1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with histamine in 361 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 119 (32.96) | 18.7374 |
| 1990's | 181 (50.14) | 18.2507 |
| 2000's | 33 (9.14) | 29.6817 |
| 2010's | 21 (5.82) | 24.3611 |
| 2020's | 7 (1.94) | 2.80 |
| Authors | Studies |
|---|---|
| Lewis, SA; Raeburn, D; Underwood, SL | 1 |
| Armenaka, M; Rosenstreich, DL | 1 |
| Braquet, P; Kessels, GC; Nijkamp, FP; van Heuven-Nolsen, D | 2 |
| Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; e Silva, PM; Martins, MA; Pires, AL; Vargaftig, BB | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Tuomisto, L; Vapaatalo, H | 1 |
| Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M | 2 |
| Zhang, JN | 1 |
| Crea, AE; Lee, TH; Nakhosteen, JA | 1 |
| Beusenberg, FD; Bonta, IL; Brouwers, JW; Hekking, PR; Hoogsteden, HC; Schermers, HP; Van Amsterdam, JG | 1 |
| Juhlin, L; Pihl-Lundin, I | 1 |
| Cordeiro, RS; Diaz, BL; e Silva, PM; Lima, MC; Martins, MA; Pasquale, CP; Rihoux, JP; Vargaftig, BB | 1 |
| Bousquet, J; Chanez, P; Godard, P; Lacoste, JY; Michel, FB | 1 |
| Babycos, CR; Hood, JS; Ibrahim, IN; Kadowitz, PJ; McMahon, TJ; Nossaman, BD; Ragheb, MS | 1 |
| Barrett, KE | 1 |
| Lefort, J; Perrisoud, D; Pretolani, M; Vargaftig, BB; Venco, C | 1 |
| Calderón, E; Lockey, RF | 1 |
| Kubo, N; Kumazawa, T; Minami, T; Tomoda, K | 1 |
| Donigi-Gale, D; Herd, CM; Page, CP; Shoupe, TS | 1 |
| Abela, AP; Daniel, EE; Janssen, LJ; O'Byrne, PM | 1 |
| MacDermott, RP; Raedler, A; Schreiber, S; Stenson, WF | 1 |
| Hirafuji, M; Shinoda, H | 1 |
| Braquet, P; Koltai, M; Sipka, S; Szegedi, G | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 2 |
| Iwama, T; Koda, A; Nagai, H; Suda, H | 1 |
| Cardillo, R; DiMuzio, J; Post, TJ; Raible, DG; Schulman, ES | 1 |
| Befus, AD; Bissonnette, EY; Donigi-Gale, D; Hogaboam, CM; Shoupe, TS; Wallace, JL | 1 |
| Cunningham, FM; Foster, AP; Lees, P | 1 |
| Barnes, PJ; Chung, KF | 1 |
| Imanishi, N; Morooka, S; Uchida, M | 1 |
| Kobayashi, K; Takabatake, T; Ushiogi, Y | 1 |
| Durán, WN; Egan, RW; Tomeo, AC | 1 |
| Anglin, CP; Clapp, NK; Fretland, DJ; Gaginella, TS; Hansard, RM; Henke, MA; Walsh, RE; Widomski, DL | 1 |
| Baber, NS; Gill, D; James, I; Jordan, S; Sciberras, DG | 1 |
| Holgate, ST; Lai, CK; Lau, CK; Ollier, S | 1 |
| Cordeiro, RS; Lima, MC; Martins, MA; Perez, SA; Silva, PM; Vargaftig, BB | 1 |
| Colditz, IG | 1 |
| Teng, CM; Wang, JP | 1 |
| Chapman, ID; Hoshiko, K; Morley, J | 1 |
| Cordeiro, RS; Watson, ML; Weg, VB; Williams, TJ | 1 |
| Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M | 1 |
| Church, MK; Thomas, G | 1 |
| Flower, RJ; Peers, SH | 1 |
| Lorant, DE; McEver, RP; McIntyre, TM; Patel, KD; Prescott, SM; Zimmerman, GA | 1 |
| Bousquet, J; Braquet, P; Chanez, P; Damon, M; Godard, P; Mencia Huerta, JM; Michel, FB; Rabier, M | 1 |
| Drazen, JM; Martins, MA; Shore, SA | 1 |
| Becker, WM; Schade, U; Schaubschläger, WW; Schlaak, M; Zabel, P | 1 |
| Chapman, ID; Mazzoni, L; Morley, J | 1 |
| Braquet, P; Carré, C; Lellouch-Tubiana, A; Mencia-Huerta, JM; Page, CP; Pfister, A; Pignol, B; Touvay, C; Vilain, B | 1 |
| Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
| Barnes, PJ; Chung, KF; Lötvall, JO; Morikawa, A; Tokuyama, K | 1 |
| Hill, M; Irvin, CG; Nieminen, MM | 1 |
| Coyle, AJ; Manzini, S; McKenniff, MG; Page, CP; Perretti, F; Seeds, EA; Spina, D; Tramontana, M | 1 |
| Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Yamaguchi, T | 1 |
| Agrawal, DK; Bewtra, AK; Hopp, RJ; Townley, RG | 1 |
| Chan, CC; Chee, P; Ford-Hutchinson, A; McKee, K; Tagari, P | 1 |
| Buehn, MJ; Dabney, JM; Dobbins, DE | 1 |
| Iikura, Y; Kay, AB; Moqbel, R; Nagakura, T; Walsh, GM | 1 |
| Juhlin, L; Rihoux, JP | 1 |
| Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
| Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Tsurufuji, S; Watanabe, M; Yagi, M | 1 |
| Barnes, PJ; Chung, KF; Griffith, S; Hayes, JP; Ridge, SM | 1 |
| Iwamura, S; Misawa, M | 1 |
| Northover, AM | 2 |
| Hasunuma, K; McMurtry, IF; O'Brien, RF; Rodman, DM | 1 |
| Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
| Howell, RE | 1 |
| Inagaki, N; Koda, A; Miura, T; Nagai, H; Ohira, K; Xu, QA | 1 |
| Kaye, MG; Smith, LJ | 1 |
| Benveniste, J; Burtin, C; Noirot, C; Paupe, J; Scheinmann, P | 1 |
| Kristersson, A; Mazzoni, L; Morley, J; Sanjar, S; Schaeublin, E | 1 |
| Coyle, AJ; Page, CP; Spina, D | 1 |
| Rihoux, JP | 1 |
| Battistini, B; Braquet, P; Filep, JG; Sirois, P | 1 |
| Aoki, S; Kurosawa, M; Tsukagoshi, H | 1 |
| Armour, CL; Black, JL; Johnson, PR | 1 |
| Ikeda, S; Kawasaki, A; Motoishi, M; Nambu, F; Okegawa, T; Omawari, N | 1 |
| Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE | 1 |
| Handley, DA; Havill, AM; Van Valen, RG | 1 |
| Hayashi, M; Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
| Kim, ED; Roth, SI; Stock, EL; Thamman, R; Walsh, MK | 1 |
| Miyamoto, T; Nogami, M; Suko, M | 1 |
| Arimura, A; Harada, M; Nagata, M; Nakamura, K; Takeuchi, M; Watanabe, A | 1 |
| Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB | 1 |
| Dunn, AM; Halonen, M; McManus, LM; Palmer, JD | 1 |
| Fjellner, B; Hägermark, O | 1 |
| Brain, SD; Williams, TJ | 1 |
| Befus, AD; Bienenstock, J; Lee, TD; Swieter, M | 1 |
| Drazen, JM; Galli, SJ; Gerard, NP; Martin, TR | 1 |
| Holzer, P; Lippe, IT | 1 |
| Bregestovski, PD; Ryan, US | 1 |
| Fujii, T; Morimoto, H; Senoh, H | 1 |
| Lefort, J; Pretolani, M; Vargaftig, BB | 2 |
| Bekemeier, H; Sänze, JU | 1 |
| Ewenstein, BM; Pober, JS; Schafer, AI; Zavoico, GB | 1 |
| Hampel, G; Jaffe, EA; Watanabe, K; Weksler, BB | 1 |
| Gudgeon, JR; Martin, W | 1 |
| Braquet, P; Mencia-Huerta, JM; Pfister, A; Pignol, B; Touvay, C | 1 |
| Iikura, Y; Nagakura, T; Walsh, GM | 1 |
| Danilov, SM; Grigorian, GY; Mirzapoyazova, TY; Resink, TJ; Tkachuk, VA | 1 |
| Arnoux, B; Benveniste, J; Miadonna, A; Sala, A; Tedeschi, A; Zanussi, C | 1 |
| Jin, LS; Page, CP; Schachter, M; Seeds, E | 1 |
| Hawley, SB; Nieves, AL; Spada, CS; Williams, LS; Woodward, DF | 1 |
| Gallasch, M; Ignat'eva, VB; Kobrinskiĭ, EM; Kukushkin, NI; Vornovitskiĭ, EG | 1 |
| Atkinson, L; Coyle, AJ; Metzger, WJ; Page, CP; Sjoerdsma, K; Touvay, C | 1 |
| Fortes, ZB; Garcia-Leme, J; Scivoletto, R | 1 |
| Bousquet, J; Chanez, P; Clauzel, AM; Godard, P; Michel, FB; Pujol, JL | 1 |
| Braquet, P; Mencia-Huerta, JM; Pfister, A; Touvay, C | 1 |
| Blake, JS; Leff, AR; Mack, MM; Moss, J; Munoz, NM; Murphy, TM | 1 |
| Aursudkij, B; Barnes, PJ; Chung, KF; Evans, TW; Rogers, DF | 1 |
| Calixto, JB; Medeiros, YS; Torres, RC | 1 |
| Antoniw, JW; Izumi, T; Piper, PJ; Stanton, AW | 1 |
| Dixon, EJ; Page, CP; Robertson, DN; Wilsoncroft, P | 1 |
| Hamilton, JT; Paterson, NA; Yaghi, A | 1 |
| Bousquet, J; Braquet, P; Chanez, P; Damon, M; Godard, P; Mencia-Huerta, JM; Michel, FB; Rabier, M | 1 |
| Inoue, T; Kannan, MS | 1 |
| Becker, AB; Brandes, LJ; Gerrard, JM; McNicol, A; Saxena, SP | 1 |
| Anderson, GP; Fennessy, MR; Stewart, AG | 1 |
| Braquet, P; Carré, C; Mencia-Huerta, JM; Touvay, C; Vilain, B | 1 |
| Brain, SD; Hellewell, PG; Jose, PJ; Nourshargh, S; Rampart, M; Williams, TJ | 1 |
| Anderson, GP; Fennessy, MR | 2 |
| Barnes, PJ; Coyle, AJ; Grandordy, B; Page, CP; Rhoden, KJ; Robertson, DN | 1 |
| Danilov, SM; Shirinsky, VP; Sobolevsky, AV; Tararak, EM; Tkachuk, VA | 1 |
| McIntyre, TM; Prescott, SM; Satoh, K; Zimmerman, GA | 1 |
| Hackenthal, E; Taugner, R | 1 |
| Ghezzi, E | 1 |
| Benveniste, J; Burtin, C; De Vos, C; Dubertret, L; Michel, L; Rihoux, JP | 1 |
| Aizawa, H; Ejima, T; Miyazaki, N; Shigematsu, N; Tomooka, M | 1 |
| Gollash, M; Ignat'eva, VB; Kulikov, VI; Lipatkina, LIu; Vornovitskiĭ, EG | 1 |
| Beattie, TR; Biftu, T; Hwang, SB; Lam, MH; Shen, TY | 1 |
| Wasserman, SI | 3 |
| Damas, J | 1 |
| Deacon, RW; Farley, C; Handley, DA; Saunders, RN | 1 |
| Auer, H; Egger, D; Fechter, M; Popper, H | 1 |
| Darius, H; Lefer, AM; Smith, JB | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Braquet, P; Clostre, F; Etienne, A; Touvay, C; Vilain, B | 1 |
| Bussolino, F; Camussi, G; Gremo, F; Pescarmona, GP; Tetta, C | 1 |
| Agrawal, DK; Townley, RG | 1 |
| Barnes, PJ; Grandordy, BM; Page, CP; Rhoden, KJ; Robertson, DN | 1 |
| Barnett, CJ; O'Donnell, SR | 1 |
| Barnes, PJ | 2 |
| Lewis, RA | 1 |
| Burka, JF | 1 |
| Botting, R; Vane, J | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Mariano, F; Meda, E; Montrucchio, G; Tetta, C | 1 |
| Smith, TF | 1 |
| Anderson, GP; Fennessy, MR; White, HL | 1 |
| Anderson, G; Fennessy, M | 1 |
| Miadonna, A; Tedeschi, A | 1 |
| Mezawa, A | 1 |
| Misawa, M; Takata, T | 1 |
| Avdonin, PV; Danilov, SM; Popov, EG; Posin, EY; Ryan, US; Tkachuk, VA | 1 |
| Advenier, C; Fichelle, J; Freslon, JL; Jouquey, S; Miller, P; Naline, E; Plassard, G; Thompson, MA | 1 |
| Berti, F; Magni, F; Rossoni, G | 1 |
| Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
| Ferguson, MK; Michelassi, F; Shahinian, HK | 1 |
| Lee, CO; Levi, R; Robertson, DA; Wang, DY | 1 |
| Berti, F; Bongrani, S; Magni, F; Pasargiklian, R; Rossoni, G; Schiantarelli, P | 1 |
| Barnes, PJ; Chung, KF; Page, CP; Roberts, NM | 1 |
| Kohno, SW; Ohata, K; Taira, M; Yamamura, H | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Angle, MJ; McManus, LM; Pinckard, RN | 1 |
| Benveniste, J; Brink, C; Brunelleschi, S; Haye-Legrand, I; Labat, C; Norel, X | 1 |
| Adkinson, NF; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Pinckard, RN; Schleimer, RP | 1 |
| Moudgil, GC | 1 |
| Braquet, P; Jancar, S; Sirois, P; Thériault, P | 1 |
| Christman, BW; Lefferts, PL; Snapper, JR | 1 |
| Lefort, J; Malanchère, E; Pretolani, M; Vargaftig, BB | 1 |
| Bruniquel, F; Couzinier, JP; Delhon, A; Puech, L; Tarayre, JP; Tisne-Versailles, J | 1 |
| Cutcher, A; Dunn, AM; Halonen, M; Holmes, T; Palmer, JD; Smith, PF | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W | 1 |
| Hwang, SB; Lam, MH; Li, CL; Shen, TY | 1 |
| Moore, TL; Weiss, TD | 1 |
| Gerdin, B; Lundberg, C; Smedegøard, G | 1 |
| Nunn, B; Ross, JW; Spicer, BA | 1 |
| Detsouli, A; Lefort, J; Vargaftig, BB | 1 |
| Handley, DA; Lee, ML; Saunders, RN | 1 |
| Metcalfe, DD | 1 |
| O'Flaherty, JT | 1 |
| Bach, MK | 1 |
| Adams, GK; Adkinson, NF; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Schleimer, RP; Schulman, ES | 1 |
| Vargaftig, BB | 2 |
| Kalter, ES | 1 |
| Cervoni, P; Lai, FM; Shepherd, CA; Wissner, A | 1 |
| Kumahara, Y; Masugi, F; Ogihara, T; Otsuka, A; Saeki, S | 1 |
| Henson, PM; Larsen, GL | 1 |
| Barth, T; Bekemeier, H; Hänsel, F; Hirschelmann, R; Sänze, JU | 1 |
| Hanahan, DJ; Humphrey, DM; McManus, LM; Pinckard, RN | 1 |
| Burrell, R; Gee, JB; Morgan, WK; Vesterlund, J; Willoughby, WF | 1 |
| Antro, C; Bussolino, F; Camussi, G; Emanuelli, G; Montrucchio, G; Tetta, C | 1 |
| Soter, NA; Wintroub, BU | 1 |
| Hanahan, DJ; Humphrey, DM; McManus, LM; Pinckard, RN; Satouchi, K | 1 |
| Barton, M; Lefort, J; Prancan, A; Vargaftig, BB | 1 |
| Alonso, F; Barat, A; Egido, J; Sánchez-Crespo, M | 1 |
| Findlay, SR; Hanahan, DJ; Lichtenstein, LM; Pinckard, RN | 1 |
| Abelli, L; Evangelista, S; Manzini, S; Page, CP; Perretti, F; Seeds, EA | 1 |
| Inagaki, N; Iwama, T; Kitagaki, K; Koda, A; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Kanwar, S; Kubes, P | 1 |
| Kamei, C; Nakamura, S; Tasaka, K | 1 |
| Autore, G; Capasso, F; Di Carlo, G; Di Urno, MV; Izzo, AA; Mascolo, N | 1 |
| Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Hughes, SC; Whelan, CJ; Wren, GP | 1 |
| Aida, Y; Kasama, T; Takeuchi, N; Tobinaga, S | 1 |
| Bandeira-Melo, C; Cordeiro, RS; e Silva, PM; Martins, MA | 1 |
