Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and genistein

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with genistein in 20 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(genistein)
Trials
(genistein)
Recent Studies (post-2010) (genistein)
9,1561875527,4232042,311

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (75.00)18.2507
2000's5 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chao, W; Hanahan, DJ; Liu, H; Olson, MS1
Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB1
Dhar, A; Paul, AK; Shukla, SD1
Asmis, R; Dennis, EA; Glaser, KB1
Durán, WN; Kim, D1
Kellie, S; Murphy, CT; Westwick, J1
Bennett, SA; Birnboim, HC2
Baldi, E; Bonaccorsi, L; Forti, G; Gervasi, G; Krausz, C; Luconi, M1
Inagami, T; Inui, H; Kitami, Y; Kondo, T; Konishi, F1
Dillon, AM; Heath, MF1
Abebe, W; Agrawal, DK; Ali, N1
Ashour, MS; Fouda, SI; Molski, TF; Sha'afi, RI1
Bozza, PT; Cassara, J; Weller, PF; Yu, W1
Guo, ZG; Yi, FX; Zeng, S1
Boetticher, E; Jacobs, B; Leff, AR; Muñoz, NM; Sano, A; Sano, H; Subbaraman, R; Zhu, X1
Dent, G; Leff, AR; Magnussen, H; Munoz, NM; Rabe, KF; Rühlmann, E; Zhu, X1
Choi, IW; Choi, JH; Chung, WJ; Han, SJ; Han, SS; IM, SY; Jang, KY; Lee, DG; Lee, HB; Lee, HK; Park, KH1
Suenaga, A; Ueki, H1
Imai, H; Kitahara, J; Nakagawa, Y; Sakamoto, H; Tosaki, T1

Other Studies

20 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and genistein

ArticleYear
Protein tyrosine phosphorylation and regulation of the receptor for platelet-activating factor in rat Kupffer cells. Effect of sodium vanadate.
    The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3)

    Topics: Animals; Dinoprostone; Genistein; Isoflavones; Kinetics; Kupffer Cells; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sensitivity and Specificity; Stimulation, Chemical; Temperature; Time Factors; Vanadates

1992
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
    The Biochemical journal, 1992, Sep-01, Volume: 286 ( Pt 2)

    Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Platelet-activating factor stimulation of tyrosine kinase and its relationship to phospholipase C in rabbit platelets: studies with genistein and monoclonal antibody to phosphotyrosine.
    Molecular pharmacology, 1990, Volume: 37, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Blood Platelets; Blotting, Western; Flavonoids; Genistein; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tritium; Type C Phospholipases; Tyrosine

1990
PAF receptor mediated PGE2 production in LPS primed P388D1 macrophage-like cells.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Cyclooxygenase Inhibitors; Dactinomycin; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genistein; Isoflavones; Lipopolysaccharides; Macrophages; Mice; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Cells, Cultured

1991
Platelet-activating factor stimulates protein tyrosine kinase in hamster cheek pouch microcirculation.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Capillary Permeability; Catechols; Cheek; Cricetinae; Genistein; Isoflavones; Male; Mesocricetus; Microcirculation; Mouth Mucosa; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Platelet Activating Factor; Protein-Tyrosine Kinases; Tyrphostins

1995
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
    European journal of biochemistry, 1993, Sep-01, Volume: 216, Issue:2

    Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine

1993
Platelet activating factor induces transformation of human fibroblasts.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Alkaloids; Analysis of Variance; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Genistein; Growth Inhibitors; Humans; Indomethacin; Infant, Newborn; Isoflavones; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Skin; Staurosporine

1995
Stimulation of protein tyrosine phosphorylation by platelet-activating factor and progesterone in human spermatozoa.
    Molecular and cellular endocrinology, 1995, Feb-27, Volume: 108, Issue:1-2

    Topics: Acrosome; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Hydroquinones; Isoflavones; Male; Phosphorylation; Platelet Activating Factor; Progesterone; Protein-Tyrosine Kinases; Sperm Capacitation; Spermatozoa; Tyrosine

1995
Participation of diacylglycerol kinase in mitogenic signal transduction induced by platelet-derived growth factor in vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1994, Dec-15, Volume: 205, Issue:2

