Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cyclic gmp

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with cyclic gmp in 48 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(cyclic gmp)
Trials
(cyclic gmp)
Recent Studies (post-2010) (cyclic gmp)
9,15618755222,3463334,062

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19909 (18.75)18.7374
1990's26 (54.17)18.2507
2000's13 (27.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Till, U1
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S1
Ciapa, B; Randriamampita, C; Trautmann, A1
Drummer, C; Gerzer, R; Heim, JM; Karrenbrock, B; Valta-Seufzer, U1
Haslam, RJ; Maurice, DH1
Dickinson, KE; Hirschowitz, BI; Hokin, LE; Pruitt, RE; Sekar, MC1
Drummer, C; Gerzer, R; Heim, JM; Karrenbrock, B1
Auguet, M; Baranes, J; Braquet, P; Guillon, JM; Hellegouarch, A; Pirotzky, E1
Behrens, T; Goodwin, JS1
Hackenthal, E; Taugner, R1
Armstrong, RA; Jones, RL; Wilson, NH1
Loeb, AL; Peach, MJ; Singer, HA1
Bushfield, M; MacIntyre, DE; Shaw, AM1
Rink, TJ1
Alonso, F; Mato, JM; Sánchez-Crespo, M1
Alessio, P; Bussolino, F; Calvino, R; Fruttero, R; Gasco, A; Ghigo, D; Heller, R; Pescarmona, G; Till, U; Todde, R1
Alkon, DL; Inoue, H; Kouchi, T; Sakakibara, M; Yoshioka, T1
Bailly, C; Imbert-Teboul, M; Néant, F1
Anderson, DC; Granger, DN; Kubes, P; Kurose, I; Miyasaka, M; Paulson, J; Wolf, R1
Bosia, A; Bussolino, F; Calvino, R; Gasco, A; Ghigo, D; Heller, R; Pescarmona, GP; Till, U1
Alberola, ML; Caramelo, C; Casado, S; Esteban, A; López-Farré, A; Millás, I; Montón, M1
Emeis, JJ; Tranquille, N1
Karlsson, JA; Raeburn, D1
Bozzaro, S; Bussolino, F; Cristino, E; Sordano, C; Wurster, B1
Befus, AD; Hogaboam, CM; Wallace, JL1
Howard, KM; Mustafa, SB; Olson, MS1
Kamata, K; Kasuya, Y; Numazawa, T1
Hirafuji, M; Minami, M; Nezu, A; Shinoda, H1
Bergamaschi, M; Bongrani, S; Caruso, P; Civelli, M; Gasco, A; Giossi, M; Razzetti, R1
Calcerrada, MC; Catalán, RE; Hernández, F; Martínez, AM; Pérez, MJ1
Barkin, M; Barnett, CC; Moore, EE; Offner, PJ; Partrick, DA; Silliman, CC1
Alves, AC; Cordeiro, RS; e Silva, PM; Lagente, V; Martins, MA; Pires, AL1
Calcerrada, MC; Catalán, RE; Martínez, AM1
Boronkay, E; Gyürky, J; Herbert, JM; Kapui, Z; Mikus, EG; Pascal, M; Schaeffer, P1
Fox-Robichaud, A; Kubes, P; Payne, D1
Fukuda, S; Predescu, DN; Schmid-Schönbein, GW; Yasu, T1
Chen, JS; Chen, LW; Shen, AY; Wu, SN1
Ko, FN; Liao, CH; Teng, CM; Wu, CL1
Kelly, RF1
Murota, M; Sakai, H; Suzuki, T; Takahashi, Y; Takeguchi, N1
Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG1
Bussolati, B; Camussi, G; Mariano, F; Migliori, M; Russo, S; Triolo, G1
Bredt, DS; Hua, Z; Johns, RA; Tao, YX; Xu, Y; Zhang, B1
Ameer, A; Ibe, BO; Portugal, AM; Raj, JU; Renteria, L1
Andersson, J; Bengtsson, T; Grenegård, M; Kälvegren, H1
Eckert, RE; Jones, SL1
Dohi, T; Kitayama, T; Morioka, N; Morita, K1
Chin, TK; Hofmann, PA; Leary, PJ; Morrison, RR; Rajasekaran, S; Tuomanen, EI1

