1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with aspirin in 154 studies
| Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Studies (aspirin) | Trials (aspirin) | Recent Studies (post-2010) (aspirin) |
|---|---|---|---|---|---|
| 9,156 | 187 | 552 | 48,947 | 6,817 | 13,778 |
| Protein | Taxonomy | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) | aspirin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.35 | |
| Integrin beta-3 | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.8252 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 1.375 | |
| Integrin alpha-IIb | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.271 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 2.4 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 2.15 | |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | 0.3 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 2.4 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.35 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4081 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (51.30) | 18.7374 |
| 1990's | 53 (34.42) | 18.2507 |
| 2000's | 14 (9.09) | 29.6817 |
| 2010's | 8 (5.19) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, T; Matsukawa, H; Toyoda, Y; Tsuriya, Y; Yanagihara, Y | 1 |
| Asako, H; Granger, DN; Kubes, P; Wallace, J; Wolf, RE | 1 |
| Bodis, J; Tinneberg, HR | 1 |
| Misso, NL; Stewart, GA; Taylor, ML; Thompson, PJ | 2 |
| Burke, V; Douglas, AJ; McCulloch, RK; Mori, TA; Vandongen, R | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamanaka, S; Yukimura, T | 1 |
| Dunoyer-Geindre, S; Girard, JP; Gumowski, PI; Ludi, F; Perez, T; Terki, N | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Vapaatalo, H | 1 |
| Amorim, CZ; Cordeiro, RS; Henriques, MG; Vargaftig, BB; Weg, VB | 1 |
| Teng, CM; Wang, JP | 1 |
| Hattori, H; Kishimoto, S; Miyatake, A; Okuda, Y; Takashima, T; Tsuyuguchi, I; Yamatodani, A | 1 |
| Bureau, M; Dry, J; Lefort, J; Vargaftig, BB; Vincent, D | 1 |
| Barrigón, S; Salinas, P | 1 |
| Grunfeld, S; Han, E; Joseph, R; Welch, KM | 1 |
| Takahashi, O | 1 |
| Ammit, AJ; O'Neill, C | 1 |
| Kimura, I; Kimura, M; Kobayashi, S; Nakagawa, M | 1 |
| Imanishi, M; Miura, K; Okumura, M; Shimmen, T; Yamamoto, K; Yamanaka, S; Yamashita, Y; Yukimura, T | 1 |
| Ahmed, Y; Elder, MG; Sullivan, MH | 1 |
| Grunfeld, S; Han, E; Joseph, R; Robertson, W | 1 |
| Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
| Kakishita, E; Nagai, K; Oura, Y; Suehiro, A | 1 |
| Dujovne, CA; Harris, WS; Silveira, S | 1 |
| Alessandri, C; Balsano, F; Cordova, C; Ghiselli, A; Iuliano, L; Pratico, D; Violi, F | 1 |
| Bauer, JA; Fritz, H; Hafner, M | 1 |
| Hamano, S; Ikeda, S; Kikuchi, S; Kojima, M; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y | 1 |
| Bassot, S; Chignard, M; Ferrer-Lopez, P; Laurent, P; Renesto, P; Schattner, M | 1 |
| Adi, S; Feingold, KR; Fiers, W; Grunfeld, C; Moser, A; Soued, M | 1 |
| Addonizio, VP; Berkowitz, HD; Cottrell, ED; Ellison, N; Fisher, CA; Kappa, JR; Sobel, M | 1 |
| Jackson, SP; Salem, HH | 1 |
| Alessandri, C; Balsano, F; Ghiselli, A; Guzzo, A; Praticò, D; Violi, F | 1 |
| de la Motte, CA; DiCorleto, PE | 1 |
| Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P | 1 |
| Bauer, JA; Conzen, P; Fritz, H; Wurster, K | 1 |
| Baker, RC; Fish, HT; Fitzpatrick, FA | 1 |
| Gentry, PA; Liptrap, RM; Niemuller, C; Ross, ML | 1 |
| Imura, Y; Iwasaki, K; Nishikawa, K; Shibouta, Y; Terashita, Z | 1 |
| D'Andrea, G; Joseph, R; Welch, KM | 1 |
| McCulloch, RK; Rouse, IL; Summers, J; Vandongen, R | 1 |
| Beck, G; Brzozowski, T; Drozdowicz, D; Garlicki, J; Konturek, SJ | 1 |
| Bahr, T; Becker, K; Förster, W; Grupe, R; Lueddeckens, G; Schaper, U; Scheuch, DW | 1 |
| Benveniste, J; Bossant, MJ; Denizot, Y; Dulioust, A; Pitton, C; Salem, P; Thomas, Y | 1 |
| McDonald, JW; Smallbone, BW; Taylor, NE | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Driscoll, EM; Jackson, CV; Kunkel, SL; Lucchesi, BR; Schumacher, WA | 1 |
| Aglietta, M; Breviario, F; Bussolino, F; Dejana, E; Mantovani, A; Tetta, C | 1 |
| Frölich, JC; Küster, LJ | 2 |
| Flower, RJ | 1 |
| Dejana, E; Prosdocimi, M; Zanetti, A; Zatta, A | 1 |
| Armstrong, RA; Jones, RL; Wilson, NH | 1 |
| Altman, R; Cacchione, R; Rouvier, J; Scazziota, A | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Braquet, P; Clostre, F; Etienne, A; Mencia-Huerta, JM | 1 |
| Finiasz, M; Gimeno, M; Lazzari, MA; Schattner, MA | 1 |
| Altman, R; Scazziota, A | 1 |
| Alexandre, A; Deana, R; Doni, MG; Padoin, E | 1 |
| Wallace, JL; Whittle, BJ | 1 |
| Cordeiro, RS; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Mest, HJ; Riedel, A | 1 |
| Adnot, S; Joseph, D; Vargaftig, BB | 1 |
| Imura, Y; Nishikawa, K; Shino, A; Terashita, Z | 1 |
| Picado, C; Plaza, V | 1 |
| Anderson, GP; Fennessy, MR; White, HL | 1 |
| Azami, K; Hasegawa, T; Hoshi, M; Ohura, T; Ono, I; Tsutsumi, M | 1 |
| Altman, R; Funes, JC; Scazziota, A | 1 |
| Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G | 1 |
| Beck, G; Brzozowski, T; Drozdowicz, D; Konturek, SJ | 1 |
| Braquet, P; Freitas, JC; Lavaud, P; Mencia-Huerta, JM; Rodrigue, F | 1 |
| Hansen, BF; Hansen, JF | 1 |
| Altman, R; Dujovne, C; Scazziota, A | 1 |
| Benveniste, J; Brink, C; Brunelleschi, S; Haye-Legrand, I; Labat, C; Norel, X | 1 |
| Krzanowski, M; Musial, J; Nizankowska, E; Szczeklik, A | 1 |
| de Souza, V; Matthys, H; Menz, G; Schäufele, A; Schmitz-Schumann, M; Virchow, C; von Felten, A | 1 |
| Fouque, F; Vargaftig, BB | 2 |
| Castro, HC; Cordeiro, RS; Lima, MC; Martins, MA; Neto, F; Silva, PM; Vargaftig, BB | 1 |
| Barbui, T; Cortelazzo, S; de Gaetano, G; Viero, P | 1 |
| Cerletti, C; de Gaetano, G; Lauri, D | 2 |
| Filep, J; Frölich, JC; Küster, LJ | 1 |
| Rainsford, KD | 1 |
| Lefort, J; Lellouch-Tubiana, A; Pfister, A; Pirotzky, E; Vargaftig, BB | 1 |
| Canciani, MT; Cattaneo, M; Mannucci, PM | 1 |
| Carriero, MR; Cerletti, C; de Gaetano, G | 1 |
| Neilsen, NR; Slauson, DO; Wimberly, HC | 1 |
| Benveniste, J; Hadji, L; Mencia-Huerta, JM | 1 |
| Rao, GH; Reddy, KR; Schmid, HH; White, JG | 1 |
| Hallam, TJ; Rink, TJ; Sanchez, A | 1 |
| Lapetina, EG; Siess, W; Weber, PC | 1 |
| Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Nina, M; Packham, MA | 1 |
| Huston, L; Leid, RW; Liggitt, HD | 1 |
| O'Flaherty, JT; Stimler, NP | 1 |
| Arnoux, B; Benveniste, J; Denjean, A; Lockhart, A; Masse, R | 1 |
| Nunn, B | 1 |
| Bienenstock, J; Cazenave, JP; Denburg, JA; Kinlough-Rathbone, RL; Williams, DB | 1 |
| Benveniste, J; Chignard, M; Le Couedic, JP; Vargaftig, BB | 1 |
| Ferreira, SH; Vargaftig, BB | 1 |
| Rao, GH; White, JG | 1 |
| Akkerman, JW; De Haas, GH; Gorter, G; Kloprogge, E | 1 |
| Conard, J; Horellou, MH; Lecrubier, C; Samama, M | 1 |
| Leid, RW; Suquet, CM | 1 |
| Breddin, HK; Mutschler, E; Simrock, R; Spahn, H | 1 |
| Benveniste, J; Chignard, M; Lefort, J; Vargaftig, BB | 1 |
| Byers, LW; Chesney, CM; Muirhead, EE; Pifer, DD | 1 |
| Barton, M; Lefort, J; Prancan, A; Vargaftig, BB | 1 |
| Benveniste, J; Fouque, F; Odiot, J; Vargaftig, BB | 1 |
| Becker, K; Brodde, OE; Giessler, C; Heinroth-Hoffmann, I; Pönicke, K | 1 |
| Conroy, MC; Finkel, M; Grabow, D; Lesch, M; Low, J; Metz, A; Schrier, D; Sommers, C; Wallace, J | 1 |
| Adams, DM; Peaceman, AM; Silver, RK | 1 |
| Rezaul, K; Sada, K; Taniguchi, T; Yamamura, H; Yanagi, S | 1 |
| Flores, NA; Goulielmos, NV; Seghatchian, MJ; Sheridan, DJ | 1 |
| Evans, RJ; Hayes, LJ; Heath, MF; Littler, RM; McEvoy, RJ; Poole, AW | 1 |
| Evans, RJ; Jarvis, GE | 2 |
| Alberola, ML; Caramelo, C; Casado, S; Esteban, A; López-Farré, A; Millás, I; Montón, M | 1 |
| Mahmood, F; Rahman, NN; Saeed, SA; Simjee, RU | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 1 |
| Bernat, A; Herbert, JM | 1 |
| Anderson, DC; Granger, DN; Kvietys, PR; McIntire, LV; Takemura, T; Wolf, RE; Yoshida, N | 1 |
| Farnaz, S; Malik, A; Saeed, SA; Simjee, RU | 1 |
| Altman, R; Budd, SE; Chernoff, SB; Dollar, LE; Zucker, ML | 1 |
| Hirafuji, M; Shinoda, H | 1 |
| Cheng, NN; Mabuchi-Itoh, K; Sugiura, T; Waku, K | 1 |
| Caplan, MS; O'Connell, PD; Silver, RK | 1 |
| Stewart, GA; Taylor, ML; Thompson, PJ | 1 |
| Arnout, J; Deckmyn, H; Hoet, B; Kienast, J; Pfliegler, G; Vermylen, J; Wittevrongel, C | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Cole, AT; Hawkey, CJ; Heptinstall, S; May, JA | 1 |
| Ariga, T; Kobayashi, A; Kubota, K; Lim, H; Seki, T | 1 |
| Brasch, F; Falk, S; Göggel, R; Heydasch, U; Müller, KM; Uhlig, S; Wendel, A | 1 |
| Feijge, MA; Heemskerk, JW; Keularts, IM; van Gorp, RM; Vuist, WM | 1 |
| Bath, P; Heptinstall, S; Zhao, L | 1 |
| Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Chen, ZH; Hao, XJ; Li, L; Shen, YM; Shen, ZQ; Yang, XS; Zuo, GY | 1 |
| Budaj, A; Copland, I; Eikelboom, JW; Johnston, M; Maciejewski, P; Weitz, JI; Yusuf, S; Zhao, F | 1 |
| Furukawa, M; Ogura, M; Tsuji, H; Tsutsumi, T; Yamashita, T | 1 |
| Chang, FR; Du, YC; Kuo, RY; Patnam, R; Wang, WY; Wu, CC; Wu, YC | 1 |
| Buchanan, MR | 1 |
| Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF | 1 |
| Andersson, J; Bengtsson, T; Grenegård, M; Kälvegren, H | 1 |
| Fox, SC; Heptinstall, S; White, AE; Wilcox, RG; Xavier, RG | 1 |
| Bailey, SR; Cunningham, FM; Elliott, J; Menzies-Gow, NJ; Sepulveda, MF | 1 |
| Farhan, S; Glogar, D; Gyöngyösi, M; Hemetsberger, H; Hemetsberger, R; Huber, K; Pavo, I; Petrasi, Z; Posa, A; Sperker, W; Strehblow, C | 1 |
| Deev, AD; Dobrovol'skiĭ, AB; Katkova, OV; Laguta, PS; Panchenko, EP; Titaeva, EV | 1 |
| Armstrong, PC; Chan, MV; Kirkby, NS; Papalia, F; Warner, TD | 1 |
| Dong, CM; Jia, XQ; Qin, J; Zhang, L | 1 |
| Boyce, JA; Laidlaw, TM | 1 |
| Barinov, EF; Mamedaliyeva, S; Tverdokhleb, TA | 1 |
| Smith, LJ | 1 |
| Chen, MH; Liu, J; Luo, M; Peng, C; Pu, ZH; Xie, XF; Xiong, L; Zhou, QM | 1 |
| Ivashin, DS; Olkhovsky, IA; Stolyar, MA | 1 |
4 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and aspirin
| Article | Year |
|---|---|
[Asthma and platelets].
