1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with fpl 55712 in 40 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (fpl 55712) | Trials (fpl 55712) | Recent Studies (post-2010) (fpl 55712) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 393 | 2 | 3 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | fpl 55712 (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.58 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.51 | |
| Thromboxane-A synthase | Homo sapiens (human) | 10 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.51 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 2.255 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (80.00) | 18.7374 |
| 1990's | 8 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Porsius, AJ; Vleeming, W; Wemer, J | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
| Bentwich, Z; Eliraz, A; Fink, A; Geva, D; Konichezky, S; Zung, A | 1 |
| Gimeno, AL; Gimeno, MA; González, E | 1 |
| Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P | 1 |
| Dembinska-Kiec, A; Muller, MK; Peskar, BA; Peskar, BM | 1 |
| Desquand, S; Lefort, J; Liu, FT; Mencia-Huerta, JM; Vargaftig, BB | 1 |
| Abraham, WM; Garrido, R; Stevenson, JS | 1 |
| Beck, G; Brzozowski, T; Drozdowicz, D; Garlicki, J; Konturek, SJ | 1 |
| Dembinska-Kiec, A; Novak, P; Peskar, BA; Peskar, BM | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Deacon, RW; Farley, C; Handley, DA; Saunders, RN | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Braquet, P; Clostre, F; Etienne, A; Touvay, C; Vilain, B | 1 |
| Piper, PJ; Stewart, AG | 3 |
| Arroyave, JL; Gonzalez-Crussi, F; Hsueh, W | 2 |
| Imura, Y; Nishikawa, K; Shino, A; Terashita, Z | 1 |
| Beck, G; Brzozowski, T; Drozdowicz, D; Konturek, SJ | 1 |
| Dembińska-Kieć, A; Peskar, BA; Peskar, BM | 1 |
| Armstead, WM; Busija, DW; Leffler, CW; Mirro, R; Pourcyrous, M | 1 |
| Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
| Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Braquet, P; Etienne, A; Touvay, C | 1 |
| Alloatti, G; Benedetto, C; Camussi, G; Emanuelli, G; Massobrio, M; Montrucchio, G; Roffinello, C; Tetta, C | 1 |
| Alloatti, G; Camussi, G; Emanuelli, G; Montrucchio, G; Roffinello, C; Tetta, C | 1 |
| Detsouli, A; Lefort, J; Vargaftig, BB | 1 |
| Chang, J; Dervinis, A; Lewis, AJ | 1 |
| Hechtman, HB; Shepro, D; Valeri, CR | 1 |
| Bessin, P; Bonnet, J; Thibaudeau, D | 1 |
| Bergmann, SR; Kenzora, JL; Lange, LG; Pérez, JE | 1 |
| O'Flaherty, JT; Stimler, NP | 1 |
| Boyd, LM; Ezra, D; Feuerstein, G; Goldstein, RE | 1 |
| Jaworek, J; Konturek, SJ | 1 |
| Asakura, K; Narita, S | 1 |
| Nishino, K; Ohashi, M; Uno, T | 1 |
1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and fpl 55712
| Article | Year |
|---|---|
Role of humoral mediators in adult respiratory distress syndrome.
Topics: Animals; Arachidonic Acids; Chemotaxis, Leukocyte; Chromones; Dogs; Guinea Pigs; Humans; Hypertension, Pulmonary; Inflammation; Ketanserin; Leukocyte Count; Leukocytes; Lung; Piperidines; Platelet Activating Factor; Pulmonary Embolism; Respiratory Distress Syndrome; Serotonin; Serotonin Antagonists; SRS-A; Thromboxane A2 | 1984 |
39 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and fpl 55712
| Article | Year |
|---|---|
Modulation of antigen- and ischemia-induced effects by the platelet-activating factor antagonist WEB-2086 in isolated sensitized rat hearts.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Chromatography, High Pressure Liquid; Chromones; Coronary Circulation; Heart; Histamine Release; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Platelet Activating Factor; Pressure; Rats; Rats, Wistar; Triazoles | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
Adult respiratory distress syndrome: roles of leukotriene C4 and platelet activating factor.
