1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with e 6123 in 22 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (e 6123) | Trials (e 6123) | Recent Studies (post-2010) (e 6123) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 28 | 0 | 0 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (86.36) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawahara, T; Machida, Y; Miyazawa, S; Okano, K; Yamatsu, I | 1 |
| Katayama, K; Katayama, S; Sakuma, Y; Shirato, M; Tsunoda, H; Yamatsu, I | 1 |
| Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
| Asano, O; Clark, RS; Kawahara, T; Miyamoto, M; Miyazawa, S; Muramoto, K; Okano, K; Sakuma, Y; Shimomura, N; Yoshimura, H | 1 |
| Katayama, K; Katayama, S; Nagaoka, J; Obaishi, H; Ono, H; Sakuma, Y; Shirato, M; Tsunoda, H | 1 |
| Harada, K; Katayama, K; Machida, Y; Obaishi, H; Sakuma, Y; Shimomura, N; Shirato, M; Tsunoda, H; Yamada, K; Yamatsu, I | 1 |
| Clark, R; Harada, K; Horie, T; Katayama, S; Miyazawa, S; Muramoto, K; Okano, K; Sakuma, Y; Shimomura, N; Tsunoda, H | 2 |
| Harada, K; Katayama, S; Machida, Y; Miyazawa, S; Obaishi, H; Okano, K; Sakuma, Y; Shirato, M; Tsunoda, H; Yamada, K | 1 |
| Fu, L; Ikeda, H; Kaneko, T; Nishiyama, H; Okubo, T | 1 |
| Abe, K; Daling, Z; Horie, T; Nakamura, T; Tanaka, E | 1 |
| Abe, Y; Ida, S; Kagei, Y; Kusano, K; Miyazawa, S; Tadano, K; Tanaka, S; Ueda, M; Yuzuriha, T | 1 |
| Abe, Y; Ida, S; Kusano, K; Tanaka, S; Yuzuriha, T | 1 |
| Abe, Y; Ando, T; Ida, S; Kusano, K; Tanaka, S; Yuzuriha, T | 1 |
| Fujimura, M; Matsuda, T; Myou, S; Songür, N; Tsujiura, M | 1 |
| Fukuda, T; Makino, S; Sagara, H | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M | 2 |
| Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Nakano, H; Shigyo, M; Takata, S | 1 |
| Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Komori, M; Koto, H; Matsumoto, K | 1 |
| Ichinowatari, G; Ohuchi, K; Tanimoto, A; Tsuyuki, K; Yaginuma, H; Yamada, M | 2 |
1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and e 6123
| Article | Year |
|---|---|
[PAF receptor antagonist in asthma therapy].
Topics: Animals; Asthma; Azepines; Humans; Platelet Activating Factor; Triazoles | 1996 |
21 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and e 6123
| Article | Year |
|---|---|
Hapten synthesis for (+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tet rahydro-8H-pyrido[4',3':4,5]thieno[3,2-f] triazolo[4,3-a][1,4]diazepine (E6123).
Topics: Azepines; Chromatography; Haptens; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Platelet Activating Factor; Radioimmunoassay; Triazoles | 1992 |
Pharmacological effects of oral E6123, a novel PAF antagonist, on biological changes induced by PAF inhalation in guinea pigs.
Topics: Administration, Oral; Analysis of Variance; Animals; Asthma; Azepines; Bronchial Hyperreactivity; Bronchoconstriction; Calcium; Eosinophils; Guinea Pigs; Lung; Male; Platelet Activating Factor; Triazoles | 1991 |
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Structure-activity studies on triazolothienodiazepine derivatives as platelet-activating factor antagonists.
Topics: Animals; Azepines; Blood Platelets; Guinea Pigs; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Activation; Structure-Activity Relationship; Triazoles | 1991 |
Pharmacological activities of a novel thienodiazepine derivative as a platelet-activating factor antagonist. Effects on microvascular permeability, hypotension and nephrosis.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Endotoxins; Guinea Pigs; Male; Nephrosis; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Triazoles | 1991 |
Activity of a novel thienodiazepine derivative as a platelet-activating factor antagonist in guinea pig lungs. Effects on platelet-activating factor and allergen induced eosinophil accumulation.
