1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cv 6209

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with cv 6209 in 115 studies

Compound Research Comparison

Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)	Studies (cv 6209)	Trials (cv 6209)	Recent Studies (post-2010) (cv 6209)
9,156	187	552	133	0	2

Protein Interaction Comparison

Protein	Taxonomy	1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)	cv 6209 (IC50)
Platelet-activating factor receptor	Cavia porcellus (domestic guinea pig)		0.033

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (11.30)	18.7374
1990's	86 (74.78)	18.2507
2000's	15 (13.04)	29.6817
2010's	1 (0.87)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hirano, T; Manabe, T	1
Bates, EJ; Ferrante, A; Kowanko, IC	1
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S	1
Iwamoto, I; Matsumura, R; Nakajima, H; Takatsu, K; Tomioka, H; Tomoe, S; Yoshida, S	1
Inada, M; Iwasaka, T; Sugiura, T; Takayama, Y; Taniguchi, H	1
Mori, K; Nishizawa, F; Ozawa, K; Shimahara, Y; Takada, Y; Yamaguchi, T; Yamaoka, Y	1
Kondo, M; Naito, Y; Takahashi, S; Tanigawa, T; Ueda, S; Yoshida, N; Yoshikawa, T	1
Gotoh, M; Kanai, T; Monden, M; Mori, T; Nakano, H; Ukei, T; Umeshita, K; Wang, KS	1
Binnaka, T; Fujimura, K; Inoue, K; Kitagawa, S; Kubota, Y; Mizuno, T; Tani, K; Yamaguchi, T	1
Bates, EJ; Ferrante, A; Harvey, DP	1
Asaka, M; Entani, C; Fujita, M; Iida, H; Izumino, K; Sasayama, S; Takata, M	1
Imanishi, N; Morooka, S; Uchida, M	1
Fukumura, D; Imaeda, H; Kurose, I; Miura, S; Nagata, H; Sekizuka, E; Shiozaki, H; Suematsu, M; Tashiro, H; Tsuchiya, M	1
Lim, WH; Stewart, AG	1
Hu, WM; Man, RY	1
Harris, T; Stewart, AG	1
Kondo, M; Naito, Y; Takahashi, S; Tanigawa, T; Yoshida, N; Yoshikawa, T	1
Forn, J; García-Rafanell, J; Gómez, LA; Merlos, M; Vericat, L	1
Fukumura, D; Kurose, I; Miura, S; Nagata, H; Sekizuka, E; Suematsu, M; Tsuchiya, M	1
Imura, Y; Kawamura, M; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S	1
Bergström, M; Carlsson, J; Gáti, I; Långström, B; Muhr, C	1
Goto, T; Hibino, A; Mimura, K; Mori, Y; Mune, M; Nishikawa, O; Nomoto, H; Okada, K; Sonobe, M; Yukawa, S	1
Ehrlich, YH; Kornecki, E	1
Ikeda, I; Oda, M; Sakakura, M; Yasunaga, K	1
Hoshihara, Y; Miyamoto, T; Nogami, M; Shiga, J; Tabuchi, M; Tsubura, K; Yamamoto, T	1
Hayashi, M; Imai, Y; Oh-ishi, S	1
Imura, Y; Maezaki, N; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S	1
Bergström, M; Carlsson, J; Gáti, I; Muhr, C	1
Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB	1
Imanishi, M; Miura, K; Okumura, M; Shimmen, T; Yamamoto, K; Yamanaka, S; Yamashita, Y; Yukimura, T	1
Arita, Y; Furukawa, M; Kimura, T; Nawata, H; Sumii, T; Takano, S; Yamaguchi, H	1
Blumenthal, RN; Kirchhoff, CF; Leff, AR; Munoz, NM; Strek, ME	1
Inoue, Y; Kohno, S; Miyazaki, T; Yamaguchi, K	1
Ando, M; Matsuura, S; Suginami, H	1
Akutsu, I; Amagai, M; Fukuda, T; Makino, S; Motojima, S; Numao, T	1
Fukuoka, T	1
Aoki, S; Kurosawa, M; Tsukagoshi, H	1
Miyamoto, T; Nogami, M; Suko, M	1
Binnaka, T; Hirohara, J; Kubota, Y; Mizuno, T; Sameshima, Y; Yamaguchi, T	1
Midorikawa, Y; Ogata, H	1
Fukuoka, T; Hisanaga, M; Kanehiro, H; Matsumoto, M; Nakajima, Y; Nakano, H; Segawa, M; Wada, T	1
Kurihara, H; Masaki, T; Morita, T; Oh-hashi, Y; Sugiyama, T; Takaku, F; Yamashita, T; Yanagisawa, M; Yazaki, Y; Yoshizumi, M	1
Lefer, AM; Stahl, GL; Terashita, Z	2
Dhar, A; Morrison, WJ; Shukla, SD	1
Morrison, WJ; Shukla, SD	1
Hawley, SB; Nieves, AL; Spada, CS; Williams, LS; Woodward, DF	1
Stewart, AG	1
Kamata, K; Kasuya, Y; Mori, T; Shigenobu, K	1
Kondo, K; Takayasu, M; Terao, S	1
Imura, Y; Iwasaki, K; Nishikawa, K; Shibouta, Y; Terashita, Z	1
Imura, Y; Nishikawa, K; Takatani, M; Tasaka, A; Terashita, Z; Tsushima, S; Yoshioka, Y	1
Bitterman, H; Lefer, AM; Stahl, GL; Terashita, Z	1
Fukuoka, T; Matsumoto, M; Nakajima, Y; Nakano, H; Shiratori, T	1
Imura, Y; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S	1
Fukumura, D; Ishii, H; Kimura, H; Kurose, I; Miura, S; Morishita, T; Nagata, H; Suzuki, M; Tsuchiya, M	1
Iwamoto, I; Tomioka, H; Tomoe, S; Yoshida, S	1
Iwamoto, I; Tomoe, S; Yoshida, S	1
Nieves, AL; Spada, CS; Tuckett, RP; Williams, LS; Woodward, DF	1
Arai, Y; Kamata, K; Kasuya, Y	1
Chiyotani, A; Isono, K; Kondo, M; Konno, K; Ozawa, Y; Takeuchi, S; Tamaoki, J	1
Kumagai, H; Nakayama, R; Saito, K	1
Fukutomi, M; Kawachi, K; Kitamura, S; Taniguchi, S; Yoshida, Y	1
Fukumura, D; Kai, A; Kudoh, Y; Kurose, I; Miura, S; Suematsu, M; Suzuki, H; Tashiro, H; Tsuchiya, M; Yoshioka, M	1
Altavilla, D; Bussolino, F; Calapai, G; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Saitta, A; Squadrito, F; Zingarelli, B	1
Gupta, JB; Kalra, J; Prasad, K; Prasad, M	1
Aosaki, N; Minezaki, K; Nakamura, H; Nakazawa, H; Ohsuzu, F; Senoh, M; Tuji, C	1
Inoue, K; Kitajima, T; Kubota, Y; Okuhira, M; Tani, K; Yamada, H; Yamaguchi, T	1
Gotoh, M; Kanai, T; Monden, M; Mori, T; Ukei, T; Umeshita, K; Wang, KS	1
Ikeda, M; Komatz, Y; Muguruma, K; Saito, K; Sugimoto, T	1
Endo, S; Hirashima, Y; Karasawa, K; Nojima, S; Otsuji, T; Takaku, A	1
Aomatsu, Y; Fukuoka, T; Horikawa, M; Ko, S; Nakajima, Y; Nakano, H; Ueno, M; Yoshimura, A	1
Fukumura, D; Imaeda, H; Kurose, I; Miura, S; Sekizuka, E; Serizawa, H; Shiozaki, H; Suematsu, M; Tashiro, H; Tsuchiya, M	1
Goto, Y; Hayashi, K; Mori, T; Nishi, O; Tominaga, T	1
Fukumura, D; Ishii, H; Kurose, I; Miura, S; Tsuchiya, M	1
Inoue, K; Kubota, Y; Ogura, M	1
Kamata, K; Kasuya, Y; Numazawa, T	1
Feinmark, SJ; Guo, SD; Hoffman, BF	2
Enzan, K; Inaba, H; Kurosawa, S; Yoshioka, N	1
Igarashi, Y; Kurosawa, M; Miyachi, Y; Tsukagoshi, H	1
Hamada, M; Hiroshiba, N; Honda, Y; Miyamoto, K; Nishiwaki, H; Ogura, Y	1
Endo, S; Hirashima, Y; Nogami, K; Takaku, A	1
Martin, SL; Morse, DS; Stahl, GL	1
Imagawa, M; Mimata, H; Nakagawa, M; Nomura, Y; Ogata, J; Takahashi, S	1
Cromie, WJ; Leff, AR; Palmer, JS; Plzak, LF	1
Friedman, E; Shi, LC; Wang, HY	1
English, JC; Feeley, EJ; Nikbakht-Sangari, M; Poostizadeh, A; Qayumi, KA	1
Ichinowatari, G; Ohuchi, K; Tanimoto, A; Yaginuma, H; Yamada, M	2
Francescangeli, E; Goracci, G; Grassi, S; Pettorossi, VE	1
Enzan, K; Mitsuhata, H; Shouji, K; Yoshioka, N	1
Kitamura, M; Minamiya, Y; Ogawa, J; Saito, S; Tozawa, K	1
Harada, M; Kimura, S; Nagata, M; Takeuchi, M; Watanabe, A	1
Gillespie, K; Jamieson, WR; Marier, JR; McGibbon, R; Mickleson, H; Sadeghi, H; Zhang, J	1
Bartemes, KR; Gleich, GJ; Kita, H; McKinney, S	1
