1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with glucose, (beta-d)-isomer in 144 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (glucose, (beta-d)-isomer) | Trials (glucose, (beta-d)-isomer) | Recent Studies (post-2010) (glucose, (beta-d)-isomer) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 21,956 | 883 | 10,747 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (31.94) | 18.7374 |
| 1990's | 82 (56.94) | 18.2507 |
| 2000's | 10 (6.94) | 29.6817 |
| 2010's | 6 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, K; Mochizuki, K; Ohta, M; Shiota, M; Sugano, T | 1 |
| Mabuchi, K; Masuzawa, Y; Ojima-Uchiyama, A; Sugiura, T; Waku, K | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Donigi-Gale, D; Edwards, R; Norman, KE; Rossi, AG; Shoupe, TS; Williams, TJ | 1 |
| Askaa, J; Bjerrum, OW; Borregaard, N; Kjeldsen, L | 1 |
| Bautista, AP; Spitzer, JJ | 1 |
| Cramer, R; Knowles, A; Menegazzi, R; Patriarca, P; Zabucchi, G | 1 |
| Blom, M; Roos, D; Tool, AT; Verhoeven, AJ | 2 |
| Blackburn, WD; Chatham, WW; Heck, LW | 2 |
| Blom, M; Koenderman, L; Kok, PT; Roos, D; Tool, AT; Verhoeven, AJ | 2 |
| Kantorski, J; Tchórzewski, H | 1 |
| Faccioli, LH; Kay, AB; Moqbel, R; Nourshargh, S; Sehmi, R; Williams, FM; Williams, TJ | 1 |
| Balsinde, J; Fernández, B | 1 |
| Chang, FY; Chang, ML; Chou, CT; Shaio, MF | 1 |
| Forn, J; García-Rafanell, J; Gómez, LA; Merlos, M; Vericat, L | 1 |
| Flower, RJ; Peers, SH | 1 |
| Benveniste, J; Bidault, J; Jurgens, P; Leyravaud, S; Ninio, E | 1 |
| Hayashi, M; Imai, Y; Oh-ishi, S | 2 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 2 |
| Brain, SD; Buckley, TL; Rampart, M; Williams, TJ | 1 |
| Fukuda, T; Masuzawa, Y; Sugiura, T; Waku, K | 1 |
| Lim, WH; Stewart, AG | 1 |
| Arm, JP; Burke, LA; Crea, AE; Lee, TH; Spur, BW; Wilkinson, JR | 1 |
| Aliaga, M; Barbara, M; Bruniquel, F; Caillol, V; Delhon, A; N'Guyen, X; Puech, L; Tarayre, JP; Tisné-Versailles, J; Tisseyre, N | 1 |
| Koenderman, L; Roos, D; Tool, AT; Verhoeven, AJ | 2 |
| Benveniste, J; Chignard, M; Coëffier, E; Delautier, D; Denizot, Y; Le Couedic, JP | 1 |
| Baker, RC; Clay, KL; Tucker, M | 1 |
| Roth, DR; Zwahlen, RD | 1 |
| Hsueh, W; Sun, XM; Torre-Amione, G | 1 |
| Roth, DR; Wyder-Walther, M; Zwahlen, RD | 1 |
| Masuzawa, Y; Ojima-Uchiyama, A; Sugiura, T; Waku, K | 1 |
| Durstin, M; Gomez-Cambronero, J; Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Benveniste, J; Dulioust, A; Haye-Legrand, I; Meslier, N; Roubin, R; Vivier, E | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Bruijnzeel, PL; Kok, PT; Warringa, RA | 1 |
| Fradin, A; Henson, PM; Maclouf, J; Murphy, RC; Vausbinder, L; Zirrolli, JA | 1 |
| Henderson, WR; Martin, TR; Merritt, TL; Raugi, G | 1 |
| McDonald, JW; Smallbone, BW; Taylor, NE | 1 |
| Colton, CA; Gilbert, DL | 1 |
| Cordeiro, RN; Hatmi, M; Lima, MC; Malanchère, E; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Bozza, PT; Cordeiro, RS; Dias, PM; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Bruynzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Beckman, JK; Gay, JC; Lukens, JN; Zaboy, KA | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Augustine, NH; Hill, HR; McFall, TL; Zimmerman, GA | 1 |
| Bitter-Suermann, D; Englberger, W; Hadding, U | 1 |
| Mata, R; Muniain, MA; Pérez, JJ; Pozuelo, F; Rodríguez, MC; Rodríguez, MD; Romero, A | 1 |
| Detty, DM; Leslie, CC | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Calhoun, W; Carlson, RP; Chang, J | 1 |
| Angle, MJ; McManus, LM; Pinckard, RN | 1 |
| Bruynzeel, PL; Hameling, ML; Koenderman, L; Kok, PT; Verhagen, J | 1 |
| Bittner, C; Parnham, MJ | 1 |
| Flower, RJ; Parente, L | 1 |
| Gerdin, B; Lundberg, C; Smedegøard, G | 1 |
| Colditz, IG; Movat, HZ | 2 |
| Benveniste, J; Drapier, JC; Petit, JF; Roubin, R | 1 |
| Alonso, F; Gómez-Cambronero, J; Iñarrea, P; Sánchez Crespo, M | 1 |
| Benveniste, J; Mencia-Huerta, JM | 1 |
| Alonso, F; Mato, JM; Sánchez-Crespo, M | 1 |
| Emilsson, A; Sundler, R | 1 |
| Albert, DH; Snyder, F | 1 |
| Baud, L; Hagege, J; Perez, J; Satriano, JA; Schlondorff, D | 1 |
| Andres, JL; Clay, KL; Henson, PM; Lynch, J; Murphy, RC | 1 |
| Chilton, FH; Ellis, JM; Olson, SC; Wykle, RL | 1 |
| Benveniste, J; Poitevin, B; Roubin, R | 1 |
| Benveniste, J; Landes, A; Mencia-Huerta, JM; Roubin, R | 1 |
| Czarneztki, BM | 1 |
| Beijer, L; Holt, BJ; Holt, PG; Rylander, R | 1 |
| Colwell, JA; Espinoza, GA; Lopes-Virella, MF; Sherwood, T; Shuler, C; Virella, G; Winocour, P | 1 |
