1-hexadecyl-2-acetyl-glycero-3-phosphocholine and dihydropyridines

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with dihydropyridines in 52 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (dihydropyridines)	Trials (dihydropyridines)	Recent Studies (post-2010) (dihydropyridines)
9,156	187	552	5,022	529	969

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	32 (61.54)	18.2507
2000's	11 (21.15)	29.6817
2010's	9 (17.31)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alonso, MT; Sanchez, A; Villalobos, C	1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB	1
Cooper, K; Fray, MJ; Parry, MJ; Richardson, K; Steele, J	1
Achiwa, K; Ebiike, H; Maruyama, K	1
Alabaster, VA; de Souza, RN; Keir, RF; Parry, MJ	1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Correia-Da-Silva, AC; Martins, MA; Morhy, L; Sousa, MV	1
de Casa-Juana, MF; García, MC; Gijón, MA; Ortega, MP; Priego, JG; Sanchez Crespo, M; Sunkel, C	1
de Casa-Juana, MF; Fernández-Gallardo, S; Ortega, MP; Priego, JG; Sánchez Crespo, M; Sunkel, C	1
de Casa-Juana, MF; Gómez, MM; González-Morales, MA; Ortega, MP; Priego, JG; Santos, L; Sunkel, CE; Villarroya, M	1
Aragonés, MD; Catalán, RE; Garde, E; Lombardía, M; Martínez, AM	1
Bull, DJ; Cooper, K; Fray, MJ; Parry, MJ; Stefaniak, MH	1
Desquand, S; Hatmi, M; Lefort, J; Pina, M; Priego, JG; Ruffié, C; Vargaftig, BB	1
Kase, N; Ohnishi, H; Tamura, N; Yamaura, T	1
Das, A; Larkin, SW; Nourshargh, S; Williams, TJ	1
Angus, RM; Barnes, NC; Barnes, PJ; Bone, MF; Chung, KF; Fairfax, AJ; Higenbotham, TW; Kuitert, LM; O'Connor, BJ; Piotrowska, B	1
Alabaster, VA; Cheeseman, HE; Cooper, K; deSouza, RN; Keir, RF; Parry, MJ	1
Bolanowski, MA; Nourshargh, S; Sanz, MJ; Weg, VB	1
Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ	1
Aragonés, MD; Catalán, RE; Garde, E; Hernández, F; Lombardía, M; Martínez, AM	1
Aragonés, MD; Calcerrada, MC; Catalán, RE; Fernández, I; Martínez, AM; Miguel, BG; Pérez, MJ	1
Barnes, PJ; Carty, TJ; Chung, KF; Eskra, JD; O'Connor, BJ; Uden, S	1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Larangeira, AP; Martins, MA; Silva, AR; Silva, PM	1
Amorim, CZ; Cordeiro, RS; Vargaftig, BB	1
Aragonés, MD; Catalán, RE; Garde, E; Lombardía, M; Martínez, AM; Ortega, P	1
Bozza, PT; Cordeiro, RS; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Sunkel, CE	1
Barnes, NC; Burke, W; Hui, KP; Kuitert, LM; Newland, AC; Uden, S; Uthayarkumar, S	1
Norman, KE; Nourshargh, S; Pons, F; Rossi, AG; Williams, TJ	1
Calcerrada, MC; Catalán, RE; Hernández, F; Martínez, AM; Pérez, MJ	1
Chilvers, ER; Condliffe, AM; Haslett, C; Kitchen, E; Rossi, AG	1
Ferreira, MG; Fonteles, MC	1
Norman, KE; Rossi, AG; Williams, TJ	1
Hellewell, PG; Jeffery, PK; Miotla, JM	1
Benjamim, CF; Cunha, Fde Q; Ferreira, SH; Rios-Santos, F; Zavery, D	1
Ishii, S; Pinho, V; Shimizu, T; Soares, AC; Souza, DG; Teixeira, MM	1
Andrade, SP; Barcelos, LS; Campos, PP; Ferreira, MA; Teixeira, MM; Vasconcelos, AC	1
Bolsover, S; Ranasinghe, S	1
Bazan, HE; He, J	1
Byrne, SN; Matsumura, Y; Miyahara, Y; Nghiem, DX; Ullrich, SE	1
Day, ML; Li, Y; O'Neill, C	1
Bar-Eli, M; Melnikova, V	1
Boedker, M; Boetkjaer, A; Cui, JG; Lukiw, WJ; Zhao, Y	1
Bélanger, C; Borgeat, P; Elimam, H; Lefebvre, J; Marleau, S	1
Alvarez-Builla, J; Atkins, K; Bazan, NG; Belayev, L; Gordon, WC; Khoutorova, L	1
Borgeat, P; Flamand, N; Lefebvre, JS; Lévesque, T; Marleau, S; Milot, V; Picard, S	1
Bazan, HE; Eastlack, JP; He, J	1
Cassali, GD; Fagundes, CT; Garcia, CC; Guabiraba, R; Machado, AV; Polidoro, RB; Russo, RC; Salgado, AP; Sousa, LP; Tavares, LP; Teixeira, MM	1
Musto, AE; Samii, M	1
Bambach, I; Huettner, B; Koefeler, H; Mayer, G; Schön, MP; Singh, TP; Wallbrecht, K; Wolf, P	1
Broccatelli, F; Budriesi, R; Carosati, E; Chiarini, A; Cruciani, G; Ioan, P; Micucci, M; Zhorov, BS	1
Bazan, HE; He, J; Kakazu, A; Kenchegowda, S	1
Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC	1
Borges, AF; de Oliveira, MAP; Dorta, ML; Gomes, RS; Morato, CI; Ribeiro-Dias, F	1

