 1 |
| Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
| Braquet, P; Bueno, L; Droy-Lefaix, MT; Pons, L | 3 |
| Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A | 1 |
| Berti, F; De Angelis, L; Galli, G; Magni, F; Rossoni, G | 1 |
| Arner, M; Högestätt, ED | 1 |
| Chiu, PJ; Foster, CJ; Rivelli, M; Sybertz, EJ; Vemulapalli, S | 1 |
| Braquet, P; Filep, JG; Mózes, T | 1 |
| Braquet, P; Carrier, J; Jancar, S; Sirois, MG; Sirois, P | 1 |
| Gall, DG; MacNaughton, WK | 1 |
| Ben-Efraim, S; Bonta, IL; Heiligers, JP; Mózes, T; Saxena, PR; Tak, CJ; Zijlstra, FJ | 1 |
| Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P | 1 |
| Hu, WM; Man, RY | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Hoshihara, Y; Miyamoto, T; Nogami, M; Shiga, J; Tabuchi, M; Tsubura, K; Yamamoto, T | 1 |
| Bishai, I; Coceani, F; Hynes, N; Lees, J | 1 |
| Boudreau, N; Rabinovitch, M; Turner-Gomes, SO | 1 |
| Bry, K; Hallman, M | 1 |
| Kulikov, VI; Lipatkina, LIu; Orlov, SM; Savel'eva, VF; Vlasov, AA | 1 |
| Hatakeyama, K; Watanabe, K; Yano, S | 1 |
| Kurachi, Y; Nakajima, T; Sugimoto, T | 1 |
| Katayama, T | 1 |
| Kimura, I; Kimura, M; Kobayashi, S; Nakagawa, M | 1 |
| Krell, RD; McCarthy, M | 1 |
| Ban, C; Hasegawa, M; Ihara, Y; Inamori, K; Itoh, H; Li, XM; Mori, T; Okagaki, A; Sagawa, N | 1 |
| Bonne, C; Meynier, F; Muller, A | 1 |
| Iizuka, K; Kawaguchi, H; Takano, H; Yasuda, H | 1 |
| Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Tsurufuji, S; Watanabe, M; Yagi, M | 1 |
| Braquet, P; Carré, C; Lavaud, P; Mencia-Huerta, JM; Rodrigue, F; Touvay, C | 1 |
| Barnes, PJ; Belvisi, MG; Stretton, CD | 1 |
| Bertrand, C; Landry, Y; Tschirhart, E | 1 |
| Evans, RW; Kochanek, PM; Magargee, MJ; Melick, JA; Nemoto, EM; Schoettle, RJ | 2 |
| Myers, AK; Price, RM; Robey, JW | 1 |
| Davidson, D; Singh, M; Wallace, GF | 1 |
| Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
| Andries, R; Bourgain, RH; Braquet, P | 1 |
| Neugarten, J; Schlondorff, D; Yoo, J | 1 |
| Bachelet, M; Dumarey, C; Lefort, J; Malanchere, E; Pretolani, M; Silva, P; Vargaftig, BB | 1 |
| Evans, RD; Ilic, V; Williamson, DH | 1 |
| Andrus, CH; Deshpande, YG; German, D; Kaminski, DL | 1 |
| Csato, M; Dobozy, A; Judák, R; Kenderessy, AS | 1 |
| Ferguson-Chanowitz, KM; Kaplan, JB; Katocs, AS; Kerwar, SS; Oronsky, AL; Pickett, WC; Sass, PM | 1 |
| Durham, SK; Selig, WM; Tocker, JE; Welton, AF | 1 |
| Dunlop, ME; Larkins, RG | 1 |
| Conroy, DM; Piper, PJ; Samhoun, MN | 1 |
| Ikeda, S; Kawasaki, A; Motoishi, M; Nambu, F; Okegawa, T; Omawari, N | 1 |
| de Chaffoy de Courcelles, D; De Clerck, F | 1 |
| McCall, CE; Salzer, WL | 1 |
| Behrens, TW; Goodwin, JS | 1 |
| Buckalew, VM; Handa, RK; Strandhoy, JW | 1 |
| Gimeno, AL; Gimeno, MA; González, E | 1 |
| Kurihara, H; Masaki, T; Morita, T; Oh-hashi, Y; Sugiyama, T; Takaku, F; Yamashita, T; Yanagisawa, M; Yazaki, Y; Yoshizumi, M | 1 |
| Fox, CC; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Schleimer, RP | 1 |
| Gerard, NP | 1 |
| Beijer, L; Botting, J; Crook, P; Oyekan, AO; Page, CP; Rylander, R | 1 |
| Dillon, PK; Durán, WN | 1 |
| Drazen, JM; Galli, SJ; Gerard, NP; Martin, TR | 1 |
| Browning, JL; Cirino, G; Flower, RJ; Peers, SH; Pepinsky, RB | 1 |
| Briand, H; Burka, JF; Pasutto, FM; Scott-Savage, P | 1 |
| Boughton-Smith, NK; Hutcheson, I; Whittle, BJ | 1 |
| Piper, PJ; Yaacob, HB | 1 |
| Ershov, DE; Fedorov, NA; Tatarintsev, AV; Varfolomeev, SD; Vrzheshch, PV; Zaĭtsev, SV | 1 |
| Csató, M; Dobozy, A; Kemény, L | 1 |
| Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P | 1 |
| Ha, B; Jacob, HS; Raij, L; Tolins, JP; Vercellotti, GM; Wilkowske, M | 1 |
| Braquet, P; Jancar, S; Sirois, P | 1 |
| Fitzgerald, MF; Parente, L; Whittle, BJ | 1 |
| Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM | 1 |
| Cirino, G; De Nucci, G; MacNaughton, WK; McKnight, W; Wallace, JL | 1 |
| Calixto, JB; Trebien, HA | 1 |
| Ikeda, K; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Acker, G; Braquet, P; Mencia-Huerta, JM | 1 |
| Dembinska-Kiec, A; Muller, MK; Peskar, BA; Peskar, BM | 1 |
| Bern, MJ; Berschneider, HM; Karayalcin, SS; Powell, DW; Sturbaum, CW; Wachsman, JT | 1 |
| Abraham, WM; Garrido, R; Stevenson, JS | 1 |
| Davenport, NJ; Ezra, D; Feuerstein, GZ; Goldstein, RE; Laurindo, FR | 1 |
| Petty, AC; Scrutton, MC | 1 |
| Calixto, JB; Medeiros, YS; Torres, RC | 1 |
| Dixon, EJ; Page, CP; Robertson, DN; Wilsoncroft, P | 1 |
| Aharony, D; Redkar-Brown, DG | 1 |
| Alila, HW; Battista, PJ; Hansel, W; Rexroad, CE | 1 |
| Espey, LL; Harper, MJ; Okamura, H; Tanaka, N; Woodard, DS | 1 |
| Dale, MM; Penfield, A | 1 |
| Blair, IA; Cragoe, EJ; Frazer, M; Limbird, LE; Reed, PW; Schwartzberg, MS; Sweatt, JD | 1 |
| Antoniw, JW; Piper, PJ; Stanton, AW | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S | 1 |
| Leff, AR; Munoz, NM; Popovich, KJ; Shioya, T; Stimler-Gerard, NP; White, SR | 1 |
| Bradley, LM; Czaja, JF; Feuerstein, G; Goldstein, RE | 1 |
| Ambler, J; Birch, J; Maguire, ED; Wallis, RB | 1 |
| Bush, LR; Smith, SG | 1 |
| Alloatti, G; Benedetto, C; Camussi, G; Emanuelli, G; Massobrio, M; Montrucchio, G; Piva, S; Roffinello, C; Tetta, C; Vigliani, MC | 1 |
| Hattori, Y; Levi, R | 1 |
| Braquet, P; Hébert, RL; Plante, GE; Sirois, P | 1 |
| Piper, PJ; Stewart, AG | 3 |
| Piper, PJ; Stanton, AW; Stewart, AG | 1 |
| Arroyave, JL; Gonzalez-Crussi, F; Hsueh, W | 2 |
| Dierichs, R; Patscheke, H | 1 |
| Altman, R; Scazziota, A | 1 |
| Akkerman, JW; Kloprogge, E | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Mariano, F; Meda, E; Montrucchio, G; Tetta, C | 1 |
| Barnes, PJ; Chung, KF; Evans, TW; Rogers, DF | 1 |
| Altin, JG; Bygrave, FL; Dieter, P | 1 |
| Abbate, M; Bertani, T; Cucchi, M; Delaini, F; Perico, N; Remuzzi, G; Tagliaferri, M | 1 |
| Acker, G; Braquet, P; Etienne, A; Hecquet, F; Mencia-Huerta, JM | 1 |
| Peers, SH | 1 |
| Anderson, GP; Fennessy, MR; White, HL | 1 |
| De Rijke, YB; Kuiper, J; Van Berkel, TJ; Van Waas, MP; Zijlstra, FJ | 1 |
| Kamada, T; Kawano, S; Sato, N; Tsuji, S | 1 |
| Patterson, R; Rubin, AH; Smith, LJ | 1 |
| Dembińska-Kieć, A; Peskar, BA; Peskar, BM | 1 |
| Rosenbaum, JT; Rubin, RM; Samples, JR | 1 |
| Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K | 1 |
| Chu, KM; Gerber, JG; Nies, AS | 1 |
| Aihara, H; Hongoh, K; Kurachi, M; Watanabe, A | 1 |
| Mehta, J; Nichols, WW; Wargovich, T | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Benveniste, J; Brink, C; Brunelleschi, S; Haye-Legrand, I; Labat, C; Norel, X | 1 |
| Braquet, P; Pignol, B; Pouliot, C; Rola-Pleszczynski, M | 1 |
| DeFeudis, FV | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Braquet, P; Jancar, S; Sirois, P; Thériault, P | 1 |
| Brooks, G; Edwards, MC; Evans, FJ; Formukong, E; Williamson, EM | 1 |
| Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB | 1 |
| Czaja, JF; Ezra, D; Feuerstein, G; Goldstein, RE; Laurindo, FR; Snyder, F | 1 |
| Genovese, A; Levi, R; Robertson, DA | 1 |
| Handley, DA; Saunders, RN; Van Valen, RG | 1 |
| Bizios, R; Burhop, KE; Kaplan, JE; Malik, AB; van der Zee, H | 1 |
| Braquet, P; Hebert, RL; Lamoureux, C; Plante, GE; Sirois, P | 1 |
| Honey, AC; Lad, N; Tuffin, DP | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Montrucchio, G; Roffinello, C; Tetta, C | 1 |
| Kogo, H; Matsudaira, T; Satoh, T | 1 |
| Shukla, SD | 1 |
| Baum, T; Pula, K; Rivelli, M; Sybertz, EJ; Watkins, RW | 1 |
| Hwang, SB; Lam, MH; Li, CL; Shen, TY | 1 |
| McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM | 1 |
| Stimler-Gerard, NP | 1 |
| Belin, J; Khan, SN; Sidey, M; Smith, AD; Zilkha, KJ | 1 |
| Korth, R; Mangold, HK; Muramatsu, T; Zöllner, N | 1 |
| Neilsen, NR; Slauson, DO; Wimberly, HC | 1 |
| O'Neill, C | 1 |
| Clark, JS; Jubb, SN; Maloney, PJ; Young, JM | 1 |
| Benveniste, J; Hadji, L; Mencia-Huerta, JM | 1 |
| Haslam, RJ; Vanderwel, M | 1 |
| Ayer, DE; Gorman, RR; Miller, OV | 1 |
| Ford-Hutchinson, AW | 1 |
| Gorman, RR; Hopkins, NK; Lin, AH; Morton, DR | 1 |
| Hillmar, I; Muramatsu, T; Zöllner, N | 1 |
| Gorman, RR; Hopkins, NK; Lin, AH | 1 |
| Lapetina, EG; Siegel, FL | 1 |
| Lee, TC; Malone, B; Snyder, F | 1 |
| Billah, MM; Johnston, JM | 1 |
| Lapetina, EG; Siess, W; Weber, PC | 1 |
| Cheah, MJ; Hwang, SB; Lee, CS; Shen, TY | 1 |
| Bergstrand, H; Dahlbäck, M; Sörenby, L | 1 |
| Corvera, S; García-Sáinz, JA; Mendlovic, F | 1 |
| Barth, T; Bekemeier, H; Hänsel, F; Hirschelmann, R; Sänze, JU | 1 |
| Goldenberg, MM; Meurer, RD | 1 |
| Benveniste, J; Bonnet, J; Page, CP; Paul, W; Pfister, A; Pirotzky, E; Roubin, R | 1 |
| Hamasaki, Y; Mojarad, M; Saga, T; Said, SI; Tai, HH | 1 |
| Beaubien, BB; Morris, HR; Tippins, JR | 1 |
| O'Flaherty, JT; Stimler, NP | 1 |
| Goetzl, EJ; Valone, FH | 1 |
| Hillmar, I; Korth, R; Muramatsu, T; Zöllner, N | 1 |
| Hornby, EJ; Perry, CR | 1 |
| Myers, A; Ramey, E; Ramwell, P | 1 |
| Björk, J; Smedegård, G | 1 |
| Boyd, LM; Ezra, D; Feuerstein, G; Goldstein, RE | 1 |
| Ferreira, SH; Vargaftig, BB | 1 |
| Colwell, JA; Espinoza, GA; Lopes-Virella, MF; Sherwood, T; Shuler, C; Virella, G; Winocour, P | 1 |
| Byers, LW; Chesney, CM; Muirhead, EE; Pifer, DD | 1 |
| Henson, PM; Murphy, RC; Reeves, JT; Voelkel, NF; Worthen, S | 1 |