| Benveniste, J; Mencia-Huerta, JM; Morgat, JL; Roubin, R | 1 |
| Alonso, F; Gil, MG; Mato, JM; Sánchez-Crespo, M | 1 |
| Au, BT; Collins, PD; Williams, TJ | 1 |
| Auer, DE; Mills, PC; Ng, JC; Seawright, AA | 1 |
| Hellewell, PG; Teixeira, MM; Williams, TJ | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Turner, NC; Wood, LJ | 1 |
| Anderson, J; Shamsuddin, M; Smith, LJ | 1 |
| Nguyên, P; Petitfrère, E; Potron, G | 1 |
| Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Blom, M; Knol, EF; Mul, FP; Roos, D; Tool, AT; Verhoeven, AJ | 1 |
| Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Leonardi, G | 1 |
| Fairbairn, SM; Hellewell, PG; Norman, KE; Rossi, AG; Teixeira, MM; Williams, TJ | 1 |
| Cowley, FS; Elstad, MR; McIntyre, TM; Parker, CJ; Prescott, SM; Wilcox, LA; Zimmerman, GA | 1 |
| Argenbright, LW; Norman, KE; Rossi, AG; Williams, TJ | 1 |
| Berger, F; Borchard, U; Hafner, D; Weis, T | 1 |
| Foster, M; Gueremy, T; Turner, NC; Wood, LJ | 1 |
| Koenderman, L; Kok, PT; Lammers, JW; Raaijmakers, JA; van der Bruggen, T | 1 |
| Ahluwalia, A; Perretti, M | 1 |
| Borgeat, P; Braquet, P; Palmantier, R; Sanchez, A; Surette, ME | 1 |
| Biancone, L; Camussi, G; Da Col, R; Libertucci, D; Scappaticci, E; Silvestro, L | 1 |
| Blom, M; Koenderman, L; Kok, PT; Lammers, JW; Raaijmakers, JA; van der Bruggen, T; Verhoeven, AJ | 1 |
| Bowen, JG; Meats, JE; Steele, L | 1 |
| Lobb, RR; Nourshargh, S; Weg, VB; Williams, TJ | 1 |
| Azzari, C; Baldi, E; Carloni, V; Gentilini, P; Gresele, P; Laffi, G; Marra, F; Rossi, ME | 1 |
| Bourdon, V; Damas, J; Remacle-Volon, G | 1 |
| Hayashi, M; Imai, Y; Naraba, H; Oh-ishi, S | 1 |
| Kessels, RG; Koenderman, L; Kok, PT; Lammers, JW; Raaijmakers, JA; van der Bruggen, T; Verhoeven, AJ | 1 |
| Norman, KE; Nourshargh, S; Pons, F; Rossi, AG; Williams, TJ | 1 |
| Imai, Y; Kudo, I; Nakagawa, Y; Naraba, H; Oh-ishi, S | 1 |
| Tool, AT; Verhoeven, AJ | 1 |
| Chapman, MJ; Dentan, C; Lesnik, P; Ninio, E | 1 |
| Clough, J; Cypcar, D; Kaplan, M; Lemanske, RF; Nagata, M; Sedgwick, J; Sorkness, R | 1 |
| Hellewell, PG; Macari, DM; Teixeira, MM | 1 |
| Matsumoto, H; Naraba, H; Oh-ishi, S; Ueno, A | 1 |
| Calignano, A; Cozzolino, A; Mancuso, F; Metafora, S; Porta, R | 1 |
| Gercken, G; Kleuser, B; Meister, A; Sternfeld, L | 1 |
| Anderson, R; Feldman, C; Theron, AJ | 1 |
| Buurman, WA; Dentener, MA; Francot, GJ; Hiemstra, PS; Tool, AT; Vandenabeele, P; Verhoeven, AJ | 1 |
| Byrum, RS; Goulet, JL; Griffiths, RJ; Koller, BH | 1 |
| Hellewell, PG; Teixeira, MM | 1 |
| Antonopoulou, S; Argyropoulos, D; Avramopoulou, V; Demopoulos, CA; Froussios, C | 1 |
| Oh-ishi, S | 1 |
| Coffer, PJ; Geijsen, N; Koenderman, L; Lammers, JW; M'rabet, L; Maikoe, T; Raaijmakers, JA; Schweizer, RC | 1 |
| Kanters, D; Koenderman, L; Lammers, JW; Raaijmakers, JA; Tool, AT; van der Bruggen, T; Verhoeven, AJ | 1 |
| Hellewell, PG; Jeffery, PK; Miotla, JM | 1 |
| Huh, H; Kim, HK; Lee, HK | 1 |
| Akard, LP; Cui, Y; English, D; Garcia, JG; Siddiqui, RA | 1 |
| Huang, TF; Hung, WC; Ko, WC; Lee, LW; Lin, CH; Peng, HC; Sheu, JR; Su, CH; Yen, MH | 1 |
| Aslander, MM; Brinkman, L; Grutters, JC; Koenderman, L; Lammers, JW; van den Bosch, JM | 1 |
| Evanson, OA; McClenahan, DJ; Walcheck, BK; Weiss, DJ | 1 |
| Bock, CB; Haribabu, B; Sellars, DD; Snyderman, R; Steeber, DA; Verghese, MW | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Kolaczkowska, E; Plytycz, B; Seljelid, R; Shahzidi, S; van Rooijen, N | 1 |
| Bissonnette, SA; Brown, GE; Elia, AE; Stewart, MQ; Wilker, E; Yaffe, MB | 1 |
| Kusters, A; Naber, T; Roos, D; Tool, A; van Emst-de Vries, SE; Wanten, G; Willems, P | 1 |
| Dennis, EA; Kessen, UA; Provins, JW; Schaloske, RH | 1 |
| Chatterjee, BE; Flower, RJ; Nourshargh, S; Perretti, M; Rosignoli, G; Yona, S; Young, RE | 1 |
| Kato, H; Kojima, F; Matsushita, M; Naraba, H; Narumiya, S; Oh-Ishi, S; Sugimoto, Y; Ueno, A; Ushikubi, F; Yuhki, K | 1 |
| Hu, Y; Liu, J; Liu, Y; Ma, S; Qu, J; Si, Y; Xu, S; Yu, S | 1 |
| Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
| Ebina, K; Sato, A | 1 |
| Cai, SQ; Chen, HB; Shang, MY; Wang, RF; Wang, TM | 1 |
| Corris, PA; De Soyza, A; Gertig, H; Hester, KL; Macfarlane, JG; Ruchaud-Sparagano, MH; Simpson, AJ | 1 |
| Alonso, S; Crespo, MS; Fernández, N; Frade, JG; Márquez, S; Montero, O; Rodríguez, M | 1 |
1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Analysis of chemical mediators involved in acute inflammatory reaction with the rat pleurisy model].