Reviews

3 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cyclic gmp

ArticleYear
Hormonal signals and intracellular messengers for renin secretion.
    Molecular and cellular endocrinology, 1986, Volume: 47, Issue:1-2

    Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cyclic AMP; Cyclic GMP; Dopamine; Epinephrine; Histamine; Hormones; Nerve Tissue Proteins; Neuropeptide Y; Norepinephrine; Platelet Activating Factor; Prostaglandins; Renin; Vasopressins

1986
Stimulus-response coupling mechanisms in human platelets.
    Agents and actions. Supplements, 1986, Volume: 20

    Topics: Blood Platelets; Calcium; Cell Membrane Permeability; Contractile Proteins; Cyclic AMP; Cyclic GMP; Diglycerides; Humans; Hydrogen-Ion Concentration; Inositol Phosphates; Physical Stimulation; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; Stimulation, Chemical; Thromboxanes; Transduction, Genetic

1986
Current strategies in lung preservation.
    The Journal of laboratory and clinical medicine, 2000, Volume: 136, Issue:6

    Topics: Animals; Antioxidants; Cold Temperature; Cyclic AMP; Cyclic GMP; Free Radical Scavengers; History, 20th Century; Humans; Lung; Lung Injury; Lung Transplantation; Organ Preservation; Platelet Activating Factor; Reperfusion Injury; Respiration, Artificial; Solutions; Vasodilator Agents

2000

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cyclic gmp

ArticleYear
Comparison of anti-platelet properties of molsidomine, isosorbide-5-mononitrate and placebo in healthy volunteers.
    European heart journal, 1991, Volume: 12, Issue:4

    Topics: Adult; Bleeding Time; Cyclic GMP; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Molsidomine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Reference Values; Thromboxane B2

1991

Other Studies

44 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cyclic gmp

ArticleYear
Nitrovasodilators inhibit thrombin-induced platelet-activating factor synthesis in human endothelial cells.
    Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2

    Topics: Acetyltransferases; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Humans; Molsidomine; Nitroprusside; Platelet Activating Factor; Thrombin

1992
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar

1992
Cyclic-GMP-dependent refilling of calcium stores in macrophages.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 417, Issue:6

    Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Biological Transport; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cyclic GMP; Cytophotometry; Macrophages; Mice; Platelet Activating Factor; SRS-A

1991
Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP.
    Molecular pharmacology, 1990, Volume: 37, Issue:5

    Topics: Adenosine; Adenylyl Cyclases; Alprostadil; Animals; Blood Platelets; Cyclic AMP; Cyclic GMP; Enzyme Activation; Ferricyanides; Hemoglobins; In Vitro Techniques; Kinetics; Molsidomine; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinolones; Rabbits; Radioimmunoassay; Vasodilator Agents

1990
Muscarinic receptor antagonist activity of diacylglycerol lipase and kinase inhibitors.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Brain; Cells, Cultured; Cyclic GMP; Cyclohexanes; Cyclohexanones; Guinea Pigs; Heart; Lipoprotein Lipase; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Platelet Activating Factor; Pyrimidinones; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiazoles; Tritium

1990
Inhibition of platelet activating factor-induced platelet aggregation by molsidomine, SIN-1, and nitrates in vitro and ex vivo.
    Journal of cardiovascular pharmacology, 1989, Volume: 14 Suppl 11

    Topics: Cyclic GMP; Enzyme Activation; In Vitro Techniques; Molsidomine; Nitrates; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents

1989
Lack of effect of atrial natriuretic factor on the tone induced in rat portal vein by platelet-activating factor.
    European journal of pharmacology, 1988, Jan-12, Volume: 145, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Bucladesine; Cyclic GMP; In Vitro Techniques; Male; Muscle Tonus; Nitroprusside; Platelet Activating Factor; Portal Vein; Rats