| Ashley, CJ; Sheppard, H; Tsien, WH | 1 |
| High, JA; Namm, DH | 1 |
| Cox, CP; Farr, RS; Jorgensen, R; Wardlow, ML | 1 |
| Shiga, T; Yoshikawa, D | 1 |
| Jaworek, J; Konturek, SJ | 1 |
| Davison, JS; Mathison, R | 1 |
| Fujii, E; Irie, K; Muraki, T; Ohba, K; Uchida, Y | 1 |
| Conroy, MC; Finkel, M; Grabow, D; Lesch, M; Low, J; Metz, A; Schrier, D; Sommers, C; Wallace, J | 1 |
| Ganbo, T; Hisamatsu, K; Inoue, H; Kikushima, K; Kou, J; Kozuka, Y; Mizukoshi, A; Murakami, Y | 1 |
| Aguilera, JG; Croxatto, HB; Velasquez, LA | 1 |
| Albertini, M; Clement, MG | 2 |
| Chandna, VK; Lawson, DL; Mehta, JL; Yang, BC | 1 |
| Fan, TP; Gresham, GA; Guard, S; Hu, DE; Watling, KJ | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Hirafuji, M; Shinoda, H | 1 |
| Ferrell, J; Fleisher, L; McGahan, C | 1 |
| Bennett, SA; Birnboim, HC | 2 |
| Bueno, L; Delvaux, M; Frexinos, J; Jeanneton, O | 1 |
| Granger, DN; Panés, J; Russell, JM; Wallace, JL; Wolf, RE | 1 |
| Amico-Roxas, M; Caruso, A; Cutuli, VM; De Bernardis, E; Leonardi, G | 1 |
| de Lima, WT; Jancar, S; Kwasniewski, FH; Sirois, P | 1 |
| Chen, SF; Ding, FY; Li, SH | 1 |
| Botella, A; Bueno, L; Delvaux, M; Frexinos, J; Jeanneton, O | 1 |
| Hirayama, K; Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N | 1 |
| Dunn, MJ; Holthöfer, H; Kester, M; Marsden, PA; Nowinski, RJ | 1 |
| Martin, D; Nadler, JV; Peterson, CL; Thompson, MA | 1 |
| Chandel, B; Deshpande, Y; Kaminski, DL; Li, AP; Longo, WE; Stratton, MD; Vernava, AM | 1 |
| Galens, S; Herrnreiter, A; Leff, AR; Mayer, D; McAllister, K; Morton, B; Muñoz, NM; Rabe, KF | 1 |
| Mahmood, F; Rahman, NN; Saeed, SA; Simjee, RU | 1 |
| Boichot, E; Brecx, A; Paubert-Braquet, M; Sidoti, C; Wallace, JL | 1 |
| Fang, GD; Fonteles, MC; Guerrant, RL; Thielman, NM | 1 |
| Hasegawa, S; Hirata, A; Hirata, F; Lee, JY; Nomura, A; Sakamoto, T; Uchida, Y | 1 |
| Dosen, P; Gerkens, JF; Smith, AJ | 1 |
| Dahlén, SE; Jonsson, EW | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Bretschneider, E; Glusa, E; Schrör, K | 1 |
| Deshpande, YG; Feinstein, WK; Kaminski, DL | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 1 |
| Cury, Y; Jancar, S; Oga, S; Teixeira, CF | 1 |
| Chang, SW; Chen, CR; Voelkel, NF | 1 |
| Chayvialle, JA; Cuber, JC; Minaire, Y; Mion, F | 1 |
| Catto-Smith, AG; Gall, DG; Scott, RB; Tan, D | 1 |
| Bugelski, PJ; Esser, KM; Feuerstein, G; Griswold, DE; Hillegass, LM; Rabinovici, R; Vernick, J | 1 |
| Bauer, J; Carlson, RP; Glaser, KB; Hartman, D; Holloway, D; Lock, YW; Sturm, R; Sung, A; Walter, T; Woeppel, S | 1 |
| Northover, AM; Northover, BJ | 1 |
| Endo, C; Hoshi, K; Nakanishi, H; Okawa, T; Sato, A; Suzuki, H; Suzuki, Y | 1 |
| Broussard, JR; Del Vecchio, RP; Dickey, JF; Hansel, W; Thibodeaux, JK | 1 |
| Inoue, K; Kitajima, T; Kubota, Y; Okuhira, M; Tani, K; Yamada, H; Yamaguchi, T | 1 |
| Chen, BN; McLoughlin, JW; Menadue, MF; Norman, RJ; Oliver, JR; Rayner, TE | 1 |
| Anderson, WP; Christy, IJ; Woods, RL | 1 |
| Boichot, E; Braquet, P; Lagente, V; Mencia-Huerta, JM | 1 |
| Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Huang, YC; Kennedy, TP; Piantadosi, CA; Su, YF; Watkins, WD; Whorton, AR | 1 |
| Dodam, JR; Kruse-Elliott, KT; Olson, NC; Whorton, AR | 1 |
| Furukawa, M; Kubo, N; Yamashita, T | 1 |
| Bartula, L; Kadesky, K; Kalley-Taylor, B; Myers, SI; Riva, A; Turnage, R | 1 |
| Mue, S; Ohuchi, K; Watanabe, M; Yamada, M | 3 |
| Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A | 1 |
| Hirafuji, M; Minami, M; Nezu, A; Shinoda, H | 1 |
| Matsumoto, H; Naraba, H; Oh-ishi, S; Ueno, A | 1 |
| Aïssa, J; Arnoux, B; Benveniste, J; Nathan, N | 1 |
| Matsuzaki, T; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Enzan, K; Inaba, H; Kurosawa, S; Yoshioka, N | 1 |
| Juhn, SK; Kim, Y; Less, C; Lin, J; Ondrey, F | 1 |
| Chang, H; Gonzalez-Crussi, F; Hsueh, W; Remick, DG; Tan, X; Wang, H | 1 |
| Andrade, LE; Jancar, S; Rocha, FA; Russo, M | 1 |
| Araújo, CV; Cordeiro, RS; Estato, V; Lopes-Martins, RA; Moreira, S; Tibiriçá, EV | 1 |
| Ishida, H; Oh-Ishi, S; Ueno, A | 1 |
| Hsu, MF; Ko, FN; Lee, TH; Lin, CN; Teng, CM; Wang, JP | 1 |
| Bezerra, LR; Guerrant, RL; Lima, AA; Lyerly, DM; Maia, ME; Ribeiro, RA; Rocha, MF | 1 |
| Balsa, D; Ferrando, R; Forn, J; Garcia-Rafanell, J; Giral, M; Merlos, M | 1 |
| Asano, K; Bitoh, H; Imaki, H; Kurokawa, K; Nakao, A; Nosaka, K; Shimizu, T; Suzuki, T; Taniguchi, S; Watanabe, T | 1 |
| Fukuchi, Y; Ishii, S; Katayama, H; Nagase, T; Ouchi, Y; Shimizu, T | 1 |
| Hu, DH; Ma, CT | 1 |
| Kruse-Elliott, KT | 1 |
| Berón de Astrada, M; Chaud, MA; Franchi, AM; Gimeno, MF | 1 |
| László, F; Whittle, BJ | 1 |
| Shirasawa, E; Tsuji, F | 1 |
| Akbaş, N; Barlas, A; Küçükhüseyin, C; Oncel, H; Payat, M; Silan, C | 1 |
| Bast, A; Buurman, WA; Kramer, K; Pennings, HJ; Wouters, EF | 1 |
| Burstein, SH; Pestonjamasp, VK | 1 |
| Jancar, S; Steil, AA; Tavares de Lima, W | 1 |
| Takami, M; Tsukada, W | 1 |
| Fujii, E; Irie, K; Ishida, H; Muraki, T; Wada, K; Yoshioka, T | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M | 1 |
| Alloatti, G; Camussi, G; De Martino, A; Montrucchio, G; Penna, C | 1 |
| Michibayashi, T | 1 |
| Barbour, SE; Best, AM; Ishihara, Y; Quinn, SM; Schenkein, HA; Tew, JG; Zhang, JB | 1 |
| Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
| Fietzner, K; Fink, L; Grimminger, F; Hattar, K; Himmel, B; Seeger, W; Sibelius, U | 1 |
| Calabrese, R; del Basso, P; Fabi, F; Stati, T | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Tsuyuki, K; Yaginuma, H; Yamada, M | 1 |
| Hanif, S; Khan, FL; Rahman, HB; Rahman, IH; Rasheed, H; Saeed, SA; Shah, BH; Shariff, AH | 1 |
| Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Rasheed, H; Saeed, SA | 1 |
| Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF | 1 |
| Kato, H; Kojima, F; Matsushita, M; Naraba, H; Narumiya, S; Oh-Ishi, S; Sugimoto, Y; Ueno, A; Ushikubi, F; Yuhki, K | 1 |
| Caplan, MS; Jilling, T; Li, D; Lu, J | 1 |
| De Nucci, G; Donato, JL; Lilla, S; Lorenzetti, R; Maziero, AM | 1 |
3 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and indomethacin
| Article | Year |
|---|---|
Mediator release from human basophils and mast cells from lung and intestinal mucosa.
Topics: Antibodies, Anti-Idiotypic; Arachidonic Acid; Arachidonic Acids; Basophils; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Intestinal Mucosa; Leukotriene B4; Lipoxygenase; Lung; Mast Cells; Peptide Hydrolases; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins D; SRS-A | 1985 |
Role of thromboxane A2.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thrombin; Thromboxane A2; Thromboxane B2 | 1985 |
Possible relationship between the syntheses of endothelium-derived relaxing factor (EDRF) and PAF-acether.
Topics: Animals; Endothelium; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Platelet Activating Factor; Vasodilator Agents | 1986 |
296 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and indomethacin
| Article | Year |
|---|---|
Interactions of prostanoids with the platelet activating factors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Guinea Pigs; Heart; Iloprost; In Vitro Techniques; Indomethacin; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxane B2; Triazoles | 1992 |
Inflammatory mechanisms in the passive cutaneous anaphylactic reaction in the rabbit: evidence that novel mediators are involved.
Topics: Animals; Aprotinin; Blood Coagulation Factors; Bradykinin; Complement C5a; Dinoprostone; Edema; Fluoroacetates; Histamine Antagonists; Immunoglobulin E; Indomethacin; Lipoxygenase Inhibitors; Male; Neutrophils; Oligopeptides; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Quinolines; Rabbits; Specific Pathogen-Free Organisms | 1992 |
Platelet-activating factor provokes release of mucin-like glycoproteins from guinea pig respiratory epithelial cells via a lipoxygenase-dependent mechanism.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Epithelium; Glyceryl Ethers; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Mucins; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Trachea | 1992 |
Formation of LTB4 by fMLP-stimulated alveolar macrophages accounts for eosinophil migration in vitro.
Topics: Animals; Benzeneacetamides; Cell Movement; Chemotactic Factors, Eosinophil; Diterpenes; Eosinophils; Ginkgolides; Guinea Pigs; Hydroxamic Acids; Indomethacin; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Sensitivity and Specificity; Stimulation, Chemical | 1992 |
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Bronchoalveolar Lavage Fluid; Dinoprostone; Diterpenes; Econazole; Ginkgolides; Hemoglobins; Hemorrhage; Indomethacin; Lactones; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; Thromboxanes; Triazoles | 1992 |
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Clot Retraction; Collagen; Cyclic AMP; Epinephrine; Fibrinogen; Hemorrhage; Humans; Indomethacin; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Reference Values; Thrombin; Vasoconstrictor Agents; von Willebrand Factor | 1992 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles | 1992 |
Differential effects of WEB 2086 and SRI 63-441 on TNF-alpha-induced alterations in cardiopulmonary function.