Topics: Animals; Arachidonic Acid; Capillary Permeability; Carrageenan; Cell Movement; Chemokines; Complement System Proteins; Disease Models, Animal; Eicosanoids; Histamine; Inflammation; Kallikrein-Kinin System; Male; Neutrophils; Platelet Activating Factor; Pleurisy; Rats; Zymosan | 1997 |
1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Asthma therapy modulates priming-associated blood eosinophil responsiveness in allergic asthmatics.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Allergens; Asthma; Beclomethasone; Blood Proteins; Bronchial Provocation Tests; Double-Blind Method; Drug Therapy, Combination; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Male; Platelet Activating Factor; Reactive Oxygen Species; Respiratory Burst; Ribonucleases; Salmeterol Xinafoate; Treatment Outcome; Zymosan | 1999 |
142 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Different preparations of zymosan induce glycogenolysis independently in the perfused rat liver. Involvement of mannose receptors, peptide-leukotrienes and prostaglandins.
Topics: Animals; Chromones; Glycogen; Hot Temperature; Ibuprofen; Isoproterenol; Liver; Male; Mannans; Masoprocol; Opsonin Proteins; Platelet Activating Factor; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Immunologic; Receptors, Leukotriene; Solubility; Zymosan | 1992 |
Differential effects of platelet-activating factor on superoxide anion production in human eosinophils and neutrophils.
Topics: Eosinophils; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
The role of complement, platelet-activating factor and leukotriene B4 in a reversed passive Arthus reaction.
Topics: Animals; Arthus Reaction; Azepines; Complement System Proteins; Edema; Isoquinolines; Leukotriene B4; Platelet Activating Factor; Rabbits; Radioimmunoassay; Receptors, Complement; Tetrazoles; Triazoles; Zymosan | 1992 |
Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules.
Topics: Cytoplasmic Granules; Enzyme-Linked Immunosorbent Assay; Gelatinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactoferrin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pepsin A; Platelet Activating Factor; Protein Binding; Subcellular Fractions; Vitamin B 12; Zymosan | 1992 |
Platelet activating factor stimulates and primes the liver, Kupffer cells and neutrophils to release superoxide anion.
Topics: Animals; Anions; Free Radicals; Ibuprofen; In Vitro Techniques; Kupffer Cells; Lipopolysaccharides; Liver; Male; Neutrophils; Peroxidase; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Zymosan | 1992 |
A new, one-step assay on whole cell suspensions for peroxidase secretion by human neutrophils and eosinophils.
Topics: Calcimycin; Cell Separation; Eosinophil Peroxidase; Eosinophils; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Platelet Activating Factor; Reference Values; Spectrophotometry; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Priming of human eosinophils by platelet-activating factor enhances the number of cells able to bind and respond to opsonized particles.
Topics: Adenosine Triphosphate; Complement C3b; Energy Metabolism; Eosinophils; Humans; In Vitro Techniques; Phagocytosis; Platelet Activating Factor; Respiratory Burst; Temperature; Zymosan | 1992 |
Ligand dependent release of activated neutrophil collagenase--a role for surface bound IgG in the degradation of articular collagens.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Collagenases; Humans; Immunoglobulin G; Ligands; Matrix Metalloproteinase 8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Antigen, B-Cell; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Release of platelet-activating factor is important for the respiratory burst induced in human eosinophils by opsonized particles.
Topics: Azepines; Eosinophils; Humans; In Vitro Techniques; Kinetics; Oxygen Consumption; Phospholipases A; Platelet Activating Factor; Triazoles; Zymosan | 1992 |
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan | 1992 |
The accumulation of 111In-eosinophils induced by inflammatory mediators, in vivo.
Topics: Albumins; Animals; Cell Movement; Complement C5a; Dermatitis, Atopic; Eosinophils; Female; Guinea Pigs; Indium Radioisotopes; Leukotriene B4; Platelet Activating Factor; Recombinant Proteins; Skin; Zymosan | 1991 |
Receptor-mediated activation of arachidonic acid release in mouse peritoneal macrophages is linked to extracellular calcium influx.
Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Egtazic Acid; Kinetics; Macrophages; Mice; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Receptors, Cell Surface; Verapamil; Zymosan | 1991 |
Neutrophil chemiluminescence and superoxide production in patients with rheumatoid arthritis: the effect of zymosan, phorbol myristate acetate and platelet-activating factor.
Topics: Arthritis, Rheumatoid; Humans; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Comparative study of the effect of CV-6209, a specific PAF-antagonist, on rat paw edema caused by different phlogogen agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Carrageenan; Dextrans; Edema; Histamine Antagonists; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Serotonin Antagonists; Zymosan | 1990 |
Site of anti-inflammatory action of dexamethasone in rabbit skin.
Topics: Animals; Bradykinin; Dactinomycin; Dermatitis, Contact; Dexamethasone; Dinoprostone; Female; Histamine; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Biosynthesis; Rabbits; RNA; Skin; Zymosan | 1991 |
Cell adhesion by membrane-bound paf-acether.
Topics: Animals; Azepines; Calcimycin; Cell Adhesion; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Triazoles; Zymosan | 1991 |
Key role of complement activation and platelet-activating factor in exudate formation in zymosan-induced rat pleurisy.
Topics: Animals; Complement Activation; Complement System Proteins; Elapid Venoms; Leukocytes; Male; Platelet Activating Factor; Pleural Effusion; Pleurisy; Rats; Rats, Inbred BN; Rats, Inbred Strains; Time Factors; Zymosan | 1991 |
Involvement of platelet-activating factor in zymosan-induced rat pleurisy.
Topics: Animals; Cyproheptadine; Eosinophils; Inflammation; Leukocytes; Male; Mast Cells; Neutrophils; Platelet Activating Factor; Pleurisy; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Zymosan | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Time-dependent synergistic interactions between the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP) and mediators of inflammation.
Topics: Animals; Calcitonin Gene-Related Peptide; Complement C5a; Drug Synergism; Epoprostenol; In Vitro Techniques; Indium Radioisotopes; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Time Factors; Zymosan | 1991 |
Ether lysophospholipid-induced production of platelet-activating factor in human polymorphonuclear leukocytes.
