1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with calcimycin in 404 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (calcimycin) | Trials (calcimycin) | Recent Studies (post-2010) (calcimycin) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 11,946 | 40 | 444 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | calcimycin (IC50) |
|---|---|---|---|
| XBP1 | Homo sapiens (human) | 1.41 | |
| DNA damage-inducible transcript 3 protein | Mus musculus (house mouse) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 164 (40.59) | 18.7374 |
| 1990's | 216 (53.47) | 18.2507 |
| 2000's | 21 (5.20) | 29.6817 |
| 2010's | 2 (0.50) | 24.3611 |
| 2020's | 1 (0.25) | 2.80 |
| Authors | Studies |
|---|---|
| Franzén, L; Gustafson, C; Kald, B; Sjödahl, R; Tagesson, C; Weström, B | 1 |
| Damtew, B; Spagnuolo, PJ | 1 |
| Heckenberger, R; Schrör, K | 1 |
| Cramer, R; Knowles, A; Menegazzi, R; Patriarca, P; Zabucchi, G | 1 |
| Bachelet, M; Barre, A; Chouaid, C; Havet, N; Housset, B; Masliah, J; Vargaftig, BB | 1 |
| Autore, G; Biondi, A; Capasso, F; Izzo, AA; Mascolo, N | 1 |
| Eliakim, R; Karmeli, F; Ligumsky, M; Rachmilewitz, D; Simon, P | 1 |
| Bennett, A; Capasso, F; Tavares, IA | 1 |
| Lee, TC; Snyder, F; Uemura, Y | 1 |
| Chavis, C; Crastes de Paulet, A; Damon, M; Godard, P; Radeau, T | 1 |
| Dailey, LA; Devlin, RB; Friedman, M; McKinnon, K; Noah, TL; Samet, JM; Yankaskas, JR | 1 |
| Adler, L; Caplan, MS; Hsueh, W; Kelly, A | 1 |
| Buerke, M; Suttorp, N; Tannert-Otto, S | 1 |
| Hayashi, M; Imai, Y; Naraba, H; Oh-ishi, S; Omura, S; Tomoda, H | 1 |
| Ichimaru, T; Tai, HH | 1 |
| Chilton, FH; Hubbard, WC; Schleimer, RP; Tomioka, K; Triggiani, M | 1 |
| Braquet, P; Broquet, C; Hirasawa, N; Levine, L; Matsushita, Y; Mue, S; Muramatsu, S; Takahagi, H; Watanabe, M; Watanabe, T | 1 |
| Tai, HH; Wang, C | 1 |
| Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
| Chilton, FH; Fonteh, AN; Triggiani, M | 1 |
| Hammond, GL; Nelson, PJ; Peyman, JA | 1 |
| Arnoux, B; Canaud, B; Chavis, C; Cristol, JP; Damon, M; Mion, C | 1 |
| Chao, W; Hanahan, DJ; Liu, H; Olson, MS | 2 |
| Dürr, U; Grimminger, F; Seeger, W | 1 |
| Furukawa, M; Kumazawa, T; Saito, K; Satouchi, K; Yamashita, T | 1 |
| Cardillo, R; DiMuzio, J; Post, TJ; Raible, DG; Schulman, ES | 1 |
| Han, E; Joseph, R | 1 |
| Balestrieri, C; Biancone, L; Camussi, G; Iorio, EL; Montrucchio, G; Servillo, L; Tetta, C; Turello, E | 1 |
| Befus, AD; Bissonnette, EY; Donigi-Gale, D; Hogaboam, CM; Shoupe, TS; Wallace, JL | 1 |
| Galli, C; Marangoni, F; Petroni, A | 1 |
| Kantorski, J; Tchórzewski, H | 1 |
| Johnson, JA; Smith, DM; Turner, RA | 1 |
| Beilin, LJ; Croft, KD; Moulton, C; Proudfoot, J | 1 |
| Chang, JY; Glaser, KB; Lock, YW | 1 |
| Harris, T; Stewart, AG | 1 |
| Hayashi, H; Ikizawa, K; Inoue, K; Kato, T; Kudo, I; Uda, H; Yanoshita, R | 1 |
| Kondo, M; Naito, Y; Takahashi, S; Tanigawa, T; Yoshida, N; Yoshikawa, T | 1 |
| Horii, T; Kobayashi, Y; Okuyama, H; Saito, K; Satouchi, K; Watanabe, S; Yoshida, Y | 1 |
| Chilton, FH; Goldman, D; Torphy, TJ; Undem, BJ | 1 |
| Fernandez-Gallardo, S; Garcia, C; Garcia, MC; Gijon, MA; Nieto, ML; Sanchez Crespo, M | 1 |
| Huang, SC; Misawa, M | 1 |
| Church, MK; Thomas, G | 1 |
| Chiu, MH; Huang, SC; Misawa, M | 1 |
| Arner, M; Högestätt, ED | 1 |
| Ikemura, T; Ino, M; Matsumoto, M; Miwa, M; Okamoto, Y; Saito, K; Sugatani, J; Suzuki, Y | 1 |
| Adler, L; Hageman, JR; Hickman, AR; Silver, RK | 1 |
| Benveniste, J; Bidault, J; Jurgens, P; Leyravaud, S; Ninio, E | 1 |
| Baldo, BA; Cooney, SJ; Smal, MA | 1 |
| Peskar, BA; Pritze, S; Simmet, T | 1 |
| Alessi, D; Bussolino, F; Camussi, G; Turello, E | 1 |
| Blair, IA; Christman, BW; Christman, JW; Gay, JC; Prakash, C | 1 |
| Blasevich, M; Caruso, D; Galli, C; Petroni, A; Visioli, F; Zancocchia, B | 1 |
| Cheng, NN; Fukuda, T; Sugiura, T; Waku, K | 1 |
| Ninio, E; Schindler, PW | 1 |
| Aarsman, AJ; Sturk, A; ten Cate, JW; van den Bosch, H | 1 |
| Fujita, M; Masuzawa, Y; Nakagawa, Y; Ojima-Uchiyama, A; Sugiura, T; Waku, K | 1 |
| Fang, J; Zheng, QY | 1 |
| Blasevich, M; Galli, C; Petroni, A; Visioli, F | 1 |
| Häyry, P; Mattila, P; Renkonen, R; Turunen, JP | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 2 |
| Bass, DA; Bauldry, SA; Wykle, RL | 1 |
| Levine, L | 3 |
| Chilton, FH; Cluzel, M; MacGlashan, DW; Rohde, CA; Undem, BJ | 1 |
| Gomez-Cambronero, J; Huang, CK; Johnson, G; Sha'afi, RI; Wang, E | 1 |
| Hashimoto, T; Ishii, H; Nawata, H; Umeda, F | 1 |
| Barden, A; Nies, AS; Sturm, M; Tunney, A; Vandongen, R | 1 |
| Di Marzo, V; Galadari, SH; Morris, HR | 1 |
| Fontán, PA; Geffner, JR; Isturiz, MA; Sordelli, DO | 1 |
| Boney, RS; Rosenbaum, JT; Samples, JR; Valone, FH | 1 |
| Chilton, FH; D'Souza, DM; Triggiani, M | 1 |
| Bohrer, A; Ferdman, B; Holtzman, MJ; Turk, J | 1 |
| Rui, YC; Zeng, GQ | 1 |
| Ezaki, M; Inoue, Y; Miwa, M; Nakamura, K; Tomita, T | 1 |
| Asmis, R; Jörg, A | 1 |
| Damais, C; Denizot, Y; Deryckx, S; Dinarello, CA; Dulioust, A; Salem, P; Thomas, Y; Vivier, E | 1 |
| McCulloch, RK; Vandongen, R | 1 |
| Salari, H; Wong, A | 1 |
| Clarke, FM; Cock, I; Orozco, C; Perkins, AV | 1 |
| Northover, AM | 3 |
| Hughes, KT; Lee, DY; Saito, K; Sugatani, J | 1 |
| Maraganore, JM; McIntyre, TM; Prescott, SM; Seeger, AR; Zimmerman, GA | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Blank, ML; Kawasaki, T; Snyder, F; Suga, K | 1 |
| Fleisher, LN; Joyce, PB; Olson, NC | 2 |
| Champeix, P; Favier, R; Hurtaud, MF; Kaplan, C; Lecompte, T; Morel, MC; Potevin, F; Samama, M; Schlegel, N | 1 |
| Chilton, FH; Connell, TR; Triggiani, M | 1 |
| Fukuda, T; Masuzawa, Y; Sugiura, T; Waku, K | 1 |
| Christophers, E; Morita, E; Schröder, JM | 2 |
| Chavis, C; Crastes de Paulet, A; Damon, M; Godard, PH; Michel, FB; Radeau, T | 1 |
| Lim, WH; Stewart, AG | 1 |
| Edwards, RJ; MacDermot, J; Storch, J | 1 |
| Arm, JP; Burke, LA; Crea, AE; Lee, TH; Spur, BW; Wilkinson, JR | 1 |
| Hirst, JJ; Jenkin, G; Rice, GE; Thorburn, GD | 1 |
| Huang, TF; Ko, FN; Liu, YM; Sheu, SJ; Teng, CM | 1 |
| Dubbin, PN; Dusting, GJ; Harris, T; Stewart, AG | 2 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Hagenlocker, BE; Walker, BA; Ward, PA | 1 |
| Hecker, G; Ney, P; Schrör, K | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Asmis, R; Dennis, EA; Glaser, KB | 1 |
| Borgeat, P; Laviolette, M; Ménard, L; Naccache, PH; Pilote, S | 1 |
| Austen, KF; Benincaso, AI; Coblyn, JS; Larkin, JK; Sperling, RI; Weinblatt, ME | 1 |
| Tai, HH; Tanizawa, H | 1 |
| Beilin, LJ; Croft, KD; Masarei, J; Rouse, I; Vandongen, R | 1 |
| Bonak, VA; Caon, AC; Gaudry, M; Gilbert, C; Huang, CK; McColl, SR; Naccache, PH; Umezawa, K | 1 |
| Clay, KL; Henson, JE; Henson, PM; Riches, DW; Seccombe, JF; Young, SK | 1 |
| Hirafuji, M; Ogura, Y | 1 |
| Benveniste, J; Denizot, Y; Dubertret, L; Heslan, M; Jean-Louis, F; Michel, L; Thomas, Y | 1 |
| Champion, A; Cromwell, O; Kay, AB; Moqbel, R; Osei, D; Wardlaw, AJ | 1 |
| Austen, KF; Lewis, RA; Robin, JL | 1 |
| Johnson, HM; Torres, BA | 1 |
| Cox, CP | 2 |
| Benveniste, J; Chignard, M; Coëffier, E | 1 |
| Di Marzo, V; Morris, HR; Tippins, JR | 2 |
| Coutts, S; Jones, H; Khandwala, A; Neiss, E; Pruss, T; Weinryb, I | 1 |
| Kurosawa, M | 1 |
| Belch, JJ; Forbes, CD; Saniabadi, AR | 1 |
| Frick, KK; Scher, CD; Womer, RB | 1 |
| Melder, DC; Olsen, RA; Powis, G; Schlager, JJ; Seewald, MJ | 1 |
| DeCandido, S; Hassid, A; Satriano, JA; Schlondorff, D; Singhal, P | 1 |
| Ito, Y; Kametani, F; Kitagawa, S; Oda, Y | 1 |
| Chao, W; Hanahan, DJ; Olson, MS; Siafaka-Kapadai, A | 1 |
| Silbaugh, SA; Stengel, PW | 1 |
| Wey, HE | 1 |
| Dennis, EA; Glaser, KB; Lister, MD; Ulevitch, RJ | 1 |
| DiPersio, JF; Gasson, JC; Kaufman, SE | 1 |
| Mitchell, MD; Weinreb, RN | 1 |
| Gaskell, SJ; Haroldsen, PE | 1 |
| Houben, A; Lenoir, G; Remacle, J; Remy, E; Vandesteene, C | 1 |
| Chap, H; Record, M; Ribbes, G; Tercé, F | 1 |
| Jandrot-Perrus, M; Touqui, L; Vargaftig, BB | 1 |
| Prins, A; Schaap, MC; Sturk, A; ten Cate, JW; van den Bosch, H | 1 |
| Masuzawa, Y; Ojima-Uchiyama, A; Sugiura, T; Waku, K | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| de la Motte, CA; DiCorleto, PE | 1 |
| Emery, D; Margolskee, D; Nadel, JA; Ueki, IF; Widdicombe, JH; Yergey, J | 1 |
| Gudgeon, JR; Martin, W | 1 |
| Kariya, T; Kume, S; Matsumoto, Y; Ozaki, Y; Yatomi, Y | 1 |
| Franson, RC; Rosenthal, MD; Vishwanath, BS | 1 |
| Borgeat, P; DiPersio, JF; Kreis, C; McColl, SR; Naccache, PH | 1 |
| O'Flaherty, JT; Tessner, TG; Wykle, RL | 1 |
| Kownatzki, E; Neumann, M | 1 |
| Errasfa, M; Maridonneau-Parini, I; Russo-Marie, F | 1 |
| Moore, JN; Morris, DD | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kok, PT; Kreukniet, J; Warringa, RA | 1 |
| Bachelet, M; Béréziat, G; Kadiri, C; Masliah, J; Vargaftig, BB | 1 |
| Kobayashi, K; Mizoguchi, Y; Morisawa, S; Sakagami, Y; Seki, S; Yamamoto, S | 1 |
| Phillips, WA; Stewart, AG | 1 |
| Chilton, FH; Cluzel, M; Undem, BJ | 1 |
| Franson, RC; Rosenthal, MD | 1 |
| Stewart, AG | 1 |
| Bian, RL; Hong, JL; Zhou, HL | 1 |
| Chilton, FH; Triggiani, M | 1 |
| Henderson, WR; Martin, TR; Merritt, TL; Raugi, G | 1 |
| Dale, MM; Penfield, A | 1 |
| Hanahan, DJ; Olson, MS; Saito, K; Steinhelper, ME; Sugatani, J | 1 |
| Arichi, S; Kimura, Y; Okuda, H | 1 |
| Austen, KF; Kylander, KA; Lee, TH; Lewis, RA; Robin, JL; Sperling, RI | 1 |
| Nieto, ML; Sanchez Crespo, M; Velasco, S | 1 |
| Downes, CP; Huang, SJ; Monk, PN; Whetton, AD | 1 |
| Bienvenu, P; Braquet, M; Ducousso, R; Gerasimo, P; Kergonou, JF; Lavaud, P; Mathieu, J | 1 |
| Antoniw, JW; Piper, PJ; Stanton, AW | 1 |
| Lerner, R; Lindström, P; Palmblad, J | 1 |
| Grinstein, S; Nasmith, PE | 1 |
| Browne, PC; Detwiler, TC; Miller, JJ | 1 |
| Bussolino, F; Camussi, G; Gremo, F; Pescarmona, G | 1 |
| Errasfa, M; Fradin, A; Poincelot-Canton, B; Rothhut, B; Russo-Marie, F | 1 |
| Agrawal, DK; Tamura, N; Townley, RG | 1 |
| Dusting, GJ; Stewart, AG | 1 |
| Bussolino, F; Camussi, G; Gremo, F; Pescarmona, GP; Tetta, C | 2 |
| Dray, F; Fafeur, V; Junier, MP; Rougeot, C; Tiberghien, C | 1 |
| Eliakim, R; Karmeli, F; Rachmilewitz, D; Razin, E | 1 |
| Asyee, GM; Schaap, MC; Sturk, A; ten Cate, JW; van Maanen, M | 1 |
| Benhamou, M; Bessou, G; Hieblot, C; Liu, FT; Mencia-Huerta, JM; Ninio, E; Pitton, C; Salem, P | 1 |
| Bühler, FR; Dimitrov, D; Resink, TJ; Stucki, S | 1 |
| Bachelet, M; Errasfa, M; Russo-Marie, F | 1 |
| O'Flaherty, JT | 1 |
| Hardisty, RM; Pannocchia, A | 1 |
| Loeb, AL; Peach, MJ; Singer, HA | 1 |
| Bruynzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 2 |
| Pickett, WC; Ramesha, CS | 3 |
| Kikawa, Y; Shigematsu, Y; Sudo, M | 1 |
| Bodmer, JL; Bray, MA; McKearn-Smith, C; Metz-Virca, G; Virca, GD | 1 |
| McIntyre, TM; Prescott, SM; Sisson, JH; Zimmerman, GA | 1 |
| Molski, TF; Sha'afi, RI | 1 |
| Fuse, I; Hanano, M; Hattori, A; Higashihara, M; Koike, T; Nagayama, R; Shibata, A; Takahashi, H; Takeshige, T; Takizawa, S | 1 |
| Billah, MM; Eckel, S; Myers, RF; Siegel, MI | 1 |
| Clay, KL; Goldwasser, P; Neuwirth, R; Satriano, JA; Schlondorff, D | 1 |
| Piper, PJ; Stewart, AG | 1 |
| Henson, PM; Lynch, JM | 1 |
| Alam, I; Silver, MJ | 1 |
| Fest, W; Söling, HD | 1 |
| O'Flaherty, JT; Redman, J; Samuel, M; Thomas, M; Wykle, RL | 1 |
| DeCandido, S; Satriano, JA; Schlondorff, D | 1 |
| Purdon, AD; Smith, JB; Smith, S; Yang, DC | 1 |
| Hanahan, DJ; Homma, H; Kumar, R | 1 |
| Esterbauer, H; Hurst, JS; Juergens, G; Lang, J; Slater, TF; Zollner, H | 1 |
| Clay, KL; Haroldsen, PE; Murphy, RC | 1 |
| Billah, MM; Musch, MW; Siegel, MI | 1 |
| Dumarey, C; Jacquemin, C; Shaw, AM; Touqui, L; Vargaftig, BB | 1 |
| Chen, WY; Ko, WC; Ouyang, CH; Teng, CM | 1 |
| Lianos, EA; Zanglis, A | 1 |
| Oda, M; Saito, K; Satouchi, K | 1 |
| Aarhus, LL; Shimokawa, H; Vanhoutte, PM | 1 |
| Bruijnzeel, PL; Hamelink, ML; Kijne, AM; Kok, PT; Verhagen, J | 1 |
| Dabiri, GA; Shalit, M; Southwick, FS | 1 |
| Braquet, P; Neuwirth, R; Satriano, JA; Schlondorff, D; Singhal, P | 1 |
| Hirafuji, M; Nave, JF | 1 |
| Bochner, BS; Brown, KE; Peachell, PT; Schleimer, RP | 1 |