Topics: Animals; Azepines; ErbB Receptors; Heart; Indomethacin; Lipids; Lung; Platelet Activating Factor; Platelet Aggregation; Quinolinium Compounds; Swine; Triazoles; Tumor Necrosis Factor-alpha | 1992 |
Interactions of tumor necrosis factor with local and systemic factors in fetal rat limb bones.
Topics: Animals; Azepines; Bone and Bones; Bone Resorption; Culture Techniques; Dexamethasone; Hindlimb; Indomethacin; Interferon-gamma; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Parathyroid Hormone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins; Transforming Growth Factor beta; Triazoles; Tumor Necrosis Factor-alpha | 1992 |
Lethal and non-lethal course of endotoxic shock is determined by interactions between tumor necrosis factor, platelet activating factor and eicosanoids.
Topics: Animals; Blood Pressure; Diterpenes; Eicosanoids; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Lactones; Platelet Activating Factor; Shock, Septic; Swine; Thromboxane B2; Tumor Necrosis Factor-alpha | 1992 |
Platelet-activating factor modulates endotoxin-induced macrophage procoagulant activity by a protein kinase C-dependent mechanism.
Topics: Animals; Blood Coagulation Factors; Calcium; Endotoxins; Female; In Vitro Techniques; Indomethacin; Macrophages; Mice; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Attenuation of platelet-activating factor-induced airway responses with methylprednisolone succinate in sheep.
Topics: Airway Resistance; Animals; Azepines; Bronchoconstriction; Carbachol; Eicosanoids; Indomethacin; Methylprednisolone Hemisuccinate; Platelet Activating Factor; Propionates; Quinolines; Respiratory Mechanics; Sheep; SRS-A; Triazoles | 1992 |
Inflammatory effects of platelet activating factor (PAF) in equine skin.
Topics: Animals; Capillary Permeability; Chlorpheniramine; Dermatitis; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Horse Diseases; Horses; Indomethacin; Injections, Intradermal; Leukocyte Count; Neutrophils; Platelet Activating Factor; Regional Blood Flow; Skin; Skin Temperature | 1992 |
Release of reactive oxygen species by guinea pig tracheal epithelial cells in vitro.
Topics: Analysis of Variance; Animals; Cell Membrane; Cells, Cultured; Epithelium; Guinea Pigs; Hydrogen Peroxide; Indomethacin; Male; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Trachea | 1992 |
Lipid mediators of tumor necrosis factor-alpha-induced uveitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Eicosanoids; Eye Proteins; Indomethacin; Leukocyte Count; Leukotriene B4; Male; Naproxen; Platelet Activating Factor; Prostaglandins E; Quinolinium Compounds; Rabbits; Recombinant Proteins; Tumor Necrosis Factor-alpha; Uveitis, Anterior; Vitreous Body | 1991 |
Mechanisms of the coronary vascular effects of platelet-activating factor in the rat perfused heart.
Topics: Animals; Blood Pressure; Coronary Circulation; Diterpenes; Ginkgolides; Heart; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene Antagonists; Leukotriene B4; Perfusion; Phenylbutyrates; Piperazines; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A | 1991 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
Role of free radicals and platelet-activating factor in the genesis of intestinal motor disturbances induced by Escherichia coli endotoxins in rats.
Topics: Animals; Diarrhea; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diterpenes; Electromyography; Endotoxins; Escherichia coli; Free Radical Scavengers; Free Radicals; Gastrointestinal Motility; Ginkgolides; Indomethacin; Intestine, Small; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1991 |
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma.
Topics: Adult; Aged; Aspirin; Asthma; Basophils; Cytochalasin B; Dexamethasone; Female; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Male; Middle Aged; Platelet Activating Factor | 1990 |
Production and biologic interactions of prostacyclin and platelet-activating factor in acute myocardial ischemia in the perfused rabbit heart.
Topics: Animals; Epoprostenol; In Vitro Techniques; Indomethacin; Male; Myocardial Infarction; Myocardium; Perfusion; Platelet Activating Factor; Polydeoxyribonucleotides; Rabbits | 1990 |
Endothelium-dependent relaxation and effects of prostacyclin, endothelin and platelet-activating factor in human hand veins and arteries.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Arteries; Calcimycin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Epoprostenol; Female; Hand; Humans; Iloprost; Indomethacin; Male; Middle Aged; Platelet Activating Factor; Vasodilation; Veins | 1991 |
Modulation of circulating endothelin levels in hypertension and endotoxemia in rats.
Topics: Animals; Blood Pressure; Chromatography, High Pressure Liquid; Endothelins; Endotoxins; Hypertension; Indomethacin; Lymph; Male; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred SHR; Tumor Necrosis Factor-alpha | 1991 |
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Indomethacin; Lactones; Male; Mesenteric Arteries; Mesenteric Veins; Platelet Activating Factor; Prostaglandins; Reperfusion Injury; Shock; Thromboxane B2 | 1991 |
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; Indomethacin; Lactones; Male; Methysergide; Peritoneal Cavity; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains | 1991 |
Mechanisms of platelet-activating factor-induced electrolyte transport in the rat jejunum.
Topics: Animals; Arachidonic Acids; Azepines; Biological Transport, Active; Chlorides; Dinoprostone; Eicosanoic Acids; Electrophysiology; Female; Indomethacin; Jejunum; Platelet Activating Factor; Quinacrine; Rats; Triazoles | 1991 |
Sequential release of tumour necrosis factor, platelet activating factor and eicosanoids during endotoxin shock in anaesthetized pigs: protective effects of indomethacin.
Topics: Anesthesia; Animals; Blood Chemical Analysis; Blood Glucose; Eicosanoids; Escherichia coli; Female; Hemodynamics; Indomethacin; Lipopolysaccharides; Platelet Activating Factor; Regional Blood Flow; Shock, Septic; Swine; Tumor Necrosis Factor-alpha | 1991 |
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2 | 1991 |
Interaction of vasoactive substances released by platelet-activating factor in the rat perfused heart.
Topics: Animals; Arachidonic Acids; Blood Gas Analysis; Coronary Circulation; Cyclooxygenase Inhibitors; Heart; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Perfusion; Phenylbutyrates; Platelet Activating Factor; Potassium; Rats; Rats, Inbred Strains; Sodium; SRS-A; Vasoconstriction | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
The effect of CV-3988 and CV-6209 on the acute gastric erosions of rats due to water-immersion and restraint stress.
Topics: Analysis of Variance; Animals; Gastric Mucosa; Immersion; Indomethacin; Male; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Physiological | 1991 |
Myoelectric intestinal disturbances in Escherichia coli endotoxic shock in rats. Involvement of platelet-activating factor.
Topics: Animals; Diterpenes; Duodenum; Endotoxins; Escherichia coli; Ginkgolides; Indomethacin; Jejunum; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic | 1991 |
Leukotrienes in cerebrospinal fluid of the conscious cat: effect of platelet-activating factor and pyrogens.
Topics: Animals; Cats; Diterpenes; Endotoxins; Fever; Ginkgolides; Indomethacin; Interleukin-1; Lactones; Leukotrienes; Lipoxygenase Inhibitors; Platelet Activating Factor; Recombinant Proteins; Stimulation, Chemical | 1991 |
Effect of ambient oxygen changes on platelet activating factor production by fetal ovine endothelial cells.
Topics: Acetates; Angiotensin II; Animals; Blood Platelets; Bradykinin; Cells, Cultured; Endothelium, Vascular; Fetus; Hypoxia; Indomethacin; Ionophores; Oxygen; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Sheep | 1991 |
A product of activated human granulocytes stimulates prostaglandin E2 synthesis in human amnion cells.
Topics: Amnion; Cells, Cultured; Chorioamnionitis; Cytochalasin B; Dinoprostone; Epidermal Growth Factor; Female; Free Radical Scavengers; Granulocytes; Hot Temperature; Humans; Indomethacin; Labor, Obstetric; N-Formylmethionine Leucyl-Phenylalanine; Obstetric Labor, Premature; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pregnancy; Protein Synthesis Inhibitors; Stimulation, Chemical | 1991 |
[Effects of phospholipid platelet activation factor on proliferation of B-lymphocytes of the peripheral blood of healthy donors and patients with bronchial asthma].
Topics: Adult; Asthma; B-Lymphocytes; Cell Division; Cells, Cultured; Female; Humans; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lymphocyte Activation; Male; Middle Aged; Platelet Activating Factor; Pokeweed Mitogens | 1991 |
Gastric bleeding and increased gastric vascular permeability induced by platelet activating factor (PAF): effect of drugs that affect arachidonate metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Capillary Permeability; Dinoprostone; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydrocortisone; Imidazoles; Indomethacin; Male; Perfusion; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1991 |
Platelet-activating factor activates cardiac GK via arachidonic acid metabolites.
Topics: Animals; Arachidonic Acids; Benzoquinones; Cells, Cultured; Flavanones; Flavonoids; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Heart Atria; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Membrane Potentials; Myocardium; Platelet Activating Factor; Potassium Channels; Virulence Factors, Bordetella | 1991 |
[The effect of interleukin-1 on ocular inflammation in rabbit ocular tissue].
Topics: Animals; Aqueous Humor; Dinoprostone; Disease Models, Animal; Endophthalmitis; Eye Proteins; Indomethacin; Interleukin-1; Phospholipid Ethers; Platelet Activating Factor; Rabbits | 1991 |
Effects of prostaglandin E2 and cyclooxygenase inhibitors on clustering and level of nicotinic acetylcholine receptor in mouse myotubes co-cultured with spinal cord explant.
Topics: Animals; Aspirin; Cell Communication; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Indomethacin; Kinetics; Masoprocol; Mice; Mice, Inbred Strains; Muscles; Organ Culture Techniques; Platelet Activating Factor; Receptors, Nicotinic; Spinal Cord | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
The involvement of platelet-activating factor in thrombocytopenia and follicular rupture during gonadotropin-induced superovulation in immature rats.
Topics: Animals; Azepines; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Indomethacin; Ovulation; Ovulation Induction; Platelet Activating Factor; Platelet Activation; Platelet Count; Rats; Rats, Inbred Strains; Superovulation; Thrombocytopenia; Triazoles; Vena Cava, Inferior | 1991 |
PAF-induced conjunctivitis in the rabbit is mediated by peptido-leukotrienes.
Topics: Animals; Azepines; Conjunctiva; Conjunctivitis; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Second Messenger Systems; Tetrazoles; Thiazoles; Thienopyridines; Triazoles | 1990 |
Platelet aggregation induced by platelet-activating factor is suppressed by cystine protease inhibitor.
Topics: Animals; Blood Platelets; Calpain; Cathepsin B; In Vitro Techniques; Indomethacin; Piperazines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protease Inhibitors; Rabbits; Serotonin | 1991 |
Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone.
Topics: Animals; Azepines; Cell Adhesion; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Furans; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombin; Triazoles | 1991 |
Pharmacologic modulation of picryl chloride-induced contact dermatitis in the mouse.
Topics: Animals; Betamethasone; Dermatitis, Contact; Dose-Response Relationship, Drug; Indomethacin; Lactones; Male; Methysergide; Mice; Mice, Inbred BALB C; Picryl Chloride; Plant Extracts; Platelet Activating Factor | 1991 |
Bombesin-induced bronchoconstriction in the guinea pig: mode of action.
Topics: Animals; Azepines; Blood Pressure; Bombesin; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Trachea; Triazoles | 1991 |
Selective implication of thromboxane A2 and PAF-acether in two guinea pig anaphylactic models.
Topics: Anaphylaxis; Animals; Antigens; Glyceryl Ethers; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Indomethacin; Muscle Contraction; Platelet Activating Factor; Thiazoles; Thromboxane A2; Trachea | 1990 |
Platelet activating factor antagonists do not alter normal cerebral blood flow or cerebral oxygen consumption.
Topics: Animals; Azepines; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles | 1990 |
Relationships between tumour necrosis factor, eicosanoids and platelet-activating factor as mediators of endotoxin-induced shock in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Capillary Permeability; Diterpenes; Drug Interactions; Eicosanoids; Endotoxins; Escherichia coli; Female; Ginkgolides; Hematocrit; Indomethacin; Lactones; Mice; Platelet Activating Factor; Recombinant Proteins; Shock, Septic; Tumor Necrosis Factor-alpha | 1990 |
Role of leukotriene C4 in pulmonary hypertension: platelet-activating factor vs. hypoxia.
Topics: Animals; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypoxia; Indomethacin; Kinetics; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A | 1990 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
Endotoxin, PAF and arterial thrombosis.