Topics: Acetates; Acetyl Coenzyme A; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Zymosan | 1990 |
Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Epoprostenol; Guinea Pigs; Macrophage Activation; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Zymosan | 1990 |
Comparison of the generation of platelet-activating factor and leukotriene C4 in human eosinophils stimulated by unopsonized zymosan and by the calcium ionophore A23187: the effects of nedocromil sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eosinophils; Humans; Nedocromil; Opsonin Proteins; Platelet Activating Factor; Platelet Aggregation; Quinolones; SRS-A; Stimulation, Chemical; Time Factors; Zymosan | 1990 |
Ligand-dependent release of active neutrophil collagenase.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Humans; Immunoglobulin G; In Vitro Techniques; Ligands; Microbial Collagenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Zymosan | 1990 |
Antiallergic and anti-inflammatory action of tioxamast in rats. II. Anti-inflammatory action in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Histamine Antagonists; Male; Oxamic Acid; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Zymosan | 1990 |
Priming of the respiratory burst in human eosinophils is accompanied by changes in signal transduction.
Topics: Alkaloids; Calcium; Cells, Cultured; Diglycerides; Eosinophils; Humans; Oxygen Consumption; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Staurosporine; Zymosan | 1990 |
Cooperation between platelets and neutrophils for paf-acether (platelet-activating factor) formation.
Topics: Animals; Blood Platelets; Cell Communication; Female; Humans; Inflammation; L-Lactate Dehydrogenase; Male; Muramidase; Neutrophils; Platelet Activating Factor; Rabbits; Thrombin; Zymosan | 1990 |
Ethanol inhibits zymosan-stimulated and enhances nonstimulated platelet-activating factor production in a clonal macrophage cell line.
Topics: Animals; Cell Line; Ethanol; Macrophages; Phagocytosis; Platelet Activating Factor; Zymosan | 1990 |
Chemotactic competence of neutrophils from neonatal calves. Functional comparison with neutrophils from adult cattle.
Topics: Aging; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cattle; Cell Migration Inhibition; Chemotaxis, Leukocyte; Complement C5a; Hematologic Tests; Lipopolysaccharides; Neutrophils; Platelet Activating Factor; Vitamin D-Binding Protein; Zymosan | 1990 |
Effects of in vivo 'priming' on endotoxin-induced hypotension and tissue injury. The role of PAF and tumor necrosis factor.
Topics: Animals; BCG Vaccine; Endotoxins; Gastrointestinal Diseases; Hypotension; Lipopolysaccharides; Platelet Activating Factor; Quinolinium Compounds; Rats; Rats, Inbred Strains; Shock, Septic; Tumor Necrosis Factor-alpha; Zymosan | 1990 |
In vitro aggregation of bovine neonatal neutrophils. A comparative study with adult cattle.
Topics: Aging; Animals; Animals, Newborn; Cattle; Cell Aggregation; Neutrophils; Platelet Activating Factor; Zymosan | 1990 |
Augmented production of platelet-activating factor in human polymorphonuclear leukocytes by ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Calcimycin; Dimethyl Sulfoxide; Humans; Hydroxybutyrates; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Calcium is necessary but not sufficient for the platelet-activating factor release in human neutrophils stimulated by physiological stimuli. Role of G-proteins.
Topics: Colony-Stimulating Factors; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Second Messenger Systems; Zymosan | 1989 |
Biosynthesis of paf-acether. Paf-acether but not leukotriene C4 production is impaired in cultured macrophages.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Platelet Activating Factor; SRS-A; Zymosan | 1989 |
Inhibitory effects of nedocromil sodium on the in vitro induced migration and leukotriene formation of human granulocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Leukotriene B4; Leukotrienes; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; SRS-A; Zymosan | 1989 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Inhibition of platelet-activating factor- and zymosan-activated serum-induced chemotaxis of human neutrophils by nedocromil sodium, BN 52021 and sodium cromoglycate.
Topics: Calcium; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; Zymosan | 1989 |
Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism.
Topics: Arachidonic Acids; Humans; Leukotriene B4; Leukotrienes; Models, Biological; Phagocytes; Phagocytosis; Platelet Activating Factor; Thromboxane B2; Zymosan | 1989 |
Platelet-activating factor (PAF) acts as an intercellular messenger in the changes of cytosolic free Ca2+ in human neutrophils induced by opsonized particles.
Topics: Azepines; Calcium; Cytosol; Humans; In Vitro Techniques; Neutrophils; Phagocytosis; Platelet Activating Factor; Signal Transduction; Triazines; Triazoles; Zymosan | 1989 |
Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage.
Topics: Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Leukotriene B4; Macrophages; Masoprocol; Methionine; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Zymosan | 1987 |
Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
Topics: Animals; Aspirin; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Endotoxins; Female; Furans; Hypertension, Pulmonary; Hypoxia; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Thromboxanes; Zymosan | 1987 |
An endogenous source of the superoxide anion in the central nervous system.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Concanavalin A; Kinetics; Microscopy, Electron; Neuroglia; Platelet Activating Factor; Potassium Chloride; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Mediators of inflammation and antagonism of experimental pleurisy in the rat by fenspiride.
Topics: Animals; Female; Guinea Pigs; Inflammation; Male; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Spiro Compounds; Zymosan | 1988 |
Pharmacological modulation of Paf-induced rat pleurisy and its role in inflammation by zymosan.
Topics: Animals; Azepines; Carrageenan; Leukocyte Count; Male; Platelet Activating Factor; Pleurisy; Pyridines; Rats; Rats, Inbred Strains; Thiazoles; Triazines; Triazoles; Zymosan | 1989 |
Exclusive leukotriene C4 synthesis by purified human eosinophils induced by opsonized zymosan.
Topics: Calcimycin; Eosinophils; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Platelet Activating Factor; SRS-A; Zymosan | 1985 |
Modulation of neutrophil oxidative responses to soluble stimuli by platelet-activating factor.
Topics: Adult; Diglycerides; Fatty Acids; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Oxygen Consumption; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.
Topics: Arthritis, Rheumatoid; Bacterial Infections; C-Reactive Protein; Calcimycin; Cytochalasin B; Free Radicals; Humans; Hydrogen Peroxide; Leukocyte Count; Neutrophils; Oxygen; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Effect of group B streptococcal type-specific antigen on polymorphonuclear leukocyte function and polymorphonuclear leukocyte-endothelial cell interaction.
Topics: Antigens, Bacterial; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Complement System Proteins; Endothelium; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Streptococcus agalactiae; Zymosan | 1987 |
Influence of lysophospholipids and PAF on the oxidative burst of PMNL.
Topics: Acetophenones; Animals; Complement C5; Complement C5a; Female; Guinea Pigs; In Vitro Techniques; Luminescent Measurements; Lysophosphatidylcholines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
[Effect of corticosteroids, quinacrine and L-652, 731 on experimental aggregation of polymorphonuclear leukocytes induced by complement and platelet activating factor (PAF)].