| Adler, KB; Choe, NH; Fischer, BM; Li, H; Wright, DT | 1 |
| Bado, A; Braquet, P; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I; Tarrade, T | 1 |
| Juhlin, L | 1 |
| Akagi, M; Akagi, R; Fukuishi, N; Kanoh, R; Tachibana, M | 1 |
| Binder, BR; Gajdzik, L; Graf, J; Maier, M; Tschugguel, W; Zhegu, Z | 1 |
| Levi-Schaffer, F; Slavin, S; Vourka-Karussis, U | 1 |
| Bendele, AM; Cockerham, SL; Silbaugh, SA; Stengel, PW | 1 |
| Manzini, S; Perretti, F | 1 |
| Herd, CM; Page, CP; Sasaki, M | 1 |
| Fan, TP; Gresham, GA; Guard, S; Hu, DE; Watling, KJ | 1 |
| Parnell, DW; Spellman, JM; Stephens, DJ; Yanni, JM | 1 |
| Aikawa, T; Han, L; Koyanagi, M; Matsumoto, I; Shimada, T; Yang, H | 1 |
| Ballati, L; Evangelista, S; Maggi, CA; Manzini, S; Perretti, F | 1 |
| Gaboury, JP; Johnston, B; Kubes, P; Niu, XF | 1 |
| Nieves, AL; Spada, CS; Tuckett, RP; Williams, LS; Woodward, DF | 1 |
| Howell, RE; Kovalsky, MP; Laemont, KD | 1 |
| Battram, CH; Jordan, R; Lewis, SA; Raeburn, D; Sharma, S; Souness, JE; Tomkinson, A; Underwood, SL; Webber, SE; Woodman, VR | 1 |
| Johnson, M; Vardey, CJ; Whelan, CJ | 1 |
| Barnes, PJ; Chung, KF; Sakamoto, T | 1 |
| Bou, J; Cortijo, J; Morcillo, EJ; Ortiz, JL; Vallés, JM | 1 |
| Almansa, C; Balsa, D; Bartrolí, J; Carceller, E; Forn, J; García-Rafanell, J; Giral, M; Merlos, M | 1 |
| Colditz, IG; Eisemann, CH | 1 |
| Dahlén, SE; Jonsson, EW | 1 |
| Iwama, T; Nagai, H; Sakurai, T; Yamaguchi, S | 1 |
| Donigi-Gale, D; Herd, CM; Kilfeather, SA; Okiji, SA; Page, CP; Shoupe, TS | 1 |
| de Brum Fernandes, AJ; de Lima, WT; Johnson, RJ; Plante, GE; Sirois, MG; Sirois, P | 1 |
| De Clerck, F; Folkerts, G; Nijkamp, FP; Reijnart, I; Span, P | 1 |
| Averill, FJ; Baroody, FM; Chilton, FH; Hubbard, WC; Liu, MC; Naclerio, RM; Shin, MH | 1 |
| Andrews, MJ; Cunningham, FM; Foster, AP; Lees, P | 1 |
| Henderson, WR; Koenig, JQ; Luchtel, DL; McBride, DE; Williams, PV | 1 |
| Cabré, F; Carganico, G; Gutiérrez, M; Mauleón, D; Suesa, N; Tost, D; Ucedo, P | 1 |
| Austin, CE; Foreman, JC | 1 |
| De Brum-Fernandes, AJ; Fraga, CA; Jancar, S; Rocha, FA; Timo-Iaria, C | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Bury, T; Corhay, JL; Louis, R; Radermecker, M | 1 |
| Erl, W; Kruse, HJ; Sellmayer, A; Weber, C; Weber, PC | 1 |
| Kurosawa, M; Tsukagoshi, H | 1 |
| Bozza, PT; Cordeiro, RS; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Sunkel, CE | 1 |
| Lu, Z; Wolf, MB | 1 |
| Kubo, N; Kumazawa, T; Minami, T; Tomoda, K; Yamashita, T | 1 |
| Kitagaki, K; Koda, A; Nagai, H; Tsuruoka, N; Yamaguchi, S | 1 |
| Seow, WK; Thong, YH; Wong, CW | 1 |
| Björck, T; Dahlén, SE | 1 |
| Halonen, M; Lohman, IC | 1 |
| Durán, WN; Fallek, SR; Hobson, RW; Noel, AA | 1 |
| Flower, RJ; Harris, JG; Perretti, M; Tsurufuji, S; Watanabe, K; Wolitzky, BA | 1 |
| de Abreu Castro, MS; Dias, MF; Farinelli, P; Ferreira-Alves, DL; Francischi, JN; Kiyomi Funayama Tatsuo, MA; Pacheco, CM; Rocha, OA; Sirois, P | 1 |
| Aïssa, J; Benveniste, J; Boucherie, S; Brouilhet, H; Harran, H; Rabeau, M | 1 |
| Buravkova, L; Erne, P; Köhler, E; Mirzapoyazova, T; Resink, T; Tkachuk, V | 1 |
| Hall, L; Turnberg, LA; Wardle, TD | 1 |
| Bado, A; Benveniste, J; Denizot, Y; Laboisse, C; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I | 1 |
| Archer, CB; Brooks, J; Burton, JL; Sansom, JE | 1 |
| Cortijo, J; Martí-Cabrera, M; Morcillo, EJ; Ortiz, JL; Vallés, JM | 1 |
| Hedqvist, P; Lindbom, L; Raud, J; Thorlacius, H; Xie, X | 1 |
| Donigi-Gale, D; Kilfeather, S; Okiji, S; Page, CP; Schoupe, TS; Seeds, EA | 1 |
| Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A | 1 |
| Akiyama, K; Maeda, Y; Mita, H; Saito, H; Shimizu, H | 1 |
| Knol, EF; Lie, WJ; Mul, FP; Roos, D; Verhoeven, AJ | 1 |
| Anger, T; Beger, HG; Gansauge, F; Gansauge, S; Nilsson, U; Poch, B; Schoenberg, MH | 1 |
| Igarashi, Y; Kurosawa, M; Miyachi, Y; Tsukagoshi, H | 1 |
| Biggs, S; Gasper, S; Mckernan, PA; Piggott, J; Rassing, B; Van Ness, J; Varming, AM; West, RR | 1 |
| Ito, S; Komiyama, Y; Miwa, M; Sugatani, J | 1 |
| Chen, IS; Ishii, H; Ishikawa, T; Ko, FN; Kuo, HP; Lin, CH; Teng, CM | 1 |
| Akuta, K; Ichimura, M; Kase, H; Kawakita, T; Kawasaki, H; Kitamura, S; Manabe, H; Nukui, E; Ohmori, K; Sato, S; Sejimo, H; Suzuki, F | 1 |
| Oh-ishi, S | 1 |
| de Medicis, R; Flower, RJ; Getting, SJ; Lussier, A; Martins, MA; Parente, L; Perretti, M; Woliztky, BA | 1 |
| Howarth, PH | 1 |
| Koyama, S; Miyahara, T; Shibamoto, T; Wang, HG | 1 |
| Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S | 1 |
| Egashira, K; Fukumoto, Y; Kadokami, T; Katsumata, N; Kozai, T; Kuwata, K; Shimokawa, H; Takeshita, A; Yamawaki, T | 1 |
| Akagi, M; Fukuishi, N; Kanoh, R; Nishioka, E; Tachibana, M | 1 |
| Chung, KF | 1 |
| Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG | 1 |
| Chai, OH; Choi, IH; Ha, TY; Han, EH; Im, SY; Lee, HK; Lee, MS; Park, JS; Shin, YM | 1 |
| Ito, K; Nakagawa, T; Tadokoro, K; Takafuji, S | 1 |
| Griffin, BW; Howe, WE; Offord, EA; Pfeifer, AM; Sharif, NA; Wiernas, TK | 1 |
| Hirano, Y; Inagaki, N; Kawada, K; Nagai, H; Nakamura, N; Takatsu, K; Tanaka, H; Ueda, Y | 1 |
| Beadle, RE; Holmes, EP; Seahorn, TL; Venugopalan, CS | 1 |
| Guo, ZG; Zeng, S | 1 |
| Takami, M; Tsukada, W | 1 |
| Carvalho-Tavares, J; Fox-Robichaud, A; Kubes, P | 1 |
| Archer, CB; Bradfield, JW; Brooks, J; Jenks, PJ; Kavanagh, GM | 1 |
| Chambers, EL; Downing, SJ; Leese, HJ; Maguiness, SD; Watson, A | 1 |
| Boronkay, E; Gyürky, J; Herbert, JM; Kapui, Z; Mikus, EG; Pascal, M; Schaeffer, P | 1 |
| Fox-Robichaud, A; Kubes, P; Payne, D | 1 |
| Andrews, MJ; Bailey, SR; Cunningham, F; Elliott, J | 1 |
| Ohishi, S | 1 |
| Akiyama, H; Goda, Y; Okunuki, H; Sakushima, J; Sawada, JI; Teshima, R; Toyoda, M | 1 |
| Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
| Calabrese, R; del Basso, P; Fabi, F; Stati, T | 1 |
| Apostoliti, F; Breschi, MC; Martinotti, E; Nieri, P | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC | 1 |
| Mahgoub, AA | 1 |
| Glynos, K; Papapetropoulos, A; Pizurki, L; Roussos, C; Zhou, Z | 1 |
| Akamine, E; Carvalho, MH; Fortes, ZB; Nigro, D; Passaglia, RC; Toledo, DP | 1 |
| Bardhan, KD; Kalia, N | 1 |
| Awong, G; Cuvelier, SL; Iqbal, SM; Patel, KD; Tibbles, LA; Wierzbicki, T | 1 |
| Alfaro, V | 1 |
| Barbanoj, MJ; García-Gea, C; Izquierdo, I; Jané, F; Morte, A; Pérez, I | 1 |
| Takeda, K | 1 |
| Leung, JW; Mann, NS | 1 |
| Aarons, L; Brearley, C; Evans, L | 1 |
| Abo, M; Fujimura, M; Ishiura, Y; Myou, S; Nobata, K; Nonomura, A; Oribe, Y | 1 |
| Choi, IW; Im, SY; Kim, JH; Kim, YS; Ko, HM; Lee, HK; Lee, JH; Lee, YC; Park, YM; You, HJ | 1 |
| Basilico, F; Bombardelli, E; De Palma, A; Mauri, P; Morazzoni, P; Pozzi, F; Riva, A; Rossoni, G | 1 |
| Borgeat, P; Bourgoin, SG; Flamand, N; Lapointe, G; Lefebvre, J; Lemieux, L; Picard, S | 1 |
| Jauchem, JR | 1 |
| Alton, EW; Geddes, DM; Griesenbach, U; Holder, E; Huang, L; Jeffery, PK; Li, S; Rogers, DF | 1 |
| Choi, IH; Choi, IW; Chung, WC; Kang, NI; Kim, YS; Lee, HK; Song, CH; Woo, HY | 1 |
| Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF | 1 |
| Adachi, Y; Kurihara, K; Nagi-Miura, N; Ohno, N; Shingo, Y; Suzuki, K | 1 |
| Levy, JH | 1 |
| Kato, Y; Kremenik, MJ; Matsumoto, T; Shiva, D; Yano, H | 1 |
| Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H; Zhang, W | 1 |
| Finkelman, FD; Herbert, DR; Hogan, S; Karasuyama, H; Khodoun, M; Köhl, J; Orekov, T; Strait, R | 1 |
| Boon, L; Galli, SJ; Mantegazza, R; Musio, S; Ohtsu, H; Pedotti, P; Pedotti, R; Steinman, L | 1 |
| Frey, M; Herndon, DH; Jeschke, MG; Kamolz, LP; Keck, M | 1 |
| Atsumi, I; Fujii, A; Iemura, M; Kida, T; Sakai, O; Sakaki, H; Wada, T | 1 |
| Ferrer, M; Gamboa, PM; García-Figueroa, BE; Sanz, ML | 1 |
| Church, MK | 1 |
| Liss, G; Perelman, B; Vadas, P | 1 |
| Hirayama, F | 1 |
| Abajian, M; Church, MK; Farré-Albadalejo, M; Giménez-Arnau, A; Krause, K; Martinez-Escala, E; Maurer, M | 1 |
| Wang, HL; Wang, LC; Wei, JW | 1 |
| Merk, HF; Vanstreels, L | 1 |
| He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H | 1 |
| Bongrand, P; Vitte, J | 1 |
| Vadas, P | 1 |
| Alevizos, M; Kalogeromitros, D; Karagkouni, A; Makris, M; Sismanopoulos, N; Theoharides, TC; Vasiadi, M | 1 |
| Montagni, M; Parente, R; Ridolo, E; Triggiani, M | 1 |
| Kuda, Y; Kurata, Y; Shibamoto, T; Tanida, M; Wang, M | 1 |
| Ebina, K; Oe, K; Sato, A; Yamanaka, H; Yokoyama, I | 1 |
| Kuda, Y; Kurata, Y; Shibamoto, T; Song, J; Tanida, M; Wang, M; Zhang, T | 1 |
| Kuda, Y; Kurata, Y; Mukai, K; Shibamoto, T; Song, J; Tanida, M; Wang, M; Zhang, T | 1 |
| Goto, S; Itoh, H; Nagai, M; Ohmori, K; Osada, H; Sasaki, K; Shimizu, S; Shimoda, M; Shirai, J; Watanabe, M | 1 |
| Hasegawa, A; Ogawa, M; Ohmori, K; Ohno, H; Osada, H; Sasaki, K; Shimoda, M; Shirai, J; Watanabe, M; Yanuma, N | 1 |
| Bodzenta-Łukaszyk, A; Klimek, M; Lis, A; Moniuszko, M; Tomasiak-Łozowska, MM | 1 |
| Cardona, V; Guilarte, M; Sala-Cunill, A | 1 |
| Ballesteros-Martinez, C; Beitia, JM; Blanco-Colio, LM; Cuesta-Herranz, J; Díaz-Perales, A; Esteban, V; Garrido-Arandia, M; Gutiérrez-Muñoz, C; Jensen, BM; Laguna, JJ; Mendez-Barbero, N; Nuñez-Borque, E; Poulsen, LK; Tome-Amat, J; Yuste-Montalvo, A | 1 |
| Galli, SJ | 1 |
| Bruhns, P; Chollet-Martin, S | 1 |
| Abdel Hafez, SMN; Abdel-Gaber, SA; Abdelmonaem, AA; Hafez, HM; Ibrahim, MA; Yehia Abdelzaher, W | 1 |
| Sharif, NA | 1 |
| Abas, F; Israf, DA; Khoo, LW; Kow, ASF; Lee, MT; Shaari, K; Tan, JW; Tham, CL | 1 |
| Kuda, Y; Kurata, Y; Ono, M; Shibamoto, T; Tanida, M | 1 |
49 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and histamine
| Article | Year |
|---|---|
The pathophysiology of chronic urticaria.
Topics: Chronic Disease; Histamine; Humans; Immunoglobulin E; Kinins; Leukotrienes; Mast Cells; Platelet Activating Factor; Prostaglandins; Urticaria | 1992 |
[Mediators and neuromediators in asthma].
Topics: Asthma; Atrial Natriuretic Factor; Cytokines; Histamine; Humans; Leukotrienes; Parasympathetic Nervous System; Platelet Activating Factor; Prostaglandins; Substance P; Sympathetic Nervous System; Sympathomimetics; Vasoactive Intestinal Peptide | 1992 |
A possible role for adhesion molecules in asthma.
Topics: Asthma; Basophils; Cell Adhesion Molecules; Cytokines; Eosinophils; Genes, Immunoglobulin; Histamine; Humans; Hydrogen Peroxide; Integrins; Leukotrienes; Mast Cells; Platelet Activating Factor | 1992 |
The role of the mucosal immune system in inflammatory bowel disease.
Topics: Antibody Formation; Bacterial Toxins; Complement Pathway, Alternative; Complement Pathway, Classical; Cytokines; Cytotoxicity, Immunologic; Free Radicals; Granulocytes; Histamine; Humans; Immunity, Cellular; Immunoglobulins; Inflammatory Bowel Diseases; Intestinal Mucosa; Leukotrienes; Lymphocyte Activation; Macrophages; Mast Cells; Oxygen; Platelet Activating Factor; Prostaglandins; T-Lymphocytes | 1992 |
Role of inflammatory mediators in asthma.
Topics: Asthma; Bronchi; Histamine; Humans; Lipoxygenase; Platelet Activating Factor; Prostaglandins | 1992 |
[Miscellaneous factors on mechanisms of blood pressure regulation].
Topics: Adenosine; Animals; Blood Pressure; Glucagon; Histamine; Humans; Hypertension; Lipids; Neuropeptide Y; Platelet Activating Factor; Thyroid Hormones | 1992 |
[Allergic reaction and vascular permeability].
Topics: Animals; Capillary Permeability; Catecholamines; Complement C3a; Complement C5a; Histamine; Humans; Hypersensitivity; Kinins; Leukotrienes; Neuropeptides; Platelet Activating Factor; Prostaglandins | 1990 |
Heterogeneity in mast cell populations.