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Drug Tolerance; Humans; Platelet Activating Factor | 1988 |
[Unstable angina pectoris, acute myocardial infarct, sudden heart death. Patho-anatomy and pathophysiology].
Topics: Angina Pectoris; Angina, Unstable; Aspirin; Calcium Channel Blockers; Coronary Angiography; Coronary Vessels; Death, Sudden; Endoscopy; Heparin; Humans; Myocardial Infarction; Platelet Activating Factor | 1987 |
Understanding prostaglandin metabolites and platelet-activating factor in the pathophysiology and treatment of the antiphospholipid syndrome.
Topics: Abortion, Habitual; Antiphospholipid Syndrome; Aspirin; Female; Humans; Platelet Activating Factor; Pregnancy; Prostaglandin Antagonists; Prostaglandins | 1995 |
Platelets in patients with aspirin-exacerbated respiratory disease.
Topics: Animals; Aspirin; Asthma, Aspirin-Induced; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Clinical Trials as Topic; Eosinophils; Gene Expression; Humans; Leukotrienes; Oxazoles; Piperazines; Platelet Activating Factor; Platelet Activation; Prasugrel Hydrochloride; Receptors, Leukotriene; Thiophenes; Thromboxane A2 | 2015 |
9 trial(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and aspirin
| Article | Year |
|---|---|
Effect of ticlopidine and aspirin on platelet ionized calcium in ischemic stroke.
Topics: Aspirin; Blood Platelets; Brain Ischemia; Calcium; Collagen; Humans; In Vitro Techniques; Platelet Activating Factor; Thrombin; Ticlopidine | 1991 |
Role of thromboxane A2 as a mediator of platelet-activating-factor-induced aggregation of human platelets.
Topics: Adult; Aspirin; Collagen; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2 | 1989 |
Bleeding time and PAF-acether-induced platelet aggregation in atopy.
Topics: Adult; Aspirin; Asthma; Bleeding Time; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Function Tests; Rhinitis, Allergic, Seasonal | 1987 |
[Reversible inhibition of thrombocyte stimulation by acetylsalicylic acid and its role in antithrombotic therapy].
Topics: Administration, Oral; Adult; Aspirin; Blood Platelets; Fibrinolytic Agents; Humans; Male; Platelet Activating Factor | 1983 |
Effect of diltiazem and low-dose aspirin on platelet aggregation and ATP release induced by paired agonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Drug Synergism; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1993 |
Platelet responses to several agonists and combinations of agonists in whole blood: a placebo controlled comparison of the effects of a once daily dose of plain aspirin 300 mg, plain aspirin 75 mg and enteric coated aspirin 300 mg, in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Coagulants; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Placebos; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Streptokinase; Tablets, Enteric-Coated | 1997 |
Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes.
Topics: Antigens; Aspirin; Biomarkers; Blood Coagulation; Blood Coagulation Factors; Clopidogrel; Cohort Studies; Coronary Disease; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome; von Willebrand Factor | 2002 |
[Aspirin resistance in patients with stable ischemic heart disease].
Topics: Aged; Aspirin; Coronary Angiography; Drug Monitoring; Drug Resistance; Echocardiography, Transesophageal; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Platelet Activating Factor; Risk Factors; Severity of Illness Index; Thromboxane B2; Treatment Outcome | 2010 |
[Changes in coagulation and fibrinolysis in the patients with coronary heart disease in acute period and effect of drug intervention].
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Blood Coagulation; Case-Control Studies; Clopidogrel; Coronary Disease; Double-Blind Method; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activating Factor; Prospective Studies; Ticlopidine; Tissue Plasminogen Activator; von Willebrand Factor | 2012 |
141 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and aspirin
| Article | Year |
|---|---|
[Effect of tazanolast on platelet activating factor-induced airway hyperresponsiveness in guinea pigs].
Topics: Animals; Aspirin; Bronchial Hyperreactivity; Guinea Pigs; Histamine Antagonists; Male; ortho-Aminobenzoates; Platelet Activating Factor; Tetrazoles | 1992 |
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Splanchnic Circulation; Venules | 1992 |
Migraine.
Topics: Aspirin; Female; Humans; Menstrual Cycle; Migraine Disorders; Platelet Activating Factor | 1992 |
The effects of varying doses of aspirin on human platelet activation induced by PAF, collagen and arachidonic acid.
Topics: Adenosine Triphosphate; Adult; Arachidonic Acid; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Sex Factors | 1992 |
Differential effect of aspirin on platelet aggregation in IDDM.
Topics: Adult; Aspirin; Blood Pressure; Cholesterol; Collagen; Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Humans; Linoleic Acid; Linoleic Acids; Male; Membrane Fluidity; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Reference Values; Thromboxane B2 | 1992 |
Putative mechanism of hypotensive action of platelet-activating factor in dogs.
Topics: Animals; Aspirin; Blood Pressure; Cardiac Output; Dogs; Female; Hemodynamics; Hypotension; Male; Platelet Activating Factor; Prostaglandins; Thromboxane A2; Time Factors; Vasodilation; Veins | 1992 |
PAF acether release on antigenic challenge. A method for the investigation of drug allergic reactions.