| Maclouf, J; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Bimmler, M; Donath, E; Egger, M; Glaser, R; Spangenberg, P; Till, U | 1 |
| Oda, M; Saito, K; Satouchi, K; Yasunaga, K | 3 |
| Ardaillou, N; Ardaillou, R; Hagege, J; Nivez, MP; Schlondorff, D | 1 |
| Billah, MM; Bryant, RW; Siegel, MI | 1 |
| Ma, YH; Ouyang, CH; Teng, CM | 1 |
| Hirai, A; Saito, H; Tamura, Y; Yoshida, S | 1 |
| Benveniste, J; Chignard, M | 1 |
| Brooks, DP; Chesney, CM; Crofton, JT; Huch, KM; Pifer, DD; Share, L | 1 |
| Benveniste, J; Chap, H; Douste-Blazy, L; Fontan, P; Ninio, E; Record, M; Ribbes, G | 1 |
| Anceschi, MM; Ban, C; Billah, MM; Bleasdale, JE; Di Renzo, GC; Hoffman, DR; Johnston, JM; Truong, CT | 1 |
| Landolfi, R; Motola, NC; Steiner, M; Turcotte, JG | 1 |
| Lefer, AM; Lefer, DJ; Roth, DM; Smith, JB | 1 |
| Kakkar, VV; Krishnamurthi, S; Westwick, J | 1 |
| Benveniste, J; Bidault, J; Burtin, C; Gubler, MC; Pirotzky, E | 1 |
| Alonso, F; Gómez-Cambronero, J; Iñarrea, P; Sánchez Crespo, M | 1 |
| Ehrlich, YH; Kornecki, E; Lenox, RH | 1 |
| Aglietta, M; Bussolino, F; Camussi, G; Coda, R; Piacibello, W; Tetta, C | 1 |
| Lees, CJ; McCall, CE; O'Flaherty, JT; Shewmake, T; Thomas, MJ; Wykle, RL | 1 |
| Hammett, MJ; Love, SH; McCall, CE; O'Flaherty, JT; Shewmake, TB; Thomas, MJ; Wykle, RL | 1 |
| Austen, KF; Lewis, RA; Mencia-Huerta, JM; Razin, E | 1 |
| Emilsson, A; Sundler, R | 1 |
| Albert, DH; Snyder, F | 2 |
| Carroll, C; Hammett, MJ; McCall, CE; O'Flaherty, JT; Thomas, MJ; Wykle, RL | 1 |
| Inada, Y; Nishikawa, K; Nomura, H; Terashita, Z; Tsushima, S; Yoshioka, Y | 1 |
| Benveniste, J; Mencia-Huerta, JM; Ninio, E | 1 |
| Mueller, HW; O'Flaherty, JT; Wykle, RL | 1 |
| Alam, I; Silver, MJ; Smith, JB | 1 |
| Chilton, FH; Ellis, JM; O'Flaherty, JT; Swendsen, CL; Wykle, RL | 1 |
| Ostermann, G; Thielmann, K; Till, U | 1 |
| Keenan, JP; Machin, SJ; McVerry, BA | 1 |
| Aglietta, M; Bussolino, F; Camussi, G; Malavasi, F; Piacibello, W; Sanavio, F; Tetta, C | 1 |
| Billah, MM; Siegel, MI | 1 |
| Lee, T; Lenihan, DJ; Malone, B; Roddy, LL; Wasserman, SI | 1 |
| White, GC | 1 |
| Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Nina, M; Packham, MA | 1 |
| Andres, JL; Clay, KL; Henson, PM; Lynch, J; Murphy, RC | 1 |
| McCall, CE; O'Flaherty, JT; Schmitt, JD; Wykle, RL | 1 |
| Chilton, FH; Ellis, JM; Olson, SC; Wykle, RL | 1 |
| Block, HU; Ostermann, G; Till, U | 1 |
| Benveniste, J; Boullet, C; Misumi, J; Pirotzky, E | 1 |
| Benveniste, J; Chignard, M; Le Couedic, JP; Vargaftig, BB | 2 |
| Arnoux, B; Benveniste, J; Duval, D | 1 |
| Lyons, RM; Shaw, JO | 1 |
| Chilton, FH; DeChatelet, LR; O'Flaherty, JT; Thomas, MJ; Waite, BM; Walsh, CE; Wykle, RL | 1 |
| Arnoux, B; Benveniste, J; Durand, J; Rigaud, M; Vargaftig, BB | 1 |
| Benveniste, J; Landes, A; Mencia-Huerta, JM; Roubin, R | 1 |
| Fitzgerald, V; Lee, TC; Malone, B; Snyder, F; Wasserman, SI | 1 |
| Czarneztki, BM | 1 |
| Akutsu, I; Fukuda, T; Makino, S; Motojima, S; Numao, T; Toda, M | 1 |
| Au, BT; Collins, PD; Williams, TJ | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Ishibashi, T; Koyama, Y; Nishihira, J; Takagi, S | 1 |
| Lu, JS; Zhang, LZ; Zhang, M | 1 |
| Binder, BR; Gajdzik, L; Graf, J; Maier, M; Tschugguel, W; Zhegu, Z | 1 |
| Bendele, AM; Cockerham, SL; Silbaugh, SA; Stengel, PW | 1 |
| Colotta, F; Fadlon, EJ; Mantovani, A; Matteucci, C; Orlando, S; Sozzani, S | 1 |
| Anderson, J; Shamsuddin, M; Smith, LJ | 1 |
| Bates, PJ; Brutinel, WM; Kreofsky, TJ; Limper, AH; Rohrbach, MS; Specks, U | 1 |
| Belogi, L; Cavallo, G; Cifone, MG; Croce, C; Guida, G; Mainiero, F; Santiangeli, C; Santoni, A; Tubaro, E | 1 |
| Egido, J; González, E; Gutierrez, S; Herrero-Beaumont, G; Miguelez, R; Palacios, I; Zarco, P | 1 |
| Mita, H; Shida, T | 1 |
| Lai, KN; Leung, JC; Lockwood, CM; Rifkin, I | 1 |
| Dai, FP; Liu, BJ; Zhang, SZ; Zheng, MR | 1 |
| Northover, AM; Northover, BJ | 1 |
| Kunievsky, B; Yavin, E | 1 |
| Berger, F; Borchard, U; Hafner, D; Weis, T | 1 |
| Aragonés, MD; Catalán, RE; Garde, E; Hernández, F; Lombardía, M; Martínez, AM | 1 |
| Hu, JH; Lin, AY; Rui, YC; Sun, DX; Zeng, GQ | 1 |
| Adams, J; Borgeat, P; Dinallo, RM; Farina, PR; Graham, AG; Hansen, G; Hoffman, AF; Miao, CK; Nadeau, M; Watrous, JM | 1 |
| Baldi, E; Forti, G; Gervasi, G; Krausz, C | 1 |
| Borgeat, P; Braquet, P; McColl, SR; McDonald, PP | 1 |
| Blasevich, M; Colombo, C; Galella, G; Galli, C; Papini, N; Petroni, A; Salami, M | 1 |
| Olson, MS; Zhou, W | 1 |
| Eda, R; Hopp, RJ; Townley, RG | 1 |
| de Boer, M; Koenderman, L; Kuijpers, TW; Mascart-Lemone, F; Roos, D; van Zwieten, R; Verhoeven, AJ | 1 |
| Evangelista, V; Locati, M; Luini, W; Mantovani, A; Sozzani, S; Zhou, D | 1 |
| Javors, MA; Olson, MS; Zhou, W | 1 |
| Kankaanranta, H; Kirkkola, AL; Moilanen, E; Nieminen, MM; Vapaatalo, H | 1 |
| Iwamoto, I; Kawashima, T; Nakagawa, N; Tomioka, H; Yoshida, S | 1 |
| Cheung, HT; Fu, SL; Smal, MA | 1 |
| Hakim, J; Pedruzzi, E; Périanin, A | 1 |
| Carloni, V; Gentilini, P; Laffi, G; Marra, F; Pinzani, M; Riccardi, D | 1 |
| Borgeat, P; Braquet, P; Palmantier, R; Sanchez, A; Surette, ME | 1 |
| Cabré, F; Carganico, G; Gutiérrez, M; Mauleón, D; Suesa, N; Tost, D; Ucedo, P | 1 |
| Akutagawa, H; Mayumi, M; Mikawa, H; Morita, M; Nambu, M; Ohshima, Y; Uenoyama, Y | 1 |
| Krämer, K; Markwitan, A; Pallauf, J | 1 |
| Elsner, J; Emmendörffer, A; Lohmann-Matthes, ML; Meier, B; Raeder, E; Roesler, J | 1 |
| Bowen, JG; Meats, JE; Steele, L | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Aprile, B; Buzzi, E; Leoncini, G | 1 |
| Nishino, K; Ohashi, M; Uno, T | 1 |
| Cissik, JH; Dalton, LM; McGlasson, DL; Patterson, WR | 1 |
| Franson, RC; Lattanzio, KS; Rosenthal, MD | 1 |
| Chilton, FH; Hubbard, WC; Sung, CM; Winkler, JD | 1 |
| Azzari, C; Baldi, E; Carloni, V; Gentilini, P; Gresele, P; Laffi, G; Marra, F; Rossi, ME | 1 |
| Chilton, FH; Fonteh, AN; Heravi, J; Torphy, TJ; Undem, BJ; Winkler, JD | 1 |
| Blair, IA; Christman, BW; Christman, JW; Dworski, R; Prakash, C | 1 |
| Cormier, Y; Israel-Assayag, E; Sirois, P; Tremblay, GM | 1 |
| Johnson, LW; Kruse-Elliott, KT; Olson, NC | 1 |
| Benveniste, J; el Azzouzi, B; Jurgens, P; Thomas, Y | 1 |
| Hsieh, KH; Ng, CK | 1 |
| Dewhirst, FE; Stashenko, P; Wucherpfennig, AL | 1 |
| Dodam, JR; Kruse-Elliott, KT; Olson, NC; Whorton, AR | 1 |
| Nieto, ML; Olson, SC; Venable, ME; Wykle, RL | 1 |
| Masuzawa, Y; Shikano, M; Yazawa, K | 1 |
| Boll, RM; Gustafson-Svärd, C; Kald, B; Tagesson, C | 1 |
| Huang, TG; Rui, YC; Sun, DX; Zeng, GQ | 1 |
| Baldi, E; Carloni, V; Casano, R; Falsetti, C; Forti, G; Gervasi, G; Krausz, C | 1 |
| Bryant, CM; Endemann, G; Feng, Y; Hamilton, GS; Liu, DY; Mewshaw, RE; Perumattam, J | 1 |
| Arnoux, A; Dulioust, A; Gregoir, C; Hilliquin, P; Menkés, CJ | 1 |
| Imaizumi, TA; Koyama, M; Satoh, K; Takamatsu, S; Yoshida, H | 1 |
| Akamatsu, H; Kanoh, T; Kurisaka, M; Niwa, Y; Ozaki, Y | 1 |
| Bado, A; Benveniste, J; Denizot, Y; Laboisse, C; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I | 1 |
| Clough, J; Cypcar, D; Kaplan, M; Lemanske, RF; Nagata, M; Sedgwick, J; Sorkness, R | 1 |
| Agrawal, DK; Miyagawa, H; Nabe, M; Sarmiento, EU; Townley, RG | 1 |
| Fukumura, M; Hirai, Y; Koide, K; Shindo, K; Sumitomo, M | 1 |
| Czarnetzki, BM; Hartmann, K; Pfrommer, C; Schwarz, S; Zuberbier, T | 1 |
| Clay, KL; Harrison, KA; Johnson, CA; Morelli, JG; Travers, JB | 1 |
| Kohno, S; Nabe, T; Yamamura, H | 1 |
| Ghosh, S; Rao, AK; Sun, L; Yang, X | 1 |
| Baskin, SI; Lempka, JC; Nealley, EW | 1 |
| Francescangeli, E; Goracci, G; Gresele, P; Mezzasoma, AM; Nenci, GG; Prosdocimi, M; Ribaldi, E | 1 |
| Hilger, RA; Köller, M; König, W | 2 |
| Anderson, R; Feldman, C; Theron, AJ | 1 |
| Ito, S; Komiyama, Y; Miwa, M; Sugatani, J | 1 |
| Kumagai, H; Nakayama, R; Saito, K; Tamaki, H; Yun, C | 1 |
| Kumagai, H; Nakayama, R; Udagawa, H | 1 |
| Balestrieri, ML; Lee, T; Servillo, L | 1 |
| Bolognese, BJ; Marshall, LA; Roshak, AK; Sung, CM; Winkler, JD | 1 |
| Martin, SL; Morse, DS; Stahl, GL | 1 |
| Ammit, AJ; O'Neill, C | 1 |
| Karasawa, K; Kudo, I; Murakami, M; Nakajima, K; Nojima, S; Samejima, Y; Setaka, M; Yanoshita, R | 1 |
| Clay, KL; Harrison, K; Johnson, C; Morelli, JG; Murphy, RC; Travers, JB; Zekman, T | 1 |
| Herrnreiter, A; Kasugai, H; Leff, AR; Muñoz, NM; Narahashi, T; Oyaizu, M; Saito, M; Sato, R | 1 |
| Inazu, T; Rezaul, K; Sada, K; Yamamura, H | 1 |
| Bazan, HE; Bazan, NG; DeCoster, MA; Tao, Y | 1 |
| Anderson, J; Chen, E; Shamsuddin, M; Smith, LJ | 1 |
| Denizot, Y; Dulery, C; Dupuis, F; Jean-Louis, F; Levasseur, S; Michel, L; Praloran, V | 1 |
| Fukumura, M; Koide, K; Shindo, K | 2 |
| Kobayashi, T; Oh-hashi, K; Okuyama, H; Takahashi, T; Watanabe, S | 1 |
| Botitsi, E; Mavri-Vavayanni, M; Siafaka-Kapadai, A | 1 |
| Hata, N; Kobayashi, T; Misawa, Y; Ohhashi, K; Okuyama, H; Takahashi, T; Watanabe, S | 1 |
| Ali, IQ; Gilani, AH; Nawaz, Z; Saeed, SA; Shah, BH; Virani, SS | 1 |
| Burstein, SH; Pestonjamasp, VK | 1 |
| Cardarelli, PM; Cobb, RR; Lazarides, E; Mastrangelo, M; Tsuruta, R | 1 |
| Barber, LA; Clay, KL; Hood, AF; Johnson, CA; Morelli, JG; Morin, SM; Murphy, RC; Pei, Y; Travers, JB; Williams, DA | 1 |
| Alexander, JS; Coe, L; Itoh, M; Okayama, N; Oshima, T | 1 |
| Chistov, IV; Dugina, TN; Glusa, E; Pinelis, VG; Storozhevykh, TP; Strukova, SM; Umarova, BA | 1 |
| Hichami, A; Legrand, AB; Martin-Chouly, CA; Menier, V; Noel, F; Pedrono, F; Youmine, H | 1 |
| Huo, LJ; Yang, ZM | 1 |
| Gabbeta, J; Kaplan, R; Mao, GF; Rao, AK; Sun, L | 1 |
| Cevallos, M; Gandhi, CR; Harvey, SA; Olson, MS | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Aydinok, Y; Coker, I; Hüseyinov, A; Kavakli, K; Nisli, G | 1 |
| Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J | 1 |
| Bayly, WM; Kingston, JK; Meyers, KM; Sellon, DC; Wardrop, KJ | 2 |
| Fonteh, AN | 1 |
| Baker, PR; Daniel, LW; Nixon, AB; O'Flaherty, JT; Owen, JS; Thomas, L; Wooten, R; Wykle, RL | 1 |
| Nakagawa, Y; Sakamoto, H; Tosaki, T | 1 |
| Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG | 1 |
| Aksu, K; Doganavsargil, E; Huseyinov, A; Keser, G; Oksel, F; Pirildar, T; Terzioglu, E; Tunc, SE; Turk, T | 1 |
| Rasheed, H; Saeed, SA | 1 |
| Akisu, C; Akisu, M; Berdeli, A; Dagci, T; Kultursay, N; Yalaz, M | 1 |
| Aikawa, T; Hirose, T; Matsumoto, I; Shimada, T | 2 |
| Barbour, SE; Best, AM; Moores, J; Schenkein, HA; Shin, CR; Tew, JG | 1 |
| Bailey, SR; Cunningham, FM; Elliott, J; Menzies-Gow, NJ; Sepulveda, MF | 1 |
| Berry, KA; Henson, PM; Murphy, RC | 1 |
| Crystal, GJ; Eom, W; Hu, G; Kim, SJ; Saad, MM | 1 |
| Wang, HL; Wang, LC; Wei, JW | 1 |
| Baldo, BA; Smal, MA | 1 |
3 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and calcimycin
| Article | Year |
|---|---|
Role of paf-acether and related ether-lipid metabolism in platelets.
Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cyclic AMP; Glycerylphosphorylcholine; Histamine Release; Humans; Hydrolysis; Phospholipases A; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1985 |
A role for PAF-acether (platelet-activating factor) in platelet-dependent vascular diseases?
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Humans; Hypersensitivity; Kidney Diseases; Platelet Activating Factor; Rabbits; Vascular Diseases | 1985 |
Physiological action of PAF in yeast Saccharomyces cerevisiae.
Topics: Adenylyl Cyclases; Calcimycin; Cyclic AMP; Enzyme Inhibitors; Platelet Activating Factor; Saccharomyces cerevisiae | 1996 |
3 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and calcimycin
| Article | Year |
|---|---|
Platelet-activating factor production during hemodialysis: effect of BN 52021.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Amyloidosis; beta 2-Microglobulin; Biocompatible Materials; Blood Platelets; Calcimycin; Cellulose; Diterpenes; Double-Blind Method; Female; Ginkgolides; Humans; Hydroxyeicosatetraenoic Acids; Lactones; Leukopenia; Lipoxygenase; Lymphocyte Activation; Male; Membranes, Artificial; Middle Aged; Platelet Activating Factor; Platelet Activation; Random Allocation; Renal Dialysis | 1992 |
Biochemical perturbations of BW 91Y (3-deazaadenosine) on human neutrophil chemotactic potential and lipid metabolism.