1988
Role of lipoxygenase metabolites of arachidonic acid in T cell activation.
    Annals of the New York Academy of Sciences, 1988, Volume: 524

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclic GMP; Humans; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lipoxygenase; Lymphocyte Activation; Mice; Platelet Activating Factor; T-Lymphocytes

1988
Mechanism of the inhibition of platelet aggregation produced by prostaglandin F2 alpha.
    Prostaglandins, 1985, Volume: 29, Issue:4

    Topics: Adenosine Diphosphate; Aspirin; Cyclic AMP; Cyclic GMP; Dinoprost; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins F; Prostaglandins H; Prostaglandins, Synthetic; Thrombin

1985
Mechanisms of endothelium-dependent vascular smooth muscle relaxation.
    Biochemical pharmacology, 1985, Jun-01, Volume: 34, Issue:11

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Activating Factor; Receptors, Muscarinic; Vasoconstriction; Vasodilation; Vasodilator Agents

1985
Regulation of platelet cytosolic free calcium by cyclic nucleotides and protein kinase C.
    FEBS letters, 1985, Sep-02, Volume: 188, Issue:2

    Topics: Aminoquinolines; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Diglycerides; Fluorescent Dyes; Humans; In Vitro Techniques; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Spectrometry, Fluorescence

1985
Modulatory role of cyclic AMP in the release of platelet-activating factor from human polymorphonuclear leucocytes.
    Immunology, 1982, Volume: 45, Issue:3

    Topics: Blood Coagulation Factors; Blood Platelets; Cyclic AMP; Cyclic GMP; Epinephrine; Glucuronidase; Humans; Isoproterenol; Lysophosphatidylcholines; Phosphodiesterase Inhibitors; Pilocarpine; Platelet Activating Factor; Platelet Aggregation; Zymosan

1982
S35b, a new phenylsulfonylfuroxan compound, inhibits thrombin-induced synthesis of platelet-activating factor and prostacyclin in human endothelial cells.
    Agents and actions, 1993, Volume: 40, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Iloprost; Oxadiazoles; Platelet Activating Factor; Platelet Aggregation Inhibitors; Thrombin; Umbilical Veins

1993
Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor.
    Biochemical and biophysical research communications, 1994, Jul-15, Volume: 202, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium Chloride; Models, Biological; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Photoreceptor Cells, Invertebrate; Platelet Activating Factor; Pyrimidinones; Snails; Spermine; Thiazoles; Thionucleotides; Type C Phospholipases

1994
Cyclic guanosine monophosphate is the mediator of platelet-activating factor inhibition on transport by the mouse kidney thick ascending limb.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoquinolines; Kidney Medulla; Kinetics; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Parathyroid Hormone; Platelet Activating Factor; Protein Kinase C; Time Factors; Vasopressins

1994
Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage.
    Circulation research, 1993, Volume: 73, Issue:1

    Topics: Albumins; Animals; Arginine; Azepines; Blood Flow Velocity; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cyclic GMP; Intercellular Adhesion Molecule-1; Leukocytes; Male; NG-Nitroarginine Methyl Ester; P-Selectin; Phalloidine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Triazoles; Venules

1993
Activation of endothelial guanylate cyclase inhibits cellular reactivity.
    Agents and actions. Supplements, 1995, Volume: 45

    Topics: Arachidonic Acid; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Guanylate Cyclase; Humans; Molsidomine; Nitric Oxide; Nitroprusside; Oxadiazoles; Platelet Activating Factor; Thrombin; Umbilical Veins

1995
Effects of aspirin on platelet-neutrophil interactions. Role of nitric oxide and endothelin-1.
    Circulation, 1995, Apr-01, Volume: 91, Issue:7

    Topics: Animals; Aspirin; Blood Platelets; Calcium; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Rabbits

1995
The role of cyclic nucleotides in the release of tissue-type plasminogen activator and von Willebrand factor.
    Thrombosis and haemostasis, 1993, Mar-01, Volume: 69, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Bradykinin; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Male; Nitroprusside; Platelet Activating Factor; Rats; Rats, Wistar; Secretory Rate; Tissue Plasminogen Activator; von Willebrand Factor