Kotani, Y; Nishimura, Y; Shan, L; Yokoyama, M	1
Albini, A; Biancone, L; Boccellino, M; Bussolati, B; Camussi, G; Cantaluppi, V; Conaldi, PG; Del Sorbo, L; Toniolo, A	1
Bulkley, GB; Fuh, KC; Klein, AS; Maemura, K; Meneshian, A; Owaki, T; Takao, S; Wang, D	1
Goldman, R; Moshonov, S; Zor, U	1
Akutsu, A; Hayakawa, S; Hirano, H; Imai, T; Ishii, K; Nakahara, T; Shigenobu, K; Tanaka, H; Tanaka, Y	1
Fietzner, K; Fink, L; Grimminger, F; Hattar, K; Himmel, B; Seeger, W; Sibelius, U	1
Ibe, BO; Raj, JU	1
Gokorsch, S; Grimminger, F; Krüll, M; Lohmeyer, J; Mayer, K; Merfels, M; Muhly-Reinholz, M; Rosseau, S; Schwarzer, N; Seeger, W; Suttorp, N	1
Lee, RK; Teather, LA; Wurtman, RJ	1
Choi, EK; Choi, IW; Choi, JH; Han, SJ; Im, SY; Ko, HM; Lee, HK; Lee, HS; Seo, KH	1
Houghton, TJ; Lambertino, AT; Leff, AR; McGilvra, JD; Rawal, VH; Xu, C; Zhu, X	1
Aikawa, T; Hirose, T; Matsumoto, I; Shimada, T	1
Arthur, JR; McLeod, E; Sneddon, AA; Wahle, KW	1
Ahmed, AK; Aosai, F; Fang, H; Furuya, M; Mun, HS; Norose, K; Yano, A	1
Dessaint, JP; Devos, P; Dussart, P; Dutoit, V; El Behi, M; Lefranc, D; Prin, L; Vermersch, P; Zéphir, H	1
Day, JR; Ghimire, G; Leong, HS; Mahesh, BM; McCormack, AD; Podor, TJ; Rose, ML; Smith, JD	1
Cui, S; Kurata, Y; Liu, W; Shibamoto, T; Takano, H; Zhang, W	1
Boon, L; Galli, SJ; Mantegazza, R; Musio, S; Ohtsu, H; Pedotti, P; Pedotti, R; Steinman, L	1
Kuda, Y; Kurata, Y; Shibamoto, T; Tanida, M; Wang, M	1

Other Studies

115 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cv 6209

Article	Year
"Cocktail" therapy for acute pancreatitis: combined therapy of protease inhibitor, xanthine oxidase inhibitor and platelet activating factor antagonist in rat caerulein-induced pancreatis. Nihon geka hokan. Archiv fur japanische Chirurgie, 1992, Nov-01, Volume: 61, Issue:6 Topics: Acute Disease; Allopurinol; Animals; Ceruletide; Drug Therapy, Combination; Gabexate; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Xanthine Oxidase	1992
Platelet-activating factor inhibits proteoglycan synthesis and enhances neutrophil-mediated proteoglycan degradation in cartilage explants. Arthritis and rheumatism, 1992, Volume: 35, Issue:8 Topics: Animals; Azepines; Cartilage, Articular; Cattle; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteoglycans; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfur Radioisotopes; Triazoles; Tumor Necrosis Factor-alpha	1992
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta. British journal of pharmacology, 1992, Volume: 107, Issue:1 Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar	1992
CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. The American review of respiratory disease, 1992, Volume: 146, Issue:2 Topics: Administration, Inhalation; Animals; Antibodies, Monoclonal; CD4-Positive T-Lymphocytes; Cromolyn Sodium; Eosinophils; Evaluation Studies as Topic; Hypersensitivity, Delayed; Injections, Intraperitoneal; Interleukin-5; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Pyridinium Compounds; T-Lymphocytes, Regulatory; Trachea	1992
Role of platelet-activating factor in pulmonary edema after coronary ligation in dogs. Chest, 1992, Volume: 102, Issue:4 Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Extravascular Lung Water; Hemodynamics; Ligation; Myocardial Infarction; Platelet Activating Factor; Pulmonary Edema; Pyridinium Compounds	1992
Protective effect of platelet-activating factor antagonist on hepatic energy metabolism following transient hepatic inflow occlusion in rabbits. Circulatory shock, 1992, Volume: 38, Issue:2 Topics: Animals; Disease Models, Animal; Energy Metabolism; Ischemia; Ketone Bodies; Lactates; Liver; Male; Mitochondria, Liver; Platelet Activating Factor; Portal System; Pyridinium Compounds; Rabbits	1992
Effects of a platelet-activating factor antagonist, CV-6209, on gastric mucosal lesions induced by ischemia-reperfusion. Lipids, 1992, Volume: 27, Issue:12 Topics: Animals; Gastric Mucosa; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Vitamin E	1992
Protective effects of a PAF antagonist against liver injury induced by warm ischemia or cold preservation. Transplantation proceedings, 1992, Volume: 24, Issue:4 Topics: Animals; Bile; Ischemia; Liver Transplantation; Organ Preservation; Perfusion; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Temperature	1992
Burn-induced gastric mucosal hemodynamic disturbance in the rat. Role of platelet-activating factor. Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:2 Topics: Animals; Azepines; Blood Pressure; Burns; Gastric Mucosa; Hemodynamics; Hemoglobins; Male; Oxygen; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Regional Blood Flow; Thiazoles; Thiazolidines; Triazoles	1992
Inhibition of neutrophil respiratory burst and degranulation responses to platelet-activating factor by antagonists WEB 2086, CV 6209 and CV 3988. International archives of allergy and immunology, 1992, Volume: 97, Issue:1 Topics: Azepines; Cell Degranulation; Cell Survival; Humans; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Respiratory Burst; Triazoles	1992
Effects of the platelet-activating factor antagonists CV-6209 and CV-3988 on nephrotoxic serum nephritis in the rat. Nephron, 1992, Volume: 60, Issue:4 Topics: Animals; Anions; Basement Membrane; Binding Sites; Kidney Glomerulus; Male; Nephritis; Phospholipid Ethers; Platelet Activating Factor; Proteinuria; Pyridinium Compounds; Rats; Rats, Inbred Strains	1992
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine. British journal of pharmacology, 1992, Volume: 105, Issue:3 Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines	1992
Role of platelet activating factor on the fibrinolytic activation in the pathogenesis of gastric mucosal damage induced by endothelin-1. Gut, 1992, Volume: 33, Issue:7 Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Fibrinolysis; Gastric Mucosa; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Time Factors; Tissue Plasminogen Activator	1992
Regulation of eicosanoid generation in activated macrophages. International archives of allergy and applied immunology, 1991, Volume: 95, Issue:1 Topics: Animals; Azepines; Dexamethasone; Epoprostenol; Macrophage Activation; Macrophages; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles	1991