Topics: Antigens; Aspirin; Drug Hypersensitivity; Humans; Immunoglobulin E; Leukocytes; Lidocaine; Lymphocyte Activation; Penicillins; Platelet Activating Factor; Platelet Aggregation; Predictive Value of Tests; Quinolinium Compounds; Radioallergosorbent Test; Sensitivity and Specificity; Skin Tests; Trimethoprim, Sulfamethoxazole Drug Combination | 1992 |
Platelet-activating factor impairs mucociliary transport and increases plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Aspirin; Bronchi; Female; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Mucociliary Clearance; Platelet Activating Factor; Platelet Aggregation; Respiratory Mechanics | 1991 |
Effect of PAF-acether antagonists on active anaphylactic mouse paw edema.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Anaphylaxis; Animals; Aspirin; Azepines; Cimetidine; Dexamethasone; Edema; Male; Meclizine; Methysergide; Mice; Ovalbumin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prednisolone; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetrazoles; Triazoles | 1991 |
Effects of anti-inflammatory drugs on rat hind-paw swelling caused by phospholipase A2 from Naja naja atra venom.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Edema; Elapid Venoms; Histamine; Kinins; Leukocytes, Mononuclear; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1991 |
Basophil histamine release by platelet-activating factor in aspirin-sensitive subjects with asthma.
Topics: Adult; Aged; Aspirin; Asthma; Basophils; Cytochalasin B; Dexamethasone; Female; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Male; Middle Aged; Platelet Activating Factor | 1990 |
Dissociation between LPS-induced bronchial hyperreactivity and airway edema in the guinea-pig.
Topics: Animals; Aspirin; Azepines; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Escherichia coli; Guinea Pigs; Lipopolysaccharides; Macrophages; Male; Neutrophils; Platelet Activating Factor; Pulmonary Edema; Pyrilamine; Respiratory Hypersensitivity; Triazoles | 1991 |
Protective effects of dazmegrel on the PAF potential of ouabain-induced cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Disease Models, Animal; Drug Synergism; Female; Guinea Pigs; Imidazoles; Lysine; Ouabain; Platelet Activating Factor; Thromboxane-A Synthase | 1991 |
[Effect of chronic antiplatelet treatment on platelet activating factor-induced platelet activity in stroke].
Topics: Adenosine Triphosphate; Adult; Aspirin; Calcium; Cerebrovascular Disorders; Female; Humans; Ibuprofen; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation | 1991 |
Some properties of rat platelet aggregation and effects of butylated hydroxytoluene, warfarin and aspirin.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Butylated Hydroxytoluene; Collagen; Epinephrine; Male; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains; Ristocetin; Warfarin | 1991 |
Rapid and selective measurement of platelet-activating factor using a quantitative bioassay of platelet aggregation.
Topics: Animals; Aspirin; Biological Assay; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; In Vitro Techniques; Kinetics; Lactones; Male; Phosphoenolpyruvate; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Pyruvate Kinase; Rabbits | 1991 |
Effects of prostaglandin E2 and cyclooxygenase inhibitors on clustering and level of nicotinic acetylcholine receptor in mouse myotubes co-cultured with spinal cord explant.
Topics: Animals; Aspirin; Cell Communication; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Indomethacin; Kinetics; Masoprocol; Mice; Mice, Inbred Strains; Muscles; Organ Culture Techniques; Platelet Activating Factor; Receptors, Nicotinic; Spinal Cord | 1991 |
Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; Femoral Artery; Heart Rate; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney; Male; Platelet Activating Factor; Prostaglandins; Pyridinium Compounds; Renal Circulation; Time Factors; Vasoconstriction | 1991 |
Increased platelet turnover in a patient with previous recurrent pre-eclampsia and failure of aspirin therapy. Case report.
Topics: Adult; Aspirin; Blood Platelets; Female; Humans; Platelet Activating Factor; Platelet Aggregation; Pre-Eclampsia; Pregnancy; Thromboxane B2 | 1991 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Inhibitory effect of vitamin E (alpha-tocopherol) on spontaneous platelet aggregation in whole blood.
Topics: Adenosine Diphosphate; Adult; Aspirin; Creatine Kinase; Drug Synergism; Humans; In Vitro Techniques; Male; Phosphocreatine; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Verapamil; Vitamin E | 1990 |
The combined effects of N-3 fatty acids and aspirin on hemostatic parameters in man.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Collagen; Depression, Chemical; Drug Synergism; Fish Oils; Hemostasis; Humans; Male; Platelet Activating Factor; Platelet Aggregation | 1990 |
Inhibition of cyclooxygenase-independent platelet aggregation by low vitamin E concentration.
Topics: alpha-Tocopherol; Apyrase; Aspirin; Blood Platelets; Collagen; Epinephrine; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Tocopherols; Vitamin E | 1990 |
Balanced antiinflammation: the combined application of a PAF inhibitor and a cyclooxygenase inhibitor blocks the inflammatory take-off after burns.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Burns; Cyclooxygenase Inhibitors; Diterpenes; Drug Combinations; Ginkgolides; Lactones; Platelet Activating Factor; Swine; Wound Healing | 1990 |
Effect of a thromboxane A2 synthetase inhibitor (OKY-046.HCl) on airway hyperresponsiveness in guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Airway Resistance; Animals; Antigens; Aspirin; Bronchoalveolar Lavage Fluid; Guinea Pigs; Leukotriene E4; Methacrylates; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Physostigmine; Platelet Activating Factor; Propranolol; Respiratory System; SRS-A; Thromboxane B2; Thromboxane-A Synthase | 1990 |
Activation of human platelets by C5a-stimulated neutrophils: a role for cathepsin G.
Topics: Amino Acid Sequence; Aspirin; Azepines; Blood Platelets; Cathepsin G; Cathepsins; Complement C5a; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pancreatic Elastase; Platelet Activating Factor; Platelet Activation; Protease Inhibitors; Recombinant Proteins; Serine Endopeptidases; Serotonin; Triazoles | 1990 |
Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6.
Topics: Animals; Aspirin; Azepines; Cholesterol; Fatty Acids; Ibuprofen; Interleukin-6; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oleic Acid; Oleic Acids; Pentoxifylline; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Triazoles; Triglycerides; Tumor Necrosis Factor-alpha | 1990 |
Carotid endarterectomy in patients with heparin-induced platelet activation: comparative efficacy of aspirin and iloprost (ZK36374).
Topics: Aged; Aspirin; beta-Thromboglobulin; Cardiovascular Agents; Carotid Arteries; Drug Evaluation; Endarterectomy; Epoprostenol; Fibrinopeptide A; Heparin; Humans; Iloprost; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Platelet Factor 4; Preoperative Care; Thrombosis | 1987 |
Platelet aggregating activity in the plasma of patients with established thrombosis.
Topics: Adult; Aged; Aspirin; Benzamidines; Blood Coagulation Factors; Edetic Acid; Humans; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thrombocytopenia; Thrombosis; Time Factors | 1989 |
Inhibition of cyclooxygenase-independent platelet aggregation by sodium salicylate.