Topics: Agranulocytosis; Animals; Cell Aggregation; Complement System Proteins; Furans; Methylprednisolone; Methylprednisolone Hemisuccinate; Neutropenia; Platelet Activating Factor; Quinacrine; Rabbits; Zymosan | 1988 |
Arachidonic acid turnover in response to lipopolysaccharide and opsonized zymosan in human monocyte-derived macrophages.
Topics: Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Fatty Acids; Humans; Lipopolysaccharides; Macrophages; Opsonin Proteins; Phosphatidylcholines; Phospholipids; Platelet Activating Factor; Zymosan | 1986 |
Platelet-activating factor induces leukotriene C4 synthesis by purified human eosinophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Drug Synergism; Eosinophils; Humans; Platelet Activating Factor; Radioimmunoassay; SRS-A; Time Factors; Zymosan | 1987 |
Effect of selected antiinflammatory agents and other drugs on zymosan, arachidonic acid, PAF and carrageenan induced paw edema in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Carrageenan; Drug Evaluation, Preclinical; Edema; Female; Mice; Platelet Activating Factor; Zymosan | 1987 |
Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes.
Topics: Calcimycin; Cell Adhesion; Cell Differentiation; Humans; Macrophage Activation; Monocytes; Opsonin Proteins; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Age-dependent differential development of leukotactic and vasoactive responsiveness to acute inflammatory mediators.
Topics: Aging; Animals; Blood; Bradykinin; Capillary Permeability; Chemotaxis, Leukocyte; Dinoprostone; Female; Histamine; Inflammation; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandins E; Rabbits; Zymosan | 1986 |
Platelet-activating factor (PAF-acether) induced leukotriene C4 formation and luminol dependent chemiluminescence by human eosinophils.
Topics: Eosinophils; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyridazines; SRS-A; Zymosan | 1986 |
Pharmacological analysis of guinea-pig macrophage chemiluminescence responses to platelet activating factor and opsonized zymosan.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Kinetics; Luminescent Measurements; Macrophage Activation; Macrophages; Male; Methylation; Opsonin Proteins; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Propionibacterium acnes; Zymosan | 1986 |
Hydrocortisone and 'macrocortin' inhibit the zymosan-induced release of lyso-PAF from rat peritoneal leucocytes.
Topics: Acetylation; Animals; Ascitic Fluid; Glycoproteins; Hydrocortisone; Intracellular Signaling Peptides and Proteins; Leukocytes; Phospholipases; Platelet Activating Factor; Rats; Sulfhydryl Reagents; Zymosan | 1985 |
Permeability-increasing ability of PAF-acether in rat skin.
Topics: Animals; Capillary Permeability; Cell Membrane Permeability; Dose-Response Relationship, Drug; Histamine; Male; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Zymosan | 1985 |
Desensitization of acute inflammatory lesions to chemotaxins and endotoxin.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
Lipid-mediator synthesis in peritoneal macrophages from mice injected with immunostimulants.
Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Autacoids; Female; In Vitro Techniques; Lipids; Macrophages; Mice; Platelet Activating Factor; Prostaglandins; Zymosan | 1983 |
The role of calcium ions in the process of acetyltransferase activation during the formation of platelet-activating factor (PAF-acether).
Topics: Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Animals; Biological Transport; Calcimycin; Calcium; Enzyme Activation; Gallic Acid; In Vitro Techniques; Macrophages; Platelet Activating Factor; Rats; Rats, Inbred Strains; Zymosan | 1984 |
Platelet-activating factor (PAF-acether) and macrophages. II. Phagocytosis-associated release of PAF-acether from rat peritoneal macrophages.
Topics: Animals; Antigen-Antibody Complex; Ascitic Fluid; Bordetella pertussis; Colchicine; Cytochalasin B; Endocytosis; Erythrocytes; Female; Lysophosphatidylcholines; Macrophages; Male; Microspheres; Phagocytosis; Platelet Activating Factor; Rats; Zymosan | 1981 |
Modulatory role of cyclic AMP in the release of platelet-activating factor from human polymorphonuclear leucocytes.
Topics: Blood Coagulation Factors; Blood Platelets; Cyclic AMP; Cyclic GMP; Epinephrine; Glucuronidase; Humans; Isoproterenol; Lysophosphatidylcholines; Phosphodiesterase Inhibitors; Pilocarpine; Platelet Activating Factor; Platelet Aggregation; Zymosan | 1982 |
Differential activation of phosphatidylinositol deacylation and a pathway via diphosphoinositide in macrophages responding to zymosan and ionophore A23187.
Topics: Animals; Calcimycin; Calcium; Kinetics; Macrophages; Mice; Monensin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Platelet Activating Factor; Zymosan | 1984 |
Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine by rat alveolar macrophages. Phospholipase A2 and acetyltransferase activities during phagocytosis and ionophore stim
Topics: Acetyltransferases; Animals; Anti-Bacterial Agents; Calcimycin; Kinetics; Lung; Macrophages; Phagocytosis; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Rats; Zymosan | 1983 |
Effect of platelet-activating factor and serum-treated zymosan on prostaglandin E2 synthesis, arachidonic acid release, and contraction of cultured rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Glomerular Mesangium; Phagocytosis; Platelet Activating Factor; Prostaglandins E; Rats; Zymosan | 1984 |
Structure elucidation of platelet activating factor derived from human neutrophils.
Topics: Adult; Calcimycin; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Neutrophils; Platelet Activating Factor; Zymosan | 1984 |
1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine. A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Humans; Models, Biological; Neutrophils; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Time Factors; Zymosan | 1984 |
Kinetics of neutrophil accumulation in acute inflammatory lesions induced by chemotaxins and chemotaxinigens.
Topics: Acute Disease; Animals; Caseins; Chemotactic Factors; Concanavalin A; Dose-Response Relationship, Immunologic; Endotoxins; Female; Inflammation; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Zymosan | 1984 |
Paf-acether generates chemiluminescence in human neutrophils in the absence of cytochalasin B.
Topics: Cytochalasin B; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Luminol; Neutrophils; Opsonin Proteins; Phagocytosis; Phospholipids; Platelet Activating Factor; Zymosan | 1984 |
Biosynthesis of platelet-activating factor (PAF-acether). IV. Impairment of acetyl-transferase activity in thioglycollate-elicited mouse macrophages.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Calcimycin; Female; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Thioglycolates; Zymosan | 1982 |
Effect of platelet activating factor on leukocytes. II. Enhancement of eosinophil chemotactic factor and beta-glucuronidase release.
Topics: Calcimycin; Chemotactic Factors; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement System Proteins; Drug Synergism; Eosinophils; Glucuronidase; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Zymosan | 1982 |
Platelet serotonin release by human polymorphonuclear leucocytes stimulated by cotton dust bacteria.