Topics: Animals; Cell Differentiation; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Cromolyn Sodium; Cytoplasmic Granules; Exocytosis; Histamine; Histamine Release; Humans; Hypersensitivity; Intestinal Mucosa; Lung; Mast Cells; Organoids; Peptide Hydrolases; Peritoneal Cavity; Platelet Activating Factor; Proteoglycans; Skin; Species Specificity | 1985 |
Voltage-gated and receptor-mediated ionic currents in the membrane of endothelial cells.
Topics: Animals; Bradykinin; Cattle; Endothelium, Vascular; Histamine; Humans; Ion Channels; Membrane Potentials; Platelet Activating Factor; Thrombin | 1989 |
[Physiopathology of asthma].
Topics: Allergens; Animals; Arachidonic Acids; Asthma; Autonomic Nervous System; Basophils; Guinea Pigs; Histamine; Humans; Immunoglobulin E; Mast Cells; Platelet Activating Factor; Rats | 1989 |
Lipid mediators of anaphylaxis and increased airways reactivity.
Topics: Anaphylaxis; Arachidonic Acids; Asthma; Bronchitis; Histamine; Humans; Leukotriene B4; Lipid Metabolism; Platelet Activating Factor; SRS-A | 1987 |
Alteration in microvascular permeability induced by products released during inflammation.
Topics: Animals; Bradykinin; Capillary Permeability; Complement C5; Complement C5a; Histamine; Humans; Inflammation; Leukotriene B4; Lung; Neuropeptides; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Hormonal signals and intracellular messengers for renin secretion.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cyclic AMP; Cyclic GMP; Dopamine; Epinephrine; Histamine; Hormones; Nerve Tissue Proteins; Neuropeptide Y; Norepinephrine; Platelet Activating Factor; Prostaglandins; Renin; Vasopressins | 1986 |
Autacoids and some mediators in allergic and non allergic forms.
Topics: Animals; Arachidonic Acids; Autacoids; Histamine; Humans; Hypersensitivity; Inflammation; Lipoxygenase; Models, Biological; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1986 |
Inflammatory mechanisms and nocturnal asthma.
Topics: Adenosine; Asthma; Blood Platelets; Circadian Rhythm; Eosinophils; Epithelium; Histamine; Humans; Inflammation; Lymphocytes; Macrophages; Mast Cells; Neutrophils; Platelet Activating Factor; Prostaglandins; SRS-A | 1988 |
Mast cell-dependent immediate hypersensitivity responses.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Chemotaxis, Leukocyte; Enzyme Activation; Histamine; Humans; Hypersensitivity, Immediate; Mast Cells; Peptide Hydrolases; Phospholipids; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; SRS-A; Type C Phospholipases | 1986 |
The interaction of histamine with other bronchoconstrictor mediators.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Asthma; Bronchi; Histamine; Humans; Muscle Contraction; Platelet Activating Factor | 1987 |
Inflammation and the mechanism of action of anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Bradykinin; Colchicine; Cyclooxygenase Inhibitors; Gold; Histamine; Humans; Inflammation; Interleukin-1; Lipoxygenase Inhibitors; Platelet Activating Factor; Salicylates | 1987 |
Allergy and pseudoallergy: an overview of basic mechanisms.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Basophils; Chemotaxis; Drug Hypersensitivity; Histamine; Humans; Hypersensitivity; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Mast Cells; Platelet Activating Factor | 1987 |
[Mediators of immunologic inflammation of the respiratory tract].
Topics: Allergens; Arachidonic Acid; Arachidonic Acids; Asthma; Blood Platelets; Bronchial Provocation Tests; Histamine; Humans; Inflammation; Kinins; Leukocytes; Leukotrienes; Macrophages; Mast Cells; Nasal Provocation Tests; Platelet Activating Factor; Prostaglandins; Respiratory Hypersensitivity; Rhinitis, Allergic, Seasonal | 1988 |
Anaesthesia and allergic drug reactions.
Topics: Anaphylaxis; Anesthesia; Anesthetics; Drug Hypersensitivity; Histamine; Humans; Platelet Activating Factor; Prostaglandins; Skin Tests | 1986 |
Mast cell mediators in the blood of patients with asthma.
Topics: Adenosine; Antigens; Asthma; Bronchial Spasm; Chemotactic Factors; Histamine; Humans; Mast Cells; Platelet Activating Factor; Urticaria | 1985 |
Mediators of inflammation.
Topics: Arachidonic Acid; Arachidonic Acids; Chemotactic Factors, Eosinophil; Complement Membrane Attack Complex; Complement Pathway, Alternative; Complement Pathway, Classical; Complement System Proteins; Factor XI; Factor XII; Histamine; Humans; Inflammation; Kininogens; Mast Cells; Platelet Activating Factor; Prekallikrein | 1985 |
Mast cell mediators with emphasis on intestinal mast cells.
Topics: Aging; Animals; Arachidonic Acid; Arachidonic Acids; Arylsulfatases; Chemotactic Factors; Cytoplasmic Granules; Food Hypersensitivity; Gastric Mucosa; Glycoside Hydrolases; Heparin; Histamine; Humans; Hypersensitivity, Immediate; Intestinal Mucosa; Intestines; Lysosomes; Mast Cells; Oligopeptides; Peptide Hydrolases; Peroxidases; Platelet Activating Factor; Proteoglycans; Receptors, Histamine; Serotonin; Skin; Substrate Specificity; Superoxide Dismutase; Superoxides; Tissue Distribution | 1984 |
Lipid mediators of inflammation and allergy.
Topics: Anaphylatoxins; Anaphylaxis; Animals; Antibodies; Arachidonic Acids; Autacoids; Blood Platelets; Bradykinin; Complement System Proteins; Dogs; Haplorhini; Histamine; Humans; Hypersensitivity; Inflammation; Lipids; Neutrophils; Platelet Activating Factor; Rabbits; Serotonin | 1982 |
Mediators of anaphylaxis and inflammation.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Arachidonic Acids; Autacoids; Chemical Phenomena; Chemistry; Chemotactic Factors; Chemotactic Factors, Eosinophil; Histamine; Humans; Hydrolases; Inflammation; Leukocytes; Leukotriene B4; Mast Cells; Platelet Activating Factor; Prostaglandins; Serotonin; SRS-A; Structure-Activity Relationship; Thromboxanes; Vasoactive Intestinal Peptide | 1982 |
Studies with purified human basophils and mast cells.
Topics: Arachidonic Acid; Arachidonic Acids; Basophils; Cell Separation; Histamine; Histamine Release; Humans; Leukotrienes; Mast Cells; Peptide Hydrolases; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; Receptors, IgE; Receptors, Immunologic | 1983 |
Inflammatory mediators and acute infections.
Topics: Arachidonic Acid; Arachidonic Acids; Complement Activation; Factor XII; Histamine; Humans; Infections; Inflammation; Neutrophils; Platelet Activating Factor; Receptors, Histamine H1; Receptors, Histamine H2; Shock, Septic | 1984 |
Mediators of inflammation.
Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement C5; Histamine; Humans; Hyperemia; Inflammation; Kinins; Peptides; Platelet Activating Factor; Prostaglandins; Vasodilation | 1983 |
The human lung mast cell.
Topics: Arachidonic Acid; Arachidonic Acids; Biotransformation; Bradykinin; Chemotaxis; Enzymes; Histamine; Humans; Lung; Lung Diseases; Mast Cells; Muscle, Smooth; Muscle, Smooth, Vascular; Oxidation-Reduction; Platelet Activating Factor; Serotonin | 1984 |
Biology of the mast cell and its role in cutaneous inflammation.
Topics: Animals; Bone Marrow Cells; Chemotactic Factors; Chemotactic Factors, Eosinophil; Cytoplasmic Granules; Dermatitis; Histamine; Humans; Interleukin-8; Lysophosphatidylcholines; Mast Cells; Mitosis; Muscle Contraction; Muscle, Smooth; Nucleotides, Cyclic; Platelet Activating Factor; Proteoglycans; Rats; SRS-A | 1981 |
A comparison of the pharmacodynamics of H1-receptor antagonists as assessed by the induced wheal-and-flare model.
Topics: Allergens; Bronchoconstriction; Clinical Trials as Topic; Dermatitis, Allergic Contact; Histamine; Histamine H1 Antagonists; Humans; Platelet Activating Factor; Skin Tests | 1995 |
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C5a; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine Release; Humans; Hypersensitivity; Interleukin-3; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nasal Lavage Fluid; Phorbol Esters; Platelet Activating Factor; Prostaglandin D2; Receptors, IgE; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Thapsigargin; Tryptases | 1996 |
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
Mediators of nasal blockage in allergic rhinitis.
Topics: Histamine; Humans; Kinins; Leukotrienes; Nasal Obstruction; Platelet Activating Factor; Prostaglandin D2; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Substance P | 1997 |
[Evaluation of time course and inter-relationship of inflammatory mediators in experimental inflammatory reaction].
Topics: Animals; Complement System Proteins; Cytokines; Histamine; Humans; Inflammation; Inflammation Mediators; Kallikrein-Kinin System; Platelet Activating Factor; Rats; Time Factors | 2000 |
Of blood and guts: association between Helicobacter pylori and the gastric microcirculation.
Topics: Blood Platelets; Cell Adhesion Molecules; Gastritis; Helicobacter Infections; Helicobacter pylori; Histamine; Humans; Mast Cells; Microcirculation; Platelet Activating Factor; Regional Blood Flow; Stomach | 2003 |
Role of histamine and platelet-activating factor in allergic rhinitis.
Topics: Animals; Histamine; Humans; Models, Biological; Molecular Structure; Platelet Activating Factor; Rhinitis, Allergic, Perennial | 2004 |
[Role of increase in permeability and circulatory failure in the development of organ dysfunction in severe acute pancreatitis].
Topics: Acute Disease; Animals; Bradykinin; Capillary Permeability; Formycins; Histamine; Humans; Interleukin-1; Microcirculation; Neutrophil Infiltration; Pancreatitis; Platelet Activating Factor; Ribonucleotides; Severity of Illness Index; Shock; Thrombin; Thrombophilia; Tumor Necrosis Factor-alpha | 2004 |
The role of autacoids and the autonomic nervous system in cardiovascular responses to radio-frequency energy heating.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autacoids; Autonomic Nervous System; Blood Pressure; Body Temperature; Heart Rate; Heat Stress Disorders; Histamine; Humans; Nitric Oxide; Platelet Activating Factor; Radio Waves; Receptors, Adrenergic; Shock | 2006 |
Pathophysiology of burns.
Topics: Angiotensin II; Animals; Burns; Catecholamines; Edema; Hemodynamics; Histamine; Humans; Hypovolemia; Inflammation Mediators; Platelet Activating Factor; Prostaglandins; Serotonin; Skin; Soft Tissue Injuries; Thromboxanes; Vascular Resistance; Vasopressins | 2009 |
In vitro diagnosis of anaphylaxis.
Topics: Anaphylaxis; Animals; Basophil Degranulation Test; Histamine; Humans; Immunoglobulin E; Leukotrienes; Mast Cells; Platelet Activating Factor; Tryptases | 2010 |
Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment.
Topics: Allergens; Anaphylaxis; Antibodies; Basophils; Blood Proteins; Histamine; Humans; Immunity, Cellular; Immunization, Passive; Immunoglobulin A; Immunoglobulin E; Immunologic Tests; Mast Cells; Plasma; Platelet Activating Factor; Receptors, IgG; Transfusion Reaction | 2013 |
[Value of in-vitro diagnostic tools after anaphylaxis].
Topics: Anaphylaxis; Antibody Specificity; Basophil Degranulation Test; Biomarkers; Epitopes; Germany; Guideline Adherence; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Intradermal Tests; Platelet Activating Factor; Predictive Value of Tests; Reagent Kits, Diagnostic; Secondary Prevention; Tryptases | 2013 |
Anaphylaxis and cardiovascular diseases: a dangerous liaison.
Topics: Anaphylaxis; Cardiovascular Diseases; Histamine; Humans; Inflammation; Mastocytosis; Platelet Activating Factor; Prostaglandins | 2014 |
Markers of anaphylaxis - a systematic review.
Topics: Anaphylaxis; Biomarkers; Histamine; Humans; Platelet Activating Factor; Tryptases | 2018 |
Phenotypes, endotypes and biomarkers in anaphylaxis: current insights.
Topics: Anaphylaxis; Basophils; Biomarkers; Bradykinin; Carboxypeptidases A; Chymases; Complement Activation; Cytokines; Histamine; Humans; Immunoglobulin E; Immunoglobulin G; Interleukin-6; Mast Cells; Phenotype; Platelet Activating Factor; Precision Medicine; Tryptases | 2018 |
Mechanisms of human drug-induced anaphylaxis.
Topics: Anaphylaxis; Animals; Cell Degranulation; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Histamine; Humans; Immunoglobulin E; Immunoglobulin G; Mice; Platelet Activating Factor; Receptors, G-Protein-Coupled | 2021 |
PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.
Topics: Conjunctivitis, Allergic; Eye Diseases; Histamine; Humans; Inflammation; Platelet Activating Factor | 2022 |
13 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and histamine
| Article | Year |
|---|---|
Inhaled budesonide fails to inhibit the PAF-induced increase in plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Blood Platelets; Bronchodilator Agents; Budesonide; Catecholamines; Drug Synergism; Female; Histamine; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Platelet Activating Factor; Platelet Count; Pregnenediones; Reference Values; Thromboxane B2 | 1992 |
The role of histamine in the acute inflammatory responses to intradermal platelet activating factor.
Topics: Benzhydryl Compounds; Double-Blind Method; Drug Hypersensitivity; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Terfenadine | 1991 |
Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans.
Topics: Adult; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Middle Aged; Phthalazines; Platelet Activating Factor; Skin | 1991 |
Terfenadine effect on the bronchoconstriction, dermal response, and leukopenia induced by platelet-activating factor.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Histamine; Humans; Leukopenia; Male; Platelet Activating Factor; Skin Tests; Terfenadine; Time Factors | 1991 |
Inhibition of cutaneous and platelet responses to platelet-activating factor by oral WEB 2086 in man.
Topics: Administration, Oral; Adult; Azepines; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Humans; Injections, Intradermal; Male; Placebos; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Skin; Skin Tests; Triazoles | 1991 |
Experimental pruritus evoked by platelet activating factor (PAF-acether) in human skin.
Topics: Adult; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Female; Histamine; Humans; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pruritus; Pyrilamine; Skin | 1985 |
Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin.
Topics: Administration, Oral; Adolescent; Adult; Cetirizine; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Male; Platelet Activating Factor; Skin | 1988 |
Effect of a PAF antagonist, BN52063, on antigen-induced, acute, and late-onset cutaneous responses in atopic subjects.
Topics: Acute Disease; Adult; Antigens; Dermatitis, Atopic; Female; Histamine; Humans; Lactones; Male; Plant Extracts; Platelet Activating Factor | 1988 |
Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; Female; Histamine; Humans; Male; Platelet Activating Factor; Procaterol; Skin; Skin Tests; Substance P | 1995 |
Effects of H1- and H2-antihistamines on platelet-activating factor and bradykinin-induced inflammatory responses in human skin.
Topics: Administration, Oral; Bradykinin; Cimetidine; Codeine; Double-Blind Method; Doxepin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Platelet Activating Factor; Skin; Terfenadine; Urticaria | 1996 |
Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers.
Topics: Adult; Analysis of Variance; Attention; Cross-Over Studies; Cyproheptadine; Decision Making; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Flicker Fusion; Follow-Up Studies; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Motor Activity; Neuropsychological Tests; Pain Measurement; Platelet Activating Factor; Psychomotor Performance; Reaction Time; Self-Assessment; Skin Tests; Statistics, Nonparametric; Time Factors | 2004 |
A pharmacokinetic/pharmacodynamic model for a platelet activating factor antagonist based on data arising from Phase I studies.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Double-Blind Method; Forecasting; Histamine; Humans; Imidazoles; Injections, Intradermal; Male; Models, Biological; Piperidines; Platelet Activating Factor; Platelet Aggregation; Single-Blind Method; Skin Tests; Time Factors; United Kingdom | 2005 |
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
Topics: Adult; Animals; Biological Availability; Bronchoconstriction; Chromatography, Liquid; Diterpenes; Ginkgo biloba; Ginkgolides; Guinea Pigs; Histamine; Humans; Lactones; Male; Mass Spectrometry; Models, Molecular; Molecular Conformation; Ovalbumin; Plant Extracts; Platelet Activating Factor; Terpenes; Thromboxane B2 | 2006 |
299 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and histamine
| Article | Year |
|---|---|
RP 58802B, a long-acting beta 2-adrenoceptor agonist: assessment of antiasthma activity in the guinea-pig in vivo.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Albuterol; Anesthesia; Animals; Antigens; Asthma; Benzimidazoles; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dextrans; Ethanolamines; Fluorescein-5-isothiocyanate; Guinea Pigs; Histamine; Male; Platelet Activating Factor; Time Factors; Trachea | 1992 |
Reversal of the endotoxin-induced bronchial hyperreactivity to histamine by the platelet activating factor antagonist BN 52021.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Diterpenes; Endotoxins; Ginkgolides; Guinea Pigs; Histamine; Lactones; Male; Platelet Activating Factor; Premedication | 1992 |
Nedocromil sodium prevents in vivo generation of the eosinophilotactic substance induced by PAF but fails to antagonize its effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis, Leukocyte; Eosinophils; Female; Histamine; Leukocyte Count; Lymphokines; Male; Nedocromil; Platelet Activating Factor; Pleurisy; Proteins; Quinolones; Rats; Rats, Inbred Strains | 1992 |
Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Male; Mice; Muscle Contraction; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; SRS-A; Tachykinins; Ureter | 1992 |
[Interference of platelet-activating factor antagonist, BN50739 with the releasing of inflammatory mediators from anaphylactic lung of guinea pig].
