Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and iloprost

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with iloprost in 22 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(iloprost)
Trials
(iloprost)
Recent Studies (post-2010) (iloprost)
9,1561875522,150271462

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)iloprost (IC50)
Prostacyclin receptorHomo sapiens (human)0.0112

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's11 (50.00)18.2507
2000's1 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giessler, C; Mentz, G; Mentz, P; Mest, HJ1
O'Neill, C; Ryan, JP; Spinks, NR1
Becker, K; Förster, W; Herfurth, ML; Schillinger, E1
Furman, BL; Gray, GA; Parratt, JR1
FitzGerald, GA; Murray, R; Shipp, E1
Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Schröder, H; Till, U1
Arner, M; Högestätt, ED1
Anderson, GP; Hultkvist-Bengtsson, U; Morley, J1
Ammit, AJ; Fleming, S; Korth, R; O'Neill, C; Wells, X1
O'Neill, C; Spinks, NR2
Addonizio, VP; Berkowitz, HD; Cottrell, ED; Ellison, N; Fisher, CA; Kappa, JR; Sobel, M1
Hecker, G; König, E; Ney, P; Schrör, K1
Beijer, L; Botting, J; Crook, P; Oyekan, AO; Page, CP; Rylander, R1
Belch, JJ; Forbes, CD; Saniabadi, AR1
Ney, P; Schrör, K1
Hecker, G; Ney, P; Schröder, H; Schrör, K1
Filipponi, F; Houssin, D; Michel, A1
Archer, CB; Frohlich, W; MacDonald, DM; Morley, J; Page, CW; Paul, W1
Alessio, P; Bussolino, F; Calvino, R; Fruttero, R; Gasco, A; Ghigo, D; Heller, R; Pescarmona, G; Till, U; Todde, R1
Hellewell, PG; Teixeira, MM; Williams, TJ1
Akkerman, JW; den Dekker, E; Gorter, G; Heemskerk, JW; van der Vuurst, H1

Other Studies

22 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and iloprost

ArticleYear
Interactions of prostanoids with the platelet activating factors.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 47, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Guinea Pigs; Heart; Iloprost; In Vitro Techniques; Indomethacin; Myocardial Contraction; Perfusion; Platelet Activating Factor; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxane B2; Triazoles

1992
Antagonists of embryo-derived platelet-activating factor act by inhibiting the ability of the mouse embryo to implant.
    Journal of reproduction and fertility, 1990, Volume: 88, Issue:1

    Topics: Animals; Azepines; Blastocyst; Decidua; Embryo Implantation; Embryo Transfer; Epoprostenol; Female; Iloprost; Mice; Mice, Inbred Strains; Platelet Activating Factor; Pregnancy; Quinolinium Compounds; Triazines; Triazoles; Trophoblasts

1990
Influence of some prostaglandins and prostaglandin analogues on PAF-induced shock in mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 40, Issue:2

    Topics: Animals; Cell Survival; Epoprostenol; Female; Iloprost; Mice; Platelet Activating Factor; Prostaglandins; Prostaglandins, Synthetic; Shock

1990
Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites.
    Circulatory shock, 1990, Volume: 31, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Endotoxins; Epoprostenol; Flurbiprofen; Hemodynamics; Iloprost; Male; Norepinephrine; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Spinal Cord; Sympathetic Nervous System

1990
Prostaglandin endoperoxide/thromboxane A2 receptor desensitization. Cross-talk with adenylate cyclase in human platelets.
    The Journal of biological chemistry, 1990, Dec-15, Volume: 265, Issue:35

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Iloprost; In Vitro Techniques; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombin; Thromboxane A2; Type C Phospholipases

1990
Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells.
    Biochimica et biophysica acta, 1991, Jun-07, Volume: 1093, Issue:1

    Topics: Acetyltransferases; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Iloprost; Ionomycin; Kinetics; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin

1991
Endothelium-dependent relaxation and effects of prostacyclin, endothelin and platelet-activating factor in human hand veins and arteries.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Arteries; Calcimycin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Epoprostenol; Female; Hand; Humans; Iloprost; Indomethacin; Male; Middle Aged; Platelet Activating Factor; Vasodilation; Veins

1991
Intrathoracic accumulation of 111In-labeled neutrophils in guinea pigs in response to PAF.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 70, Issue:6

    Topics: Animals; Blood Platelets; Cell Adhesion; Cell Movement; Guinea Pigs; Iloprost; Kinetics; Lung; Male; Neutrophils; Platelet Activating Factor; Thorax

1991
The effect of inhibitors of platelet aggregation on the metabolism of platelet-activating factor (PAF) in washed rabbit platelets.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Blood Platelets; Chromatography, High Pressure Liquid; Iloprost; Kinetics; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolinium Compounds; Rabbits; Triazoles; Tritium

