1-hexadecyl-2-acetyl-glycero-3-phosphocholine and gabexate

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with gabexate in 6 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (gabexate)	Trials (gabexate)	Recent Studies (post-2010) (gabexate)
9,156	187	552	743	53	106

Protein Interaction Comparison

Protein	Taxonomy	gabexate (IC50)
Solute carrier family 22 member 2	Homo sapiens (human)	0.9
Coagulation factor X	Homo sapiens (human)	4.61
Plasminogen	Homo sapiens (human)	0.431
Urokinase-type plasminogen activator	Homo sapiens (human)	0.431
Serine protease hepsin	Homo sapiens (human)	0.383
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	0.5

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (33.33)	18.2507
2000's	3 (50.00)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hirano, T; Manabe, T	1
Imanishi, N; Komuro, Y; Morooka, S	1
Kistler, EB; Mitsuoka, H; Schmid-Schönbein, GW	1
Clavien, PA; Heinrich, S; Rousson, V; Schäfer, M	1
Bang, UC; Bendtsen, F; Nojgaard, C; Semb, S	1
Uomo, G	1

Reviews

2 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and gabexate

Article	Year
Evidence-based treatment of acute pancreatitis: a look at established paradigms. Annals of surgery, 2006, Volume: 243, Issue:2 Topics: Acute Disease; Anti-Bacterial Agents; Antibiotic Prophylaxis; Aprotinin; Cholecystectomy; Enteral Nutrition; Evidence-Based Medicine; Gabexate; Gastrointestinal Agents; Humans; Imidazoles; Imipenem; Leucine; Meropenem; Octreotide; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Randomized Controlled Trials as Topic; Serine Proteinase Inhibitors; Sphincterotomy, Endoscopic; Thienamycins	2006
Pharmacological approach to acute pancreatitis. World journal of gastroenterology, 2008, May-21, Volume: 14, Issue:19 Topics: Acute Disease; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Evidence-Based Medicine; Gabexate; Humans; Interleukin-10; Nitroglycerin; Octreotide; Pancreatitis; Platelet Activating Factor; Probiotics; Serine Proteinase Inhibitors; Treatment Outcome; Tumor Necrosis Factor-alpha	2008

Article

Year

Evidence-based treatment of acute pancreatitis: a look at established paradigms.

Annals of surgery, 2006, Volume: 243, Issue:2

Topics: Acute Disease; Anti-Bacterial Agents; Antibiotic Prophylaxis; Aprotinin; Cholecystectomy; Enteral Nutrition; Evidence-Based Medicine; Gabexate; Gastrointestinal Agents; Humans; Imidazoles; Imipenem; Leucine; Meropenem; Octreotide; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Randomized Controlled Trials as Topic; Serine Proteinase Inhibitors; Sphincterotomy, Endoscopic; Thienamycins

2006

Pharmacological approach to acute pancreatitis.

World journal of gastroenterology, 2008, May-21, Volume: 14, Issue:19

Topics: Acute Disease; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Evidence-Based Medicine; Gabexate; Humans; Interleukin-10; Nitroglycerin; Octreotide; Pancreatitis; Platelet Activating Factor; Probiotics; Serine Proteinase Inhibitors; Treatment Outcome; Tumor Necrosis Factor-alpha

2008

Other Studies

4 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and gabexate

Article	Year
"Cocktail" therapy for acute pancreatitis: combined therapy of protease inhibitor, xanthine oxidase inhibitor and platelet activating factor antagonist in rat caerulein-induced pancreatis. Nihon geka hokan. Archiv fur japanische Chirurgie, 1992, Nov-01, Volume: 61, Issue:6 Topics: Acute Disease; Allopurinol; Animals; Ceruletide; Drug Therapy, Combination; Gabexate; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Xanthine Oxidase	1992
Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC). Lipids, 1991, Volume: 26, Issue:12 Topics: Administration, Oral; Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrin Fibrinogen Degradation Products; Fibrinogen; Gabexate; Infusions, Intravenous; Injections, Intraperitoneal; Partial Thromboplastin Time; Platelet Activating Factor; Platelet Count; Prothrombin Time; Rats; Thiazoles; Thiazolidines	1991
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock. Shock (Augusta, Ga.), 2002, Volume: 17, Issue:3 Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; Inflammation; Intestinal Mucosa; Intestines; Leukocytes; Male; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Shock; Splanchnic Circulation; Survival Rate	2002
Lesson from acute experimental pancreatitis: multidrug strategies is effective than single-target therapy. JOP : Journal of the pancreas, 2012, Sep-10, Volume: 13, Issue:5 Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Gabexate; Humans; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreas; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats; Survival Analysis; Survival Rate; Treatment Outcome	2012