Topics: Alveolitis, Extrinsic Allergic; Animals; Azepines; Female; Guinea Pigs; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; Prostaglandins F; SRS-A; Thromboxane B2; Triazoles | 1992 |
Mediator concentrations in bronchoalveolar lavage fluid of patients with mild asymptomatic bronchial asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Autacoids; Bronchoalveolar Lavage Fluid; Cell Count; Chromatography, High Pressure Liquid; Histamine; Humans; Hypersensitivity, Immediate; Leukotrienes; Platelet Activating Factor; Prostaglandin D2 | 1992 |
Stimulation of cyclic AMP production in human alveolar macrophages induced by inflammatory mediators and beta-sympathicomimetics.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Cyclic AMP; Dinoprostone; Female; Histamine; Humans; Isoproterenol; Lung Diseases, Obstructive; Macrophages, Alveolar; Male; Middle Aged; Platelet Activating Factor; Smoking | 1992 |
Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects.
Topics: Adult; Aged; Chlorpheniramine; Chronic Disease; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Kallikreins; Loratadine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Skin; Urticaria | 1992 |
Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized rats.
Topics: Animals; Antigens; Bradykinin; Cetirizine; Cytoplasmic Granules; Female; Histamine; Histamine H1 Antagonists; Leukocyte Count; Male; Mast Cells; Meclizine; Ovalbumin; Platelet Activating Factor; Pleurisy; Rats; Rats, Wistar; Serotonin | 1992 |
Blockade of thromboxane/endoperoxide receptor-mediated responses in the pulmonary vascular bed of the cat by sulotroban.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cats; Endothelins; Female; Histamine; Lung; Male; Norepinephrine; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Sulfonamides | 1992 |
Complex cellular recognition events in acute inflammation.
Topics: Acute-Phase Reaction; Antigens, CD; Bacterial Adhesion; CD11 Antigens; CD18 Antigens; Cell Adhesion Molecules; Endothelium; Histamine; Humans; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Thrombin | 1992 |
Inhibition by azelastine of the effects of platelet-activating factor in lungs from actively sensitised guinea-pigs.
Topics: Animals; Arachidonic Acid; Bronchoconstriction; Guinea Pigs; Histamine; Immunization; Injections, Intra-Arterial; Leukotrienes; Lung; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Artery; Thromboxane B2 | 1992 |
Effects of various inflammatory mediators on eustachian tube patency.
Topics: Animals; Constriction, Pathologic; Dogs; Ear, Middle; Eustachian Tube; Female; Histamine; Male; Otitis Media with Effusion; Platelet Activating Factor; Pressure; SRS-A | 1992 |
Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on PAF-induced airway responses in neonatally immunized rabbits.
Topics: Administration, Inhalation; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Female; Histamine; Immunization; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinolines; Rabbits; SRS-A | 1992 |
Effects of inflammatory mediators on canine airway neuromuscular function.
Topics: Acetylcholine; Animals; Bronchoconstrictor Agents; Dogs; Electrophysiology; Histamine; In Vitro Techniques; Inflammation; Leukotrienes; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Parasympathomimetics; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Respiratory System | 1992 |
Antagonism of platelet-activating factor-induced increase in cytosolic free calcium concentration in human endothelial cells.
Topics: Calcium; Cytosol; Endothelium, Vascular; Epoprostenol; Female; Fura-2; Histamine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pregnancy; Thrombin | 1992 |
Histamine potentiates human platelet aggregation induced by platelet-activating factor.
Topics: Diterpenes; Drug Synergism; Ethylenediamines; Ginkgolides; Histamine; Humans; Lactones; Platelet Activating Factor; Platelet Aggregation | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Effects of NZ-107 on bronchoconstriction in guinea pigs.
Topics: Albuterol; Animals; Asthma; Bronchoconstriction; Cromolyn Sodium; Disease Models, Animal; Guinea Pigs; Histamine; Hydrocortisone; Male; Metyrapone; Platelet Activating Factor; Prednisolone; Pyridazines; Respiration; Time Factors | 1992 |
Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils.
Topics: Azepines; Calcimycin; Calcium; Cytosol; Dinoprostone; Eosinophils; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Lung; Mast Cells; Neutrophils; Piperidines; Platelet Activating Factor; Prostaglandin D2; Secretory Rate; SRS-A; Triazoles | 1992 |
Platelet-activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline-based compounds.
Topics: Animals; Biological Assay; Calcimycin; Histamine; Lipoxygenase Inhibitors; Male; Mast Cells; Molecular Structure; Naphthaleneacetic Acids; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Quinolines; Rats; Rats, Inbred Strains | 1992 |
Inflammatory effects of platelet activating factor (PAF) in equine skin.
Topics: Animals; Capillary Permeability; Chlorpheniramine; Dermatitis; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Horse Diseases; Horses; Indomethacin; Injections, Intradermal; Leukocyte Count; Neutrophils; Platelet Activating Factor; Regional Blood Flow; Skin; Skin Temperature | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines | 1992 |
Priming interactions between platelet activating factor and histamine in the in vivo microcirculation.
Topics: Animals; Cricetinae; Histamine; Histamine Antagonists; Leukopenia; Leukotrienes; Male; Mesocricetus; Microcirculation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1991 |
Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis.
Topics: Acute Disease; Animals; Chronic Disease; Colitis; Dinoprostone; Disease Models, Animal; Histamine; Interleukin-1; Leukotriene B4; Peroxidase; Platelet Activating Factor; Saguinus | 1991 |
Effect of azelastine on platelet-activating factor and antigen-induced pleurisy in rats.
Topics: Animals; Antigens; Female; Histamine; Histamine H1 Antagonists; Leukocytes; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pleural Effusion; Pleurisy; Rats; Rats, Inbred Strains; Serotonin | 1991 |
The induction of plasma leakage in skin by histamine, bradykinin, activated complement, platelet-activating factor and serotonin.
Topics: Animals; Autacoids; Bradykinin; Cell Membrane Permeability; Complement System Proteins; Histamine; Male; Microcirculation; Platelet Activating Factor; Serotonin; Serum Albumin; Sheep; Sheep Diseases; Skin; Skin Diseases; Vasculitis | 1991 |
Effects of anti-inflammatory drugs on rat hind-paw swelling caused by phospholipase A2 from Naja naja atra venom.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Edema; Elapid Venoms; Histamine; Kinins; Leukocytes, Mononuclear; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1991 |
Histamine(H1) antagonists and airway hyperreactivity in the guinea-pig.
Topics: Airway Resistance; Animals; Bronchoconstriction; Guinea Pigs; Histamine; Histamine H1 Antagonists; Injections, Intravenous; Male; Platelet Activating Factor; Respiratory Hypersensitivity; Terfenadine | 1991 |
Histamine, leukotriene D4 and platelet-activating factor in guinea pig passive cutaneous anaphylaxis.
Topics: Acetophenones; Animals; Autacoids; Azepines; Blood Proteins; Bradykinin; Capillary Permeability; Chlorpheniramine; Cimetidine; Guinea Pigs; Histamine; Male; Methysergide; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; SRS-A; Tetrazoles; Triazoles | 1991 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles | 1990 |
Platelet activating factor does not release histamine from human dispersed cutaneous mast cells.
Topics: Antibodies, Anti-Idiotypic; Biomarkers, Tumor; Blood Platelets; Calcimycin; Calcium; Cells, Cultured; Child; Child, Preschool; Energy Metabolism; Histamine; Histamine Release; Humans; Infant; Leukocytes; Lymphokines; Male; Mast Cells; Platelet Activating Factor; Skin; Substance P; Tumor Protein, Translationally-Controlled 1 | 1990 |
Site of anti-inflammatory action of dexamethasone in rabbit skin.
Topics: Animals; Bradykinin; Dactinomycin; Dermatitis, Contact; Dexamethasone; Dinoprostone; Female; Histamine; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Biosynthesis; Rabbits; RNA; Skin; Zymosan | 1991 |
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.
Topics: Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Endothelium, Vascular; Fibrinogen; Histamine; Humans; In Vitro Techniques; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Thrombin; Up-Regulation | 1991 |
Neutrophil chemotactic activity of PAF, histamine and neuromediators in bronchial asthma.
Topics: Adolescent; Adult; Asthma; Chemotaxis, Leukocyte; Histamine; Humans; Middle Aged; Neuropeptides; Neutrophils; Platelet Activating Factor; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Release of tachykinins by histamine, methacholine, PAF, LTD4, and substance P from guinea pig lungs.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Kinetics; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Platelet Activating Factor; SRS-A; Substance P; Tachykinins | 1991 |
Release of mediators from human gastric mucosa and blood in adverse reactions to benzoate.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Asthma; Benzoates; Benzoic Acid; Dermatitis, Atopic; Endoscopy, Gastrointestinal; Female; Food Additives; Gastric Mucosa; Histamine; Histamine Release; Humans; Male; Middle Aged; Monocytes; Platelet Activating Factor; Urticaria | 1991 |
Changes in airway sensitivity to histamine are not necessarily paralleled by changed sensitivity to acetylcholine.
Topics: Acetylcholine; Airway Obstruction; Airway Resistance; Animals; Guinea Pigs; Histamine; Injections, Intravenous; Isoproterenol; Male; Platelet Activating Factor; Respiratory Hypersensitivity; Respiratory System | 1991 |
Effect of long-term infusion of platelet-activating factor on pulmonary responsiveness and morphology in the guinea-pig.
Topics: Animals; Blood Cell Count; Bronchi; Diterpenes; Dose-Response Relationship, Drug; Drug Hypersensitivity; Ginkgolides; Guinea Pigs; Histamine; Lactones; Lung; Male; Platelet Activating Factor; Serum Albumin, Bovine; Time Factors | 1991 |
Vascular permeability increase in the mouse paw during the passive anaphylaxis reaction.
Topics: Animals; Capillary Permeability; Edema; Exudates and Transudates; Female; Histamine; Immunoglobulin E; Immunoglobulins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Serotonin | 1991 |
Role of thromboxane A2 in airway microvascular leakage induced by inhaled platelet-activating factor.
Topics: Administration, Inhalation; Airway Resistance; Animals; Blood Pressure; Capillary Permeability; Dioxanes; Female; Guinea Pigs; Histamine; Methacrylates; Microcirculation; Platelet Activating Factor; Receptors, Prostaglandin; Receptors, Thromboxane; Respiratory System; Thromboxane A2; Thromboxane-A Synthase | 1991 |
Body temperature modulates the effect of platelet-activating factor (PAF) on airways responsiveness in the rabbit.
Topics: Aerosols; Animals; Body Temperature; Bronchoconstriction; Corticosterone; Hematocrit; Histamine; Leukocyte Count; Lung; Neutrophils; Platelet Activating Factor; Platelet Count; Rabbits | 1991 |
Effect of capsaicin on PAF-induced bronchial hyperresponsiveness and pulmonary cell accumulation in the rabbit.
Topics: Anesthesia; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Lung; Nerve Fibers; Platelet Activating Factor; Rabbits; Radioimmunoassay; Serum Albumin, Bovine | 1991 |
Inhibition of neutral endopeptidase potentiates bronchial contraction induced by immune response in guinea pigs in vitro.
Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Serotonin; SRS-A; Thiorphan | 1991 |
Effect of NZ-107 on late-phase airway responses and airway hyperreactivity in guinea pigs.
Topics: Aerosols; Animals; Antigens; Bronchial Hyperreactivity; Bronchoconstriction; Drug Hypersensitivity; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyridazines; Respiratory Hypersensitivity | 1991 |
Eosinophil-eicosanoid interactions: inhibition of eosinophil chemotaxis in vivo by a LTD4-receptor antagonist.
Topics: Animals; Chemotaxis, Leukocyte; Conjunctiva; Eicosanoids; Eosinophils; Guinea Pigs; Histamine; Histocytochemistry; Indium Radioisotopes; Male; Ovalbumin; Platelet Activating Factor; Propionates; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A | 1990 |
The inflammatory actions of platelet activating factor are blocked by levorotatory terbutaline.
Topics: Animals; Blood Pressure; Bradykinin; Dogs; Edema; Histamine; Inflammation; Injections, Intra-Arterial; Lymph; Lymphatic System; Molecular Conformation; Platelet Activating Factor; Receptors, Adrenergic, beta; Terbutaline | 1990 |
Enhancement of the expression of eosinophil IgE receptor (Fc epsilon R2) and its function by platelet-activating factor.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cytotoxicity, Immunologic; Eosinophils; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene B4; Platelet Activating Factor; Receptors, Fc; Receptors, IgE; Schistosoma mansoni; SRS-A | 1990 |
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Injections, Intradermal; Kallikreins; Male; Middle Aged; Platelet Activating Factor; Urticaria | 1990 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Stimulation of neutrophil adherence to vascular endothelial cells by histamine and thrombin and its inhibition by PAF antagonists and dexamethasone.
Topics: Animals; Azepines; Cell Adhesion; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Furans; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombin; Triazoles | 1991 |
Platelet-activating factor (PAF)-induced rhinitis and involvement of PAF in allergic rhinitis in guinea pigs.
Topics: Animals; Capillary Permeability; Capillary Resistance; Evans Blue; Guinea Pigs; Histamine; Male; Nasal Mucosa; Platelet Activating Factor; Rhinitis | 1990 |
Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.
Topics: Aminoquinolines; Animals; Bradykinin; Calcimycin; Calcium; Cimetidine; Endothelium, Vascular; Guinea Pigs; Histamine; Histamine Antagonists; Isoproterenol; Platelet Activating Factor; Pyrilamine; Vena Cava, Inferior | 1990 |
Endothelin 1 causes pulmonary vasodilation in rats.
Topics: Animals; Endothelins; Epoprostenol; Histamine; Lung; Male; Nitric Oxide; Peptides; Platelet Activating Factor; Potassium Channels; Potassium Chloride; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
Multiple mechanisms of xanthine actions on airway reactivity.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Administration, Inhalation; Aerosols; Animals; Blood Pressure; Bronchi; Bronchoconstriction; Bronchodilator Agents; Carbachol; Guinea Pigs; Heart Rate; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Theophylline; Xanthines | 1990 |
Effect of CV-3988, a specific antagonist against platelet activating factor, on homologous passive cutaneous anaphylaxis in the mouse ear.
Topics: Alprostadil; Animals; Antibodies; Blood Vessels; Dinoprostone; Ear, External; Female; Histamine; Immunoglobulin E; Immunoglobulin G; Leukotriene E4; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Permeability; Phospholipid Ethers; Platelet Activating Factor; Serotonin; Skin; SRS-A | 1990 |
Effects of inhaled leukotriene D4 and platelet-activating factor on airway reactivity in normal subjects.
Topics: Administration, Inhalation; Adult; Airway Resistance; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Histamine; Humans; Longitudinal Studies; Male; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Reference Values; Single-Blind Method; SRS-A | 1990 |
Decreased skin response to intradermal platelet-activating factor (PAF-acether) in cancer patients.
Topics: Adult; Female; Histamine; Humans; Male; Middle Aged; Neoplasms; Platelet Activating Factor; Skin | 1990 |
Increased airway reactivity in the guinea-pig follows exposure to intravenous isoprenaline.
Topics: Airway Resistance; Animals; Atropine; Blood Platelets; Bombesin; Bronchodilator Agents; Colforsin; Dopamine; Epinephrine; Guinea Pigs; Histamine; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Platelet Activating Factor; Propranolol; Rabbits; Vagotomy; Vagus Nerve | 1990 |
PAF-induced bronchial hyperresponsiveness in the rabbit: contribution of platelets and airway smooth muscle.
Topics: Aerosols; Animals; Blood Platelets; Bronchi; Bronchoalveolar Lavage Fluid; Carbachol; Guinea Pigs; Histamine; In Vitro Techniques; Leukocyte Count; Lung Compliance; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Platelet Activating Factor; Platelet Activation; Platelet Count; Rabbits; Serum Albumin, Bovine | 1990 |
Endothelin-induced constriction of guinea pig airways: role of platelet-activating factor.