1991
Embryo-deprived platelet-activating factor is essential for establishment of pregnancy in the mouse.
    Lancet (London, England), 1987, Jan-10, Volume: 1, Issue:8524

    Topics: Animals; Embryo Implantation; Embryo, Mammalian; Epoprostenol; Female; Humans; Iloprost; Mice; Platelet Activating Factor; Pregnancy; Pregnancy, Animal; Quinolinium Compounds; Time Factors

1987
Carotid endarterectomy in patients with heparin-induced platelet activation: comparative efficacy of aspirin and iloprost (ZK36374).
    Journal of vascular surgery, 1987, Volume: 5, Issue:5

    Topics: Aged; Aspirin; beta-Thromboglobulin; Cardiovascular Agents; Carotid Arteries; Drug Evaluation; Endarterectomy; Epoprostenol; Fibrinopeptide A; Heparin; Humans; Iloprost; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Factor 4; Preoperative Care; Thrombosis

1987
Potent inhibition of PAF-stimulated human platelets and polymorphonuclear leukocytes by the PGE1 analog OP-1206.
    Progress in clinical and biological research, 1987, Volume: 242

    Topics: Alprostadil; Blood Platelets; Epoprostenol; Humans; Iloprost; Kinetics; Neutrophils; Platelet Activating Factor; Platelet Aggregation

1987
The involvement of platelet activating factor in endotoxin-induced pulmonary platelet recruitment in the guinea-pig.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Blood Platelets; Endotoxins; Epoprostenol; Female; Guinea Pigs; Heparin; Iloprost; In Vitro Techniques; Indomethacin; Lung; Male; Platelet Activating Factor

1987
Whole blood white cell aggregation: a novel technique.
    Thrombosis research, 1987, Dec-15, Volume: 48, Issue:6

    Topics: Adult; Calcimycin; Cell Aggregation; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor

1987
Antagonists of embryo-derived platelet-activating factor prevent implantation of mouse embryos.
    Journal of reproduction and fertility, 1988, Volume: 84, Issue:1

    Topics: Alprazolam; Animals; Capillary Permeability; Embryo Implantation; Epoprostenol; Estradiol; Female; Iloprost; Mice; Platelet Activating Factor; Progesterone; Quinolinium Compounds; Uterus

1988
E-type prostaglandins but not iloprost inhibit platelet activating factor-induced generation of leukotriene B4 by human polymorphonuclear leukocytes.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: Arachidonic Acids; Cardiovascular Agents; Chromatography, High Pressure Liquid; Epoprostenol; Humans; Iloprost; Leukotriene B4; Neutrophils; Platelet Activating Factor; Prostaglandins E

1989
Potent inhibition of leukotriene (LT) B4 release from human polymorphonuclear leukocytes (PMN) by the PGE1-analogue OP-1206.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Alprostadil; Dinoprostone; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Prostaglandins E, Synthetic

1988
Prolongation of guinea pig-to-rat xenograft survival with BN 52063, a specific antagonist of platelet-activating factor.
    The Italian journal of surgical sciences, 1989, Volume: 19, Issue:4

    Topics: Animals; Epoprostenol; Graft Survival; Guinea Pigs; Heart Transplantation; Iloprost; Lactones; Liver; Liver Transplantation; Male; Myocardium; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Lew; Transplantation, Heterologous; Transplantation, Heterotopic

1989
Synergistic interaction between prostaglandins and PAF-acether in experimental animals and man.
    Prostaglandins, 1984, Volume: 27, Issue:3

    Topics: Animals; Cardiovascular Agents; Dinoprostone; Drug Synergism; Epoprostenol; Guinea Pigs; Humans; Iloprost; Platelet Activating Factor; Prostaglandins E; Serum Albumin; Skin

1984
S35b, a new phenylsulfonylfuroxan compound, inhibits thrombin-induced synthesis of platelet-activating factor and prostacyclin in human endothelial cells.
    Agents and actions, 1993, Volume: 40, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Iloprost; Oxadiazoles; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thrombin; Umbilical Veins

1993
E-type prostaglandins enhance local oedema formation and neutrophil accumulation but suppress eosinophil accumulation in guinea-pig skin.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Alprostadil; Animals; Dinoprostone; Edema; Eosinophils; Guinea Pigs; Iloprost; In Vitro Techniques; Indium Radioisotopes; Isoproterenol; Male; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Prostaglandins E; Skin; Zymosan

1993
Biogenesis of G-protein mediated calcium signaling in human megakaryocytes.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Calcium Signaling; Cattle; Cell Differentiation; Cells, Cultured; Fetal Blood; Flow Cytometry; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Iloprost; Megakaryocytes; Platelet Activating Factor; Protein Isoforms; Proto-Oncogene Proteins; Stem Cells; Thrombin; Thrombopoietin

2001