Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and chlorpheniramine

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with chlorpheniramine in 14 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(chlorpheniramine)
Trials
(chlorpheniramine)
Recent Studies (post-2010) (chlorpheniramine)
9,1561875522,040287240

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)chlorpheniramine (IC50)
Histamine H1 receptorHomo sapiens (human)0.066
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.1

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Q1
Juhlin, L; Pihl-Lundin, I1
Cunningham, FM; Foster, AP; Lees, P1
Cordeiro, RS; Watson, ML; Weg, VB; Williams, TJ1
Capron, A; Capron, M; De Vos, C; Joseph, M; Leprevost, C; Tomassini, M; Vorng, H1
Abraham, WM; Garrido, R; Stevenson, JS1
Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S1
Leff, AR; Munoz, NM; Popovich, KJ; Shioya, T; Stimler-Gerard, NP; White, SR1
Capron, A; Capron, M; De Vos, C; Leprevost, C; Tomassini, M1
Patterson, R; Rubin, AH; Smith, LJ1
Okamoto, M; Terao, M; Tokumura, A; Tsukatani, H; Yoshida, K1
Cutcher, A; Dunn, AM; Halonen, M; Holmes, T; Palmer, JD; Smith, PF1
Dunn, AM; Halonen, M; Lohman, IC; McManus, LM; Palmer, JD1
Halonen, M; Lohman, IC1

Trials

1 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and chlorpheniramine

ArticleYear
[Effects of inhaled aerosol of platelet activating factor on pulmonary function and airway responsiveness in normal subjects].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1992, Volume: 15, Issue:4

    Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Chlorpheniramine; Double-Blind Method; Humans; Lung; Male; Methacholine Chloride; Platelet Activating Factor; Respiratory Function Tests

1992

Other Studies

13 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and chlorpheniramine

ArticleYear
Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:3

    Topics: Adult; Aged; Chlorpheniramine; Chronic Disease; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Kallikreins; Loratadine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Skin; Urticaria

1992
Inflammatory effects of platelet activating factor (PAF) in equine skin.
    Equine veterinary journal, 1992, Volume: 24, Issue:3

    Topics: Animals; Capillary Permeability; Chlorpheniramine; Dermatitis; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Horse Diseases; Horses; Indomethacin; Injections, Intradermal; Leukocyte Count; Neutrophils; Platelet Activating Factor; Regional Blood Flow; Skin; Skin Temperature

1992
Histamine, leukotriene D4 and platelet-activating factor in guinea pig passive cutaneous anaphylaxis.
    European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2

    Topics: Acetophenones; Animals; Autacoids; Azepines; Blood Proteins; Bradykinin; Capillary Permeability; Chlorpheniramine; Cimetidine; Guinea Pigs; Histamine; Male; Methysergide; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; SRS-A; Tetrazoles; Triazoles

1991
Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine.
    International archives of allergy and applied immunology, 1989, Volume: 88, Issue:1-2

    Topics: Blood Platelets; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Cytotoxicity, Immunologic; Eosinophils; Humans; Hydroxyzine; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor

1989
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles

1989
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin

1985
Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:2

    Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Platelet Activating Factor; Reference Values; Trachea

1987
Inhibition of eosinophil chemotaxis by a new antiallergic compound (cetirizine).
    International archives of allergy and applied immunology, 1988, Volume: 87, Issue:1

    Topics: Cell Survival; Cells, Cultured; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Eosinophils; Exocytosis; Humans; Hydroxyzine; In Vitro Techniques; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor

1988
Mechanism of platelet activating factor-induced bronchoconstriction in humans.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Dose-Response Relationship, Drug; Humans; Indomethacin; Platelet Activating Factor; Respiratory Function Tests

1988
Study of platelet activating factor and its antagonists on rat colon strip with a new method avoiding tachyphylaxis.
    European journal of pharmacology, 1988, Apr-13, Volume: 148, Issue:3

    Topics: Animals; Atropine; Chlorpheniramine; Chromones; Colon; In Vitro Techniques; Indomethacin; Male; Methysergide; Muscle Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serum Albumin; SRS-A; Tachyphylaxis

1988
The responsiveness of rabbit bronchial rings to antigen, AGEPC and histamine.
    Immunopharmacology, 1986, Volume: 12, Issue:2

    Topics: Animals; Antigens; Atropine; Bronchi; Carbachol; Chlorpheniramine; Female; Histamine; Immunoglobulin E; Immunoglobulin G; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rabbits

1986
Participation of platelets in the physiologic alterations of the AGEPC response and of IgE anaphylaxis in the rabbit. Effects of PGI2 inhibition of platelet function.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: Anaphylaxis; Animals; Antigens; Blood Platelets; Chlorpheniramine; Epoprostenol; Female; Immunoglobulin E; Male; Platelet Activating Factor; Rabbits

1985
The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit.
    The American review of respiratory disease, 1993, Volume: 147, Issue:5

    Topics: Airway Resistance; Anaphylaxis; Animals; Azepines; Basophil Degranulation Test; Blood Pressure; Chlorpheniramine; Cimetidine; Histamine; Immunoglobulin E; Leukocyte Count; Lung Compliance; Platelet Activating Factor; Rabbits; Serotonin; Tidal Volume; Triazoles

1993