Topics: Animals; Endotoxins; Epoprostenol; Guinea Pigs; Indomethacin; Male; Mesenteric Vascular Occlusion; Platelet Activating Factor; Thrombosis | 1990 |
Thromboxane mediates the renal hemodynamic effects of platelet activating factor.
Topics: Animals; Blood Pressure; Drug Interactions; Glomerular Filtration Rate; Hematocrit; Indomethacin; Kidney; Male; Phenylacetates; Platelet Activating Factor; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Renal Circulation; Sulfonamides; Thromboxane B2 | 1990 |
Protection by nedocromil sodium of active immunization-induced bronchopulmonary alterations in the guinea pig.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchoalveolar Lavage Fluid; Constriction, Pathologic; Eosinophils; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Leukotrienes; Male; Nedocromil; Ovalbumin; Platelet Activating Factor; Quinolones; Respiratory Hypersensitivity; Thromboxane B2 | 1990 |
Metabolic effects of platelet-activating factor in rats in vivo. Stimulation of hepatic glycogenolysis and lipogenesis.
Topics: Animals; Blood Glucose; Female; Furans; Glycogen; Indomethacin; Insulin; Lipids; Liver; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triglycerides | 1990 |
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Absorption; Acute Disease; Animals; Body Water; Cats; Cholecystitis; Gallbladder; Hemodynamics; Indomethacin; Peroxidase; Platelet Activating Factor; Prostaglandins; Prostaglandins E | 1990 |
Inflammatory mediators are involved in the Candida albicans killing activity of human epidermal cells.
Topics: Candida albicans; Dexamethasone; Dinoprostone; Diterpenes; Epidermal Cells; Epidermis; Ginkgolides; Humans; Indomethacin; Inflammation; Interleukin-1; Lactones; Phagocytosis; Platelet Activating Factor; Recombinant Proteins; Ultraviolet Rays | 1990 |
Platelet-activating factor or a platelet-activating factor antagonist decreases tumor necrosis factor-alpha in the plasma of mice treated with endotoxin.
Topics: Alprazolam; Animals; Cell Line; Endotoxins; Enzyme-Linked Immunosorbent Assay; Indomethacin; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Platelet Activating Factor; RNA, Messenger; Shock, Septic; Tumor Necrosis Factor-alpha | 1990 |
Phospholipase A2-induced pulmonary and hemodynamic responses in the guinea pig. Effects of enzyme inhibitors and mediators antagonists.
Topics: Animals; Azepines; Blood Pressure; Bronchi; Bronchoalveolar Lavage Fluid; Dexamethasone; Enzyme Inhibitors; Guinea Pigs; Humans; Indazoles; Indomethacin; Lung; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pressure; Propranolol; Pyrilamine; SRS-A; Trachea; Triazoles | 1990 |
Insulin-dependent contractility of glomerular mesangial cells in response to angiotensin II, platelet-activating factor and endothelin is attenuated by prostaglandin E2.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Cells, Cultured; Dinoprostone; Endothelins; Glomerular Mesangium; Indomethacin; Insulin; Kidney Cortex; Kinetics; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Relaxations of guinea-pig isolated trachea induced by platelet-activating factor are epithelial-dependent and are antagonised by WEB 2086.
Topics: Albuterol; Animals; Azepines; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Platelet Activating Factor; Trachea; Triazoles | 1990 |
Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain.
Topics: Animals; Azepines; Blood Pressure; Brain; Cerebrovascular Circulation; Diterpenes; Ginkgolides; Indomethacin; Lactones; Male; Oxygen; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Triazines; Triazoles | 1990 |
Inhibitory effects of OKY-046 on spasmogen-induced bronchoconstrictions in sensitized and non-sensitized guinea pigs.
Topics: Acrylates; Animals; Blood Pressure; Bordetella pertussis; Bronchi; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Prostaglandin D2; Thromboxane-A Synthase; Trachea | 1990 |
Effect of thromboxane A2 synthetase inhibition, singly and combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on inositol phospholipid turnover and on 5-HT release by washed human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Collagen; Humans; In Vitro Techniques; Indomethacin; Inositol Phosphates; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase | 1990 |
Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Drug Synergism; Endotoxins; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Lipopolysaccharides; Lung; Perfusion; Platelet Activating Factor; Pulmonary Edema; Rabbits; Thromboxanes; Tumor Necrosis Factor-alpha | 1990 |
Control of human T cell proliferation by platelet-activating factor.
Topics: Adult; Animals; CD4 Antigens; Cell Division; Humans; Indomethacin; Leukocytes, Mononuclear; Lymphocyte Activation; Platelet Activating Factor; Sheep; T-Lymphocytes | 1990 |
Platelet-activating factor is a renal vasodilator in the anesthetized rat.
Topics: Anesthesia; Animals; Eicosanoids; Haloperidol; Indomethacin; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Receptors, Dopamine; Renal Circulation; Vasodilator Agents | 1990 |
A novel enhancing effect of platelet activating factor (PAF) on glucose oxidation in uteri from pregnant rats. Participation of prostaglandins and leukotrienes.
Topics: Animals; Carbon Monoxide; Chromones; Female; Glucose; Indomethacin; Leukotrienes; Masoprocol; Platelet Activating Factor; Pregnancy; Pregnancy, Animal; Prostaglandins; Rats; Rats, Inbred Strains; Uterus | 1990 |
Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells.
Topics: Animals; Aorta, Thoracic; Blotting, Northern; Cells, Cultured; Endothelins; Endothelium, Vascular; Gene Expression; Humans; Indomethacin; Interleukin-1; Kinetics; Peptide Biosynthesis; Peptides; Platelet Activating Factor; Pyridinium Compounds; Recombinant Proteins; RNA, Messenger; Swine; Transcription, Genetic | 1990 |
Characterization of substance P contractile activity on isolated guinea pig lung tissues.
Topics: Animals; Dose-Response Relationship, Drug; Glycopeptides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Neurokinin A; Neuropeptides; Platelet Activating Factor; Prostaglandins; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Trachea | 1987 |
The involvement of platelet activating factor in endotoxin-induced pulmonary platelet recruitment in the guinea-pig.
Topics: Animals; Anti-Arrhythmia Agents; Blood Platelets; Endotoxins; Epoprostenol; Female; Guinea Pigs; Heparin; Iloprost; In Vitro Techniques; Indomethacin; Lung; Male; Platelet Activating Factor | 1987 |
Effect of platelet-activating factor on microvascular permselectivity: dose-response relations and pathways of action in the hamster cheek pouch microcirculation.
Topics: Animals; Benzofurans; Blood Pressure; Capillary Permeability; Cheek; Cricetinae; Dexamethasone; Dextrans; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluoresceins; Hematocrit; Indomethacin; Lignans; Macromolecular Substances; Male; Mesocricetus; Methacrylates; Microcirculation; Platelet Activating Factor | 1988 |
Pulmonary responses to bronchoconstrictor agonists in the mouse.
Topics: Animals; Histamine; Indomethacin; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Mice; Mice, Inbred C57BL; Norepinephrine; Platelet Activating Factor; Plethysmography; Propranolol; Prostaglandins; Reference Values; Serotonin; SRS-A; Substance P | 1988 |
Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenalectomy; Animals; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Dexamethasone; Dextrans; Edema; Glycoproteins; Indomethacin; Male; Methotrexate; p-Methoxy-N-methylphenethylamine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyrazoles; Rats; Rats, Inbred Strains; Recombinant Proteins; Serotonin | 1989 |
Leukotriene D4 and platelet-activating factor-acether antagonists on allergic and arachidonic acid-induced reactions in guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Platelet Activating Factor; Respiratory System; SRS-A; Trachea | 1989 |
Relationship between PAF-acether and thromboxane A2 biosynthesis in endotoxin-induced intestinal damage in the rat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Escherichia coli; Ethanol; Imidazoles; Indomethacin; Jejunum; Lipopolysaccharides; Male; Methacrylates; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Interactions of platelet activating factor, thromboxane A2 and leukotrienes in guinea-pig heart.
Topics: Anaphylaxis; Animals; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles | 1989 |
[Kinetics of the cellular response: the phenomenon of supercooperativity in platelet aggregation].
Topics: Adenosine Diphosphate; Alprostadil; Arachidonic Acid; Arachidonic Acids; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1989 |
Pharmacological studies on dithranol-induced irritative dermatitis in mice.
Topics: Animals; Anthralin; Clemastine; Diterpenes; Dose-Response Relationship, Drug; Drug Eruptions; Female; Ginkgolides; Indomethacin; Lactones; Mice; Mice, Inbred Strains; Platelet Activating Factor; Skin; Superoxide Dismutase | 1989 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
Role of platelet activating factor in endotoxemic acute renal failure in the male rat.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Indomethacin; Kidney; Lactones; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Renal Circulation | 1989 |
Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin.
Topics: Animals; Arthus Reaction; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Leukotriene B4; Male; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Release of PAF-acether and eicosanoids from guinea-pig alveolar macrophages by FMLP: effect of cyclo-oxygenase and lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Benzeneacetamides; Cyclooxygenase Inhibitors; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Alveoli; Pyrazoles; Radioimmunoassay; Thromboxane B2 | 1989 |
Involvement of platelet-activating factor (PAF) in endotoxin-induced intestinal motor disturbances in rats.
Topics: Animals; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Diterpenes; Duodenum; Electromyography; Endotoxins; Escherichia coli; Gastrointestinal Motility; Ginkgolides; Indomethacin; Jejunum; Lactones; Male; Muscle, Smooth; Myenteric Plexus; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil | 1989 |
Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach.
Topics: Animals; Blood Pressure; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Ethanol; Ginkgolides; Hydrochloric Acid; Indomethacin; Lactones; Male; Nitroprusside; Peptic Ulcer Hemorrhage; Peptides; Platelet Activating Factor; Propionates; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Stomach; Stomach Ulcer; Vasoconstriction | 1989 |
Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom.
Topics: Animals; Captopril; Crotalid Venoms; Dexamethasone; Edema; Hot Temperature; Indomethacin; Male; Masoprocol; Platelet Activating Factor; Prazosin; Quinacrine; Rats; Rats, Inbred Strains; Reference Values; Yohimbine | 1989 |
Platelet-activating factor increases platelet-dependent glycoconjugate secretion from tracheal submucosal gland.
Topics: Animals; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cats; Fatty Acids, Unsaturated; Glucosamine; Glycoconjugates; Hydrazines; In Vitro Techniques; Indomethacin; Kinetics; Methysergide; Mucous Membrane; Phospholipid Ethers; Platelet Activating Factor; Radioisotope Dilution Technique; Thromboxane A2; Trachea; Tritium | 1989 |
Role of platelet-activating factor (PAF) in the initiation of the decidual reaction in the rat.
Topics: Animals; Decidua; Diterpenes; Female; Ginkgolides; Indomethacin; Lactones; Plant Extracts; Platelet Activating Factor; Pregnancy; Pseudopregnancy; Rats; Rats, Inbred Strains | 1989 |
The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Flow Velocity; Chromatography, High Pressure Liquid; Chromones; Diterpenes; Gastric Mucosa; Ginkgolides; Indomethacin; Lactones; Lipoxygenase Inhibitors; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach; Thromboxane B2 | 1989 |
Immune system control of rat and rabbit colonic electrolyte transport. Role of prostaglandins and enteric nervous system.
Topics: Animals; Biological Transport; Colon; Electric Conductivity; Electrolytes; Free Radicals; Immune System; Immunoglobulin E; Indomethacin; Intestinal Mucosa; Male; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Nervous System; Nervous System Physiological Phenomena; Platelet Activating Factor; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains | 1989 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles | 1989 |
Mechanisms of hypotension produced by platelet-activating factor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Female; Hypotension; Indomethacin; Male; Methacrylates; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Platelet aggregation in whole blood: is the response to adrenaline, 5-hydroxytryptamine and PAF a direct consequence of stimulation by these agonists?
Topics: Apyrase; Azepines; Cell Count; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; Hirudins; Humans; Idazoxan; Indomethacin; Ketanserin; Platelet Activating Factor; Platelet Aggregation; Serotonin; Triazines; Triazoles | 1989 |
Tracheal responsiveness to histamine, PAF-acether and acetylcholine in normal and actively ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; Histamine; Immunization; Indomethacin; Isometric Contraction; Male; Ovalbumin; Platelet Activating Factor; Quinacrine; Trachea | 1989 |
The effect of Paf antagonists on bronchial hyperresponsiveness induced by Paf, propranolol or indomethacin.