Topics: Adult; Chromones; Diterpenes; Ginkgolides; Humans; Infections; Lactones; Leukocyte Adherence Inhibition Test; Middle Aged; Platelet Activating Factor; Pulmonary Edema; Respiratory Distress Syndrome; SRS-A | 1990 |
A novel enhancing effect of platelet activating factor (PAF) on glucose oxidation in uteri from pregnant rats. Participation of prostaglandins and leukotrienes.
Topics: Animals; Carbon Monoxide; Chromones; Female; Glucose; Indomethacin; Leukotrienes; Masoprocol; Platelet Activating Factor; Pregnancy; Pregnancy, Animal; Prostaglandins; Rats; Rats, Inbred Strains; Uterus | 1990 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
The effects of platelet-activating factor on flow rate and eicosanoid release in the isolated perfused rat gastric vascular bed.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Flow Velocity; Chromatography, High Pressure Liquid; Chromones; Diterpenes; Gastric Mucosa; Ginkgolides; Indomethacin; Lactones; Lipoxygenase Inhibitors; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach; Thromboxane B2 | 1989 |
Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies.
Topics: Animals; Blood Cell Count; Bronchial Spasm; Chromones; Dinitrophenols; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunization, Passive; Immunoglobulin E; Lactones; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin, Bovine; SRS-A | 1989 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles | 1989 |
Role of leukotrienes and platelet activating factor in acute gastric mucosal lesions in rats.
Topics: Animals; Aspirin; Chromones; Diterpenes; Ethanol; Gastric Mucosa; Ginkgolides; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer; Stress, Psychological; Taurocholic Acid | 1989 |
Release of cysteinyl leukotrienes is of minor importance in platelet-activating factor-induced reduction of perfusion rate in the rat gastric vascular bed.
Topics: Animals; Benzofurans; Chromones; Gastric Mucosa; Leukotrienes; Lipoxygenase Inhibitors; Male; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach | 1989 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.
Topics: Animals; Chromones; Diphenhydramine; Dose-Response Relationship, Drug; Guinea Pigs; Hematocrit; Hemorrhage; Histamine; Injections, Intravenous; Leukotriene B4; Male; Phospholipid Ethers; Plasma; Platelet Activating Factor; SRS-A; Thiazoles; Time Factors | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Comparative effects of drugs on leukotrienes-, PAF-acether- and histamine- induced contractions of guinea-pig lung parenchymal strips.
Topics: Animals; Chromones; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene B4; Lung; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A | 1986 |
Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Vessels; Diterpenes; Furans; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indomethacin; Lactones; Leukotriene B4; Male; Perfusion; Plant Extracts; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thromboxane A2; Time Factors; Vasoconstriction | 1987 |
Platelet-activating factor-induced ischemic bowel necrosis. An investigation of secondary mediators in its pathogenesis.
Topics: Alprostadil; Animals; Blood Pressure; Catechols; Chromones; Diethylcarbamazine; Disease Models, Animal; Hematocrit; Indomethacin; Intestines; Ischemia; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Masoprocol; Methacrylates; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salmonella typhi; Thromboxane-A Synthase; Verapamil | 1986 |
Platelet-activating factor-induced vasoconstriction in rat isolated, perfused hearts: contribution of cyclo-oxygenase and lipoxygenase arachidonic acid metabolites.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Coronary Circulation; Diethylcarbamazine; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Myocardium; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Vasoconstriction | 1986 |
A lethal role of platelet activating factor in anaphylactic shock in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Dexamethasone; Male; Mice; Mice, Inbred Strains; Naloxone; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; SRS-A; Thiazoles | 1987 |
Role of leukotrienes in acute gastric lesions induced by ethanol, taurocholate, aspirin, platelet-activating factor and stress in rats.
Topics: Animals; Aspirin; Chromones; Dinoprostone; Ethanol; Female; Gastric Mucosa; Male; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer; Stress, Physiological; Taurocholic Acid | 1988 |
Release of cysteinyl-leukotrienes is of minor importance in PAF induced reduction of perfusion rate in the gastric vascular bed.