Topics: Adult; Aspirin; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate; Thromboxane A2 | 1989 |
Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway.
Topics: Animals; Aspirin; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Heparin; Humans; In Vitro Techniques; Monocytes; Platelet Activating Factor; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
Modulation of resynthesis of 1-alkyl-2-arachidonyl-glycero-3-phosphocholine and phosphatidylinositols for interception in vivo of free arachidonic acid, lyso-PAF, diacyl-glycerols, and phosphoinositides.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Diglycerides; Disease Models, Animal; Flavonoids; Ginkgo biloba; Hemostatics; Humans; Lysophosphatidylcholines; Pain; Pain Measurement; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor; Swine | 1989 |
Effects of ethanol on human platelets stimulated with platelet-activating factor, a biologically active ether phospholipid.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Ethanol; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2 | 1989 |
Platelet aggregation in the Asian elephant is not dependent on thromboxane B2 production.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Elephants; Female; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Verapamil | 1989 |
Endothelin-induced sudden death and the possible involvement of platelet activating factor (PAF).
Topics: Animals; Aspirin; Azepines; Blood Pressure; Death, Sudden; Dexamethasone; Diltiazem; Electrocardiography; Endothelins; Guinea Pigs; Hypertension; Hypotension; Male; Mice; Mice, Inbred ICR; Peptides; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Triazines; Triazoles | 1989 |
Effect of therapy on platelet activating factor-induced aggregation in acute stroke.
Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Drug Therapy, Combination; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 1989 |
Role of leukotrienes and platelet activating factor in acute gastric mucosal lesions in rats.
Topics: Animals; Aspirin; Chromones; Diterpenes; Ethanol; Gastric Mucosa; Ginkgolides; Lactones; Leukotrienes; Male; Masoprocol; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer; Stress, Psychological; Taurocholic Acid | 1989 |
Influence of inhibitors of the eicosanoid metabolism, and of eicosanoids- and PAF-acether antagonists on mortality and some biochemical parameters of three shock models.
Topics: Anaphylaxis; Animals; Aspirin; Diterpenes; Fatty Acids, Unsaturated; Female; Ginkgolides; Imidazoles; Ketotifen; Lactones; Masoprocol; Mice; Naphthalenes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock; Shock, Septic | 1989 |
Presence of paf-acether in human thymus.
Topics: Animals; Aspirin; Blood Platelets; Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Platelet Activating Factor; Rabbits; Thymus Gland | 1989 |
Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
Topics: Animals; Aspirin; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Endotoxins; Female; Furans; Hypertension, Pulmonary; Hypoxia; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Thromboxanes; Zymosan | 1987 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
Topics: Animals; Aspirin; Coronary Circulation; Coronary Vessels; Diphenhydramine; Dogs; Histamine H1 Antagonists; Male; Methacholine Compounds; Methysergide; Nitroglycerin; Platelet Activating Factor; Thrombocytopenia; Vasodilation | 1986 |
Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells.
Topics: Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Aspirin; Cells, Cultured; Chromatography, High Pressure Liquid; Cycloheximide; Dose-Response Relationship, Drug; Endothelium; Hirudins; Humans; Interleukin-1; Lipopolysaccharides; Platelet Activating Factor | 1986 |
PAF-induced platelet aggregation and TXB2 formation.
Topics: Aspirin; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2 | 1989 |
Background and discovery of lipocortins.
Topics: Animals; Annexins; Anti-Inflammatory Agents; Aspirin; Glucocorticoids; Glycoproteins; Humans; Inflammation; Lung; Macrophages; Phospholipases; Platelet Activating Factor; Prostaglandins; Steroids | 1986 |
The effect of AD6 (8-monochloro-3-beta-diethylamino-ethyl-4-methyl-7-ethoxy- carbonylmethoxycoumarin) on washed human platelet aggregation induced by platelet activating factor (PAF) and epinephrine.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aspirin; beta-Thromboglobulin; Blood Platelets; Chromonar; Coumarins; Drug Interactions; Epinephrine; Humans; In Vitro Techniques; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles | 1986 |
Mechanism of the inhibition of platelet aggregation produced by prostaglandin F2 alpha.
Topics: Adenosine Diphosphate; Aspirin; Cyclic AMP; Cyclic GMP; Dinoprost; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins F; Prostaglandins H; Prostaglandins, Synthetic; Thrombin | 1985 |
Synergistic actions of PAF-acether and sodium arachidonate in human platelet aggregation. 1. Studies in normal human platelet rich plasma.
Topics: Adult; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lipoxygenase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2; Time Factors | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Effects of the specific platelet-activating factor antagonists, BN 52021 and BN 52063, on various experimental gastrointestinal ulcerations.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Diterpenes; Endotoxins; Ethanol; Female; Gastric Mucosa; Ginkgolides; Humans; In Vitro Techniques; Intestinal Mucosa; Lactones; Male; Plant Extracts; Platelet Activating Factor; Pylorus; Rats; Rats, Inbred Strains; Salmonella enteritidis; Stomach Ulcer | 1988 |
Platelet aggregating substance from mononuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Catechols; Humans; In Vitro Techniques; Masoprocol; Monocytes; Platelet Activating Factor; Platelet Aggregation | 1986 |
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones | 1986 |
Inhibition by antioxidants of agonist evoked cytosolic Ca++ increase, ATP secretion and aggregation of aspirinated human platelets.
Topics: Adenosine Triphosphate; Antioxidants; Aspirin; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Calcium; Egtazic Acid; Ferrous Compounds; Humans; Masoprocol; Organometallic Compounds; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Effects of inhibitors of arachidonic acid metabolism on Paf-induced gastric mucosal necrosis and haemoconcentration.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Pressure; Dexamethasone; Gastric Mucosa; Hematocrit; Male; Necrosis; Platelet Activating Factor; Prednisolone; Pyrazoles; Rats; Rats, Inbred Strains | 1986 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Aspirin; Cyclooxygenase Inhibitors; Dexamethasone; Edema; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Sodium Salicylate | 1986 |
The effect of PAF (platelet-activating factor) on experimental cardiac arrhythmias and its inhibition by substances influencing arachidonic acid metabolites.
