1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with diphenhydramine in 9 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (diphenhydramine) | Trials (diphenhydramine) | Recent Studies (post-2010) (diphenhydramine) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 4,146 | 415 | 542 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | diphenhydramine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.98 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.542 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.05 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.372 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.162 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.346 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.647 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.542 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 1.295 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.98 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.171 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.118 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.8852 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Driscoll, EM; Jackson, CV; Kunkel, SL; Lucchesi, BR; Schumacher, WA | 1 |
| Deacon, RW; Farley, C; Handley, DA; Saunders, RN | 1 |
| Darius, H; Lefer, AM; Smith, JB | 1 |
| Darius, H; Lefer, AM; Lefer, DJ; Smith, JB | 1 |
| Darius, H; Lefer, AM | 1 |
| Lu, Z; Wolf, MB | 1 |
| Makiyama, Y; Mitsui, Y; Tanaka, Y | 1 |
| Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H; Zhang, W | 1 |
| Kuda, Y; Kurata, Y; Shibamoto, T; Tanida, M; Wang, M | 1 |
9 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and diphenhydramine
| Article | Year |
|---|---|
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
Topics: Animals; Aspirin; Coronary Circulation; Coronary Vessels; Diphenhydramine; Dogs; Histamine H1 Antagonists; Male; Methacholine Compounds; Methysergide; Nitroglycerin; Platelet Activating Factor; Thrombocytopenia; Vasodilation | 1986 |
Evidence for distinct systemic extravasation effects of platelet activating factor, leukotrienes B4, C4, D4 and histamine in the guinea pig.
Topics: Animals; Chromones; Diphenhydramine; Dose-Response Relationship, Drug; Guinea Pigs; Hematocrit; Hemorrhage; Histamine; Injections, Intravenous; Leukotriene B4; Male; Phospholipid Ethers; Plasma; Platelet Activating Factor; SRS-A; Thiazoles; Time Factors | 1986 |
Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists.
Topics: Alprazolam; Anaphylaxis; Animals; Benzodiazepines; Benzofurans; Benzopyrans; Diphenhydramine; Guinea Pigs; Histamine; Lignans; Male; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A | 1986 |
Role of platelet-activating factor-acether in mediating guinea pig anaphylaxis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alprazolam; Anaphylaxis; Animals; Anti-Inflammatory Agents; Benzodiazepines; Blood Pressure; Diphenhydramine; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyrazoles | 1986 |
Pharmacologic antagonism of platelet activating factor and peptide leukotrienes inhibits guinea pig anaphylaxis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Blood Pressure; Diphenhydramine; Guinea Pigs; In Vitro Techniques; Lignans; Lung; Male; Platelet Activating Factor; Platelet Count; Pyrazoles | 1987 |
Platelet activating factor-induced microvascular permeability increases in the cat hindlimb.
Topics: Animals; Azepines; Capillary Permeability; Cats; Cimetidine; Diphenhydramine; Endothelium, Vascular; Hindlimb; Histamine; Isoproterenol; Leukocyte Count; Leukocytes; Platelet Activating Factor; Triazoles | 1993 |
Anti-CD44 monoclonal antibody (IM7) induces murine systemic shock mediated by platelet activating factor.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Antibodies, Monoclonal; Azepines; Capillary Permeability; Cyproheptadine; Diphenhydramine; Erythrocytes; Hyaluronan Receptors; Hypotension; Immunoglobulin Fab Fragments; Immunoglobulin G; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Platelet Activating Factor; Triazoles | 2002 |
PAF, rather than histamine, participates in mouse anaphylactic hypotension.
Topics: Anaphylaxis; Animals; Blood Pressure; Diphenhydramine; Histamine; Histamine H1 Antagonists; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Receptors, Histamine H1 | 2008 |
Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine.
Topics: Anaphylaxis; Animals; Arterial Pressure; Cardiac Output; Diphenhydramine; Hemodynamics; Histamine; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Vascular Resistance; Vasoconstriction; Vasodilation | 2014 |