Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and fluorouracil

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with fluorouracil in 4 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
9,15618755245,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Comte, L; Denizot, Y; Dulery, C; Dupuis, F; Praloran, V1
Denizot, Y; Dupuis, F; Praloran, V; Roullet, B1
Brito, GA; Cunha, FQ; Justino, PF; Lima-Junior, RC; Mota, JM; Ribeiro, RA; Soares, PM; Souza, MH1
Abdalla, AM; Abdelbaky, FAF; Abdelzaher, WY; Hafez, SMNA; Khalaf, HM; Welson, NN1

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and fluorouracil

ArticleYear
PAF and hematopoiesis. II. Elevated levels of plasma paf acetylhydrolase after rapid infusion of 5-fluorouracil in cancer patients.
    Cancer letters, 1994, Oct-14, Volume: 85, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Female; Fluorouracil; Hematopoiesis; Humans; Male; Middle Aged; Phospholipases A; Platelet Activating Factor

1994

Other Studies

3 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and fluorouracil

ArticleYear
PAF and haematopoiesis. IV. Modifications of spleen and thymus PAF contents after a single dose of the chemotherapeutic drug 5-fluorouracil in mice.
    Cancer letters, 1995, Jan-27, Volume: 88, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Blood Cell Count; Bone Marrow; Fluorouracil; Hematopoiesis; Male; Mice; Phospholipases A; Platelet Activating Factor; Spleen; Thymus Gland

1995
Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Cytokines; Duodenum; Fluorouracil; Ginkgolides; Intestinal Diseases; Intestinal Mucosa; Lactones; Leukocyte Count; Leukopenia; Mice; Mice, Inbred BALB C; Mice, Knockout; Mucositis; Peroxidase; Platelet Activating Factor; Receptors, Platelet-Derived Growth Factor

2011
Role of Platelet-activating factor and HO-1 in mediating the protective effect of rupatadine against 5-fluorouracil-induced hepatotoxicity in rats.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:26

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyproheptadine; Fluorouracil; Heme Oxygenase-1; Liver; Male; Oxidative Stress; Platelet Activating Factor; Rats

2022