Differential actions of platelet-activating factor (PAF) receptor antagonists on the vasodilator and vasoconstrictor effects of PAF in the rat perfused heart. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Animals; Azepines; Coronary Vessels; Heart; In Vitro Techniques; Indoles; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Vasoconstriction; Vasodilation	1991
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles	1991
Role of platelet-activating factor (PAF) in superoxide production by human polymorphonuclear leukocytes. Lipids, 1991, Volume: 26, Issue:12 Topics: Calcimycin; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Superoxides	1991
Comparative study of the effect of CV-6209, a specific PAF-antagonist, on rat paw edema caused by different phlogogen agents. Pharmacology, 1990, Volume: 40, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Carrageenan; Dextrans; Edema; Histamine Antagonists; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Serotonin Antagonists; Zymosan	1990
Involvement of platelet-activating factor in endothelin-induced vascular smooth muscle cell contraction. Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 7 Topics: Animals; Calcium; Cell Line; Endothelins; Fura-2; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasoconstriction	1991
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: Anaphylaxis; Animals; Azepines; Furans; Hemolysis; Humans; Hypotension; Isoquinolines; Male; Microsomes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Tetrahydroisoquinolines; Triazoles	1992
Application of (methyl-11C)-methionine in the multicellular spheroid system. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:12 Topics: Benzeneacetamides; Benzoquinones; Carbon Radioisotopes; Cell Aggregation; Cell Line; Cycloheximide; Humans; Hydroxamic Acids; In Vitro Techniques; Lipoxygenase Inhibitors; Methionine; Platelet Activating Factor; Pyridinium Compounds; Tumor Cells, Cultured	1991
Effect of platelet-activating factor on lipoprotein lipase and blood lipids. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Cholesterol; Kinetics; Lipase; Lipids; Lipolysis; Lipoprotein Lipase; Male; Phospholipids; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Reference Values; Triglycerides	1991
Calcium ion mobilization in neuronal cells induced by PAF. Lipids, 1991, Volume: 26, Issue:12 Topics: Adenosine Triphosphate; Animals; Brain; Calcium; Cell Line; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Embryo, Mammalian; Glioma; Kinetics; Mice; Mice, Inbred Strains; Neuroblastoma; Neurons; PC12 Cells; Phospholipid Ethers; Platelet Activating Factor; Prenylamine; Pyridinium Compounds; Rats; Synaptosomes	1991
Presence of platelet-activating factor in pyuria in humans. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Chromatography, Thin Layer; Humans; Kinetics; Phospholipid Ethers; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Pyridinium Compounds; Pyuria; Rabbits	1991
The effect of CV-3988 and CV-6209 on the acute gastric erosions of rats due to water-immersion and restraint stress. Lipids, 1991, Volume: 26, Issue:12 Topics: Analysis of Variance; Animals; Gastric Mucosa; Immersion; Indomethacin; Male; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach; Stomach Ulcer; Stress, Physiological	1991
Involvement of platelet-activating factor in zymosan-induced rat pleurisy. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Cyproheptadine; Eosinophils; Inflammation; Leukocytes; Male; Mast Cells; Neutrophils; Platelet Activating Factor; Pleurisy; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Zymosan	1991
Platelet activating factor (PAF) antagonists: development of a highly potent PAF antagonist, TCV-309. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B Topics: Animals; Azepines; Humans; Isoquinolines; Molecular Structure; Niacinamide; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Rats; Structure-Activity Relationship; Tetrahydroisoquinolines; Triazoles	1991
Effects of the PAF-analog and -antagonist CV-6209 on cultured human glioma cell lines. Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 43, Issue:2 Topics: Cell Division; Cell Line; Cell Survival; DNA Replication; Glioma; Humans; Kinetics; Methionine; Neuroglia; Platelet Activating Factor; Pyridinium Compounds; Thymidine	1991
Platelet activating factor induces expression of early response genes c-fos and TIS-1 in human epidermoid carcinoma A-431 cells. Life sciences, 1991, Volume: 49, Issue:23 Topics: Cycloheximide; Gene Expression Regulation, Neoplastic; Genes, fos; Humans; Kinetics; Platelet Activating Factor; Pyridinium Compounds; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1991
Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; Femoral Artery; Heart Rate; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney; Male; Platelet Activating Factor; Prostaglandins; Pyridinium Compounds; Renal Circulation; Time Factors; Vasoconstriction	1991
Role of endogenous platelet-activating factor(PAF) in stress-induced hemorrhagic pancreatitis in rats. Gastroenterologia Japonica, 1991, Volume: 26, Issue:1 Topics: Animals; Ceruletide; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Stress, Physiological	1991
Effects of PAF on isolated rat airways perfused with blood-free solution. The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 1 Topics: Acetylcholine; Animals; Blood; Bronchi; Dose-Response Relationship, Drug; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Pyridinium Compounds; Rats; Rats, Inbred Strains; Regional Blood Flow; Tachyphylaxis	1991
Effect of a platelet activating factor antagonist and antithrombin III on septicemia and endotoxemia in rats. The Tohoku journal of experimental medicine, 1991, Volume: 163, Issue:3 Topics: Animals; Antithrombin III; Disseminated Intravascular Coagulation; Endotoxins; Kidney; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Sepsis; Toxemia	1991
Pregnancy suppression by a structurally related antagonist for platelet activating factor, CV-6209, in mice. Asia-Oceania journal of obstetrics and gynaecology, 1990, Volume: 16, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Embryo Implantation; Embryonic and Fetal Development; Embryonic Development; Female; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Count; Pregnancy; Pregnancy, Animal; Pyridinium Compounds; Thrombocytopenia; Time Factors	1990