Topics: Acetylcholine; Animals; Azepines; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Propranolol; Respiratory Hypersensitivity; Triazines; Triazoles | 1989 |
Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198,615.
Topics: Animals; Antigens; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; Pyrilamine; SRS-A; Trachea | 1989 |
The effects of platelet-activating factor and platelet-derived compounds on bovine luteal cell progesterone production.
Topics: Animals; Blood Platelets; Cattle; Chromatography, High Pressure Liquid; Corpus Luteum; Epidermal Growth Factor; Female; Indomethacin; Luteinizing Hormone; Mianserin; Platelet Activating Factor; Platelet Aggregation; Platelet-Derived Growth Factor; Progesterone; Propranolol; Serotonin | 1989 |
Decrease in ovarian platelet-activating factor during ovulation in the gonadotropin-primed immature rat.
Topics: Androstenols; Animals; Chromatography; Female; Gonadotropins; Indomethacin; Ovary; Ovulation; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1989 |
Comparison of the effects of indomethacin, RHC80267 and R59022 on superoxide production by 1,oleoyl-2,acetyl glycerol and A23187 in human neutrophils.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Cyclohexanes; Cyclohexanones; Diglycerides; Glycerides; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Platelet Activating Factor; Pyrimidinones; Superoxides; Thiazoles | 1987 |
Evidence for a role for Na+-H+ exchange in activation of human platelets by PAF.
Topics: Amiloride; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Humans; Hydrazines; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Protons; Serotonin; Sodium; Thromboxane A2; Thromboxane B2 | 1987 |
Release of leukotrienes from porcine and human blood vessels by immunological and nonimmunological stimuli.
Topics: Animals; Antibodies, Anti-Idiotypic; Blood Vessels; Calcimycin; Cerebral Arteries; Coronary Circulation; Coronary Vessels; Female; Humans; Immunoglobulin E; Immunoglobulin G; Indomethacin; Leukotriene B4; Leukotriene E4; Platelet Activating Factor; Pulmonary Artery; SRS-A; Swine | 1988 |
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin | 1985 |
Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.
Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Platelet Activating Factor; Reference Values; Trachea | 1987 |
Circulatory effects of PAF-acether in newborn piglets.
Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Indomethacin; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Wedge Pressure; Swine; Tetrazoles; Thromboxane B2; Vascular Resistance | 1989 |
Antagonism of U46619-induced aggregation of human and canine platelets by four TXA2 receptor antagonists.
Topics: Adenosine Diphosphate; Animals; Dogs; Epinephrine; Humans; In Vitro Techniques; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1986 |
In vitro oxytocic activity of platelet-activating factor on human myometrium.
Topics: Female; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase; Masoprocol; Myometrium; Oxytocics; Platelet Activating Factor; Pregnancy; Prostaglandin-Endoperoxide Synthases; Uterine Contraction | 1987 |
Effect of PGD2 on cardiac contractility: a negative inotropism secondary to coronary vasoconstriction conceals a primary positive inotropic action.
Topics: Animals; Coronary Circulation; Coronary Vessels; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methacrylates; Myocardial Contraction; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; SRS-A; Stimulation, Chemical; Vasoconstriction | 1986 |
Hemodynamic effects of PAF-acether on the dog kidney.
Topics: Animals; Blood Pressure; Diterpenes; Diuresis; Dogs; Female; Ginkgolides; Glomerular Filtration Rate; Indomethacin; Kidney; Lactones; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Renal Circulation; Sodium | 1987 |
Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Vessels; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lactones; Leukotriene B4; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thromboxane A2; Time Factors; Vasoconstriction | 1987 |
Mechanisms of vascular actions of PAF.
Topics: Animals; Cerebrovascular Circulation; Coronary Circulation; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indomethacin; Leukotriene B4; Platelet Activating Factor; Rats; SRS-A; Swine | 1987 |
Platelet-activating factor-induced ischemic bowel necrosis. An investigation of secondary mediators in its pathogenesis.
Topics: Alprostadil; Animals; Blood Pressure; Catechols; Chromones; Diethylcarbamazine; Disease Models, Animal; Hematocrit; Indomethacin; Intestines; Ischemia; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Masoprocol; Methacrylates; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella typhi; Thromboxane-A Synthase; Verapamil | 1986 |
Cationized ferritin as a platelet-stimulating surface probe. Binding to platelets and effects on platelet function.
Topics: Agglutination; Alprostadil; Binding Sites; Blood Platelets; Dose-Response Relationship, Drug; Edetic Acid; Ferritins; Humans; Indomethacin; Neuraminidase; Plasma; Platelet Activating Factor; Platelet Aggregation; Serotonin; Tritium | 1986 |
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones | 1986 |
Platelet-activating factor-induced vasoconstriction in rat isolated, perfused hearts: contribution of cyclo-oxygenase and lipoxygenase arachidonic acid metabolites.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Circulation; Diethylcarbamazine; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Myocardium; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Vasoconstriction | 1986 |
Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Fibrinogen; Humans; Indomethacin; Kinetics; Macromolecular Substances; Platelet Activating Factor; Prostaglandin Endoperoxides; Protein Binding; Thromboxanes | 1986 |
The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition.
Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Cyclooxygenase Inhibitors; Drug Interactions; Electrocardiography; Female; Hemodynamics; Histamine; Histamine Antagonists; Indomethacin; Infusions, Intravenous; Male; Platelet Activating Factor; Promethazine; Rabbits | 1987 |
Effect of platelet-activating factor on airway vascular permeability: possible mechanisms.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Biomechanical Phenomena; Capillary Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lactones; Male; Plant Extracts; Platelet Activating Factor; Platelet Count; Pyrazoles; Respiratory System; Time Factors | 1987 |
Evidence that Ca2+ fluxes and respiratory, glycogenolytic and vasoconstrictive effects induced by the action of platelet-activating factor and L-alpha-lysophosphatidylcholine in the perfused rat liver are mediated by products of the cyclo-oxygenase pathwa
Topics: Acetophenones; Animals; Calcium; Dose-Response Relationship, Drug; Indomethacin; Liver; Liver Glycogen; Lysophosphatidylcholines; Male; Oxygen Consumption; Perfusion; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1987 |
Effect of platelet-activating factor and its specific receptor antagonist on glomerular permeability to proteins in isolated perfused rat kidney.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antioxidants; Basement Membrane; Cell Membrane Permeability; Cyclooxygenase Inhibitors; Furans; Glomerular Filtration Rate; Indomethacin; Kidney Glomerulus; Lipoxygenase Inhibitors; Male; Microscopy, Electron; Perfusion; Phenothiazines; Platelet Activating Factor; Proteins; Proteinuria; Pyrazoles; Rats; Rats, Inbred Strains; Vascular Resistance | 1988 |
Role of platelet-activating factor (PAF) in the ovoimplantation in the rat: effect of the specific PAF-acether antagonist, BN 52021.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechols; Diterpenes; Dose-Response Relationship, Drug; Embryo Implantation; Female; Ginkgolides; Indomethacin; Kinetics; Lactones; Lipoxygenase Inhibitors; Masoprocol; Platelet Activating Factor; Pyrazoles; Rats; Rats, Inbred Strains; Sulfides | 1988 |
Dexamethasone inhibits platelet activating factor-induced inflammation in the paw but not the pleural cavity of rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Dexamethasone; Edema; Female; Foot; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pleura; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Increased airways responsiveness to histamine induced by platelet activating factor in the guinea-pig: possible role of lipoxygenase metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Atropine Derivatives; Bronchi; Female; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase; Male; Masoprocol; Platelet Activating Factor; Pyrazoles; Vagotomy | 1988 |
The induction of glycogenolysis in the perfused liver by platelet activating factor is mediated by prostaglandin D2 from Kupffer cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Glucose; Glycogen; Indomethacin; Kupffer Cells; Liver; Male; Perfusion; Platelet Activating Factor; Prostaglandin D2; Rats; Rats, Inbred Strains | 1988 |
Microvascular basis of gastric mucosal protection.
Topics: Animals; Calcium; Ethanol; Gastric Mucosa; Indomethacin; Lipid Peroxides; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A | 1988 |
Mechanism of platelet activating factor-induced bronchoconstriction in humans.
Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Dose-Response Relationship, Drug; Humans; Indomethacin; Platelet Activating Factor; Respiratory Function Tests | 1988 |
Release of cysteinyl-leukotrienes is of minor importance in PAF induced reduction of perfusion rate in the gastric vascular bed.
Topics: Animals; Chromones; Cysteine; Diterpenes; Ginkgolides; Indomethacin; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; SRS-A; Stomach | 1988 |
Prostaglandin-independent inhibition of ocular vascular permeability by a platelet-activating factor antagonist.
Topics: Animals; Anterior Chamber; Aqueous Humor; Capillary Permeability; Dexamethasone; Dinoprostone; Drug Synergism; Endophthalmitis; Endotoxins; Eye; Female; Indomethacin; Platelet Activating Factor; Prostaglandins E; Punctures; Quinolinium Compounds; Rabbits | 1988 |
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis | 1988 |
Local vasodilator effect of platelet activating factor in the gastric, mesenteric and femoral arteries of the dog.
Topics: Animals; Dogs; Femoral Artery; Indomethacin; Isomerism; Male; Mesenteric Arteries; Platelet Activating Factor; Stomach; Vasodilation | 1988 |
Suppression of bronchial response to platelet activating factor following taurine administration.
Topics: Animals; Bronchial Spasm; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A; Taurine | 1987 |
Biphasic effects of platelet-activating factor on coronary blood flow in anesthetized dog.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Indomethacin; Male; Platelet Activating Factor; Prostaglandins | 1986 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chromones; Dinoprostone; Indomethacin; Intestine, Small; Methacrylates; Perfusion; Platelet Activating Factor; Prostaglandins E; Rats; SRS-A; Thromboxane B2; Vasoconstriction | 1986 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Serotonin; SRS-A; Thromboxane B2; Trachea | 1987 |
Inhibition of human lymphocyte proliferation and interleukin 2 production by platelet activating factor (PAF-acether): reversal by a specific antagonist, BN 52021.
Topics: Adult; Cells, Cultured; Dinoprostone; Diterpenes; Ginkgolides; Humans; Indomethacin; Interleukin-2; Lactones; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Thromboxane B2 | 1987 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Comparative effects of platelet activating factor, leukotriene D4 and histamine on guinea pig trachea, bronchus and lung parenchyma.
Topics: Airway Resistance; Animals; Bronchi; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lung; Platelet Activating Factor; Pulmonary Circulation; SRS-A; Trachea | 1987 |
Secretion and properties of a polypeptide factor generated by phorbol ester stimulation of human blood platelets.
Topics: Adult; Blood Platelets; Blood Proteins; Humans; Indomethacin; Male; Phorbol Esters; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Stimulation, Chemical; Trypsin | 1987 |
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombocytopenia | 1987 |
Actions of platelet-activating factor in the coronary circulation of the guinea pig in vitro.
Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Platelet Activating Factor; SRS-A | 1987 |
Cardiac and coronary consequences of intracoronary platelet activating factor infusion in the domestic pig.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Coronary Circulation; Coronary Vessels; Female; Heart; Indomethacin; Infusions, Intra-Arterial; Male; Nitroprusside; Platelet Activating Factor; SRS-A; Swine; Thromboxane A2 | 1987 |
Negative inotropic effect of platelet-activating factor on human myocardium: a pharmacological study.
Topics: Calcium; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Indomethacin; Myocardial Contraction; Phospholipid Ethers; Platelet Activating Factor; Quinolinium Compounds; SRS-A; Thiazoles | 1987 |
Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119.
Topics: Animals; Cebus; Indomethacin; Lung; Macaca mulatta; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Thrombocytopenia; Thromboxane B2 | 1986 |
Pulmonary vascular response to platelet-activating factor in awake sheep and the role of cyclooxygenase metabolites.
Topics: Animals; Blood Pressure; Cell Aggregation; Indomethacin; Lymph; Male; Meclofenamic Acid; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Pulmonary Circulation; Pulmonary Wedge Pressure; Sheep; Vascular Resistance | 1986 |
Hemodynamic effects of PAF-acether.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Female; Hemodynamics; Indomethacin; Platelet Activating Factor; Renal Circulation; Saralasin; Sodium | 1986 |
Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit.
Topics: Adenosine Diphosphate; Animals; Collagen; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Thromboxane B2 | 1986 |
In vitro contractile effect of platelet-activating factor on guinea-pig myometrium.
