Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and choline

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with choline in 20 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(choline)
Trials
(choline)
Recent Studies (post-2010) (choline)
9,15618755219,6286084,345

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)choline (IC50)
Sodium- and chloride-dependent creatine transporter 1Rattus norvegicus (Norway rat)1.6
High affinity choline transporter 1Mus musculus (house mouse)1.6

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's11 (55.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dubyak, GR; el-Moatassim, C1
Ahmed, A; Ferriani, RA; Plevin, R; Smith, SK1
Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Till, U1
Bidault, J; Breton, M; Colard, O; Ninio, E1
Elrod, C; Hough, S; Parks, JE1
Mookerjea, S; Nagpurkar, A; Randell, E1
Burghardt, C; Janero, DR1
Maguire, MH; Marx, MH; Satchell, DG; Wiley, RA1
Nieto, ML; Sanchez Crespo, M; Velasco, S1
Daniel, LW; Waite, M; Wykle, RL1
Rink, TJ; Sage, SO1
Hanahan, DJ; Weintraub, ST1
Infante, JP1
Kawaguchi, H; Yasuda, H1
Kunievsky, B; Yavin, E1
Kester, M1
Kulikov, VI; Muzia, GI1
Misra, UK; Pizzo, SV1
Ibe, BO; Portugal, AM; Usha Raj, J1
Creer, MH; Crown, KN; Kell, PJ; McHowat, J; Wirsig, K1

Reviews

3 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and choline

ArticleYear
Platelet-activating factor isolation, identification, and assay.
    Methods of biochemical analysis, 1985, Volume: 31

    Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Choline; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Humans; Mass Spectrometry; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation

1985
Biosynthesis of acyl-specific glycerophospholipids in mammalian tissues. Postulation of new pathways.
    FEBS letters, 1984, May-07, Volume: 170, Issue:1

    Topics: Animals; Choline; Cytosine Nucleotides; Fatty Acids, Unsaturated; Lipoproteins; Models, Biological; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylinositols; Phospholipids; Platelet Activating Factor; Tissue Distribution

1984
[Biological role of cellular metabolites--structural analogs of platelet activating factor].
    Biokhimiia (Moscow, Russia), 1996, Volume: 61, Issue:3

    Topics: Animals; Cell Membrane; Choline; Humans; Platelet Activating Factor; Receptors, Cell Surface

1996

Other Studies

17 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and choline

ArticleYear
A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages.
    The Journal of biological chemistry, 1992, Nov-25, Volume: 267, Issue:33

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line, Transformed; Choline; Cytosol; Digitonin; Diglycerides; Enzyme Activation; Inositol Phosphates; Ionomycin; Kinetics; Macrophages; Mice; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phospholipase D; Phosphoric Diester Hydrolases; Platelet Activating Factor; Receptors, Purinergic; Simian virus 40; Tetradecanoylphorbol Acetate

1992
Platelet-activating factor mediates phosphatidylcholine hydrolysis by phospholipase D in human endometrium.
    Biology of reproduction, 1992, Volume: 47, Issue:1

    Topics: Choline; Chromatography, Ion Exchange; Dose-Response Relationship, Drug; Endometrium; Female; Humans; Hydrolysis; Phosphatidylcholines; Phospholipase D; Platelet Activating Factor; Tritium

1992
Stimulation of platelet-activating factor synthesis in human endothelial cells by activation of the de novo pathway. Phorbol 12-myristate 13-acetate activates 1-alkyl-2-lyso-sn-glycero-3-phosphate:acetyl-CoA acetyltransferase and dithiothreitol-insensitiv
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Acetates; Acetyltransferases; Arachidonic Acids; Cells, Cultured; Choline; Diacylglycerol Cholinephosphotransferase; Dithiothreitol; Endothelium, Vascular; Humans; Kinetics; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins

1991
Biosynthesis of paf-acether. XVII. Regulation by the CoA-independent transacylase in human neutrophils.
    FEBS letters, 1991, Sep-09, Volume: 289, Issue:2

    Topics: Acetates; Acetyltransferases; Acyltransferases; Choline; Homeostasis; Humans; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1991
Platelet activating factor activity in the phospholipids of bovine spermatozoa.
    Biology of reproduction, 1990, Volume: 43, Issue:5

    Topics: Animals; Cardiolipins; Cattle; Choline; Chromatography, Thin Layer; Ethers; Male; Phosphatidylethanolamines; Phospholipids; Platelet Activating Factor; Serotonin; Spermatozoa; Tritium

1990
Interaction between rat serum phosphorylcholine binding protein and platelet activating factor.
    Biochemical and biophysical research communications, 1990, Mar-16, Volume: 167, Issue:2

