Page last updated: 2024-09-02

1-hexadecyl-2-acetyl-glycero-3-phosphocholine and allopurinol

1-hexadecyl-2-acetyl-glycero-3-phosphocholine has been researched along with allopurinol in 31 studies

Compound Research Comparison

Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Recent Studies (post-2010)
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
Studies
(allopurinol)
Trials
(allopurinol)
Recent Studies (post-2010) (allopurinol)
9,15618755215,0967433,363

Protein Interaction Comparison

ProteinTaxonomy1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19906 (19.35)18.7374
1990's20 (64.52)18.2507
2000's5 (16.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirano, T; Manabe, T1
Levine, BA; McCollum, MO; Olson, MS; Zhou, W1
Analouei, AR; Corcoran, PC; Foegh, ML; Katz, NM; Rajan, SS; Wallace, RB; Wang, Y1
Fenton, JW; Gudewicz, PW; Kaplan, JE; Moon, DG; van der Zee, H; Weston, LK1
Kondo, M; Naito, Y; Oyamada, H; Sugino, S; Takemura, T; Ueda, S; Yoshida, N; Yoshikawa, T1
Liu, T; Makowka, L; Nalesnik, M; Walsh, TR1
Braquet, P; Drouet, Y; Droy-Lefaix, MT; Géraud, G2
Cueva, JP; Hsueh, W1
Makowka, L; Ontell, SJ; Ove, P; Starzl, TE1
Homeister, JW; Jackson, CV; Lucchesi, BR; Mickelson, JK1
Hill, CE; Olson, MS1
Hiraishi, S; Ishii, H; Kazama, M1
Hashikura, Y; Ikegami, T; Kawasaki, S; Makuuchi, M; Matsunami, H; Nakazawa, Y1
Bel-Haouari, M; Boudjema, K; Chenard, MP; Cinqualbre, J; Doghmi, M; Jaeck, D; Takada, Y; Wolf, P1
Anderson, DC; Gaboury, JP; Kubes, P1
Gaboury, J; Granger, DN; Kubes, P; Reinhardt, P; Woodman, RC1
Andrassy, RJ; Musemeche, CA; Pizzini, RP1
Baroggi, N; Braquet, P; Defaux, JP; Etienne, A; Thonier, F1
Anger, T; Beger, HG; Gansauge, F; Gansauge, S; Nilsson, U; Poch, B; Schoenberg, MH1
Closa, D; Gelpí, E; Hotter, G; Pi, F; Prats, N; Roselló-Catafau, J1
Ambrosio, G; Chiariello, M; Condorelli, M; Napoli, C; Palumbo, G; Triggiani, M1
Bjursten, LM; Schmid-Schönbein, GW; Tung, DK; Zweifach, BW1
Brunet, J; Farine, JC; Garay, RP; Hannaert, P1
Bulkley, GB; Hsueh, W; Huang, W; Qu, XW; Rozenfeld, RA1
Elizalde, JI; Granger, DN; Panés, J; Piqué, JM; Salas, A1
Bulkley, GB; Patel, M; Takada, T; Takano, M; Tien, N; Yamakawa, Y1
Closa, D; Folch, E; Gelpí, E; Panés, J; Piqué, JM; Prats, N; Roselló-Catafau, J; Salas, A1
Baker, CJ; Barr, ML; Darbinian, SH; Kim, JD; Marcus, KA; Quardt, SM; Roberts, RF; Starnes, VA1
Degawa, H; Hama, K; Iwamoto, H; Kikuchi, K; Kozaki, K; Kozaki, M; Matsuno, N; Nagao, T; Narumi, Y; Takeuchi, H; Uchiyama, M1
Hara, M; Ishida, S; Korthuis, RJ; Sakata, T; Shigematsu, S; Takahashi, N; Yoshimatsu, H1

Reviews

1 review(s) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and allopurinol

ArticleYear
Interaction of the formed elements of blood with the coronary vasculature in vivo.
    Federation proceedings, 1987, Volume: 46, Issue:1