Reviews

2 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and dihydropyridines

Article	Year
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor. Cancer metastasis reviews, 2007, Volume: 26, Issue:3-4 Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Humans; Inflammation; Lung Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Melanoma; Neovascularization, Pathologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteins; Receptors, G-Protein-Coupled; Signal Transduction	2007
1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 2): action in other targets and antitargets. Current medicinal chemistry, 2012, Volume: 19, Issue:25 Topics: Alzheimer Disease; Animals; Antitubercular Agents; Atherosclerosis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydropyridines; Drug Resistance, Multiple; Humans; Platelet Activating Factor; Tuberculosis	2012

Article

Year

Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.

Cancer metastasis reviews, 2007, Volume: 26, Issue:3-4

Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Humans; Inflammation; Lung Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Melanoma; Neovascularization, Pathologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteins; Receptors, G-Protein-Coupled; Signal Transduction

2007

1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 2): action in other targets and antitargets.

Current medicinal chemistry, 2012, Volume: 19, Issue:25

Topics: Alzheimer Disease; Animals; Antitubercular Agents; Atherosclerosis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydropyridines; Drug Resistance, Multiple; Humans; Platelet Activating Factor; Tuberculosis

2012

Trials

3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and dihydropyridines

Article	Year
Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthma. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:5 Topics: Adult; Aged; Asthma; Dihydropyridines; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Imidazoles; Male; Middle Aged; Peak Expiratory Flow Rate; Platelet Activating Factor; Quality of Life; Single-Blind Method	1995
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans. American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:1 Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Bronchoconstriction; Dihydropyridines; Dose-Response Relationship, Drug; Double-Blind Method; Eicosanoids; Humans; Imidazoles; Leukocyte Count; Leukotriene E4; Male; Neutropenia; Neutrophils; Platelet Activating Factor; Thromboxane B2	1994
Effect of the platelet-activating factor antagonist UK-74,505 on the early and late response to allergen. The American review of respiratory disease, 1993, Volume: 147, Issue:1 Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Dihydropyridines; Double-Blind Method; Forced Expiratory Volume; Humans; Imidazoles; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation	1993