[Antigen-induced biphasic eosinophil infiltration in the airways of actively sensitized guinea pigs and its inhibition by PAF antagonist and cyclosporin A]. Arerugi = [Allergy], 1990, Volume: 39, Issue:6 Topics: Animals; Asthma; Bronchi; Cyclosporins; Eosinophilia; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridinium Compounds; Time	1990
[An experimental study on shock after temporary hepatic inflow occlusion and platelet activating factor (PAF)]. Nihon Geka Gakkai zasshi, 1990, Volume: 91, Issue:10 Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Constriction; Liver; Male; Mitochondria; Platelet Activating Factor; Portasystemic Shunt, Surgical; Pyridinium Compounds; Rats; Rats, Inbred Strains; Shock	1990
[Bronchial hyperresponsiveness to histamine in guinea pig induced by intravenous administration of platelet activating factor]. Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:11 Topics: Airway Resistance; Animals; Bronchi; Guinea Pigs; Histamine; Infusions, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds	1990
The effect of platelet-activating factor on [14C]aminopyrine uptake by isolated guinea pig parietal cells. Biochemical and biophysical research communications, 1990, May-16, Volume: 168, Issue:3 Topics: Aminopyrine; Analysis of Variance; Animals; Calcium; Carbachol; Gastric Acid; Guinea Pigs; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Platelet Activating Factor; Pyridinium Compounds	1990
Gastric hemodynamic disturbance induced by hemorrhagic shock in rats. Role of platelet-activating factor. Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:6 Topics: Animals; Gastric Mucosa; Hemodynamics; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Reperfusion Injury; Shock, Hemorrhagic; Time Factors	1990
Agonist and antagonist of oxygen free radical. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2 Topics: Cells, Cultured; Endotoxins; Humans; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Pyridinium Compounds; Temperature; Tetradecanoylphorbol Acetate; Verapamil	1990
Effect of a platelet activating factor antagonist (CV6209) on shock caused by temporary hepatic inflow occlusion. Life sciences, 1990, Volume: 47, Issue:6 Topics: Analysis of Variance; Animals; Blood Pressure; Hypotension; Ligation; Liver; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Shock	1990
Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells. Biochemical and biophysical research communications, 1990, Jan-15, Volume: 166, Issue:1 Topics: Animals; Aorta, Thoracic; Blotting, Northern; Cells, Cultured; Endothelins; Endothelium, Vascular; Gene Expression; Humans; Indomethacin; Interleukin-1; Kinetics; Peptide Biosynthesis; Peptides; Platelet Activating Factor; Pyridinium Compounds; Recombinant Proteins; RNA, Messenger; Swine; Transcription, Genetic	1990
Protective effects of a platelet activating factor (PAF) antagonist and its combined treatment with prostaglandin (PG) E1 in traumatic shock. Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:5 Topics: Alprostadil; Animals; Blood Pressure; Cathepsin D; Drug Therapy, Combination; Male; Myocardial Depressant Factor; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Shock, Traumatic; Time Factors	1988
Desensitization of platelet-activating factor-stimulated protein phosphorylation in platelets. Molecular pharmacology, 1989, Volume: 35, Issue:4 Topics: Animals; Blood Platelets; In Vitro Techniques; Molecular Weight; Phospholipid Ethers; Phosphoproteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Quinolines; Quinolinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases	1989
Antagonism of platelet activating factor receptor binding and stimulated phosphoinositide-specific phospholipase C in rabbit platelets. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3 Topics: Animals; Blood Platelets; Enzyme Activation; In Vitro Techniques; Phosphatidylinositols; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Quinolines; Quinolinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Type C Phospholipases	1989
Platelet-activating factor causes goblet cell depletion in the conjunctiva. European journal of pharmacology, 1989, Sep-01, Volume: 168, Issue:1 Topics: Animals; Capillary Permeability; Conjunctiva; Guinea Pigs; Histamine; In Vitro Techniques; Leukocytes; Leukotriene E4; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; SRS-A	1989
CV 6209 is a non-competitive antagonist of platelet-activating factor receptors on guinea-pig resident peritoneal macrophages. Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:11 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Epoprostenol; Guinea Pigs; In Vitro Techniques; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1989
Endothelium-dependent vasodilator effects of platelet activating factor on rat resistance vessels. British journal of pharmacology, 1989, Volume: 98, Issue:4 Topics: Acetylcholine; Animals; Detergents; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vascular Resistance	1989
Endothelin-induced mobilization of Ca2+ and the possible involvement of platelet activating factor and thromboxane A2. Biochemical and biophysical research communications, 1989, Apr-28, Volume: 160, Issue:2 Topics: Animals; Benzofurans; Calcium; Cells, Cultured; Endothelins; Endothelium, Vascular; Fluorescent Dyes; Fura-2; Male; Muscle, Smooth, Vascular; Peptides; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Thromboxane A2	1989
Endothelin-induced sudden death and the possible involvement of platelet activating factor (PAF). Life sciences, 1989, Volume: 45, Issue:20 Topics: Animals; Aspirin; Azepines; Blood Pressure; Death, Sudden; Dexamethasone; Diltiazem; Electrocardiography; Endothelins; Guinea Pigs; Hypertension; Hypotension; Male; Mice; Mice, Inbred ICR; Peptides; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Triazines; Triazoles	1989
Platelet activating factor antagonists: synthesis and structure-activity studies of novel PAF analogues modified in the phosphorylcholine moiety. Journal of medicinal chemistry, 1989, Volume: 32, Issue:1 Topics: Animals; Blood Pressure; Chemical Phenomena; Chemistry; In Vitro Techniques; Mice; Platelet Activating Factor; Platelet Aggregation; Pyridinium Compounds; Rabbits; Rats; Structure-Activity Relationship	1989
Role of platelet activating factor in propagation of cardiac damage during myocardial ischemia. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:3 Topics: Animals; Blood Pressure; Capillary Permeability; Coronary Disease; Heart; Heart Rate; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains	1988
