1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with foropafant in 29 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (foropafant) | Trials (foropafant) | Recent Studies (post-2010) (foropafant) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 37 | 4 | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (89.66) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herbert, JM | 1 |
| Herbert, JM; Laplace, MC; Maffrand, JP | 2 |
| Bernat, A; Herbert, JM; Lespy, L; Maffrand, JP; Salel, V | 1 |
| Bernat, A; Herbert, JM; Laplace, MC; Maffrand, JP; Salel, V | 1 |
| Bernat, A; Gigo, V; Herbert, JM; Lale, A; LaPlace, MC; Le Fur, G; Lespy, L; Maffrand, JP; Savi, P; Valette, G | 1 |
| Herbert, JM; Lespy, L; Maffrand, JP | 1 |
| Fang, G; Fonteles, M; Guerrant, RL; Thielman, NM; Yotseff, PS | 1 |
| Dol, F; Herbert, JM; Laplace, MC; Mares, AM | 1 |
| Bado, A; Braquet, P; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I; Tarrade, T | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Heard, SO; Perkins, M; Toth, I | 1 |
| Dikshit, M; Kumari, R; Seth, P; Srimal, RC | 1 |
| Fang, GD; Fonteles, MC; Guerrant, RL; Thielman, NM | 1 |
| Bernat, A; Herbert, JM | 1 |
| Cailleau, C; Herbert, JM; Laplace, MC; Maffrand, JP | 1 |
| Giudice, A; Herbert, JM; Le Fur, G; Maffrand, JP; Manara, L; Manzoni, L | 1 |
| Bernat, A; Corseaux, D; Herbert, JM; Lale, A | 1 |
| Bernat, A; Herbert, JM; Tibiriça, E | 1 |
| Fang, GD; Guerrant, RL; Marcinkiewicz, M; Sarosiek, J; Thielman, NM | 1 |
| Barnes, PJ; Cluzel, M; Evans, DJ; O'Connor, BJ | 1 |
| Barbosa-Filho, JM; Castro-Faria-Neto, HC; Cordeiro, RS; Herbert, JM; Tibiriça, E | 1 |
| Bruyneel, E; Chastre, E; Gespach, C; Kotelevets, L; Mareel, M; Myssiakine, E; Noë, V | 1 |
| Barberà, JA; Chung, KF; Gómez, FP; Peinado, VI; Roca, J; Rodriguez-Roisin, R | 1 |
| Hawkey, CJ; Jenkins, D; Stack, WA; Vivet, P | 1 |
| Barberà, JA; Chung, KF; Gómez, FP; Iglesia, R; Marrades, RM; Roca, J; Rodriguez-Roisin, RM | 1 |
| Berthou, C; Bourge, JF; Denizot, Y; Geromin, D; Sasportes, M; Sigaux, F; Soulié, A; Zhang, Y | 1 |
| Allaume, P; Cheminade, C; Gautier, V; Hichami, A; Le Lannou, D; Legrand, AB | 1 |
| Bélanger, C; Borgeat, P; Elimam, H; Lefebvre, J; Marleau, S | 1 |
4 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and foropafant
| Article | Year |
|---|---|
Effects of a potent platelet-activating factor antagonist, SR27417A, on allergen-induced asthmatic responses.
Topics: Adult; Allergens; Asthma; Cross-Over Studies; Double-Blind Method; Forced Expiratory Volume; Humans; Male; Platelet Activating Factor; Thiazoles | 1997 |
Effect of a platelet-activating factor (PAF) antagonist, SR 27417A, on PAF-induced gas exchange abnormalities in mild asthma.
Topics: Adult; Airway Resistance; Asthma; Blood Gas Analysis; Female; Humans; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Pulmonary Gas Exchange; Thiazoles | 1998 |
Lack of effectiveness of the platelet-activating factor antagonist SR27417A in patients with active ulcerative colitis: a randomized controlled trial. The Platelet Activating Factor Antagonist Study Group in Ulcerative Colitis.
Topics: Adult; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Thiazoles | 1998 |
Gas exchange response to a PAF receptor antagonist, SR 27417A, in acute asthma: a pilot study.
Topics: Acute Disease; Adult; Airway Resistance; Asthma; Blood Flow Velocity; Blood Gas Analysis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Pulmonary Circulation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Ventilation-Perfusion Ratio | 1999 |
25 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and foropafant
| Article | Year |
|---|---|
Characterization of specific binding sites of 3H-labelled platelet-activating factor ([3H]PAF) and a new antagonist, [3H]SR 27417, on guinea-pig tracheal epithelial cells.
Topics: Animals; Binding Sites; Cells, Cultured; Epithelial Cells; Epithelium; Guinea Pigs; Kinetics; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Trachea; Tritium | 1992 |
Ex vivo effects of SR 27417, a novel PAF antagonist, on rabbit platelet aggregation and [3H]-PAF binding.
Topics: Administration, Oral; Animals; Blood Platelets; Dose-Response Relationship, Drug; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Statistics as Topic; Thiazoles | 1992 |
Protective effect of SR 27417, a novel PAF antagonist, on PAF- or endotoxin-induced hypotension in the rat and the guinea-pig.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Endotoxins; Guinea Pigs; Hypotension; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles | 1992 |
Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigen.
Topics: Allergens; Animals; Antigens; Edema; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Skin Diseases; Thiazoles | 1992 |
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Guinea Pigs; Humans; Injections, Intravenous; Leukopenia; Male; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thrombocytopenia; Triazoles | 1991 |
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles | 1991 |
Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A.