Topics: Arachidonic Acids; Arthritis, Rheumatoid; Calcimycin; Chemotaxis, Leukocyte; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Leukotriene B4; Lipid Metabolism; Lipids; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Platelet Activating Factor; Tubercidin | 1991 |
The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx.
Topics: Adenosine Diphosphate; Antimalarials; Arachidonic Acid; Calcimycin; Calcium; Cinchona Alkaloids; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation Inhibitors; Reference Values; Signal Transduction | 1998 |
398 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and calcimycin
| Article | Year |
|---|---|
Platelet-activating factor (PAF-acether) formation in neonatal intestinal mucosa and in cultured intestinal epithelial cells.
Topics: Animals; Animals, Newborn; Calcimycin; Cells, Cultured; Colon; Epithelium; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 1992 |
Platelet activating factor amplifies human neutrophil adherence to bovine endothelial cells: evidence for a lipoxygenase dependent mechanism.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cattle; Cell Adhesion; Cell Communication; Cells, Cultured; Endothelium, Vascular; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Molecular Sequence Data; Neutrophils; Platelet Activating Factor; SRS-A | 1992 |
Inhibition of calcimycin-induced stimulation of cytosolic calcium in human PMN by a LTB4 receptor antagonist.
Topics: Arachidonate 5-Lipoxygenase; Benzopyrans; Calcimycin; Calcium; Cytosol; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Receptors, Immunologic; Receptors, Leukotriene B4 | 1992 |
A new, one-step assay on whole cell suspensions for peroxidase secretion by human neutrophils and eosinophils.
Topics: Calcimycin; Cell Separation; Eosinophil Peroxidase; Eosinophils; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Platelet Activating Factor; Reference Values; Spectrophotometry; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Modulation of arachidonic acid metabolism and cyclic AMP content of human alveolar macrophages.
Topics: Adult; Aged; Aged, 80 and over; Arachidonic Acid; Calcimycin; Cell Count; Cells, Cultured; Cyclic AMP; Cyclooxygenase Inhibitors; Female; Humans; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages, Alveolar; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic | 1992 |
Effects of senna and its active compounds rhein and rhein-anthrone on PAF formation by rat colon.
Topics: Animals; Anthracenes; Anthraquinones; Calcimycin; Colon; Male; Platelet Activating Factor; Rats; Rats, Wistar; Senna Extract | 1992 |
Cytokines and platelet-activating factor in human inflamed colonic mucosa.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Calcimycin; Colitis, Ulcerative; Colon; Crohn Disease; Humans; Imidazoles; Immunoglobulin E; Interleukin-1; Intestinal Mucosa; Mesalamine; Organ Culture Techniques; Platelet Activating Factor; Prednisolone; Sulfasalazine; Thiazoles | 1992 |
PAF formation by human gastrointestinal mucosa/submucosa in-vitro: release by ricinoleic acid, and inhibition by 5-aminosalicylic acid.
Topics: Aminosalicylic Acids; Calcimycin; Gastric Mucosa; Humans; In Vitro Techniques; Intestinal Mucosa; Mesalamine; Platelet Activating Factor; Ricinoleic Acids | 1992 |
A novel CoA-independent transacetylase produces the ethanolamine plasmalogen and acyl analogs of platelet-activating factor (PAF) with PAF as the acetate donor in HL-60 cells.
Topics: Acetates; Acetyltransferases; Arachidonic Acid; Calcimycin; Calcium; Cations, Divalent; Cell Membrane; Cells, Cultured; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Magnesium; Phenylmethylsulfonyl Fluoride; Phospholipids; Plasmalogens; Platelet Activating Factor; Substrate Specificity; Temperature | 1992 |
Enhanced esterification process of 5-hydroxyeicosatetraenoic acid (5-HETE) in PMN from asthmatic patients.
Topics: Adult; Asthma; Calcimycin; Cell Migration Inhibition; Chromatography, High Pressure Liquid; Esterification; Humans; Hydroxyeicosatetraenoic Acids; Middle Aged; Neutrophils; Platelet Activating Factor; Reference Values | 1992 |
Effect of ozone on platelet-activating factor production in phorbol-differentiated HL60 cells, a human bronchial epithelial cell line (BEAS S6), and primary human bronchial epithelial cells.
Topics: Bronchi; Calcimycin; Cell Differentiation; Cells, Cultured; Chromatography, Thin Layer; Epithelial Cells; Epithelium; Humans; Ozone; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Hypoxia increases stimulus-induced PAF production and release from human umbilical vein endothelial cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Calcimycin; Cell Hypoxia; Culture Media; Endothelium, Vascular; Humans; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Thrombin | 1992 |
Stimulation of PAF-synthesis in pulmonary artery endothelial cells by Staphylococcus aureus alpha-toxin.
Topics: Adenosine Triphosphate; Animals; Bacterial Toxins; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemolysin Proteins; Inflammation; Platelet Activating Factor; Pulmonary Artery; Staphylococcus aureus; Swine | 1992 |
Enhanced production of platelet-activating factor in stimulated rat leukocytes pretreated with triacsin C, A novel acyl-coA synthetase inhibitor.
Topics: Acylation; Animals; Calcimycin; Coenzyme A Ligases; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Repressor Proteins; Saccharomyces cerevisiae Proteins; Triazenes | 1992 |
Alteration of platelet activating factor (PAF) metabolism in rat pulmonary alveolar macrophages and plasma by cigarette smoking.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Animals; Blood Platelets; Body Weight; Bronchoalveolar Lavage Fluid; Calcimycin; Macrophages, Alveolar; Male; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tobacco Smoke Pollution | 1992 |
Characterization of platelet-activating factor synthesized by normal and granulocyte-macrophage colony-stimulating factor-primed human eosinophils.
Topics: Calcimycin; Cells, Cultured; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor | 1992 |
Preparation of immunoaffinity mini-columns for the analysis of platelet activating factor (PAF) in biological samples.
Topics: Animals; Calcimycin; Chromatography, Affinity; Immunochemistry; Immunoglobulin G; Macrophages; Platelet Activating Factor; Rabbits; Rats | 1992 |
A sensitive and specific radioimmunoassay for platelet-activating factor.
Topics: Animals; Calcimycin; Cross Reactions; Immunoglobulin G; Kinetics; Microchemistry; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipids; Platelet Activating Factor; Rabbits; Radioimmunoassay | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
Factors that influence the proportions of platelet-activating factor and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine synthesized by the mast cell.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Mast Cells; Mice; Mice, Inbred CBA; Phenylmethylsulfonyl Fluoride; Phosphorus; Platelet Activating Factor | 1992 |
HLA-DR genes are silenced in human trophoblasts and stimulation of signal transduction pathways does not circumvent interferon-gamma unresponsiveness.
Topics: Calcimycin; Cholera Toxin; Colforsin; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Interferon-gamma; Ionomycin; Placenta; Platelet Activating Factor; Pregnancy; Receptors, Immunologic; Receptors, Interferon; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Virulence Factors, Bordetella | 1992 |
Platelet-activating factor-stimulated protein tyrosine phosphorylation and eicosanoid synthesis in rat Kupffer cells. Evidence for calcium-dependent and protein kinase C-dependent and -independent pathways.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Down-Regulation; Egtazic Acid; Eicosanoids; Electrophoresis, Polyacrylamide Gel; Gallic Acid; Kupffer Cells; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Radioimmunoassay; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply.
Topics: Calcimycin; Chromatography, High Pressure Liquid; Fatty Acids, Nonesterified; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotrienes; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Platelet Activating Factor | 1992 |
Evidence of platelet-activating factor in nasal polyps.
Topics: Adolescent; Adult; Aged; Antibodies, Anti-Idiotypic; Calcimycin; Child; Chronic Disease; Female; Humans; Immunoglobulin E; Male; Middle Aged; Nasal Polyps; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Sinusitis | 1992 |
Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils.
Topics: Azepines; Calcimycin; Calcium; Cytosol; Dinoprostone; Eosinophils; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Lung; Mast Cells; Neutrophils; Piperidines; Platelet Activating Factor; Prostaglandin D2; Secretory Rate; SRS-A; Triazoles | 1992 |
Amyloid beta-protein fragment 25-35 causes activation of cytoplasmic calcium in neurons.
Topics: Aequorin; Amyloid beta-Peptides; Animals; Calcimycin; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Kinetics; Luminescent Measurements; Nerve Growth Factors; Neurons; PC12 Cells; Peptide Fragments; Platelet Activating Factor | 1992 |
Platelet-activating factor biosynthesis by cultured mesangial cells is modulated by proteinase inhibitors.
Topics: Acetyltransferases; Animals; Calcimycin; Cells, Cultured; Cytokines; Epithelial Cells; Epithelium; Glomerular Mesangium; Humans; Immunoglobulin G; Microspheres; Phagocytosis; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protease Inhibitors; Rats; Recombinant Proteins | 1992 |
Platelet-activating factor synthesis by peritoneal mast cells and its inhibition by two quinoline-based compounds.
Topics: Animals; Biological Assay; Calcimycin; Histamine; Lipoxygenase Inhibitors; Male; Mast Cells; Molecular Structure; Naphthaleneacetic Acids; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Quinolines; Rats; Rats, Inbred Strains | 1992 |
Modulation of arachidonic acid metabolism in cultured rat astroglial cells by long-chain N-3 fatty acids.
Topics: Animals; Arachidonic Acid; Astrocytes; Calcimycin; Cells, Cultured; Eicosanoids; Fatty Acids, Unsaturated; Platelet Activating Factor; Rats | 1992 |
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan | 1992 |
The effect of lipoproteins on the release of some eicosanoids by stimulated human leukocytes. A possible role in atherogenesis.
Topics: Arachidonic Acid; Calcimycin; Dextran Sulfate; Dinoprostone; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Lipoproteins, LDL; Platelet Activating Factor | 1991 |
PAF and LTB4 biosynthesis in the human neutrophil: effects of putative inhibitors of phospholipase A2 and specific inhibitors of 5-lipoxygenase.
Topics: Acetyltransferases; Calcimycin; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1991 |
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.
Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1991 |
Guinea pig bone marrow cells treated with platelet-activating factor generate factor(s) which affects their DNA synthesis and microbicidal activity.
Topics: Animals; Bone Marrow; Calcimycin; Candida; Cell Division; Cells, Cultured; DNA Replication; Female; Guinea Pigs; Hematopoietic Stem Cells; Kinetics; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thymidine | 1991 |
Role of platelet-activating factor (PAF) in superoxide production by human polymorphonuclear leukocytes.
Topics: Calcimycin; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Superoxides | 1991 |
Effect of dietary alpha-linolenate on platelet-activating factor production in rat peritoneal polymorphonuclear leukocytes.
Topics: alpha-Linolenic Acid; Animals; Calcimycin; Dietary Fats, Unsaturated; Inflammation; Leukotriene B4; Linolenic Acids; Male; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
Inhibition by adenosine 3':5'-monophosphate of eicosanoid and platelet-activating factor biosynthesis in the mouse PT-18 mast cell.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Eicosanoids; Kinetics; Leukotrienes; Mast Cells; Mice; Platelet Activating Factor; Prostaglandin D2; Theophylline | 1990 |
Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Acyltransferases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Coenzyme A Ligases; Fatty Acids; Humans; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Theophylline | 1990 |
The effect of platelet-activating factor on histamine release from rat peritoneal mast cells.
Topics: Aging; Animals; Ascitic Fluid; Buffers; Calcimycin; Calcium; Histamine Release; In Vitro Techniques; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
Platelet activating factor does not release histamine from human dispersed cutaneous mast cells.
Topics: Antibodies, Anti-Idiotypic; Biomarkers, Tumor; Blood Platelets; Calcimycin; Calcium; Cells, Cultured; Child; Child, Preschool; Energy Metabolism; Histamine; Histamine Release; Humans; Infant; Leukocytes; Lymphokines; Male; Mast Cells; Platelet Activating Factor; Skin; Substance P; Tumor Protein, Translationally-Controlled 1 | 1990 |
The effect of platelet-activating factor on histamine release from guinea pig peritoneal mast cells.
Topics: Animals; Calcimycin; Guinea Pigs; Histamine Release; In Vitro Techniques; Male; Mast Cells; Peritoneal Cavity; Phospholipid Ethers; Platelet Activating Factor; Serum Albumin, Bovine | 1991 |
Endothelium-dependent relaxation and effects of prostacyclin, endothelin and platelet-activating factor in human hand veins and arteries.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Arteries; Calcimycin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Epoprostenol; Female; Hand; Humans; Iloprost; Indomethacin; Male; Middle Aged; Platelet Activating Factor; Vasodilation; Veins | 1991 |
Release of newly synthesized platelet-activating factor (PAF) from human polymorphonuclear leukocytes under in vivo conditions. Contribution of PAF-releasing factor in serum.
Topics: Calcimycin; Cytokines; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1992 |
Anticardiolipin antibody-positive serum enhances endothelial cell platelet-activating factor production.
Topics: 6-Ketoprostaglandin F1 alpha; Antibodies; Antiphospholipid Syndrome; Calcimycin; Cardiolipins; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Platelet Activating Factor; Umbilical Veins | 1991 |
Cell adhesion by membrane-bound paf-acether.
Topics: Animals; Azepines; Calcimycin; Cell Adhesion; Diterpenes; Ginkgolides; Humans; In Vitro Techniques; Lactones; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Triazoles; Zymosan | 1991 |
Antibodies to platelet-activating factor (PAF) inhibit PAF-induced platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Antibodies; Calcimycin; Immunoglobulins; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sheep; Species Specificity | 1991 |
Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Calcimycin; Diterpenes; Eicosanoids; Ginkgolides; In Vitro Techniques; Lactones; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Circulation; Radioimmunoassay; SRS-A; Swine; Thromboxane B2; Triazoles | 1991 |
Role of platelet activating factor in the adhesion process of polymorphonuclear neutrophils to endothelial cells.
Topics: Angiotensin II; Calcimycin; Cell Adhesion; Endothelium, Vascular; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Thrombin | 1991 |
Analysis of effector cell-derived lyso platelet activating factor by electron capture negative ion mass spectrometry.
Topics: Adult; Animals; Calcimycin; Chromatography, Gas; Chromatography, Thin Layer; Electrochemistry; Glyceryl Ethers; Humans; In Vitro Techniques; Macrophages, Alveolar; Mass Spectrometry; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1991 |
Arachidonic acid cycloxygenase and lipoxygenase pathways are differently activated by platelet activating factor and the calcium-ionophore A23187 in a primary culture of astroglial cells.
Topics: Animals; Arachidonic Acid; Astrocytes; Calcimycin; Cells, Cultured; Diglycerides; Fatty Acids, Nonesterified; Hydrolysis; Lipoxygenase; Phospholipids; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats | 1991 |
Transient activation of 1-O-alkyl-sn-glycero-3-phosphocholine: acetyl-CoA acetyltransferase during the incubation of macrophages.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Biological Assay; Calcimycin; Cell-Free System; Enzyme Activation; Hot Temperature; Macrophages, Alveolar; Platelet Activating Factor; Rabbits | 1991 |
Kinetic studies of human and rat neutrophil lysoPAF acetyltransferase using lysoPAF and dansyllysoPAF as substrates.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Calcimycin; Dansyl Compounds; Fluorescent Dyes; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Rats; Substrate Specificity | 1991 |
Studies on the selectivity of enzymes involved in platelet-activating factor formation in stimulated cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetates; Acetyltransferases; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Humans; Kinetics; Lysophospholipase; Neutrophils; Phenylmethylsulfonyl Fluoride; Phospholipases A; Phospholipases A1; Phospholipases A2; Platelet Activating Factor; Thrombin | 1991 |
Regulation of the biosynthesis of platelet-activating factor in alveolar macrophages.
Topics: Acetyl Coenzyme A; Acetyltransferases; Calcimycin; Homeostasis; Ketone Bodies; Kinetics; Macrophages, Alveolar; Platelet Activating Factor | 1991 |
[Inhibitory effect of esculentoside A on platelet activating factor released from calcimycin induced rat peritoneal macrophages].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Macrophages; Male; Oleanolic Acid; Peritoneal Cavity; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Saponins | 1991 |
Arachidonic acid cyclo and lipoxygenase pathways in astroglial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Calcimycin; Cells, Cultured; Diglycerides; Eicosanoids; Fatty Acids, Nonesterified; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Platelet Activating Factor; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Thromboxane B2 | 1991 |
Second messenger pathways in lymphocyte binding and penetration through graft vascular endothelium.
Topics: Animals; Bucladesine; Calcimycin; Cell Communication; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Lymphocytes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Differential actions of diacyl- and alkylacylglycerols in priming phospholipase A2, 5-lipoxygenase and acetyltransferase activation in human neutrophils.
Topics: Acetyltransferases; Adult; Arachidonate 5-Lipoxygenase; Calcimycin; Chromatography, Thin Layer; Diglycerides; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Structure-Activity Relationship | 1991 |
Regulation of arachidonic acid metabolism by phenylarsine oxide.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Arsenicals; Bradykinin; Calcimycin; Cell Line; Epoprostenol; Kinetics; Liver; Lymphoma; Mice; Platelet Activating Factor; Rats | 1991 |
Dynamics of platelet-activating-factor release and uptake in a human neutrophil suspension.
Topics: Calcimycin; Humans; Kinetics; Models, Theoretical; Myocardium; Neutrophils; Platelet Activating Factor | 1991 |
Platelet-activating factor induces tyrosine phosphorylation in human neutrophils.
Topics: Autoradiography; Blotting, Western; Calcimycin; Calcium; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Humans; Neutrophils; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Substrate Specificity; Tyrosine; Virulence Factors, Bordetella | 1991 |
Increased intracellular calcium mobilization in platelets from patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Analysis of Variance; Blood Glucose; Blood Platelets; Calcimycin; Calcium; Calcium Chloride; Diabetes Mellitus, Type 2; Egtazic Acid; Female; Glycated Hemoglobin; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Reference Values; Thrombin | 1991 |
Release of platelet activating factor by the isolated kidney is not linked to the production of prostaglandins.