Salutary consequences of blockade of platelet activating factor in hemorrhagic shock. European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3 Topics: Animals; Blood Pressure; Cathepsin D; Male; Myocardial Depressant Factor; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Shock, Hemorrhagic	1988
[Effect of a platelet activating factor (PAF) antagonist on the hepatic afferent vascular occlusion]. Nihon Geka Gakkai zasshi, 1988, Volume: 89, Issue:5 Topics: Animals; Hepatic Veno-Occlusive Disease; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains	1988
CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1 Topics: Animals; Blood Platelets; Blood Pressure; Humans; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Serotonin	1987
Spatial heterogeneity of mucosal blood flow during ischemia-reperfusion injury of rat stomach investigated by laser Doppler perfusion imaging. Journal of gastroenterology, 1995, Volume: 30, Issue:3 Topics: Analysis of Variance; Animals; Blood Flow Velocity; Gastric Mucosa; Hemodynamics; Ischemia; Laser-Doppler Flowmetry; Male; Microcirculation; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Reperfusion Injury; Stomach	1995
Leukotriene B4 mediates substance P-induced granulocyte infiltration into mouse skin. Comparison with antigen-induced granulocyte infiltration. Journal of immunology (Baltimore, Md. : 1950), 1993, Aug-15, Volume: 151, Issue:4 Topics: Animals; Cell Degranulation; Chemotaxis, Leukocyte; Eosinophils; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin Physiological Phenomena; Substance P	1993
Role of leukotriene B4 in substance P-induced granulocyte infiltration in mouse skin. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Granulocytes; Leukotriene B4; Mast Cells; Mice; Mice, Inbred BALB C; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Skin; Skin Physiological Phenomena; Substance P	1993
Characterization of a behavioral model for peripherally evoked itch suggests platelet-activating factor as a potent pruritogen. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2 Topics: Animals; Azepines; Female; Guinea Pigs; Histamine; Male; Platelet Activating Factor; Pruritus; Pyridinium Compounds; Triazoles	1995
Mechanism of the contractile response to platelet-activating factor (PAF) of the rat stomach fundus. I. PAF-induced contractile response and calcium mobilization. General pharmacology, 1993, Volume: 24, Issue:6 Topics: Animals; Calcium; Gastric Fundus; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar	1993
Effect of platelet-activating factor on intracellular free calcium in cow tracheal epithelium. American journal of respiratory cell and molecular biology, 1994, Volume: 10, Issue:3 Topics: Animals; Bradykinin; Calcium; Cattle; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fura-2; Inositol 1,4,5-Trisphosphate; Platelet Activating Factor; Pyridinium Compounds; Trachea; Verapamil	1994
Evidence for production of platelet-activating factor by yeast Saccharomyces cerevisiae cells. Biochimica et biophysica acta, 1994, Mar-02, Volume: 1199, Issue:2 Topics: Chromatography, Thin Layer; Furans; Gas Chromatography-Mass Spectrometry; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Protein Precursors; Pyridinium Compounds; Saccharomyces cerevisiae	1994
Effects of a platelet-activating factor antagonist at different doses given simultaneously with double-filtration plasmapheresis on cardiac xenograft survival. Transplantation proceedings, 1994, Volume: 26, Issue:2 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Graft Survival; Heart Rate; Heart Transplantation; Plasmapheresis; Platelet Activating Factor; Pyridinium Compounds; Swine; Transplantation, Heterologous	1994
Verotoxin induces hemorrhagic lesions in rat small intestine. Temporal alteration of vasoactive substances. Digestive diseases and sciences, 1994, Volume: 39, Issue:6 Topics: Animals; Bacterial Toxins; Enterotoxins; Escherichia coli; Free Radicals; Gastrointestinal Hemorrhage; Injections, Intra-Arterial; Intestine, Small; Laser-Doppler Flowmetry; Male; Microcirculation; Neutrophils; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Shiga Toxin 1; Tissue Plasminogen Activator	1994
Platelet activating factor interaction with tumor necrosis factor in myocardial ischaemia-reperfusion injury. Journal of lipid mediators, 1993, Volume: 8, Issue:1 Topics: Analysis of Variance; Animals; Biological Assay; Creatine Kinase; Isoenzymes; Leukopenia; Macrophages; Male; Myocardial Ischemia; Myocardial Reperfusion; Necrosis; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha	1993
Platelet-activating-factor-induced changes in cardiovascular function and oxyradical status of myocardium in presence of the PAF antagonist CV-6209. Angiology, 1994, Volume: 45, Issue:1 Topics: Animals; Creatine Kinase; Dogs; Female; Free Radicals; Heart; Hemodynamics; Hydrogen-Ion Concentration; Lactates; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Contraction; Myocardium; Oxygen; Platelet Activating Factor; Pyridinium Compounds; Ventricular Function, Left	1994
Early release of neutrophil chemotactic factor from isolated rat heart subjected to regional ischaemia followed by reperfusion. Cardiovascular research, 1993, Volume: 27, Issue:12 Topics: Animals; Chemotaxis; Disease Models, Animal; Hot Temperature; Interleukin-8; Isoquinolines; Male; Myocardial Reperfusion Injury; Myocardium; Phenylpropionates; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Tetrahydroisoquinolines; Time Factors	1993
Role of endothelin and platelet-activating factor in indomethacin-induced gastric mucosal injury in rats. Digestion, 1993, Volume: 54, Issue:3 Topics: Animals; Endothelins; Gastric Mucosa; Gastritis; Immunization, Passive; Indomethacin; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley	1993
Protective effect of platelet-activating factor antagonist on ischemia-induced liver injury in rats. Surgery, 1993, Volume: 113, Issue:1 Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Bile; Bile Ducts, Intrahepatic; Dose-Response Relationship, Drug; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar	1993