Other Studies

47 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and dihydropyridines

Article	Year
Effects of the antithrombitic agent PCA 4230 on agonist-induced Ca2+ entry and Ca2+ release in human platelets. Biochimica et biophysica acta, 1992, Mar-02, Volume: 1104, Issue:2 Topics: Blood Platelets; Calcium; Calcium Channels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydropyridines; Fura-2; Humans; Indoles; Manganese; Platelet Activating Factor; Thrombin	1992
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats. European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2 Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles	1992
1,4-Dihydropyridines as antagonists of platelet activating factor. 1. Synthesis and structure-activity relationships of 2-(4-heterocyclyl)phenyl derivatives. Journal of medicinal chemistry, 1992, Aug-21, Volume: 35, Issue:17 Topics: Animals; Dihydropyridines; Dogs; Imidazoles; Mice; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship	1992
Lipase-catalyzed enantioselective hydrolysis of 4-alkyl-1,4-dihydropyridine derivatives: synthesis of (+)- and (-)-methyl 2-(phenylthio)ethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (PCA 4248). Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:4 Topics: Dihydropyridines; Hydrolysis; Lipase; Platelet Activating Factor; Stereoisomerism	1992
UK-74,505, a novel and selective PAF antagonist, exhibits potent and long lasting activity in vivo. Agents and actions. Supplements, 1991, Volume: 34 Topics: Animals; Blood Cells; Bronchoconstriction; Capillary Permeability; Cell Aggregation; Dihydropyridines; Dogs; Female; Guinea Pigs; Imidazoles; Male; Platelet Activating Factor; Pyridines; Rats; Rats, Inbred Strains; Time Factors	1991
Enterolobin induces rat paw oedema independently of PAF-acether. Memorias do Instituto Oswaldo Cruz, 1991, Volume: 86 Suppl 2 Topics: Animals; Azepines; Dihydropyridines; Diterpenes; Edema; Ginkgolides; Lactones; Male; Plant Proteins; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles	1991
1,4-Dihydropyridines, a new class of platelet-activating factor receptor antagonists: in vitro pharmacologic studies. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1 Topics: Animals; Blood Platelets; Dihydropyridines; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin	1990
Pharmacological actions of PCA 4248, a new platelet-activating factor receptor antagonist: in vivo studies. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1 Topics: Animals; Blood Pressure; Capillary Permeability; Dihydropyridines; Endotoxins; Male; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha	1990
4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists. Journal of medicinal chemistry, 1990, Volume: 33, Issue:12 Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Chemical Phenomena; Chemistry; Dihydropyridines; Heart Rate; Ileum; Male; Microsomes; Molecular Structure; Muscle Contraction; Myocardial Contraction; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1990
PCA-4248, a PAF receptor antagonist, inhibits PAF-induced phosphoinositide turnover. European journal of pharmacology, 1995, Aug-15, Volume: 290, Issue:3 Topics: Animals; Blood Platelets; Cell Membrane; Dihydropyridines; In Vitro Techniques; Kinetics; Phosphatidylinositols; Phosphorus Radioisotopes; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin	1995
Novel antagonists of platelet-activating factor. 2. Synthesis and structure-activity relationships of potent and long-acting heterofused [1,5]benzodiazepine and [1,4]diazepine derivatives of 2-methyl-1-phenylimidazo[4,5-c]pyridine. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Animals; Azepines; Benzene; Benzodiazepines; Dihydropyridines; Dogs; Imidazoles; In Vitro Techniques; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Rabbits; Structure-Activity Relationship; X-Ray Diffraction	1995
Compound PCA-4248 interferes with bronchopulmonary anaphylaxis and with in vitro hyperresponsiveness to platelet-activating factor. European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1 Topics: Anaphylaxis; Animals; Blood Cell Count; Bronchial Hyperreactivity; Bronchoconstriction; Dihydropyridines; Female; Guinea Pigs; Histamine Release; Immunization; In Vitro Techniques; Injections, Intravenous; Lung; Male; Platelet Activating Factor; Radioimmunoassay; Thromboxane B2	1993
