Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and capsaicin

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with capsaicin in 29 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(capsaicin)
Trials
(capsaicin)
Recent Studies (post-2010) (capsaicin)
9,15618755211,2386613,410

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.34)18.7374
1990's22 (75.86)18.2507
2000's3 (10.34)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hess, HJ; Kanai, Y; Lowe, JA; Nagahisa, A; Suga, O; Taniguchi, K; Tsuchiya, M1
Alving, K; Lundberg, JM; Matran, R1
Erjefält, I; Luts, A; Persson, CG; Sundler, F1
Coyle, AJ; Manzini, S; McKenniff, MG; Page, CP; Perretti, F; Seeds, EA; Spina, D; Tramontana, M1
Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Yamaguchi, T1
Krell, RD; McCarthy, M1
Esplugues, JV; Pique, JM; Whittle, BJ1
Barnes, PJ; Chung, KF; McCusker, MT; Roberts, NM1
Fujii, T; Morimoto, H; Senoh, H1
Esplugues, JV; Moncada, S; Whittle, BJ1
Bertrand, C; Daffonchio, L; Geppetti, P; Huber, O; Nadel, JA; Omini, C; Yamawaki, I1
Abelli, L; Evangelista, S; Manzini, S; Page, CP; Perretti, F; Seeds, EA1
McDonald, DM; Sulakvelidze, I1
Davison, JS; Mathison, R1
Inoue, H; Koshihara, Y; Nagata, N1
Bindi, D; Franchi-Micheli, S; Gentilini, G; Mugnai, S; Zilletti, L1
Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF1
Bertrand, C; Desai, MC; Geppetti, P; Nadel, JA; Piedimonte, G; Snider, RM1
Manzini, S; Perretti, F1
Eliakim, R; Karmeli, F; Okon, E; Rachmilewitz, D1
Manzini, S; Meini, S; Perretti, F1
Asano, M; Ishikawa, J; Saitoh, C1
Church, MK; Petersen, LJ; Skov, PS1
Alger, LE; Carson, SS; Garland, A; Leff, AR; McAllister, K; Necheles, J; Neeley, SP; Solway, J; White, SR1
Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG1
Choi, SY; Ha, H; Kim, KT1
Ashton, D; Fransen, JF; Hens, KA; Heylen, L; Hillen, LC; Janssens, F; Jurzak, MR; Leysen, JE; Mahieu, M; Megens, AA; Vermeire, JC; Vermote, PC1
Behar, J; Biancani, P; Cao, W; Cheng, L; de la Monte, S; Harnett, KM; Hong, J; Ma, J; Tong, M1
Behar, J; Biancani, P; Cao, W; Harnett, KM; Ma, J1

Reviews

1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and capsaicin

ArticleYear
Interactions between sensory neuropeptides and lipid mediators in the airways.
    Journal of lipid mediators, 1993, Volume: 8, Issue:2

    Topics: Animals; Bronchi; Capsaicin; Eicosanoids; Humans; Lung; Neurons, Afferent; Neuropeptides; Platelet Activating Factor; Tachykinins

1993

Other Studies

28 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and capsaicin

ArticleYear
Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Capillary Permeability; Capsaicin; Guinea Pigs; Histamine; Male; Mice; Muscle Contraction; Platelet Activating Factor; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Skin; SRS-A; Tachykinins; Ureter

1992
Effect of nedocromil sodium on allergen-, PAF-, histamine- and bradykinin-induced airways vasodilatation and pulmonary obstruction in the pig.
    British journal of pharmacology, 1991, Volume: 104, Issue:2

    Topics: Allergens; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bronchi; Capsaicin; Histamine Antagonists; Lung Diseases, Obstructive; Nedocromil; Nose; Platelet Activating Factor; Quinolones; Regional Blood Flow; Swine; Vasodilation

1991
The airway epithelial lining in guinea pigs is intact promptly after the mucosal crossing of a large amount of plasma exudate.
    International archives of allergy and applied immunology, 1990, Volume: 91, Issue:4

    Topics: Animals; Bronchi; Bronchial Provocation Tests; Capsaicin; Dextrans; Epithelium; Exudates and Transudates; Fluorescein-5-isothiocyanate; Fluoresceins; Guinea Pigs; Male; Microscopy, Fluorescence; Mucous Membrane; Plasma; Platelet Activating Factor; Trachea

1990
Effect of capsaicin on PAF-induced bronchial hyperresponsiveness and pulmonary cell accumulation in the rabbit.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: Anesthesia; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Capsaicin; Histamine; Lung; Nerve Fibers; Platelet Activating Factor; Rabbits; Radioimmunoassay; Serum Albumin, Bovine

1991
Inhibition of neutral endopeptidase potentiates bronchial contraction induced by immune response in guinea pigs in vitro.
    The American review of respiratory disease, 1991, Volume: 144, Issue:3 Pt 1

    Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Glycopeptides; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Male; Neprilysin; Ovalbumin; Platelet Activating Factor; Serotonin; SRS-A; Thiorphan

1991
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan

1991
Influence of morphine or capsaicin pretreatment on rat gastric microcirculatory response to PAF.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Animals; Blood Pressure; Capsaicin; Female; Gastric Mucosa; Male; Microcirculation; Morphine; Naloxone; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow

1990
Effect of topical capsaicin on the cutaneous responses to inflammatory mediators and to antigen in man.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:6

    Topics: Administration, Topical; Adult; Allergens; Capsaicin; Dinoprostone; Double-Blind Method; Histamine Release; Humans; Hypersensitivity; Hypersensitivity, Immediate; Neuropeptides; Platelet Activating Factor

1989
Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:3

    Topics: Animals; Capsaicin; Carbachol; Edema; Histamine; Male; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Skin; Skin Physiological Phenomena; SRS-A; Substance P; Trachea