Platelet-activating factor (PAF) in male reproductive organs of guinea pigs and rats: effect of androgen on PAF in seminal vesicles. Biology of reproduction, 1993, Volume: 48, Issue:2 Topics: Animals; Castration; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Furans; Gene Expression Regulation; Genitalia, Male; Guinea Pigs; Male; Microscopy, Electron; Organ Size; Platelet Activating Factor; Platelet Aggregation; Pyridinium Compounds; Rats; Rats, Wistar; Seminal Vesicles; Testosterone	1993
Platelet-activating factor and cerebral vasospasm following subarachnoid hemorrhage. Journal of neurosurgery, 1993, Volume: 78, Issue:4 Topics: Animals; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Immunoglobulin G; Ischemic Attack, Transient; Lactones; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Subarachnoid Hemorrhage	1993
Platelet activating factor mediates systemic circulatory collapse after temporary hepatic inflow occlusion. Transplantation proceedings, 1993, Volume: 25, Issue:2 Topics: Animals; Blood Pressure; Heparin; Hypotension; Liver Circulation; Male; Platelet Activating Factor; Portal System; Pyridinium Compounds; Rats; Rats, Wistar; Splanchnic Circulation	1993
Attenuation of endotoxin-induced intestinal microcirculatory damage by eicosapentanoic acid. The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 1 Topics: Animals; Blood Flow Velocity; Cell Adhesion; Edema; Eicosapentaenoic Acid; Endotoxins; Erythrocytes; Escherichia coli; Fatty Acids; Ileum; Intestinal Mucosa; Leukocytes; Male; Microcirculation; Phospholipids; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Venules	1993
Effects of platelet activating factor on mouse embryo implantation in vitro. Journal of assisted reproduction and genetics, 1995, Volume: 12, Issue:5 Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Embryo Implantation; Embryo Transfer; Embryo, Mammalian; Endometrium; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Platelet Activating Factor; Pyridinium Compounds	1995
Oxidative stress in gastric mucosal injury: role of platelet-activating factor-activated granulocytes. Journal of gastroenterology, 1995, Volume: 30, Issue:5 Topics: Animals; Electric Stimulation; Fluoresceins; Free Radical Scavengers; Gastric Mucosa; Granulocytes; Luminescent Measurements; Male; Microcirculation; Microscopy, Fluorescence; Oxidative Stress; Peroxidase; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Superoxide Dismutase	1995
Role of endogenous platelet-activating factor in the regulation of pancreatic blood flow during caerulein stimulation. Journal of gastroenterology, 1996, Volume: 31, Issue:3 Topics: Animals; Ceruletide; Cholecystokinin; Gastrointestinal Agents; Hormone Antagonists; Laser-Doppler Flowmetry; Male; Pancreas; Platelet Activating Factor; Proglumide; Pyridinium Compounds; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Time Factors	1996
Mechanisms of desensitization of vasodilatation induced by platelet-activating factor in hypertensive rats. European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3 Topics: Acetylcholine; Animals; Cyclic GMP; GTP-Binding Proteins; Hypertension; Hypertension, Renovascular; In Vitro Techniques; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Vasodilation; Virulence Factors, Bordetella	1996
Arrhythmias caused by platelet activating factor. Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Female; Lidocaine; Male; Membrane Potentials; Patch-Clamp Techniques; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrodotoxin	1996
Thromboxane rather than platelet activating factor mediates pulmonary vasoconstriction after antigen challenge in rabbits. Shock (Augusta, Ga.), 1996, Volume: 6, Issue:3 Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Enzyme Inhibitors; Humans; Immunization; Indomethacin; Lung; Methacrylates; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Pyridinium Compounds; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction	1996
CV6209 inhibits airway wall thickening and airway hyperresponsiveness to histamine induced by intravenous administration of platelet-activating factor in guinea pigs. Journal of lipid mediators and cell signalling, 1996, Volume: 13, Issue:2 Topics: Airway Resistance; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine Antagonists; Lung; Male; Platelet Activating Factor; Pyridinium Compounds	1996
Prednisolone, platelet-activating factor receptor antagonist, or superoxide dismutase reduced leukocyte entrapment induced by interferon alpha in retinal microcirculation. Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:5 Topics: Acridine Orange; Animals; Antiviral Agents; Capillaries; Cell Adhesion; Cell Movement; Endothelium, Vascular; Fluorescein Angiography; Fluorescent Dyes; Fluorophotometry; Glucocorticoids; Leukocytes; Microcirculation; Platelet Activating Factor; Prednisolone; Pyridinium Compounds; Rats; Retinal Vessels; Superoxide Dismutase	1997
Involvement of platelet-activating factor (PAF) in glutamate neurotoxicity in rat neuronal cultures. Brain research, 1997, Apr-18, Volume: 754, Issue:1-2 Topics: Animals; Cells, Cultured; Cerebral Cortex; Diterpenes; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibrinolytic Agents; Fluorescent Dyes; Fura-2; Ginkgolides; Glutamic Acid; Immunoglobulin G; Lactones; Neurons; Neurotoxins; Platelet Activating Factor; Pyridinium Compounds; Rats	1997
Electrophysiologic effects of interactions between activated canine neutrophils and cardiac myocytes. Journal of cardiovascular electrophysiology, 1997, Volume: 8, Issue:6 Topics: Action Potentials; Animals; Dogs; Female; Heart; In Vitro Techniques; Male; Myocardium; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled	1997
Eicosanoid production from porcine neutrophils and platelets: differential production with various agonists. The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1 Topics: Animals; Blood Platelets; Calcimycin; Cell Communication; Complement C5a; Cytochalasin B; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxins; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Recombinant Proteins; Swine; Thromboxane A2	1997
Role of platelet-activating factor in two-kidney, one-clip hypertension. International journal of urology : official journal of the Japanese Urological Association, 1997, Volume: 4, Issue:4 Topics: Animals; Blood Pressure; Diacylglycerol Cholinephosphotransferase; Hypertension, Renovascular; Injections, Intravenous; Kidney Medulla; Male; Organ Size; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Renal Circulation	1997