Topics: Adult; Animals; Blood Platelets; Cells, Cultured; Dose-Response Relationship, Immunologic; Enterobacter; Enterobacteriaceae; Gossypium; Humans; Neutrophils; Platelet Activating Factor; Rabbits; Serotonin; Time Factors; Zymosan | 1983 |
Release of PAF by human polymorphonuclear leucocytes stimulated by immune complexes bound to Sepharose particles and human erythrocytes.
Topics: Animals; Antigen-Antibody Complex; Erythrocytes; Humans; Indomethacin; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Zymosan | 1983 |
Biosynthesis of platelet-activating factor (PAF)acether). III. Formation of PAF-acether from synthetic substrates by stimulated murine macrophages.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Ascitic Fluid; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Malonyl Coenzyme A; Mice; Palmitoyl Coenzyme A; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Zymosan | 1982 |
Inhibition of phospholipid methyltransferase during zymosan induced secretion of platelet-activating factor in human polymorphonuclear leukocytes.
Topics: Glucuronidase; Humans; In Vitro Techniques; Lysophosphatidylcholines; Methyltransferases; Neutrophils; Phagocytosis; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Platelet Activating Factor; Zymosan | 1981 |
Zymosan-induced IL-8 release from human neutrophils involves activation via the CD11b/CD18 receptor and endogenous platelet-activating factor as an autocrine modulator.
Topics: Antibodies, Monoclonal; Calcimycin; CD18 Antigens; Humans; Integrins; Interleukin 1 Receptor Antagonist Protein; Interleukin-8; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sialoglycoproteins; Tetrazoles; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Kinetics, dose response, tachyphylaxis and cross-tachyphylaxis of vascular leakage induced by endotoxin, zymosan-activated plasma and platelet-activating factor in the horse.
Topics: Animals; Capillary Permeability; Cell Movement; Complement C5a; Dermatitis, Contact; Dose-Response Relationship, Drug; Endothelium, Vascular; Endotoxins; Escherichia coli; Female; Horse Diseases; Horses; Iodine Radioisotopes; Kinetics; Male; Platelet Activating Factor; Serum Albumin; Tachyphylaxis; Zymosan | 1995 |
E-type prostaglandins enhance local oedema formation and neutrophil accumulation but suppress eosinophil accumulation in guinea-pig skin.
Topics: Alprostadil; Animals; Dinoprostone; Edema; Eosinophils; Guinea Pigs; Iloprost; In Vitro Techniques; Indium Radioisotopes; Isoproterenol; Male; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Prostaglandins E; Skin; Zymosan | 1993 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Superoxide generation by guinea-pig peritoneal macrophages is inhibited by rolipram, staurosporine and mepacrine in an agonist-dependent manner.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Macrophages, Peritoneal; Male; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Platelet Activating Factor; Protein Kinase C; Pyrrolidinones; Quinacrine; Respiratory Burst; Rolipram; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Differential regulation of leukotriene and platelet-activating factor synthesis in rat alveolar macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Leukotrienes; Macrophages, Alveolar; Male; Phospholipases; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Zymosan | 1995 |
Mechanisms of the platelet aggregation induced by activated neutrophils and inhibitory effect of specific PAF receptor antagonists.
Topics: Culture Media, Conditioned; Cyclic AMP; Humans; Neutrophils; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Zymosan | 1995 |
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan | 1994 |
Eosinophils isolated with two different methods show different characteristics of activation.
Topics: Antigens, CD; Cell Separation; Cells, Cultured; Chemotaxis, Leukocyte; Eosinophils; Flow Cytometry; Humans; Immunomagnetic Separation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Receptors, IgG; Respiratory Burst; Zymosan | 1995 |
Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cantharidin; Croton Oil; Dermatitis; Dose-Response Relationship, Drug; Ear, External; Edema; Male; Mice; Papaverine; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Zymosan | 1994 |
Studies on the mechanisms involved in the inflammatory response in a reversed passive Arthus reaction in guinea-pig skin: contribution of neutrophils and endogenous mediators.
Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; CD18 Antigens; Edema; Guinea Pigs; Histamine H1 Antagonists; Indium Radioisotopes; Inflammation; Inflammation Mediators; Leukocytes; Lipoxygenase Inhibitors; Neutrophils; Nitric Oxide; Platelet Activating Factor; Rabbits; Skin; Zymosan | 1994 |
CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes.
Topics: Antigens, CD; CD18 Antigens; Humans; In Vitro Techniques; Macrophage-1 Antigen; Monocytes; Opsonin Proteins; Platelet Activating Factor; Receptors, Immunologic; Zymosan | 1994 |
Role of adhesion glycoproteins CD18 and intercellular adhesion molecule-1 in complement-mediated reactions of rabbit skin.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Arthus Reaction; Bradykinin; CD18 Antigens; Cell Adhesion Molecules; Dinoprostone; Dogs; Edema; Hemorrhage; Humans; Intercellular Adhesion Molecule-1; Mice; Platelet Activating Factor; Rabbits; Receptors, Leukocyte-Adhesion; Skin; Zymosan | 1994 |
Activation of a potassium outward current by zymosan and opsonized zymosan in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Cell Membrane; In Vitro Techniques; Macrophages; Male; Membrane Potentials; Mice; Opsonin Proteins; Patch-Clamp Techniques; Platelet Activating Factor; Potassium Channels; Receptors, Fc; Zymosan | 1994 |
Effects of PAF, FMLP and opsonized zymosan on the release of ECP, elastase and superoxide from human granulocytes.
Topics: Blood Proteins; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophil Granule Proteins; Granulocytes; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Platelet Activating Factor; Ribonucleases; Superoxides; Zymosan | 1994 |
Cooperation between Fc gamma receptor II and complement receptor type 3 during activation of platelet-activating factor release by cytokine-primed human eosinophils.
Topics: Cytokines; Eosinophils; Flow Cytometry; Humans; Macrophage-1 Antigen; Platelet Activating Factor; Receptors, IgG; Respiratory Burst; Zymosan | 1994 |
Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood; Dinoprostone; Edema; Male; Mice; Misoprostol; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, Prostaglandin E; Skin; Zymosan | 1994 |
Granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 greatly enhance the interaction of human eosinophils with opsonized particles by changing the affinity of complement receptor type 3.
Topics: Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-5; Macrophage-1 Antigen; Phagocytosis; Platelet Activating Factor; Quinacrine; Zymosan | 1994 |
Priming for the synthesis of 5-lipoxygenase products in human blood ex vivo by human granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha.