1993
Effects of isoenzyme-selective inhibitors of cyclic nucleotide phosphodiesterase on microvascular leak in guinea pig airways in vivo.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 3',5'-Cyclic-AMP Phosphodiesterases; Albuterol; Animals; Bronchi; Capillary Permeability; Cyclic AMP; Cyclic GMP; Guinea Pigs; Isoenzymes; Male; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Activating Factor; Trachea

1993
Platelet activating factor modulates signal transduction in Dictyostelium.
    Journal of cell science, 1993, Volume: 104 ( Pt 1)

    Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Nephelometry and Turbidimetry; Platelet Activating Factor; Signal Transduction; Stereoisomerism

1993
Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Oct-01, Volume: 151, Issue:7

    Topics: Animals; Cyclic GMP; Interleukin-1; Male; Mast Cells; Nitric Oxide; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Thrombin

1993
Platelet-activating factor augments lipopolysaccharide-induced nitric oxide formation by rat Kupffer cells.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:6

    Topics: Animals; Arginine; Biological Transport, Active; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Kinetics; Kupffer Cells; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Shock, Septic

1996
Mechanisms of desensitization of vasodilatation induced by platelet-activating factor in hypertensive rats.
    European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3

    Topics: Acetylcholine; Animals; Cyclic GMP; GTP-Binding Proteins; Hypertension; Hypertension, Renovascular; In Vitro Techniques; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Vasodilation; Virulence Factors, Bordetella

1996
Involvement of platelet cyclic GMP but not cyclic AMP suppression in leukocyte-dependent platelet adhesion to endothelial cells induced by platelet-activating factor in vitro.
    British journal of pharmacology, 1996, Volume: 117, Issue:2

    Topics: Animals; Blood Platelets; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Methylene Blue; Neutrophils; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Adhesiveness; Purinones; Rabbits

1996
The involvement of the release of nitric oxide in the pharmacological activity of the new furoxan derivative CHF 2363.
    British journal of pharmacology, 1996, Volume: 118, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Oxadiazoles; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Vasodilator Agents

1996
Nitric oxide mediates the PAF-stimulated cyclic GMP production in hippocampal slices.
    Biochemical and biophysical research communications, 1996, Sep-04, Volume: 226, Issue:1

    Topics: Animals; Arginine; Cyclic GMP; Dihydropyridines; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar

1996
Nitric oxide attenuates platelet-activating factor priming for elastase release in human neutrophils via a cyclic guanosine monophosphate-dependent pathway.
    Surgery, 1997, Volume: 122, Issue:2

    Topics: Adult; Analysis of Variance; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; In Vitro Techniques; Kinetics; Leukocyte Elastase; Models, Biological; Molsidomine; Neutrophils; Nitric Oxide; Platelet Activating Factor; Signal Transduction; Substrate Specificity

1997
Effect of selective phosphodiesterase inhibitors on the rat eosinophil chemotactic response in vitro.
    Memorias do Instituto Oswaldo Cruz, 1997, Volume: 92 Suppl 2

    Topics: Analysis of Variance; Animals; Cell Movement; Chemotactic Factors, Eosinophil; Cyclic AMP; Cyclic GMP; Eosinophils; Leukotriene B4; Phosphodiesterase Inhibitors; Platelet Activating Factor; Rats; Rats, Wistar

1997
Glutamate release is involved in PAF-increased cyclic GMP levels in hippocampus.
    Biochemistry and molecular biology international, 1999, Volume: 47, Issue:3

    Topics: Animals; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Male; Platelet Activating Factor; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Riluzole

1999
Experimental studies on guanosine 3',5'-cyclic monophosphate levels and airway responsiveness of the novel phosphodiesterase type 5 inhibitor SR 265579 in guinea-pigs.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:8

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoconstriction; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Epithelial Cells; Guinea Pigs; Histamine; In Vitro Techniques; Isoenzymes; Male; Muscle Tonus; Phosphodiesterase Inhibitors; Platelet Activating Factor; Respiratory System; Trachea