    Topics: Animals; Blood Cells; Coronary Disease; Coronary Thrombosis; Coronary Vessels; Dogs; Endothelium; Free Radicals; Leukocytes; Oxygen; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Vasodilation; Xanthine Oxidase

1987

Other Studies

30 other study(ies) available for 1-hexadecyl-2-acetyl-glycero-3-phosphocholine and allopurinol

ArticleYear
"Cocktail" therapy for acute pancreatitis: combined therapy of protease inhibitor, xanthine oxidase inhibitor and platelet activating factor antagonist in rat caerulein-induced pancreatis.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1992, Nov-01, Volume: 61, Issue:6

    Topics: Acute Disease; Allopurinol; Animals; Ceruletide; Drug Therapy, Combination; Gabexate; Male; Pancreatitis; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar; Xanthine Oxidase

1992
Inflammation and platelet-activating factor production during hepatic ischemia/reperfusion.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:5

    Topics: Alanine Transaminase; Allopurinol; Animals; Azepines; Gadolinium; Hepatitis; Ischemia; Leukocytes; Liver; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triazoles

1992
Platelet activating factor antagonist enhances lung preservation in a canine model of single lung allotransplantation.
    The Journal of thoracic and cardiovascular surgery, 1992, Volume: 104, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Deferoxamine; Diterpenes; Dogs; Ginkgolides; Glutathione; Insulin; Lactones; Lung; Lung Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Platelet Activating Factor; Raffinose; Reperfusion Injury; Solutions; Tissue Preservation

1992
Platelet modulation of neutrophil superoxide anion production.
    Thrombosis and haemostasis, 1990, Feb-19, Volume: 63, Issue:1

    Topics: Adenosine; Animals; Blood Platelets; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Sheep; Superoxides; Thrombin; Xanthine Oxidase

1990
Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats.
    Journal of clinical gastroenterology, 1990, Volume: 12 Suppl 1

    Topics: Allopurinol; Animals; Burns; Female; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Hyperthermia, Induced; Lipid Peroxidation; Male; Oxygen; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Reperfusion Injury; Shock, Traumatic

1990
Improved preservation of the rat liver for orthotopic liver transplantation: use of University of Wisconsin-lactobionate solution and retrograde reflushing.
    Surgery, 1990, Volume: 108, Issue:5

    Topics: Adenosine; Allopurinol; Animals; Bile; Free Radical Scavengers; Glutathione; Hypertonic Solutions; Insulin; Liver; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Organ Size; Perfusion; Platelet Activating Factor; Quinolinium Compounds; Raffinose; Rats; Rats, Inbred Lew; Solutions; Survival Rate; Time Factors; Tissue Survival

1990
Effect of the platelet-activating factor (PAF) antagonist, BN 52021, on free radical-induced intestinal ischemia-reperfusion damage in the rat.
    Advances in experimental medicine and biology, 1990, Volume: 264

    Topics: Allopurinol; Animals; Dimethyl Sulfoxide; Diterpenes; Female; Free Radicals; Ginkgolides; Intestinal Diseases; Intestinal Mucosa; Ischemia; Lactones; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase

1990
Role of oxygen derived free radicals in platelet activating factor induced bowel necrosis.
    Gut, 1988, Volume: 29, Issue:9

    Topics: Allopurinol; Animals; Catalase; Enterocolitis, Pseudomembranous; Free Radicals; Hypotension; Intestinal Mucosa; Intestines; Male; Mesenteric Arteries; Oxygen; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasoconstriction

1988
The amplificative role of PAF-acether in the oxidative stress following reperfusion of ischemic stomach.
    Basic life sciences, 1988, Volume: 49

    Topics: Allopurinol; Animals; Female; Free Radicals; Gastric Mucosa; Ischemia; Necrosis; Platelet Activating Factor; Rats; Rats, Inbred Strains; Reference Values; Reperfusion Injury; Stomach; Superoxide Dismutase

1988
Improved hepatic function in the 24-hour preserved rat liver with UW-lactobionate solution and SRI 63-441.
    Gastroenterology, 1988, Volume: 95, Issue:6