Topics: Angiotensin II; Animals; Bradykinin; Calcimycin; Dinoprostone; In Vitro Techniques; Kidney; Male; Perfusion; Platelet Activating Factor; Prostaglandins; Rats; Rats, Inbred Strains; Renal Veins; Stimulation, Chemical; Vascular Resistance | 1991 |
Novel interactions between second messengers in rat basophilic leukaemia (RBL-1) cells.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Leukemia, Basophilic, Acute; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Second Messenger Systems; SRS-A; Tumor Cells, Cultured; Type C Phospholipases | 1990 |
Neutrophil erythrotoxicity induced by phorbol myristate acetate: mechanisms involved in neutrophil activation.
Topics: Antigen-Antibody Complex; Calcimycin; Catalase; Cell Adhesion; Cell Survival; Chemotaxis; Dose-Response Relationship, Drug; Erythrocytes; Humans; Immunity, Cellular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Synthesis of platelet activating factor by ocular tissue from inflamed eyes.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Ciliary Body; Cornea; Endotoxins; Eye; Female; Inflammation; Iris; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Retina | 1991 |
Metabolism of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in the human neutrophil.
Topics: Calcimycin; Carbon Radioisotopes; Chromatography, Thin Layer; Humans; In Vitro Techniques; Kinetics; Models, Biological; Neutrophils; Phosphatidylcholines; Platelet Activating Factor; Radioisotope Dilution Technique; Tritium | 1991 |
Actions of vanadate on arachidonic acid metabolism by cells in culture.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acids; Calcimycin; Cattle; Cell Line; Cells, Cultured; Kinetics; Liver; Lyngbya Toxins; Muscle, Smooth, Vascular; Norepinephrine; Platelet Activating Factor; Rats; Serotonin; Vanadates | 1991 |
Synthesis of the 1-O-hexadecyl molecular species of platelet-activating factor by airway epithelial and vascular endothelial cells.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, Thin Layer; Endothelium, Vascular; Epithelium; Gas Chromatography-Mass Spectrometry; Humans; Mucous Membrane; Platelet Activating Factor; Sheep; Trachea | 1991 |
[Inhibitory effect of dauricine on platelet activating factor released from calcimycin-induced mouse peritoneal macrophages].
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcimycin; Dose-Response Relationship, Drug; Female; Isoquinolines; Macrophages; Male; Mice; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation Inhibitors; Tetrahydroisoquinolines | 1990 |
Rapid and reversible inhibition by low density lipoprotein of the endothelium-dependent relaxation to hemostatic substances in porcine coronary arteries. Heat and acid labile factors in low density lipoprotein mediate the inhibition.
Topics: Acids; Adenosine Diphosphate; Animals; Calcimycin; Coronary Vasospasm; Coronary Vessels; Endothelium, Vascular; Female; Hot Temperature; In Vitro Techniques; Lipoproteins, LDL; Male; Muscle Relaxation; Nitric Oxide; Platelet Activating Factor; Swine; Thrombin; Thrombosis | 1990 |
Calcium-ionophore-induced formation of platelet-activating factor and leukotrienes by horse eosinophils: a comparative study.
Topics: Animals; Buffers; Calcimycin; Calcium; Dose-Response Relationship, Drug; Eosinophils; Horses; Hydrogen-Ion Concentration; Ionomycin; Nigericin; Platelet Activating Factor; Rabbits; SRS-A | 1990 |
Immunoregulatory functions of paf-acether. IV. Enhancement of IL-1 production by muramyl dipeptide-stimulated monocytes.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Calcimycin; Dose-Response Relationship, Drug; Humans; Immunologic Techniques; In Vitro Techniques; Interleukin-1; Monocytes; Platelet Activating Factor; Secretory Rate | 1990 |
Mechanisms of platelet activating factor-induced aggregation and secretion in human platelets.
Topics: Adult; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; Kinetics; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane A2 | 1990 |
Generation of platelet activating factor (PAF) by a human lung epithelial cell line.
Topics: Animals; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Lung; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate | 1990 |
Partial characterization of the PAF-induced soluble factors which mimic the activity of 'early pregnancy factor'.
Topics: Animals; Biological Factors; Calcimycin; Chaperonin 10; Diethylcarbamazine; Masoprocol; Mice; Peptides; Platelet Activating Factor; Pregnancy Proteins; Solubility; Spleen; Stimulation, Chemical; Suppressor Factors, Immunologic; Vasodilator Agents | 1990 |
Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.
Topics: Aminoquinolines; Animals; Bradykinin; Calcimycin; Calcium; Cimetidine; Endothelium, Vascular; Guinea Pigs; Histamine; Histamine Antagonists; Isoproterenol; Platelet Activating Factor; Pyrilamine; Vena Cava, Inferior | 1990 |
Development of a novel scintillation proximity radioimmunoassay for platelet-activating factor measurement: comparison with bioassay and GC/MS techniques.
Topics: Animals; Antibody Specificity; Calcimycin; Cell Degranulation; Gas Chromatography-Mass Spectrometry; Humans; Lymphocyte Activation; Microspheres; Neutrophils; Platelet Activating Factor; Rabbits; Radioimmunoassay; Reproducibility of Results; Scintillation Counting; Silicates; Silicic Acid; Yttrium | 1990 |
Hirudin-based peptides block the inflammatory effects of thrombin on endothelial cells.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Hirudins; Humans; Inflammation; Kinetics; Peptide Fragments; Platelet Activating Factor; Thrombin | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
An arachidonoyl (polyenoic)-specific phospholipase A2 activity regulates the synthesis of platelet-activating factor in granulocytic HL-60 cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Fatty Acids, Unsaturated; Granulocytes; Humans; Lipoxygenase Inhibitors; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Tumor Cells, Cultured | 1990 |
Mono-hydroxyeicosatetraenoic acids during porcine endotoxemia. Effect of a platelet-activating factor receptor antagonist.
Topics: Animals; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Disease Models, Animal; Endotoxins; Escherichia coli; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Quinolines; Respiratory Distress Syndrome; Swine | 1990 |
Aequorin-detected calcium changes in stimulated thrombasthenic platelets. Aggregation-dependent calcium movement in response to ADP.
Topics: Adenosine Diphosphate; Aequorin; Blood Platelet Disorders; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; In Vitro Techniques; Luminescent Proteins; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin | 1990 |
Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor.
Topics: Acylation; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dietary Fats; Eicosapentaenoic Acid; Fish Oils; In Vitro Techniques; Mast Cells; Mice; Neutrophils; Phosphatidylcholines; Platelet Activating Factor | 1990 |
Ether lysophospholipid-induced production of platelet-activating factor in human polymorphonuclear leukocytes.
Topics: Acetates; Acetyl Coenzyme A; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Zymosan | 1990 |
Production of 15-hydroxyeicosatetraenoic acid by purified human eosinophils and neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Separation; Complement C5a; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1990 |
Enhanced arachidonic acid metabolism and human neutrophil migration in asthma.
Topics: Adolescent; Adult; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Asthma; Calcimycin; Chemotaxis, Leukocyte; Humans; Leukotrienes; Middle Aged; Neutrophils; Platelet Activating Factor | 1990 |
Macrophage activation reduces mobilization of arachidonic acid by guinea-pig and rat peritoneal macrophages in vitro.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Epoprostenol; Guinea Pigs; Macrophage Activation; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Zymosan | 1990 |
Thromboxane release by lymphokine-differentiated U937 human monocytic cells: response to platelet-activating factor (PAF) and chemotactic peptide (FMLP) but not to low affinity IGE-receptor (Fc epsilon RII/CD23) occupation.
Topics: Antibodies, Anti-Idiotypic; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Drug Synergism; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukemia, Monocytic, Acute; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Binding; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Comparison of the generation of platelet-activating factor and leukotriene C4 in human eosinophils stimulated by unopsonized zymosan and by the calcium ionophore A23187: the effects of nedocromil sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eosinophils; Humans; Nedocromil; Opsonin Proteins; Platelet Activating Factor; Platelet Aggregation; Quinolones; SRS-A; Stimulation, Chemical; Time Factors; Zymosan | 1990 |
Identification of a novel and highly potent eosinophil chemotactic lipid in human eosinophils treated with arachidonic acid.
Topics: Arachidonate 15-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Eosinophils; Glutathione; Humans; In Vitro Techniques; Leukotriene B4; Lipids; Magnesium; Platelet Activating Factor; Structure-Activity Relationship | 1990 |
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1990 |
Inhibition of rabbit platelet aggregation by 1,4-naphthoquinones.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Collagen; Naphthoquinones; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thrombin; Thromboxane A2 | 1990 |
Platelet-activating factor may act as a second messenger in the release of icosanoids and superoxide anions from leukocytes and endothelial cells.
Topics: Animals; Aorta; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Eicosanoids; Endothelium, Vascular; Endotoxins; Epoprostenol; Guinea Pigs; In Vitro Techniques; Kinetics; Leukocytes; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Platelet Activating Factor; Second Messenger Systems; Superoxides | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Superoxide responses of immune complex-stimulated rat alveolar macrophages. Intracellular calcium and priming.
Topics: Adenosine Triphosphate; Animals; Antigen-Antibody Complex; Calcimycin; Calcium; Complement C5a; Cytoplasm; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Rats; Superoxides | 1990 |
Cytotoxic enzyme release and oxygen centered radical formation in human neutrophils are selectively inhibited by E-type prostaglandins but not by PGI2.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cyclic AMP; Diterpenes; Epoprostenol; Free Radicals; Ginkgolides; Glucuronidase; Humans; In Vitro Techniques; Lactones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandins E; Superoxides | 1990 |
Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells.
Topics: Adenosine Diphosphate; Calcimycin; Calcium; Cell Line; Enzyme Activation; Epinephrine; Glycerophospholipids; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Bacterial lipopolysaccharide priming of P388D1 macrophage-like cells for enhanced arachidonic acid metabolism. Platelet-activating factor receptor activation and regulation of phospholipase A2.
Topics: Animals; Arachidonic Acids; Calcimycin; Cell Line; Dactinomycin; Diglycerides; Dinoprostone; Kinetics; Lipopolysaccharides; Macrophages; Models, Biological; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1990 |
Role of platelet-activating factor and eicosanoids during endotoxin-induced lung injury in pigs.
Topics: Animals; Body Water; Calcimycin; Capillary Permeability; Chromatography, High Pressure Liquid; Eicosanoids; Endotoxins; Escherichia coli; Heart; Leukotriene B4; Lung; Lung Diseases; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Quinolines; Swine | 1990 |
Inhibitory effects of MK-886 on arachidonic acid metabolism in human phagocytes.
Topics: Actins; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Survival; Chromatography, High Pressure Liquid; Colony-Stimulating Factors; Eosinophils; Humans; In Vitro Techniques; Indoles; Leukotriene Antagonists; Leukotrienes; Neutrophils; Phagocytes; Platelet Activating Factor; Superoxides | 1990 |
Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate.
Topics: Aged; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Calcimycin; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Methotrexate; Middle Aged; Neutrophils; Phospholipases; Platelet Activating Factor | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Regulation of platelet-activating factor receptor and PAF receptor-mediated arachidonic acid release by protein kinase C activation in rat Kupffer cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Enzyme Activation; Kinetics; Kupffer Cells; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1990 |
Leukocyte and platelet function and eicosanoid production in subjects with hypercholesterolaemia.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Leukotriene B4; Lipids; Luminescent Measurements; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1990 |
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
The subcellular distribution of platelet-activating factor in stimulated human neutrophils.
Topics: Calcimycin; Cell Compartmentation; Cell Fractionation; Cell Membrane; Humans; In Vitro Techniques; Intracellular Membranes; Microscopy, Electron; Neutrophils; Phagocytosis; Phagosomes; Platelet Activating Factor; Subcellular Fractions | 1990 |
Distinct stimulatory effect of platelet-activating factor on prostaglandin I2 and thromboxane A2 biosynthesis by rat dental pulp.
Topics: Animals; Calcimycin; Calcium; Dental Pulp; Epoprostenol; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Stimulation, Chemical; Thromboxane A2 | 1990 |
Production of paf-acether by human epidermal cells.
Topics: Acetyl Coenzyme A; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Epidermal Cells; Epidermis; Humans; Platelet Activating Factor | 1990 |
IgG-dependent generation of platelet-activating factor by normal and low density human eosinophils.
Topics: Calcimycin; Cells, Cultured; Eosinophils; Humans; Immunoglobulin G; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Aggregation; SRS-A | 1990 |
Effects of the protein kinase inhibitors, staurosporine and K-252a, on PGI2 production by rat liver cells (the C-9 cell line).
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Calcimycin; Carbazoles; Cell Line; Drug Synergism; Epoprostenol; Indole Alkaloids; Liver; Platelet Activating Factor; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Pharmacologic regulation of mediator generation and release from the murine bone marrow derived mast cell.
Topics: Animals; Basophils; Bone Marrow Cells; Calcimycin; Cell Division; Cells, Cultured; Histamine Release; Hydroxyeicosatetraenoic Acids; Immunoglobulin E; Lipoxygenase Inhibitors; Mast Cells; Mice; Platelet Activating Factor; Prostaglandin D2; Prostaglandins D | 1985 |
Mechanism of calcium ionophore A23187-induced priming of bone marrow-derived macrophages for tumor cell killing: relationship to priming by interferon.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Dose-Response Relationship, Drug; Interferons; Lipopolysaccharides; Macrophages; Male; Mice; Neoplasms, Experimental; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1985 |
Effects of CV-3988, an antagonist of platelet-activating factor (PAF), on washed rabbit platelets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Epoprostenol; Female; Osmolar Concentration; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thiazoles | 1986 |
The effect of vasoactive intestinal peptide and calcitonin gene-related peptide on peptidoleukotriene release from platelet activating factor stimulated rat lungs and ionophore stimulated guinea pig lungs.
Topics: Acetylcholine; Animals; beta-Endorphin; Calcimycin; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Endorphins; Guinea Pigs; In Vitro Techniques; Lung; Male; Neuropeptides; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Substance P; Vasoactive Intestinal Peptide | 1986 |
REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. I. Activity profile as an inhibitor of mediator release.
Topics: Animals; Antigens; Basophils; Calcimycin; Chromones; Cromolyn Sodium; Dextrans; Drug Synergism; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Mast Cells; Oxazoles; p-Methoxy-N-methylphenethylamine; Phosphatidylserines; Platelet Activating Factor; Rats; Tachyphylaxis; Time Factors | 1987 |
Effect of platelet activating factor on histamine release from rat mast cells.
Topics: Animals; Calcimycin; Histamine Release; In Vitro Techniques; Male; Mast Cells; Phospholipids; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1987 |
Whole blood white cell aggregation: a novel technique.
Topics: Adult; Calcimycin; Cell Aggregation; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor | 1987 |
Platelet-derived growth factor-induced c-myc RNA expression. Analysis of an inducible pathway independent of protein kinase C.
Topics: Calcimycin; Cycloheximide; Egtazic Acid; Ethers; Gene Expression Regulation; Humans; Ionomycin; Oncogenes; Osteosarcoma; Platelet Activating Factor; Protein Kinase C; RNA; Tumor Cells, Cultured | 1988 |
High molecular weight dextran sulfate inhibits intracellular Ca2+ release and decreases growth factor-induced increases in intracellular free Ca2+ in Swiss 3T3 fibroblasts.
Topics: Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dextran Sulfate; Dextrans; Fibroblasts; Guanosine Triphosphate; Halothane; Heparin; Inositol 1,4,5-Trisphosphate; Mitogens; Molecular Weight; Platelet Activating Factor; Receptors, Cell Surface | 1989 |
Relationship of GTP-binding proteins, phospholipase C, and PGE2 synthesis in rat glomerular mesangial cells.
Topics: Angiotensin II; Animals; Calcimycin; Dinoprostone; Glomerular Mesangium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol Phosphates; Platelet Activating Factor; Rats; Thionucleotides; Type C Phospholipases | 1989 |
Inhibitory effects of phenol derivatives on bovine platelet aggregation and their effects on Ca2+ mobilization.
Topics: 1-Octanol; Adenosine Diphosphate; Animals; Benzofurans; Blood Platelets; Calcimycin; Calcium; Cattle; Collagen; Cytoplasm; Fluorescent Dyes; Fura-2; Octanols; Phenols; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Solubility; Spectrometry, Fluorescence; Thrombin; Water | 1989 |
Biosynthesis of platelet-activating factor by cultured rat Kupffer cells stimulated with calcium ionophore A23187.
Topics: Acetyl Coenzyme A; Animals; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Liver; Platelet Activating Factor; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Reversal of A23187-induced airway constriction in the guinea pig.
Topics: Airway Obstruction; Airway Resistance; Albuterol; Animals; Calcimycin; Dose-Response Relationship, Drug; Ergolines; Guinea Pigs; Leukotrienes; Lung Compliance; Male; Platelet Activating Factor; Serotonin; Thromboxane A2 | 1989 |
Phorbol diester enhances calcium ionophore A23187-induced [3H]acetate incorporation into platelet-activating factor in murine macrophages: predominant incorporation into 1-O-acyl-2-acetyl-sn-glycero-3-phosphocholine.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Macrophages; Mice; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Evidence for an intracellular action of platelet-activating factor in bovine cultured aortic endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Thoracic; Azepines; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Platelet Activating Factor; Triazines; Triazoles | 1989 |
Inhibition studies on the membrane-associated phospholipase A2 in vitro and prostaglandin E2 production in vivo of the macrophage-like P388D1 cell. Effects of manoalide, 7,7-dimethyl-5,8-eicosadienoic acid, and p-bromophenacyl bromide.
Topics: Acetophenones; Calcimycin; Cell Line; Dinoprostone; Fatty Acids, Unsaturated; Kinetics; Macrophages; Melitten; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Substrate Specificity; Terpenes | 1989 |
The effects of TMB-8 on the shape changes of vascular endothelial cells resulting from exposure to various inflammatory agents.
Topics: Animals; Bradykinin; Calcimycin; Calcium Channel Blockers; Dinoprostone; Endothelium, Vascular; Gallic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inflammation; Leukotrienes; Platelet Activating Factor; Vena Cava, Inferior | 1989 |
Effects of human GM-CSF on neutrophil degranulation in vitro.