Topics: Animals; Bronchoconstriction; Diterpenes; Endothelins; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Lactones; Male; Muscle, Smooth; Platelet Activating Factor; Trachea | 1990 |
[Bronchial hyperresponsiveness to histamine in guinea pig induced by intravenous administration of platelet activating factor].
Topics: Airway Resistance; Animals; Bronchi; Guinea Pigs; Histamine; Infusions, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds | 1990 |
The action of platelet activating factor and its antagonism by WEB 2086 on human isolated airways.
Topics: Azepines; Bronchi; Histamine; Humans; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Triazines; Triazoles | 1990 |
Inhibitory effects of OKY-046 on spasmogen-induced bronchoconstrictions in sensitized and non-sensitized guinea pigs.
Topics: Acrylates; Animals; Blood Pressure; Bordetella pertussis; Bronchi; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Prostaglandin D2; Thromboxane-A Synthase; Trachea | 1990 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats | 1990 |
Prevention of non-specific airway hyperreactivity after allergen challenge in guinea-pigs by the PAF receptor antagonist SDZ 64-412.
Topics: Allergens; Animals; Azepines; Bronchi; Bronchoalveolar Lavage Fluid; Eosinophils; Guinea Pigs; Histamine; Hypersensitivity; In Vitro Techniques; Isoquinolines; Male; Methylprednisolone; Platelet Activating Factor; Triazines; Triazoles; Vagotomy; Vagus Nerve | 1990 |
Assessment of vascular permeability increase in the mouse by dye leakage during paw edema.
Topics: Animals; Bradykinin; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Edema; Foot; Histamine; Male; Mice; Mice, Inbred ICR; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Tetradecanoylphorbol Acetate | 1990 |
The effect of platelet-activating factor (PAF), histamine, and ethanol on vascular permeability of the guinea pig conjunctiva.
Topics: Animals; Capillary Permeability; Conjunctiva; Edema; Ethanol; Evans Blue; Female; Guinea Pigs; Histamine; Platelet Activating Factor | 1990 |
The effect of platelet-activating factor on [14C]aminopyrine uptake by isolated guinea pig parietal cells.
Topics: Aminopyrine; Analysis of Variance; Animals; Calcium; Carbachol; Gastric Acid; Guinea Pigs; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Platelet Activating Factor; Pyridinium Compounds | 1990 |
Production of active and passive anaphylactic shock in the WBB6F1 mouse, a mast cell-deficient strain.
Topics: Anaphylaxis; Animals; Cyproheptadine; Female; Histamine; Immunization, Passive; Mast Cells; Mice; Mice, Mutant Strains; Phospholipid Ethers; Platelet Activating Factor; Serotonin | 1990 |
The booster injection of antigen during active sensitization of guinea-pig modifies the anti-anaphylactic activity of the PAF antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Azepines; Blood Cell Count; Bronchi; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Histamine; Immunization, Secondary; Immunoglobulin G; Lung; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; Spectrometry, Fluorescence; Thromboxane B2; Triazoles | 1990 |
Anatomic basis for species differences in peripheral lung strip contraction to PAF.
Topics: Animals; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Pleura; Rabbits; Species Specificity; SRS-A | 1990 |
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Capillary Permeability; Complement C5; Complement C5a, des-Arginine; Dinoprostone; Drug Synergism; Edema; Histamine; Inflammation; Injections, Intradermal; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins E; Rabbits; Rats; Rats, Inbred Lew; Skin; Species Specificity; Substance P | 1985 |
Pulmonary responses to bronchoconstrictor agonists in the mouse.
Topics: Animals; Histamine; Indomethacin; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Mice; Mice, Inbred C57BL; Norepinephrine; Platelet Activating Factor; Plethysmography; Propranolol; Prostaglandins; Reference Values; Serotonin; SRS-A; Substance P | 1988 |
The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Diacylglycerol Kinase; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Substance P; Thiazoles | 1989 |
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.
Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea | 1989 |
Limited interference of specific Paf antagonists with hyper-responsiveness to Paf itself of lungs from actively sensitized guinea-pigs.
Topics: Animals; Azepines; Bronchi; Female; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity; In Vitro Techniques; Lung; Male; Muscle, Smooth; Perfusion; Platelet Activating Factor; Pulmonary Edema; SRS-A; Trachea; Triazines; Triazoles | 1989 |
Vasodepression ex vivo after administration of inflammatory mediators in vivo in the rat.
Topics: Alprostadil; Animals; Biological Factors; Bradykinin; Endotoxins; Epoprostenol; Escherichia coli; Female; Histamine; Inflammation; Norepinephrine; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Serotonin; SRS-A; Substance P; Vasoconstriction | 1989 |
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis.
Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, Thin Layer; Cycloheximide; Drug Synergism; Endothelium, Vascular; Epoprostenol; Histamine; Humans; Interleukin-1; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Thrombin; von Willebrand Factor | 1989 |
The effects of TMB-8 on the shape changes of vascular endothelial cells resulting from exposure to various inflammatory agents.
Topics: Animals; Bradykinin; Calcimycin; Calcium Channel Blockers; Dinoprostone; Endothelium, Vascular; Gallic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inflammation; Leukotrienes; Platelet Activating Factor; Vena Cava, Inferior | 1989 |
Selenium deficiency inhibits prostacyclin release and enhances production of platelet activating factor by human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Glutathione Peroxidase; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Platelet Activating Factor; Selenium; Thrombin; Umbilical Veins | 1989 |
Modulation of arterial endothelial permeability: studies on an in vitro model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Albumins; Animals; Aorta, Thoracic; Arteries; Bradykinin; Calcimycin; Catalase; Endothelium, Vascular; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Permeability; Platelet Activating Factor; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate | 1989 |
Effect of chronic administration of platelet-activating factor (PAF) in the guinea-pig and the rat.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Infusion Pumps; Interleukin-1; Interleukin-2; Lung; Lymphocyte Activation; Lymphocytes; Platelet Activating Factor; Rats | 1989 |
Flow-cytometric analysis of increased IgE uptake by normal eosinophils following activation with PAF-acether and other inflammatory mediators.
Topics: Antigens, Differentiation, B-Lymphocyte; Eosinophils; Flow Cytometry; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene B4; Platelet Activating Factor; Receptors, Fc; Receptors, IgE; Time Factors | 1989 |
Regulation of phosphoinositide turnover in endothelium from human pulmonary artery, aorta and umbilical vein. Antagonistic action on the beta-adrenoceptor coupled adenylate cyclase system.
Topics: Adenylyl Cyclases; Cells, Cultured; Endothelium, Vascular; Histamine; Humans; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Receptors, Adrenergic, beta; Thrombin | 1989 |
Evidence of PAF-acether metabolic pathway activation in antigen challenge of upper respiratory airways.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Histamine; Humans; Leukotriene B4; Male; Nasal Mucosa; Nasal Provocation Tests; Platelet Activating Factor; Pollen; Radioallergosorbent Test; Rhinitis, Allergic, Seasonal; Skin Tests; Therapeutic Irrigation | 1989 |
Inhibition of bradykinin-induced bronchoconstriction in the guinea-pig by a synthetic B2 receptor antagonist.
Topics: Acetylcholine; Animals; Blood Pressure; Bombesin; Bradykinin; Bronchodilator Agents; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Platelet Activating Factor; Receptors, Bradykinin; Receptors, Neurotransmitter; Respiration; Time Factors | 1989 |
Platelet-activating factor causes goblet cell depletion in the conjunctiva.
Topics: Animals; Capillary Permeability; Conjunctiva; Guinea Pigs; Histamine; In Vitro Techniques; Leukocytes; Leukotriene E4; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; SRS-A | 1989 |
[The blocking action of platelet-activating factor (PAF) on the calcium currents of the atrial fibers in the frog and guinea pig].
Topics: Animals; Atrial Function; Calcium Channel Blockers; Calcium Channels; Diterpenes; Ginkgolides; Guinea Pigs; Heart; Heart Atria; Histamine; In Vitro Techniques; Lactones; Membrane Potentials; Myocardial Contraction; Platelet Activating Factor; Rana ridibunda | 1989 |
Modification of allergen-induced airway obstruction and airway hyperresponsiveness in an allergic rabbit model by the selective platelet-activating factor antagonist, BN 52021.
Topics: Airway Obstruction; Allergens; Animals; Bronchial Spasm; Diterpenes; Ginkgolides; Histamine; Lactones; Lung; Lung Compliance; Plant Extracts; Platelet Activating Factor; Rabbits; Respiratory Hypersensitivity | 1989 |
Functional changes in the microcirculation of alloxan-induced diabetic rats.
Topics: Acetylcholine; Animals; Arterioles; Diabetes Mellitus, Experimental; Histamine; Male; Microcirculation; Norepinephrine; Papaverine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; Tyramine; Vasoconstriction; Venules | 1989 |
Effect of long-term administration of platelet-activating factor on pulmonary responsiveness and morphology in the guinea pig.
Topics: Animals; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Platelet Activating Factor; Respiratory Hypersensitivity; Time Factors | 1989 |
PAF-induced contraction of canine trachea mediated by 5-hydroxytryptamine in vivo.
Topics: Animals; Atropine; Dogs; Histamine; Muscle Contraction; Parasympathetic Nervous System; Platelet Activating Factor; Serotonin; Trachea | 1989 |
Role of platelet activating factor in the endotoxin induced tracheal hyperreactivity to histamine in the guinea pig.
Topics: Animals; Asthma; Endotoxins; Guinea Pigs; Histamine; Male; Platelet Activating Factor; Trachea | 1989 |
Regional and time-dependent effects of inflammatory mediators on airway microvascular permeability in the guinea pig.
Topics: Animals; Bronchi; Capillary Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Larynx; Leukotrienes; Male; Nasal Mucosa; Platelet Activating Factor; Respiratory System; Trachea | 1989 |
Tracheal responsiveness to histamine, PAF-acether and acetylcholine in normal and actively ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Animals; Female; Guinea Pigs; Histamine; Immunization; Indomethacin; Isometric Contraction; Male; Ovalbumin; Platelet Activating Factor; Quinacrine; Trachea | 1989 |
Platelet-activating factor (Paf) antagonist, WEB 2086, protects against Paf-induced hypotension in Macaca fascicularis.
Topics: Animals; Azepines; Blood Pressure; Dose-Response Relationship, Drug; Histamine; Macaca fascicularis; Male; Platelet Activating Factor; Triazines; Triazoles | 1989 |
The effect of Paf antagonists on bronchial hyperresponsiveness induced by Paf, propranolol or indomethacin.
Topics: Acetylcholine; Animals; Azepines; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lactones; Male; Phospholipid Ethers; Platelet Activating Factor; Propranolol; Respiratory Hypersensitivity; Triazines; Triazoles | 1989 |
Influence of platelet-activating factor on leukotriene D4-induced contractions of the guinea pig parenchymal strip.
Topics: Acetylcholine; Animals; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Potassium Chloride; SRS-A | 1989 |
Inhibition by histamine of platelet-activating-factor-induced neutrophil chemotaxis in bronchial asthma.
Topics: Asthma; Chemotaxis, Leukocyte; Histamine; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor | 1989 |
Platelet-activating factor-induced functional changes in the guinea pig trachea in vitro.
Topics: Animals; Drug Hypersensitivity; Guinea Pigs; Histamine; Hypersensitivity; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Receptors, Histamine H2; Trachea | 1989 |
Histamine formed in stimulated human platelets is cytoplasmic.
Topics: Blood Platelets; Cytoplasm; Female; Histamine; Humans; Male; Phosphatidylethanolamines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Saponins; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Role of platelet-activating factor (PAF) in the bronchopulmonary alterations and beta-adrenoceptor function induced by endotoxin.
Topics: Animals; Biological Assay; Endotoxins; Guinea Pigs; Histamine; Isoproterenol; Lung; Male; Muscle Contraction; Muscle Relaxation; Platelet Activating Factor; Receptors, Adrenergic, beta | 1988 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
The effect of platelet-activating factor on histamine and muscarinic receptor function in guinea pig airways.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Lung; Male; Muscle Contraction; Phosphatidylinositols; Platelet Activating Factor; Pressure; Receptors, Histamine; Receptors, Muscarinic; Respiration; Trachea | 1988 |
Agonist-induced polyphosphoinositide breakdown in cultured human endothelial and vascular smooth muscle cells.
Topics: Aorta; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Histamine; Humans; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Phosphatidylinositols; Platelet Activating Factor; Thrombin; Vasoconstrictor Agents | 1988 |
Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate.
Topics: Adenosine Triphosphate; Bradykinin; Cells, Cultured; Endothelium; Epoprostenol; Histamine; Humans; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Activating Factor; Receptors, Bradykinin; Receptors, Histamine H1; Receptors, Neurotransmitter | 1985 |
[Azelastine inhibits bronchoconstriction induced by histamine and leukotriene C4].
Topics: Airway Resistance; Animals; Bronchi; Constriction, Pathologic; Guinea Pigs; Histamine; Histamine H1 Antagonists; Phthalazines; Platelet Activating Factor; Pyridazines; SRS-A | 1988 |
[Cardiodepressive effect of platelet activating factor].
Topics: Action Potentials; Aminopyridines; Animals; Calcium; Guinea Pigs; Heart; Heart Atria; Histamine; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Platelet Activating Factor; Potassium | 1989 |
trans-2,5-Bis-(3,4,5-trimethoxyphenyl)tetrahydrofuran. An orally active specific and competitive receptor antagonist of platelet activating factor.
Topics: Animals; Benzofurans; Benzopyrans; Blood Platelets; Bradykinin; Capillary Permeability; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Furans; Histamine; Humans; Lignans; Magnesium; Mathematics; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sodium; Thiazoles | 1985 |
The mast cell and theophylline in asthma.
Topics: Adenosine Triphosphate; Asthma; Chemotactic Factors; Chondroitin Sulfates; Cyclic AMP; Heparin; Histamine; Humans; Mast Cells; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D; SRS-A; Theophylline | 1985 |
[Mediators of immediate anaphylactic reactions].
Topics: Anaphylaxis; Chemotactic Factors; Enzymes; Histamine; Humans; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Proteoglycans; SRS-A | 1985 |
Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.
Topics: Animals; Chromones; Diphenhydramine; Dose-Response Relationship, Drug; Guinea Pigs; Hematocrit; Hemorrhage; Histamine; Injections, Intravenous; Leukotriene B4; Male; Phospholipid Ethers; Plasma; Platelet Activating Factor; SRS-A; Thiazoles; Time Factors | 1986 |
Experimental eosinophilia and inflammation--the effect of various inflammatory mediators and chemoattractants.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Blood Proteins; Bradykinin; Carrageenan; Cell Movement; Chemotactic Factors; Chemotactic Factors, Eosinophil; Disease Models, Animal; Eosinophil Granule Proteins; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine; Inflammation; Isoenzymes; Male; Neutrophils; Peroxidase; Peroxidases; Platelet Activating Factor; Ribonucleases; Time Factors; Trichinellosis | 1986 |
Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists.
Topics: Alprazolam; Anaphylaxis; Animals; Benzodiazepines; Benzofurans; Benzopyrans; Diphenhydramine; Guinea Pigs; Histamine; Lignans; Male; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Comparative effects of drugs on leukotrienes-, PAF-acether- and histamine- induced contractions of guinea-pig lung parenchymal strips.
Topics: Animals; Chromones; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene B4; Lung; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A | 1986 |
Production of platelet-activating factor by chick retina.
Topics: Acetylcholine; Amino Acids; Animals; Calcimycin; Chickens; Diacylglycerol Cholinephosphotransferase; Dopamine; Epinephrine; Histamine; In Vitro Techniques; Kinetics; Platelet Activating Factor; Retina | 1986 |
Effect of platelet-activating factor on beta-adrenoceptors in human lung.
Topics: Cell Membrane; Dihydroalprenolol; Histamine; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Methacholine Chloride; Methacholine Compounds; Platelet Activating Factor; Receptors, Adrenergic, beta; Trachea | 1987 |
The effect of platelet activating factor on pulmonary beta-adrenoceptors.
Topics: Animals; Guinea Pigs; Histamine; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Lung; Male; Pindolol; Platelet Activating Factor; Receptors, Adrenergic, beta; Trachea | 1987 |
Microvascular leakage to platelet activating factor in guinea-pig trachea and bronchi.
Topics: Animals; Bronchi; Capillary Permeability; Dose-Response Relationship, Drug; Endothelium; Female; Guinea Pigs; Histamine; In Vitro Techniques; Leukocyte Count; Platelet Activating Factor; Platelet Count; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Time Factors; Trachea; Venules | 1987 |
The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition.
Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Cyclooxygenase Inhibitors; Drug Interactions; Electrocardiography; Female; Hemodynamics; Histamine; Histamine Antagonists; Indomethacin; Infusions, Intravenous; Male; Platelet Activating Factor; Promethazine; Rabbits | 1987 |
Increased airways responsiveness to histamine induced by platelet activating factor in the guinea-pig: possible role of lipoxygenase metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Atropine Derivatives; Bronchi; Female; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase; Male; Masoprocol; Platelet Activating Factor; Pyrazoles; Vagotomy | 1988 |
Lipoxygenase metabolites as mediators of platelet activating factor-induced increased airways responsiveness to histamine in the guinea-pig.