    Topics: Adenosine; Allopurinol; Animals; Glutathione; Hypertonic Solutions; Insulin; Liver; Male; Organ Preservation; Organ Preservation Solutions; Platelet Activating Factor; Quinolinium Compounds; Raffinose; Rats; Rats, Inbred Lew; Solutions; Time Factors

1988
Stimulation of uric acid release from the perfused rat liver by platelet activating factor or potassium.
    The Biochemical journal, 1987, Oct-01, Volume: 247, Issue:1

    Topics: Allopurinol; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Glucose; In Vitro Techniques; Liver; Male; Oxygen Consumption; Perfusion; Platelet Activating Factor; Potassium; Rats; Rats, Inbred Strains; Stimulation, Chemical; Uric Acid

1987
A platelet aggregating substance contained in xanthine oxidase preparation from cow's milk.
    Thrombosis research, 1982, Oct-01, Volume: 28, Issue:1

    Topics: Allopurinol; Animals; Blood Coagulation Factors; Blood Platelets; Cattle; Chromatography, Gel; Humans; In Vitro Techniques; Milk; Molecular Weight; Platelet Activating Factor; Platelet Aggregation; Serotonin; Xanthine Oxidase

1982
Effect of platelet-activating factor on cold-preserved liver grafts.
    The British journal of surgery, 1994, Volume: 81, Issue:12

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cryopreservation; Glutathione; Insulin; Liver; Liver Transplantation; Male; Organ Preservation Solutions; Oxygen Consumption; Platelet Activating Factor; Raffinose; Rats; Rats, Wistar

1994
Effects of platelet-activating factor antagonist on preservation/reperfusion injury of the graft in porcine orthotopic liver transplantation.
    Transplantation, 1995, Jan-15, Volume: 59, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Glutathione; Graft Rejection; Insulin; Leukocyte Count; Liver; Liver Transplantation; Microscopy, Electron; Mitochondria, Liver; Organ Preservation Solutions; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Raffinose; Reperfusion Injury; Swine; Tissue Preservation; Transaminases

1995
Molecular mechanisms involved in superoxide-induced leukocyte-endothelial cell interactions in vivo.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; Blood Pressure; Catalase; CD18 Antigens; Endothelium, Vascular; Free Radical Scavengers; Hypoxanthine; Hypoxanthines; Leukocytes; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Receptors, Leukocyte-Adhesion; Splanchnic Circulation; Superoxides; Triazoles; Xanthine Oxidase

1994
Nitric oxide prevents leukocyte adherence: role of superoxide.
    The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 2

    Topics: Animals; Cell Adhesion; Free Radical Scavengers; Hypoxanthine; Hypoxanthines; Leukocytes; Leukotriene B4; Male; Mesentery; Microcirculation; Nitric Oxide; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Xanthine Oxidase

1993
Intestinal ischemia in the newborn: the role of intestinal maturation.
    The Journal of surgical research, 1993, Volume: 55, Issue:6

    Topics: alpha-Glucosidases; Animals; Animals, Newborn; Hydrocortisone; Intestines; Ischemia; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Xanthine Oxidase

1993
Involvement of platelet-activating factor (PAF) in endotoxin- or ischaemia-induced intestinal hyperpermeability in the rat.
    Journal of lipid mediators, 1993, Volume: 7, Issue:1

    Topics: Allopurinol; Animals; Azepines; Endotoxins; Free Radical Scavengers; Intestinal Mucosa; Intestines; Male; Permeability; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Thienopyridines; Triazoles; Xanthine Oxidase

1993
Release of histamine in whole blood by oxygen radicals: division between specific and unspecific processes.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:8

    Topics: Cell Adhesion Molecules; Electron Spin Resonance Spectroscopy; Fluorescent Antibody Technique, Indirect; Granulocytes; Histamine; Histamine Release; Humans; Hypoxanthine; L-Lactate Dehydrogenase; L-Selectin; Monocytes; Platelet Activating Factor; Reactive Oxygen Species; Spin Trapping; Xanthine Oxidase

1996
Free radical enhancement promotes leucocyte recruitment through a PAF and LTB4 dependent mechanism.
    Free radical biology & medicine, 1997, Volume: 22, Issue:6