[Pharmacological profile of F-0401, a novel dihydropyridine derivative. III. The anti-aggregatory action of F-0401 on rabbit platelets]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1995, Volume: 115, Issue:1 Topics: Animals; Cells, Cultured; Dihydropyridines; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Thromboxane A2	1995
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor. Blood, 1995, May-01, Volume: 85, Issue:9 Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles	1995
Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity. Journal of lipid mediators and cell signalling, 1994, Volume: 10, Issue:3 Topics: Administration, Oral; Animals; Aorta; Azepines; Blood Platelets; Brain; Calcium Channels, L-Type; Capillary Permeability; Cattle; Dihydropyridines; Diltiazem; Gallopamil; Guinea Pigs; Hypotension; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle Proteins; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Rabbits; Rats; Rats, Sprague-Dawley; Skin; Triazoles; Tritium	1994
IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody. Journal of immunology (Baltimore, Md. : 1950), 1995, Feb-01, Volume: 154, Issue:3 Topics: Animals; Antibodies, Monoclonal; Calcium; Chemotaxis, Leukocyte; Dactinomycin; Dihydropyridines; Edema; Eosinophils; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Skin	1995
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin. British journal of pharmacology, 1994, Volume: 113, Issue:2 Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan	1994
Dissociation between secretion and protein phosphorylation in agonist-stimulated platelets; action of PCA-4230, a new antithrombotic drug. Thrombosis research, 1994, Jul-15, Volume: 75, Issue:2 Topics: Animals; Blood Platelets; Blood Proteins; Calcimycin; Cytoplasmic Granules; Dihydropyridines; Fibrinolytic Agents; Phosphorylation; Platelet Activating Factor; Rabbits; Thrombin	1994
Platelet-activating factor inhibits (Na+,K+) ATPase activity in rat brain. Neuroscience research, 1994, Volume: 19, Issue:2 Topics: Animals; Brain; Calcium; Dihydropyridines; Egtazic Acid; In Vitro Techniques; Male; Platelet Activating Factor; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	1994
Lipopolysaccharide-induced pleural neutrophil accumulation depends on marrow neutrophils and platelet-activating factor. European journal of pharmacology, 1994, Apr-04, Volume: 270, Issue:2-3 Topics: Animals; Azepines; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cell Movement; Dihydropyridines; Escherichia coli; Injections; Kinetics; Leukocyte Count; Lipopolysaccharides; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleura; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thorax; Triazoles	1994
Interference of PCA 4248, a novel PAF receptor antagonist, with antigen-induced paw edema in mice. European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2 Topics: Animals; Dihydropyridines; Edema; Injections, Intraperitoneal; Male; Mice; Ovalbumin; Platelet Activating Factor	1993
PAF and thrombin actions in platelets are selectively affected by a new 1,4-dihydropyridine derivative. Journal of biochemistry, 1993, Volume: 113, Issue:4 Topics: Animals; Arachidonic Acid; Blood Platelets; Diglycerides; Dihydropyridines; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Type C Phospholipases	1993
Interference of the PAF receptor antagonist, PCA 4248, with the rat pleurisy evoked by inflammatory mediators or allergen. European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1 Topics: Allergens; Animals; Bradykinin; Dihydropyridines; Edema; Eosinophils; Exudates and Transudates; Female; Histamine; Hypersensitivity; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin	1993
Role of platelet-activating factor (PAF) in platelet accumulation in rabbit skin: effect of the novel long-acting PAF antagonist, UK-74,505. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: Animals; Arthus Reaction; Blood Platelets; Calcium; Dihydropyridines; Edema; Fura-2; Imidazoles; In Vitro Techniques; Indium Radioisotopes; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin; Skin; Zymosan	1993
Nitric oxide mediates the PAF-stimulated cyclic GMP production in hippocampal slices. Biochemical and biophysical research communications, 1996, Sep-04, Volume: 226, Issue:1 Topics: Animals; Arginine; Cyclic GMP; Dihydropyridines; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar	1996