Topics: Aerosols; Animals; Azepines; Bronchoalveolar Lavage Fluid; Eosinophils; Guinea Pigs; Leukocyte Count; Lung; Male; Methylprednisolone; Platelet Activating Factor; Triazoles | 1991 |
Effects of a novel PAF antagonist, E6123, on PAF-induced biological responses.
Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Bronchoconstrictor Agents; Dogs; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Platelet Activating Factor; Platelet Aggregation; Triazoles | 1990 |
Effects of a novel PAF antagonist, E6123, on passive anaphylaxis.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Bronchoconstriction; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Triazoles | 1990 |
Pharmacological activities of a novel thienodiazepine derivative as a platelet-activating factor antagonist.
Topics: Administration, Oral; Animals; Azepines; Blood Platelets; Bronchoconstriction; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Injections, Intravenous; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Species Specificity; Triazoles | 1990 |
Platelet-activating factor mediates the ozone-induced increase in airway microvascular leakage in guinea pigs.
Topics: Animals; Azepines; Bronchi; Capillary Permeability; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Inflammation Mediators; Male; Ozone; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Physiological Phenomena; Respiratory System; Trachea; Triazoles | 1995 |
Dual effects of a novel thienodiazepine platelet-activating factor antagonist, on drug-oxidizing enzymes in beagle dog.
Topics: Animals; Antipyrine; Azepines; Cytochrome P-450 Enzyme System; Dogs; Half-Life; Male; Metabolic Clearance Rate; Microsomes, Liver; Nitroanisole O-Demethylase; Oxidoreductases, N-Demethylating; Platelet Activating Factor; Regression Analysis; Triazoles; Trimethadione | 1994 |
Development of radioimmunoassay for the novel platelet activating factor receptor antagonist, E6123, and its application to pharmacokinetics in laboratory animals.
Topics: Animals; Azepines; Biological Availability; Chromatography, High Pressure Liquid; Cross Reactions; Dogs; Guinea Pigs; Haptens; Immune Sera; Macaca mulatta; Male; Platelet Activating Factor; Rabbits; Radioimmunoassay; Sensitivity and Specificity; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Triazoles | 1994 |
Pharmacokinetics of a new thienodiazepine platelet activating factor receptor antagonist (E6123) in laboratory animals. Is there a metabolic polymorphism in the rhesus monkey?
Topics: Animals; Azepines; Biological Availability; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Guinea Pigs; Macaca mulatta; Male; Platelet Activating Factor; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Triazoles | 1993 |
Metabolic polymorphism of E6123 in rhesus monkey.
Topics: Animals; Azepines; Erythrocytes; Feces; Hydrogen-Ion Concentration; Kinetics; Macaca mulatta; Male; Platelet Activating Factor; Polymorphism, Genetic; Triazoles | 1993 |
Involvement of PAF in postallergic propranolol-induced bronchoconstriction in guinea-pigs.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Antigens; Asthma; Azepines; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Hypersensitivity; Immunization; Inflammation Mediators; Injections, Intravenous; Male; Platelet Activating Factor; Propranolol; Respiration, Artificial; Time Factors; Triazoles | 1996 |
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages.
Topics: Acyltransferases; Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1998 |
Eosinophilic airway inflammation induced by repeated exposure to cigarette smoke.
Topics: Animals; Azepines; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Nicotiana; Plants, Toxic; Platelet Activating Factor; Pulmonary Eosinophilia; Smoke; Time Factors; Triazoles | 1998 |
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages.
Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
PAF mediates cigarette smoke-induced goblet cell metaplasia in guinea pig airways.
Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Goblet Cells; Guinea Pigs; Male; Metaplasia; Nicotiana; Peroxidase; Plants, Toxic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Smoke; Trachea; Triazoles | 2001 |
Participation of prostaglandin E2 and platelet-activating factor in thapsigargin-induced production of interleukin-6.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Animals; Azepines; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Interleukin-6; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thapsigargin; Triazoles | 2002 |
Possible participation of intracellular platelet-activating factor in NF-kappaB activation in rat peritoneal macrophages.
Topics: Animals; Azepines; Base Sequence; Cells, Cultured; DNA Primers; Hydrolysis; Imidazoles; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Organophosphorus Compounds; Phosphorylation; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Thapsigargin; Triazoles | 2002 |