1989
Local opioid-sensitive afferent sensory neurones in the modulation of gastric damage induced by Paf.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Animals; Capsaicin; Infusions, Intra-Arterial; Male; Morphine; Narcotics; Neurons, Afferent; Platelet Activating Factor; Rats; Rats, Inbred Strains; Stomach Ulcer; Tetrodotoxin

1989
Levodropropizine reduces capsaicin- and substance P-induced plasma extravasation in the rat trachea.
    European journal of pharmacology, 1993, Oct-12, Volume: 243, Issue:1

    Topics: Animals; Antitussive Agents; Blood Pressure; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Heart Rate; In Vitro Techniques; Muscle Contraction; Peripheral Nervous System; Platelet Activating Factor; Propylene Glycols; Rats; Rats, Inbred F344; Substance P; Trachea; Urinary Bladder

1993
Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airway inflammation in guinea pigs.
    European journal of pharmacology, 1993, Nov-16, Volume: 249, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Albuterol; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Capsaicin; Dextrans; Dyspnea; Fluorescein-5-isothiocyanate; Guinea Pigs; Histamine; Leukocytes; Male; Ovalbumin; Platelet Activating Factor

1993
Anti-edema action of formoterol in rat trachea does not depend on capsaicin-sensitive sensory nerves.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Afferent Pathways; Animals; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Endothelium, Vascular; Ethanolamines; Formoterol Fumarate; Injections, Intravenous; Male; Platelet Activating Factor; Premedication; Rats; Rats, Inbred F344; Substance P; Trachea; Tracheal Diseases

1994
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections

1993
Inhibition by actinomycin D of neurogenic mouse ear oedema.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:3

    Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide

1995
GABA-mediated inhibition of the anaphylactic response in the guinea-pig trachea.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Anaphylaxis; Animals; beta-Alanine; Bronchial Hyperreactivity; Capsaicin; Drug Interactions; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine Release; Macrophage Activation; Macrophages, Alveolar; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Nipecotic Acids; Ovalbumin; Platelet Activating Factor; Proline; Receptors, GABA; Tetrodotoxin; Trachea

1995
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve

1993
A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1

    Topics: Animals; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertonic Solutions; Neurokinin A; Neurons, Afferent; Piperidines; Platelet Activating Factor; Rats; Rats, Inbred F344; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium Chloride; Stimulation, Chemical; Substance P; Trachea; Tracheal Diseases

1993
Activation of capsaicin-sensitive sensory fibers modulates PAF-induced bronchial hyperresponsiveness in anesthetized guinea pigs.
    The American review of respiratory disease, 1993, Volume: 148, Issue:4 Pt 1

    Topics: Anesthesia; Animals; Azepines; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Nerve Fibers; Platelet Activating Factor; Ruthenium Red; Serum Albumin, Bovine; Time Factors; Triazoles

1993
Ketotifen and nitroxides decrease capsaicin-augmented ethanol-induced gastric damage in rats.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Cyclic N-Oxides; Ethanol; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Ketotifen; Leukotriene B4; Leukotriene C4; Male; Mast Cells; Nerve Fibers; Platelet Activating Factor; Premedication; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Spin Labels; Stomach Ulcer

1995
Effect of YM934, a KATP channel opener, on airway hyperresponsiveness induced by platelet activating factor in guinea-pigs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Benzoxazines; Capsaicin; Cyclic N-Oxides; Glycopeptides; Guinea Pigs; Infusions, Intravenous; Injections, Intravenous; Male; Oxazines; Platelet Activating Factor; Potassium Channels; Rats; Respiratory Hypersensitivity

1997
Platelet-activating factor induces histamine release from human skin mast cells in vivo, which is reduced by local nerve blockade.
    The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:5

    Topics: Adult; Anesthetics, Local; Basophils; Capsaicin; Dose-Response Relationship, Drug; Female; Histamine Release; Humans; Male; Mast Cells; Mepivacaine; Microdialysis; Middle Aged; Nerve Block; Platelet Activating Factor; Skin

1997
Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Animals, Newborn; Asthma; Capsaicin; Cells, Cultured; Coculture Techniques; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Eosinophils; Ganglia, Spinal; Humans; Myelin Basic Protein; N-Formylmethionine Leucyl-Phenylalanine; Neurons; Platelet Activating Factor; Polylysine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic, Seasonal; Substance P; Tissue Extracts

1997
Effects of S-salbutamol on human isolated bronchus.
    Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:1

    Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor

1998
Capsaicin inhibits platelet-activating factor-induced cytosolic Ca2+ rise and superoxide production.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Oct-01, Volume: 165, Issue:7

    Topics: Apoptosis; Biological Transport; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Capsaicin; Cytosol; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Inflammation; Platelet Activating Factor; Superoxides; Thapsigargin; Type C Phospholipases; Up-Regulation

2000
Pharmacological profile of (2R-trans)-4-[1-[3,5-bis(trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an orally and centrally active neurokinin-1 receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Administration, Oral; Allergens; Animals; Butanols; Capsaicin; Cats; Dogs; Edema; Ferrets; Gerbillinae; Guinea Pigs; Histamine; Kinetics; Malates; Mice; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Platelet Activating Factor; Rabbits; Receptors, Neurokinin-1; Salivation; Substance P; Time Factors

2002
HCl-activated neural and epithelial vanilloid receptors (TRPV1) in cat esophageal mucosa.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cats; Diterpenes; Electric Stimulation; Epithelial Cells; Esophagus; Hydrochloric Acid; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Stimulation, Chemical; Submucous Plexus; Substance P; Tetrodotoxin; TRPV Cation Channels

2009
Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:2

    Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Esophagus; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Signal Transduction; TRPV Cation Channels

2010