Topics: Animals; Asthma; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; Lipoxygenase; Platelet Activating Factor; Respiratory System | 1988 |
Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig.
Topics: Animals; Female; Guinea Pigs; Histamine; Hydroxyquinolines; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Lung Compliance; Male; Platelet Activating Factor; Quinolines; SRS-A | 1988 |
[Nasal response to chemical mediators in nasal allergy].
Topics: Adolescent; Adult; Airway Resistance; Biological Factors; Female; Histamine; Humans; Male; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Nose; Platelet Activating Factor; Prostaglandin D2; Rhinitis, Allergic, Perennial; Sneezing; SRS-A | 1988 |
Effects of platelet-activating factor on rat airways.
Topics: Acetylcholine; Animals; Blood Pressure; Bronchi; Drug Interactions; Histamine; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1988 |
Active immunization induces lung hyperresponsiveness in the guinea pig. Pharmacologic modulation and triggering role of the booster injection.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchial Spasm; Capillary Permeability; Female; Guinea Pigs; Histamine; Immunization; Immunization, Secondary; Kinetics; Lung; Male; Ovalbumin; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Respiratory Hypersensitivity; SRS-A; Thromboxane B2 | 1988 |
Influence of vasoactive agents on cytoplasmic free calcium in vascular endothelial cells.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cattle; Cells, Cultured; Cytoplasm; Endothelium, Vascular; Histamine; Humans; Platelet Activating Factor; Protein Kinase C; Thrombin; Vasodilator Agents | 1988 |
Bronchospasmolytic effects of RU 42173.
Topics: Acetylcholine; Albuterol; Animals; Benzimidazoles; Bronchi; Bronchial Spasm; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Isoproterenol; Male; Methacholine Compounds; Platelet Activating Factor; Trachea | 1988 |
BN-52021 protects guinea-pig from heart anaphylaxis.
Topics: Anaphylaxis; Animals; Diterpenes; Ginkgolides; Guinea Pigs; Heart; Heart Rate; Histamine; Lactones; Male; Platelet Activating Factor; Thromboxane B2 | 1988 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
Lymphatic smooth muscle responses to leukotrienes, histamine and platelet activating factor.
Topics: Administration, Topical; Animals; Histamine; Lymphatic System; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A | 1988 |
Negative inotropic effect of platelet-activating factor: association with a decrease in intracellular sodium activity.
Topics: Action Potentials; Algorithms; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Histamine; Myocardial Contraction; Myocardium; Platelet Activating Factor; Sodium | 1988 |
New pharmacological data on the bronchospasmolytic activity of bamifylline.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Bronchodilator Agents; Guinea Pigs; Histamine; Male; Platelet Activating Factor; SRS-A; Theophylline; Thromboxane A2 | 1988 |
Lack of involvement of leukotriene and platelet activating factor in passive cutaneous anaphylaxis in rats.
Topics: Animals; Capillary Permeability; Female; Histamine; Male; Passive Cutaneous Anaphylaxis; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; SRS-A | 1988 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Age-dependent differential development of leukotactic and vasoactive responsiveness to acute inflammatory mediators.
Topics: Aging; Animals; Blood; Bradykinin; Capillary Permeability; Chemotaxis, Leukocyte; Dinoprostone; Female; Histamine; Inflammation; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandins E; Rabbits; Zymosan | 1986 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Serotonin; SRS-A; Thromboxane B2; Trachea | 1987 |
Characterization of inflammatory mediator release from purified human lung mast cells.
Topics: Antibodies, Anti-Idiotypic; Cell Separation; Histamine; Humans; Immunoglobulin E; Kinetics; Lung; Mast Cells; Platelet Activating Factor; Pneumonia; Prostaglandin D2; Prostaglandins D; SRS-A; Thromboxane B2 | 1986 |
Comparative effects of platelet activating factor, leukotriene D4 and histamine on guinea pig trachea, bronchus and lung parenchyma.
Topics: Airway Resistance; Animals; Bronchi; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lung; Platelet Activating Factor; Pulmonary Circulation; SRS-A; Trachea | 1987 |
Effect of platelet-activating factor on aerosol histamine responsiveness in awake sheep.
Topics: Aerosols; Airway Resistance; Animals; Dose-Response Relationship, Drug; Histamine; Infusions, Intravenous; Lung; Lung Compliance; Lung Volume Measurements; Platelet Activating Factor; Sheep | 1987 |
Interference by the novel PAF-acether antagonist WEB 2086 with the bronchopulmonary responses to PAF-acether and to active and passive anaphylactic shock in guinea-pigs.
Topics: Anaphylaxis; Animals; Azepines; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indicators and Reagents; Leukopenia; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Radioimmunoassay; Respiratory System; Spectrometry, Fluorescence; Thrombocytopenia; Thromboxane B2; Triazines; Triazoles | 1987 |
Exudative, cellular and humoral reactions to platelet-activating factor (PAF-acether) in the pleural cavity of rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Kinetics; Leukocyte Count; Male; Platelet Activating Factor; Pleural Effusion; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2 | 1986 |
The responsiveness of rabbit bronchial rings to antigen, AGEPC and histamine.
Topics: Animals; Antigens; Atropine; Bronchi; Carbachol; Chlorpheniramine; Female; Histamine; Immunoglobulin E; Immunoglobulin G; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rabbits | 1986 |
Actions of disodium cromoglycate (DSCG) on human skin responses to histamine, codeine and Paf-acether.
Topics: Adult; Asthma; Codeine; Cromolyn Sodium; Histamine; Humans; Mast Cells; Platelet Activating Factor; Skin | 1985 |
Characterization of cutaneous vascular permeability induced by platelet-activating factor in guinea pigs and rats and its inhibition by a platelet-activating factor receptor antagonist.
Topics: Animals; Benzofurans; Benzopyrans; Binding Sites; Bradykinin; Cell Membrane Permeability; Cyclooxygenase Inhibitors; Drug Interactions; Female; Guinea Pigs; Histamine; Indomethacin; Lignans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Skin; Species Specificity; Tritium | 1985 |
Mediators and asthma.
Topics: Adenosine; Asthma; Bradykinin; Bronchial Spasm; Chemotactic Factors; Chemotaxis, Leukocyte; Histamine; Humans; Lipoxygenase; Nerve Tissue Proteins; Platelet Activating Factor; Prostaglandins; SRS-A | 1985 |
Permeability-increasing ability of PAF-acether in rat skin.
Topics: Animals; Capillary Permeability; Cell Membrane Permeability; Dose-Response Relationship, Drug; Histamine; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Zymosan | 1985 |
An investigation of the involvement of platelet activating factor in the non-histamine immediate hypersensitivity reaction in the rat peritoneal cavity.
Topics: Animals; Blood Proteins; Histamine; Hypersensitivity, Immediate; Peritoneal Cavity; Platelet Activating Factor; Rats | 1985 |
Histamine and leukotriene-independent guinea-pig anaphylactic shock unaccounted for by Paf-acether.
Topics: Acetophenones; Anaphylaxis; Animals; Catechols; Chromones; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Masoprocol; Muscle Contraction; Platelet Activating Factor; SRS-A | 1985 |
Evidence for a direct effect on vascular permeability of platelet-activating factor induced hemoconcentration in the guinea pig.
Topics: Animals; Calcium Channel Blockers; Capillary Permeability; Guinea Pigs; Hematocrit; Histamine; Male; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane-A Synthase | 1985 |
[Mediators of inflammation. Their nature and their role].
Topics: Anti-Inflammatory Agents; Bradykinin; Histamine; Humans; Inflammation; Leukotriene B4; Platelet Activating Factor; Prostaglandins; Serotonin | 1982 |
Hypotensive and vasodilatory activity of (+/-) 1-o-octadecyl-2-acetyl glyceryl-3-phosphorylcholine in the normotensive rat.
Topics: Acetylcholine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Histamine; Infusions, Intra-Arterial; Injections, Intravenous; Isoproterenol; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Renin; Vasodilation | 1983 |
The role of antihypertensive polar renomedullary lipid in the pathogenesis of hypertension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dinoprostone; Dogs; Epoprostenol; Female; Histamine; Hypertension, Renal; Kidney; Kidney Medulla; Male; Norepinephrine; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Thiazoles | 1984 |
On the nature of the vasoreactivity depressing factor (VDF) in inflammation and anaphylaxis in the rat and mouse.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprostadil; Anaphylaxis; Animals; Anti-Inflammatory Agents; Epoprostenol; Female; Histamine; Indomethacin; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; Serotonin; Vasopressins | 1984 |
Phospholipids, particularly platelet-activating factor (PAF-acether), in experimental bronchoconstriction.
Topics: Anaphylaxis; Animals; Blood Platelets; Bronchi; Guinea Pigs; Histamine; In Vitro Techniques; Lipid Metabolism; Lung; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Rabbits; SRS-A; Thromboxanes | 1983 |
Morphologic basis of increased vascular permeability induced by acetyl glyceryl ether phosphorylcholine.
Topics: Animals; Blood Platelets; Female; Histamine; Male; Mast Cells; Muscles; Neutrophils; Permeability; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin; Veins; Venules | 1984 |
Byssinosis: some unanswered questions.
Topics: Arachidonic Acid; Arachidonic Acids; Byssinosis; Forced Expiratory Volume; Histamine; Humans; Lysophosphatidylcholines; Platelet Activating Factor; SRS-A | 1982 |
Platelet-activating factor-mediated contraction of rabbit lung strips: pharmacologic modulation.
Topics: Acetylcholine; Anaphylaxis; Animals; Complement C5; Complement C5a; Histamine; Immunoglobulin E; In Vitro Techniques; Lung; Muscle Contraction; Platelet Activating Factor; Rabbits | 1983 |
Vasoactive properties of acetyl glyceryl ether phosphorylcholine and analogues.
Topics: Animals; Blood Platelets; Capillary Permeability; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Lysophosphatidylcholines; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Skin Tests; Vasoconstriction | 1982 |
Relaxation of the guinea-pig trachea induced by platelet-activating factor and by serotonin.
Topics: Acetylcholine; Animals; Aspirin; Blood Platelets; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lysophosphatidylcholines; Male; Methysergide; Muscle Relaxation; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Serotonin; Trachea | 1982 |
Rat serum sickness: possible role of inflammatory mediators allowing deposition of immune complexes in the glomerular basement membrane.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Basement Membrane; Disease Models, Animal; Histamine; Kidney Glomerulus; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Sickness | 1982 |
Contraction of guinea pig ileal smooth muscle by acetyl glyceryl ether phosphorylcholine.
Topics: Animals; Blood Coagulation Factors; Guinea Pigs; Histamine; Ileum; Kinetics; Lysophosphatidylcholines; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor | 1981 |
Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airway inflammation in guinea pigs.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Capsaicin; Dextrans; Dyspnea; Fluorescein-5-isothiocyanate; Guinea Pigs; Histamine; Leukocytes; Male; Ovalbumin; Platelet Activating Factor | 1993 |
Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats.
Topics: Aminophylline; Animals; Antigens; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Female; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity; Leukocyte Count; Leukotriene B4; Male; Muscle Relaxation; Muscle, Smooth; Passive Cutaneous Anaphylaxis; Phosphodiesterase Inhibitors; Platelet Activating Factor; Purinones; Rats; Rats, Wistar; Superoxides; Trachea | 1993 |
Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event.
Topics: Animals; Antigens, CD; CD18 Antigens; Cell Adhesion; Cromolyn Sodium; Histamine; Inflammation; Leukocytes; Male; Mast Cells; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Time Factors; Venules | 1994 |
Effects of antiallergic agents including levocabastine on experimental rhinitis in rats.
Topics: Acetylcholine; Animals; Antigens, Helminth; Ascaris; Histamine; Histamine H1 Antagonists; Ketotifen; Male; Nasal Mucosa; Piperidines; Platelet Activating Factor; Rats; Rats, Wistar; Rhinitis; Substance P | 1994 |
Platelet activating factor potentiates rat paw oedema induced by different phlogogen agents.
Topics: Animals; Bradykinin; Carrageenan; Cellulose; Dextrans; Dinoprostone; Diterpenes; Drug Synergism; Edema; Ginkgolides; Histamine; Inflammation Mediators; Lactones; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Verapamil | 1994 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig.
Topics: Acute Disease; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophilia; Guinea Pigs; Histamine; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mifepristone; Neutrophils; Platelet Activating Factor; Pneumonia; Skin | 1995 |
The antagonistic effects of khellactones on platelet-activating factor, histamine, and leukotriene D4.
Topics: Animals; Coumarins; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; In Vitro Techniques; Lactones; Leukotriene D4; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship | 1995 |
Pleural fluid eosinophils suppress local IgE-mediated protein exudation in rats.
Topics: Animals; Blood Proteins; Dinitrophenols; Eosinophilia; Eosinophils; Exudates and Transudates; Female; Histamine; Hypersensitivity; Immunoglobulin E; Lipopolysaccharides; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pleural Effusion; Rats; Rats, Wistar; Serotonin; Serum Albumin, Bovine | 1995 |
Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase.
Topics: Animals; Arginine; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Histamine; Inflammation Mediators; Mucins; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Secretory Rate; Superoxides; Trachea; Tumor Necrosis Factor-alpha | 1995 |
Platelet-activating factor stimulates gastric acid secretion in isolated rabbit gastric glands.
Topics: Aminopyrine; Animals; Azepines; Biological Transport; Calcium; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Famotidine; Fluorescent Dyes; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rabbits; Thiazoles; Thienopyridines; Triazoles; Verapamil | 1995 |
Contribution of platelet activating factor (PAF) in histamine-induced model of nasal allergy in rats.
Topics: Animals; Disease Models, Animal; Histamine; Male; Nasal Mucosa; Permeability; Platelet Activating Factor; Rats; Rats, Wistar; Rhinitis, Allergic, Perennial | 1995 |
High precision measurement of electrical resistance across endothelial cell monolayers.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Electric Impedance; Endothelium, Vascular; Histamine; Humans; Leukotriene C4; Platelet Activating Factor; Thrombin; Umbilical Veins | 1995 |
Investigations on the role of inflammatory and anti-inflammatory agents on the treatment of murine B cell leukemia by recombinant human interleukin-2.
Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Dinoprostone; Freund's Adjuvant; Histamine; Inflammation; Interleukin-2; Leukemia, B-Cell; Lipopolysaccharides; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Recombinant Proteins; Substance P | 1993 |
Inhaled A23187 produces a preferential sensitization to substance P.
Topics: Animals; Bronchial Provocation Tests; Bronchoconstriction; Calcimycin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Lung Volume Measurements; Male; Neprilysin; Platelet Activating Factor; SRS-A; Substance P; Thiorphan | 1993 |
Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Leukotriene D4; Male; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Receptors, Neurokinin-1; Skin; Substance P; Ureter | 1993 |
Activation of capsaicin-sensitive sensory fibers modulates PAF-induced bronchial hyperresponsiveness in anesthetized guinea pigs.
Topics: Anesthesia; Animals; Azepines; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Nerve Fibers; Platelet Activating Factor; Ruthenium Red; Serum Albumin, Bovine; Time Factors; Triazoles | 1993 |
Effect of heparin and a low-molecular weight heparinoid on PAF-induced airway responses in neonatally immunized rabbits.
Topics: Airway Resistance; Animals; Animals, Newborn; Anticoagulants; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chondroitin Sulfates; Dermatan Sulfate; Female; Glycosaminoglycans; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Histamine; Immunization; Lung; Lung Compliance; Male; Platelet Activating Factor; Polyglutamic Acid; Rabbits; Respiratory Function Tests | 1993 |
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Interleukin-1; Male; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Receptors, Interleukin-1; Receptors, Neurokinin-1; Regional Blood Flow; Substance P; Xenon Radioisotopes | 1993 |
Preclinical efficacy of emedastine, a potent, selective histamine H1 antagonist for topical ocular use.
Topics: Administration, Topical; Anaphylaxis; Animals; Benzimidazoles; Capillary Permeability; Conjunctiva; Conjunctivitis, Allergic; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Ophthalmic Solutions; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Corticosterone secretion in response to serotonin and ACTH by perfused adrenal of normal and athymic nude mice.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Dose-Response Relationship, Drug; Histamine; Hydrocortisone; Male; Mice; Mice, Inbred ICR; Mice, Nude; p-Methoxy-N-methylphenethylamine; Perfusion; Platelet Activating Factor; Reproducibility of Results; Secretory Rate; Serotonin; Thymus Gland | 1995 |
Antibronchospastic activity of MEN10,627, a novel tachykinin NK2 receptor antagonist, in guinea-pig airways.
Topics: Acetylcholine; Air Pressure; Amino Acid Sequence; Animals; Biphenyl Compounds; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; Hypnotics and Sedatives; In Vitro Techniques; Male; Molecular Sequence Data; Muscle, Smooth; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Respiratory System | 1995 |
Mechanisms underlying acute mast cell-induced leukocyte rolling and adhesion in vivo.