Topics: Arachidonate 5-Lipoxygenase; Calcimycin; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Development of a high-performance liquid chromatographic-mass spectrometric technique, with an ionspray interface, for the determination of platelet-activating factor (PAF) and lyso-PAF in biological samples.
Topics: Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Neutrophils; Platelet Activating Factor; Zymosan | 1993 |
Transient exposure of human eosinophils to the protein kinase C inhibitors CGP39-360, CGP41-251, and CGP44-800 leads to priming of the respiratory burst induced by opsonized particles.
Topics: Alkaloids; Calcium; Enzyme Inhibitors; Eosinophils; Humans; Opsonin Proteins; Organic Chemicals; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Identification of phospholipase D (PLD) activity in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, Thin Layer; Glycerophospholipids; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.
Topics: Animals; Antibodies, Monoclonal; Edema; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Receptors, Very Late Antigen; Zymosan | 1993 |
Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in cirrhosis.
Topics: Adult; Aged; Arachidonic Acid; Calcimycin; Female; Humans; Leukotriene B4; Liver Cirrhosis; Male; Mass Spectrometry; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1993 |
Platelet-activating factor and the vascular effects of zymosan in rats.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Female; Hematocrit; Hemodynamics; Iodine Radioisotopes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Triazoles; Zymosan | 1993 |
Enhanced production of platelet-activating factor in stimulated rat leukocytes caused by the blockade of lysophospholipid acylation.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Animals; Blood Platelets; Humans; In Vitro Techniques; Leukocytes; Lysophospholipids; Macrophages; Male; Neutrophils; Platelet Activating Factor; Rabbits; Rats; Rats, Sprague-Dawley; Thimerosal; Triazenes; Vasodilator Agents; Zymosan | 1993 |
Cytokine priming of the respiratory burst in human eosinophils is Ca2+ independent and accompanied by induction of tyrosine kinase activity.
Topics: Calcium; Dose-Response Relationship, Drug; Enzyme Induction; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interleukin-3; Interleukin-5; Ionomycin; Kinetics; Molecular Weight; Oxygen Consumption; Phosphoproteins; Platelet Activating Factor; Protein-Tyrosine Kinases; Recombinant Proteins; Zymosan | 1993 |
Role of platelet-activating factor (PAF) in platelet accumulation in rabbit skin: effect of the novel long-acting PAF antagonist, UK-74,505.
Topics: Animals; Arthus Reaction; Blood Platelets; Calcium; Dihydropyridines; Edema; Fura-2; Imidazoles; In Vitro Techniques; Indium Radioisotopes; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin; Skin; Zymosan | 1993 |
Activation of phospholipase A2 and acylation of lysophospholipids: the major regulators for platelet activating factor production in rat neutrophils.
Topics: Acylation; Animals; Antibodies, Monoclonal; Arachidonic Acid; Enzyme Activation; Lysophospholipids; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thimerosal; Triazenes; Zymosan | 1995 |
Inhibition of the production of platelet activating factor and of leukotriene B4 in activated neutrophils by nimesulide due to an elevation of intracellular cyclic adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Sulfonamides; Zymosan | 1995 |
Phagocytic activation induces formation of platelet-activating factor in human monocyte-derived macrophages and in macrophage-derived foam cells. Relevance to the inflammatory reaction in atherogenesis.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Arteriosclerosis; Cells, Cultured; Foam Cells; Humans; Inflammation; Lipase; Macrophage Activation; Macrophages; Monocytes; Opsonin Proteins; Phagocytosis; Phospholipases A; Platelet Activating Factor; Zymosan | 1996 |
Rat eosinophils: isolation and characterization of superoxide production.
Topics: Animals; Calcimycin; Cell Separation; Cytochalasin B; Eosinophils; Humans; In Vitro Techniques; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Priming of eosinophil recruitment in vivo by LPS pretreatment.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; CD18 Antigens; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cycloheximide; Drug Synergism; Edema; Eosinophilia; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Protein Synthesis Inhibitors; Pyrans; Quinolones; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Sialoglycoproteins; Skin; Triazoles; Zymosan | 1996 |
Inhibitory effect of arachidonic acid on platelet-activating factor production in rat neutrophils.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indomethacin; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazenes; Zymosan | 1996 |
Inhibition of zymosan-induced air-pouch inflammation by rat seminal vesicle protein and by its spermidine derivative.
Topics: Animals; Dinoprostone; Inflammation; Male; Mice; Platelet Activating Factor; Prostatic Secretory Proteins; Proteins; Rats; Seminal Plasma Proteins; Spermidine; Zymosan | 1996 |
Measurement of phospholipase A2 and 1-alkylglycerophosphocholine acetyltransferase activities in stimulated alveolar macrophages by HPLC analysis of NBD-labeled ether lipids.
Topics: 4-Chloro-7-nitrobenzofurazan; Acetyltransferases; Animals; Cattle; Chromatography, High Pressure Liquid; Fluorescent Dyes; Indicators and Reagents; Ionophores; Lysosomes; Macrophages, Alveolar; Phagocytosis; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Platelet Activating Factor; Silicon Dioxide; Vanadium Compounds; Zymosan | 1996 |
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Topics: Adult; Anti-Asthmatic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Azithromycin; Calcimycin; Cell Membrane; Clarithromycin; Erythromycin; Humans; Ionophores; Luminescent Measurements; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Roxithromycin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Bactericidal/permeability-increasing protein release in whole blood ex vivo: strong induction by lipopolysaccharide and tumor necrosis factor-alpha.
Topics: Antigens, CD; Antimicrobial Cationic Peptides; Blood Bactericidal Activity; Blood Proteins; Complement C5a; Humans; Interleukin-1; Interleukin-8; Kinetics; Leukocyte Elastase; Lipopolysaccharides; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1997 |
Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses.
Topics: 5-Lipoxygenase-Activating Proteins; Anaphylaxis; Animals; Arachidonic Acid; Carrier Proteins; DNA, Complementary; Edema; Eicosanoids; Hypersensitivity, Delayed; Immunoglobulin E; Inflammation; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Peritonitis; Peroxidase; Platelet Activating Factor; RNA, Messenger; Transcription, Genetic; Zymosan | 1997 |
Evidence that the eosinophil is a cellular target for the inhibitory action of salmeterol on eosinophil recruitment in vivo.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cell Aggregation; Depression, Chemical; Eosinophils; Guinea Pigs; Humans; Platelet Activating Factor; Salmeterol Xinafoate; Skin; Zymosan | 1997 |
Synthesis of a new phosphoglycolipid with biological activity towards platelets.