Topics: Animals; Arachidonic Acids; Arrhythmias, Cardiac; Aspirin; Fibrinolytic Agents; Guinea Pigs; Lipoxygenase Inhibitors; Ouabain; Platelet Activating Factor; Sulfonamides; Umbelliferones | 1987 |
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin | 1987 |
A lethal role of platelet activating factor in anaphylactic shock in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Dexamethasone; Male; Mice; Mice, Inbred Strains; Naloxone; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; SRS-A; Thiazoles | 1987 |
Increased airways responsiveness to histamine induced by platelet activating factor in the guinea-pig: possible role of lipoxygenase metabolites.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Atropine Derivatives; Bronchi; Female; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase; Male; Masoprocol; Platelet Activating Factor; Pyrazoles; Vagotomy | 1988 |
The effect of drugs which affect the arachidonate cascade in burned rabbits.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation; Blood Platelets; Burns; Epoprostenol; Fibrinolysis; Kidney; Methacrylates; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Thromboxane-A Synthase | 1986 |
Why single daily dose of aspirin may not prevent platelet aggregation.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Drug Synergism; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2 | 1988 |
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Role of leukotrienes in acute gastric lesions induced by ethanol, taurocholate, aspirin, platelet-activating factor and stress in rats.
Topics: Animals; Aspirin; Chromones; Dinoprostone; Ethanol; Female; Gastric Mucosa; Male; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer; Stress, Physiological; Taurocholic Acid | 1988 |
Inhibition of platelet aggregation by manoalide: preliminary results.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Platelet Activating Factor; Platelet Aggregation; Rabbits; Terpenes | 1988 |
Diltiazem potentiates the inhibitory effect of aspirin on platelet aggregation.
Topics: Arachidonic Acids; Aspirin; Diltiazem; Drug Synergism; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1988 |
Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium.
Topics: Acetylcholine; Animals; Aspirin; Dinoprostone; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Platelet Activating Factor; Prostaglandins E; Serotonin; SRS-A; Thromboxane B2; Trachea | 1987 |
Evidence of PAF release and platelet activation in analgesics-asthma-syndrome.
Topics: Aspirin; Asthma; Blood Platelets; Collagen; Drug Synergism; Female; Humans; Male; Platelet Activating Factor; Syndrome | 1987 |
Potentiation and inhibition by clonidine of PAF-acether-induced human platelet activation.
Topics: Aspirin; Blood Platelets; Clonidine; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation | 1987 |
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Edema; Indomethacin; Inflammation; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Thrombocytopenia | 1987 |
Defective platelet aggregation induced by platelet activating factor in myeloproliferative disorders: deficiency of an aspirin-independent mechanism?
Topics: Adult; Aged; Aspirin; Drug Synergism; Epinephrine; Female; Humans; In Vitro Techniques; Male; Middle Aged; Myeloproliferative Disorders; Platelet Activating Factor; Platelet Aggregation | 1986 |
Contribution of ADP to the amplification of primary platelet aggregation by platelet activating factor (PAF): modulatory role of aspirin.
Topics: Adenosine Diphosphate; Aspirin; Creatine Kinase; Drug Interactions; Humans; Kinetics; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation | 1986 |
Mechanism of PAF-induced platelet aggregation in man.
Topics: Adult; Aspirin; Blood Platelets; Calcium Channel Blockers; Diterpenes; Female; Ginkgolides; Humans; Kinetics; Lactones; Male; Masoprocol; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Trifluoperazine | 1986 |
Relative roles of leukotrienes and platelet activating factor in experimentally-induced gastric ulceration.
Topics: Animals; Aspirin; Benzofurans; Ethanol; Gastric Mucosa; Intestinal Mucosa; Lignans; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; SRS-A; Stomach Ulcer | 1986 |
Ultrastructural evidence for extravascular platelet recruitment in the lung upon intravenous injection of platelet-activating factor (PAF-acether) to guinea-pigs.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Bronchi; Constriction, Pathologic; Epoprostenol; Female; Guinea Pigs; Lung; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Time Factors | 1985 |
Amplification of primary response of human platelets to platelet-activating factor: aspirin-sensitive and aspirin-insensitive pathways.
Topics: Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Resistance; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1985 |
Human platelet aggregation and release reaction induced by platelet activating factor (PAF-acether)--effects of acetylsalicylic acid and external ionized calcium.
Topics: Aspirin; Blood Platelets; Calcium Chloride; Cyclooxygenase Inhibitors; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thromboxane B2 | 1985 |
Platelet-aggregation response to single or paired aggregating stimuli after low-dose aspirin.
Topics: Adult; Arachidonic Acids; Aspirin; Drug Synergism; Epinephrine; Humans; Male; Platelet Activating Factor; Platelet Aggregation | 1986 |
Functional and biochemical characterization of immunologically derived equine platelet-activating factor.
Topics: Animals; Antigens, Helminth; Ascaris; Aspirin; Blood Platelets; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Horses; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Leukocytes; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1985 |
Release of a slow-reacting substance from rabbit platelets.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Platelets; Chromatography, High Pressure Liquid; Cysteine; Indomethacin; Kinetics; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin | 1981 |
Human platelet activation by an alkylacetyl analogue of phosphatidylcholine.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Coagulation Factors; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Epinephrine; Epoprostenol; Humans; Ion Channels; Platelet Activating Factor; Platelet Aggregation; Serotonin | 1982 |
Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2.
Topics: Aminoquinolines; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Spectrometry, Fluorescence | 1984 |
Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Enzyme Activation; Epinephrine; Humans; Indomethacin; Kinetics; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Thrombin; Trifluoperazine; Type C Phospholipases | 1984 |
Effects of tris on responses of human and rabbit platelets to aggregating agents.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serotonin; Thrombin; Tromethamine | 1984 |
Aggregation of bovine platelets by acetyl glyceryl ether phosphorylcholine (platelet activating factor).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; In Vitro Techniques; Inflammation; Platelet Activating Factor; Platelet Aggregation | 1984 |
Triggering by Paf-acether and adrenaline of cyclo-oxygenase-independent platelet aggregation.
Topics: Adenosine Triphosphate; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin; Yohimbine | 1984 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
Acute effects of intratracheal administration of platelet-activating factor in baboons.
Topics: Anesthesia, Local; Animals; Aspirin; Atropine; Bronchi; Bronchial Spasm; Lidocaine; Papio; Platelet Activating Factor; Time Factors; Trachea | 1983 |
Total and selective desensitisation of human platelets to synthetic platelet activating factor (PAF): evidence that extracellular PAF does not mediate collagen-induced aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Extracellular Space; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1983 |
Platelet activating factor: regulation by mast cells and aspirin.
Topics: Animals; Aspirin; Cell Separation; Kinetics; Mast Cells; Platelet Activating Factor; Platelet Aggregation; Rats; Rats, Inbred Strains | 1984 |
One, two, three or more pathways for platelet aggregation.