    Topics: Alkaloids; Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acid; Becaplermin; Cell Division; Cells, Cultured; Diacylglycerol Kinase; DNA; Enzyme Activation; Genistein; Humans; Isoflavones; Mitogens; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyrimidinones; Rats; Recombinant Proteins; Signal Transduction; Staurosporine; Thiazoles

1994
Protein tyrosine phosphorylation in equine platelets: the effect of stimulation by thrombin and platelet-activating factor (PAF)
    Equine veterinary journal, 1995, Volume: 27, Issue:6

    Topics: Animals; Blood Platelets; Blotting, Western; Cinnamates; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Horses; Isoflavones; Luminescent Measurements; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Thrombin; Time Factors

1995
Platelet-activating factor-induced inositol 1,4,5-trisphosphate generation in undifferentiated and differentiated U937 cells: role of tyrosine kinase.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:3

    Topics: Azepines; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Inositol 1,4,5-Trisphosphate; Isoflavones; Monocytes; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Triazoles

1996
Effect of lipopolysaccharide on mitogen-activated protein kinases and cytosolic phospholipase A2.
    The Biochemical journal, 1995, Jun-15, Volume: 308 ( Pt 3)

    Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Immunoblotting; Isoflavones; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Myelin Basic Protein; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Tyrosine

1995
Receptor-mediated and protein kinase-dependent growth enhancement of primary human fibroblasts by platelet activating factor.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:4

    Topics: Animals; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Genistein; Humans; Indomethacin; Infant, Newborn; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepharose; Skin; Staurosporine; Transcription, Genetic; Up-Regulation

1997
Pathways for eosinophil lipid body induction: differing signal transduction in cells from normal and hypereosinophilic subjects.
    Journal of leukocyte biology, 1998, Volume: 64, Issue:4

    Topics: Adult; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benzoquinones; Enzyme Inhibitors; Eosinophilia; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Inclusion Bodies; Interleukin-3; Interleukin-5; Lactams, Macrocyclic; Lipids; Phosphoproteins; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Quinones; Reference Values; Rifabutin; Signal Transduction

1998
Regulatory role of protein tyrosine phosphorylation in platelet activating factor-induced signal transduction in platelets.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:2

    Topics: Animals; Blood Platelets; Calcium; Genistein; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Rabbits; Serotonin; Signal Transduction

1999
A surrogate method for assessment of beta(2)-integrin-dependent adhesion of human eosinophils to ICAM-1.
    Journal of immunological methods, 2000, Jun-23, Volume: 240, Issue:1-2

    Topics: Androstadienes; Butadienes; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Eosinophils; Genistein; Humans; Hypersensitivity, Immediate; Integrins; Intercellular Adhesion Molecule-1; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Platelet Activating Factor; Protein Kinase Inhibitors; Serum Albumin, Bovine; Wortmannin

2000
Involvement of protein tyrosine kinases in activation of human eosinophils by platelet-activating factor.
    Immunology, 2000, Volume: 100, Issue:2

    Topics: Blotting, Western; Calcium; Cell Culture Techniques; Enzyme Inhibitors; Eosinophils; Genistein; Humans; Leukotriene C4; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Respiratory Burst

2000
Selective involvement of reactive oxygen intermediates in platelet-activating factor-mediated activation of NF-kappaB.
    Inflammation, 2000, Volume: 24, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Azepines; Benzoquinones; Disseminated Intravascular Coagulation; DNA-Binding Proteins; Female; Gene Expression Regulation; Genistein; Hemorrhage; Hydrogen Peroxide; I-kappa B Proteins; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Lethal Dose 50; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Platelet Activating Factor; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Edema; Pyrrolidines; Quinones; Reactive Oxygen Species; Rifabutin; Serine Proteinase Inhibitors; Signal Transduction; Specific Pathogen-Free Organisms; Succinic Acid; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone; Triazoles; Tumor Necrosis Factor-alpha; Vitamin E

2000
Effect of orthovanadate on platelet aggregation induced by platelet-activating factor.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-2 Receptor Antagonists; Albuterol; Animals; Butoxamine; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Propranolol; Rabbits; Receptors, Adrenergic, beta-2; Time Factors; Vanadates

2004
Enhancement of acetyl-CoA: 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity by hydrogen peroxide.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetyltransferases; Antioxidants; Arachidonic Acid; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Endothelial Cells; Genistein; Glutathione; Humans; Hydrogen Peroxide; Maleates; Oxidants; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Sulfonamides; Umbilical Veins

2007