Demonstration of reversible priming of human neutrophils using platelet-activating factor. Blood, 1996, Dec-01, Volume: 88, Issue:11 Topics: Adult; Azepines; Cell Adhesion; Cell Polarity; Cell Size; Cells, Cultured; Dihydropyridines; Enzyme Activation; Humans; Imidazoles; Macrophage-1 Antigen; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Superoxides; Time Factors; Triazoles; Tumor Necrosis Factor-alpha	1996
Different classes of PAF-antagonists block norepinephrine-induced vascular escape and tachyphylaxis in the isolated rabbit kidney. Research communications in molecular pathology and pharmacology, 1996, Volume: 94, Issue:2 Topics: Animals; Azepines; Dihydropyridines; Ginkgolides; In Vitro Techniques; Kidney; Lactones; Norepinephrine; Platelet Activating Factor; Rabbits; Tachyphylaxis; Triazoles; Vasoconstriction	1996
Comparison of the reversed passive Arthus and local Shwartzman reactions of rabbit skin: effects of the long-acting PAF antagonist UK-74,505. British journal of pharmacology, 1997, Volume: 120, Issue:7 Topics: Animals; Arthus Reaction; Cell Aggregation; Dihydropyridines; Imidazoles; Neutrophils; Platelet Activating Factor; Rabbits; Shwartzman Phenomenon	1997
Platelet-activating factor plays a pivotal role in the induction of experimental lung injury. American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:2 Topics: Animals; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Elapid Venoms; Extravascular Lung Water; Female; Humans; Imidazoles; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Serum Albumin; Skin; Zymosan	1998
A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligaton and puncture sepsis. Shock (Augusta, Ga.), 2003, Volume: 19, Issue:1 Topics: Animals; Cecum; Cell Movement; Dihydropyridines; Eicosanoids; Imidazoles; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peritoneum; Platelet Activating Factor; Prostaglandins; Time Factors; Wounds, Penetrating	2003
Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatment. British journal of pharmacology, 2003, Volume: 139, Issue:4 Topics: Animals; Dihydropyridines; Disease Models, Animal; Imidazoles; Intestinal Diseases; Intestines; Lung Diseases; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reperfusion Injury	2003
Sponge-induced angiogenesis and inflammation in PAF receptor-deficient mice (PAFR-KO). British journal of pharmacology, 2004, Volume: 141, Issue:7 Topics: Acetylglucosaminidase; Administration, Topical; Animals; Blood Vessels; Chemokines; Dihydropyridines; Fibroblasts; Granulation Tissue; Granuloma; Hemoglobins; Imidazoles; Implants, Experimental; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Knockout; Neovascularization, Pathologic; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Polyurethanes; Porifera; Receptors, G-Protein-Coupled; Skin	2004
Microglial calcium responses to platelet-activating factor are inhibited by analogue CAS 99103-16-9 and dihydropyridine PCA 4248 but not by ginkgolide A. Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:2 Topics: Aniline Compounds; Calcium; Calcium Signaling; Cell Line; Dihydropyridines; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Microglia; Platelet Activating Factor; United Kingdom; Xanthenes	2004
Synergistic effect of platelet-activating factor and tumor necrosis factor-alpha on corneal myofibroblast apoptosis. Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Cell Membrane; Cells, Cultured; Cornea; Cytoplasm; Dihydropyridines; Drug Combinations; Drug Synergism; Fibroblasts; Fluorescent Antibody Technique, Indirect; In Situ Nick-End Labeling; Microscopy, Fluorescence; Nuclear Envelope; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Swine; Tumor Necrosis Factor-alpha	2006
A role for inflammatory mediators in the induction of immunoregulatory B cells. Journal of immunology (Baltimore, Md. : 1950), 2006, Oct-01, Volume: 177, Issue:7 Topics: Adoptive Transfer; Animals; Antigens, CD19; B-Lymphocytes; Dermatitis, Contact; Dihydropyridines; Flow Cytometry; Fluorescein-5-isothiocyanate; Immune Tolerance; Inflammation; Interleukin-10; Leukocyte Common Antigens; Lymphocyte Activation; Mice; Mice, Mutant Strains; Platelet Activating Factor; Serotonin; Serotonin Antagonists; Ultraviolet Rays	2006
Autocrine activation of ion currents in the two-cell mouse embryo. Experimental cell research, 2007, Aug-01, Volume: 313, Issue:13 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Autocrine Communication; Blastocyst; Calcium; Calcium Channel Blockers; Chorionic Gonadotropin; Dihydropyridines; Embryo, Mammalian; Female; Ion Transport; Membrane Potentials; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Zygote	2007