Topics: Actins; Animals; Bacterial Toxins; Enteritis; Enterotoxins; Epithelium; Ileum; Intestinal Mucosa; Intestines; Male; Phalloidine; Platelet Activating Factor; Rabbits; Rhodamines; Staining and Labeling; Thiazoles | 1995 |
Platelet-activating factor (PAF) is not an essential component of the cascade leading to smooth muscle cell proliferation following vascular injury.
Topics: Animals; Aorta; Cell Division; Endothelium, Vascular; Hyperplasia; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thiazoles; Vascular Diseases | 1995 |
Platelet-activating factor stimulates gastric acid secretion in isolated rabbit gastric glands.
Topics: Aminopyrine; Animals; Azepines; Biological Transport; Calcium; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Famotidine; Fluorescent Dyes; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rabbits; Thiazoles; Thienopyridines; Triazoles; Verapamil | 1995 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
The role of platelet-activating factor in lipopolysaccharide-induced myocardial depression in guinea pigs.
Topics: Animals; Azepines; Depression, Chemical; Drug Interactions; Escherichia coli; Female; Guinea Pigs; Isoproterenol; Lipopolysaccharides; Male; Myocardial Contraction; Phenylephrine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Time Factors; Triazoles | 1995 |
Effect of platelet activating factor antagonists in different models of thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Azepines; Cats; Diterpenes; Ginkgolides; Lactones; Male; Mice; Mice, Inbred Strains; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombophlebitis; Triazoles | 1994 |
Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin.
Topics: Animals; CHO Cells; Cholera Toxin; Cricetinae; Cytoskeleton; Diterpenes; Epithelium; Ginkgolides; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Lactones; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles | 1994 |
Effect of various drugs on adriamycin-enhanced venous thrombosis in the rat: importance of PAF.
Topics: Animals; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Doxorubicin; Leukocyte Count; Male; Platelet Activating Factor; Platelet Count; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombophlebitis; Ticlopidine | 1994 |
Binding of [3H]SR 27417, a novel platelet-activating factor (PAF) receptor antagonist, to rabbit and human platelets and polymorphonuclear leukocytes.
Topics: Animals; Binding Sites; Binding, Competitive; Blood Platelets; Dose-Response Relationship, Drug; Humans; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles | 1993 |
Effect of SR 27417 on the binding of [3H]PAF to rabbit and human platelets and human polymorphonuclear leukocytes.
Topics: Animals; Blood Platelets; Humans; Molecular Structure; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Tritium | 1993 |
Prevention of platelet-activating factor-induced gastrointestinal lesions in rats by the new specific antagonist N-(2-dimethylaminoethyl)-N-(3-pyridinylmethyl)[4-(2,4,6-triisopropylphe nyl) thiazol-2yl]amine.
Topics: Animals; Azepines; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Diseases; Intestinal Mucosa; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Thiazoles; Triazoles | 1996 |
Hypoxia primes endotoxin-induced tissue factor expression in human monocytes and endothelial cells by a PAF-dependent mechanism.
Topics: Animals; Cells, Cultured; Endotoxins; Humans; Hypoxia; Interleukin-1; Lipopolysaccharides; Monocytes; Platelet Activating Factor; Rabbits; Thiazoles; Thrombophlebitis; Thromboplastin; Umbilical Cord | 1996 |
Effect of SR 27417, a novel PAF antagonist on antigen-induced hypotension in the rat.
Topics: Animals; Antigens; Hypotension; Male; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin.
Topics: Alprostadil; Animals; Bucladesine; Cell Size; CHO Cells; Cholera Toxin; Cricetinae; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Diterpenes; Ginkgolides; Humans; Lactones; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles | 1997 |
Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin.
Topics: Animals; Blood Platelets; Furans; Guinea Pigs; Humans; Interleukin-1; Interleukin-6; Kinetics; Leukocytes; Leukopenia; Lignans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Thiazoles; Thrombocytopenia; Tumor Necrosis Factor-alpha | 1997 |
Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.
Topics: Androstadienes; Animals; Azepines; Cell Adhesion Molecules; Cell Movement; Chromones; Colonic Neoplasms; Dogs; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, src; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Thiazoles; Transformation, Genetic; Triazoles; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wortmannin | 1998 |
Interferon-gamma-induced membrane PAF-receptor expression confers tumor cell susceptibility to NK perforin-dependent lysis.
Topics: Adult; Azepines; Calcium; Cell Membrane; Cytotoxicity, Immunologic; Gene Expression; Humans; Interferon-gamma; Killer Cells, Natural; Membrane Glycoproteins; Neoplasms; Perforin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pore Forming Cytotoxic Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Transfection; Triazoles; Tumor Cells, Cultured | 2000 |
1-O-alkylglycerols improve boar sperm motility and fertility.
Topics: Animals; Buffers; Cell Survival; Chromatography, High Pressure Liquid; Female; Fertility; Fertilization; Glycerol; In Vitro Techniques; Indicators and Reagents; Insemination, Artificial; Lipid Metabolism; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sperm Motility; Spermatozoa; Stimulation, Chemical; Swine; Thiazoles | 2002 |
Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats.
Topics: Animals; Benzopyrans; Carboxylic Acids; Dermatitis; Dihydropyridines; Imidazoles; Leukotriene B4; Male; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Skin; Thiazoles | 2008 |