Topics: Animals; Chromones; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Myometrium; Oxytocin; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins; Thiazoles; Uterine Contraction | 1986 |
A possible role of antihypertensive polar renomedullary lipid (APRL) and prostaglandin E2 in the kidney in the antihypertensive action of pindolol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dinoprostone; Electrolytes; Indomethacin; Kidney; Male; Phospholipid Ethers; Pindolol; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred SHR; Thiazoles | 1985 |
Platelet activating factor-stimulated formation of inositol triphosphate in platelets and its regulation by various agents including Ca2+, indomethacin, CV-3988, and forskolin.
Topics: Animals; Blood Platelets; Calcium; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Sugar Phosphates; Thiazoles; Time Factors | 1985 |
Cardiac, coronary and peripheral vascular effects of acetyl glyceryl ether phosphoryl choline in the anesthetized dog.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Blood Pressure; Coronary Circulation; Dogs; Extremities; Female; Heart; Heart Rate; Hexamethonium Compounds; Indomethacin; Male; Myocardial Contraction; Platelet Activating Factor; Pyrazoles; Regional Blood Flow; Theophylline; Vagotomy; Vasodilation | 1985 |
Characterization of cutaneous vascular permeability induced by platelet-activating factor in guinea pigs and rats and its inhibition by a platelet-activating factor receptor antagonist.
Topics: Animals; Benzofurans; Benzopyrans; Binding Sites; Bradykinin; Cell Membrane Permeability; Cyclooxygenase Inhibitors; Drug Interactions; Female; Guinea Pigs; Histamine; Indomethacin; Lignans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Skin; Species Specificity; Tritium | 1985 |
Production of platelet-activating factor by human vascular endothelial cells: evidence for a requirement for specific agonists and modulation by prostacyclin.
Topics: Cells, Cultured; Cyclooxygenase Inhibitors; Endothelium; Epoprostenol; Humans; Indomethacin; Platelet Activating Factor; Thrombin; Umbilical Cord; Veins | 1985 |
Stimulation of hepatic glycogenolysis by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) via cyclooxygenase products.
Topics: Acetophenones; Animals; Female; Glucose; Indomethacin; Liver Glycogen; Perfusion; Phorbols; Phospholipases A; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Parasympathetic stimulation as a mechanism for platelet-activating factor-induced contractile responses in the lung.
Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Parasympatholytics; Platelet Activating Factor; Tetrodotoxin | 1986 |
Response to platelet-activating factor of platelets from patients with multiple sclerosis.
Topics: Acetophenones; Blood Platelets; Calcium; Humans; Indomethacin; Multiple Sclerosis; Platelet Activating Factor; Platelet Aggregation; Verapamil | 1985 |
Unsaturated 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholines (unsaturated platelet-activating factor): aggregation of human platelets after incubation with indomethacin, creatinephosphate/creatinephosphokinase, xylocain and hirudine, and serotonin release
Topics: Blood Platelets; Creatine Kinase; Female; Hirudins; Humans; Indomethacin; Lidocaine; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1985 |
Functional and biochemical characterization of immunologically derived equine platelet-activating factor.
Topics: Animals; Antigens, Helminth; Ascaris; Aspirin; Blood Platelets; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Horses; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Leukocytes; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1985 |
Partial characterization of the embryo-derived platelet-activating factor in mice.
Topics: Animals; Chemical Phenomena; Chemistry; Chlorpromazine; Embryo, Mammalian; Female; Indomethacin; Kinetics; Mice; Phosphoenolpyruvate; Platelet Activating Factor | 1985 |
Pharmacological investigation of the mechanisms of platelet-activating factor induced mortality in the mouse.
Topics: Anaphylaxis; Animals; Chloroquine; Chlortetracycline; Dexamethasone; Dose-Response Relationship, Drug; Female; Indomethacin; Injections, Intravenous; Male; Mice; Mice, Inbred DBA; Naproxen; Nicardipine; Nifedipine; Platelet Activating Factor; Pyrazoles; Quinacrine; Tetracycline; Verapamil | 1985 |
Release of a slow-reacting substance from rabbit platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Platelets; Chromatography, High Pressure Liquid; Cysteine; Indomethacin; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1981 |
Inhibition of platelet adenylate cyclase by 1-O-alkyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine (platelet-activating factor).
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Creatine Kinase; Cyclic AMP; Indomethacin; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Prostaglandins E; Rabbits | 1982 |
Acetyl glycerylphosphorylcholine inhibition of prostaglandin I2-stimulated adenosine 3',5'-cyclic monophosphate levels in human platelets. Evidence for thromboxane A2 dependence.
Topics: Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1982 |
Neutrophil aggregating properties of PAF-acether and leukotriene B4.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Cell Aggregation; Dose-Response Relationship, Drug; Indomethacin; Leukotriene B4; Male; Masoprocol; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1983 |
Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis and cyclic AMP accumulation in human polymorphonuclear leukocytes.
Topics: Cell Aggregation; Cyclic AMP; Humans; Indomethacin; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor | 1983 |
Effects of a thio analog of platelet-activating factor on platelet aggregation and adenosine 3',5'-monophosphate concentration in hepatocyte suspensions and in platelets. A comparison with the naturally occurring compound.
Topics: Alprostadil; Animals; Blood Platelets; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Acetylglycerylether phosphorylcholine-(AGEPC) and leukotriene B4-stimulated cyclic AMP levels in human polymorphonuclear leukocytes.
Topics: Adenylyl Cyclases; Arachidonate Lipoxygenases; Cell Aggregation; Cyclic AMP; Cyclooxygenase Inhibitors; Epoprostenol; Feedback; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor | 1984 |
Shape change induced in human platelets by platelet-activating factor. Correlation with the formation of phosphatidic acid and phosphorylation of a 40,000-dalton protein.
Topics: Blood Platelets; Blood Proteins; Epoprostenol; Humans; Indomethacin; Microscopy, Electron, Scanning; Molecular Weight; Phosphatidic Acids; Phosphorylation; Platelet Activating Factor; Trifluoperazine | 1983 |
Stimulation of calcium uptake by 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) in rabbit platelets: possible involvement of the lipoxygenase pathway.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Blood Platelets; Calcium; Indomethacin; Platelet Activating Factor; Rabbits; Verapamil | 1983 |
Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine.
Topics: Amniotic Fluid; Arachidonic Acid; Arachidonic Acids; Calcium; Female; Humans; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Pregnancy | 1983 |
Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Enzyme Activation; Epinephrine; Humans; Indomethacin; Kinetics; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Thrombin; Trifluoperazine; Type C Phospholipases | 1984 |
Effects of nonsteroid antiinflammatory drugs on the specific binding of platelet activating factor to membrane preparations of rabbit platelets.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Blood Platelets; Cell Membrane; Cyclooxygenase Inhibitors; Indomethacin; Platelet Activating Factor; Rabbits | 1984 |
Bronchial anaphylaxis in actively sensitized Sprague Dawley rats: studies on mediators involved.
Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bronchi; Cyclooxygenase Inhibitors; Immunization; Indomethacin; Male; Methysergide; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; Vagotomy | 1984 |
Possible involvement of cyclooxygenase products in the actions of platelet-activating factor and of lipoxygenase products in the vascular effects of epinephrine in perfused rat liver.
Topics: Acetophenones; Angiotensin II; Animals; Epinephrine; Female; Indomethacin; Lipoxygenase; Liver; Liver Glycogen; Perfusion; Platelet Activating Factor; Propranolol; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Vasoconstriction | 1984 |
On the nature of the vasoreactivity depressing factor (VDF) in inflammation and anaphylaxis in the rat and mouse.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprostadil; Anaphylaxis; Animals; Anti-Inflammatory Agents; Epoprostenol; Female; Histamine; Indomethacin; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; Serotonin; Vasopressins | 1984 |
A pharmacologic analysis of the action of platelet-activating factor in the induction of hindpaw edema in the rat.
Topics: Animals; Carrageenan; Dexamethasone; Dose-Response Relationship, Drug; Edema; Hindlimb; Indomethacin; Male; Muscles; Phentolamine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline; Verapamil; Yohimbine | 1984 |
PAF-acether-induced plasma exudation in rat skin is independent of platelets and neutrophils.
Topics: Animals; Blood Platelets; Blood Proteins; Capillary Permeability; Indomethacin; Male; Methysergide; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains; Skin | 1984 |
Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution.
Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Blood Platelets; Female; Guinea Pigs; Indomethacin; Lung; Perfusion; Platelet Activating Factor; Pressure; Pulmonary Edema; Thromboxane B2; Vascular Resistance | 1984 |
Platelet-activating factor stimulation of peptidoleukotriene release: inhibition by vasoactive polypeptide.
Topics: Animals; Dinoprostone; Indomethacin; Lung; Male; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; SRS-A; Vasoactive Intestinal Peptide | 1984 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
Enhancement of human polymorphonuclear leukocyte adherence by the phospholipid mediator 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (AGEPC).
Topics: Adult; Cell Adhesion; Dose-Response Relationship, Drug; Humans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Thromboxane A2 | 1983 |
1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholines: influence on aggregation and [3H]serotonin release of human thrombocytes.
Topics: Blood Platelets; Hirudins; Humans; Indomethacin; Kinetics; Lidocaine; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1983 |
1-O-hexadecyl-2-acetyl-sn-3-glycerophosphorylcholine (PAF): some effects on the aggregation of human platelets by thrombin or collagen.
Topics: Collagen; Dose-Response Relationship, Drug; Humans; Indomethacin; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1983 |
Glucocorticoid protection against PAF-acether toxicity in mice.
Topics: Animals; Cortisone; Female; Glucocorticoids; Indomethacin; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Sex Factors; Verapamil | 1983 |
Acute microvascular effects of PAF-acether, as studied by intravital microscopy.
Topics: Animals; Cheek; Cricetinae; Extravasation of Diagnostic and Therapeutic Materials; Indomethacin; Injections, Intravenous; Male; Mesocricetus; Microcirculation; Neutropenia; Platelet Activating Factor; Vasoconstriction | 1983 |
Effect of platelet-activating factor on coronary circulation of the domestic pig.
Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Female; Heart Rate; Indomethacin; Male; Platelet Activating Factor; Swine; Vascular Resistance | 1984 |
Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Edema; Hyperalgesia; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Rats | 1981 |
Release of PAF by human polymorphonuclear leucocytes stimulated by immune complexes bound to Sepharose particles and human erythrocytes.
Topics: Animals; Antigen-Antibody Complex; Erythrocytes; Humans; Indomethacin; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Zymosan | 1983 |
Effect of platelet-activating factor (PAF) on human platelets.
Topics: Animals; Antimycin A; Aspirin; Blood Platelets; Cattle; Creatine Kinase; Deoxyglucose; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin | 1982 |
Nonimmunological production of leukotrienes induced by platelet-activating factor.
Topics: Animals; Chromatography, High Pressure Liquid; Indomethacin; Lung; Male; Platelet Activating Factor; Rats; SRS-A; Vasoconstriction | 1982 |
Variable responses of human platelets to synthetic platelet activating factor and their modification by epinephrine.
Topics: Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Indomethacin; Male; Phentolamine; Platelet Activating Factor; Platelet Aggregation | 1982 |
Thrombin-induced formation of a polar lipid material within platelets that possesses platelet-activating activity.
Topics: Adenosine Diphosphate; Animals; Apyrase; Arachidonic Acids; Blood Platelets; Cattle; Indomethacin; Lipids; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1980 |
The presence of platelet-activating factor (PAF) in normal human mixed saliva.
Topics: Adenosine Diphosphate; Adult; Animals; Arachidonic Acids; Creatine Kinase; Dose-Response Relationship, Immunologic; Female; Hirudins; Humans; Indomethacin; Lysophosphatidylcholines; Male; Middle Aged; Platelet Activating Factor; Rabbits; Saliva; Serotonin; Thrombin | 1981 |
Platelet-activating factor-induced loss of vascular responsiveness to noradrenaline in pithed rats: involvement of nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Cyclooxygenase Inhibitors; Decerebrate State; Enzyme Inhibitors; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Platelet Activating Factor; Rats; Rats, Wistar; Vasomotor System | 1995 |
Effects of prostaglandin of E, F and I series, leukotriene C and platelet activating factor on amylase release from isolated rat pancreatic acini.
Topics: Acetamides; Amylases; Animals; Bethanechol Compounds; Ceruletide; Chromones; Dinoprostone; Epoprostenol; Indomethacin; Isoquinolines; Leukotriene C4; Male; Pancreas; Phenyl Ethers; Platelet Activating Factor; Prostaglandin Antagonists; Prostaglandins; Prostaglandins F; Prostaglandins F, Synthetic; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines | 1993 |
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections | 1993 |
Role of eicosanoids but not nitric oxide in the platelet-activating factor-induced increase in vascular permeability in mouse skin.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Capillary Permeability; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Skin | 1995 |
Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Adhesion; Dinoprostone; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Indomethacin; Leukocytes; Leukotriene C4; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfhydryl Compounds; Tetrazoles; Thiophenes | 1995 |
Effect of ibudilast on ciliary activity of human paranasal sinus mucosa in vitro.