Topics: Animals; Cell Adhesion; Cell Degranulation; Chemotaxis, Leukocyte; Histamine; Leukocytes; Leukotrienes; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1995 |
Characterization of a behavioral model for peripherally evoked itch suggests platelet-activating factor as a potent pruritogen.
Topics: Animals; Azepines; Female; Guinea Pigs; Histamine; Male; Platelet Activating Factor; Pruritus; Pyridinium Compounds; Triazoles | 1995 |
Methoctramine induces nonspecific airway hyperresponsiveness in vivo.
Topics: Aerosols; Albuterol; Animals; Arachidonic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Diamines; Drug Synergism; Gallamine Triethiodide; Guinea Pigs; Histamine; Male; Muscarinic Antagonists; Ovalbumin; Parasympatholytics; Piperazines; Piperidines; Platelet Activating Factor; Propranolol; Receptors, Muscarinic | 1994 |
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.
Topics: Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bronchial Hyperreactivity; Bronchial Spasm; Bronchodilator Agents; Capillary Permeability; Guinea Pigs; Hemodynamics; Histamine; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram | 1994 |
Comparison of the anti-inflammatory properties of formoterol, salbutamol and salmeterol in guinea-pig skin and lung.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Bronchoalveolar Lavage Fluid; Ethanolamines; Formoterol Fumarate; Granulocytes; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Infant, Newborn; Lung; Male; Neutrophils; Platelet Activating Factor; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; Skin | 1993 |
Effect of beta 2-adrenoceptor agonists against platelet-activating factor-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Animals; Bronchoconstriction; Bronchodilator Agents; Capillary Permeability; Ethanolamines; Female; Formoterol Fumarate; Guinea Pigs; Histamine; Platelet Activating Factor; Receptors, Adrenergic, beta-2 | 1993 |
Rolipram inhibits airway microvascular leakage induced by platelet-activating factor, histamine and bradykinin in guinea-pigs.
Topics: Aminophylline; Animals; Blood Pressure; Bradykinin; Bronchi; Capillary Permeability; Drug Interactions; Evans Blue; Guinea Pigs; Histamine; Microcirculation; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyrrolidinones; Rolipram; Trachea | 1993 |
[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.
Topics: Anaphylaxis; Animals; Benzocycloheptenes; Blood Pressure; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Muscle Contraction; Muscle, Smooth; Piperidines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1994 |
The effect of immune and inflammatory mediators on growth of Lucilia cuprina larvae in vitro.
Topics: Animals; Autacoids; Bradykinin; Cytokines; Diptera; Histamine; Larva; Platelet Activating Factor; Serotonin | 1994 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs.
Topics: Animals; Benzoquinones; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capillary Permeability; Chromones; Drug Interactions; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Leukocyte Count; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Pressure; Respiratory Physiological Phenomena; Respiratory System; Thromboxane A2 | 1994 |
Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits.
Topics: Administration, Inhalation; Airway Resistance; Animals; Binding Sites; Blood Platelets; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dose-Response Relationship, Drug; Eosinophils; Female; Histamine; Immunization; Isoquinolines; Male; Neutrophils; Platelet Activating Factor; Rabbits | 1994 |
Effect of PAF on rat lung vascular permeability: role of platelets and polymorphonuclear leucocytes.
Topics: Animals; Blood Platelets; Capillary Permeability; Histamine; Lung; Male; Neutrophils; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Serotonin | 1994 |
Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells.
Topics: Aerosols; Albumins; Animals; Bronchial Hyperreactivity; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Inflammation; Luminescent Measurements; Lung; Male; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Platelet Activating Factor; Therapeutic Irrigation; Trachea | 1993 |
Nasal allergen challenge generates 1-0-hexadecyl-2-lyso-sn-glycero-3-phosphocholine.
Topics: Acute-Phase Reaction; Adolescent; Adult; Albumins; Analysis of Variance; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Histamine; Humans; Male; Nasal Lavage Fluid; Nasal Provocation Tests; Phospholipases A; Platelet Activating Factor; Rhinitis, Allergic, Seasonal; Time Factors; Tosylarginine Methyl Ester | 1994 |
A comparison of the actions of platelet activating factor (PAF) antagonists WEB 2170 and WEB 2086 in the horse.
Topics: Animals; Azepines; Capillary Permeability; Dose-Response Relationship, Drug; Histamine; Horses; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Skin; Triazoles | 1993 |
Inflammatory effects of ozone in the upper airways of subjects with asthma.
Topics: Adolescent; Adult; Asthma; Female; Histamine; Humans; Inflammation; Interleukin-8; Leukocyte Count; Leukotriene B4; Male; Nasal Lavage Fluid; Ozone; Platelet Activating Factor; Respiratory Mechanics; Respiratory System | 1994 |
Synthesis and release of platelet-activating factor and eicosanoids in human endothelial cells induced by different agonists.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Blood Platelets; Calcimycin; Cells, Cultured; Dinoprostone; Endothelins; Endothelium, Vascular; Epoprostenol; Histamine; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Serotonin; Thrombin; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
The effect of platelet-activating factor on the responsiveness of the human nasal airway.
Topics: Administration, Inhalation; Adult; Airway Resistance; Blood Proteins; Bradykinin; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Free Radicals; Histamine; Humans; Nasal Cavity; Nasal Lavage Fluid; Platelet Activating Factor; Ribonucleases; Vitamin E | 1993 |
Platelet activating factor and histamine effects in synovial blood flow evaluated by laser-Doppler flowmetry.
Topics: Animals; Azepines; Female; Histamine; Laser-Doppler Flowmetry; Male; Platelet Activating Factor; Rabbits; Regional Blood Flow; Synovial Membrane; Triazoles; Vasoconstriction | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
No increase in plasma histamine during PAF-induced airway obstruction in allergic asthmatics.
Topics: Adult; Airway Resistance; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Forced Expiratory Volume; Histamine; Humans; Leukocyte Count; Male; Maximal Midexpiratory Flow Rate; Platelet Activating Factor; Platelet Count; Skin Tests; Vital Capacity | 1993 |
Platelet activating factor enhances receptor-operated Ca(++)-influx and subsequent prostacyclin synthesis in human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Fura-2; Histamine; Humans; Imidazoles; Kinetics; Platelet Activating Factor; Platelet Aggregation Inhibitors; Spectrometry, Fluorescence; Thrombin; Umbilical Veins | 1993 |
[Effect of Asthremedin on bronchial hyperresponsiveness (BHR) to histamine induced by intravenous administration of platelet activating factor (PAF) in guinea pigs].
Topics: Adrenocorticotropic Hormone; Animals; Bronchial Hyperreactivity; Guinea Pigs; Histamine; Histamine Antagonists; Hydrocortisone; Infusions, Intravenous; Male; Platelet Activating Factor | 1993 |
Interference of the PAF receptor antagonist, PCA 4248, with the rat pleurisy evoked by inflammatory mediators or allergen.
Topics: Allergens; Animals; Bradykinin; Dihydropyridines; Edema; Eosinophils; Exudates and Transudates; Female; Histamine; Hypersensitivity; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin | 1993 |
Platelet activating factor-induced microvascular permeability increases in the cat hindlimb.
Topics: Animals; Azepines; Capillary Permeability; Cats; Cimetidine; Diphenhydramine; Endothelium, Vascular; Hindlimb; Histamine; Isoproterenol; Leukocyte Count; Leukocytes; Platelet Activating Factor; Triazoles | 1993 |
Regional blood flow volume in the eustachian tube.
Topics: Animals; Blood Volume; Dogs; Dose-Response Relationship, Drug; Eustachian Tube; Histamine; Otitis Media with Effusion; Platelet Activating Factor; Regional Blood Flow; SRS-A | 1993 |
Priming with murine recombinant interleukin-5 resulted in the augmentation of PAF-induced airway hyperresponsiveness to histamine in guinea pigs.
Topics: Aminophylline; Animals; Bronchoconstriction; Guinea Pigs; Histamine; Interleukin-5; Leukocyte Count; Male; Naphthyridines; Phosphodiesterase Inhibitors; Platelet Activating Factor; Purinones; Recombinant Proteins | 1993 |
Comparative effects of tetrandrine and berbamine on guineapig airway microvascular leakage induced by platelet-activating factor and other allergic mediators.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Benzylisoquinolines; Bradykinin; Capillary Permeability; Disease Models, Animal; Female; Guinea Pigs; Histamine; Hypersensitivity; Male; Platelet Activating Factor; Respiratory System; SRS-A | 1993 |
Leukotrienes and histamine mediate IgE-dependent contractions of human bronchi: pharmacological evidence obtained with tissues from asthmatic and non-asthmatic subjects.
Topics: Adult; Aged; Asthma; Bronchi; Cyclooxygenase Inhibitors; Female; Histamine; Histamine Antagonists; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Receptors, Immunologic; SRS-A | 1993 |
The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit.
Topics: Airway Resistance; Anaphylaxis; Animals; Azepines; Basophil Degranulation Test; Blood Pressure; Chlorpheniramine; Cimetidine; Histamine; Immunoglobulin E; Leukocyte Count; Lung Compliance; Platelet Activating Factor; Rabbits; Serotonin; Tidal Volume; Triazoles | 1993 |
Inhibition of nitric oxide synthase attenuates primed microvascular permeability in the in vivo microcirculation.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Cromolyn Sodium; Dextrans; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Histamine; Inflammation; Macrophage-1 Antigen; Male; Mast Cells; Mesocricetus; Microcirculation; Microscopy, Video; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor | 1995 |
Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC).
Topics: Animals; Cell Movement; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Growth Substances; Histamine; Intercellular Signaling Peptides and Proteins; Male; Mice; Neutrophils; Platelet Activating Factor; Rats; Selectins | 1996 |
Pharmacological characterization of Sephadex-induced oedema in rat paws: predominant role of serotonin and platelet-activating factor.
Topics: Animals; Bradykinin; Cyclosporine; Dexamethasone; Dextrans; Diterpenes; Edema; Ginkgolides; Histamine; Immunosuppressive Agents; Inflammation Mediators; Injections, Intravenous; Lactones; Male; Methysergide; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Polyenes; Rats; Serotonin; Serotonin Antagonists; Sirolimus | 1996 |
Tissue levels of histamine, PAF-acether and lysopaf-acether in carrageenan-induced granuloma in rats.
Topics: Animals; Carrageenan; Granuloma; Histamine; Inflammation Mediators; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1996 |
Involvement of protein kinase C in hypoxia-induced desensitization of the beta-adrenergic system in human endothelial cells.
Topics: Adrenergic beta-Agonists; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Histamine; Humans; Hypoxia; Isoproterenol; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Receptors, Adrenergic, beta; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Platelet activating factor: release from colonic mucosa in patients with ulcerative colitis and its effect on colonic secretion.
Topics: Adult; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coculture Techniques; Colitis, Ulcerative; Colon; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; Electrophysiology; Female; Histamine; Humans; Intestinal Mucosa; Lipoxygenase Inhibitors; Male; Organ Culture Techniques; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin | 1996 |
Regulation of platelet-activating factor production in gastric epithelial cells.
Topics: Animals; Calcimycin; Calcium; Carbachol; Epithelium; Gastric Mucosa; Histamine; Humans; Ionophores; Parasympathomimetics; Platelet Activating Factor; Rabbits; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Effects of selective phosphodiesterase inhibitors on platelet-activating factor- and antigen-induced airway hyperreactivity, eosinophil accumulation, and microvascular leakage in guinea pigs.
Topics: Animals; Asthma; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Male; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyrrolidinones; Respiratory System; Rolipram | 1996 |
Microvascular mechanisms of histamine-induced potentiation of leukocyte adhesion evoked by chemoattractants.
Topics: Amino Acid Sequence; Animals; Azepines; Chemotactic Factors; Drug Synergism; Female; Histamine; Leukocytes; Leukotriene B4; Microcirculation; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Wistar; Splanchnic Circulation; Triazoles | 1995 |
Role of lipoxygenase metabolites in platelet-activating factor- and antigen-induced bronchial hyperresponsiveness and eosinophil infiltration.
Topics: Animals; Benzofurans; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; Humans; Leukotriene Antagonists; Lipoxygenase; Lipoxygenase Inhibitors; Male; Ovalbumin; Platelet Activating Factor; Pulmonary Eosinophilia; Quinolines | 1995 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |
Histamine augments VCAM-1 expression on IL-4- and TNF-alpha-stimulated human umbilical vein endothelial cells.
Topics: Amanitins; Antibodies, Blocking; Antigens, CD; Cell Adhesion; Cells, Cultured; Cimetidine; Eosinophils; Histamine; Histamine Antagonists; Humans; Immunohistochemistry; Integrin alpha4; Interleukin-4; Piperidines; Platelet Activating Factor; Pyrilamine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1996 |
Release of histamine in whole blood by oxygen radicals: division between specific and unspecific processes.
Topics: Cell Adhesion Molecules; Electron Spin Resonance Spectroscopy; Fluorescent Antibody Technique, Indirect; Granulocytes; Histamine; Histamine Release; Humans; Hypoxanthine; L-Lactate Dehydrogenase; L-Selectin; Monocytes; Platelet Activating Factor; Reactive Oxygen Species; Spin Trapping; Xanthine Oxidase | 1996 |
CV6209 inhibits airway wall thickening and airway hyperresponsiveness to histamine induced by intravenous administration of platelet-activating factor in guinea pigs.
Topics: Airway Resistance; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine Antagonists; Lung; Male; Platelet Activating Factor; Pyridinium Compounds | 1996 |
ZG-1494 alpha, a novel platelet-activating factor acetyltransferase inhibitor from Penicillium rubrum, isolation, structure elucidation andbiological activity.
Topics: Acetyltransferases; Animals; Enzyme Inhibitors; Histamine; HL-60 Cells; Humans; Molecular Structure; Penicillium; Platelet Activating Factor; Protein Binding; Pyrrolidinones; Rabbits; Receptors, Glucocorticoid | 1996 |
High-density lipoprotein inhibits the synthesis of platelet-activating factor in human vascular endothelial cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Arachidonic Acid; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Histamine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Phospholipases A; Platelet Activating Factor; Thrombin; Umbilical Veins | 1996 |
The effect of the selective PAF antagonist CIS-19 on PAF- and antigen-induced bronchoconstriction, microvascular leakage and bronchial hyperreactivity in guinea-pigs.
Topics: Airway Resistance; Animals; Antigens; Bronchoconstriction; Bronchoconstrictor Agents; Capillary Permeability; Guinea Pigs; Histamine; Male; Methacholine Chloride; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Hypersensitivity; Substance P; Tetrahydronaphthalenes | 1997 |
Anti-inflammatory and bronchodilator properties of KF19514, a phosphodiesterase 4 and 1 inhibitor.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Antigens; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dogs; Eosinophils; Guinea Pigs; Histamine; Hypersensitivity; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthyridines; Phosphodiesterase Inhibitors; Platelet Activating Factor; Rabbits; Tumor Necrosis Factor-alpha | 1997 |
Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins.
Topics: Animals; Cell Movement; Crystallization; Endothelium, Vascular; Gout; Histamine; Macrophage-1 Antigen; Male; Mast Cells; Mice; Neutrophils; Peritonitis; Platelet Activating Factor; Selectins; Uric Acid | 1997 |
Role of circulating blood components and thromboxane in anaphylactic vasoconstriction in isolated canine lungs.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascaris suum; Blood Pressure; Capillary Permeability; Dogs; Eicosanoids; Female; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Leukocyte Count; Lung; Male; Platelet Activating Factor; Pulmonary Circulation; Thromboxanes; Vasoconstriction | 1997 |
Effect of Y-24180, a long-acting antagonist to platelet-activating factor (PAF), on PAF-induced reactions: a relationship between the partial structure of the compound and its duration of the action.
Topics: Acetylcholine; Administration, Oral; Animals; Azepines; Binding Sites; Blood Platelets; Bradykinin; Bronchial Hyperreactivity; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Injections, Intravenous; Leukotriene D4; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Structure-Activity Relationship; Triazoles | 1997 |
Platelet activating factor causes hyperconstriction at the inflammatory coronary lesions in pigs in vivo.
Topics: Animals; Coronary Vasospasm; Coronary Vessels; Dinoprost; Drug Synergism; Histamine; Interleukin-1; Isoquinolines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Pyridinium Compounds; Serotonin; Swine; Tetrahydroisoquinolines; Vasoconstriction | 1997 |
Inhibitor effect of apafant on bronchopulmonary responses to platelet activating factor and to antigen in rats.
Topics: Animals; Azepines; Bronchi; Histamine; Hypersensitivity, Immediate; In Vitro Techniques; Lung; Male; Organ Size; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Circulation; Rats; Rats, Inbred BN; Rats, Wistar; Triazoles | 1997 |
Platelet activating factor revisited.