    Topics: Animals; Diterpenes; Free Radicals; Ginkgolides; Indoles; Lactones; Leukotriene B4; Lipase; Male; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1997
Glycosylation enhances oxygen radical-induced modifications and decreases acetylhydrolase activity of human low density lipoprotein.
    Basic research in cardiology, 1997, Volume: 92, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Analysis of Variance; Copper Sulfate; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Glycation End Products, Advanced; Humans; Lipoproteins, LDL; Phospholipases A; Platelet Activating Factor; Reference Values; Regression Analysis; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1997
Leukocyte contribution to parenchymal cell death in an experimental model of inflammation.
    Journal of leukocyte biology, 1997, Volume: 62, Issue:2

    Topics: Animals; Cell Death; Chemotaxis, Leukocyte; Endothelium; Inflammation; Male; Mesentery; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; Triazines; Xanthine Oxidase

1997
In vitro antioxidant properties of calcium dobesilate.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Animals; Antioxidants; Aorta; Calcium; Calcium Dobesilate; Cattle; Cells, Cultured; Endothelium, Vascular; Erythrocyte Membrane; Free Radical Scavengers; Hemostatics; Humans; Hydroxyl Radical; Lipid Peroxidation; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Potassium; Superoxides; Xanthine; Xanthine Oxidase

1998
The role of xanthine oxidase in platelet activating factor induced intestinal injury in the rat.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Allopurinol; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium; Ileum; Male; Necrosis; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Xanthine Dehydrogenase; Xanthine Oxidase

1999
Reperfusion-induced oxidative stress in diabetes: cellular and enzymatic sources.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Diabetes Mellitus, Experimental; Free Radicals; Intercellular Adhesion Molecule-1; Leukotriene B4; Male; Monocytes; Neutrophils; Oxidative Stress; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Streptozocin; Superoxide Dismutase; Xanthine Oxidase

1999
Interaction of platelet activating factor, reactive oxygen species generated by xanthine oxidase, and leukocytes in the generation of hepatic injury after shock/resuscitation.
    Annals of surgery, 2000, Volume: 231, Issue:3

    Topics: Animals; Disease Models, Animal; Drug Interactions; Leukocytes; Liver; Male; Oxidative Stress; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Time Factors; Xanthine Oxidase

2000
H(2)O(2) and PARS mediate lung P-selectin upregulation in acute pancreatitis.
    Free radical biology & medicine, 2000, Apr-15, Volume: 28, Issue:8

    Topics: Acute Disease; Amylases; Animals; Benzamides; Catalase; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Hydrogen Peroxide; Lipase; Lung; Male; P-Selectin; Pancreatitis; Peroxidase; Platelet Activating Factor; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Respiratory Distress Syndrome; Superoxide Dismutase; Taurocholic Acid; Xanthine Oxidase

2000
Platelet activating factor acetylhydrolase decreases lung reperfusion injury.
    The Annals of thoracic surgery, 2000, Volume: 70, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adenosine; Allopurinol; Animals; Glutathione; Hypertonic Solutions; In Vitro Techniques; Insulin; Lung; Male; Organ Preservation Solutions; Oxidative Stress; Phospholipases A; Platelet Activating Factor; Raffinose; Rats; Rats, Inbred Lew; Reperfusion Injury

2000
Beneficial effect of machine perfusion preservation on liver transplantation from non-heart-beating donors.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Cold Temperature; Endothelin Receptor Antagonists; Glutathione; Graft Survival; Heart Arrest; Hyaluronic Acid; Insulin; L-Lactate Dehydrogenase; Liver; Liver Transplantation; Organ Preservation; Organ Preservation Solutions; Peptides, Cyclic; Perfusion; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Raffinose; Swine; Transplantation, Homologous

2000
Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants.
    Free radical biology & medicine, 2003, Apr-01, Volume: 34, Issue:7

    Topics: Animals; Antioxidants; Cell Adhesion; Flavonoids; Free Radicals; Hypoxanthine; Inflammation; Leukocytes; Leukotriene B4; Male; Oxidants; Phenols; Platelet Activating Factor; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Time Factors; Xanthine Oxidase

2003