Topics: Bronchodilator Agents; Cilia; Humans; In Vitro Techniques; Indomethacin; Leukotriene D4; Mucociliary Clearance; Nasal Mucosa; Paranasal Sinuses; Platelet Activating Factor; Propranolol; Pyridines; Verapamil | 1995 |
Possible role of platelet-activating factor in embryonic signaling during oviductal transport in the hamster.
Topics: Animals; Cricetinae; Culture Techniques; Diterpenes; Embryo, Mammalian; Female; Ginkgolides; Indomethacin; Isoquinolines; Lactones; Masoprocol; Ovum Transport; Platelet Activating Factor; Platelet Count; Pregnancy; Pyridinium Compounds; Signal Transduction; Tetrahydroisoquinolines | 1995 |
Inhaled nitric oxide reverses PAF-dependent bronchoconstriction in the pig.
Topics: Administration, Inhalation; Airway Resistance; Animals; Blood Pressure; Bronchoconstriction; Female; Indomethacin; Lung; Male; Nitric Oxide; Platelet Activating Factor; Swine; Tidal Volume; Vasodilation | 1995 |
Platelets enhance anoxic contraction of rat aortic rings through platelet-activating factor-dependent mechanism.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Buffers; Endothelium, Vascular; Free Radical Scavengers; Humans; Hypoxia; In Vitro Techniques; Indicators and Reagents; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1993 |
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Interleukin-1; Male; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Receptors, Interleukin-1; Receptors, Neurokinin-1; Regional Blood Flow; Substance P; Xenon Radioisotopes | 1993 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Increased prostaglandin I2 and thromboxane A2 production by rat dental pulp after intravenous administration of endotoxin.
Topics: Animals; Arachidonic Acid; Azepines; Dental Pulp; Endotoxins; Epoprostenol; Escherichia coli; Indomethacin; Injections, Intravenous; Jejunum; Lung; Male; Platelet Activating Factor; Rats; Rats, Wistar; Thromboxane A2; Time Factors; Triazoles | 1994 |
Mediators of the ocular inflammatory response to interleukin-1 beta plus tumor necrosis factor-alpha.
Topics: Animals; Indomethacin; Interleukin-1; Male; Platelet Activating Factor; Rabbits; Tumor Necrosis Factor-alpha; Uveitis, Anterior; Uveitis, Posterior | 1995 |
Platelet activating factor induces transformation of human fibroblasts.
Topics: Alkaloids; Analysis of Variance; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Genistein; Growth Inhibitors; Humans; Indomethacin; Infant, Newborn; Isoflavones; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Skin; Staurosporine | 1995 |
Desensitization of platelet-activating factor receptors, induced by inflammation in guinea pig ileal smooth muscle cells.
Topics: Acetylcholine; Animals; Cell Survival; Dinoprostone; Diterpenes; Ginkgolides; Guinea Pigs; Ileitis; Ileum; Indomethacin; Lactones; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E; Trinitrobenzenesulfonic Acid | 1995 |
Effects of tenidap on leukocyte-endothelial cell adhesion in mesenteric venules.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Endothelium, Vascular; Indoles; Indomethacin; Leukocytes; Leukotriene Antagonists; Male; Oxindoles; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Venules | 1995 |
Protective effect of propionyl-L-carnitine against PAF-induced rat paw oedema.
Topics: Animals; Cardiotonic Agents; Carnitine; Carrageenan; Dose-Response Relationship, Drug; Edema; Indomethacin; Male; Phenylbutazone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Studies on the mechanism of PAF-induced vasopermeability in rat lungs.
Topics: Animals; Blood Proteins; Bronchi; Capillary Permeability; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Imidazoles; Indomethacin; Lung; Male; Platelet Activating Factor; Quinacrine; Rats; Rats, Wistar; Trachea | 1995 |
Three drugs inhibit phospholipase A2-induced high permeability of endothelial monolayers.
Topics: Animals; Calcitriol; Capillary Permeability; Endothelium, Vascular; Female; Indomethacin; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Sprague-Dawley | 1994 |
Homologous desensitization of PAF receptors via a PGE2-dependent pathway on intestinal smooth muscle.
Topics: Acetophenones; Animals; Dinoprostone; Guinea Pigs; Ileum; Indomethacin; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E; Sensitivity and Specificity; Sincalide; Time Factors | 1994 |
In pigs, inhaled nitric oxide (NO) counterbalances PAF-induced pulmonary hypertension.
Topics: Administration, Inhalation; Animals; Arginine; Blood Pressure; Female; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pulmonary Artery; Swine; Vasoconstriction | 1994 |
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Cells; Blood Pressure; Cardiac Output; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypotension; Indomethacin; Injections, Intravenous; Leukopenia; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Starfish; Tachyphylaxis; Thrombocytopenia; Vascular Resistance; Venoms | 1994 |
Characterization of platelet-activating factor synthesis in glomerular endothelial cell lines.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Animals; Cattle; Cell Line, Transformed; Cells, Cultured; Endothelins; Endothelium, Vascular; Glomerular Mesangium; Indomethacin; Kidney Glomerulus; Phospholipases A; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Thrombin | 1994 |
Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arginine; Aspartic Acid; Female; Flavanones; Flavonoids; gamma-Aminobutyric Acid; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Indomethacin; Masoprocol; omega-N-Methylarginine; Platelet Activating Factor; Potassium; Prostaglandin-Endoperoxide Synthases; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Taurine | 1995 |
The effect of Clostridium difficile toxin on colonocyte prostanoid activity.
Topics: 6-Ketoprostaglandin F1 alpha; Bacterial Proteins; Bacterial Toxins; Cell Line, Transformed; Colon; Culture Media; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Humans; Indomethacin; Leukotriene B4; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane B2 | 1994 |
Assessment of agonist- and cell-mediated responses in airway microsections by computerized videomicrometry.
Topics: Acetylcholine; Animals; Computers; Eosinophils; Epithelium; Guinea Pigs; Humans; Indomethacin; Kinetics; Male; Microscopy, Video; Miniaturization; Muscle Contraction; Platelet Activating Factor; Receptors, Adrenergic, beta; Trachea | 1995 |
Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema.
Topics: Ajmaline; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Carbon Radioisotopes; Carrageenan; Edema; Humans; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Shock | 1993 |
Protective effects of somatostatin against gastric damage induced by hemorrhagic shock, stress and PAF in the rat.
Topics: Animals; Endotoxins; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Shock, Hemorrhagic; Somatostatin; Stomach; Stomach Diseases; Stress, Physiological | 1993 |
Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin.
Topics: Animals; CHO Cells; Cholera Toxin; Cricetinae; Cytoskeleton; Diterpenes; Epithelium; Ginkgolides; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles | 1994 |
IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Gene Expression Regulation; GTP-Binding Proteins; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Leukotriene D4; Lipids; Lipoxygenase Inhibitors; Masoprocol; Muscle, Smooth; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Recombinant Proteins; Thromboxane A2; Trachea; Vasoconstrictor Agents | 1994 |
WEB-2086 and indomethacin do not modify blood pressure fall on unclipping hypertensive rats.
Topics: Animals; Azepines; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Indomethacin; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Wistar; Renal Artery; Triazoles | 1994 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
ADP-, PAF- and adrenaline-induced platelet aggregation and thromboxane formation are not affected by a thromboxane receptor antagonist at physiological external Ca++ concentrations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Citric Acid; Collagen; Epinephrine; Glucose; Hirudins; Humans; Indomethacin; Phenylacetates; Platelet Activating Factor; Platelet Aggregation; Receptors, Thromboxane; Recombinant Proteins; Sulfonamides; Thromboxanes | 1994 |
The production of experimental cholecystitis by endotoxin.
Topics: Alprazolam; Animals; Cats; Cholecystitis; Gallbladder; Indomethacin; Lipopolysaccharides; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1994 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Hyperalgesia induced by Bothrops jararaca venom in rats: role of eicosanoids and platelet activating factor (PAF).
Topics: Animals; Azepines; Bothrops; Crotalid Venoms; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Fibrinolytic Agents; Ginkgolides; Hyperalgesia; Indomethacin; Lactones; Male; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles | 1994 |
Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids.
Topics: Animals; Arachidonic Acid; Benzoquinones; Constriction, Pathologic; Drug Synergism; Indomethacin; Leukotriene C4; Lipoxygenase Inhibitors; Male; Organ Size; Platelet Activating Factor; Premedication; Prostaglandins F; Protamines; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Thromboxane B2; Vascular Resistance | 1994 |
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Culture Techniques; Edetic Acid; Eicosanoids; Ileum; Indomethacin; Kinetics; Leukotriene B4; Leukotriene D4; Male; Permeability; Platelet Activating Factor; Rats; Rats, Wistar | 1994 |
Rat gastric motor response to food protein-induced anaphylaxis.
Topics: Albumins; Anaphylaxis; Animals; Dietary Proteins; Gastrointestinal Motility; Histamine Antagonists; Indomethacin; Lipoxygenase Inhibitors; Mast Cells; Muscle Contraction; Ovum; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stomach; Tetrodotoxin | 1994 |
Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats.
Topics: Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cricetinae; Indomethacin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Lung; Lung Diseases; Male; Organ Size; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thromboxane A2; Time Factors; Tumor Necrosis Factor-alpha | 1993 |
Pharmacological characterization of WAY-121,520: a potent anti-inflammatory indomethacin-based inhibitor of 5-lipoxygenase (5-LO)/phospholipase A2 (PLA2).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoconstriction; Edema; Guinea Pigs; Humans; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandins E; Quinolines | 1993 |
Involvement of protein kinase C in the control of microvascular permeability to colloidal carbon.
Topics: Animals; Capillary Permeability; Carbon; Colloids; Cyclooxygenase Inhibitors; In Vitro Techniques; Indoles; Indomethacin; Intestinal Absorption; Platelet Activating Factor; Protein Kinase C; Rats; Serotonin; Serotonin Antagonists | 1993 |
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor].
Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; Isoquinolines; Nifedipine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pregnancy; Pyridinium Compounds; Rats; Tetrahydroisoquinolines; Uterine Contraction | 1994 |
Stimulation of development of in vitro-matured and in vitro-fertilized bovine embryos by platelets.
Topics: Animals; Blood Platelets; Cattle; Cells, Cultured; Culture Media; Embryonic and Fetal Development; Fallopian Tubes; Female; Fertilization in Vitro; Indomethacin; Mianserin; Platelet Activating Factor; Platelet-Derived Growth Factor; Prostaglandins; Serotonin | 1993 |
Role of endothelin and platelet-activating factor in indomethacin-induced gastric mucosal injury in rats.
Topics: Animals; Endothelins; Gastric Mucosa; Gastritis; Immunization, Passive; Indomethacin; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley | 1993 |
Prostaglandin F2 alpha mediates platelet-activating factor-stimulated atrial natriuretic factor release from the isolated rat heart.
Topics: Animals; Atrial Natriuretic Factor; Dinoprost; Dinoprostone; Heart; Heart Rate; Indomethacin; Kinetics; Male; Meclofenamic Acid; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins E; Prostaglandins F; Rats | 1993 |
Mediators of the hypotensive response to increased renal perfusion in rabbits.
Topics: Animals; Azepines; Blood Pressure; Diuresis; Enalaprilat; Hemodynamics; Hypotension; Indomethacin; Natriuresis; Perfusion; Platelet Activating Factor; Pressure; Rabbits; Renal Circulation; Triazoles | 1993 |
Bronchopulmonary responses to endothelin-1 in sensitized and challenged guinea-pigs: role of cyclooxygenase metabolites and platelet-activating factor.
Topics: Aerosols; Animals; Azepines; Bronchi; Disease Models, Animal; Endothelins; Glycopeptides; Guinea Pigs; Immunization; Indomethacin; Lung; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory Function Tests; Tetrazoles; Thienopyridines; Time Factors; Triazoles | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung.
Topics: Animals; Arachidonic Acids; Benzoquinones; Blood Pressure; Bronchoconstriction; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indicators and Reagents; Indomethacin; Interferon Inducers; Interferon Type I; Lipoxygenase Inhibitors; Lung Diseases; Male; Microcirculation; Platelet Activating Factor; Poly I-C; Pulmonary Edema; Rabbits; Recombinant Proteins; Vascular Resistance | 1993 |
Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs.