1999
Inhaled NO reaches distal vasculatures to inhibit endothelium- but not leukocyte-dependent cell adhesion.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Administration, Inhalation; Animals; Capillary Permeability; Cats; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Histamine; Hydrogen Peroxide; Leukocytes; Leukotriene B4; Lung; Microscopy, Video; Nitric Oxide; Oxadiazoles; Oxidants; Oxidative Stress; P-Selectin; Platelet Activating Factor; Quinoxalines

1999
Mechanisms for regulation of fluid shear stress response in circulating leukocytes.
    Circulation research, 2000, Jan-07, Volume: 86, Issue:1

    Topics: Aminoquinolines; Animals; Cell Adhesion; Cyclic GMP; Humans; In Vitro Techniques; Leukocytes; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activating Factor; Rats; Rats, Wistar; Stress, Physiological

2000
Differential regulation of Ca2+ influx by fMLP and PAF in human neutrophils: possible involvement of store-operated Ca2+ channel.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:3

    Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cyclic GMP; Egtazic Acid; Enzyme Activation; Humans; Imidazoles; Loperamide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate

2000
Antiplatelet effect of marchantinquinone, isolated from Reboulia hemisphaerica, in rabbit washed platelets.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Bibenzyls; Blood Platelets; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethers, Cyclic; Phosphatidylinositols; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane B2

2000
Nitric oxide-induced Cl- secretion in isolated rat colon is mediated by the release of thromboxane A2.
    The Journal of physiology, 2002, Aug-15, Volume: 543, Issue:Pt 1

    Topics: Animals; Camptothecin; Chlorides; Colon; Cyclic GMP; Enzyme Inhibitors; Female; Gene Expression; Imidazoles; Intestinal Mucosa; Irinotecan; Membrane Potentials; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Parasympathomimetics; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Thromboxane A2

2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2002
Platelet-activating factor synthesis by neutrophils, monocytes, and endothelial cells is modulated by nitric oxide production.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Adult; Arginine; Cells, Cultured; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Humans; Lipopolysaccharides; Monocytes; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Platelet Activating Factor; Stereoisomerism; Tumor Necrosis Factor-alpha

2003
Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.
    Experimental neurology, 2004, Volume: 189, Issue:1

    Topics: Animals; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Ginkgolides; Guanylate Kinases; Intracellular Signaling Peptides and Proteins; Lactones; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Activating Factor; Precipitin Tests; Propidium; Receptors, N-Methyl-D-Aspartate

2004
Platelet-activating factor modulates activity of cyclic nucleotides in fetal ovine pulmonary vascular smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Fetus; Inositol 1,4,5-Trisphosphate; Lung; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pregnancy; Receptors, G-Protein-Coupled; Sheep

2007
Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors.
    European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3

    Topics: Adenosine Triphosphate; Adult; Aspirin; Caffeic Acids; Cell Line, Tumor; Chlamydophila pneumoniae; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Flavanones; Humans; Lipoxygenase Inhibitors; Piroxicam; Platelet Activating Factor; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12

2007
Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant.
    Journal of leukocyte biology, 2007, Volume: 82, Issue:5

    Topics: Actins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Interleukin-8; Leukotriene B4; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Serine; Signal Transduction; Tumor Necrosis Factor-alpha

2007
Glycinergic mediation of tactile allodynia induced by platelet-activating factor (PAF) through glutamate-NO-cyclic GMP signalling in spinal cord in mice.
    Pain, 2008, Sep-15, Volume: 138, Issue:3

    Topics: Animals; Cyclic GMP; Glutamic Acid; Male; Mice; Nitric Oxide; Pain; Pain Measurement; Platelet Activating Factor; Receptors, Glycine; Signal Transduction; Spinal Cord; Touch

2008
A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Animals; Calcium; Calcium Signaling; Cell Shape; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Ginkgolides; Lactones; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors; Ventricular Function, Left

2008