Topics: Acetophenones; Adenosine Diphosphate; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thrombin; Thromboxane A2 | 1980 |
Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Carrageenan; Cyclooxygenase Inhibitors; Edema; Hyperalgesia; Indomethacin; Lysophosphatidylcholines; Platelet Activating Factor; Rats | 1981 |
Platelet activating factor (PAF) causes human platelet aggregation through the mechanism of membrane modulation.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Membrane; Epinephrine; Epoprostenol; Humans; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Time Factors | 1982 |
Stimulus-response coupling in human platelets. Evidence against a role of PAF-acether in the "third pathway'.
Topics: Aspirin; Blood Platelets; Creatine Kinase; Humans; In Vitro Techniques; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Thrombin | 1983 |
Study of platelet aggregation induced by platelet activating factor (PAF) after administration of ticlopidine or aspirin.
Topics: Adult; Aged; Anticoagulants; Aspirin; Epinephrine; Humans; In Vitro Techniques; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Thiophenes; Ticlopidine | 1983 |
Aggregation of equine platelets by PAF (platelet-activating factor).
Topics: Animals; Aspirin; Blood Platelets; Cells, Cultured; Depression, Chemical; Horses; Platelet Activating Factor; Platelet Aggregation | 1983 |
Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Epoprostenol; In Vitro Techniques; Lysophosphatidylcholines; Platelet Activating Factor; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxane A2; Time Factors | 1980 |
Effect of platelet-activating factor (PAF) on human platelets.
Topics: Animals; Antimycin A; Aspirin; Blood Platelets; Cattle; Creatine Kinase; Deoxyglucose; Epoprostenol; Humans; Indomethacin; Lysophosphatidylcholines; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Platelet Factor 4; Serotonin | 1982 |
Relaxation of the guinea-pig trachea induced by platelet-activating factor and by serotonin.
Topics: Acetylcholine; Animals; Aspirin; Blood Platelets; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lysophosphatidylcholines; Male; Methysergide; Muscle Relaxation; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Serotonin; Trachea | 1982 |
Adrenaline and PAF-acether synergize to trigger cyclooxygenase-independent activation of plasma-free human platelets.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Creatine Kinase; Drug Synergism; Epinephrine; Humans; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Rabbits; Stimulation, Chemical; Thromboxane B2 | 1982 |
PAF effects on eicosanoid release in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Aspirin; Azepines; Cyclooxygenase Inhibitors; Epoprostenol; Heart; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxane A2; Triazoles | 1995 |
Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cell Adhesion; Dinoprostone; Dogs; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Indomethacin; Leukocytes; Leukotriene C4; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfhydryl Compounds; Tetrazoles; Thiophenes | 1995 |
Protein-tyrosine kinase p72syk is activated by platelet activating factor in platelets.
Topics: Animals; Apyrase; Aspirin; Blood Platelets; Calcium; Enzyme Activation; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Phospholipid Ethers; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Stimulation, Chemical; Swine; Syk Kinase | 1994 |
Myocardial ischaemia induces platelet activation with adverse electrophysiological and arrhythmogenic effects.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Biphenyl Compounds; Blood Platelets; Colforsin; Diterpenes; Electrophysiology; Ginkgolides; Guinea Pigs; Heart; Heptanoic Acids; Lactones; Male; Myocardial Ischemia; Oxidopamine; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Yohimbine | 1994 |
The effects of aspirin and paracetamol on the aggregation of equine blood platelets.
Topics: Acetaminophen; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Size; Collagen; Dose-Response Relationship, Drug; Horses; In Vitro Techniques; Nephelometry and Turbidimetry; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1994 |
Endotoxin-induced platelet aggregation in heparinised equine whole blood in vitro.
Topics: Animals; Apyrase; Aspirin; Dose-Response Relationship, Drug; Endotoxins; Heparin; Horses; In Vitro Techniques; Limulus Test; Microscopy; Microscopy, Electron; Nephelometry and Turbidimetry; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation | 1994 |
Effects of aspirin on platelet-neutrophil interactions. Role of nitric oxide and endothelin-1.
Topics: Animals; Aspirin; Blood Platelets; Calcium; Citrulline; Cyclic GMP; Endothelins; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Rabbits | 1995 |
Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema.
Topics: Ajmaline; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Carbon Radioisotopes; Carrageenan; Edema; Humans; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Rats; Shock | 1993 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Effect of various drugs on adriamycin-enhanced venous thrombosis in the rat: importance of PAF.
Topics: Animals; Aspirin; Clopidogrel; Dose-Response Relationship, Drug; Doxorubicin; Leukocyte Count; Male; Platelet Activating Factor; Platelet Count; Rats; Rats, Sprague-Dawley; Thiazoles; Thrombophlebitis; Ticlopidine | 1994 |
Molecular determinants of aspirin-induced neutrophil adherence to endothelial cells.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Aspirin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Flow Cytometry; Fluorescent Antibody Technique; Humans; Infant, Newborn; Intercellular Adhesion Molecule-1; Leukotriene B4; Neutrophils; Platelet Activating Factor; Umbilical Veins | 1993 |
Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Areca; Aspirin; Chromatography, Liquid; Edema; Humans; Plants, Medicinal; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Sitosterols; Triterpenes | 1993 |
Roles of prostacyclin, EDRF and active oxygens in leukocyte-dependent platelet adhesion to endothelial cells induced by platelet-activating factor in vitro.
Topics: Animals; Arginine; Aspirin; Endothelium; Epoprostenol; Female; Humans; In Vitro Techniques; Neutrophils; Nitric Oxide; Nitroarginine; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Pregnancy; Rabbits; Reactive Oxygen Species | 1993 |
Aspirin induces non-enzymatic formation of platelet-activating factor from lyso platelet-activating factor.
Topics: Animals; Aspirin; Biological Assay; Chromatography, Thin Layer; In Vitro Techniques; Kinetics; Platelet Activating Factor; Platelet Aggregation; Rabbits; Time Factors | 1993 |
Acetylsalicylic acid inhibits anticardiolipin antibody-induced platelet-activating factor (PAF) synthesis.
Topics: Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Humans; Hydrogen-Ion Concentration; Platelet Activating Factor; Pregnancy; Pregnancy Complications | 1993 |
The differential effect of aspirin on human platelet activation in aspirin-sensitive asthmatics and normal subjects.