    Topics: Animals; Carrier Proteins; Choline; Chromatography, Gel; Chromatography, High Pressure Liquid; Phosphorylcholine; Platelet Activating Factor; Protein Binding; Rats; Rats, Inbred Strains

1990
Production and release of platelet-activating factor by the injured heart-muscle cell (cardiomyocyte).
    Research communications in chemical pathology and pharmacology, 1990, Volume: 67, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Activation; Heart Injuries; Lipid Metabolism; Myocardium; Phospholipases A; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Darmstoff analogues. 3. Actions of choline esters of acetal phosphatidic acids on visceral smooth muscle.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Chemical Phenomena; Chemistry; Choline; Colon; Dose-Response Relationship, Drug; Esterification; Esters; Guinea Pigs; Molecular Structure; Muscle Contraction; Muscle, Smooth; Phosphatidic Acids; Platelet Activating Factor; Structure-Activity Relationship; Trachea

1989
Biosynthesis of platelet-activating factor in human polymorphonuclear leukocytes. Involvement of the cholinephosphotransferase pathway in response to the phorbol esters.
    The Journal of biological chemistry, 1988, Feb-15, Volume: 263, Issue:5

    Topics: Acetyltransferases; Calcimycin; Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Dithiothreitol; Dose-Response Relationship, Drug; Glyceryl Ethers; Humans; Neutrophils; Phorbol Esters; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1988
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
    The Journal of biological chemistry, 1986, Jul-15, Volume: 261, Issue:20

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Choline; Diglycerides; Dogs; Glycerides; Kidney; Palmitic Acid; Palmitic Acids; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Tetradecanoylphorbol Acetate

1986
Effects of ionic substitution on [Ca2+]i rises evoked by thrombin and PAF in human platelets.
    European journal of pharmacology, 1986, Aug-22, Volume: 128, Issue:1-2

    Topics: Blood Platelets; Calcium; Choline; Humans; In Vitro Techniques; Kinetics; Platelet Activating Factor; Platelet Aggregation; Sodium; Thrombin

1986
Platelet-activating factor stimulates phospholipase in quiescent Swiss mouse 3T3 fibroblast.
    FEBS letters, 1984, Oct-15, Volume: 176, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Choline; Diglycerides; Enzyme Activation; Fibroblasts; Kinetics; Mice; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Type C Phospholipases

1984
Production and metabolism of platelet-activating factor in the normal and ischemic fetal rat brain.
    Journal of neurochemistry, 1994, Volume: 63, Issue:6

    Topics: Animals; Biological Assay; Blood Platelets; Brain; Calcimycin; Choline; Half-Life; Ischemic Attack, Transient; Kinetics; Phosphatidylinositol Phosphates; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Tritium; Type C Phospholipases

1994
Platelet-activating factor stimulates phosphatidic acid formation in cultured rat mesangial cells: roles of phospholipase D, diglyceride kinase, and de novo phospholipid synthesis.
    Journal of cellular physiology, 1993, Volume: 156, Issue:2

    Topics: Animals; Cells, Cultured; Choline; Diacylglycerol Kinase; Ethanolamines; Glomerular Mesangium; Glycerol; Hydrolysis; Male; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Phosphorus Radioisotopes; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors; Tritium

1993
Ligation of the alpha 2-macroglobulin signaling receptor on macrophages induces synthesis of platelet activating factor.
    Journal of cellular biochemistry, 1996, Volume: 61, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Alkaloids; alpha-Macroglobulins; Animals; Cells, Cultured; Choline; Cycloheximide; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Mice; Mice, Inbred C57BL; Pertussis Toxin; Phospholipases A; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Specific Pathogen-Free Organisms; Staurosporine; Virulence Factors, Bordetella

1996
Metabolism of platelet activating factor by intrapulmonary vascular smooth muscle cells. Effect of oxygen on phospholipase A2 protein expression and activities of acetyl-CoA acetyltransferase and cholinephosphotransferase.
    Molecular genetics and metabolism, 2002, Volume: 77, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyl-CoA C-Acetyltransferase; Animals; Choline; Diacylglycerol Cholinephosphotransferase; Female; Lung; Muscle, Smooth, Vascular; Oxygen; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sheep

2002
Inhibition of platelet-activating factor (PAF) acetylhydrolase by methyl arachidonyl fluorophosphonate potentiates PAF synthesis in thrombin-stimulated human coronary artery endothelial cells.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arachidonic Acids; Cells, Cultured; Choline; Chromatography, High Pressure Liquid; Coronary Vessels; Endothelial Cells; Enzyme Inhibitors; Ethanolamines; Glycerophospholipids; Humans; Hydrolysis; Organophosphonates; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Stimulation, Chemical; Thrombin

2003