Topics: Animals; Anti-Asthmatic Agents; Blood Platelets; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diterpenes; Fibrinolytic Agents; Ginkgolides; Glucosides; Lactones; Mass Spectrometry; Phosphatidic Acids; Plants; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1997 |
Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function.
Topics: Androstadienes; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Cytokines; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Protein Kinases; Respiratory Burst; Signal Transduction; Wortmannin; Zymosan | 1998 |
Cytokine-induced protein tyrosine phosphorylation is essential for cytokine priming of human eosinophils.
Topics: Benzoquinones; Cytokines; Enzyme Inhibitors; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interleukin-3; Interleukin-5; Lactams, Macrocyclic; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Proteins; Quinones; Respiratory Burst; Rifabutin; Tyrosine; Zymosan | 1998 |
Platelet-activating factor plays a pivotal role in the induction of experimental lung injury.
Topics: Animals; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Elapid Venoms; Extravascular Lung Water; Female; Humans; Imidazoles; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Serum Albumin; Skin; Zymosan | 1998 |
PAF antagonistic activity of 2-hydroxy-3-methoxybenzoic acid glucose ester from Gentiana scabra.
Topics: Anaphylaxis; Animals; Benzoates; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Glucosides; Mice; Mice, Inbred ICR; Plants, Medicinal; Platelet Activating Factor; Rauwolfia | 1998 |
Chemotactic migration triggers IL-8 generation in neutrophilic leukocytes.
Topics: Animals; Caseins; Cattle; Cells, Cultured; Chemotaxis, Leukocyte; Complement C5a; Endothelium, Vascular; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Synthesis Inhibitors; RNA, Messenger; Zymosan | 1999 |
Triflavin potentiates the antiplatelet activity of platelet activating factor receptor antagonist on activated neutrophil-induced platelet aggregation.
Topics: Animals; Culture Media, Conditioned; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Fibrinolytic Agents; Ginkgolides; Lactones; Neutrophils; Peptides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Zymosan | 1999 |
Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils.
Topics: Calcium; CD18 Antigens; Cell Adhesion; Cell Survival; Diglycerides; Enzyme Activation; Eosinophils; Ethanol; Fibronectins; Humans; Macrophage-1 Antigen; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Propranolol; Protein Binding; Respiratory Burst; Tetradecanoylphorbol Acetate; Up-Regulation; Zymosan | 1999 |
Association among filamentous actin content, CD11b expression, and membrane deformability in stimulated and unstimulated bovine neutrophils.
Topics: Actins; Animals; Blood; Cattle; Cell Membrane; Exotoxins; Inflammation; Interleukin-8; Lipopolysaccharides; Macrophage-1 Antigen; Male; Mannheimia haemolytica; Neutrophils; Platelet Activating Factor; Tumor Necrosis Factor-alpha; Zymosan | 2000 |
Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis.
Topics: Anaphylaxis; Animals; Arachidonic Acid; Ear, External; Female; Gene Targeting; Inflammation Mediators; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Peritoneum; Platelet Activating Factor; Receptors, Leukotriene B4; Zymosan | 2000 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cysteine; Diterpenes; Eicosanoids; Enzyme Induction; Ginkgolides; Histamine Release; Indoles; Indomethacin; Isoenzymes; Lactones; Leukotriene C4; Leukotrienes; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Mast Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nitrobenzenes; Peritonitis; Phospholipid Ethers; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Quinolines; Sulfonamides; Thioglycolates; Zymosan | 2002 |
Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Ligands; Luminescent Measurements; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Pyridines; Reactive Oxygen Species; Swine; Tumor Necrosis Factor-alpha; Zymosan | 2004 |
Lipid effects on neutrophil calcium signaling induced by opsonized particles: platelet activating factor is only part of the story.
Topics: Calcium; Calcium Signaling; Emulsions; Fat Emulsions, Intravenous; Fish Oils; Humans; Neutrophil Activation; Neutrophils; Olive Oil; Plant Oils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Soybean Oil; Zymosan | 2004 |
Molecular characterization of the lipopolysaccharide/platelet activating factor- and zymosan-induced pathways leading to prostaglandin production in P388D1 macrophages.
Topics: Animals; Arachidonic Acids; Cell Line; Isoenzymes; Lipid Metabolism; Lipids; Lipopolysaccharides; Macrophages; Mice; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Signal Transduction; Zymosan | 2005 |
Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro.
Topics: Animals; Annexin A1; CD11b Antigen; Chemotaxis; Disease Models, Animal; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Muscle, Skeletal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Time Factors; Zymosan | 2005 |
Prostaglandin I2 plays a key role in zymosan-induced mouse pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Complement C3; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Elapid Venoms; Epoprostenol; Indomethacin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Zymosan | 2008 |
New vernocuminosides from the stem barks of Vernonia cumingiana Benth.
Topics: Animals; Anti-Inflammatory Agents; Drug Evaluation, Preclinical; Glucosides; Glucuronidase; Leukocytes; Plant Stems; Platelet Activating Factor; Rats; Steroids; Vernonia | 2009 |
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Models, Animal; Female; Humans; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lung; Male; Membrane Proteins; Mice; Pentanoic Acids; Platelet Activating Factor; Propionates; Rats; Substrate Specificity; Zymosan | 2010 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |
Endothelin-3 at low concentrations attenuates inflammatory responses via the endothelin B2 receptor.
Topics: Animals; Edema; Endothelin-3; Inflammation; Male; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Wistar; Receptor, Endothelin B; Zymosan | 2013 |
Alkyl and phenolic glycosides from Saussurea stella.
Topics: Animals; Anti-Inflammatory Agents; Coumaric Acids; Disaccharides; Female; Flavonoids; Furans; Glucosides; Glucuronidase; Glycosides; Hydroxybenzoates; Inflammation; Isoflavones; Lignans; Male; Molecular Structure; Neutrophils; Phytotherapy; Plant Extracts; Platelet Activating Factor; Quinic Acid; Rats, Wistar; Saussurea | 2013 |
Effect of granulocyte-macrophage colony-stimulating factor on neutrophil function in idiopathic bronchiectasis.
Topics: Aged; Bronchiectasis; Case-Control Studies; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Superoxides; Zymosan | 2013 |
Pharmacological inhibition of eicosanoids and platelet-activating factor signaling impairs zymosan-induced release of IL-23 by dendritic cells.
Topics: Dendritic Cells; Eicosanoids; Humans; Interleukin-23 Subunit p19; Platelet Activating Factor; Signal Transduction; Zymosan | 2016 |