Topics: Asthma; Basophils; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Humans; Leukotrienes; Lung; Neutrophil Activation; Platelet Activating Factor; Pulmonary Gas Exchange | 1997 |
Effects of S-salbutamol on human isolated bronchus.
Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor | 1998 |
Immunoglobulin E-dependent active fatal anaphylaxis in mast cell-deficient mice.
Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Azepines; Female; Haptens; Histamine; Immunoglobulin E; Interleukin-4; Mast Cells; Mice; Mice, Mutant Strains; Penicillin V; Platelet Activating Factor; Triazoles | 1998 |
Release of granule proteins from human eosinophils stimulated with mast-cell mediators.
Topics: Blood Proteins; Calcium; Chemotactic Factors, Eosinophil; Cytokines; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Histamine; Humans; Inflammation Mediators; Kinetics; Leukotriene B4; Leukotriene C4; Mast Cells; Platelet Activating Factor; Prostaglandin D2; Ribonucleases | 1998 |
Human corneal epithelial cell functional responses to inflammatory agents and their antagonists.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bradykinin; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Collagenases; Cytokines; DNA Primers; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Histamine; Histamine Antagonists; Humans; Inositol Phosphates; Keratins; Matrix Metalloproteinase 1; Middle Aged; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Bradykinin; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1998 |
Effect of overproduction of interleukin 5 on dinitrofluorobenzene-induced allergic cutaneous response in mice.
Topics: Animals; Capillary Permeability; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Drug Hypersensitivity; Female; Histamine; Immunoglobulin E; Interleukin-5; Mice; Mice, Inbred C3H; Mice, Transgenic; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Serotonin | 1999 |
Responses of guinea-pig lung parenchymal strips to tracheobronchial lavage fluid from horses affected with summer pasture-associated obstructive pulmonary disease.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Dinoprostone; Guinea Pigs; Histamine; Horse Diseases; Horses; In Vitro Techniques; Leukotriene D4; Lung; Lung Diseases, Obstructive; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Poaceae; Prostaglandin Antagonists; Quinolines; Reference Values; Seasons; Trachea; Xanthenes; Xanthones | 1998 |
Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine.
Topics: Animals; Blood Platelets; Calcium; Histamine; Histamine H1 Antagonists; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrilamine; Rabbits; Thromboxane B2 | 1997 |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase | 1999 |
Assessment of the mechanism of juxtacrine activation and adhesion of leukocytes in liver microcirculation.
Topics: Animals; Cell Adhesion; Enzyme Inhibitors; Gene Expression Regulation; Guanidines; Histamine; Intercellular Adhesion Molecule-1; Kinetics; Leukocytes; Leukotriene C4; Liver Circulation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microcirculation; P-Selectin; Platelet Activating Factor; Venules | 1999 |
Comparison of weal and flare responses to platelet activating factor (PAF) and histamine, and the ultrastructural effects of PAF in the skin of atopic and normal subjects.
Topics: Case-Control Studies; Dermatitis, Atopic; Dose-Response Relationship, Immunologic; Histamine; Humans; Hypersensitivity; Microscopy, Electron; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Serum Albumin; Skin | 1999 |
Effect of inflammatory mediators on the electrophysiology of the human oviduct.
Topics: Alprostadil; Calcium; Cells, Cultured; Chlorides; Dinoprostone; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Ion Channels; Leukotriene B4; Membrane Potentials; Piperidines; Platelet Activating Factor | 1999 |
Experimental studies on guanosine 3',5'-cyclic monophosphate levels and airway responsiveness of the novel phosphodiesterase type 5 inhibitor SR 265579 in guinea-pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoconstriction; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Epithelial Cells; Guinea Pigs; Histamine; In Vitro Techniques; Isoenzymes; Male; Muscle Tonus; Phosphodiesterase Inhibitors; Platelet Activating Factor; Respiratory System; Trachea | 1999 |
Inhaled NO reaches distal vasculatures to inhibit endothelium- but not leukocyte-dependent cell adhesion.
Topics: Administration, Inhalation; Animals; Capillary Permeability; Cats; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Hydrogen Peroxide; Leukocytes; Leukotriene B4; Lung; Microscopy, Video; Nitric Oxide; Oxadiazoles; Oxidants; Oxidative Stress; P-Selectin; Platelet Activating Factor; Quinoxalines | 1999 |
Actions and interactions of ADP, 5- HT, histamine and PAF on equine platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Interactions; Histamine; Horses; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 2000 |
Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice.
Topics: Administration, Oral; Anaphylaxis; Animals; Body Weight; Disease Models, Animal; Female; Fever; Food Hypersensitivity; Histamine; Injections, Intraperitoneal; Interferon-gamma; Interleukin-4; Mast Cells; Mice; Mice, Mutant Strains; Organ Size; Ovalbumin; Platelet Activating Factor; Th2 Cells | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arginine; Blood Pressure; Cardiac Output; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Rate; Histamine; Indomethacin; Isoenzymes; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Ventilation; Serotonin; Signal Transduction; Sulfonamides | 2001 |
Protective effect of silymarin in antigen challenge- and histamine-induced bronchoconstriction in in vivo guinea-pigs.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Protective Agents; Silymarin; Substance P; Time Factors | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.
Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors | 2002 |
Thymoquinone protects against experimental colitis in rats.
Topics: Acetic Acid; Animals; Benzoquinones; Colitis; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Histamine; Male; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Rectum | 2003 |
Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production.
Topics: Amides; Angiopoietin-1; Animals; Bradykinin; Capillary Permeability; Cattle; Cell Adhesion; Cell Line; Cells, Cultured; Endothelium, Vascular; Histamine; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lung; Neutrophils; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Thrombin | 2003 |
Microvascular reactivity in experimental diabetes: responses of male and female rats.
Topics: Acetylcholine; Angiotensin II; Animals; Body Weight; Bradykinin; Diabetes Mellitus, Experimental; Estrous Cycle; Female; Histamine; Hypoglycemic Agents; Insulin; Male; Microcirculation; Nitroprusside; Norepinephrine; Organ Size; Platelet Activating Factor; Rats; Rats, Wistar; Sex Characteristics; Uterus; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
IL-4 primes human endothelial cells for secondary responses to histamine.
Topics: Calcium; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Histamine; Humans; Interleukin-1; Interleukin-4; Oncostatin M; Oxytocics; Peptides; Platelet Activating Factor; Receptors, Histamine; Signal Transduction; Tumor Necrosis Factor-alpha; Umbilical Veins; Up-Regulation | 2003 |
Pathogenesis of esophageal rings in eosinophilic esophagitis.
Topics: Acetylcholine; Adult; Allergens; Antimicrobial Cationic Peptides; Chemotactic Factors; Eosinophilia; Eosinophils; Esophagitis; Esophagus; Gastroenteritis; Histamine; Humans; Intestinal Mucosa; Mast Cells; Muscle Contraction; Muscle Fibers, Skeletal; Platelet Activating Factor | 2005 |
In vivo PAF-induced airway eosinophil accumulation reduces bronchial responsiveness to inhaled histamine.
Topics: Administration, Inhalation; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Guanidines; Guinea Pigs; Histamine; Male; Platelet Activating Factor | 2005 |
TNF-alpha induces the late-phase airway hyperresponsiveness and airway inflammation through cytosolic phospholipase A(2) activation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cytosol; Disease Models, Animal; Enzyme Activation; Histamine; Inflammation; Leukotriene B4; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Knockout; Phospholipases A; Platelet Activating Factor; Pulmonary Eosinophilia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Inhibition of platelet-activating factor biosynthesis by adenosine and histamine in human neutrophils: involvement of cPLA2alpha and reversal by lyso-PAF.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Antihypertensive Agents; Cells, Cultured; Enzyme Inhibitors; Group IV Phospholipases A2; Histamine; Humans; Leukotrienes; MAP Kinase Signaling System; Membrane Lipids; Neutrophils; Phenethylamines; Phospholipases A; Phospholipids; Phosphorylation; Platelet Activating Factor; Pyrrolidines; Receptor, Adenosine A2A; Receptors, Formyl Peptide; Receptors, Histamine H2 | 2006 |
Intravenously administered oligonucleotides can be delivered to conducting airway epithelium via the bronchial circulation.
Topics: Animals; Biological Transport; Bradykinin; Bronchi; Cell Nucleus; Cystic Fibrosis; Cytoplasm; Epithelial Cells; Extravasation of Diagnostic and Therapeutic Materials; Gene Expression; Genetic Therapy; Histamine; Injections, Intravenous; Liposomes; Male; Mice; Mice, Inbred BALB C; Microcirculation; Microscopy, Fluorescence; NF-kappa B; Oligonucleotides; Platelet Activating Factor; Respiratory Mucosa; Transfection | 2006 |
Mechanism for acute oral desensitization to antibiotics.
Topics: Administration, Oral; Anaphylaxis; Animals; Anti-Bacterial Agents; Desensitization, Immunologic; Disease Models, Animal; Drug Hypersensitivity; Female; Histamine; Immunoglobulin E; Mast Cells; Mice; Penicillin V; Platelet Activating Factor | 2006 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Edema; Foot; Hindlimb; Histamine; Indomethacin; Injections, Intraperitoneal; Leukocytes; Lipoxins; Male; Mice; Neutrophil Infiltration; Oligopeptides; Platelet Activating Factor; Pleurisy; Receptors, Lipoxin | 2006 |
Involvement of platelet activating factor, histamine and serotonin in acute lethal shock induced by Candida albicans water-soluble extracellular polysaccharide fraction (CAWS) in mice.
Topics: Acute Disease; Animals; Candida albicans; Capillary Permeability; Epinephrine; Histamine; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Platelet Activating Factor; Polysaccharides; Serotonin; Shock, Septic; Vasculitis | 2007 |
Platelet-activating factor, PAF acetylhydrolase, and anaphylaxis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anaphylaxis; Histamine; Humans; Platelet Activating Factor; Tryptases | 2008 |
High dose of lipopolysaccharide pre-treatment prevents OVA-induced anaphylactic decreases in rectal temperature in the immunized mice.
Topics: Allergens; Anaphylaxis; Animals; Antibody Formation; Body Temperature; Histamine; Immunization; Immunoglobulin E; Immunoglobulin G; Lipopolysaccharides; Male; Mice; Ovalbumin; Platelet Activating Factor; Rectum | 2008 |
PAF, rather than histamine, participates in mouse anaphylactic hypotension.
Topics: Anaphylaxis; Animals; Blood Pressure; Diphenhydramine; Histamine; Histamine H1 Antagonists; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Receptors, Histamine H1 | 2008 |
Peanuts can contribute to anaphylactic shock by activating complement.
Topics: Adrenergic beta-Antagonists; Allergens; Anaphylaxis; Animals; Arachis; Basophils; Cell Degranulation; Chymases; Complement Activation; Complement C3a; Histamine; Humans; Immunoglobulin E; Interleukin-4; Macrophages; Mast Cells; Mice; Mice, Inbred BALB C; Peanut Hypersensitivity; Platelet Activating Factor; Propranolol; Receptors, IgG; Toll-Like Receptors | 2009 |
Anaphylaxis to a self-peptide in the absence of mast cells or histamine.
Topics: Adjuvants, Immunologic; Anaphylaxis; Animals; Bacterial Toxins; Bordetella pertussis; Encephalomyelitis, Autoimmune, Experimental; Glycoproteins; Histamine; Histidine Decarboxylase; Immunization; Immunoglobulin E; Interleukin-4; Mast Cells; Mice; Mice, Knockout; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Platelet Activating Factor; Pyridinium Compounds; Th1 Cells; Th2 Cells | 2009 |
Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models.
Topics: Animals; Capillary Permeability; Cells, Cultured; Chemotaxis, Leukocyte; Conjunctiva; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Leukotriene B4; Male; Mast Cells; Ovalbumin; Peritoneal Cavity; Piperidines; Platelet Activating Factor; Pyridines; Rats; Rats, Wistar | 2010 |
Efficacy and tolerability of rupatadine at four times the recommended dose against histamine- and platelet-activating factor-induced flare responses and ex vivo platelet aggregation in healthy males.
Topics: Administration, Oral; Adult; Area Under Curve; Cyproheptadine; Histamine; Histamine H1 Antagonists; Humans; Injections, Intradermal; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pruritus; Skin; Young Adult | 2010 |
Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Cross-Sectional Studies; Female; Histamine; Humans; Male; Middle Aged; Platelet Activating Factor; Tryptases; Young Adult | 2013 |
Platelet-activating factor (PAF) induces wheal and flare skin reactions independent of mast cell degranulation.
Topics: Adult; Cell Degranulation; Codeine; Female; Germany; Histamine; Histamine Release; Humans; Injections, Intradermal; Male; Mast Cells; Microdialysis; Platelet Activating Factor; Reference Values; Sampling Studies; Skin; Skin Tests; Urticaria; Young Adult | 2013 |
Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF, PMA or A23187 in C6 glioma cells.
Topics: Animals; Calcimycin; Cell Line, Tumor; Enzyme Activation; Fluorenes; Histamine; Phosphatidylcholines; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipase D; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 2013 |
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Release; Inflammation; Lactones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Peritoneum; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Reptilian Proteins; Snake Venoms; Terfenadine | 2013 |
Serum tryptase determination in patients with acute allergic reactions.
Topics: Anaphylaxis; Female; Histamine; Humans; Male; Platelet Activating Factor; Tryptases | 2013 |
Reply: To PMID 23040367.
Topics: Anaphylaxis; Female; Histamine; Humans; Male; Platelet Activating Factor; Tryptases | 2013 |
Rupatadine inhibits inflammatory mediator release from human laboratory of allergic diseases 2 cultured mast cells stimulated by platelet-activating factor.
Topics: Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cyproheptadine; Histamine; Humans; Interleukin-8; Mast Cells; Platelet Activating Factor; Substance P; Tumor Necrosis Factor-alpha | 2013 |
Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine.
Topics: Anaphylaxis; Animals; Arterial Pressure; Cardiac Output; Diphenhydramine; Hemodynamics; Histamine; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Vascular Resistance; Vasoconstriction; Vasodilation | 2014 |
C-reactive protein specifically enhances platelet-activating factor-induced inflammatory activity in vivo.
Topics: Animals; C-Reactive Protein; Disease Models, Animal; Edema; Histamine; Inflammation Mediators; Male; Phospholipids; Platelet Activating Factor; Protein Binding; Rats; Rats, Wistar; Recombinant Proteins; Scavenger Receptors, Class E; Serotonin | 2014 |
The responses of pulmonary and systemic circulation and airway to anaphylactic mediators in anesthetized BALB/c mice.
Topics: Anaphylaxis; Animals; Arterial Pressure; Dose-Response Relationship, Drug; Histamine; Leukotriene C4; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Prostaglandin D2; Serotonin; Vascular Resistance; Vasoconstriction; Vasodilation | 2016 |
The Responses of Pulmonary and Systemic Circulation and Airway to Allergic Mediators in Anesthetized Rats.
Topics: Anesthesia; Animals; Arterial Pressure; Blood Circulation; Histamine; Hypersensitivity; Inflammation Mediators; Leukotriene C4; Lung; Male; Platelet Activating Factor; Prostaglandin D2; Rats, Sprague-Dawley; Serotonin; Vascular Resistance; Vasoconstriction | 2016 |
Characterization of platelet-activating factor-induced cutaneous edema and erythema in dogs.
Topics: Animals; Azepines; Dogs; Edema; Erythema; Histamine; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, G-Protein-Coupled; Skin; Skin Diseases; Triazoles | 2016 |
Influence of glucocorticoids on time-of-day-dependent variations in IgE-, histamine-, and platelet-activating factor-mediated systemic anaphylaxis in different mouse strains.
Topics: Anaphylaxis; Animals; Circadian Rhythm; Disease Models, Animal; Glucocorticoids; Histamine; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Platelet Activating Factor; Species Specificity | 2018 |
The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock.
Topics: Anaphylaxis; Animals; Capillary Permeability; Cytokine TWEAK; Endothelial Cells; Histamine; Mice; Mice, Knockout; Platelet Activating Factor; TWEAK Receptor | 2020 |
The TWEAK/Fn14 axis in anaphylactic shock.
Topics: Anaphylaxis; Apoptosis; Fibroblast Growth Factors; Histamine; Humans; Platelet Activating Factor | 2020 |
Rupatadine ameliorated ulcerative colitis in rats via modulation of platelet-activatiweng factor/interleukin-6/vascular endothelial growth factor signalling pathway.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Colon; Cyproheptadine; Histamine; Interleukin-6; Male; Platelet Activating Factor; Rats; Rats, Wistar; Signal Transduction; Vascular Endothelial Growth Factor A | 2022 |
Clinacanthus nutans aqueous leaves extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Histamine; Immunoglobulin E; Immunoglobulin G; Interleukin-4; Interleukin-6; Mast Cells; Mice; Mice, Inbred C57BL; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2023 |
Mechanisms for hypothermia during anaphylactic hypotension in awake rats.
Topics: Anaphylaxis; Animals; Histamine; Hypotension; Hypothermia; Platelet Activating Factor; Rats; Wakefulness | 2023 |