Synergism in the repression of COX-2- and TNFalpha-induction in platelet activating factor-stressed human neural cells. Neuroscience letters, 2007, Oct-09, Volume: 426, Issue:1 Topics: Anti-Inflammatory Agents; Budesonide; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Cyclooxygenase 2; Dihydropyridines; Dinoprostone; Drug Synergism; Encephalitis; Gene Expression; Humans; Neurons; Oxidative Stress; Platelet Activating Factor; Signal Transduction; Stress, Physiological; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation	2007
Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats. Immunology, 2008, Volume: 124, Issue:3 Topics: Animals; Benzopyrans; Carboxylic Acids; Dermatitis; Dihydropyridines; Imidazoles; Leukotriene B4; Male; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Skin; Thiazoles	2008
LAU-0901, a novel platelet-activating factor antagonist, is highly neuroprotective in cerebral ischemia. Experimental neurology, 2008, Volume: 214, Issue:2 Topics: Acute Disease; Animals; Behavior, Animal; Brain Ischemia; Cerebrovascular Circulation; Dihydropyridines; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neocortex; Neuroprotective Agents; Platelet Activating Factor; Rats; Rats, Sprague-Dawley	2008
Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:2 Topics: Animals; Azepines; Cell Movement; Dihydropyridines; Female; Flagellin; Humans; Imidazoles; Leukotriene B4; Ligands; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Poly I-C; Propionates; Quinolines; Thienopyridines; Toll-Like Receptors; Triazoles	2010
The induction of an angiogenic response in corneal myofibroblasts by platelet-activating factor (PAF). Current eye research, 2010, Volume: 35, Issue:12 Topics: Animals; Cells, Cultured; Coculture Techniques; Cornea; Corneal Neovascularization; Dihydropyridines; Endothelial Cells; Gene Expression Regulation; Humans; Myofibroblasts; Platelet Activating Factor; Rabbits; Thrombospondin 1; Umbilical Veins; Vascular Endothelial Growth Factor A	2010
Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice. PLoS pathogens, 2010, Nov-04, Volume: 6, Issue:11 Topics: Animals; Apoptosis; Blotting, Western; Chickens; Dihydropyridines; Disease Models, Animal; Inflammation Mediators; Influenza A Virus, H1N1 Subtype; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orthomyxoviridae Infections; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Toll-Like Receptors; Viral Load	2010
Platelet-activating factor receptor antagonism targets neuroinflammation in experimental epilepsy. Epilepsia, 2011, Volume: 52, Issue:3 Topics: Animals; Cell Death; Cytokines; Dihydropyridines; Dinoprostone; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, G-Protein-Coupled	2011
Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice. The American journal of pathology, 2011, Volume: 178, Issue:2 Topics: Animals; Cytokines; Dihydropyridines; Disease Progression; Down-Regulation; Humans; Mice; Mice, Transgenic; Phenotype; Platelet Activating Factor; Platelet Membrane Glycoproteins; Psoriasis; PUVA Therapy; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Skin; STAT3 Transcription Factor; Th17 Cells; Transforming Growth Factor beta1; Up-Regulation	2011
Lipoxin A₄ inhibits platelet-activating factor inflammatory response and stimulates corneal wound healing of injuries that compromise the stroma. Experimental eye research, 2012, Volume: 103 Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CXCL1; Corneal Stroma; Dihydropyridines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Injuries; Fibronectins; Fluorescent Antibody Technique, Indirect; Interleukin-1alpha; Lipoxins; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Wound Healing	2012
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:1 Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan	2013
Platelet-activating factor increases reactive oxygen species-mediated microbicidal activity of human macrophages infected with Leishmania (Viannia) braziliensis. Pathogens and disease, 2017, 09-29, Volume: 75, Issue:7 Topics: Acetophenones; Dihydropyridines; Enzyme Inhibitors; Gene Expression; Humans; Leishmania braziliensis; Macrophages; NADPH Oxidases; Phagocytosis; Platelet Activating Factor; Primary Cell Culture; Reactive Oxygen Species; Respiratory Burst	2017