A platelet activating factor antagonist attenuates the effects of testicular ischemia. The Journal of urology, 1997, Volume: 158, Issue:3 Pt 2 Topics: Animals; Ischemia; Male; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Spermatic Cord Torsion; Testis	1997
Involvement of platelet-activating factor in cell death induced under ischemia/postischemia-like conditions in an immortalized hippocampal cell line. Journal of neurochemistry, 1998, Volume: 70, Issue:3 Topics: Azepines; Calcium; Cell Death; Cell Line, Transformed; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Ischemia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Signal Transduction; Triazoles	1998
A new platelet-activating factor antagonist (CV-6209) in preservation of heart and lung for transplantation. Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:6 Topics: Animals; Female; Heart; Heart Transplantation; Lung; Lung Transplantation; Organ Preservation; Platelet Activating Factor; Pyridinium Compounds; Respiratory Mechanics; Swine; Vascular Resistance	1997
Inhibition of tumor necrosis factor-alpha production by SK&F 98625, a CoA-independent transacylase inhibitor, in cultured rat peritoneal macrophages. Life sciences, 1998, Volume: 62, Issue:20 Topics: Acyltransferases; Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha	1998
Role of platelet-activating factor in long-term potentiation of the rat medial vestibular nuclei. Journal of neurophysiology, 1998, Volume: 79, Issue:6 Topics: Animals; Diterpenes; Ginkgolides; In Vitro Techniques; Lactones; Long-Term Potentiation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Synaptic Transmission; Vestibular Nuclei	1998
Platelet-activating factor is a key mediator of pulmonary vasoconstriction and bronchoconstriction after antigen challenge in the perfused sensitized rabbit lung. Shock (Augusta, Ga.), 1998, Volume: 9, Issue:6 Topics: Animals; Antigens; Bronchoconstriction; Culture Techniques; Erythrocytes; Humans; Lung; Perfusion; Platelet Activating Factor; Pulmonary Circulation; Pyridinium Compounds; Rabbits; Vasoconstriction	1998
Platelet-activating factor mediates intercellular adhesion molecule-1-dependent radical production in the nonhypoxic ischemia rat lung. American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:1 Topics: Animals; Antibodies, Monoclonal; Capillaries; Capillary Permeability; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Ischemia; Leukocytes; Lung; Male; Oxygen; Platelet Activating Factor; Pulmonary Artery; Pyridinium Compounds; Rats; Rats, Wistar	1998
Suppressive effects of antihistaminic and/or anti-PAF agents on passive anaphylactic shock in mice sensitized with allogeneic monoclonal IgE and IgG1 antibodies and hyperimmune serum. Immunological investigations, 1998, Volume: 27, Issue:6 Topics: Anaphylaxis; Animals; Antibodies, Monoclonal; Cattle; Cyproheptadine; Female; Histamine H1 Antagonists; Immunoglobulin E; Immunoglobulin G; Immunosuppressive Agents; Isoantibodies; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Nude; Piperazines; Platelet Activating Factor; Propranolol; Pyridinium Compounds; Serum Albumin, Bovine; Triprolidine	1998
Strategies of myocardial protection for operation in chronic model of cyanotic heart disease. The Annals of thoracic surgery, 1998, Volume: 66, Issue:5 Topics: Animals; Cardiopulmonary Bypass; Chronic Disease; Disease Models, Animal; Filtration; Heart; Heart Arrest, Induced; Heart Defects, Congenital; Injections, Intravenous; Lymphocyte Depletion; Myocardial Contraction; Platelet Activating Factor; Pyridinium Compounds; Swine	1998
Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG. Journal of immunology (Baltimore, Md. : 1950), 1999, Mar-01, Volume: 162, Issue:5 Topics: Eicosanoids; Eosinophils; Humans; Immunoglobulin G; Interleukin-5; Pertussis Toxin; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyridinium Compounds; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella	1999
Platelet-activating factor increases the expression of metalloproteinase-9 in human bronchial epithelial cells. European journal of pharmacology, 1999, Jun-11, Volume: 374, Issue:1 Topics: Bronchi; Cells, Cultured; Collagenases; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Matrix Metalloproteinase 9; Molecular Weight; Platelet Activating Factor; Pyridinium Compounds; RNA, Messenger	1999
Possible participation of intracellular platelet-activating factor in tumor necrosis factor-alpha production by rat peritoneal macrophages. European journal of pharmacology, 1999, Jun-25, Volume: 374, Issue:3 Topics: Animals; Azepines; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Furans; Imidazoles; Indomethacin; Macrophages, Peritoneal; Male; Organophosphorus Compounds; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thapsigargin; Triazoles; Tumor Necrosis Factor-alpha	1999
Motility induced by human immunodeficiency virus-1 Tat on Kaposi's sarcoma cells requires platelet-activating factor synthesis. The American journal of pathology, 1999, Volume: 155, Issue:5 Topics: Azepines; Cell Movement; Diterpenes; Dose-Response Relationship, Drug; Fibrinolytic Agents; Gene Products, tat; Ginkgolides; HIV-1; Humans; Lactones; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sarcoma, Kaposi; tat Gene Products, Human Immunodeficiency Virus; Triazoles; Tumor Cells, Cultured	1999
Endothelial cells potentiate phagocytic killing by macrophages via platelet-activating factor release. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:1 Topics: Animals; Azepines; Cell Death; Cell Line; Coculture Techniques; Dose-Response Relationship, Drug; Endothelium, Vascular; Macrophages, Peritoneal; Mice; Phagocytes; Phagocytosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Triazoles; Tumor Necrosis Factor-alpha	2000
Lipid mediators stimulate reactive oxygen species formation in immortalized human keratinocytes. Advances in experimental medicine and biology, 1999, Volume: 469 Topics: Calcium; Cell Line; Ceramides; Diterpenes; Ginkgolides; Humans; Keratinocytes; Lactones; Lipid Metabolism; Lipids; Luminescent Measurements; Lysophosphatidylcholines; Membrane Lipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction	1999