Topics: Animals; Blood Platelets; Calcimycin; GTP-Binding Proteins; Hemodynamics; Indomethacin; Injections, Intravenous; Lung; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sodium Chloride; Swine; Thrombocytopenia; Thromboxane B2; Time Factors; Vasoconstriction; Virulence Factors, Bordetella | 1993 |
Biochemical evidence of platelet-activating factor (PAF) in human middle ear effusions.
Topics: Arachidonic Acids; Humans; Indomethacin; Otitis Media with Effusion; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation | 1995 |
Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antibodies; Cells, Cultured; Cholecystitis; Cytochrome P-450 Enzyme System; Dinoprost; Dose-Response Relationship, Drug; Epoprostenol; Gallbladder; Immunoblotting; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Proteins; Rabbits; Thromboxane B2 | 1995 |
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Ibuprofen; Indomethacin; Macrophages, Peritoneal; Male; Naproxen; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
Platelet-activating factor production in stimulated macrophages is down-regulated by concurrently produced prostaglandin E2.
Topics: Animals; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Indomethacin; Macrophages; Male; Platelet Activating Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1996 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |
Involvement of platelet cyclic GMP but not cyclic AMP suppression in leukocyte-dependent platelet adhesion to endothelial cells induced by platelet-activating factor in vitro.
Topics: Animals; Blood Platelets; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Methylene Blue; Neutrophils; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Adhesiveness; Purinones; Rabbits | 1996 |
Inhibitory effect of arachidonic acid on platelet-activating factor production in rat neutrophils.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazenes; Zymosan | 1996 |
Biochemical and cellular effects of heparin-protamine injection in rabbits are partially inhibited by a PAF-acether receptor antagonist.
Topics: Animals; Anticoagulants; Cyclooxygenase Inhibitors; Diterpenes; Fibrinolytic Agents; Ginkgolides; Heparin; Heparin Antagonists; Indomethacin; Infusions, Intravenous; Lactones; Platelet Activating Factor; Protamines; Rabbits; Thromboxane B2 | 1996 |
Involvement of nitric oxide and eicosanoids in platelet-activating factor-induced haemodynamic and haematological effects in dogs.
Topics: Animals; Benzoquinones; Biphenyl Compounds; Cell Count; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Eicosanoids; Female; Heptanoic Acids; Hypotension; Indomethacin; Isoquinolines; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Pyridinium Compounds; Tetrahydroisoquinolines; Vascular Resistance | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Thromboxane rather than platelet activating factor mediates pulmonary vasoconstriction after antigen challenge in rabbits.
Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Enzyme Inhibitors; Humans; Immunization; Indomethacin; Lung; Methacrylates; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Pyridinium Compounds; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction | 1996 |
Effect of lipoxygenase inhibition on mucous glycoprotein secretion from chinchilla middle ear epithelial cells in vitro.
Topics: Acetamides; Animals; Arachidonic Acid; Cells, Cultured; Chinchilla; Cyclooxygenase Inhibitors; Ear, Middle; Epithelium; Glycoproteins; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Phenyl Ethers; Platelet Activating Factor | 1996 |
Regulation of platelet-activating factor receptor gene expression in vivo by endotoxin, platelet-activating factor and endogenous tumour necrosis factor.
Topics: Animals; Blood Pressure; Hematocrit; Ileum; Indomethacin; Lipopolysaccharides; Male; Mutagenesis, Site-Directed; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA-Directed DNA Polymerase; RNA, Complementary; RNA, Messenger; Tissue Distribution; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
PAF modulates eicosanoids and TNF release in immune-complex arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthus Reaction; Cattle; Dinoprostone; Eicosanoids; Indoles; Indomethacin; Injections, Intra-Articular; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Wistar; Synovial Fluid; Thromboxane B2; Tumor Necrosis Factor-alpha | 1997 |
Platelet-activating factor production in the stimulated macrophages is enhanced by the cyclooxygenase inhibitors.
Topics: Animals; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Macrophages; Macrophages, Peritoneal; Platelet Activating Factor; Rats; Stimulation, Chemical; Thapsigargin | 1996 |
Platelet-activating factor. A possible role in the modulation of the vasomotor tone and blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Pressure; Carotid Arteries; Diterpenes; Enzyme Inhibitors; Ginkgolides; Indomethacin; Lactones; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinacrine; Rabbits; Triazoles | 1996 |
Role of synergistic action of PAF and kinin in bacterial endotoxin-induced hypotension in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bradykinin; Dexamethasone; Drug Synergism; Hypotension; Indomethacin; Injections, Intravenous; Kininogens; Kinins; Lipopolysaccharides; Platelet Activating Factor; Rats; Rats, Inbred BN | 1996 |
2',5'-Dihydroxychalcone as a potent chemical mediator and cyclooxygenase inhibitor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Chalcone; Chalcones; Cyclooxygenase Inhibitors; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Structure-Activity Relationship; Thrombin | 1997 |
Clostridium difficile toxin A induces the release of neutrophil chemotactic factors from rat peritoneal macrophages: role of interleukin-1beta, tumor necrosis factor alpha, and leukotrienes.
Topics: Animals; Bacterial Toxins; Chemotaxis, Leukocyte; Clostridioides difficile; Diterpenes; Enterotoxins; Female; Ginkgolides; Indomethacin; Interleukin-1; Interleukin-8; Lactones; Leukotrienes; Macrophages, Peritoneal; Male; Platelet Activating Factor; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1997 |
Effect of endotoxin and platelet-activating factor on rat vascular permeability: role of vasoactive mediators.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Capillary Permeability; Dose-Response Relationship, Drug; Exudates and Transudates; Imidazoles; Indomethacin; Leucine; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Piperazines; Platelet Activating Factor; Pyrazoles; Rats; Rats, Sprague-Dawley | 1997 |
cAMP mediates homologous downregulation of PAF receptor mRNA expression in mesangial cells.
Topics: Animals; Azepines; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Female; Glomerular Mesangium; Indomethacin; Kinetics; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Transcription, Genetic; Triazoles; Virulence Factors, Bordetella | 1997 |
Airway responsiveness in transgenic mice overexpressing platelet-activating factor receptor. Roles of thromboxanes and leukotrienes.
Topics: Animals; Azepines; Bronchi; Bronchial Hyperreactivity; Chromones; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Lung; Methacrylates; Mice; Mice, Transgenic; Phenylpropionates; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Thromboxanes; Triazoles | 1997 |
[Effect of platelet activating factor on TxA2, PGI2 and Ca(2+)-ATPase activity in the intra-pulmonary artery smooth muscle cells].
Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Epoprostenol; Indomethacin; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Rabbits; Thromboxane A2; Verapamil | 1996 |
Pulmonary and neutrophil responses to priming effects of platelet-activating factor in pigs.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Blood Gas Analysis; Blood Pressure; Carcinogens; Cyclooxygenase Inhibitors; Indomethacin; Lipopolysaccharides; Neutrophils; Platelet Activating Factor; Random Allocation; Respiratory Physiological Phenomena; Respiratory System; Superoxides; Swine; Tetradecanoylphorbol Acetate; Time Factors; Vascular Resistance | 1997 |
Receptor-mediated and protein kinase-dependent growth enhancement of primary human fibroblasts by platelet activating factor.
Topics: Animals; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Genistein; Humans; Indomethacin; Infant, Newborn; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepharose; Skin; Staurosporine; Transcription, Genetic; Up-Regulation | 1997 |
Nitric oxide mediates platelet-activating factor stimulatory action on uterine prostaglandin production.
Topics: Animals; Arachidonic Acid; Citrulline; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; Enzyme Inhibitors; Female; Gestational Age; Indomethacin; Isometric Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Pregnancy; Prostaglandins; Rats; Rats, Wistar; Uterus | 1998 |
Role of nitric oxide and platelet-activating factor in the initiation of indomethacin-provoked intestinal inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enteritis; Ileum; Indomethacin; Jejunum; Male; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar | 1998 |
The role of platelet-activating factor in cell infiltration in endotoxin-induced uveitis in guinea pigs.
Topics: Animals; Anterior Chamber; Aqueous Humor; Azepines; Betamethasone; Chemotaxis, Leukocyte; Dinoprostone; Escherichia coli; Flow Cytometry; Guinea Pigs; Indomethacin; Leukocyte Count; Leukocytes; Lipopolysaccharides; Male; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles; Uveitis, Anterior | 1998 |
On the mechanisms of adenosine induced pulmonary vasoconstriction in rats.
Topics: Adenosine; Adrenergic Antagonists; Animals; Cyclooxygenase Inhibitors; Cyproheptadine; Dihydroergotoxine; Endothelium, Vascular; Female; Flavonoids; Ginkgo biloba; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Plant Extracts; Platelet Activating Factor; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Quinidine; Rats; Rats, Sprague-Dawley; Theophylline; Vasoconstriction | 1997 |
Tumour necrosis factor-alpha induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.
Topics: Airway Resistance; Animals; Azepines; Bronchial Hyperreactivity; Culture Techniques; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Muscle, Smooth; Platelet Activating Factor; Platelet Aggregation Inhibitors; Recombinant Proteins; Triazoles; Tumor Necrosis Factor-alpha | 1998 |
Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Dronabinol; Endocannabinoids; Immune System; Indomethacin; Ionophores; Lipopolysaccharides; Macrophages; Mice; Platelet Activating Factor; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug | 1998 |
Modulation by lipid mediators of immune complex-induced lung inflammation in mice.
Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Azepines; Benzopyrans; Blood Vessels; Bronchoalveolar Lavage Fluid; Capillary Permeability; Dose-Response Relationship, Drug; Eicosanoids; Hemoglobins; Immune Complex Diseases; Indoles; Indomethacin; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pneumonia; Receptors, Leukotriene B4; Species Specificity; Triazoles | 1998 |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase | 1999 |
Microvascular permeability change induced by platelet-activating factor is impaired in diabetic mice.
Topics: Animals; Azo Compounds; Capillary Permeability; Coloring Agents; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Glycoconjugates; Guanidines; Hypoglycemic Agents; Indomethacin; Insulin; Male; Methylene Blue; Mice; Mice, Mutant Strains; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Platelet Activating Factor; Skin; Streptozocin; Trypan Blue | 1999 |
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages.
Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle.
Topics: Action Potentials; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Azepines; Cyclooxygenase Inhibitors; Depression, Chemical; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Propranolol; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Interaction between platelet-aggregating response and vasoconstrictive response to platelet activating factor.
Topics: Animals; Arteries; Blood Platelets; Bucladesine; Collagen; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Norepinephrine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Vasoconstriction | 1999 |
Regulation of immunoglobulin G2 production by prostaglandin E(2) and platelet-activating factor.
Topics: Aggressive Periodontitis; Cells, Cultured; Dinoprostone; Humans; Immunoglobulin G; Indomethacin; Macrophages; Monocytes; Phospholipid Ethers; Platelet Activating Factor | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors.
Topics: Arachidonate 5-Lipoxygenase; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Solubility; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arginine; Blood Pressure; Cardiac Output; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Rate; Histamine; Indomethacin; Isoenzymes; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Ventilation; Serotonin; Signal Transduction; Sulfonamides | 2001 |
Participation of prostaglandin E2 and platelet-activating factor in thapsigargin-induced production of interleukin-6.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Animals; Azepines; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Interleukin-6; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thapsigargin; Triazoles | 2002 |
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
Topics: Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Flavonoids; Humans; In Vitro Techniques; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Pyrrolidinones; Serotonin; Thromboxane A2; Verapamil | 2001 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation.
Topics: Benzoquinones; Blood Platelets; Calcimycin; Humans; Indomethacin; Ionophores; Lactams, Macrocyclic; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Thromboxane A2; Verapamil | 2004 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Edema; Foot; Hindlimb; Histamine; Indomethacin; Injections, Intraperitoneal; Leukocytes; Lipoxins; Male; Mice; Neutrophil Infiltration; Oligopeptides; Platelet Activating Factor; Pleurisy; Receptors, Lipoxin | 2006 |
Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Complement C3; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Elapid Venoms; Epoprostenol; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Zymosan | 2008 |
Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Motifs; Animals; Apoptosis; Arachidonic Acid; Caspase 3; Cell Line; Chromones; Docosahexaenoic Acids; Enzyme Inhibitors; Epithelial Cells; Fatty Acids, Unsaturated; Gene Expression; Indomethacin; Intestines; Lipoylation; Models, Biological; Morpholines; Oncogene Protein v-akt; Palmitates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Rats | 2008 |
Inhibition of human platelet aggregation by eosinophils.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Chromatography, Gel; Collagen; Cytosol; Dextrans; Eosinophils; HL-60 Cells; Humans; Indomethacin; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Wistar; Thrombin; Time Factors | 2013 |