Topics: Animals; Chromones; Cysteine; Diterpenes; Ginkgolides; Indomethacin; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; SRS-A; Stomach | 1988 |
Platelet activating factor: a potent constrictor of cerebral arterioles in newborn pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Chromones; Dose-Response Relationship, Drug; Norepinephrine; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Reference Values; Swine | 1988 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis | 1988 |
Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chromones; Dinoprostone; Indomethacin; Intestine, Small; Methacrylates; Perfusion; Platelet Activating Factor; Prostaglandins E; Rats; SRS-A; Thromboxane B2; Vasoconstriction | 1986 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Actions of platelet-activating factor in the coronary circulation of the guinea pig in vitro.
Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Platelet Activating Factor; SRS-A | 1987 |
Inhibition of antigen-induced lung anaphylaxis in the guinea-pig by BN 52021 a new specific paf-acether receptor antagonist isolated from Ginkgo biloba.
Topics: Anaphylaxis; Animals; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Male; Plant Extracts; Platelet Activating Factor | 1986 |
Platelet-activating factor contracts human myometrium in vitro.
Topics: Adult; Chromones; Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Phospholipid Ethers; Platelet Activating Factor; Pregnancy; Thiazoles; Uterine Contraction | 1986 |
In vitro contractile effect of platelet-activating factor on guinea-pig myometrium.
Topics: Animals; Chromones; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Myometrium; Oxytocin; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins; Thiazoles; Uterine Contraction | 1986 |
Histamine and leukotriene-independent guinea-pig anaphylactic shock unaccounted for by Paf-acether.
Topics: Acetophenones; Anaphylaxis; Animals; Catechols; Chromones; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Masoprocol; Muscle Contraction; Platelet Activating Factor; SRS-A | 1985 |
The effects of antiallergic and bronchodilator drugs on platelet-activating factor (PAF-acether) induced bronchospasm and platelet aggregation.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Chromones; Cromolyn Sodium; Guinea Pigs; Histamine H1 Antagonists; Male; Platelet Activating Factor; Platelet Aggregation; Promethazine; Rabbits | 1984 |
Dependency of the Paf-acether induced bronchospasm on the lipoxygenase pathway in the guinea-pig.
Topics: Animals; Bronchial Spasm; Catechols; Chromones; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Lipoxygenase Inhibitors; Maleates; Masoprocol; Phenindione; Platelet Activating Factor; Propionates | 1983 |
Effects of acetyl glyceryl ether of phosphorylcholine (platelet activating factor) on ventricular preload, afterload, and contractility in dogs.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cattle; Chromones; Diethylcarbamazine; Dogs; Guinea Pigs; Hemodynamics; Myocardial Contraction; Platelet Activating Factor; Pulmonary Circulation; Rabbits; SRS-A; Vascular Resistance; Ventricular Function | 1984 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
Effect of platelet-activating factor on coronary circulation of the domestic pig.
Topics: Animals; Blood Pressure; Chromones; Coronary Circulation; Female; Heart Rate; Indomethacin; Male; Platelet Activating Factor; Swine; Vascular Resistance | 1984 |
Effects of prostaglandin of E, F and I series, leukotriene C and platelet activating factor on amylase release from isolated rat pancreatic acini.
Topics: Acetamides; Amylases; Animals; Bethanechol Compounds; Ceruletide; Chromones; Dinoprostone; Epoprostenol; Indomethacin; Isoquinolines; Leukotriene C4; Male; Pancreas; Phenyl Ethers; Platelet Activating Factor; Prostaglandin Antagonists; Prostaglandins; Prostaglandins F; Prostaglandins F, Synthetic; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines | 1993 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Effect of ibudilast, a novel antiasthmatic agent, on anaphylactic bronchoconstriction: predominant involvement of endogenous slow reacting substance of anaphylaxis.
Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Asthma; Bronchoconstriction; Bronchodilator Agents; Calcimycin; Chromones; Guinea Pigs; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyrazoles; Pyridines; SRS-A | 1993 |