Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cimetidine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with cimetidine in 13 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(cimetidine)
Trials
(cimetidine)
Recent Studies (post-2010) (cimetidine)
9,1561875529,4731,687377

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)cimetidine (IC50)
Solute carrier family 22 member 1Mus musculus (house mouse)0.59
Solute carrier family 22 member 2Mus musculus (house mouse)8
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)0.82
Histamine H2 receptorHomo sapiens (human)1.1742
Histamine H2 receptorCavia porcellus (domestic guinea pig)1.02
Potassium-transporting ATPase subunit betaHomo sapiens (human)0.82
Multidrug and toxin extrusion protein 1Homo sapiens (human)3.0333

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's12 (92.31)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corfield, DR; Webber, SE; Widdicombe, JG1
Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB1
Cordeiro, RS; Watson, ML; Weg, VB; Williams, TJ1
Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M1
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D1
Northover, AM1
Ackerman, Z; Karmeli, F; Ligumsky, M; Rachmilewitz, D1
Alloatti, G; Camussi, G; Emanuelli, G; Mariano, F; Meda, E; Montrucchio, G; Tetta, C1
Lu, Z; Wolf, MB1
Halonen, M; Lohman, IC1
Archer, CB; Brooks, J; Burton, JL; Sansom, JE1
Czarnetzki, BM; Hartmann, K; Pfrommer, C; Schwarz, S; Zuberbier, T1
Akiyama, K; Maeda, Y; Mita, H; Saito, H; Shimizu, H1

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cimetidine

ArticleYear
Effects of H1- and H2-antihistamines on platelet-activating factor and bradykinin-induced inflammatory responses in human skin.
    Clinical and experimental dermatology, 1996, Volume: 21, Issue:1

    Topics: Administration, Oral; Bradykinin; Cimetidine; Codeine; Double-Blind Method; Doxepin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Platelet Activating Factor; Skin; Terfenadine; Urticaria

1996

Other Studies

12 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and cimetidine

ArticleYear
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance

1991
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles

1991
Histamine, leukotriene D4 and platelet-activating factor in guinea pig passive cutaneous anaphylaxis.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: Acetophenones; Animals; Autacoids; Azepines; Blood Proteins; Bradykinin; Capillary Permeability; Chlorpheniramine; Cimetidine; Guinea Pigs; Histamine; Male; Methysergide; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; SRS-A; Tetrazoles; Triazoles

1991
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles

1990
Gastric mucosal damage by ethanol is mediated by substance P and prevented by ketotifen, a mast cell stabilizer.
    Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1

    Topics: Animals; Azepines; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Hydroxyzine; In Vitro Techniques; Ketotifen; Leukotriene B4; Male; Mast Cells; Pepsin A; Peptide Fragments; Platelet Activating Factor; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; SRS-A; Substance P; Triazoles

1991
Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Aminoquinolines; Animals; Bradykinin; Calcimycin; Calcium; Cimetidine; Endothelium, Vascular; Guinea Pigs; Histamine; Histamine Antagonists; Isoproterenol; Platelet Activating Factor; Pyrilamine; Vena Cava, Inferior

1990
Enhanced gastric and duodenal platelet-activating factor and leukotriene generation in duodenal ulcer patients.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:9

    Topics: Adult; Cimetidine; Duodenal Ulcer; Duodenum; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Leukotriene B4; Male; Middle Aged; Platelet Activating Factor; SRS-A

1990
The pattern of cardiovascular alterations induced by infusion of platelet-activating factor in rabbit is modified by pretreatment with H1-H2 receptor antagonists but not by cyclooxygenase inhibition.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Cyclooxygenase Inhibitors; Drug Interactions; Electrocardiography; Female; Hemodynamics; Histamine; Histamine Antagonists; Indomethacin; Infusions, Intravenous; Male; Platelet Activating Factor; Promethazine; Rabbits

1987
Platelet activating factor-induced microvascular permeability increases in the cat hindlimb.
    Circulatory shock, 1993, Volume: 41, Issue:1

    Topics: Animals; Azepines; Capillary Permeability; Cats; Cimetidine; Diphenhydramine; Endothelium, Vascular; Hindlimb; Histamine; Isoproterenol; Leukocyte Count; Leukocytes; Platelet Activating Factor; Triazoles

1993
The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit.
    The American review of respiratory disease, 1993, Volume: 147, Issue:5

    Topics: Airway Resistance; Anaphylaxis; Animals; Azepines; Basophil Degranulation Test; Blood Pressure; Chlorpheniramine; Cimetidine; Histamine; Immunoglobulin E; Leukocyte Count; Lung Compliance; Platelet Activating Factor; Rabbits; Serotonin; Tidal Volume; Triazoles

1993
Histamine releasability of basophils and skin mast cells in chronic urticaria.
    Allergy, 1996, Volume: 51, Issue:1

    Topics: Adult; Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Cimetidine; Female; Histamine Release; Humans; Immunoglobulin E; Interleukin-3; Leukotriene C4; Male; Mast Cells; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Skin; Urticaria

1996
Histamine augments VCAM-1 expression on IL-4- and TNF-alpha-stimulated human umbilical vein endothelial cells.
    International archives of allergy and immunology, 1996, Volume: 111, Issue:2

    Topics: Amanitins; Antibodies, Blocking; Antigens, CD; Cell Adhesion; Cells, Cultured; Cimetidine; Eosinophils; Histamine; Histamine Antagonists; Humans; Immunohistochemistry; Integrin alpha4; Interleukin-4; Piperidines; Platelet Activating Factor; Pyrilamine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1

1996