Topics: Adenosine Triphosphate; Adult; Analysis of Variance; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; Male; Middle Aged; Platelet Activating Factor; Platelet Aggregation; Regression Analysis | 1993 |
Sodium fluoride induced activation of phospholipase C in intact human platelets does not depend on ADP, PAF or arachidonate products.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Enzyme Activation; GTP-Binding Proteins; Humans; Lysine; Phospholipid Ethers; Platelet Activating Factor; Sodium Fluoride; Type C Phospholipases | 1993 |
Platelet-activating factor and not thromboxane A2 is an important mediator of endotoxin-induced platelet aggregation in equine heparinised whole blood in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azepines; Carbazoles; Clonixin; Endotoxins; Heparin; Horses; In Vitro Techniques; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinacrine; Thromboxane A2; Triazoles | 1996 |
Differential expression of platelet activation markers in aspirin-sensitive asthmatics and normal subjects.
Topics: Adult; Antigens, CD; Arachidonic Acid; Aspirin; Asthma; Blood Platelets; Cell Adhesion Molecules; Collagen; Drug Hypersensitivity; Drug Interactions; Female; Flow Cytometry; Humans; Male; Middle Aged; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Tetraspanin 30 | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Inhibitory effect of sulfur-containing compounds in Scorodocarpus borneensis Becc. on the aggregation of rabbit platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Blood Coagulation Factors; Collagen; Hemostatics; Hexanes; Inhibitory Concentration 50; Octanes; Plant Extracts; Plants, Edible; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Sulfur Compounds; Thrombin; Trees; Vasoconstrictor Agents | 1999 |
Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation.
Topics: Airway Resistance; Animals; Aspirin; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Chloroquine; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Interleukin-6; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Receptors, Thromboxane; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 1999 |
alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels.
Topics: Adrenergic alpha-Agonists; Aspirin; Blood Platelets; Brimonidine Tartrate; Calcium; Calcium Chloride; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Epinephrine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandins E; Pyrroles; Quinoxalines; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Thapsigargin; Thimerosal; Thrombin; Time Factors | 2000 |
Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Aspirin; Blood Platelets; Cell Communication; Dipyridamole; Drug Synergism; Flow Cytometry; Humans; Leukocytes; Macrophage-1 Antigen; Monocytes; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors | 2001 |
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Diterpenes; Female; Fibrinolytic Agents; Ginkgolides; In Vitro Techniques; Indicators and Reagents; Lactones; Male; Plant Extracts; Plant Roots; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Spiraea | 2002 |
Presence of platelet-activating factor in nasal polyps and eosinophils.
Topics: Aspirin; Asthma; Chromatography, Thin Layer; Drug Hypersensitivity; Eosinophils; Humans; Leukocyte Count; Leukotrienes; Nasal Mucosa; Nasal Polyps; Platelet Activating Factor; Radioimmunoassay | 2002 |
Antiplatelet activity of benzylisoquinoline derivatives oxidized by cerium(IV) ammonium nitrate.
Topics: Arachidonic Acid; Aspirin; Benzylisoquinolines; Cerium; Collagen; Nitrates; Oxidation-Reduction; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship; Thrombin | 2003 |
Biological basis and clinical implications of acetylsalicylic acid resistance.
Topics: Acetylation; Acetyltransferases; Arachidonic Acid; Aspirin; Drug Resistance; Fibrinolytic Agents; Humans; Myocardial Infarction; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Stroke; Thromboxane A2 | 2006 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Edema; Foot; Hindlimb; Histamine; Indomethacin; Injections, Intraperitoneal; Leukocytes; Lipoxins; Male; Mice; Neutrophil Infiltration; Oligopeptides; Platelet Activating Factor; Pleurisy; Receptors, Lipoxin | 2006 |
Platelet activation triggered by Chlamydia pneumoniae is antagonized by 12-lipoxygenase inhibitors but not cyclooxygenase inhibitors.
Topics: Adenosine Triphosphate; Adult; Aspirin; Caffeic Acids; Cell Line, Tumor; Chlamydophila pneumoniae; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Flavanones; Humans; Lipoxygenase Inhibitors; Piroxicam; Platelet Activating Factor; Platelet Aggregation; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12 | 2007 |
Enhanced platelet aggregation and activation under conditions of hypothermia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Monophosphate; Anticoagulants; Antigens, CD; Aspirin; Blood Platelets; Blood Specimen Collection; Citrates; Cold Temperature; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hirudins; Humans; Hypothermia, Induced; In Vitro Techniques; P-Selectin; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Platelet Membrane Glycoproteins; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Receptors, Thrombin; Tetraspanin 30; Time Factors | 2007 |
Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses.
Topics: Animals; Aspirin; Azepines; Benzamides; Blood Platelets; Calcimycin; Female; Horses; Leukocytes; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; Serotonin; Thromboxane A2; Time Factors; Triazoles; Tryptamines; Vasoconstriction | 2008 |
Association between the efficacy of dual antiplatelet therapy and the development of in-stent neointimal hyperplasia in porcine coronary arteries.
Topics: Adenosine Diphosphate; Angioplasty, Balloon, Coronary; Animals; Aspirin; Cell Proliferation; Clopidogrel; Collagen; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Fibrin; Hyperplasia; Inflammation Mediators; Metals; P-Selectin; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Prosthesis Design; Stents; Swine; Ticlopidine; Time Factors; Tunica Intima | 2008 |
Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing.
Topics: Aspirin; Blood Platelets; High-Throughput Screening Assays; Humans; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Reproducibility of Results | 2011 |
[Interaction of the Humoral Agonist During the Platelets Activation in Patients with Chronic Cerebral Ischemia].
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Brain; Brain Ischemia; Chronic Disease; Epinephrine; Female; Humans; Intracranial Thrombosis; Male; Microcirculation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation Inhibitors; Serotonin | 2015 |
Leukotrienes and sex: strange bedfellows?
Topics: Aspirin; Asthma; Eicosanoids; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Platelet Activating Factor | 2017 |
Nucleoside alkaloids with anti-platelet aggregation activity from the rhizomes of
Topics: Alkaloids; Aspirin; Humans; Ligusticum; Molecular Structure; Nucleosides; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rhizome | 2019 |
[ON THE ISSUE OF SELECTION OF COAGULANTS UNDER ADP-INDUCED IMPEDANCE TEST OF AGGREGATION OF THROMBOCYTES IN PATIENTS WITH CHRONIC MYELO-PROLIFERATIVE TUMORS].
Topics: Adenosine Triphosphate; Adult; Aged; Anticoagulants; Aspirin; Blood Platelets; Citrates; Electric Impedance; Female; Healthy Volunteers; Heparin; Hirudins; Humans; Male; Middle Aged; Myeloproliferative Disorders; Platelet Activating Factor; Platelet Aggregation | 2017 |