Topics: Calcimycin; Carrier Proteins; Colony-Stimulating Factors; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Secretory Rate; Transcobalamins; Vitamin B 12 | 1989 |
Prostaglandin production by cultured cynomolgus monkey trabecular meshwork cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Calcimycin; Cells, Cultured; Dexamethasone; Dinoprost; Dinoprostone; Humans; Macaca fascicularis; Platelet Activating Factor; Prostaglandins; Radioimmunoassay; Trabecular Meshwork | 1989 |
Quantitative analysis of platelet activating factor using fast atom bombardment/tandem mass spectrometry.
Topics: Calcimycin; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1989 |
Inhibition of platelet-activating factor biosynthesis via the acetyltransferase by arachidonic and oleic acids in ionophore A23187-stimulated bovine neutrophils.
Topics: Acetates; Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; In Vitro Techniques; Kinetics; Neutrophils; Oleic Acid; Oleic Acids; Platelet Activating Factor | 1989 |
Subcellular localization of phospholipids and enzymes involved in PAF-acether metabolism.
Topics: Acetyltransferases; Calcimycin; Cell Fractionation; Cell Membrane; Cytoplasmic Granules; Humans; Intracellular Membranes; Neutrophils; Phospholipids; Platelet Activating Factor; Tumor Cells, Cultured | 1989 |
Gamma-thrombin-induced phospholipase A2 activation in rabbit platelets: comparison with alpha-thrombin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Cytosol; Edetic Acid; Enzyme Activation; Humans; Kinetics; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rabbits; Structure-Activity Relationship; Thrombin | 1989 |
Synthesis of platelet-activating factor by human blood platelets and leucocytes. Evidence against selective utilization of cellular ether-linked phospholipids.
Topics: Acetates; Blood Platelets; Calcimycin; Ethers; Glycerylphosphorylcholine; Granulocytes; Humans; Kinetics; Leukocytes; Phenylmethylsulfonyl Fluoride; Phospholipids; Platelet Activating Factor; Thrombin | 1989 |
Augmented production of platelet-activating factor in human polymorphonuclear leukocytes by ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Calcimycin; Dimethyl Sulfoxide; Humans; Hydroxybutyrates; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Phospholipid remodeling in human neutrophils. Parallel activation of a deacylation/reacylation cycle and platelet-activating factor synthesis.
Topics: Acylation; Calcimycin; Fatty Acids, Nonesterified; Glycerol; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipids; Platelet Activating Factor | 1989 |
Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway.
Topics: Animals; Aspirin; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Heparin; Humans; In Vitro Techniques; Monocytes; Platelet Activating Factor; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human.
Topics: Animals; Bradykinin; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Dogs; Epithelium; Gas Chromatography-Mass Spectrometry; Humans; Isoproterenol; Kinetics; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Species Specificity; SRS-A; Thromboxane B2; Trachea | 1989 |
Modulation of arterial endothelial permeability: studies on an in vitro model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Albumins; Animals; Aorta, Thoracic; Arteries; Bradykinin; Calcimycin; Catalase; Endothelium, Vascular; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Permeability; Platelet Activating Factor; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate | 1989 |
Acetyltransferase activity and production of platelet-activating factor by human neutrophils activated with various stimuli.
Topics: Acetyltransferases; Calcimycin; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism of human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Aristolochic Acids; Calcimycin; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phenanthrenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1989 |
Involvement of guanine nucleotide binding proteins in neutrophil activation and priming by GM-CSF.
Topics: Calcimycin; Calcium; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; Leukotrienes; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Signal Transduction; Virulence Factors, Bordetella | 1989 |
Stimulation of platelet-activating factor synthesis by a nonmetabolizable bioactive analog of platelet-activating factor and influence of arachidonic acid metabolites.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetates; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phospholipases A; Platelet Activating Factor | 1989 |
The effect of adherence on the generation of reactive oxygen species by human neutrophilic granulocytes.
Topics: Calcimycin; Cell Adhesion; Complement C5; Complement C5a; Granulocytes; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Superoxides; Tumor Necrosis Factor-alpha | 1989 |
Inhibition of O2- generation by dexamethasone is mimicked by lipocortin I in alveolar macrophages.
Topics: Animals; Annexins; Calcimycin; Dexamethasone; Dinoprostone; Glycoproteins; Guinea Pigs; Humans; Macrophages; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pulmonary Alveoli; Recombinant Proteins; Superoxides | 1989 |
Equine peritoneal macrophage production of thromboxane and prostacyclin in response to platelet activating factor and its receptor antagonist SRI 63-441.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Endotoxins; Epoprostenol; Escherichia coli; Female; Horses; Macrophages; Male; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Quinolinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane A2; Thromboxane B2 | 1989 |
Inhibitory effects of nedocromil sodium on the in vitro induced migration and leukotriene formation of human granulocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Chemotaxis, Leukocyte; Cromolyn Sodium; Diterpenes; Eosinophils; Ginkgolides; Granulocytes; Humans; In Vitro Techniques; Lactones; Leukotriene B4; Leukotrienes; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; SRS-A; Zymosan | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Release of leukotriene B4 from rat Kupffer cells.
Topics: Animals; Benzoquinones; Calcimycin; Cells, Cultured; Kupffer Cells; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains; Zymosan | 1989 |
Effects of PAF and PAF antagonists on the shape of venous endothelial cells in vitro.
Topics: Animals; Calcimycin; Diterpenes; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Furans; Ginkgolides; Guinea Pigs; Lactones; Leukotriene E4; Lysophosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; SRS-A; Vena Cava, Inferior | 1989 |
Intracellular platelet-activating factor regulates eicosanoid generation in guinea-pig resident peritoneal macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Azepines; Calcimycin; Chromatography, High Pressure Liquid; Culture Media; Dinoprostone; Eicosanoids; Guinea Pigs; In Vitro Techniques; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Superoxides; Triazines; Triazoles | 1989 |
Release of platelet-activating factor and the metabolism of leukotriene B4 by the human neutrophil when studied in a cell superfusion model.
Topics: Acetates; Calcimycin; Cell-Free System; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Leukotriene B4; Models, Biological; Neutrophils; Perfusion; Platelet Activating Factor; Suspensions; Tritium | 1989 |
Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Macromolecular Substances; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Polymers; Prostaglandins; Prostaglandins B; Serum Albumin, Bovine; Structure-Activity Relationship; Umbilical Veins | 1989 |
CV 6209 is a non-competitive antagonist of platelet-activating factor receptors on guinea-pig resident peritoneal macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Epoprostenol; Guinea Pigs; In Vitro Techniques; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Pyridinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1989 |
[Effects of tetrandrine on cytoplasmic free calcium in rat neutrophils].
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcimycin; Calcium; Calcium Channel Blockers; Leukotriene B4; Neutrophils; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1989 |
Influence of immunologic activation and cellular fatty acid levels on the catabolism of platelet-activating factor within the murine mast cell (PT-18).
Topics: Animals; Antigens; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Fatty Acids; Glycerophosphates; Immunization; Mast Cells; Mice; Palmitoyl-CoA Hydrolase; Platelet Activating Factor | 1989 |
Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage.
Topics: Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Leukotriene B4; Macrophages; Masoprocol; Methionine; Neutrophils; Platelet Activating Factor; Pulmonary Alveoli; Zymosan | 1987 |
Comparison of the effects of indomethacin, RHC80267 and R59022 on superoxide production by 1,oleoyl-2,acetyl glycerol and A23187 in human neutrophils.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcimycin; Cyclohexanes; Cyclohexanones; Diglycerides; Glycerides; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Platelet Activating Factor; Pyrimidinones; Superoxides; Thiazoles | 1987 |
Effect of vasoactive intestinal peptide and calcitonin gene-related peptide on leukotriene release from guinea pig and rat lung.
Topics: Animals; Calcimycin; Calcitonin Gene-Related Peptide; Guinea Pigs; In Vitro Techniques; Leukotriene E4; Lung; Neuropeptides; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Vasoactive Intestinal Peptide | 1987 |
Potential involvement of vicinal sulfhydryls in stimulus-induced rabbit platelet activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arsenicals; Blood Platelets; Calcimycin; Cyclic AMP; Molecular Weight; Platelet Activating Factor; Rabbits; Sulfhydryl Reagents; Thrombin | 1987 |
Effects of baicalein on leukotriene biosynthesis and degranulation in human polymorphonuclear leukocytes.
Topics: Calcimycin; Calcium; Cyclic AMP; Cytochalasin B; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glucuronidase; Humans; Muramidase; Neutrophils; Platelet Activating Factor; SRS-A | 1987 |
The effects of N-3 polyunsaturated fatty acids on the generation of platelet-activating factor-acether by human monocytes.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fish Oils; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Platelet Activating Factor | 1987 |
Biosynthesis of platelet-activating factor in human polymorphonuclear leukocytes. Involvement of the cholinephosphotransferase pathway in response to the phorbol esters.
Topics: Acetyltransferases; Calcimycin; Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Dithiothreitol; Dose-Response Relationship, Drug; Glyceryl Ethers; Humans; Neutrophils; Phorbol Esters; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages.
Topics: Calcimycin; Cells, Cultured; Diglycerides; Hydrolysis; Inositol Phosphates; Macrophages; Oxygen; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Modulation of leucocyte activation in the early phase of the rabbit burn injury.
Topics: Animals; Burns; Calcimycin; Disease Models, Animal; Diterpenes; Free Radicals; Ginkgolides; Lactones; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides | 1988 |
Release of leukotrienes from porcine and human blood vessels by immunological and nonimmunological stimuli.
Topics: Animals; Antibodies, Anti-Idiotypic; Blood Vessels; Calcimycin; Cerebral Arteries; Coronary Circulation; Coronary Vessels; Female; Humans; Immunoglobulin E; Immunoglobulin G; Indomethacin; Leukotriene B4; Leukotriene E4; Platelet Activating Factor; Pulmonary Artery; SRS-A; Swine | 1988 |
Platelet activating factor and leukotriene B4 induce hyperpolarization of human endothelial cells but depolarization of neutrophils.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Separation; Concanavalin A; Cytoplasm; Digitonin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Protons; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Kinetics of the formation of thrombin-thrombospondin complexes: involvement of a 77-kDa intermediate.
Topics: Binding, Competitive; Blood Platelets; Calcimycin; Calcium; Glycoproteins; Humans; Kinetics; Platelet Activating Factor; Protein Precursors; Receptors, Cell Surface; Receptors, Thrombin; Thrombin; Thrombospondins | 1988 |
Acetylcholine and dopamine promote the production of platelet activating factor in immature cells of chick embryonic retina.
Topics: Acetylcholine; Animals; Calcimycin; Chick Embryo; Choline O-Acetyltransferase; Diacylglycerol Cholinephosphotransferase; Dithiothreitol; Dopamine; Enzyme Activation; Kinetics; Platelet Activating Factor; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Dopamine D2; Retina | 1988 |
Inhibition of eicosanoid and PAF formation by dexamethasone in rat inflammatory polymorphonuclear neutrophils may implicate lipocortin 's'.
Topics: Annexins; Calcimycin; Dexamethasone; Dinoprostone; Glycoproteins; Humans; Inflammation; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1988 |
Leukotriene C4 production from human eosinophils in vitro. Role of eosinophil chemotactic factors on eosinophil activation.
Topics: Adult; Calcimycin; Cells, Cultured; Chemotactic Factors; Chemotactic Factors, Eosinophil; Enzyme Activation; Eosinophils; Female; Humans; Leukotriene B4; Male; Phosphatidylserines; Platelet Activating Factor; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1988 |
Characterization of receptors for platelet-activating factor on platelets, polymorphonuclear leukocytes and macrophages.
Topics: Animals; Azepines; Blood Platelets; Calcimycin; Cell Aggregation; Diterpenes; Epoprostenol; Furans; Ginkgolides; In Vitro Techniques; Lactones; Macrophages; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazines; Triazoles | 1988 |
Activation of washed chicken thrombocytes by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (platelet-activating factor).
Topics: Animals; Blood Platelets; Calcimycin; Calcium; Cations, Divalent; Chickens; Collagen; Egtazic Acid; Kinetics; Magnesium; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1985 |
Chick retina generates platelet-activating factor.
Topics: Animals; Calcimycin; Chickens; In Vitro Techniques; Neurotransmitter Agents; Phosphatidylinositols; Platelet Activating Factor; Retina | 1987 |
Inhibitory effect of platelet-activating factor (PAF) on luteinizing hormone-releasing hormone and somatostatin release from rat median eminence in vitro correlated with the characterization of specific PAF receptor sites in rat hypothalamus.
Topics: Animals; Calcimycin; Cell Membrane; Gonadotropin-Releasing Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Hypothalamo-Hypophyseal System; Hypothalamus; Kinetics; Luteinizing Hormone; Male; Median Eminence; Pituitary Gland, Anterior; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Somatostatin | 1988 |
Role of platelet-activating factor in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine and prednisolone.
Topics: Adult; Aminosalicylic Acids; Calcimycin; Colitis, Ulcerative; Colon; Drug Combinations; Female; Glucosamine; Humans; Immunoglobulin E; Intestinal Mucosa; Male; Middle Aged; Platelet Activating Factor; Prednisolone; Rectum; Sulfapyridine; Sulfasalazine | 1988 |
Synergistic effects of platelet-activating factor and other platelet agonists in human platelet aggregation and release: the role of ADP and products of the cyclooxygenase pathway.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Calcimycin; Collagen; Drug Synergism; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thrombin | 1985 |
Decrease in IgE Fc receptor expression on mouse bone marrow-derived mast cells and inhibition of paf-acether formation and of beta-hexosaminidase release by dexamethasone.
Topics: Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcimycin; Dexamethasone; Enzyme Activation; Hexosaminidases; Immunoglobulin E; Immunosuppressive Agents; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Platelet Activating Factor; Receptors, Fc; Receptors, IgE | 1986 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Inhibition of phospholipase A2 activity of guinea-pig alveolar macrophages by lipocortin-like proteins purified from mice lung.
Topics: Animals; Annexins; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Glycoproteins; Guinea Pigs; Lung; Macrophages; Mice; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pulmonary Alveoli | 1988 |
Neutrophil degranulation: evidence pertaining to its mediation by the combined effects of leukotriene B4, platelet-activating factor, and 5-HETE.
Topics: Animals; Calcimycin; Complement C5; Complement C5a; Cytoplasmic Granules; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits | 1985 |
Cyclic AMP inhibits platelet activation independently of its effect on cytosolic free calcium.
Topics: Adenosine Diphosphate; Aminoquinolines; Blood Platelets; Bucladesine; Calcimycin; Calcium; Cyclic AMP; Cytosol; Epoprostenol; Humans; Platelet Activating Factor; Thrombin | 1985 |
Mechanisms of endothelium-dependent vascular smooth muscle relaxation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cyclic GMP; Cyclooxygenase Inhibitors; Endothelium; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Activating Factor; Receptors, Muscarinic; Vasoconstriction; Vasodilation; Vasodilator Agents | 1985 |
Exclusive leukotriene C4 synthesis by purified human eosinophils induced by opsonized zymosan.
Topics: Calcimycin; Eosinophils; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Platelet Activating Factor; SRS-A; Zymosan | 1985 |
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.
Topics: Arthritis, Rheumatoid; Bacterial Infections; C-Reactive Protein; Calcimycin; Cytochalasin B; Free Radicals; Humans; Hydrogen Peroxide; Leukocyte Count; Neutrophils; Oxygen; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Platelet-activating factor and leukotriene biosynthesis is inhibited in polymorphonuclear leukocytes depleted of arachidonic acid.
Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dietary Fats; Leukotriene B4; Neutrophils; Oligopeptides; Platelet Activating Factor; Rats | 1986 |
Leukotriene B4 biosynthesis in polymorphonuclear leukocytes from blood of umbilical cord, infants, children, and adults.
Topics: Adolescent; Adult; Aging; Calcimycin; Child; Child, Preschool; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Leukotriene B4; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Production of platelet-activating factor by chick retina.
Topics: Acetylcholine; Amino Acids; Animals; Calcimycin; Chickens; Diacylglycerol Cholinephosphotransferase; Dopamine; Epinephrine; Histamine; In Vitro Techniques; Kinetics; Platelet Activating Factor; Retina | 1986 |
Stimulated release of neutral proteinases elastase and cathepsin G from inflammatory rat polymorphonuclear leukocytes.
Topics: Animals; Calcimycin; Cathepsin G; Cathepsins; Cytoplasmic Granules; Dose-Response Relationship, Drug; Inflammation; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peritoneal Cavity; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serine Endopeptidases | 1987 |
Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism.
Topics: Calcimycin; Cell Adhesion; Cell Aggregation; Humans; Leukotriene B4; Neutrophils; Platelet Activating Factor; Solubility | 1987 |
Signalling for increased cytoskeletal actin in neutrophils.
Topics: Actins; Animals; Calcimycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Pertussis Toxin; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Calcimycin; Collagen; Diglycerides; Epinephrine; Female; Humans; Lupus Erythematosus, Systemic; Phorbols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 1986 |
Metabolism of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human promyelocytic leukemic HL60 cells. Stimulated expression of phospholipase A2 and acetyltransferase requires differentiation.
Topics: Acetyltransferases; Calcimycin; Calcium; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1986 |
Production of platelet-activating factor in glomeruli and cultured glomerular mesangial cells.
Topics: Animals; Biological Assay; Calcimycin; Cells, Cultured; Glomerular Mesangium; Kidney Glomerulus; Male; Mass Spectrometry; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tritium | 1986 |
Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet-activating factor is mediated by leukotriene C4.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Calcimycin; Coronary Vessels; Heart; In Vitro Techniques; Lipoxygenase; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A; Time Factors; Vasoconstriction | 1986 |
The intracellular retention of newly synthesized platelet-activating factor.
Topics: Adult; Animals; Basophils; Calcimycin; Cattle; Cell Separation; Cells, Cultured; Endothelium; Female; Humans; Kinetics; Male; Neutrophils; Platelet Activating Factor; Pulmonary Artery; Rabbits | 1986 |
Acetyltransferase activity in human platelet microsomes and washed platelets.