Possible involvement of endothelium-derived hyperpolarizing factor (EDHF) in the depressor responses to platelet activating factor (PAF) in rats. British journal of pharmacology, 2000, Volume: 131, Issue:6 Topics: Animals; Apamin; Biological Factors; Blood Pressure; Charybdotoxin; Depression, Chemical; Endothelin-1; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar	2000
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors. Journal of immunology (Baltimore, Md. : 1950), 2001, May-15, Volume: 166, Issue:10 Topics: Arachidonate 5-Lipoxygenase; Cells, Cultured; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; Down-Regulation; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukocyte Count; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Solubility; Tumor Necrosis Factor-alpha; Up-Regulation	2001
Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor. Experimental lung research, 2001, Volume: 27, Issue:4 Topics: Animals; Animals, Newborn; Arachidonic Acid; Benzoquinones; In Vitro Techniques; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Platelet Activating Factor; Pulmonary Artery; Pulmonary Veins; Pyridinium Compounds; Sheep	2001
Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:2 Topics: Azepines; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fatty Acids, Omega-3; Humans; Intercellular Adhesion Molecule-1; Monocytes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thienopyridines; Triazoles; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2002
Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures. Brain research, 2002, Aug-09, Volume: 946, Issue:1 Topics: Animals; Arachidonic Acid; Astrocytes; Binding Sites; Cells, Cultured; Cerebral Cortex; Dinoprostone; Diterpenes; Drug Synergism; Female; Ginkgolides; Lactones; Osmolar Concentration; Phospholipid Ethers; Platelet Activating Factor; Pyridinium Compounds; Rats; Solvents	2002
Molecular mechanisms for lipopolysaccharide-induced biphasic activation of nuclear factor-kappa B (NF-kappa B). The Journal of biological chemistry, 2002, Nov-22, Volume: 277, Issue:47 Topics: Animals; Azepines; Cell Line; Female; Interleukin-1; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Platelet Activating Factor; Pyridinium Compounds; Receptors, Interleukin-1; Signal Transduction; Time Factors; Triazoles; Tumor Necrosis Factor-alpha	2002
Structural determinants of blockade of eosinophil activation, adhesion and secretion by synthetic analogs of phomactin. Life sciences, 2003, Oct-24, Volume: 73, Issue:23 Topics: Cell Adhesion; Dose-Response Relationship, Drug; Eosinophils; Epoxy Compounds; Heterocyclic Compounds; Humans; Leukotriene C4; Platelet Activating Factor; Pyridinium Compounds; Structure-Activity Relationship; Superoxides	2003
Platelet-activating factor acts on cortisol secretion by perfused guinea-pig adrenals via calcium-/phospholipid-dependent mechanisms. The Journal of endocrinology, 2005, Volume: 184, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcium; Colforsin; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Drug Synergism; Enzyme Activation; Guinea Pigs; Hydrocortisone; Ionophores; Isoquinolines; Male; Perfusion; Phospholipid Ethers; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyridinium Compounds; Receptors, G-Protein-Coupled; Secretory Rate	2005
Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid. Biochimica et biophysica acta, 2006, Volume: 1761, Issue:7 Topics: Cell Adhesion; Cell Communication; Cells, Cultured; Diterpenes; Endothelium, Vascular; Ginkgolides; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Lactones; Linoleic Acids, Conjugated; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2006
Anaphylactic reaction induced by Toxoplasma gondii-derived heat shock protein 70. International immunology, 2006, Volume: 18, Issue:10 Topics: Anaphylaxis; Animals; HSP70 Heat-Shock Proteins; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Knockout; Platelet Activating Factor; Protozoan Proteins; Pyridinium Compounds; Toxoplasma; Toxoplasmosis, Animal	2006
Changes in self-reactive IgG antibody repertoire after treatment of experimental autoimmune encephalomyelitis with anti-allergic drugs. Journal of neuroimmunology, 2007, Volume: 182, Issue:1-2 Topics: Animals; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Central Nervous System; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Female; Histamine Antagonists; Histamine H1 Antagonists; Immunoblotting; Immunoglobulin G; Intermediate Filament Proteins; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteomics; Pyridinium Compounds; Pyrilamine; Receptors, G-Protein-Coupled; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2007
Vimentin autoantibodies induce platelet activation and formation of platelet-leukocyte conjugates via platelet-activating factor. Journal of leukocyte biology, 2008, Volume: 83, Issue:2 Topics: Apoptosis; Autoantibodies; Autoimmune Diseases; Blood Platelets; Cell Adhesion; Complement C3d; Culture Media, Conditioned; Fibrinogen; Humans; Immunoglobulin M; Immunosorbent Techniques; Leukocytes; P-Selectin; Platelet Activating Factor; Platelet Activation; Pyridinium Compounds; Recombinant Proteins; Thrombophilia; Thromboplastin; Vimentin	2008
PAF, rather than histamine, participates in mouse anaphylactic hypotension. Pharmacology, 2008, Volume: 82, Issue:2 Topics: Anaphylaxis; Animals; Blood Pressure; Diphenhydramine; Histamine; Histamine H1 Antagonists; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Receptors, Histamine H1	2008
Anaphylaxis to a self-peptide in the absence of mast cells or histamine. Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:4 Topics: Adjuvants, Immunologic; Anaphylaxis; Animals; Bacterial Toxins; Bordetella pertussis; Encephalomyelitis, Autoimmune, Experimental; Glycoproteins; Histamine; Histidine Decarboxylase; Immunization; Immunoglobulin E; Interleukin-4; Mast Cells; Mice; Mice, Knockout; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Platelet Activating Factor; Pyridinium Compounds; Th1 Cells; Th2 Cells	2009
Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine. Life sciences, 2014, Oct-29, Volume: 116, Issue:2 Topics: Anaphylaxis; Animals; Arterial Pressure; Cardiac Output; Diphenhydramine; Hemodynamics; Histamine; Hypotension; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, G-Protein-Coupled; Vascular Resistance; Vasoconstriction; Vasodilation	2014