Topics: Acetates; Acetyltransferases; Adult; Blood Platelets; Calcimycin; Enzyme Activation; Humans; Microsomes; Platelet Activating Factor; Thrombin | 1986 |
Synthesis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) in exocrine glands and its control by secretagogues.
Topics: Acetates; Acetic Acid; Animals; Calcimycin; Carbachol; Ceruletide; Cholecystokinin; Exocrine Glands; Exocytosis; Extracellular Space; Guinea Pigs; Male; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Tissue Distribution | 1986 |
Metabolism of 5-hydroxyicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative.
Topics: Calcimycin; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; Neutrophils; Oxidation-Reduction; Phospholipids; Platelet Activating Factor; Spectrum Analysis; Triglycerides | 1986 |
Different concentrations of pertussis toxin have opposite effects on agonist-induced PGE2 formation in mesangial cells.
Topics: Angiotensin II; Animals; Calcimycin; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; GTP-Binding Proteins; In Vitro Techniques; Kidney Glomerulus; Membrane Proteins; Molecular Weight; NAD; Pertussis Toxin; Platelet Activating Factor; Prostaglandins E; Rats; Virulence Factors, Bordetella | 1986 |
Ionophore-stimulated rat basophilic leukemia cells produce PAF-acether.
Topics: Animals; Basophils; Calcimycin; Guinea Pigs; Leukemia, Experimental; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats | 1987 |
Species-specific variations in the molecular heterogeneity of the platelet-activating factor.
Topics: Animals; Calcimycin; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Mice; Platelet Activating Factor; Rats; Species Specificity; Structure-Activity Relationship | 1987 |
Some unique features of the metabolic conversion of platelet-activating factor (AGEPC) to alkyl acyl PC by washed rabbit platelets.
Topics: Animals; Blood Platelets; Calcimycin; Calcium; Collagen; Platelet Activating Factor; Rabbits; Thrombin | 1987 |
Effects of the lipid peroxidation product 4-hydroxynonenal on the aggregation of human platelets.
Topics: Adenosine Diphosphate; Aldehydes; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Drug Antagonism; Fatty Acids; Glutathione; Humans; In Vitro Techniques; Malondialdehyde; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1987 |
Quantitation of lyso-platelet activating factor molecular species from human neutrophils by mass spectrometry.
Topics: Calcimycin; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Lysophosphatidylcholines; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1987 |
Antigen-and ionophore-stimulated synthesis of platelet-activating factor by the cloned mast cell line, MC9.
Topics: Acetates; Acetic Acid; Animals; Calcimycin; Cell Line; Haptens; Immunoglobulin E; Mast Cells; Platelet Activating Factor; Platelet Aggregation; Rabbits; Receptors, Fc; Tritium | 1987 |
The role of Ca2+ in regulating the catabolism of PAF-acether (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in rabbit platelets.
Topics: Acetates; Acetic Acid; Animals; Blood Platelets; Calcimycin; Calcium; In Vitro Techniques; Platelet Activating Factor; Rabbits; Thrombin | 1987 |
Antiplatelet effect of butylidenephthalide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Calcimycin; Collagen; Dinoprostone; Guinea Pigs; Humans; In Vitro Techniques; Phthalic Acids; Phthalic Anhydrides; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Thromboxane B2 | 1987 |
Biosynthesis and metabolism of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine in rat glomerular mesangial cells.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Glomerular Mesangium; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1987 |
1-Acyl-2-acetyl-sn-glycero-3-phosphocholine from stimulated human polymorphonuclear leukocytes.
Topics: Animals; Blood Platelets; Calcimycin; Chromatography, Thin Layer; Humans; Kinetics; Mass Spectrometry; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1987 |
Human neutrophil platelet-activating factor: molecular heterogeneity in unstimulated and ionophore-stimulated cells.
Topics: Acetates; Acetic Acid; Calcimycin; Gas Chromatography-Mass Spectrometry; Humans; Neutrophils; Platelet Activating Factor | 1987 |
Porcine coronary arteries with regenerated endothelium have a reduced endothelium-dependent responsiveness to aggregating platelets and serotonin.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Coronary Circulation; Coronary Vessels; Endothelium; In Vitro Techniques; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Platelet Activating Factor; Platelet Aggregation; Regeneration; Serotonin; Swine; Thrombin; Vasopressins | 1987 |
Platelet-activating factor induces leukotriene C4 synthesis by purified human eosinophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Drug Synergism; Eosinophils; Humans; Platelet Activating Factor; Radioimmunoassay; SRS-A; Time Factors; Zymosan | 1987 |
Platelet-activating factor both stimulates and "primes" human polymorphonuclear leukocyte actin filament assembly.
Topics: Actin Cytoskeleton; Actins; Calcimycin; Calcium; Cytoskeleton; Drug Synergism; Egtazic Acid; Humans; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Quinolinium Compounds; Time Factors; Virulence Factors, Bordetella | 1987 |
Effect of platelet activating factor antagonists on cultured rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Cells, Cultured; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Glomerular Mesangium; Lactones; Lignans; Male; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Rats; Thiazoles | 1987 |
Platelet-activating factor (PAF-acether) formation in rat basophilic leukemia cells stimulated by ionophore A23187.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Basophils; Calcimycin; Leukemia, Experimental; Platelet Activating Factor; Quinacrine; Rats | 1987 |
Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes.
Topics: Calcimycin; Cell Adhesion; Cell Differentiation; Humans; Macrophage Activation; Monocytes; Opsonin Proteins; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Adherence of human basophils to cultured umbilical vein endothelial cells.
Topics: Basophils; Calcimycin; Cations, Divalent; Cell Adhesion; Cell Line; Complement C5; Complement C5a; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1988 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Human platelet electrorotation change induced by activation: inducer specificity and correlation to serotonin release.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Cell Membrane; Collagen; Cytoplasmic Granules; Electric Conductivity; Electrophysiology; Epinephrine; Humans; Kinetics; Microscopy, Electron; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin | 1988 |
Molecular species of platelet-activating factor generated by human neutrophils challenged with ionophore A23187.
Topics: Adult; Animals; Calcimycin; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Male; Neutrophils; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits | 1985 |
Vasoconstrictor-evoked prostaglandin synthesis in cultured human mesangial cells.
Topics: Angiotensin II; Arginine Vasopressin; Butyrates; Butyric Acid; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Platelet Activating Factor; Prostaglandins; Surface Properties; Time Factors; Vasoconstrictor Agents | 1985 |
Lipoxygenase products of arachidonic acid modulate biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) by human neutrophils via phospholipase A2.
Topics: Acetates; Acetic Acid; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Masoprocol; Membrane Lipids; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Trifluoperazine | 1985 |
Action mechanism of the platelet aggregation inducer and inhibitor from Echis carinatus snake venom.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chymotrypsin; Collagen; Fibrinogen; Heparin; Hirudins; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Thrombin; Viper Venoms | 1985 |
The 5-lipoxygenase products can modulate the synthesis of platelet-activating factor (alkyl-acetyl GPC) in Ca-ionophore A23187-stimulated rat peritoneal macrophages.
Topics: Acetophenones; Animals; Arachidonic Acids; Benzoquinones; Calcimycin; Carbon Radioisotopes; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotrienes; Lipid Peroxides; Macrophages; Male; Platelet Activating Factor; Quinones; Rats; Rats, Inbred Strains | 1985 |
Subcellular localization of vasopressin-like material in platelets.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; Microscopy, Electron; Norepinephrine; Platelet Activating Factor; Subcellular Fractions | 1985 |
Evidence that biosynthesis of platelet-activating factor (paf-acether) by human neutrophils occurs in an intracellular membrane.
Topics: Acetyltransferases; Calcimycin; Cell Fractionation; Endoplasmic Reticulum; Humans; Intracellular Membranes; Neutrophils; Platelet Activating Factor | 1985 |
Production of platelet-activating factor by washed rabbit platelets.
Topics: Animals; Blood Platelets; Calcimycin; Leukocyte Count; Male; Phospholipids; Platelet Activating Factor; Rabbits | 1985 |
Platelet-activating factor metabolism in human amnion and the responses of this tissue to extracellular platelet-activating factor.
Topics: Amnion; Calcimycin; Calcium; Dinoprostone; Egtazic Acid; Female; Humans; Labor, Obstetric; Platelet Activating Factor; Pregnancy; Prostaglandins E | 1985 |
Biological activity of platelet activating factor-amidophosphonate (PAF-AP), a novel phosphonolipid selective inhibitor of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Diglycerides; Epinephrine; Humans; Oxidation-Reduction; Phosphatidic Acids; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1985 |
Potentiation of leukotriene formation in pulmonary and vascular tissue.
Topics: Animals; Blood Vessels; Calcimycin; Cats; Guinea Pigs; In Vitro Techniques; Leukotriene E4; Lung; Meclofenamic Acid; Platelet Activating Factor; Rats; SRS-A; Time Factors | 1984 |
Regulation of human platelet activation--analysis of cyclooxygenase and cyclic AMP-dependent pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Serotonin; Thrombin; Thromboxane B2 | 1984 |
Release of platelet-activating factor, slow-reacting substance, and vasoactive amines from isolated rat kidneys.
Topics: Animals; Autacoids; Calcimycin; Histamine Release; Immunization; Kidney; Male; p-Methoxy-N-methylphenethylamine; Perfusion; Platelet Activating Factor; Rats; Rats, Inbred BN; Rats, Inbred Strains; Serotonin; SRS-A | 1984 |
The role of calcium ions in the process of acetyltransferase activation during the formation of platelet-activating factor (PAF-acether).
Topics: Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Animals; Biological Transport; Calcimycin; Calcium; Enzyme Activation; Gallic Acid; In Vitro Techniques; Macrophages; Platelet Activating Factor; Rats; Rats, Inbred Strains; Zymosan | 1984 |
Platelet-activating factor-induced aggregation of human platelets specifically inhibited by triazolobenzodiazepines.
Topics: Adenosine Diphosphate; Alprazolam; Anti-Anxiety Agents; Arachidonic Acid; Arachidonic Acids; Benzodiazepines; Blood Platelets; Calcimycin; Chromatography, Gel; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation; Thrombin; Triazolam | 1984 |
Release of platelet-activating factor (PAF) and histamine. II. The cellular origin of human PAF: monocytes, polymorphonuclear neutrophils and basophils.
Topics: Antigen-Antibody Complex; Basophils; Blood Coagulation Factors; Blood Platelets; Calcimycin; Cytoplasmic Granules; Histamine Release; Humans; In Vitro Techniques; Leukocytes; Lysophosphatidylcholines; Microscopy, Electron; Monocytes; Neutrophils; Phagocytosis; Platelet Activating Factor; Platelet Aggregation | 1981 |
Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Humans; In Vitro Techniques; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Evidence for 5, 12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation.
Topics: Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Kinetics; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1981 |
Antigen-initiated release of platelet-activating factor (PAF-acether) from mouse bone marrow-derived mast cells sensitized with monoclonal IgE.
Topics: Animals; Antigens; Bone Marrow Cells; Calcimycin; Hexosaminidases; Immunoglobulin E; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Platelet Activating Factor; SRS-A | 1983 |
Differential activation of phosphatidylinositol deacylation and a pathway via diphosphoinositide in macrophages responding to zymosan and ionophore A23187.
Topics: Animals; Calcimycin; Calcium; Kinetics; Macrophages; Mice; Monensin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Platelet Activating Factor; Zymosan | 1984 |
Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine by rat alveolar macrophages. Phospholipase A2 and acetyltransferase activities during phagocytosis and ionophore stim
Topics: Acetyltransferases; Animals; Anti-Bacterial Agents; Calcimycin; Kinetics; Lung; Macrophages; Phagocytosis; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Rats; Zymosan | 1983 |
5-L-hydroxy-6,8,11,14-eicosatetraenoate potentiates the human neutrophil degranulating action of platelet-activating factor.
Topics: Arachidonic Acids; Calcimycin; Complement C5; Complement C5a; Drug Synergism; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Time Factors | 1983 |
CV-3988 - a specific antagonist of platelet activating factor (PAF).
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcimycin; Collagen; Dose-Response Relationship, Drug; Male; Micelles; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1983 |
Biosynthesis of platelet-activating factor (PAF-acether). V. Enhancement of acetyltransferase activity in murine peritoneal cells by calcium ionophore A23187.
Topics: Acetyltransferases; Animals; Anti-Bacterial Agents; Ascitic Fluid; Calcimycin; Enzyme Activation; In Vitro Techniques; Lysophosphatidylcholines; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1983 |
Biosynthesis of platelet activating factor in rabbit polymorphonuclear neutrophils.
Topics: Acetates; Acylation; Animals; Ascitic Fluid; Calcimycin; Calcium; Fatty Alcohols; Kinetics; Neutrophils; Platelet Activating Factor; Rabbits | 1983 |
Human and rabbit platelets form platelet-activating factor in response to calcium ionophore.
Topics: Animals; Anti-Bacterial Agents; Blood Platelets; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Humans; Platelet Activating Factor; Rabbits; Stimulation, Chemical | 1983 |
1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine: a novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Neutrophils; Platelet Activating Factor; Rabbits; Stearic Acids | 1983 |
Studies on the stimulation of human blood platelets by semi-synthetic platelet-activating factor.
Topics: Adenosine Diphosphate; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Serotonin; Time Factors | 1983 |
Defective platelet aggregation to the calcium ionophore A23187 in a patient with a lifelong bleeding disorder.
Topics: Arachidonic Acids; Bleeding Time; Blood Platelet Disorders; Calcimycin; Calcium; Female; Humans; Middle Aged; Nucleotides; Platelet Activating Factor; Platelet Aggregation; Thromboxane A2 | 1983 |
The release of platelet-activating factor from human endothelial cells in culture.
Topics: Angiotensin II; Animals; Calcimycin; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Endothelium; Factor VIII; Humans; Platelet Activating Factor; Rabbits; Umbilical Veins; Vasopressins | 1983 |
Calmodulin antagonists inhibit formation of platelet-activating factor in stimulated human neutrophils.
Topics: Calcimycin; Calcium; Calmodulin; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Sulfonamides; Trifluoperazine | 1984 |
Application of selected ion monitoring to determination of platelet-activating factor.
Topics: Adult; Calcimycin; Humans; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1983 |
Increased biosynthesis of platelet-activating factor in activated human eosinophils.
Topics: Acetyltransferases; Calcimycin; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Eosinophils; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Platelet Activating Factor | 1984 |
Effect of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine on calcium fluxes by human platelet microsomes.
Topics: Arachidonic Acid; Arachidonic Acids; Biological Transport; Blood Platelets; Calcimycin; Calcium; Dose-Response Relationship, Drug; Humans; Microsomes; Phosphatidic Acids; Platelet Activating Factor | 1984 |
Effects of tris on responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Tromethamine | 1984 |
Structure elucidation of platelet activating factor derived from human neutrophils.
Topics: Adult; Calcimycin; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Neutrophils; Platelet Activating Factor; Zymosan | 1984 |
Diacylglycerols enhance human neutrophil degranulation responses: relevancy to a multiple mediator hypothesis of cell function.
Topics: Animals; Calcimycin; Cytoplasmic Granules; Diglycerides; Glycerides; Humans; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine. A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Humans; Models, Biological; Neutrophils; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Time Factors; Zymosan | 1984 |
Release of arachidonic acid from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine, a precursor of platelet-activating factor, in rat alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Fatty Acids; Kinetics; Macrophages; Platelet Activating Factor; Rats; Structure-Activity Relationship; Tritium | 1984 |
The influence of PAF on the metabolization of arachidonic acid by human blood platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Humans; Kinetics; Malondialdehyde; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1984 |
[Release of platelet activating factor (P.A.F.-acether) by isolated perfused rat kidney].
Topics: Animals; Calcimycin; Hypersensitivity, Immediate; Kidney; Kinetics; Leukocytes; Lysophosphatidylcholines; Male; Perfusion; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats | 1980 |
Platelet-activating factor (PAF-acether) secretion from platelets: effect of aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Coagulation Factors; Blood Platelets; Calcimycin; Collagen; In Vitro Techniques; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Time Factors | 1980 |
Release of platelet-activating factor (PAF-acether) from alveolar macrophages by the calcium ionophore A23187 and phagocytosis.
Topics: Animals; Anti-Bacterial Agents; Blood Platelets; Calcimycin; Calcium; Humans; Lysophosphatidylcholines; Macrophages; Phagocytosis; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Rabbits; Rats | 1980 |
Requirements for different Ca2+ pools in the activation of rabbit platelets. I. release reaction and protein phosphorylation.
Topics: Animals; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Gallic Acid; Lysophosphatidylcholines; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Time Factors | 1982 |
Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Coagulation Factors; Calcimycin; Cattle; Cytochalasin B; Glucuronidase; Kinetics; Lipoxygenase; Lysophosphatidylcholines; Muramidase; Myocardium; Neutrophils; Platelet Activating Factor; Rabbits | 1982 |
Biosynthesis of platelet-activating factor (PAF-ACETHER). II. Involvement of phospholipase A2 in the formation of PAF-ACETHER and lyso-PAF-ACETHER from rabbit platelets.
Topics: Acetophenones; Animals; Blood Platelets; Calcimycin; Edetic Acid; Egtazic Acid; Kinetics; Lysophosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rabbits; Thrombin | 1982 |
Release of platelet-activating factor (PAF-acether) and arachidonic acid metabolites from alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Humans; In Vitro Techniques; Inflammation; Lysophosphatidylcholines; Macrophages; Papio; Platelet Activating Factor; Pulmonary Alveoli; Rats | 1981 |
Biosynthesis of platelet-activating factor (PAF-acether). IV. Impairment of acetyl-transferase activity in thioglycollate-elicited mouse macrophages.
Topics: Acetyl Coenzyme A; Acetyltransferases; Animals; Calcimycin; Female; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Thioglycolates; Zymosan | 1982 |
Activities of enzymes that metabolize platelet-activating factor (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine) in neutrophils and eosinophils from humans and the effect of a calcium ionophore.
Topics: Acetyltransferases; Alkyl and Aryl Transferases; Anti-Bacterial Agents; Calcimycin; Carboxylic Ester Hydrolases; Eosinophils; Humans; Kinetics; Lysophosphatidylcholines; Neutrophils; Platelet Activating Factor; Transferases | 1982 |
Effect of platelet activating factor on leukocytes. II. Enhancement of eosinophil chemotactic factor and beta-glucuronidase release.
Topics: Calcimycin; Chemotactic Factors; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement System Proteins; Drug Synergism; Eosinophils; Glucuronidase; Humans; Inflammation; Neutrophils; Platelet Activating Factor; Zymosan | 1982 |
Inhibition of leukotriene C4 and B4 release by human eosinophils with the new 5-lipoxygenase inhibitor 6-hydroxy-2(4-sulfamoylbenzylamino)-4,5,7-trimethylbenzothiazo le hydrochloride.
Topics: Asthma; Calcimycin; Dose-Response Relationship, Drug; Eosinophils; Humans; In Vitro Techniques; Ionophores; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Platelet Activating Factor; Thiazoles | 1995 |
Zymosan-induced IL-8 release from human neutrophils involves activation via the CD11b/CD18 receptor and endogenous platelet-activating factor as an autocrine modulator.
Topics: Antibodies, Monoclonal; Calcimycin; CD18 Antigens; Humans; Integrins; Interleukin 1 Receptor Antagonist Protein; Interleukin-8; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sialoglycoproteins; Tetrazoles; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
The pathophysiological roles of heterogeneous eosinophils in allergic rhinitis caused by house dust mites.
Topics: Allergens; Animals; Calcimycin; Cell Separation; Dust; Eosinophils; Humans; Inflammation Mediators; Ionophores; Leukotriene C4; Mites; Platelet Activating Factor; Rhinitis, Allergic, Perennial; Specific Gravity; Superoxides | 1995 |
Effects of tetrandrine on rabbit platelet aggregation and platelet activating factor generation.
Topics: Alkaloids; Animals; Benzylisoquinolines; Blood Platelets; Calcimycin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits | 1995 |
High precision measurement of electrical resistance across endothelial cell monolayers.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Electric Impedance; Endothelium, Vascular; Histamine; Humans; Leukotriene C4; Platelet Activating Factor; Thrombin; Umbilical Veins | 1995 |
Inhaled A23187 produces a preferential sensitization to substance P.
Topics: Animals; Bronchial Provocation Tests; Bronchoconstriction; Calcimycin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Lung Volume Measurements; Male; Neprilysin; Platelet Activating Factor; SRS-A; Substance P; Thiorphan | 1993 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
Differential regulation of leukotriene and platelet-activating factor synthesis in rat alveolar macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Leukotrienes; Macrophages, Alveolar; Male; Phospholipases; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Zymosan | 1995 |
Comparison of neutrophil chemotactic factor release by human and rabbit alveolar macrophages in response to tannin exposure.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Chemotaxis, Leukocyte; Culture Media, Conditioned; Humans; Hydrolyzable Tannins; Interleukin-8; Lipoxygenase Inhibitors; Macrophages, Alveolar; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1995 |
In vitro and in vivo impact of a new glycosphingolipid on neutrophils.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Calcimycin; Cell Adhesion; Chemotaxis, Leukocyte; Eicosanoids; Erythrocytes; Gangliosides; Hemolysis; Humans; In Vitro Techniques; Inflammation; Leukocyte Count; Mice; Neutrophils; Phagocytosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Superoxides | 1994 |
IL-1 beta and IL-6 stimulate the production of platelet-activating factor (PAF) by cultured rabbit synovial cells.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Interleukin-1; Interleukin-6; Platelet Activating Factor; Rabbits; Synovial Membrane | 1995 |
Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes.
Topics: Asthma; Calcimycin; Dibenzazepines; Histamine H1 Antagonists; Humans; Hypersensitivity; Imidazoles; Immunoglobulin E; In Vitro Techniques; Ketotifen; Leukocytes; Leukotriene C4; Neutrophils; Piperazines; Platelet Activating Factor | 1995 |
Effect of anti-neutrophil cytoplasm autoantibodies on the intracellular calcium concentration of human neutrophils.
Topics: Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Calcimycin; Calcium; Cells, Cultured; Granulomatosis with Polyangiitis; Humans; Immunoglobulin G; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Polyarteritis Nodosa | 1994 |
Effects of antipsoriatic drugs on biosynthesis of platelet activating factor by human keratinocytes.
Topics: Calcimycin; Cells, Cultured; Dexamethasone; Humans; Keratinocytes; Mechlorethamine; Platelet Activating Factor; Skin | 1994 |
Lectin-induced increase in microvascular permeability to colloidal carbon in vitro may involve protein kinase C activation.
Topics: Animals; Calcimycin; Capillary Permeability; Carbon; Concanavalin A; Enzyme Activation; In Vitro Techniques; Indoles; Intestine, Small; Lectins; Peanut Agglutinin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Rats; Serotonin; Wheat Germ Agglutinins | 1994 |
Production and metabolism of platelet-activating factor in the normal and ischemic fetal rat brain.
Topics: Animals; Biological Assay; Blood Platelets; Brain; Calcimycin; Choline; Half-Life; Ischemic Attack, Transient; Kinetics; Phosphatidylinositol Phosphates; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Tritium; Type C Phospholipases | 1994 |
Activation of a potassium outward current by zymosan and opsonized zymosan in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Cell Membrane; In Vitro Techniques; Macrophages; Male; Membrane Potentials; Mice; Opsonin Proteins; Patch-Clamp Techniques; Platelet Activating Factor; Potassium Channels; Receptors, Fc; Zymosan | 1994 |
Dissociation between secretion and protein phosphorylation in agonist-stimulated platelets; action of PCA-4230, a new antithrombotic drug.
Topics: Animals; Blood Platelets; Blood Proteins; Calcimycin; Cytoplasmic Granules; Dihydropyridines; Fibrinolytic Agents; Phosphorylation; Platelet Activating Factor; Rabbits; Thrombin | 1994 |
[Effects of calcimycin on platelet adhesion to cultured bovine cerebral microvascular endothelial cells and its antagonism by drugs].
Topics: Alkaloids; Animals; Azepines; Benzylisoquinolines; Brain; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Male; Microcirculation; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Pyrans; Rabbits; Triazoles | 1994 |
BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.
Topics: Arachidonic Acid; Benzoxazoles; Calcimycin; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1994 |
Effect of platelet-activating factor on motility and acrosome reaction of human spermatozoa.
Topics: Acrosome; Calcimycin; Calcium; Humans; Male; Platelet Activating Factor; Sperm Motility; Spermatozoa | 1994 |
Autocrine enhancement of leukotriene synthesis by endogenous leukotriene B4 and platelet-activating factor in human neutrophils.
Topics: Amino Acid Sequence; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Complement C5a; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotriene B4; Leukotrienes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Signal Transduction; Virulence Factors, Bordetella | 1994 |
Eicosanoid and inositol phosphate response to platelet-activating factor (PAF) and to a PAF antagonist in rat astroglial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Astrocytes; Calcimycin; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Eicosanoids; Ginkgolides; Inositol; Inositol Phosphates; Kinetics; Lactones; Platelet Activating Factor; Rats; Thromboxane B2 | 1994 |
A mechanism for phorbol ester-mediated regulation of the PAF receptor in human neutrophils.
Topics: Calcimycin; Calcium; Cytochalasin B; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Effect of terfenadine on human eosinophil and neutrophil chemotactic response and generation of superoxide.
Topics: Adult; Asthma; Calcimycin; Cell Degranulation; Cell Separation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rhinitis; Superoxides; Terfenadine | 1994 |
A novel syndrome of severe neutrophil dysfunction: unresponsiveness confined to chemotaxin-induced functions.
Topics: Actins; Antigens, CD; Calcimycin; Calcium; CD18 Antigens; CD4 Antigens; CD8 Antigens; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Cytochalasin B; Endothelium, Vascular; Female; Humans; Immunologic Deficiency Syndromes; In Vitro Techniques; Infant, Newborn; Kinetics; Leukocyte Count; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Reference Values; Sepsis; Syndrome; T-Lymphocyte Subsets | 1993 |
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxis.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Line; Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Cytokines; Egtazic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation.
Topics: Calcimycin; Calcium; Cell Aggregation; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Interactions between synthesis of platelet-activating factor and leukotriene B4 in isolated human polymorphonuclear leukocytes.
Topics: Arachidonate 5-Lipoxygenase; Azepines; Calcimycin; Chemotaxis, Leukocyte; Drug Interactions; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1993 |
Inhibitory effect of pemirolast, a novel antiallergic drug, on leukotriene C4 and granule protein release from human eosinophils.
Topics: Asthma; Blood Proteins; Calcimycin; Eosinophil Granule Proteins; Eosinophils; Humans; In Vitro Techniques; Leukotriene C4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyridines; Pyrimidinones; Ribonucleases; Secretory Rate | 1994 |
Inhibition of platelet aggregation by diterpene acids from Pinus massoniana resin.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Diterpenes; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Conformation; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1994 |
W-7, a calmodulin antagonist, primes the stimulation of human neutrophil respiratory burst by formyl peptides and platelet-activating factor.
Topics: Calcimycin; Calmodulin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Sulfonamides; Superoxides | 1994 |
Biosynthesis of platelet-activating factor and its 1O-acyl analogue by liver fat-storing cells.
Topics: Acetates; Calcimycin; Cells, Cultured; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lipids; Lipopolysaccharides; Liver; Platelet Activating Factor; Thrombin; Tritium | 1994 |
Priming for the synthesis of 5-lipoxygenase products in human blood ex vivo by human granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha.
Topics: Arachidonate 5-Lipoxygenase; Calcimycin; Complement C5a; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Recombinant Proteins; Tumor Necrosis Factor-alpha; Zymosan | 1994 |
Synthesis and release of platelet-activating factor and eicosanoids in human endothelial cells induced by different agonists.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Blood Platelets; Calcimycin; Cells, Cultured; Dinoprostone; Endothelins; Endothelium, Vascular; Epoprostenol; Histamine; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Serotonin; Thrombin; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
Inhibitory effects of azelastine hydrochloride on Ca2+ influx, actin polymerization and release of eosinophil cationic protein of an eosinophilic leukaemia cell line EoL-1.
Topics: Actins; Blood Proteins; Bucladesine; Calcimycin; Calcium-Transporting ATPases; Cell Differentiation; Culture Media; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Humans; Hypersensitivity; Immunoglobulin G; Inflammation; Leukemia, Eosinophilic, Acute; Leukemia, T-Cell; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Platelet Activating Factor; Polymers; Ribonucleases; Tumor Cells, Cultured | 1993 |
Studies on the metabolism of metallothionein and alkaline phosphatase of adult rat primary hepatocyte cultures: role of fetal calf serum and agonists of the phosphoinositide cascade.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Culture Media; Dexamethasone; Diglycerides; Liver; Metallothionein; Phosphatidylinositols; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Zinc | 1993 |
Production of oxygen radicals by fibroblasts and neutrophils from a patient with x-linked chronic granulomatous disease.
Topics: Calcimycin; Cells, Cultured; Child; Cytochrome b Group; Female; Fibroblasts; Granulomatous Disease, Chronic; Humans; Interleukin-1; Kinetics; Male; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Reference Values; Skin; Superoxides; Tumor Necrosis Factor-alpha; X Chromosome | 1993 |
Identification of phospholipase D (PLD) activity in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, Thin Layer; Glycerophospholipids; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
S-D-lactoylglutathione accumulation in activated human platelets.
Topics: Blood Platelets; Calcimycin; Glutathione; Humans; In Vitro Techniques; Lactoylglutathione Lyase; Platelet Activating Factor; Platelet Activation; Tetradecanoylphorbol Acetate; Thiolester Hydrolases; Thrombin | 1993 |
Effect of ibudilast, a novel antiasthmatic agent, on anaphylactic bronchoconstriction: predominant involvement of endogenous slow reacting substance of anaphylaxis.
Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Asthma; Bronchoconstriction; Bronchodilator Agents; Calcimycin; Chromones; Guinea Pigs; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyrazoles; Pyridines; SRS-A | 1993 |
Aggregation of killer whale platelets.
Topics: Adaptation, Physiological; Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Dolphins; Epinephrine; Female; Male; Platelet Activating Factor; Platelet Aggregation; Ristocetin; Thromboxane B2; Time Factors | 1993 |
1,3-Dioctanoylglycerol modulates arachidonate mobilization in human neutrophils and its inhibition by PGBx: evidence of a protein-kinase-C-independent role for diacylglycerols in signal transduction.
Topics: Arachidonic Acid; Calcimycin; Diglycerides; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Polymers; Prostaglandins B; Protein Kinase C; Signal Transduction; Superoxides | 1993 |
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
Topics: Arachidonic Acid; Calcimycin; Fatty Acids; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
Impaired superoxide anion, platelet-activating factor, and leukotriene B4 synthesis by neutrophils in cirrhosis.
Topics: Adult; Aged; Arachidonic Acid; Calcimycin; Female; Humans; Leukotriene B4; Liver Cirrhosis; Male; Mass Spectrometry; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Zymosan | 1993 |
Influence of isoproterenol and phosphodiesterase inhibitors on platelet-activating factor biosynthesis in the human neutrophil.
Topics: Acetyltransferases; Calcimycin; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Neutrophils; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Platelet Activating Factor | 1993 |
Prostaglandin E2 limits arachidonic acid availability and inhibits leukotriene B4 synthesis in rat alveolar macrophages by a nonphospholipase A2 mechanism.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats | 1993 |
Murine hypersensitivity pneumonitis: evidences for the role of eicosanoids and platelet activating factor.
Topics: Alveolitis, Extrinsic Allergic; Animals; Bronchoalveolar Lavage Fluid; Calcimycin; Disease Models, Animal; Eicosanoids; Female; Leukocyte Count; Lymphocytes; Macrophage Activation; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Saccharopolyspora; Specific Pathogen-Free Organisms | 1993 |
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Azepines; Blood; Calcimycin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Infusions, Intra-Arterial; Leukotriene B4; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Swine; Thromboxane B2; Triazoles | 1993 |
Immunoregulatory functions of paf-acether. IX. Modulation of apoptosis in an immature T cell line.
Topics: Apoptosis; Calcimycin; Cell Line; DNA; Humans; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; T-Lymphocytes | 1993 |
Increased plasma platelet-activating factor in children with acute asthmatic attacks and decreased in vivo and in vitro production of platelet-activating factor after immunotherapy.
Topics: Acute Disease; Animals; Asthma; Calcimycin; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Granulocytes; Humans; Immunotherapy; Mites; Osmolar Concentration; Platelet Activating Factor; Reference Values | 1993 |
Platelet activating factor increases intracellular calcium in isolated osteoclasts but does not modify bone resorption.
Topics: Animals; Bone Resorption; Calcimycin; Calcium; In Vitro Techniques; Intracellular Fluid; Ionomycin; Osteoclasts; Parathyroid Hormone; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 1993 |
Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs.
Topics: Animals; Blood Platelets; Calcimycin; GTP-Binding Proteins; Hemodynamics; Indomethacin; Injections, Intravenous; Lung; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Sodium Chloride; Swine; Thrombocytopenia; Thromboxane B2; Time Factors; Vasoconstriction; Virulence Factors, Bordetella | 1993 |
Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation.
Topics: Acyl Coenzyme A; Acylation; Acyltransferases; Adenosine Triphosphate; Calcimycin; Cell Membrane; Humans; Kinetics; Magnesium Chloride; Neutrophils; Platelet Activating Factor; Subcellular Fractions | 1993 |
Effect of docosahexaenoic acid on the generation of platelet-activating factor by eosinophilic leukemia cells, Eol-1.
Topics: Acetyltransferases; Arachidonic Acid; Calcimycin; Docosahexaenoic Acids; Eosinophils; Fatty Acids, Nonesterified; Humans; Interferon-gamma; Leukemia, Eosinophilic, Acute; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Tumor Cells, Cultured | 1993 |
Tumor necrosis factor-alpha potentiates phospholipase A2-stimulated release and metabolism of arachidonic acid in cultured intestinal epithelial cells (INT 407).
Topics: Arachidonic Acid; Calcimycin; Cell Line; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; Intestinal Mucosa; Lipid Metabolism; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1993 |
Platelet activating factor production in bovine cerebral microvascular endothelial cells and its drug inhibition.
Topics: Alkaloids; Animals; Benzylisoquinolines; Brain; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Isoquinolines; Microcirculation; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tetrahydroisoquinolines | 1993 |
Stimulation of platelet-activating factor synthesis by progesterone and A23187 in human spermatozoa.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Progesterone; Rabbits; Spermatozoa | 1993 |
Novel anti-inflammatory compounds prevent CD11b/CD18, alpha M beta 2 (Mac-1)-dependent neutrophil adhesion without blocking activation-induced changes in Mac-1.
Topics: Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Calcimycin; Cell Adhesion; Epitopes; Flow Cytometry; Humans; Ionophores; Leucine; Macrophage-1 Antigen; Molecular Sequence Data; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tumor Necrosis Factor-alpha; Up-Regulation | 1996 |
Production of PAF-acether by synovial fluid neutrophils in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Calcimycin; Humans; In Vitro Techniques; Ionophores; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Synovial Fluid | 1995 |
Production of platelet-activating factor by porcine brain microvascular endothelial cells in culture.
Topics: Animals; Aorta; Brain; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Microcirculation; Platelet Activating Factor; Swine | 1995 |
Role of cytokines, tyrosine kinase, and protein kinase C on production of superoxide and induction of scavenging enzymes in human leukocytes.
Topics: Adult; Bleomycin; Calcimycin; Catalase; Cytokines; Enzyme Induction; Female; Glutathione Peroxidase; Humans; Interferon-gamma; Interleukin-1; Lymphocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Regulation of platelet-activating factor production in gastric epithelial cells.
Topics: Animals; Calcimycin; Calcium; Carbachol; Epithelium; Gastric Mucosa; Histamine; Humans; Ionophores; Parasympathomimetics; Platelet Activating Factor; Rabbits; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Rat eosinophils: isolation and characterization of superoxide production.
Topics: Animals; Calcimycin; Cell Separation; Cytochalasin B; Eosinophils; Humans; In Vitro Techniques; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Increased hypodense eosinophils after activation with PAF-acether and calcium ionophore in asthmatic subjects.
Topics: Adult; Asthma; Calcimycin; Centrifugation, Density Gradient; Eosinophils; Female; Humans; Inflammation Mediators; Ionophores; Leukocyte Count; Male; Platelet Activating Factor | 1996 |
Priming effect of platelet activating factor on leukotriene C4 from stimulated eosinophils of asthmatic patients.
Topics: Adult; Aged; Asthma; Calcimycin; Chromatography, High Pressure Liquid; Eosinophils; Humans; In Vitro Techniques; Leukotriene C4; Male; Middle Aged; Platelet Activating Factor; Stimulation, Chemical | 1996 |
Histamine releasability of basophils and skin mast cells in chronic urticaria.
Topics: Adult; Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Cimetidine; Female; Histamine Release; Humans; Immunoglobulin E; Interleukin-3; Leukotriene C4; Male; Mast Cells; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Skin; Urticaria | 1996 |
Platelet-activating factor biosynthesis induced by various stimuli in human HaCaT keratinocytes.
Topics: Calcimycin; Calcium; Cell Line; Endothelin-1; Humans; Intracellular Membranes; Keratinocytes; Platelet Activating Factor; Stimulation, Chemical | 1996 |
Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro.
Topics: Aluminum Hydroxide; Animals; Antigens; Bronchoalveolar Lavage Fluid; Calcimycin; Dextrans; Eosinophils; Gels; Guinea Pigs; Indicators and Reagents; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Ionophores; Leukocyte Count; Leukotriene B4; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Respiratory System; Superoxides; Thromboxane B2 | 1996 |
Human platelet signaling defect characterized by impaired production of inositol-1,4,5-triphosphate and phosphatidic acid and diminished Pleckstrin phosphorylation: evidence for defective phospholipase C activation.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Female; Hemorrhagic Disorders; Humans; Inositol 1,4,5-Trisphosphate; Male; Middle Aged; Myosin Light Chains; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoproteins; Phosphoric Diester Hydrolases; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Processing, Post-Translational; Serotonin; Signal Transduction; Thrombin | 1996 |
The effects of EDRF/NO releasers or calcium ionophore A23187 on cyanide toxicity in mice.
Topics: Animals; Bradykinin; Calcimycin; Carbachol; Cyanides; Hydralazine; Ionophores; Lethal Dose 50; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activating Factor; Seizures; Substance P; Survival Rate | 1996 |
Inhibition of PAF synthesis by stimulated human polymorphonuclear leucocytes with cloricromene, an inhibitor of phospholipase A2 activation.
Topics: Acetyltransferases; Calcimycin; Chromonar; Diacylglycerol Cholinephosphotransferase; Enzyme Activation; Humans; In Vitro Techniques; Indicators and Reagents; Ionophores; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Aggregation Inhibitors | 1996 |
Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502.
Topics: Aluminum; Basophils; Calcimycin; Calcium; Depression, Chemical; Gene Expression Regulation; GTP-Binding Proteins; Humans; Interleukin-8; Ionophores; Leukocytes, Mononuclear; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines | 1996 |
Effect of the PAF-receptor antagonist SM-12502 on human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aluminum; Arachidonate 12-Lipoxygenase; Calcimycin; Calcium; Fatty Acids, Unsaturated; Gene Expression Regulation; GTP-Binding Proteins; Humans; Ionophores; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines; Thrombin | 1996 |
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Topics: Adult; Anti-Asthmatic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Azithromycin; Calcimycin; Cell Membrane; Clarithromycin; Erythromycin; Humans; Ionophores; Luminescent Measurements; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Roxithromycin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
High-density lipoprotein inhibits the synthesis of platelet-activating factor in human vascular endothelial cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyltransferases; Arachidonic Acid; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Histamine; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Phospholipases A; Platelet Activating Factor; Thrombin; Umbilical Veins | 1996 |
Changes in PAF (platelet-activating factor) production during cell cycle of yeast Saccharomyces cerevisiae.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Calcimycin; Cell Cycle; Haploidy; Microsomes; Phospholipases A; Phospholipids; Platelet Activating Factor; Saccharomyces cerevisiae | 1997 |
The role of platelet-activating factor-dependent transacetylase in the biosynthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine by stimulated endothelial cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetic Acid; Acetyltransferases; Adenosine Triphosphate; Animals; Calcimycin; Cattle; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Ionophores; Okadaic Acid; Phosphatidylcholines; Phospholipases A; Phosphoprotein Phosphatases; Platelet Activating Factor; Protein Phosphatase 1; Vanadates | 1997 |
Evidence that 85 kDa phospholipase A2 is not linked to CoA-independent transacylase-mediated production of platelet-activating factor in human monocytes.
Topics: Acyltransferases; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Benzenesulfonates; Calcimycin; Enzyme Inhibitors; Homosteroids; Humans; Monocytes; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Recombinant Proteins; Sesterterpenes; Sulfonamides; Terpenes; Urea | 1997 |
Eicosanoid production from porcine neutrophils and platelets: differential production with various agonists.
Topics: Animals; Blood Platelets; Calcimycin; Cell Communication; Complement C5a; Cytochalasin B; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxins; Male; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Recombinant Proteins; Swine; Thromboxane A2 | 1997 |
Studies of the nature of the binding by albumin of platelet-activating factor released from cells.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Azepines; Biological Availability; Blastocyst; Calcimycin; Cattle; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; Ionophores; Mice; Pepsin A; Peptide Mapping; Phospholipases A; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Binding; Protein Conformation; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Reagents; Triazoles; Trypsin | 1997 |
Activated mast cells release extracellular type platelet-activating factor acetylhydrolase that contributes to autocrine inactivation of platelet-activating factor.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcimycin; Ionophores; Kinetics; Male; Mast Cells; Mice; Mice, Inbred BALB C; Phospholipases A; Platelet Activating Factor; Polymerase Chain Reaction; Rats; Rats, Wistar; Recombinant Proteins; Stem Cell Factor | 1997 |
Identification of sn-2 acetyl glycerophosphocholines in human keratinocytes.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cell Line; Dexamethasone; Humans; Infant, Newborn; Ionophores; Keratinocytes; Kinetics; Mass Spectrometry; Platelet Activating Factor | 1997 |
Association of granular exocytosis with Ca(2+)-activated K+ channels in human eosinophils.
Topics: Calcimycin; Calcium; Chlorides; Eosinophils; Exocytosis; Humans; In Vitro Techniques; Ionomycin; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Patch-Clamp Techniques; Platelet Activating Factor; Potassium Channels; Potassium Channels, Calcium-Activated; Quinidine; Sodium; Thapsigargin | 1997 |
Platelet-activating factor stimulates calcium-dependent activation of protein-tyrosine kinase Syk in a human B cell line.
Topics: B-Lymphocytes; Calcimycin; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Precursors; Estrenes; Humans; Intracellular Signaling Peptides and Proteins; Ionophores; Pertussis Toxin; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Syk Kinase; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Platelet-activating factor induces cyclooxygenase-2 gene expression in corneal epithelium. Requirement of calcium in the signal transduction pathway.
Topics: Aniline Compounds; Animals; Azepines; Blotting, Northern; Blotting, Western; Calcimycin; Calcium; Cyclooxygenase 2; Enzyme Induction; Epithelium, Corneal; Fluorescent Dyes; Gene Expression; Ionophores; Isoenzymes; Microscopy, Confocal; Organ Culture Techniques; Peroxidases; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rabbits; RNA, Messenger; Signal Transduction; Thienopyridines; Triazoles; Xanthenes | 1997 |
Regulation of leukotriene and platelet-activating factor synthesis in human alveolar macrophages.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Arachidonic Acids; Asthma; Benzenesulfonates; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Ionophores; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Urea | 1997 |
Production, metabolism and effect of platelet-activating factor on the growth of the human K562 erythroid cell line.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetyl Coenzyme A; Calcimycin; Cell Division; Cells, Cultured; Erythroblasts; Erythrocytes; Humans; Ionophores; Leukemia, Erythroblastic, Acute; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Tumor Cells, Cultured | 1997 |
Enhancement of leukotriene B4 release in stimulated asthmatic neutrophils by platelet activating factor.
Topics: Adult; Arachidonate 5-Lipoxygenase; Asthma; Calcimycin; Calcium; Cells, Cultured; Cytosol; Female; Humans; Ionophores; Leukotriene B4; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Stimulation, Chemical | 1997 |
Possible mechanisms for the differential effects of high linoleate safflower oil and high alpha-linolenate perilla oil diets on platelet-activating factor production by rat polymorphonuclear leukocytes.
Topics: Acyltransferases; alpha-Linolenic Acid; Animals; Calcimycin; Dietary Fats, Unsaturated; Fatty Acids, Nonesterified; In Vitro Techniques; Ionophores; Linoleic Acid; Male; Neutrophils; Phenylpropionates; Plant Oils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene B4; Safflower Oil | 1997 |
Metabolic fate of platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) in FRTL5 cells.
Topics: Acetylation; Animals; Calcimycin; Cell Line; Kinetics; Phenylmethylsulfonyl Fluoride; Phosphatidylcholines; Plasmalogens; Platelet Activating Factor; Radioisotope Dilution Technique; Rats; Thyroid Gland; Tritium | 1998 |
Platelet-activating factor increases leukotriene B4 release in stimulated alveolar macrophages from asthmatic patients.
Topics: Adult; Arachidonate 5-Lipoxygenase; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Cytosol; Female; Humans; Inflammation Mediators; Ionophores; Leukotriene B4; Macrophages, Alveolar; Male; Middle Aged; Osmolar Concentration; Platelet Activating Factor; Reference Values | 1998 |
Effect of replacing a high linoleate oil with a low linoleate, high alpha-linolenate oil, as compared with supplementing EPA or DHA, on reducing lipid mediator production in rat polymorphonuclear leukocytes.
Topics: alpha-Linolenic Acid; Animals; Calcimycin; Dietary Fats, Unsaturated; Docosahexaenoic Acids; Eicosanoids; Eicosapentaenoic Acid; Ionophores; Linoleic Acid; Male; Neutrophils; Phospholipids; Plant Oils; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Safflower Oil | 1998 |
Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Dronabinol; Endocannabinoids; Immune System; Indomethacin; Ionophores; Lipopolysaccharides; Macrophages; Mice; Platelet Activating Factor; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug | 1998 |
Soluble vascular cell adhesion molecule (VCAM)-Fc fusion protein induces leukotriene C4 secretion in platelet-activating factor-stimulated eosinophils.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cell Adhesion; Drug Synergism; Eosinophils; Humans; Immunoglobulin Fc Fragments; Ionophores; Leukotriene C4; Mice; Molecular Sequence Data; Peptides, Cyclic; Platelet Activating Factor; Recombinant Fusion Proteins; Stimulation, Chemical; Vascular Cell Adhesion Molecule-1 | 1999 |
Identification and pharmacological characterization of platelet-activating factor and related 1-palmitoyl species in human inflammatory blistering diseases.
Topics: Animals; Binding, Competitive; Blister; Blotting, Northern; Calcimycin; Calcium; Dose-Response Relationship, Drug; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerylphosphorylcholine; Humans; Inflammation; KB Cells; Pemphigoid, Bullous; Phosphatidylcholines; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Wistar; Retroviridae; Time Factors; Transduction, Genetic | 1998 |
Intracellular mechanisms of hydrogen peroxide-mediated neutrophil adherence to cultured human endothelial cells.
Topics: Azepines; Calcimycin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydrogen Peroxide; In Vitro Techniques; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
Modulation of mast cell activity by a peptide agonist of the thrombin receptor: role of nitric oxide.
Topics: Animals; Calcimycin; Inflammation; Mast Cells; Nitric Oxide; Peptide Fragments; Peritoneum; Platelet Activating Factor; Rats; Receptors, Thrombin; Thrombin | 1999 |
Modulation of PAF production by incorporation of arachidonic acid and eicosapentaenoic acid in phospholipids of human leukemic monocyte-like cells THP-1.
Topics: Acetates; Arachidonic Acid; Calcimycin; Eicosapentaenoic Acid; Humans; Ionophores; Leukemia, Monocytic, Acute; Phospholipids; Platelet Activating Factor; Tumor Cells, Cultured | 2000 |
Effects of platelet activating factor on capacitation and acrosome reaction in mouse spermatozoa.
Topics: Acrosome Reaction; Animals; Calcimycin; Ionophores; Male; Mice; Platelet Activating Factor; Sperm Capacitation; Spermatozoa | 2000 |
Combined defect in membrane expression and activation of platelet GPIIb--IIIa complex without primary sequence abnormalities in myeloproliferative disease.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Antibodies, Monoclonal; Binding Sites; Blood Platelets; Calcimycin; Diglycerides; DNA, Complementary; Enzyme Activators; Flow Cytometry; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Ionophores; Macrophage-1 Antigen; Male; Myeloproliferative Disorders; Neutrophils; Peptides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Polymerase Chain Reaction; Protein Binding; Protein Kinase C; Receptors, Thrombin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction | 2000 |
A23187 causes release of inositol phosphates from cultured rat Kupffer cells.
Topics: Animals; Calcimycin; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Inositol Phosphates; Ionophores; Kupffer Cells; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Intraleucocyte platelet-activating factor levels in desmopressin-treated patients with haemophilia A and von Willebrand disease.
Topics: Adolescent; Adult; Calcimycin; Child; Child, Preschool; Deamino Arginine Vasopressin; Female; Hemophilia A; Hemostatics; Humans; Ionophores; Leukocytes; Male; Platelet Activating Factor; Treatment Outcome; von Willebrand Diseases | 2001 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Measurement of the activation of equine platelets by use of fluorescent-labeled annexin V, anti-human fibrinogen antibody, and anti-human thrombospondin antibody.
Topics: Animals; Annexin A5; Antibodies; Blood Platelets; Calcimycin; Fibrinogen; Flow Cytometry; Fluorescent Dyes; Horses; Ionophores; Platelet Activating Factor; Platelet Activation; Thrombospondins | 2002 |
Effects of formaldehyde fixation on equine platelets using flow cytometric methods to evaluate markers of platelet activation.
Topics: Adenosine Diphosphate; Animals; Annexin A5; Blood Platelets; Calcimycin; Fixatives; Flow Cytometry; Formaldehyde; Horses; Ionophores; Platelet Activating Factor; Platelet Activation | 2002 |
Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils. Evidence for different arachidonate pools.
Topics: Acyltransferases; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ionophores; Leukotriene B4; Leukotrienes; Lipid Metabolism; Lipoxygenase Inhibitors; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor | 2002 |
Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases.
Topics: Acetyltransferases; Acyltransferases; Calcimycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Platelet Activating Factor | 2002 |
Overexpression of phospholipid hydroperoxide glutathione peroxidase modulates acetyl-CoA, 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity.
Topics: Acetyl Coenzyme A; Acetyltransferases; Alkaline Phosphatase; Animals; Calcimycin; Glutathione Peroxidase; Hydrogen Peroxide; Kinetics; L Cells; Leukemia, Basophilic, Acute; Mice; Mitochondria; Mitogen-Activated Protein Kinases; Phospholipid Hydroperoxide Glutathione Peroxidase; Phosphorylation; Platelet Activating Factor; Rats; Reactive Oxygen Species; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 2002 |
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin | 2002 |
Platelet-activating factor and P-selectin activities in thrombotic and nonthrombotic Behçet's patients.
Topics: Adult; Behcet Syndrome; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Female; Humans; Ionophores; Leukocytes; Male; P-Selectin; Platelet Activating Factor; Venous Thrombosis | 2005 |
Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation.
Topics: Benzoquinones; Blood Platelets; Calcimycin; Humans; Indomethacin; Ionophores; Lactams, Macrocyclic; Platelet Activating Factor; Platelet Aggregation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Thromboxane A2; Verapamil | 2004 |
Meconium enhances platelet-activating factor and tumor necrosis factor production by rat alveolar macrophages.
Topics: Animals; Animals, Newborn; Calcimycin; Cells, Cultured; Female; Lipopolysaccharides; Macrophages, Alveolar; Male; Meconium; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2004 |
Platelet-activating factor acts on cortisol secretion by perfused guinea-pig adrenals via calcium-/phospholipid-dependent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcium; Colforsin; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Drug Synergism; Enzyme Activation; Guinea Pigs; Hydrocortisone; Ionophores; Isoquinolines; Male; Perfusion; Phospholipid Ethers; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyridinium Compounds; Receptors, G-Protein-Coupled; Secretory Rate | 2005 |
Differential platelet-activating factor synthesis by monocytes and polymorphonuclear leukocytes from subjects with localized aggressive periodontitis.
Topics: Adult; Analysis of Variance; Animals; Calcimycin; Case-Control Studies; Cattle; Confidence Intervals; Humans; Monocytes; Neutrophils; Periodontitis; Platelet Activating Factor | 2007 |
Cross-regulation of cortisol secretion by adrenocorticotropin and platelet-activating factor in perfused guinea pig adrenals.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcimycin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Hydrocortisone; Ionophores; Male; Organ Culture Techniques; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, G-Protein-Coupled; Signal Transduction | 2007 |
Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses.
Topics: Animals; Aspirin; Azepines; Benzamides; Blood Platelets; Calcimycin; Female; Horses; Leukocytes; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; Serotonin; Thromboxane A2; Time Factors; Triazoles; Tryptamines; Vasoconstriction | 2008 |
Effects of acrolein on leukotriene biosynthesis in human neutrophils.
Topics: Acrolein; Air Pollutants; Arachidonate 5-Lipoxygenase; Calcimycin; Dose-Response Relationship, Drug; Drug Interactions; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotrienes; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases | 2008 |
Persistency and pathway of isoflurane-induced inhibition of superoxide production by neutrophils.
Topics: Anesthetics, Inhalation; Animals; Calcimycin; Dogs; Isoflurane; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF, PMA or A23187 in C6 glioma cells.
Topics: Animals; Calcimycin; Cell Line, Tumor; Enzyme Activation; Fluorenes; Histamine; Phosphatidylcholines; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipase D; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 2013 |
Inhibition of platelet-activating factor (PAF)-induced platelet aggregation by fatty acids from human saliva.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcimycin; Fatty Acids; Humans; Ionophores; Mammals; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Saliva; Thrombin | 2022 |